Pub Date : 2025-11-01DOI: 10.1016/j.anpede.2025.503996
Marta Andreu-Martínez , Malena Pena-Lahoz , Diego De Juan-Vázquez , Patricia Rodríguez-Lorenzo , Santiago Mintegi
{"title":"Impact of systematic screening in Emergency departments for urinary tract infection in infants 3 to 6 months of age with fever without a source","authors":"Marta Andreu-Martínez , Malena Pena-Lahoz , Diego De Juan-Vázquez , Patricia Rodríguez-Lorenzo , Santiago Mintegi","doi":"10.1016/j.anpede.2025.503996","DOIUrl":"10.1016/j.anpede.2025.503996","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"103 5","pages":"Article 503996"},"PeriodicalIF":0.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145433321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-01DOI: 10.1016/j.anpede.2025.503956
Marta Pacio Miguez , Sixto García-Miñaúr , Ángela del Pozo , Juan José Menéndez Suso , Francisco J. Climent Alcalá , María Sánchez Holgado , Patricia Álvarez García , Carmen Jiménez Rodríguez , Fernando Santos-Simarro , María Palomares-Bralo
Rapid genome sequencing has been found to be an effective tool for the diagnosis of genetic disorders in neonatal and pediatric intensive care settings, allowing rapid and accurate decision-making and access to personalized care and therapies. Most genetic disorders exhibit significant clinical and genetic heterogeneity, which complicates recognition of the disease and diagnosis by conventional methods. Rapid genome sequencing offers a superior diagnostic yield, improving patient management and reducing diagnostic delay and inpatient care costs. However, there are barriers to its implementation in everyday clinical practice, such as a lack of technological infrastructure and qualified professionals. This study, conducted in a Spanish center, demonstrated the viability of genomic medicine in real-world practice, with a diagnostic yield of 42% and a significant impact on the management of patients in 32.5% of cases.
{"title":"Rapid genome sequencing in neonatal and pediatric intensive care units. Evidence and current situation","authors":"Marta Pacio Miguez , Sixto García-Miñaúr , Ángela del Pozo , Juan José Menéndez Suso , Francisco J. Climent Alcalá , María Sánchez Holgado , Patricia Álvarez García , Carmen Jiménez Rodríguez , Fernando Santos-Simarro , María Palomares-Bralo","doi":"10.1016/j.anpede.2025.503956","DOIUrl":"10.1016/j.anpede.2025.503956","url":null,"abstract":"<div><div>Rapid genome sequencing has been found to be an effective tool for the diagnosis of genetic disorders in neonatal and pediatric intensive care settings, allowing rapid and accurate decision-making and access to personalized care and therapies. Most genetic disorders exhibit significant clinical and genetic heterogeneity, which complicates recognition of the disease and diagnosis by conventional methods. Rapid genome sequencing offers a superior diagnostic yield, improving patient management and reducing diagnostic delay and inpatient care costs. However, there are barriers to its implementation in everyday clinical practice, such as a lack of technological infrastructure and qualified professionals. This study, conducted in a Spanish center, demonstrated the viability of genomic medicine in real-world practice, with a diagnostic yield of 42% and a significant impact on the management of patients in 32.5% of cases.</div></div>","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"103 5","pages":"Article 503956"},"PeriodicalIF":0.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145472608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-01DOI: 10.1016/j.anpede.2025.503968
Irati Goienetxe Muñoz, Frederic Samson
{"title":"Controversies in the selection of needle length for intraosseous vascular access cannulation","authors":"Irati Goienetxe Muñoz, Frederic Samson","doi":"10.1016/j.anpede.2025.503968","DOIUrl":"10.1016/j.anpede.2025.503968","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"103 4","pages":"Article 503968"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145276710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-01DOI: 10.1016/j.anpede.2025.503965
Javier Alvarez Aldeán , Francisco José Alvarez García , Marta Cruz Cañete , María Fernández Prada , Laura Francisco González , Ana María Grande Tejada , Antonio Iofrío de Arce , Alejandra Méndez Sánchez , Fernando Moraga Llop , Ignacio Salamanca de la Cueva , en representación del Comité Asesor de Vacunas de la Asociación Española, de Pediatría (CAV-AEP), Sociedad Española de Infectología Pediátrica (SEIP) y Asociación Española de Vacunología (AEV)
Influenza is an important public health problem that puts healthcare systems to the test each year with outbreaks that constitute a significant social and economic burden. The proportion of the pediatric population affected during the annual influenza season ranges between 30% and 40% worldwide, with 2–4 million severe cases in children under 18 years of age globally. Children and adolescents are also the main transmitters of the disease.
The consensus document presented here was developed jointly by three scientific societies: the Spanish Association of Vaccinology (AEV), the Spanish Association of Pediatrics, through its Advisory Committee on Vaccines and Immunizations (CAV-AEP), and the Spanish Society of Pediatric Infectious Diseases (SEIP). Routine influenza vaccination is recommended for children from 6 months of age and for adolescents up to 17 years of age (both included). Vaccination is also recommended for any individual that could transmit the virus to groups at increased risk of developing severe forms of disease and for household or close contacts of infants aged less than 6 months. Vaccination against influenza of all health care professionals as well as pregnant women (at any time during pregnancy) is especially important. For children aged 2 years or older and adolescents, unless contraindicated, vaccination with attenuated intranasal vaccine is preferred. Efforts should be made to improve influenza vaccination coverage in all the recommended groups, with particular emphasis on at-risk groups.
{"title":"Seasonal influenza vaccination in childhood and adolescence. Consensus of the AEV, CAV-AEP and SEIP","authors":"Javier Alvarez Aldeán , Francisco José Alvarez García , Marta Cruz Cañete , María Fernández Prada , Laura Francisco González , Ana María Grande Tejada , Antonio Iofrío de Arce , Alejandra Méndez Sánchez , Fernando Moraga Llop , Ignacio Salamanca de la Cueva , en representación del Comité Asesor de Vacunas de la Asociación Española, de Pediatría (CAV-AEP), Sociedad Española de Infectología Pediátrica (SEIP) y Asociación Española de Vacunología (AEV)","doi":"10.1016/j.anpede.2025.503965","DOIUrl":"10.1016/j.anpede.2025.503965","url":null,"abstract":"<div><div>Influenza is an important public health problem that puts healthcare systems to the test each year with outbreaks that constitute a significant social and economic burden. The proportion of the pediatric population affected during the annual influenza season ranges between 30% and 40% worldwide, with 2–4 million severe cases in children under 18 years of age globally. Children and adolescents are also the main transmitters of the disease.</div><div>The consensus document presented here was developed jointly by three scientific societies: the Spanish Association of Vaccinology (AEV), the Spanish Association of Pediatrics, through its Advisory Committee on Vaccines and Immunizations (CAV-AEP), and the Spanish Society of Pediatric Infectious Diseases (SEIP). Routine influenza vaccination is recommended for children from 6 months of age and for adolescents up to 17 years of age (both included). Vaccination is also recommended for any individual that could transmit the virus to groups at increased risk of developing severe forms of disease and for household or close contacts of infants aged less than 6 months. Vaccination against influenza of all health care professionals as well as pregnant women (at any time during pregnancy) is especially important. For children aged 2 years or older and adolescents, unless contraindicated, vaccination with attenuated intranasal vaccine is preferred. Efforts should be made to improve influenza vaccination coverage in all the recommended groups, with particular emphasis on at-risk groups.</div></div>","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"103 4","pages":"Article 503965"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145276784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-01DOI: 10.1016/j.anpede.2025.503985
María Ruiz Medina , Fernando Vázquez Rueda , María Rosa Ibarra Rodríguez , Rosa Ortega Salas , Rosa María Paredes Esteban
{"title":"Giant borderline mucinous cystoadenoma of the ovary","authors":"María Ruiz Medina , Fernando Vázquez Rueda , María Rosa Ibarra Rodríguez , Rosa Ortega Salas , Rosa María Paredes Esteban","doi":"10.1016/j.anpede.2025.503985","DOIUrl":"10.1016/j.anpede.2025.503985","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"103 4","pages":"Article 503985"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145331037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Infantile orbital hemangioma: A case report","authors":"Rachid Bouchikh-El Jarroudi , Hugo González-Valdivia , Mariana Planells-Alduvín , Mariana Alvarez-Vukov","doi":"10.1016/j.anpede.2025.503967","DOIUrl":"10.1016/j.anpede.2025.503967","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"103 4","pages":"Article 503967"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145182349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-01DOI: 10.1016/j.anpede.2025.503957
Gema Martínez Espinosa , David Muñoz-Santanach
{"title":"Simulation-based activities: How to get started?","authors":"Gema Martínez Espinosa , David Muñoz-Santanach","doi":"10.1016/j.anpede.2025.503957","DOIUrl":"10.1016/j.anpede.2025.503957","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"103 4","pages":"Article 503957"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145276844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-01DOI: 10.1016/j.anpede.2025.503998
Dolores Beteta Fernández , Carlos Pérez Cánovas , Rosa Belén Martínez Egea , Julián Alcaraz Martínez , Adriana Catarina De Souza Oliveira , Manuel Pardo Rios , Grupo de Trabajo RISeuP-SPERG
Introduction
Pediatric emergency departments are high-risk environments for patient safety due to the workload, time pressure and clinical vulnerability of the population. However, there is limited evidence regarding the prevalence, characteristics and associated factors of safety incidents in this setting. Understanding these events is essential to design effective improvement strategies.
Objective
To estimate the incidence of patient safety incidents in pediatric emergency departments, describe their characteristics and identify associated factors. Multicenter, observational and descriptive study based on retrospective chart review and structured incident reporting.
Methods
We identified a total of 1102 pediatric patients treated in the emergency departments of nine Spanish hospitals during the second quarter of 2021 were identified. After excluding 49 patients who could not be reached for follow-up, the final sample included 1056 cases. Of these, 90 children experienced incidents related to healthcare, with a total of 94 incidents, as four patients experienced two incidents each. A previously validated tool was used to collect demographic, clinical and organizational data, as well as information on safety incidents. Results: The overall proportion of patients with at least one safety incident was 8.5% (95%CI: 6.0–9.0). Most incidents caused no harm (39%) or mild to moderate harm (46%), and 13% were deemed clearly preventable. Incidents mainly occurred during emergency care and were attributed to organizational, communication or human factors. There were significant differences between hospitals (P < .01), but we found no associations with shift, triage level, or mode of arrival. The hospital continued to be a significant predictor in the multivariate analysis.
Conclusions
Patient safety incidents in pediatric emergency departments are frequent and partly preventable. The variability observed between centers, which persisted after adjusting for the catchment pediatric population and staffing characteristics, suggests the influence of structural and cultural factors specific to each institution. Context-adapted institutional strategies need to be implemented to foster a proactive safety culture and effective risk management.
{"title":"Safety incidents in pediatric emergency departments: Incidence, characteristics, and variability between centers. A national multicenter study","authors":"Dolores Beteta Fernández , Carlos Pérez Cánovas , Rosa Belén Martínez Egea , Julián Alcaraz Martínez , Adriana Catarina De Souza Oliveira , Manuel Pardo Rios , Grupo de Trabajo RISeuP-SPERG","doi":"10.1016/j.anpede.2025.503998","DOIUrl":"10.1016/j.anpede.2025.503998","url":null,"abstract":"<div><h3>Introduction</h3><div>Pediatric emergency departments are high-risk environments for patient safety due to the workload, time pressure and clinical vulnerability of the population. However, there is limited evidence regarding the prevalence, characteristics and associated factors of safety incidents in this setting. Understanding these events is essential to design effective improvement strategies.</div></div><div><h3>Objective</h3><div>To estimate the incidence of patient safety incidents in pediatric emergency departments, describe their characteristics and identify associated factors. Multicenter, observational and descriptive study based on retrospective chart review and structured incident reporting.</div></div><div><h3>Methods</h3><div>We identified a total of 1102 pediatric patients treated in the emergency departments of nine Spanish hospitals during the second quarter of 2021 were identified. After excluding 49 patients who could not be reached for follow-up, the final sample included 1056 cases. Of these, 90 children experienced incidents related to healthcare, with a total of 94 incidents, as four patients experienced two incidents each. A previously validated tool was used to collect demographic, clinical and organizational data, as well as information on safety incidents. Results: The overall proportion of patients with at least one safety incident was 8.5% (95%CI: 6.0–9.0). Most incidents caused no harm (39%) or mild to moderate harm (46%), and 13% were deemed clearly preventable. Incidents mainly occurred during emergency care and were attributed to organizational, communication or human factors. There were significant differences between hospitals (P < .01), but we found no associations with shift, triage level, or mode of arrival. The hospital continued to be a significant predictor in the multivariate analysis.</div></div><div><h3>Conclusions</h3><div>Patient safety incidents in pediatric emergency departments are frequent and partly preventable. The variability observed between centers, which persisted after adjusting for the catchment pediatric population and staffing characteristics, suggests the influence of structural and cultural factors specific to each institution. Context-adapted institutional strategies need to be implemented to foster a proactive safety culture and effective risk management.</div></div>","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"103 4","pages":"Article 503998"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145369344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}