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Patient and public involvement in the management and prevention of cardiovascular disease: a statement of the Association of Cardiovascular Nursing and Allied Professions of the ESC and the ESC Patient Forum. 患者和公众参与心血管疾病的管理和预防:ESC心血管护理和相关专业协会和ESC患者论坛的声明。
IF 3.9 Pub Date : 2026-01-05 DOI: 10.1093/eurjcn/zvaf191
Jeroen M Hendriks, Paul McGreavy, Suzanne Fredericks, Ian Jones, James Ainslie, Ana Gomes, Julie Sanders

Patient and public involvement (PPI) plays a pivotal role in enhancing the management and prevention of cardiovascular disease (CVD), at multiple levels. The partnership with patients and the public, those who are directly affected by CVD, is central to delivering personalized care, and may contribute to decreasing the burden of CVD and reducing health inequalities. This statement describes the concept of PPI and highlights the role of PPI across different settings including: clinical practice, research, regulatory processes, and policy and clinical guideline development. Recognition of the value of PPI and how to create environments and infrastructure to embed PPI into these areas requires further attention, specifically for under-represented communities. Therefore, considerations for good practice as well as future directions for improvement are provided. Whilst the content of this paper focusses on CVD, the insights provided can be applied to other conditions.

患者和公众参与(PPI)在多个层面上加强心血管疾病(CVD)的管理和预防方面发挥着关键作用。与直接受心血管疾病影响的患者和公众建立伙伴关系,对于提供个性化护理至关重要,并可能有助于减轻心血管疾病负担和减少卫生不平等现象。本声明描述了PPI的概念,并强调了PPI在不同环境中的作用,包括:临床实践、研究、监管过程、政策和临床指南制定。认识到生产者指数的价值,以及如何创造环境和基础设施将生产者指数纳入这些领域,需要进一步关注,特别是对代表性不足的社区。因此,提供了对良好实践的考虑以及未来改进的方向。虽然本文的内容集中在CVD,提供的见解可以应用于其他条件。
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引用次数: 0
Is transitional care intervention effective in improving health outcomes for post-percutaneous coronary intervention patients? A systematic review and meta-analysis of randomized controlled trials. 过渡性护理干预对改善经皮冠状动脉介入治疗后患者的健康状况有效吗?随机对照试验的系统回顾和荟萃分析。
IF 3.9 Pub Date : 2026-01-04 DOI: 10.1093/eurjcn/zvaf192
Li Qiao, Sijia Li, Haoming Ma, Wenchao Zhou, Jianping Zhang, Xingyi Tang, Rongrong Huang, Aoqi Wang, Meihua Piao

Aims: This study aimed to systematically synthesize the currently available body of literature on the impact of transitional care intervention on health outcomes in patients after percutaneous coronary intervention (PCI), focusing on clinical outcomes such as readmission rates, major adverse cardiovascular events (MACE), left ventricular ejection fraction (LVEF), and patient-reported outcomes such as 6 min walk test (6-MWT), quality of life (QoL), and symptoms of anxiety and depression. Furthermore, the study examined the relationship between intervention dosage (including duration, components, and intensity) and improvement in patient health outcomes.

Methods and results: A comprehensive search was conducted across multiple databases from their inception to November 2024, adhering to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. This search included randomized controlled trials (RCTs) aimed at assessing the effects of transitional care on postoperative outcomes in patients undergoing PCI. Softer R was used to perform meta-analysis. Twenty-seven studies involving 3345 participants were included. The meta-analysis results showed that transitional care interventions significantly reduced the readmission risk (RR = 0.56, 95% CI: [0.32, 0.98], I2 = 51.7%) and MACE (RR = 0.32, 95% CI: [0.19, 0.53], I2 = 0%). The QoL was significantly improved (SMD = 0.66, 95% CI: [0.31, 1.00], I2 = 89.5%). Furthermore, these interventions had a positive effect on LVEF (SMD = 0.62, 95% CI: [0.24, 1.00], I2 = 65.5%) and 6-MWT (SMD = 0.67, 95% CI: [0.26, 1.08], I2 = 83.0%). Also, they contributed to the reduction of anxiety (SMD = -0.59, 95% CI: [-0.97, -0.22], I2 = 85.6%) and depression (SMD = -0.82, 95% CI: [-1.53, -0.12], I2 = 95.4%) symptoms in patients.

Conclusion: Transitional care has been shown to have a positive impact on both clinical (e.g. readmissions, MACE, LVEF) and patient-reported (e.g. 6-MWT, QoL, anxiety, depression) outcomes post-PCI. It would be beneficial for future research to prioritize personalized plans based on patient and contextual factors to optimize effects.

Registration: PROSPERO: CRD42024606447.

目的:本研究旨在系统地综合现有的关于过渡性护理干预对经皮冠状动脉介入治疗(PCI)后患者健康结局影响的文献,重点关注临床结局,如再入院率、主要不良心血管事件(MACE)、左心室射血分数(LVEF),以及患者报告的结局,如6分钟步行测试(6- mwt)、生活质量(QoL)、焦虑和抑郁症状。此外,该研究还检查了干预剂量(包括持续时间、成分和强度)与患者健康结果改善之间的关系。方法和结果:根据系统评价和荟萃分析指南的首选报告项目,在多个数据库中进行了从建立到2024年11月的全面搜索。本研究纳入了随机对照试验(rct),旨在评估过渡性护理对PCI患者术后预后的影响。采用软R进行meta分析。共纳入27项研究,涉及3345名受试者。meta分析结果显示,过渡性护理干预显著降低再入院风险(RR = 0.56, 95% CI: [0.32, 0.98], I2 = 51.7%)和MACE (RR = 0.32, 95% CI: [0.19, 0.53], I2 = 0%)。生活质量明显改善(SMD = 0.66, 95% CI: [0.31, 1.00], I2 = 89.5%)。此外,这些干预措施对LVEF (SMD = 0.62, 95% CI: [0.24, 1.00], I2 = 65.5%)和6-MWT (SMD = 0.67, 95% CI: [0.26, 1.08], I2 = 83.0%)有积极影响。此外,它们还有助于减少患者的焦虑(SMD = -0.59, 95% CI: [-0.97, -0.22], I2 = 85.6%)和抑郁(SMD = -0.82, 95% CI: [-1.53, -0.12], I2 = 95.4%)症状。结论:过渡性护理已被证明对pci后临床(如再入院、MACE、LVEF)和患者报告(如6-MWT、生活质量、焦虑、抑郁)结果均有积极影响。根据患者和环境因素对个性化方案进行优先排序,以优化效果,这将有利于未来的研究。报名:普洛斯彼罗:CRD42024606447。
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引用次数: 0
Association between cumulative low-income status and cardiovascular event incidence and mediating effect of engagement in health behaviour: a retrospective cohort study. 累积低收入状况与心血管事件发生率的关系及参与健康行为的中介作用:一项回顾性队列研究
IF 3.9 Pub Date : 2026-01-04 DOI: 10.1093/eurjcn/zvaf189
Sun Young Shim, Hyeonkyeong Lee, Mona Choi, Hyeon Chang Kim, Chang Gi Park, Hyang Yuol Lee

Aims: Income influences individuals' engagement in health behaviours, which may mediate the relationship between income and cardiovascular event incidence. However, research on the association between cardiovascular event and cumulative low-income status remains limited, as most previous studies have assessed income at a single time point. This study aimed to investigate the association between cumulative low-income status and cardiovascular event incidence and to explore the mediating role of engagement in health behaviour.

Methods and results: In this retrospective cohort study, we analysed national representative data from the Korea Health Panel Survey (2008-2018), including 9284 Korean adults. Cumulative low-income status was defined based on total number of years classified as low-income status during the 3 year baseline. Cardiovascular event incidence was defined as the first diagnosis of myocardial infarction, stroke, or cardiovascular disease-related death. Engagement in health behaviour was measured through smoking, alcohol consumption, and physical activity. After adjusting for covariates, Cox proportional hazard models showed an association between increased risk of cardiovascular event incidence and prolonged cumulative low-income status [1 or 2 years: hazard ratio (HR) = 1.27, 95% confidence interval (CI) = 0.97-1.67; 3 years: HR = 1.33, 95% CI = 1.01-1.77; P for trend = 0.045]. A generalized structural equation model revealed that engagement in negative health behaviour mediated the longitudinal relationship between 1 and 2 years of cumulative low-income status and cardiovascular event incidence (indirect effect estimate = 0.179, P-value = 0.004).

Conclusion: These findings suggest that interventions targeting engagement in health behaviour among population with cumulative low-income status may help prevent cardiovascular events and promote cardiovascular health equity.

目的:收入影响个体参与健康行为,这可能是收入与心血管事件发生率之间的中介关系。然而,关于心血管事件与累积低收入状况之间关系的研究仍然有限,因为大多数先前的研究都是在单个时间点评估收入。本研究旨在探讨累积低收入状况与心血管事件发生率之间的关系,并探讨参与在健康行为中的中介作用。方法和结果:在这项回顾性队列研究中,我们分析了韩国健康小组调查(2008-2018)的全国代表性数据,包括9284名韩国成年人。累积低收入状态是根据3年基线期间归类为低收入状态的总年数来定义的。心血管事件发生率定义为首次诊断为心肌梗死、卒中或心血管疾病相关死亡。参与健康行为是通过吸烟、饮酒和体育活动来衡量的。调整协变量后,Cox比例风险模型显示心血管事件发生率增加与长期累积低收入状态之间存在关联[1或2年:风险比(HR) = 1.27, 95%可信区间(CI) = 0.97-1.67;3年:HR = 1.33, 95% CI = 1.01-1.77;P代表趋势= 0.045]。广义结构方程模型显示,参与消极健康行为介导了1 - 2年累计低收入状况与心血管事件发生率之间的纵向关系(间接效应估计= 0.179,p值= 0.004)。结论:这些发现表明,针对累积低收入人群健康行为的干预措施可能有助于预防心血管事件并促进心血管健康公平。
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引用次数: 0
A pilot randomized controlled trial to test the feasibility of a mobile health (mHealth) self-help intervention for adults after cardiac surgery. 一项试点随机对照试验,旨在测试心脏手术后成人移动健康(mHealth)自助干预的可行性。
IF 3.9 Pub Date : 2026-01-04 DOI: 10.1093/eurjcn/zvaf190
Rochelle Wynne, Joanne Nolte, Jennifer Angel, Andrew Moore, Tina Campbell, Caleb Ferguson

Aims: To determine feasibility, acceptability and test protocol integrity, for testing a mobile health (mHealth) intervention focused on enhancing self-management after adult cardiac surgery. Secondary aims were to assess the effect of the intervention on 30-day readmission, quality of life, and knowledge, skill and confidence for self-help.

Methods and results: A parallel-group, pilot randomized controlled trial was conducted in a major metropolitan publicly funded health service. Adult elective cardiac surgery patients discharged home within 30-days, able to understand spoken English, and use a smartphone, tablet or computer were eligible for inclusion. The mHealth intervention comprised patient narrative videos, and on-line resources focused on diagnosis, preparing for surgery, and immediate, and ongoing recovery. From August 2021 until the 23rd of December 2022, there were 341/516 elective cardiac surgery cases. Of 70 (20.5%) eligible patients, 61 (87.1%) participated. The mHealth intervention was accessed by 27 (84.4%) participants. When accessed, the intervention was feasible and acceptable for patients, there were no protocol violations. There was high viewing of content related to diagnosis, surgery and looking forward, compared with programmes related to rehabilitation. Readmission rates did not differ between groups. Participants taking action to manage their health in the intervention group incrementally increased from baseline to 90-day follow-up.

Conclusion: The effect of patient narratives on patient activation warrants testing in an adequately powered randomized controlled trial. While the uptake of the mHealth intervention was modest, trends in actions for self-help and rate of 30-day readmission imply the intervention is potentially effective in improving self-help management.

Registration: The Australian and New Zealand Clinical Trials Registry: ACTRN12621000082808.

目的:确定可行性、可接受性和测试协议完整性,以测试一种专注于增强成人心脏手术后自我管理的移动健康(mHealth)干预措施。次要目的是评估干预对30天再入院、生活质量、自助知识、技能和信心的影响。方法与结果:在某大城市公费卫生服务机构进行平行组随机对照试验。成人选择性心脏手术患者在30天内出院回家,能够理解英语口语,并使用智能手机,平板电脑或电脑,符合纳入条件。移动医疗干预包括患者叙事视频和在线资源,重点是诊断、手术准备以及即时和持续的康复。从2021年8月至2022年12月23日,有341/516例选择性心脏手术病例。在70例(20.5%)符合条件的患者中,61例(87.1%)参与了研究。27名(84.4%)参与者参与了移动健康干预。当访问时,干预是可行的和可接受的患者,没有违反协议。与康复相关的节目相比,与诊断、手术和展望相关的内容有很高的收视率。两组间再入院率无差异。干预组采取行动管理健康的参与者从基线到90天随访期间逐渐增加。结论:患者叙述对患者激活的影响值得在一项足够有力的随机对照试验中进行测试。虽然移动医疗干预措施的采用程度不高,但自助行动的趋势和30天再入院率表明,该干预措施在改善自助管理方面可能有效。注册:澳大利亚和新西兰临床试验注册中心:ACTRN12621000082808。
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引用次数: 0
Incorporating co-design in cardiovascular research: tips, tricks, and tools. 将共同设计纳入心血管研究:提示、技巧和工具。
IF 3.9 Pub Date : 2026-01-04 DOI: 10.1093/eurjcn/zvaf184
Sara Pettersson, Hanna Allemann, Thomas Grice-Jackson, Jane Holstein, Heleen Westland, Tiny Jaarsma

Co-design is increasingly used in cardiovascular health research. Conducting co-design is an iterative process that involves collaboration with end-users, such as clinicians and people with lived experience. However, co-design is logistically, practically, and methodologically challenging. This methods paper aims to clarify what co-design is, why and when to use co-design, and how co-design research can be conducted. This paper, therefore, provides practical tools and examples to deal with the challenges and achieve a constructive co-design process in cardiovascular research.

协同设计在心血管健康研究中的应用越来越广泛。进行共同设计是一个迭代过程,涉及与最终用户(如临床医生和有实际经验的人)的协作。然而,协同设计在逻辑上、实践上和方法上都具有挑战性。本文旨在阐明什么是协同设计,为什么以及何时使用协同设计,以及如何进行协同设计研究。因此,本文提供了实用的工具和例子来应对这些挑战,并在心血管研究中实现建设性的协同设计过程。
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引用次数: 0
Theoretical implications and considerations of transitional care interventions to improve health outcomes for patients after percutaneous coronary intervention. 经皮冠状动脉介入治疗后过渡性护理干预改善患者健康结果的理论意义和考虑。
IF 3.9 Pub Date : 2026-01-04 DOI: 10.1093/eurjcn/zvaf208
Javier Mauricio Sánchez-Rodríguez, Luis Alberto López-Romero, Diana Marcela Castillo-Sierra, Luisa Fernanda Moscoso-Loaiza
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引用次数: 0
Association between the rate of force development of quadriceps and physical performance in older patients undergoing cardiovascular surgery: a cross-sectional study. 在接受心血管手术的老年患者中,股四头肌力量发展速度与身体表现之间的关系:一项横断面研究。
IF 3.9 Pub Date : 2026-01-03 DOI: 10.1093/eurjcn/zvaf183
Takuji Adachi, Ryosuke Hosono, Taisei Sano, Kenichi Shibata, Hideki Kitamura

Aims: This study aims to assess the association between the quadriceps rate of force development (RFD) and physical performance in older patients undergoing cardiovascular surgery.

Methods and results: A cross-sectional study was conducted with hospitalized patients aged ≥65 years who underwent cardiovascular surgery. Physical performance was evaluated using a Short Physical Performance Battery (SPPB). The 4 m gait speed and time for five repeated chair stands were analysed as secondary outcomes. Ninety-four participants were enrolled (mean age, 75 years; men, 58.5%; median SPPB, 10 points; ≤9 points, 42.6%). Quadriceps isometric strength was measured, and RFD values at two time points (RFD100, 0-100 ms; RFD200, 0-200 ms) were calculated from the slope of the force-time curve. Maximal voluntary contraction (MVC) was also calculated. In all participants, the SPPB was significantly associated with RFD100, RFD200, and MVC. The 4 m gait speed was correlated with RFD100, RFD200, and MVC, and the chair stand test time was negatively correlated with RFD100, RFD200, and MVC. Although these significant associations persisted after adjusting for age, sex, and body mass index or skeletal muscle mass, the association between RFD and physical performance was not significant after adjusting for MVC. Subgroup analysis revealed that the correlation coefficients between RFD and physical performance measures were greater in patients with low muscle mass than in those with preserved muscle mass. Similar results were observed for the secondary outcomes.

Conclusion: Rate of force development and physical performance were significantly correlated after cardiovascular surgery, especially in those with low muscle mass.

目的:本研究旨在评估老年心血管手术患者股四头肌力量发展率(RFD)与身体表现之间的关系。方法和结果:对年龄≥65岁接受心血管手术的住院患者进行横断面研究。使用短物理性能电池(SPPB)评估物理性能。5次重复站立的4米步态速度和时间作为次要结果进行分析。94名参与者入组(平均年龄75岁,男性58.5%,SPPB中位数10分,≤9分,42.6%)。测量股四头肌等距强度,根据力-时间曲线斜率计算两个时间点(RFD100, 0-100 ms; RFD200, 0-200 ms)的RFD值。最大自主收缩(MVC)也被计算。在所有参与者中,SPPB与RFD100、RFD200和MVC显著相关。4 m步速与RFD100、RFD200、MVC呈显著负相关,椅子站立测试时间与RFD100、RFD200、MVC呈显著负相关。尽管在调整了年龄、性别、身体质量指数或骨骼肌质量后,这些显著的关联仍然存在,但在调整了MVC后,RFD与身体表现之间的关联并不显著。亚组分析显示,低肌肉量患者的RFD与体能指标之间的相关系数大于保留肌肉量的患者。在次要结果中也观察到类似的结果。结论:心血管手术后力量发展速度与体能表现显著相关,尤其是低肌肉量患者。
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引用次数: 0
Dynamic trends and influencing factors of self-care behaviours among Chinese older adults with chronic heart failure during vulnerable period: a longitudinal study. 中国老年慢性心力衰竭患者脆弱期自我护理行为动态趋势及影响因素:一项纵向研究
IF 3.9 Pub Date : 2026-01-03 DOI: 10.1093/eurjcn/zvaf197
Yu Chen, Ying Lin, Xinyue Dong, Yan Xue, Dong Wu

Aims: To explore the trends of self-care behaviours among Chinese older adults with chronic heart failure (CHF) during the vulnerable period (VP) and to analyze influencing factors.

Methods and results: This was a longitudinal study. From October 2022 to July 2023, 255 patients were recruited from a tertiary hospital in Shanghai, China. Data regarding self-care behaviours (self-care maintenance, symptom perception, and self-care management), self-care confidence, illness perception, self-efficacy, social support, HF knowledge, and demographic and clinical information were collected during hospitalization (T1) utilizing validated questionnaires and electronic health records. Follow-up behavioural data were collected at 2 weeks (T2), 4 weeks (T3), 2 months (T4), and 3 months (T5) post-discharge. Repeated measures ANOVA was used to identify the trends of self-care behaviours, and the generalized estimation equation was used to explore influencing factors. Self-care maintenance scores reached 70 at T2, T4, and T5, while self-care management scores exceeded 70 at time points from T2 to T5. Symptom perception scores never reached 70 any single time point. There were significant temporal variations across all 3 domains, characterized by a rapid improvement at 2 weeks post-discharge, followed by subsequent stabilization or decline (P < 0.05). Residential area, educational level, cardiac function, self-care confidence, and HF knowledge were key influencing factors (P < 0.05).

Conclusion: Self-care behaviours among patients improved within the first two weeks post-discharge but tended to stabilize or decline thereafter, indicating a critical window for targeted interventions. Health care professionals should tailor self-care promotion strategies to both the temporal patterns of behaviours and patient-specific characteristics.

目的:探讨中国老年慢性心力衰竭(CHF)患者脆弱期(VP)自我护理行为的变化趋势并分析影响因素。方法和结果:这是一项纵向研究。从2022年10月到2023年7月,从中国上海的一家三级医院招募了255名患者。在住院期间(T1),利用有效问卷和电子健康记录收集有关自我保健行为(自我保健维持、症状感知和自我保健管理)、自我保健信心、疾病感知、自我效能感、社会支持、心衰知识以及人口统计学和临床信息的数据。分别于出院后2周(T2)、4周(T3)、2个月(T4)和3个月(T5)收集随访行为数据。采用重复测量方差分析确定自我护理行为的趋势,采用广义估计方程探讨影响因素。自我护理维持评分在T2、T4、T5达到70分,自我护理管理评分在T2 ~ T5时间点均超过70分。症状知觉评分在任何一个时间点均未达到70分。在所有3个领域有显著的时间差异,其特点是在出院后2周迅速改善,随后稳定或下降(P < 0.05)。居住地区、文化程度、心功能、生活自理信心、心衰知识为主要影响因素(P < 0.05)。结论:患者的自我护理行为在出院后的前两周内有所改善,但此后趋于稳定或下降,这是有针对性干预的关键窗口期。卫生保健专业人员应根据行为的时间模式和患者的具体特征定制自我保健促进策略。
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引用次数: 0
Understanding implementation outcomes of cardiovascular rehabilitation for transient ischaemic attack and mild stroke: a process evaluation. 了解短暂性缺血性发作和轻度卒中心血管康复的实施结果:过程评估。
IF 3.9 Pub Date : 2026-01-03 DOI: 10.1093/eurjcn/zvaf181
Lucy Walton, Allyson Flynn, Elisabeth Preston, Rachel Davey, Nicole Freene

Aims: Despite evidence supporting the inclusion of people with transient ischaemic attack (TIA) or mild stroke in cardiac rehabilitation, no process evaluations have investigated the implementation of integrated [TIA, mild stroke, coronary heart disease (CHD)] cardiovascular rehabilitation (CVR). We aimed to identify factors influencing CVR implementation success or failure, and evaluate CVR implementation outcomes, considering reach, effectiveness, adoption, implementation, and maintenance, from clinician perspectives.

Methods and results: This mixed-methods process evaluation was guided by the Reach, Effectiveness, Adoption, Implementation and Maintenance (RE-AIM) framework. Quantitative patient process-level data were collected throughout CVR implementation. Qualitative data (semi-structured interviews, field notes, observations) were collected and deductively coded to the Consolidated Framework for Implementation Research. Quantitative and qualitative data were mapped to the RE-AIM dimensions. Reach was 44% (140/315) of the eligible patient population, with referral adoption highest at site 1 (74%), influenced by larger referral teams and greater programme awareness. Clinicians viewed CVR as effective based on international recommendations, but more evidence is needed. Cardiovascular rehabilitation was delivered as intended, with fidelity linked to adequate staffing and clinician confidence in delivery. Sixty-six per cent (46/70) of patients completed ≥5 of 6 CVR sessions. Clear referral pathways and access to resources are necessary for CVR maintenance.

Conclusion: Cardiovascular rehabilitation was delivered as intended, and clinicians reported people with TIA, mild stroke, and CHD demonstrate similar needs. However, greater programme awareness and aligning referral pathways with existing services are indicated. Access to CVR programme resources and clinicians' confidence in CVR delivery enabled implementation and are essential for maintenance.

Registration: Australian New Zealand Clinical Trials Registry (ANZCTR), ACTRN 12621 00158 6808.

目的:尽管有证据支持将短暂性脑缺血发作(TIA)或轻度卒中患者纳入心脏康复,但没有过程评估调查了综合[TIA,轻度卒中,冠心病]心血管康复(CVR)的实施情况。我们的目的是确定影响CVR实施成功或失败的因素,并从临床医生的角度评估CVR实施的结果,包括覆盖范围、有效性、采用、实施和维护。方法与结果:采用RE-AIM (Reach, Effectiveness, Adoption, Implementation and Maintenance)框架指导混合方法的过程评价。在整个CVR实施过程中收集定量的患者过程级数据。收集了定性数据(半结构化访谈、实地记录、观察结果),并将其演绎编码到实施研究综合框架中。定量和定性数据映射到RE-AIM维度。达到44%(140/315)的符合条件的患者,转诊采用率最高的是1号站点(74%),受更大的转诊团队和更大的项目意识的影响。临床医生根据国际建议认为CVR是有效的,但需要更多的证据。心血管康复如期交付,与足够的人员配备和临床医生对交付的信心有关。66%(46/70)的患者完成了6次CVR疗程中的≥5次。明确的转诊途径和获得资源是维持CVR的必要条件。结论:心血管康复如期进行,临床医生报告TIA、轻度卒中和冠心病患者表现出类似的需求。但是,建议提高对方案的认识,并使转诊途径与现有服务保持一致。获得CVR项目资源和临床医生对CVR交付的信心使CVR得以实施,并对维持至关重要。注册:澳大利亚新西兰临床试验注册中心(ANZCTR), ACTRN 12621 00158 6808。
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引用次数: 0
Effects of a multimodal support intervention (the NICE-Support programme) on frailty and quality of life in patients with heart failure: a randomized controlled trial. 多模式支持干预(NICE-Support program)对心力衰竭患者虚弱和生活质量的影响:一项随机对照试验
IF 3.9 Pub Date : 2026-01-03 DOI: 10.1093/eurjcn/zvaf187
Tzu-Chieh Wang, Yu-Cheng Hsieh, Chiu-Yueh Yang, Chii-Ming Lee, Chieh-Yu Liu, Ai-Fu Chiou

Aims: This randomized controlled trial examined the effectiveness of the 12-week NICE-Support programme-combining nutrition, nursing instruction, exercise, and support-on frailty and quality of life in patients with heart failure.

Methods and results: A total of 240 adults (≥20 years) with stable heart failure, cognitive and physical capacity for activity, and smartphone access were recruited from two Taiwanese medical centres and randomly allocated to either the intervention group or the control group. The 12-week intervention included nutritional counselling, three in-person nursing consultations (40-60 min each), a structured exercise regimen (three 30 min sessions per week), social media support, and biweekly follow-up calls. The control group received standard nursing care and routine discharge education. Frailty and quality of life were assessed at baseline and at 4, 12, and 24 weeks to evaluate short-term and sustained effects. Among the 240 participants, 192 (80%) completed the 24-week follow-up. An intention-to-treat analysis was conducted to evaluate the intervention effects. Both groups showed significant improvements over time. At 24 weeks, the control group demonstrated significant improvements in frailty scores (-8.11 points) and overall quality of life scores (-22.71 points). Compared with the control group, the intervention group exhibited significantly greater improvements in frailty (Cohen's d = 1.17) and overall quality of life (Cohen's d = 0.87) at Week 24.

Conclusion: The NICE-Support programme significantly reduces frailty and improves quality of life in patients with heart failure. Its integration into routine care is recommended.

Registration: ClinicalTrials.gov: NCT05366686.

目的:这项随机对照试验检验了12周nice -支持方案(结合营养、护理指导、运动和支持)对心力衰竭患者虚弱和生活质量的影响。方法和结果:从台湾两家医疗中心招募了240名稳定型心力衰竭、认知和身体活动能力、智能手机接入的成年人(≥20岁),随机分为干预组和对照组。为期12周的干预包括营养咨询、三次面对面护理咨询(每次40-60分钟)、有组织的锻炼方案(每周三次30分钟)、社交媒体支持和每两周一次的随访电话。对照组患者接受标准护理和常规出院教育。在基线、4周、12周和24周时对虚弱和生活质量进行评估,以评估短期和持续效果。在240名参与者中,192名(80%)完成了24周的随访。进行意向治疗分析以评估干预效果。随着时间的推移,两组都有了显著的改善。在24周时,对照组在衰弱评分(-8.11分)和总体生活质量评分(-22.71分)方面有显著改善。与对照组相比,干预组在第24周的虚弱程度(Cohen’s d = 1.17)和总体生活质量(Cohen’s d = 0.87)方面表现出更大的改善。结论:NICE-Support方案可显著降低心力衰竭患者的虚弱并提高其生活质量。建议将其纳入常规护理。注册:ClinicalTrials.gov: NCT05366686。
{"title":"Effects of a multimodal support intervention (the NICE-Support programme) on frailty and quality of life in patients with heart failure: a randomized controlled trial.","authors":"Tzu-Chieh Wang, Yu-Cheng Hsieh, Chiu-Yueh Yang, Chii-Ming Lee, Chieh-Yu Liu, Ai-Fu Chiou","doi":"10.1093/eurjcn/zvaf187","DOIUrl":"https://doi.org/10.1093/eurjcn/zvaf187","url":null,"abstract":"<p><strong>Aims: </strong>This randomized controlled trial examined the effectiveness of the 12-week NICE-Support programme-combining nutrition, nursing instruction, exercise, and support-on frailty and quality of life in patients with heart failure.</p><p><strong>Methods and results: </strong>A total of 240 adults (≥20 years) with stable heart failure, cognitive and physical capacity for activity, and smartphone access were recruited from two Taiwanese medical centres and randomly allocated to either the intervention group or the control group. The 12-week intervention included nutritional counselling, three in-person nursing consultations (40-60 min each), a structured exercise regimen (three 30 min sessions per week), social media support, and biweekly follow-up calls. The control group received standard nursing care and routine discharge education. Frailty and quality of life were assessed at baseline and at 4, 12, and 24 weeks to evaluate short-term and sustained effects. Among the 240 participants, 192 (80%) completed the 24-week follow-up. An intention-to-treat analysis was conducted to evaluate the intervention effects. Both groups showed significant improvements over time. At 24 weeks, the control group demonstrated significant improvements in frailty scores (-8.11 points) and overall quality of life scores (-22.71 points). Compared with the control group, the intervention group exhibited significantly greater improvements in frailty (Cohen's d = 1.17) and overall quality of life (Cohen's d = 0.87) at Week 24.</p><p><strong>Conclusion: </strong>The NICE-Support programme significantly reduces frailty and improves quality of life in patients with heart failure. Its integration into routine care is recommended.</p><p><strong>Registration: </strong>ClinicalTrials.gov: NCT05366686.</p>","PeriodicalId":93997,"journal":{"name":"European journal of cardiovascular nursing","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145893539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
European journal of cardiovascular nursing
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