首页 > 最新文献

Health affairs scholar最新文献

英文 中文
Measuring commercial cannabis availability: findings from a multi-state surveillance study in the US. 衡量商业大麻的可用性:来自美国多州监测研究的结果。
IF 2.7 Pub Date : 2025-11-07 eCollection Date: 2025-12-01 DOI: 10.1093/haschl/qxaf209
Nigar Nargis, Samuel Asare, J Lee Westmaas

Introduction: Cannabis legalization enables greater access to commercial cannabis among adults. Little is known about the extent to which demand for cannabis is met by licit or illicit markets among states with medical-only or recreational cannabis laws, or no legalization.

Methods: Annual sales values of medical and recreational tetrahydrocannabinol (THC), illicit THC, hemp-derived cannabidiol (CBD) and hemp-derived THC were estimated for 2024 in 12 US states by combining and triangulating data from national- and state-level public sources, Euromonitor's Passport database, in-store audits (n = 142), retailer interviews (n = 78), and expert interviews (n = 10) of cannabis industry stakeholders. States were classified into three types of cannabis legalization status.

Results: State-level THC market size was substantial, accounting for ≥90% of the combined cannabis market value of THC and CBD, regardless of legalization status. However, the composition of THC markets-across legal recreational, medical, illicit, and hemp-derived segments-varied considerably, even among states with the same legalization status.

Conclusions: The emergence of hemp-derived THC in both legal and non-legal markets alongside the persistence of illicit THC sales in legal markets highlight regulatory gaps and challenges in market oversight. These findings underscore the need for integrated policy approaches that align enforcement strategies with public health objectives and consumer education.

大麻合法化使成年人更容易获得商业大麻。在只有医用大麻或娱乐大麻法律或没有大麻合法化的国家中,大麻的合法或非法市场在多大程度上满足了对大麻的需求,人们知之甚少。方法:通过对来自国家和州级公共来源、Euromonitor的Passport数据库、店内审计(n = 142)、零售商访谈(n = 78)和大麻行业利益相关者的专家访谈(n = 10)的数据进行组合和三角测量,估计2024年美国12个州医疗和娱乐用四氢大麻酚(THC)、非法THC、大麻衍生大麻二酚(CBD)和大麻衍生四氢大麻酚的年销售额。将大麻合法化状态分为三种类型。结果:无论大麻是否合法,国家层面的四氢大麻酚市场规模都很大,占四氢大麻酚和CBD大麻总市值的90%以上。然而,四氢大麻酚市场的构成——包括合法的娱乐、医疗、非法和大麻衍生部分——差异很大,甚至在具有相同合法化地位的州之间也是如此。结论:大麻衍生的四氢大麻酚在合法和非合法市场的出现,以及合法市场中非法四氢大麻酚销售的持续存在,突显了市场监管方面的空白和挑战。这些调查结果强调需要采取综合政策办法,使执法战略与公共卫生目标和消费者教育保持一致。
{"title":"Measuring commercial cannabis availability: findings from a multi-state surveillance study in the US.","authors":"Nigar Nargis, Samuel Asare, J Lee Westmaas","doi":"10.1093/haschl/qxaf209","DOIUrl":"10.1093/haschl/qxaf209","url":null,"abstract":"<p><strong>Introduction: </strong>Cannabis legalization enables greater access to commercial cannabis among adults. Little is known about the extent to which demand for cannabis is met by licit or illicit markets among states with medical-only or recreational cannabis laws, or no legalization.</p><p><strong>Methods: </strong>Annual sales values of medical and recreational tetrahydrocannabinol (THC), illicit THC, hemp-derived cannabidiol (CBD) and hemp-derived THC were estimated for 2024 in 12 US states by combining and triangulating data from national- and state-level public sources, Euromonitor's Passport database, in-store audits (<i>n</i> = 142), retailer interviews (<i>n</i> = 78), and expert interviews (<i>n</i> = 10) of cannabis industry stakeholders. States were classified into three types of cannabis legalization status.</p><p><strong>Results: </strong>State-level THC market size was substantial, accounting for ≥90% of the combined cannabis market value of THC and CBD, regardless of legalization status. However, the composition of THC markets-across legal recreational, medical, illicit, and hemp-derived segments-varied considerably, even among states with the same legalization status.</p><p><strong>Conclusions: </strong>The emergence of hemp-derived THC in both legal and non-legal markets alongside the persistence of illicit THC sales in legal markets highlight regulatory gaps and challenges in market oversight. These findings underscore the need for integrated policy approaches that align enforcement strategies with public health objectives and consumer education.</p>","PeriodicalId":94025,"journal":{"name":"Health affairs scholar","volume":"3 12","pages":"qxaf209"},"PeriodicalIF":2.7,"publicationDate":"2025-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12666535/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145662964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Global venture capital flows and US health care innovation. 全球风险资本流动与美国医疗保健创新。
IF 2.7 Pub Date : 2025-10-30 eCollection Date: 2025-11-01 DOI: 10.1093/haschl/qxaf206
Yunan Ji, So-Yeon Kang
{"title":"Global venture capital flows and US health care innovation.","authors":"Yunan Ji, So-Yeon Kang","doi":"10.1093/haschl/qxaf206","DOIUrl":"10.1093/haschl/qxaf206","url":null,"abstract":"","PeriodicalId":94025,"journal":{"name":"Health affairs scholar","volume":"3 11","pages":"qxaf206"},"PeriodicalIF":2.7,"publicationDate":"2025-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12611213/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145515406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The unintended health effects of US COVID-19 lockdowns: a systematic review. 美国COVID-19封锁对健康的意外影响:一项系统综述。
IF 2.7 Pub Date : 2025-10-30 eCollection Date: 2025-11-01 DOI: 10.1093/haschl/qxaf208
Heather L Taylor, Pablo Cuadros, MaKenzie Gee, Nir Menachemi

Introduction: US lockdowns and school closures implemented during the COVID-19 pandemic were intended to mitigate viral transmission and protect public health. However, the broader health effects of these interventions remain unclear.

Methods: We conducted a systematic review of peer-reviewed studies that assessed the impact of US lockdowns and school closures on health-related outcomes excluding COVID-19 transmission and mortality.

Results: A total of 132 studies met inclusion criteria, yielding 454 unique outcomes. Lockdowns and school closures were associated with detrimental health effects in the majority of outcomes analyzed, including over 90% of mental health, obesity-related, and health-related social need outcomes (child development/education, employment, access to food, and economic/financial stability). Analyses focused on vulnerable populations, such as racial and ethnic minorities, low-income groups, and individuals with disabilities, were significantly more likely to report detrimental outcomes than the general population.

Conclusion: Given how lockdowns and school closures may affect population well-being, policymakers should carefully weigh both the benefits and harms of these interventions, including how they may affect vulnerable populations. We conclude with policy recommendations to mitigate ongoing harms and inform more evidence-based decision-making.

导语:美国在2019冠状病毒病大流行期间实施的封锁和学校关闭旨在减轻病毒传播并保护公众健康。然而,这些干预措施的更广泛的健康影响仍不清楚。方法:我们对同行评议的研究进行了系统回顾,评估了美国封锁和学校关闭对健康相关结果的影响,但不包括COVID-19传播和死亡率。结果:共有132项研究符合纳入标准,产生454个独特的结果。在分析的大多数结果中,封锁和学校关闭与有害的健康影响有关,包括90%以上的心理健康、肥胖相关和健康相关的社会需求结果(儿童发展/教育、就业、获得食物和经济/金融稳定)。针对弱势群体的分析,如种族和少数民族、低收入群体和残疾人,比一般人群更有可能报告有害的结果。结论:鉴于封锁和学校关闭可能会影响人口福祉,政策制定者应仔细权衡这些干预措施的利弊,包括它们可能如何影响弱势群体。最后,我们提出了政策建议,以减轻持续的危害,并为更多基于证据的决策提供信息。
{"title":"The unintended health effects of US COVID-19 lockdowns: a systematic review.","authors":"Heather L Taylor, Pablo Cuadros, MaKenzie Gee, Nir Menachemi","doi":"10.1093/haschl/qxaf208","DOIUrl":"10.1093/haschl/qxaf208","url":null,"abstract":"<p><strong>Introduction: </strong>US lockdowns and school closures implemented during the COVID-19 pandemic were intended to mitigate viral transmission and protect public health. However, the broader health effects of these interventions remain unclear.</p><p><strong>Methods: </strong>We conducted a systematic review of peer-reviewed studies that assessed the impact of US lockdowns and school closures on health-related outcomes excluding COVID-19 transmission and mortality.</p><p><strong>Results: </strong>A total of 132 studies met inclusion criteria, yielding 454 unique outcomes. Lockdowns and school closures were associated with detrimental health effects in the majority of outcomes analyzed, including over 90% of mental health, obesity-related, and health-related social need outcomes (child development/education, employment, access to food, and economic/financial stability). Analyses focused on vulnerable populations, such as racial and ethnic minorities, low-income groups, and individuals with disabilities, were significantly more likely to report detrimental outcomes than the general population.</p><p><strong>Conclusion: </strong>Given how lockdowns and school closures may affect population well-being, policymakers should carefully weigh both the benefits and harms of these interventions, including how they may affect vulnerable populations. We conclude with policy recommendations to mitigate ongoing harms and inform more evidence-based decision-making.</p>","PeriodicalId":94025,"journal":{"name":"Health affairs scholar","volume":"3 11","pages":"qxaf208"},"PeriodicalIF":2.7,"publicationDate":"2025-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12612676/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145544698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Disability data: a case study in research limitation transparency. 残疾数据:研究限制透明度的案例研究。
IF 2.7 Pub Date : 2025-10-29 eCollection Date: 2025-11-01 DOI: 10.1093/haschl/qxaf205
Scott D Landes, Bonnielin K Swenor, Jean P Hall, Anjali J Forber-Pratt

Disability measures currently used in U.S. federal surveys fail to identify many disabled people as such. This commentary summarizes empirical evidence regarding the underperformance of the American Community Survey six questions (ACS6) and Washington Group Short Set (WGSS) questions in measuring disability status. Building trust in science is a priority issue and necessitates greater transparency and communication about the limitations of these measures, both within research communities and among the public. Considering the underperformance of the ACS6 and WGSS in measuring disability status, we provide cautionary statements that researchers can use when including these measures in studies to ensure that interpretations of results are not overgeneralized to the disabled population.

目前在美国联邦调查中使用的残疾衡量标准未能识别出许多残疾人。这篇评论总结了有关美国社区调查六个问题(ACS6)和华盛顿小组短集(WGSS)问题在衡量残疾状况方面表现不佳的经验证据。建立对科学的信任是一个优先事项,需要在研究界和公众之间就这些措施的局限性提高透明度和沟通。考虑到ACS6和WGSS在衡量残疾状况方面表现不佳,我们提供了一些警示性陈述,供研究人员在研究中包括这些措施时使用,以确保对结果的解释不会过度推广到残疾人群。
{"title":"Disability data: a case study in research limitation transparency.","authors":"Scott D Landes, Bonnielin K Swenor, Jean P Hall, Anjali J Forber-Pratt","doi":"10.1093/haschl/qxaf205","DOIUrl":"10.1093/haschl/qxaf205","url":null,"abstract":"<p><p>Disability measures currently used in U.S. federal surveys fail to identify many disabled people as such. This commentary summarizes empirical evidence regarding the underperformance of the American Community Survey six questions (ACS6) and Washington Group Short Set (WGSS) questions in measuring disability status. Building trust in science is a priority issue and necessitates greater transparency and communication about the limitations of these measures, both within research communities and among the public. Considering the underperformance of the ACS6 and WGSS in measuring disability status, we provide cautionary statements that researchers can use when including these measures in studies to ensure that interpretations of results are not overgeneralized to the disabled population.</p>","PeriodicalId":94025,"journal":{"name":"Health affairs scholar","volume":"3 11","pages":"qxaf205"},"PeriodicalIF":2.7,"publicationDate":"2025-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12606725/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145515371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Medicaid prescription cap policies and exemptions for medications for opioid use disorder: A process and content analysis. 阿片类药物使用障碍的医疗补助处方上限政策和豁免:过程和内容分析。
IF 2.7 Pub Date : 2025-10-27 eCollection Date: 2025-11-01 DOI: 10.1093/haschl/qxaf203
Jaclyn M W Hughto, Stephanie Vento, David R Pletta, Madeline Noh, Theresa I Shireman, Christopher M Santostefano, Landon D Hughes, Lisa Peterson, Emma Seymour, Elizabeth G Stettenbauer, Patience M Dow

Introduction: Some state Medicaid programs place a cap on the monthly number of covered prescription fills, including medications for opioid use disorder (MOUD)-the most effective OUD treatments.

Methods: Between 2023 and 2024, we employed a quasi-systematic 3-step process (online search, survey of Medicaid experts, request-for-information) to identify contemporary Medicaid cap policy information and conducted a content analysis of cap policies.

Results: Of the 12 states with contemporary prescription cap policies, 9 operated general caps and 3 operated caps for controlled substances. Across states, caps ranged from 3-6 monthly prescriptions. All states had exemptions based on beneficiary characteristics (eg, age, health conditions) or medication type (eg, contraceptives, antipsychotics), 6 of which had cap override policies, and 5 had MOUD-specific exemptions.

Conclusion: Our search identified a dearth of publicly accessible, contemporary information on Medicaid cap policies, indicating a potential barrier to beneficiaries' understanding their prescription drug benefits. Further, although all states provided some type of policy carveout, half of the Medicaid programs operating caps did not exempt MOUD, which may negatively impact access to medically necessary medications for Medicaid beneficiaries with OUD.

简介:一些州的医疗补助计划对每月覆盖的处方填充数量设置了上限,包括治疗阿片类药物使用障碍(mod)的药物,这是最有效的OUD治疗方法。方法:在2023年至2024年间,我们采用准系统的三步流程(在线搜索、医疗补助专家调查、信息请求)来识别当代医疗补助上限政策信息,并对上限政策进行内容分析。结果:现行处方限量政策的12个州中,9个州实行一般限量,3个州实行管制药物限量。各州的上限从3-6个月不等。所有州都有基于受益人特征(如年龄、健康状况)或药物类型(如避孕药具、抗精神病药物)的豁免,其中6个州有超过上限的政策,5个州有特定于mod的豁免。结论:我们的研究发现,缺乏关于医疗补助上限政策的可公开获取的当代信息,这表明受益人了解其处方药福利的潜在障碍。此外,尽管所有州都提供了某种类型的政策豁免,但有一半的医疗补助计划运营上限没有免除OUD,这可能会对医疗补助受益人获得医疗必要药物的机会产生负面影响。
{"title":"Medicaid prescription cap policies and exemptions for medications for opioid use disorder: A process and content analysis.","authors":"Jaclyn M W Hughto, Stephanie Vento, David R Pletta, Madeline Noh, Theresa I Shireman, Christopher M Santostefano, Landon D Hughes, Lisa Peterson, Emma Seymour, Elizabeth G Stettenbauer, Patience M Dow","doi":"10.1093/haschl/qxaf203","DOIUrl":"10.1093/haschl/qxaf203","url":null,"abstract":"<p><strong>Introduction: </strong>Some state Medicaid programs place a cap on the monthly number of covered prescription fills, including medications for opioid use disorder (MOUD)-the most effective OUD treatments.</p><p><strong>Methods: </strong>Between 2023 and 2024, we employed a quasi-systematic 3-step process (online search, survey of Medicaid experts, request-for-information) to identify contemporary Medicaid cap policy information and conducted a content analysis of cap policies.</p><p><strong>Results: </strong>Of the 12 states with contemporary prescription cap policies, 9 operated general caps and 3 operated caps for controlled substances. Across states, caps ranged from 3-6 monthly prescriptions. All states had exemptions based on beneficiary characteristics (eg, age, health conditions) or medication type (eg, contraceptives, antipsychotics), 6 of which had cap override policies, and 5 had MOUD-specific exemptions.</p><p><strong>Conclusion: </strong>Our search identified a dearth of publicly accessible, contemporary information on Medicaid cap policies, indicating a potential barrier to beneficiaries' understanding their prescription drug benefits. Further, although all states provided some type of policy carveout, half of the Medicaid programs operating caps did not exempt MOUD, which may negatively impact access to medically necessary medications for Medicaid beneficiaries with OUD.</p>","PeriodicalId":94025,"journal":{"name":"Health affairs scholar","volume":"3 11","pages":"qxaf203"},"PeriodicalIF":2.7,"publicationDate":"2025-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12612678/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145544627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Regional changes in inpatient psychiatric bed capacity and availability of alternative psychiatric services, 2012-2022. 2012-2022年精神科住院床位容量和替代精神科服务可得性的区域变化。
IF 2.7 Pub Date : 2025-10-27 eCollection Date: 2025-11-01 DOI: 10.1093/haschl/qxaf204
Michael X Liu, Emma E McGinty, William L Schpero

Introduction: The US faces a growing mismatch between demand for inpatient psychiatric care and available capacity. Little is known about the characteristics of regions affected by inpatient psychiatric bed shortages, which hospitals have faced decreases in bed supply, and whether other psychiatric services have emerged to fill the gap.

Methods: Using data from the American Hospital Association Annual Survey, we conducted a descriptive analysis of inpatient psychiatric bed supply across hospital referral regions (HRRs) from 2012 to 2022. We examined the demographic patterns of regions affected by shortages, assessed hospital characteristics associated with reductions in psychiatric capacity, and evaluated the presence of alternative psychiatric services that may substitute for inpatient care.

Results: More than 60% of the US population consistently lived in HRRs with psychiatric bed shortages during this period, defined as fewer than 30 beds per 100 000 people. By 2022, HRRs with severe shortages, relative to those without them, were more likely to be in the West and had higher proportions of Hispanic residents, raising concerns about inequities in behavioral health care access. Hospitals most likely to reduce psychiatric capacity were general, non-profit, and system-affiliated institutions with lower total margins. Importantly, hospitals in severe shortage areas were less likely to have outpatient psychiatric services, indicating that alternative hospital-based resources may not fully offset inpatient shortfalls.

Conclusion: Addressing the nation's psychiatric bed shortage will require targeted financial support for general hospitals at risk of closing psychiatric units and investment in broader psychiatric infrastructure to ensure equitable access across regions.

导读:美国面临着住院精神病治疗需求与可用能力之间日益增长的不匹配。对于受住院精神病床位短缺影响的地区的特点,哪些医院面临床位供应减少,以及是否出现了其他精神病服务来填补这一空白,人们知之甚少。方法:利用美国医院协会年度调查的数据,我们对2012年至2022年各医院转诊地区(HRRs)的住院精神病床位供应进行了描述性分析。我们检查了受短缺影响地区的人口统计模式,评估了与精神科能力减少相关的医院特征,并评估了可能替代住院治疗的其他精神科服务的存在。结果:在此期间,超过60%的美国人口一直生活在精神科床位短缺的hrr中,定义为每10万人少于30张床位。到2022年,相对于没有hrr的地区,严重短缺的hrr更有可能在西方,拉美裔居民的比例更高,这引发了人们对行为医疗服务获取不平等的担忧。最有可能减少精神科容量的医院是一般的、非营利性的和总利润较低的系统附属机构。重要的是,严重短缺地区的医院不太可能提供门诊精神科服务,这表明替代的医院资源可能无法完全抵消住院病人的短缺。结论:解决全国精神科床位短缺问题,需要有针对性地为面临关闭精神科病房风险的综合医院提供财政支持,并投资于更广泛的精神科基础设施,以确保各地区的公平准入。
{"title":"Regional changes in inpatient psychiatric bed capacity and availability of alternative psychiatric services, 2012-2022.","authors":"Michael X Liu, Emma E McGinty, William L Schpero","doi":"10.1093/haschl/qxaf204","DOIUrl":"10.1093/haschl/qxaf204","url":null,"abstract":"<p><strong>Introduction: </strong>The US faces a growing mismatch between demand for inpatient psychiatric care and available capacity. Little is known about the characteristics of regions affected by inpatient psychiatric bed shortages, which hospitals have faced decreases in bed supply, and whether other psychiatric services have emerged to fill the gap.</p><p><strong>Methods: </strong>Using data from the American Hospital Association Annual Survey, we conducted a descriptive analysis of inpatient psychiatric bed supply across hospital referral regions (HRRs) from 2012 to 2022. We examined the demographic patterns of regions affected by shortages, assessed hospital characteristics associated with reductions in psychiatric capacity, and evaluated the presence of alternative psychiatric services that may substitute for inpatient care.</p><p><strong>Results: </strong>More than 60% of the US population consistently lived in HRRs with psychiatric bed shortages during this period, defined as fewer than 30 beds per 100 000 people. By 2022, HRRs with severe shortages, relative to those without them, were more likely to be in the West and had higher proportions of Hispanic residents, raising concerns about inequities in behavioral health care access. Hospitals most likely to reduce psychiatric capacity were general, non-profit, and system-affiliated institutions with lower total margins. Importantly, hospitals in severe shortage areas were less likely to have outpatient psychiatric services, indicating that alternative hospital-based resources may not fully offset inpatient shortfalls.</p><p><strong>Conclusion: </strong>Addressing the nation's psychiatric bed shortage will require targeted financial support for general hospitals at risk of closing psychiatric units and investment in broader psychiatric infrastructure to ensure equitable access across regions.</p>","PeriodicalId":94025,"journal":{"name":"Health affairs scholar","volume":"3 11","pages":"qxaf204"},"PeriodicalIF":2.7,"publicationDate":"2025-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12610395/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145515401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Health Affairs Scholar expands its reach with fast-tracked peer review and new article formats to meet today's needs. 卫生事务学者扩大其影响力与快速跟踪同行评审和新的文章格式,以满足当今的需求。
IF 2.7 Pub Date : 2025-10-25 eCollection Date: 2025-11-01 DOI: 10.1093/haschl/qxaf197
William B Feldman, Kathryn A Phillips, Donald E Metz
{"title":"Health Affairs Scholar expands its reach with fast-tracked peer review and new article formats to meet today's needs.","authors":"William B Feldman, Kathryn A Phillips, Donald E Metz","doi":"10.1093/haschl/qxaf197","DOIUrl":"10.1093/haschl/qxaf197","url":null,"abstract":"","PeriodicalId":94025,"journal":{"name":"Health affairs scholar","volume":"3 11","pages":"qxaf197"},"PeriodicalIF":2.7,"publicationDate":"2025-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12587761/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145460987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Understanding biopharmaceutical investment decision-making: how does Congressional Budget Office's model compare to investor insights? 理解生物制药投资决策:国会预算办公室的模型如何与投资者的见解相比较?
IF 2.7 Pub Date : 2025-10-23 eCollection Date: 2025-11-01 DOI: 10.1093/haschl/qxaf200
Matthias P Hofer, Priscila Radu, Mikel Berdud, Amanda Cole, Graham Cookson

The Congressional Budget Office (CBO) created a model of new drug development with the aim of informing the US Congress about the potential impact of policy changes affecting expected biopharmaceutical revenue on future innovation. While models are by their nature simplifications of reality, biopharmaceutical investment decision-making is particularly complex and poorly understood outside the investment ecosystem, raising questions about the adequacy of such models to inform policymaking. To better understand how CBO's model compares to real-world investment decision processes, we conducted semi-structured interviews with investors representing venture capital, private equity, corporate venture capital, and biopharmaceutical companies. The interviews with investors suggest that the CBO's model does not adequately reflect investment decisions for drug development. These findings highlight the risks of using models to guide policymaking and the need to improve the existing model with the help of stakeholder input before such models are adopted.

美国国会预算办公室(CBO)创建了一个新药开发模型,目的是向美国国会通报影响预期生物制药收入的政策变化对未来创新的潜在影响。虽然模型本质上是对现实的简化,但生物制药投资决策特别复杂,而且在投资生态系统之外很难理解,这引发了对这些模型是否足以为决策提供信息的质疑。为了更好地理解CBO的模型与现实投资决策过程的比较,我们对代表风险资本、私募股权、企业风险资本和生物制药公司的投资者进行了半结构化访谈。对投资者的采访表明,国会预算办公室的模型不能充分反映药物开发的投资决策。这些发现突出了使用模型来指导政策制定的风险,以及在采用这些模型之前,需要在利益相关者投入的帮助下改进现有模型。
{"title":"Understanding biopharmaceutical investment decision-making: how does Congressional Budget Office's model compare to investor insights?","authors":"Matthias P Hofer, Priscila Radu, Mikel Berdud, Amanda Cole, Graham Cookson","doi":"10.1093/haschl/qxaf200","DOIUrl":"10.1093/haschl/qxaf200","url":null,"abstract":"<p><p>The Congressional Budget Office (CBO) created a model of new drug development with the aim of informing the US Congress about the potential impact of policy changes affecting expected biopharmaceutical revenue on future innovation. While models are by their nature simplifications of reality, biopharmaceutical investment decision-making is particularly complex and poorly understood outside the investment ecosystem, raising questions about the adequacy of such models to inform policymaking. To better understand how CBO's model compares to real-world investment decision processes, we conducted semi-structured interviews with investors representing venture capital, private equity, corporate venture capital, and biopharmaceutical companies. The interviews with investors suggest that the CBO's model does not adequately reflect investment decisions for drug development. These findings highlight the risks of using models to guide policymaking and the need to improve the existing model with the help of stakeholder input before such models are adopted.</p>","PeriodicalId":94025,"journal":{"name":"Health affairs scholar","volume":"3 11","pages":"qxaf200"},"PeriodicalIF":2.7,"publicationDate":"2025-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12602863/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145508634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Will expanding catastrophic coverage eligibility increase marketplace premium affordability in 2026? 在2026年,扩大灾难保险资格是否会提高市场保费的可承受性?
IF 2.7 Pub Date : 2025-10-23 eCollection Date: 2025-11-01 DOI: 10.1093/haschl/qxaf202
David M Anderson, Dylan Nagy, Coleman Drake
{"title":"Will expanding catastrophic coverage eligibility increase marketplace premium affordability in 2026?","authors":"David M Anderson, Dylan Nagy, Coleman Drake","doi":"10.1093/haschl/qxaf202","DOIUrl":"10.1093/haschl/qxaf202","url":null,"abstract":"","PeriodicalId":94025,"journal":{"name":"Health affairs scholar","volume":"3 11","pages":"qxaf202"},"PeriodicalIF":2.7,"publicationDate":"2025-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12596389/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145490939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Medical debt, financial risk factors, and deferred care among low-wage workers. 低工资工人的医疗债务、财务风险因素和延迟护理。
IF 2.7 Pub Date : 2025-10-22 eCollection Date: 2025-11-01 DOI: 10.1093/haschl/qxaf196
Mathieu Despard, Sally A Hageman, Stephen Roll

Introduction: Medical debt is widely regarded as a social problem that reflects growing out-of-pocket costs. Yet whether medical debt acts a social determinant of health by discouraging people to seek additional care may depend on one's ability to repay this debt.

Methods: We use data from the first wave of a survey of a nationally representative sample of 2090 low-wage workers in the U.S. We ran linear probability models to predict putting off filling prescriptions, receiving primary medical care, and receiving specialty medical care based on medical debt disposition.

Results: We find that workers with medical debt they cannot afford to repay are more likely to defer three types of health care and are confronted with several other financial risk factors compared with workers with medical debt they are repaying. Also, concerning putting off needed health care, there is no difference between workers who are repaying their medical debt and those with no medical debt.

Discussion: These findings suggest the need to strengthen financial assistance policies and programs and ensure access to low-cost health coverage for low-wage workers.

导读:医疗债务被广泛认为是一个社会问题,反映了日益增长的自付费用。然而,医疗债务是否会阻碍人们寻求额外治疗,从而成为健康的社会决定因素,可能取决于一个人偿还这笔债务的能力。方法:我们使用来自美国2090名低收入工人的全国代表性样本的第一波调查数据。我们运行线性概率模型来预测推迟填写处方,接受初级医疗保健和接受基于医疗债务处置的专业医疗保健。结果:我们发现,与正在偿还医疗债务的工人相比,有医疗债务的工人更有可能推迟三种类型的医疗保健,并面临其他几个财务风险因素。此外,在推迟必要的医疗保健方面,正在偿还医疗债务的工人和没有医疗债务的工人之间没有区别。讨论:这些发现表明需要加强财政援助政策和计划,并确保低收入工人获得低成本的医疗保险。
{"title":"Medical debt, financial risk factors, and deferred care among low-wage workers.","authors":"Mathieu Despard, Sally A Hageman, Stephen Roll","doi":"10.1093/haschl/qxaf196","DOIUrl":"10.1093/haschl/qxaf196","url":null,"abstract":"<p><strong>Introduction: </strong>Medical debt is widely regarded as a social problem that reflects growing out-of-pocket costs. Yet whether medical debt acts a social determinant of health by discouraging people to seek additional care may depend on one's ability to repay this debt.</p><p><strong>Methods: </strong>We use data from the first wave of a survey of a nationally representative sample of 2090 low-wage workers in the U.S. We ran linear probability models to predict putting off filling prescriptions, receiving primary medical care, and receiving specialty medical care based on medical debt disposition.</p><p><strong>Results: </strong>We find that workers with medical debt they cannot afford to repay are more likely to defer three types of health care and are confronted with several other financial risk factors compared with workers with medical debt they are repaying. Also, concerning putting off needed health care, there is no difference between workers who are repaying their medical debt and those with no medical debt.</p><p><strong>Discussion: </strong>These findings suggest the need to strengthen financial assistance policies and programs and ensure access to low-cost health coverage for low-wage workers.</p>","PeriodicalId":94025,"journal":{"name":"Health affairs scholar","volume":"3 11","pages":"qxaf196"},"PeriodicalIF":2.7,"publicationDate":"2025-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12605751/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145515424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Health affairs scholar
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1