首页 > 最新文献

Health affairs scholar最新文献

英文 中文
Association of Medicaid expansion with children's insurance coverage and healthcare utilization. 医疗补助扩大与儿童保险覆盖面和医疗保健利用的协会。
IF 2.7 Pub Date : 2025-12-22 eCollection Date: 2026-01-01 DOI: 10.1093/haschl/qxaf245
Kim Dalziel, Kao-Ping Chua, Xinyang Hua, Li Huang, Andrew Ryan, Gary L Freed, Helen Levy, John Z Ayanian

Introduction: In 2014, multiple states expanded Medicaid coverage to low-income adults under the Affordable Care Act. We evaluated the association of Medicaid expansion (ME) with children's insurance coverage and health service utilization.

Methods: We compared changes in children's insurance coverage and health service utilization between 2010-2013 and 2014-2016 in expansion and non-expansion states. Repeated cross-sectional analysis with linear difference-in-differences (DID) models was conducted using the Medical Expenditure Panel Survey.

Results: Medicaid expansion was not associated with changes in the proportion of children with ≥1 month of insurance coverage (DID: -1.9% point [pp], 95% CI -4.1 to 0.3) or the proportion of children with continuous coverage for 12 months (DID: -1.8 pp, 95% CI -5.6 to 2.0). Expansion was not associated with changes in any utilization outcome, including having ≥1 annual well-child visit (DID: -1.9 pp, 95% CI -6.6 to 2.8) or ≥1 annual dental visit (DID: 1.9 pp, 95% CI -2.8 to 6.5).

Conclusion: Medicaid expansion was not associated with changes in children's coverage and utilization. While policymakers in states that have not yet expanded Medicaid might still consider doing so for other reasons, findings suggest that alternative interventions will be needed to improve coverage and utilization patterns in children.

导读:2014年,多个州根据《平价医疗法案》将医疗补助扩大到低收入成年人。我们评估了医疗补助扩大(ME)与儿童保险覆盖面和卫生服务利用率的关系。方法:比较2010-2013年和2014-2016年扩展州和未扩展州儿童保险覆盖率和卫生服务利用率的变化。使用医疗支出面板调查进行了线性差异(DID)模型的重复横断面分析。结果:医疗补助扩大与≥1个月保险覆盖的儿童比例的变化无关(DID: -1.9%点[pp], 95% CI -4.1至0.3)或连续12个月保险覆盖的儿童比例(DID: -1.8 pp, 95% CI -5.6至2.0)。扩展与任何利用结果的改变无关,包括每年≥1次儿童健康检查(DID: -1.9 pp, 95% CI -6.6至2.8)或每年≥1次牙科检查(DID: 1.9 pp, 95% CI -2.8至6.5)。结论:医疗补助扩大与儿童覆盖率和使用率的变化无关。虽然尚未扩大医疗补助的州的政策制定者可能出于其他原因仍会考虑这样做,但研究结果表明,需要其他干预措施来改善儿童的覆盖范围和利用模式。
{"title":"Association of Medicaid expansion with children's insurance coverage and healthcare utilization.","authors":"Kim Dalziel, Kao-Ping Chua, Xinyang Hua, Li Huang, Andrew Ryan, Gary L Freed, Helen Levy, John Z Ayanian","doi":"10.1093/haschl/qxaf245","DOIUrl":"10.1093/haschl/qxaf245","url":null,"abstract":"<p><strong>Introduction: </strong>In 2014, multiple states expanded Medicaid coverage to low-income adults under the Affordable Care Act. We evaluated the association of Medicaid expansion (ME) with children's insurance coverage and health service utilization.</p><p><strong>Methods: </strong>We compared changes in children's insurance coverage and health service utilization between 2010-2013 and 2014-2016 in expansion and non-expansion states. Repeated cross-sectional analysis with linear difference-in-differences (DID) models was conducted using the Medical Expenditure Panel Survey.</p><p><strong>Results: </strong>Medicaid expansion was not associated with changes in the proportion of children with ≥1 month of insurance coverage (DID: -1.9% point [pp], 95% CI -4.1 to 0.3) or the proportion of children with continuous coverage for 12 months (DID: -1.8 pp, 95% CI -5.6 to 2.0). Expansion was not associated with changes in any utilization outcome, including having ≥1 annual well-child visit (DID: -1.9 pp, 95% CI -6.6 to 2.8) or ≥1 annual dental visit (DID: 1.9 pp, 95% CI -2.8 to 6.5).</p><p><strong>Conclusion: </strong>Medicaid expansion was not associated with changes in children's coverage and utilization. While policymakers in states that have not yet expanded Medicaid might still consider doing so for other reasons, findings suggest that alternative interventions will be needed to improve coverage and utilization patterns in children.</p>","PeriodicalId":94025,"journal":{"name":"Health affairs scholar","volume":"4 1","pages":"qxaf245"},"PeriodicalIF":2.7,"publicationDate":"2025-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12778330/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145936877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unwinding of Medicaid enrollment and increased uninsured emergency department visits in California. 在加州,医疗补助登记的解除和无保险急诊就诊的增加。
IF 2.7 Pub Date : 2025-12-22 eCollection Date: 2026-01-01 DOI: 10.1093/haschl/qxaf238
Nima Khodakarami, Theodoros V Giannouchos, Daniel Marthey, Benjamin Ukert, Joel Segel, Laura Dague

Objective: To examine the association between post-pandemic era Medicaid eligibility redeterminations ("unwinding") and emergency department (ED) payer mix in California.

Methods: We conducted a retrospective secondary analysis of California's quarterly ED visit data (2021-2024) across 281 general acute-care hospitals, using interrupted time-series analysis.

Results: During unwinding, Medicaid ED visits declined by 0.37 percentage points (pp) and uninsured ED visits increased by 0.16 pp per quarter (P < .001) relative to the pre-unwinding period. The largest Medicaid declines occurred in investor-owned (0.87 pp, 11.9%) and medium-sized (0.47 pp, 7.4%) hospitals (P < .001). In contrast, the largest increases in uninsured visits occurred among hospitals in rural (0.29 pp, 46.7%) and high-poverty (0.24 pp, 7.7%) areas, in addition to small hospitals (0.22 pp, 25.8%) (P < .001). Private visits saw an immediate decrease of 0.49 pp (P < .001), followed by a continued reduction of 0.15 pp per quarter (P < .05), showing flattening of the previously increasing trend. Medicare visits increased by 0.18 pp per quarter (P < .001) relative to the pre-unwinding period.

Conclusion: Medicaid unwinding was associated with a decline in Medicaid ED visits and a corresponding increase in uninsured ED visits, with varying impacts across hospital types in California.

目的:研究大流行后医疗补助资格重新确定(“解除”)与加利福尼亚州急诊科(ED)付款人组合之间的关系。方法:我们对加州281家普通急症医院的季度急诊科就诊数据(2021-2024)进行了回顾性二次分析,采用中断时间序列分析。结果:在解除期间,与解除前相比,医疗补助急诊科访问量下降了0.37个百分点(pp),未投保急诊科访问量每季度增加0.16个百分点(P < 0.001)。医疗补助下降幅度最大的是投资者所有的医院(0.87个百分点,11.9%)和中型医院(0.47个百分点,7.4%)(P < 0.001)。相比之下,除了小型医院(0.22 pp, 25.8%)之外,农村地区(0.29 pp, 46.7%)和高贫困地区(0.24 pp, 7.7%)的未参保就诊人数增幅最大(P < 0.001)。私人访问立即下降了0.49个百分点(P < 0.001),随后每个季度继续下降0.15个百分点(P < 0.05),显示之前增加的趋势趋于平缓。医疗保险访问增加了0.18 pp每季度(P < 0.001)相对于前解除期间。结论:医疗补助解除与医疗补助急诊科就诊的减少和相应的未投保急诊科就诊的增加有关,在加州不同类型的医院有不同的影响。
{"title":"Unwinding of Medicaid enrollment and increased uninsured emergency department visits in California.","authors":"Nima Khodakarami, Theodoros V Giannouchos, Daniel Marthey, Benjamin Ukert, Joel Segel, Laura Dague","doi":"10.1093/haschl/qxaf238","DOIUrl":"10.1093/haschl/qxaf238","url":null,"abstract":"<p><strong>Objective: </strong>To examine the association between post-pandemic era Medicaid eligibility redeterminations (\"unwinding\") and emergency department (ED) payer mix in California.</p><p><strong>Methods: </strong>We conducted a retrospective secondary analysis of California's quarterly ED visit data (2021-2024) across 281 general acute-care hospitals, using interrupted time-series analysis.</p><p><strong>Results: </strong>During unwinding, Medicaid ED visits declined by 0.37 percentage points (pp) and uninsured ED visits increased by 0.16 pp per quarter (<i>P</i> < .001) relative to the pre-unwinding period. The largest Medicaid declines occurred in investor-owned (0.87 pp, 11.9%) and medium-sized (0.47 pp, 7.4%) hospitals (<i>P</i> < .001). In contrast, the largest increases in uninsured visits occurred among hospitals in rural (0.29 pp, 46.7%) and high-poverty (0.24 pp, 7.7%) areas, in addition to small hospitals (0.22 pp, 25.8%) (<i>P</i> < .001). Private visits saw an immediate decrease of 0.49 pp (<i>P</i> < .001), followed by a continued reduction of 0.15 pp per quarter (<i>P</i> < .05), showing flattening of the previously increasing trend. Medicare visits increased by 0.18 pp per quarter (<i>P</i> < .001) relative to the pre-unwinding period.</p><p><strong>Conclusion: </strong>Medicaid unwinding was associated with a decline in Medicaid ED visits and a corresponding increase in uninsured ED visits, with varying impacts across hospital types in California.</p>","PeriodicalId":94025,"journal":{"name":"Health affairs scholar","volume":"4 1","pages":"qxaf238"},"PeriodicalIF":2.7,"publicationDate":"2025-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12849369/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146088446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Site-neutral payment for routine services could save commercial purchasers and patients billions. 常规服务的现场中立支付可以为商业购买者和患者节省数十亿美元。
IF 2.7 Pub Date : 2025-12-19 eCollection Date: 2025-12-01 DOI: 10.1093/haschl/qxaf241
Roslyn C Murray, Haroon Janjua, Christopher M Whaley

Introduction: Medicare and commercial payers pay more for services delivered in hospital outpatient departments than in physicians' offices or ambulatory surgery centers. These "site-of-care" payment differentials contribute to rising health care spending and drive hospital acquisition of physician practices. Because many non-hospital settings can provide equivalent or higher-quality care at lower costs, site-neutral payment has gained traction in Medicare, with the potential to save patients and taxpayers billions. A growing number of states are exploring similar policies in the commercial market by capping payments for routine services at a percentage of the Medicare payment in non-hospital settings. The impact of such policies for commercial purchasers and patients has not yet been modeled.

Methods: This study uses 2022 commercial claims data from the Health Care Cost Institute and estimates potential savings by capping prices for 2561 routine services (Current Procedural Terminology codes) at 150% of the Medicare payment in hospital, office, and ambulatory surgery center settings.

Results: Site-neutral payment for commercial purchasers and patients could save $10.8 billion across 48 states and Washington, D.C. State level aggregate hospital operating margins would decline modestly.

Conclusion: Site-neutral policies could yield substantial savings but require ongoing monitoring for unintended effects.

简介:医疗保险和商业支付者支付更多的服务提供在医院门诊部门比在医生的办公室或门诊手术中心。这些“医疗现场”的支付差异导致医疗保健支出的增加,并推动医院收购医生的做法。由于许多非医院机构可以以更低的成本提供同等或更高质量的医疗服务,因此地点中立支付在医疗保险中获得了吸引力,有可能为患者和纳税人节省数十亿美元。越来越多的州正在商业市场上探索类似的政策,将常规服务的支付限制在非医院环境下的医疗保险支付的一定比例内。此类政策对商业购买者和患者的影响尚未建立模型。方法:本研究使用来自卫生保健成本研究所的2022年商业索赔数据,并估计通过将医院、办公室和门诊手术中心设置的2561项常规服务(现行程序术语代码)的价格限制在医疗保险支付的150%,可能节省的费用。结果:在48个州和华盛顿特区,商业购买者和患者的站点中立支付可以节省108亿美元。结论:地点中立的政策可以产生大量的节省,但需要持续监测意想不到的影响。
{"title":"Site-neutral payment for routine services could save commercial purchasers and patients billions.","authors":"Roslyn C Murray, Haroon Janjua, Christopher M Whaley","doi":"10.1093/haschl/qxaf241","DOIUrl":"10.1093/haschl/qxaf241","url":null,"abstract":"<p><strong>Introduction: </strong>Medicare and commercial payers pay more for services delivered in hospital outpatient departments than in physicians' offices or ambulatory surgery centers. These \"site-of-care\" payment differentials contribute to rising health care spending and drive hospital acquisition of physician practices. Because many non-hospital settings can provide equivalent or higher-quality care at lower costs, site-neutral payment has gained traction in Medicare, with the potential to save patients and taxpayers billions. A growing number of states are exploring similar policies in the commercial market by capping payments for routine services at a percentage of the Medicare payment in non-hospital settings. The impact of such policies for commercial purchasers and patients has not yet been modeled.</p><p><strong>Methods: </strong>This study uses 2022 commercial claims data from the Health Care Cost Institute and estimates potential savings by capping prices for 2561 routine services (Current Procedural Terminology codes) at 150% of the Medicare payment in hospital, office, and ambulatory surgery center settings.</p><p><strong>Results: </strong>Site-neutral payment for commercial purchasers and patients could save $10.8 billion across 48 states and Washington, D.C. State level aggregate hospital operating margins would decline modestly.</p><p><strong>Conclusion: </strong>Site-neutral policies could yield substantial savings but require ongoing monitoring for unintended effects.</p>","PeriodicalId":94025,"journal":{"name":"Health affairs scholar","volume":"3 12","pages":"qxaf241"},"PeriodicalIF":2.7,"publicationDate":"2025-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12757685/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145901960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Few clinicians provide a wide range of contraceptive methods to Medicaid beneficiaries. 很少有临床医生为医疗补助受益人提供广泛的避孕方法。
IF 2.7 Pub Date : 2025-12-19 eCollection Date: 2026-01-01 DOI: 10.1093/haschl/qxaf242
Julia Strasser, Taylor Gorak, Sara Luckenbill, Yoon Hong Park, Qian Luo

Introduction: Access to contraception services is an essential component of reproductive autonomy; however, low-income individuals frequently face barriers to care, including a shortage of providers who both accept Medicaid and offer contraception services.

Methods: We used 2021 Transformed Medicaid Statistical Information System Prescription and Other Service files to identify clinicians who provided contraception (prescription, implant, and/or intrauterine device (IUD)) to Medicaid beneficiaries.

Results: We identified 523 077 primary care and women's health specialty clinicians (obstetrician-gynecologists, family medicine, internal medicine, pediatrics, nurse practitioners, physician assistants, and midwives) who provided care to reproductive aged (15-44 years) female Medicaid beneficiaries for any service; of these, only 181 019 (34.6%) provided at least one contraception method to Medicaid beneficiaries and even fewer 20 160 (3.9%) provided prescriptions (pill, patch, and/or ring), IUDs, and implants. Over half (54%) of US counties had greater or equal numbers of advanced practice clinicians-nurse practitioners, physician assistants, and midwives-prescribing contraception compared with physicians.

Conclusion: Few clinicians provided a wide range of contraception to Medicaid beneficiaries. Advanced practice clinicians are important providers in counties with limited access to physicians. Documenting workforce variation for contraception care has important implications for access, especially as recent policy changes may make contraception less accessible for Medicaid beneficiaries.

引言:获得避孕服务是生殖自主的重要组成部分;然而,低收入人群经常面临护理障碍,包括既接受医疗补助又提供避孕服务的提供者短缺。方法:我们使用2021年转化的医疗补助统计信息系统处方和其他服务文件来识别向医疗补助受益人提供避孕(处方、植入物和/或宫内节育器)的临床医生。结果:我们确定了523 077名初级保健和妇女健康专业临床医生(妇产科医生、家庭医学、内科医生、儿科医生、执业护士、医师助理和助产士),他们为生育年龄(15-44岁)女性医疗补助受益人提供任何服务;其中,只有181819家(34.6%)向医疗补助受益人提供至少一种避孕方法,甚至更少的20160家(3.9%)提供处方(药片、贴片和/或环)、宫内节育器和植入物。超过一半(54%)的美国县有更多或相同数量的高级执业临床医生——执业护士、医师助理和助产士——与医生相比开避孕处方。结论:很少有临床医生为医疗补助受益人提供广泛的避孕措施。高级实践临床医生是重要的提供者在县与有限的医生。记录避孕护理的劳动力差异对获取具有重要意义,特别是最近的政策变化可能使医疗补助受益人更难获得避孕。
{"title":"Few clinicians provide a wide range of contraceptive methods to Medicaid beneficiaries.","authors":"Julia Strasser, Taylor Gorak, Sara Luckenbill, Yoon Hong Park, Qian Luo","doi":"10.1093/haschl/qxaf242","DOIUrl":"10.1093/haschl/qxaf242","url":null,"abstract":"<p><strong>Introduction: </strong>Access to contraception services is an essential component of reproductive autonomy; however, low-income individuals frequently face barriers to care, including a shortage of providers who both accept Medicaid and offer contraception services.</p><p><strong>Methods: </strong>We used 2021 Transformed Medicaid Statistical Information System Prescription and Other Service files to identify clinicians who provided contraception (prescription, implant, and/or intrauterine device (IUD)) to Medicaid beneficiaries.</p><p><strong>Results: </strong>We identified 523 077 primary care and women's health specialty clinicians (obstetrician-gynecologists, family medicine, internal medicine, pediatrics, nurse practitioners, physician assistants, and midwives) who provided care to reproductive aged (15-44 years) female Medicaid beneficiaries for any service; of these, only 181 019 (34.6%) provided at least one contraception method to Medicaid beneficiaries and even fewer 20 160 (3.9%) provided prescriptions (pill, patch, and/or ring), IUDs, and implants. Over half (54%) of US counties had greater or equal numbers of advanced practice clinicians-nurse practitioners, physician assistants, and midwives-prescribing contraception compared with physicians.</p><p><strong>Conclusion: </strong>Few clinicians provided a wide range of contraception to Medicaid beneficiaries. Advanced practice clinicians are important providers in counties with limited access to physicians. Documenting workforce variation for contraception care has important implications for access, especially as recent policy changes may make contraception less accessible for Medicaid beneficiaries.</p>","PeriodicalId":94025,"journal":{"name":"Health affairs scholar","volume":"4 1","pages":"qxaf242"},"PeriodicalIF":2.7,"publicationDate":"2025-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12778328/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145936159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Federal inspection timing, not compliance, associated with nursing home post-disaster outcomes. 联邦检查的时机,而不是依从性,与养老院的灾后结果有关。
IF 2.7 Pub Date : 2025-12-19 eCollection Date: 2026-01-01 DOI: 10.1093/haschl/qxaf244
Natalia Festa, Kelsey Alexovitz, Manali Phadke, John O'Leary, Kendra Davis-Plourde, Emma Zang, Kai Chen, Jill Kelly, David M Dosa, Andrew Cohen, Thomas M Gill
{"title":"Federal inspection timing, not compliance, associated with nursing home post-disaster outcomes.","authors":"Natalia Festa, Kelsey Alexovitz, Manali Phadke, John O'Leary, Kendra Davis-Plourde, Emma Zang, Kai Chen, Jill Kelly, David M Dosa, Andrew Cohen, Thomas M Gill","doi":"10.1093/haschl/qxaf244","DOIUrl":"10.1093/haschl/qxaf244","url":null,"abstract":"","PeriodicalId":94025,"journal":{"name":"Health affairs scholar","volume":"4 1","pages":"qxaf244"},"PeriodicalIF":2.7,"publicationDate":"2025-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12778326/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145936928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serial patent litigation: an emerging strategy to delay entry of generic competition. 系列专利诉讼:延缓仿制药竞争进入的新策略。
IF 2.7 Pub Date : 2025-12-17 eCollection Date: 2025-12-01 DOI: 10.1093/haschl/qxaf240
Timothy Bonis, Aaron S Kesselheim, Sean Tu

The Hatch-Waxman Act of 1984 was designed to accelerate generic drug entry by establishing a framework for resolving patent disputes between brand-name and generic manufacturers. While the Act has facilitated competition and expanded the availability of affordable medicines, brand-name firms have increasingly exploited its procedural structure to delay or deter generic competition through "serial litigation." This strategy involves filing successive, questionable lawsuits, often based on non-innovative continuation patents. Even if the brand ultimately loses, the delays and litigation costs can discourage generic firms from entering the market or compel them to settle on terms that undermine patients' timely access to affordable generics. In the case of Astellas's overactive bladder drug mirabegron (Myrbetriq), after an initial Hatch-Waxman case settled in 2020 with generic entry expected in 2024, Astellas pursued 4 additional lawsuits, each built on new but substantively indistinguishable patents. These tactics have delayed broad competition, leaving only 2 firms to launch in 2024 under the threat of massive damages. Similar patterns are observed with other drugs, including bimatoprost (Latisse), aflibercept (Eylea), and tasimelteon (Hetlioz).

1984年的哈奇-韦克斯曼法案(Hatch-Waxman Act)旨在通过建立解决品牌和仿制药制造商之间专利纠纷的框架,加速仿制药的进入。虽然该法案促进了竞争,扩大了可负担药品的可获得性,但品牌公司越来越多地利用其程序结构,通过“系列诉讼”来推迟或阻止仿制药竞争。这种策略包括提出连续的、有问题的诉讼,通常基于非创新性的延续专利。即使品牌最终失败,延迟和诉讼成本也会阻碍仿制药公司进入市场,或者迫使他们达成损害患者及时获得可负担的仿制药的条款。在安斯泰来过度活跃的膀胱药物mirabegron (Myrbetriq)的案例中,在最初的哈奇-韦克斯曼(Hatch-Waxman)案于2020年达成和解,预计将于2024年进入仿制药市场后,安斯泰来又提起了4起诉讼,每一起诉讼都是基于新的、但实质上难以区分的专利。这些策略推迟了广泛的竞争,在巨额损失的威胁下,2024年只有两家公司上市。在其他药物中也观察到类似的模式,包括比马前列素(Latisse)、阿非利赛普(Eylea)和塔西美雄(Hetlioz)。
{"title":"Serial patent litigation: an emerging strategy to delay entry of generic competition.","authors":"Timothy Bonis, Aaron S Kesselheim, Sean Tu","doi":"10.1093/haschl/qxaf240","DOIUrl":"10.1093/haschl/qxaf240","url":null,"abstract":"<p><p>The Hatch-Waxman Act of 1984 was designed to accelerate generic drug entry by establishing a framework for resolving patent disputes between brand-name and generic manufacturers. While the Act has facilitated competition and expanded the availability of affordable medicines, brand-name firms have increasingly exploited its procedural structure to delay or deter generic competition through \"serial litigation.\" This strategy involves filing successive, questionable lawsuits, often based on non-innovative continuation patents. Even if the brand ultimately loses, the delays and litigation costs can discourage generic firms from entering the market or compel them to settle on terms that undermine patients' timely access to affordable generics. In the case of Astellas's overactive bladder drug mirabegron (Myrbetriq), after an initial Hatch-Waxman case settled in 2020 with generic entry expected in 2024, Astellas pursued 4 additional lawsuits, each built on new but substantively indistinguishable patents. These tactics have delayed broad competition, leaving only 2 firms to launch in 2024 under the threat of massive damages. Similar patterns are observed with other drugs, including bimatoprost (Latisse), aflibercept (Eylea), and tasimelteon (Hetlioz).</p>","PeriodicalId":94025,"journal":{"name":"Health affairs scholar","volume":"3 12","pages":"qxaf240"},"PeriodicalIF":2.7,"publicationDate":"2025-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12757684/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145901991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
"Disability data: a case study in research limitation transparency": a response. “残疾数据:研究限制透明度的案例研究”:回应。
IF 2.7 Pub Date : 2025-12-11 eCollection Date: 2025-12-01 DOI: 10.1093/haschl/qxaf235
Sophie Mitra
{"title":"\"Disability data: a case study in research limitation transparency\": a response.","authors":"Sophie Mitra","doi":"10.1093/haschl/qxaf235","DOIUrl":"10.1093/haschl/qxaf235","url":null,"abstract":"","PeriodicalId":94025,"journal":{"name":"Health affairs scholar","volume":"3 12","pages":"qxaf235"},"PeriodicalIF":2.7,"publicationDate":"2025-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12742716/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145852045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hospital finances following Connecticut's ban on outpatient facility fees. 康涅狄格禁止门诊收费后,医院的财务状况。
IF 2.7 Pub Date : 2025-12-11 eCollection Date: 2025-12-01 DOI: 10.1093/haschl/qxaf237
Robert Tyler Braun, Rahul Joseph Fernandez, Rachel Swindle, Christine H Monahan, Dunc Williams

Introduction: In 2017, Connecticut prohibited hospitals from billing "facility fees" for certain services delivered off their main campuses.

Methods: Using Hospital Medicare Cost Reports and the National Academy for State Health Policy Hospital Cost Data (2011-2022), we applied a difference-in-differences model within an event study framework to compare hospital financial outcomes between Connecticut hospitals and matched control hospitals nationwide.

Results: Unadjusted trends suggest small declines in operating margins and outpatient-to-total charges after the ban, alongside an increase in inpatient-to-total charges. In adjusted analyses, operating margins and inpatient-to-total charges did not change significantly, while outpatient-to-total charges declined significantly by 6.91%.

Conclusion: Given the small sample and limited precision, a policy effect cannot be ruled out for several outcomes. Future research evaluating the long-term sustainability and impacts on hospital financials, access, and care quality are warranted.

导语:2017年,康涅狄格州禁止医院为其主校区提供的某些服务收取“设施费”。方法:使用医院医疗保险成本报告和国家卫生政策研究院医院成本数据(2011-2022年),我们在事件研究框架内应用差异中的差异模型来比较康涅狄格州医院和全国匹配对照医院之间的医院财务结果。结果:未经调整的趋势表明,禁令后营业利润率和门诊总收费略有下降,同时住院总收费有所增加。在调整后的分析中,营业利润率和住院总收费没有显著变化,而门诊总收费显著下降了6.91%。结论:由于样本量小,精度有限,不能排除政策对若干结果的影响。未来的研究评估长期可持续性和对医院财务,获取和护理质量的影响是必要的。
{"title":"Hospital finances following Connecticut's ban on outpatient facility fees.","authors":"Robert Tyler Braun, Rahul Joseph Fernandez, Rachel Swindle, Christine H Monahan, Dunc Williams","doi":"10.1093/haschl/qxaf237","DOIUrl":"10.1093/haschl/qxaf237","url":null,"abstract":"<p><strong>Introduction: </strong>In 2017, Connecticut prohibited hospitals from billing \"facility fees\" for certain services delivered off their main campuses.</p><p><strong>Methods: </strong>Using Hospital Medicare Cost Reports and the National Academy for State Health Policy Hospital Cost Data (2011-2022), we applied a difference-in-differences model within an event study framework to compare hospital financial outcomes between Connecticut hospitals and matched control hospitals nationwide.</p><p><strong>Results: </strong>Unadjusted trends suggest small declines in operating margins and outpatient-to-total charges after the ban, alongside an increase in inpatient-to-total charges. In adjusted analyses, operating margins and inpatient-to-total charges did not change significantly, while outpatient-to-total charges declined significantly by 6.91%.</p><p><strong>Conclusion: </strong>Given the small sample and limited precision, a policy effect cannot be ruled out for several outcomes. Future research evaluating the long-term sustainability and impacts on hospital financials, access, and care quality are warranted.</p>","PeriodicalId":94025,"journal":{"name":"Health affairs scholar","volume":"3 12","pages":"qxaf237"},"PeriodicalIF":2.7,"publicationDate":"2025-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12757583/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145901963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reply to the Letter to the Editor by Mitra on Disability data: a case study in research limitation transparency. 回复Mitra关于残疾数据的致编辑信:研究限制透明度的案例研究。
IF 2.7 Pub Date : 2025-12-11 eCollection Date: 2025-12-01 DOI: 10.1093/haschl/qxaf236
Scott D Landes, Bonnielin K Swenor, Jean P Hall, Anjali J Forber-Pratt
{"title":"Reply to the Letter to the Editor by Mitra on Disability data: a case study in research limitation transparency.","authors":"Scott D Landes, Bonnielin K Swenor, Jean P Hall, Anjali J Forber-Pratt","doi":"10.1093/haschl/qxaf236","DOIUrl":"10.1093/haschl/qxaf236","url":null,"abstract":"","PeriodicalId":94025,"journal":{"name":"Health affairs scholar","volume":"3 12","pages":"qxaf236"},"PeriodicalIF":2.7,"publicationDate":"2025-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12742715/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145852069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fewer screens, greater needs: housing insecurity and healthcare costs for transgender patients in a safety-net system. 筛查更少,需求更大:安全网系统中跨性别患者的住房不安全和医疗费用。
IF 2.7 Pub Date : 2025-12-05 eCollection Date: 2026-01-01 DOI: 10.1093/haschl/qxaf226
Aaron S Breslow, Gray Babbs, Elizabeth Cavic, Iby Thomas, Isabella Gibaldi, Ana M Progovac, Arjee Restar, Ginette M Sims, Jonathan Alpert, Benjamin Lê Cook, Kevin P Fiori, Samantha Levano, Earle C Chambers

Introduction: Routine screening for health-related social needs (HRSNs) is inconsistent, creating disparities in who gets identified and supported. Transgender patients, already facing structural stigma, may be especially affected.

Methods: We analyzed electronic health records from a large urban safety-net system (2018-2023). We identified 2639 transgender patients with at least one outpatient visit and created a ∼11:1 comparison cohort of 23 944 cisgender patients. Overall, 7.5% (n = 1997) completed a Social Needs Questionnaire (SNQ), including 1840 cisgender and 157 transgender patients. We compared screening rates using chi-square tests and assessed adjusted odds for HRSN with logistic regression.

Results: Transgender patients were screened less often than cisgender patients (5.9% vs 7.7%, P = 0.001). Among those screened, they had more than twice the odds of housing instability, poor-quality housing, and healthcare costs. Odds for interpersonal violence were th3ree times higher. Findings were consistent in sensitivity analyses adjusting for age, insurance, and neighborhood.

Conclusion: Transgender patients were underscreened yet faced greater HRSNs. Standardized screening and expanded supports are critical to support transgender communities.

导论:与健康相关的社会需求(HRSNs)的常规筛查不一致,造成了谁得到识别和支持的差异。已经面临结构性污名的跨性别患者可能会受到特别的影响。方法:我们分析了来自大型城市安全网系统(2018-2023)的电子健康记录。我们确定了2639名至少有一次门诊就诊的跨性别患者,并创建了23944名顺性别患者的~ 11:1比较队列。总体而言,7.5% (n = 1997)完成了社会需求问卷(SNQ),其中包括1840名顺性别患者和157名跨性别患者。我们使用卡方检验比较筛查率,并使用逻辑回归评估HRSN的调整几率。结果:变性患者的筛查率低于顺性患者(5.9% vs 7.7%, P = 0.001)。在接受筛查的人群中,他们住房不稳定、住房质量差、医疗费用高的几率是普通人的两倍多。发生人际暴力的几率要高出3倍。在调整了年龄、保险和邻里关系的敏感性分析中,结果是一致的。结论:变性患者筛查不足,但HRSNs较高。标准化筛查和扩大支持对于支持跨性别社区至关重要。
{"title":"Fewer screens, greater needs: housing insecurity and healthcare costs for transgender patients in a safety-net system.","authors":"Aaron S Breslow, Gray Babbs, Elizabeth Cavic, Iby Thomas, Isabella Gibaldi, Ana M Progovac, Arjee Restar, Ginette M Sims, Jonathan Alpert, Benjamin Lê Cook, Kevin P Fiori, Samantha Levano, Earle C Chambers","doi":"10.1093/haschl/qxaf226","DOIUrl":"10.1093/haschl/qxaf226","url":null,"abstract":"<p><strong>Introduction: </strong>Routine screening for health-related social needs (HRSNs) is inconsistent, creating disparities in who gets identified and supported. Transgender patients, already facing structural stigma, may be especially affected.</p><p><strong>Methods: </strong>We analyzed electronic health records from a large urban safety-net system (2018-2023). We identified 2639 transgender patients with at least one outpatient visit and created a ∼11:1 comparison cohort of 23 944 cisgender patients. Overall, 7.5% (<i>n</i> = 1997) completed a Social Needs Questionnaire (SNQ), including 1840 cisgender and 157 transgender patients. We compared screening rates using chi-square tests and assessed adjusted odds for HRSN with logistic regression.</p><p><strong>Results: </strong>Transgender patients were screened less often than cisgender patients (5.9% vs 7.7%, <i>P</i> = 0.001). Among those screened, they had more than twice the odds of housing instability, poor-quality housing, and healthcare costs. Odds for interpersonal violence were th3ree times higher. Findings were consistent in sensitivity analyses adjusting for age, insurance, and neighborhood.</p><p><strong>Conclusion: </strong>Transgender patients were underscreened yet faced greater HRSNs. Standardized screening and expanded supports are critical to support transgender communities.</p>","PeriodicalId":94025,"journal":{"name":"Health affairs scholar","volume":"4 1","pages":"qxaf226"},"PeriodicalIF":2.7,"publicationDate":"2025-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12849370/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146088450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Health affairs scholar
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1