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Detection of Viruses and development of new treatments: Insights into Antibody-Antigen Interactions and Multifunctional Lab-On-Particle for SARS CoV-2 病毒检测和新疗法的发展:SARS CoV-2抗体-抗原相互作用和多功能颗粒实验室的见解
Pub Date : 2021-12-29 DOI: 10.33696/nanotechnol.2.022
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引用次数: 3
Colorful Conducting Polymer Nanocomposites Brighten up Silicon Solar Cells 彩色导电聚合物纳米复合材料照亮硅太阳能电池
Pub Date : 2021-12-29 DOI: 10.33696/nanotechnol.2.024
Deying Luo, Lei-Ming Yu, Zhenghong Lu
Deying Luo1, Lei-Ming Yu2, Zheng-Hong Lu1,3* 1Department of Materials Science and Engineering, University of Toronto, Toronto, Ontario, M5G 3E4, Canada 2Henan Key Laboratory of Photovoltaic Materials, School of Physics, Henan Normal University, Xinxiang, 453007, China 3Department of Physics, Center for Optoelectronics Engineering Research, Yunnan University, Kunming, 650091, PR China *Correspondence should be addressed to Zheng-Hong Lu; zhenghong.lu@utoronto.ca
罗德英1,余雷明2,鲁政红1,3* 1多伦多大学材料科学与工程系,加拿大安大略省多伦多M5G 3E4 2河南师范大学物理学院河南省光伏材料重点实验室,新乡453007 3云南大学光电子工程研究中心物理系,昆明650091 *通信地址:陆政红;zhenghong.lu@utoronto.ca
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引用次数: 0
Nanotechnology for Water Purification – Current Trends and Challenges 纳米技术用于水净化-目前的趋势和挑战
Pub Date : 2021-12-29 DOI: 10.33696/nanotechnol.2.025
M. Ajith, Paulraj Rajamani
Environmental pollution is a significant concern in both developing and developed countries. The pollution load in the environment accumulates as a result of anthropogenic activity [1]. Both organic and inorganic contaminants are hazardous to living things, and their incidence and persistence have risen dramatically in current years. Human activities, in certain ways, are straining oceans, rivers, and other inland waterways to the point that their quality is substantially damaged. Toxic chemicals such as heavy metals, pesticides, endocrine disruptors, pharmaceutical chemicals, polyaromatic hydrocarbons, organic and inorganic solvents, pathogens and other pollutants reach water bodies, dissolve in them, drift in the water or sediment on the bed, follow-on water contamination [2]. Various approaches have been used to improve the quality of naturally available water to a quality appropriate for human use [3]. The use of cutting-edge nanotechnology in traditional engineering lays the door for practical advancements in innovative decontamination technology in this context.
环境污染在发展中国家和发达国家都是一个重大问题。由于人类活动,环境中的污染负荷不断累积[1]。有机和无机污染物对生物都是有害的,近年来它们的发生率和持久性急剧上升。在某些方面,人类活动正在使海洋、河流和其他内陆水道的水质受到严重破坏。有毒化学物质如重金属、农药、内分泌干扰物、医药化学物质、多芳烃、有机和无机溶剂、病原体等污染物到达水体,溶解在水体中,随水体漂移或沉积在河床上,引起水体污染[2]。人们采用了各种方法来改善自然可用水的质量,使其适合人类使用[3]。在这种情况下,在传统工程中使用尖端纳米技术为创新净化技术的实际进步奠定了基础。
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引用次数: 2
Folic acid-chitosan nanomaterials for delivery of dietary polyphenols 叶酸-壳聚糖纳米材料递送膳食多酚
Pub Date : 2021-12-29 DOI: 10.33696/nanotechnol.2.021
P. Chanphai, H. Tajmir-Riahi
The encapsulation of antioxidant resveratrol, genistein, and curcumin by folic acid-chitosan nanoparticles was studied in aqueous solution, using multiple spectroscopic methods, TEM images and modeling. Structural analysis showed that polyphenol bindings are via hydrophilic, hydrophobic, and H-bonding contacts with resveratrol forming more stable conjugates. As chitosan size increased, the binding efficacy and stability of polyphenol-polymer adducts were increased. Polyphenol binding induced major alterations of chitosan morphology. Folic acid-chitosan nanoparticles are capable of delivering polyphenols in vitro.
采用多光谱法、透射电镜和模型研究了叶酸-壳聚糖纳米颗粒对抗氧化剂白藜芦醇、染料木素和姜黄素的包封作用。结构分析表明,多酚通过亲水性、疏水性和氢键与白藜芦醇结合形成更稳定的偶联物。壳聚糖粒径越大,多酚-聚合物加合物的结合效率和稳定性越高。多酚结合诱导壳聚糖形态发生重大变化。叶酸-壳聚糖纳米颗粒具有体外传递多酚的能力。
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引用次数: 0
Using Intralipid to Improve Delivery of Anti-Cancer Nanodrugs: Effects on RES Clearance and Toxi city, EPR, and Immune Modulation 使用脂质内改善抗癌纳米药物的递送:对RES清除和Toxi, EPR和免疫调节的影响
Pub Date : 2021-12-29 DOI: 10.33696/nanotechnol.2.023
Li Liu, Chien Ho
Encapsulation of therapeutic molecules (e.g., small molecule inhibitors, mRNA, siRNA, aptamers, etc.) into nanomaterials can improve the solubility and blood circulation of the drugs, alter their biodistribution, decrease their toxicities, overcome drug resistance, and facilitate their entry into target cells [1]. The development of anti-cancer nanodrugs has been the focus of intense study for decades. Several anti-cancer nanodrugs have been approved for clinical use all over the world [2]. These have contributed greatly to a lower death rate from some cancers, and thus are widely used. However, an extensive analysis of anti-cancer nanodrugs found an extremely low efficiency of delivery to the tumor, i.e., less than 1% [2]. This is obviously very wasteful and contributes greatly to the increasing cost of health care [1]. To date, most nanodrugs have been focused on cancer research, but the techniques have been translated for many other applications, e.g., vaccines, cardiovascular disease, and neuropathy disease [3-6].
将治疗性分子(如小分子抑制剂、mRNA、siRNA、适体等)包封在纳米材料中,可以改善药物的溶解度和血液循环,改变药物的生物分布,降低药物的毒性,克服耐药性,促进药物进入靶细胞[1]。几十年来,纳米抗癌药物的开发一直是人们关注的焦点。几种抗癌纳米药物已经在世界范围内被批准用于临床[2]。这大大降低了某些癌症的死亡率,因此被广泛使用。然而,对抗癌纳米药物的广泛分析发现,其向肿瘤的递送效率极低,即不到1%[2]。这显然是非常浪费的,并且极大地增加了医疗保健成本[1]。迄今为止,大多数纳米药物都集中在癌症研究上,但这些技术已经被转化为许多其他应用,例如疫苗、心血管疾病和神经病变疾病[3-6]。
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引用次数: 1
Emerging Nanogenerators for Rehabilitation Monitoring and Information Interaction 用于康复监测和信息交互的新兴纳米发电机
Pub Date : 2021-01-01 DOI: 10.33696/nanotechnol.2.017
Bojing Shi, Zhuo Liu, Ouyang Han, Yubo Fan
Soft wearable devices with flexibility and stretchability attract thousands of researchers around the world. These devices can be used in health monitoring, intelligent robotic and rehabilitation training system. Emerging nanogenerators (NGs) have been studied extensively for soft wearable devices due to the advantages of easy fabrication, cost-effective, self-powered and high sensitivity in response to mechanics stimulus. Recently, the scientists have developed a flexible and stretchable nanogenerator for rehabilitation monitoring and information interaction, which is called FSDM-NG and emphasized in this commentary. The piezoelectric and triboelectric effects of the FSDM-NG have been utilized for different functions, showing some interesting and useful results to be acted as a self-powered limb motion sensor and an interface of information interaction. The purpose of the commentary is to discuss the characteristics and perspectives of NGs as self-powered wearable sensors and information interaction devices in biomedical field.
具有柔性和可拉伸性的柔软可穿戴设备吸引了世界各地成千上万的研究人员。这些设备可用于健康监测、智能机器人和康复训练系统。新兴的纳米发电机(NGs)由于其易于制造、成本低廉、自供电和对力学刺激的高灵敏度等优点,在软可穿戴设备中得到了广泛的研究。最近,科学家们开发了一种用于康复监测和信息交互的柔性和可拉伸纳米发电机,称为FSDM-NG,并在这篇评论中强调了这一点。FSDM-NG的压电和摩擦电效应已被用于不同的功能,显示出一些有趣和有用的结果,可以作为自供电肢体运动传感器和信息交互接口。这篇评论的目的是讨论ngg作为自供电可穿戴传感器和信息交互设备在生物医学领域的特点和前景。
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引用次数: 0
Green Nanotechnology: The Influence of Intermolecular and Supramolecular Interactions 绿色纳米技术:分子间和超分子相互作用的影响
Pub Date : 2020-12-31 DOI: 10.33696/NANOTECHNOL.1.013
Otávio Augusto Leitão dos Santos, B. P. Backx
104 In the last decade, the study of nanometer-scale particles has grown exponentially worldwide. This growth is due to the broad field of nanostructures applications, which, due to their dimensions in nanometric sizes, have new properties not found in micro and macro scale. These properties result from the increase in the ratio between the surface area and volume, and the nanostructures’ size directly influences these [1]. Tolerance to temperature, variety of colors, changes in chemical reactivity, efficiency in action against microorganisms, and electrical conductivity are differentiating factors. [2].
104 .在过去的十年中,世界范围内对纳米级粒子的研究呈指数级增长。这种增长是由于纳米结构应用的广泛领域,由于它们的尺寸在纳米尺度上,具有微观和宏观尺度上没有的新特性。这些特性是由于表面积和体积之比的增加,而纳米结构的尺寸直接影响这些特性[1]。对温度的耐受性、颜色的多样性、化学反应性的变化、对微生物的作用效率和电导率是区分因素。[2].
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引用次数: 2
Current Progress in Vanadium Oxide Nanostructures and Its Composites as Supercapacitor Electrodes 纳米氧化钒及其复合材料作为超级电容器电极的研究进展
Pub Date : 2020-09-25 DOI: 10.33696/NANOTECHNOL.1.012
R. Basu, S. Dhara
In recent years, vanadium oxides have gained immense attention in the field of energy storage devices due to their low-cost, layered structure and multi-valency despite their limited electrical conductivity and lower structural stability. In this brief review, we have tried to focus on electrochemical properties of the stoichiometric vanadium oxides along with VO_x composites. The morphology engineering, doping with heteroatom and formation of composites with carbon-based materials and/or conducting polymers in enhancing the supercapacitive performances of the vanadium oxides are discussed in details. Finally, the potentiality and challenges of vanadium oxides nanocomposites for supercapacitor applications are discussed.
近年来,钒氧化物虽然电导率有限,结构稳定性较低,但由于其低成本、层状结构和多价性,在储能器件领域受到了广泛的关注。在这篇简短的综述中,我们试图把重点放在化学计量钒氧化物和VO_x复合材料的电化学性能上。详细讨论了形态工程、杂原子掺杂、碳基材料和/或导电聚合物复合等提高钒氧化物超电容性能的方法。最后,讨论了氧化钒纳米复合材料在超级电容器中的应用潜力和面临的挑战。
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引用次数: 5
Quantifying Respiratory Airborne Particle Dispersion Control Through Improvised Reusable Masks 通过简易可重复使用口罩量化呼吸空气颗粒扩散控制
Pub Date : 2020-07-14 DOI: 10.1101/2020.07.12.20152157
N. J. Edwards, Rebecca Widrick, R. Potember, Mike Gerschefske
Objective: To determine the effectiveness of non-medical grade washable masks or face coverings in controlling airborne dispersion from exhalation (both droplet and aerosol), and to aid in establishing public health strategies on the wearing of masks to reduce COVID-19 transmission. Design: This comparative effectiveness study using an exhalation simulator to conduct 94 experiment runs with combinations of 8 different fabrics, 5 mask designs, and airflows for both talking and coughing. Setting: Non-airtight fume hood and multiple laser scattering particle sensors. Participants: No human participants. Exposure: 10% NaCl nebulized solution delivered by an exhalation simulator through various masks and fabrics with exhalation airflows representative of "coughing" and "talking or singing." Main Outcomes and Measures: The primary outcome was reduction in aerosol dispersion velocity, quantity of particles, and change in dispersion direction. Measurements used in this study included peak expiratory flow (PEF), aerosol velocity, concentration area under curve (AUC), and two novel metrics of expiratory flow dispersion factor (EDF) and filtration efficiency indicator (FEI). Results: Three-way multivariate analysis of variance establishes that factors of fabric, mask design, and exhalation breath level have a statistically significant effect on changing direction, reducing velocity or concentration (Fabric: P = < .001, Wilks' {Lambda} = .000; Mask design: P = < .001, Wilks' {Lambda} = .000; Breath level: P = < .001, Wilks' {Lambda} = .004). There were also statistically significant interaction effects between combinations of all primary factors. Conclusions and Relevance: The application of facial coverings or masks can significantly reduce the airborne dispersion of aerosolized particles from exhalation. The results show that wearing of non-medical grade washable masks or face coverings can help increase the effectiveness of non-pharmaceutical interventions (NPI) especially where infectious contaminants may exist in shared air spaces. However, the effectiveness varies greatly between the specific fabrics and mask designs used.
目的:确定非医用级可洗口罩或面罩控制空气传播(飞沫和气溶胶)的有效性,并有助于制定佩戴口罩的公共卫生策略,以减少COVID-19的传播。设计:本比较效果研究使用呼气模拟器进行94次实验,使用8种不同面料,5种口罩设计,以及说话和咳嗽的气流组合。设置:非密闭通风柜和多个激光散射粒子传感器。参与者:没有人类参与者。暴露:10% NaCl雾化溶液由呼气模拟器通过各种口罩和织物输送,呼气气流代表“咳嗽”和“说话或唱歌”。主要观察指标:主要观察指标为气溶胶扩散速度、颗粒数量的减少和扩散方向的改变。本研究使用的测量方法包括呼气流量峰(PEF)、气溶胶速度、曲线下浓度面积(AUC),以及两个新的呼气流量分散因子(EDF)和过滤效率指标(FEI)。结果:三因素方差分析表明,织物、口罩设计和呼气水平对改变方向、降低速度或浓度有统计学显著影响(织物:P = < 0.001, Wilks' {Lambda} = .000;口罩设计:P = < .001, Wilks' {Lambda} = .000;呼吸水平:P = < 0.001, Wilks' {Lambda} = 0.004)。所有主要因素组合之间也存在统计学上显著的相互作用效应。结论与意义:面罩或面罩的使用可显著减少空气中气溶胶颗粒的扩散。结果表明,佩戴非医用级可洗口罩或面罩有助于提高非药物干预措施(NPI)的有效性,特别是在共用空气空间中可能存在传染性污染物的情况下。然而,不同面料和口罩设计的效果差别很大。
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引用次数: 3
Structural Characterization of Commercial Graphite and Graphene Materials 商用石墨和石墨烯材料的结构表征
Pub Date : 2020-06-01 DOI: 10.33696/nanotechnol.1.005
I. Low, H. Albetran, Michael Degiorgio
Honeycomb hexagonal carbon atoms in graphite exist as crystalline hexagonal (2H) or rhombohedral (3R) phases. Carbon layers exist in an ABAB sequence in the commonly occurring 2H graphite structure with B layers shifted to a registered position relative to the A layers. The ABCABC stacking sequence in the 3R structure has C and B layers shifted by the same distance relative to the B and A layers, respectively [4]. Although highly ordered/ oriented graphite has a 2H hexagonal structure, a minor fraction of the 3R rhombohedral phase may remain in high-quality samples [5]. The discovery that the special allotrope of carbon, graphene, can be fabricated by using the scotch tape approach to produce a single layer of graphite, and the thinnestand strongest-known material universally, led to an increase in its popularity [6]. Graphene is often termed bi-, tri-, or few-layered (4 to 10 layers). Two-dimensional graphene consists of a sp2-hybridized carbon monolayered sheet network of densely packed rhombohedral-arranged honeycomb hexagonal crystal lattices and contains up to a dozen shells [7,8]. Graphene’s properties make it suitable in a variety of applications, such as batteries, sensors, structural composites, functional inks, electron emission displays, catalyst supports, in the biomedical field, and potentially in other future research fields [1-3,8-16].
石墨中的蜂窝六方碳原子以结晶六方(2H)或菱形(3R)相存在。在常见的2H石墨结构中,碳层以ABAB顺序存在,B层相对于a层移位到一个注册位置。3R结构的ABCABC堆叠序列中,C层和B层相对于B层和A层分别移动了相同的距离[4]。尽管高度有序/取向的石墨具有2H六边形结构,但在高质量的样品中仍可能保留少量的3R菱形相[5]。碳的特殊同素异形体,石墨烯,可以通过使用透明胶带的方法来制造单层石墨,这是普遍已知的最薄、最坚固的材料,这一发现使其越来越受欢迎[6]。石墨烯通常被称为双层、三层或少层(4至10层)。二维石墨烯由sp2杂化碳单层片网络组成,该网络由密集排列的菱形排列的蜂窝状六方晶格组成,并包含多达十二个壳层[7,8]。石墨烯的特性使其适用于各种应用,如电池、传感器、结构复合材料、功能油墨、电子发射显示器、催化剂支撑、生物医学领域,以及潜在的其他未来研究领域[1-3,8-16]。
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引用次数: 15
期刊
Journal of nanotechnology and nanomaterials
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