Resuscitation plus最新文献

{"title":"Terminology Matters: Distinguishing Bystanders from First Responders in Resuscitation Science","authors":"Sergio Cazorla-Calderón , Nino Fijačko , Robert Greif","doi":"10.1016/j.resplu.2025.101201","DOIUrl":"10.1016/j.resplu.2025.101201","url":null,"abstract":"","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"27 ","pages":"Article 101201"},"PeriodicalIF":2.4,"publicationDate":"2025-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145924680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does Out-of-hospital Cardiac Arrest Survival Differ by EMS Agency Type in the U.S.? Insights from the CARES Registry","authors":"Janaki L. Nallamothu ,&nbsp;Saket Girotra ,&nbsp;Kevin F. Kennedy ,&nbsp;Paul S. Chan","doi":"10.1016/j.resplu.2025.101198","DOIUrl":"10.1016/j.resplu.2025.101198","url":null,"abstract":"<div><h3>Background</h3><div>There are limited data on whether out-of-hospital cardiac arrest (OHCA) survival differs by emergency medical service (EMS) agency type in the U.S.</div></div><div><h3>Methods</h3><div>Within the Cardiac Arrest Registry to Enhance Survival, we surveyed participating EMS agencies with ≥20 OHCA annually during 2015-2019. Agencies were categorized as fire-based, private, government-based, or other (including hospital-based). Using hierarchical logistic regression, we computed the risk-standardized survival rate (RSSR) to hospital admission and discharge for each EMS agency and examined for differences in RSSR across agency types.</div></div><div><h3>Results</h3><div>Of 577 eligible EMS agencies, 470 (81.5%) completed the survey. Overall, 40.0% of agencies were fire-based, 35.0% were private, 17.3% were government-based, and 7.7% were other. Mean agency-level RSSR to hospital admission was 27.8% <u>+</u> 3.6% and was highest in fire-based EMS agencies (28.9%) and lowest in agencies that were private or other (26.8%; P&lt;0.001 for comparison across all groups). Mean agency-level RSSR to hospital discharge was 10.1% ± 1.8% and was highest in fire-based agencies (10.3%) and lowest in agencies that were private or other (9.7%; P&lt;0.003 across all groups). Fire-based agencies were more likely to have higher numbers of paramedics, lower annual number of dispatches per paramedic, more hours of OHCA training during orientation, and shorter arrival times on the scene and transport times to the hospital.</div></div><div><h3>Conclusions</h3><div>In the U.S., OHCAs attended by fire-based agencies were associated with modestly higher rates of survival to hospital admission compared to OHCAs attended by other EMS agency types. Several resuscitation practices differed by EMS agency type.</div></div>","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"27 ","pages":"Article 101198"},"PeriodicalIF":2.4,"publicationDate":"2025-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145924678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Influence of an educational program utilizing VAK and Kolb’s learning theories on basic cardiopulmonary resuscitation knowledge and practices among private home nurses in Qatar” [Resuscitation Plus 26 (2025) 101071]","authors":"Mohamed Elsayed Saad Aboudonya ,&nbsp;Hoda Diab Fahmy Ibrahim ,&nbsp;Safaa R. Osman","doi":"10.1016/j.resplu.2025.101188","DOIUrl":"10.1016/j.resplu.2025.101188","url":null,"abstract":"","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"27 ","pages":"Article 101188"},"PeriodicalIF":2.4,"publicationDate":"2025-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145790610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of extreme temperatures on out-of-hospital cardiac arrest cases in Hungary: a national time-series analysis","authors":"Bettina Nagy ,&nbsp;Ádám Pál-Jakab ,&nbsp;Boldizsár Kiss ,&nbsp;Anna Morvai ,&nbsp;Bence Sipos ,&nbsp;György Pápai ,&nbsp;Gábor Csató ,&nbsp;Gábor Orbán ,&nbsp;Nora Boussoussou ,&nbsp;Béla Merkely ,&nbsp;Péter Sótonyi ,&nbsp;András Gerencsér ,&nbsp;Brigitta Szilágyi ,&nbsp;Endre Zima","doi":"10.1016/j.resplu.2025.101194","DOIUrl":"10.1016/j.resplu.2025.101194","url":null,"abstract":"<div><h3>Introduction</h3><div>Out-of-hospital cardiac arrest (OHCA) represents a critical public health challenge, with poor survival. Our objective was to evaluate the association between extreme temperature events and OHCA incidence in Hungary, and to assess the potential influence of additional meteorological factors, including humidity and solar radiation.</div></div><div><h3>Methods</h3><div>We conducted a national time-series analysis of 116,579 adult OHCA cases from November 1, 2018, to December 31, 2023. Using negative binomial regression with cluster-robust standard errors, we estimated associations between daily OHCA counts and extreme temperature events, controlling for day-of-week, seasonality, and long-term trends. “Added-effect” models isolated risk attributable to sustained events while controlling for underlying non-linear temperature-health relationships through natural cubic splines. Distributed lag non-linear models (DLNM) characterized exposure-lag-response patterns over 21 days.</div></div><div><h3>Results</h3><div>The temperature-OHCA relationship exhibited a characteristic U-shape with minimum risk at 19.0°C. Sustained cold spells (≥2 days with daily minimum temperature ≤-9.2°C, 2nd percentile) were associated with the highest risk increase (IRR 1.189; 95% CI: 1.089-1.299; p&lt;0.001). Sustained heatwaves (≥3 days with daily average temperature ≥27.1°C, 95th percentile) also significantly increased risk (IRR 1.110; 95% CI: 1.032-1.195; p=0.005). Single severe cold days (minimum temperature &lt;-10°C) carried an IRR of 1.143 (95% CI: 1.012-1.291; p=0.031). DLNM analysis revealed distinct temporal patterns: heat effects were acute and transient (peak at days 2-4, resolved by day 7), while cold effects were delayed and persistent (emerging at day 3, sustained beyond 14 days).</div></div><div><h3>Conclusion</h3><div>Prolonged extreme temperatures represent independent cardiovascular hazards beyond isolated daily exposures. The immediate impact of heat and the delayed, persistent effect of cold carry important implications for public health preparedness, emergency service planning, and the timing of clinical advisories.</div></div>","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"27 ","pages":"Article 101194"},"PeriodicalIF":2.4,"publicationDate":"2025-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145924820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"VA-ECMO in High-Risk Pulmonary Embolism: Outcomes and Role as Bridge to Recovery","authors":"Shreya Arvind ,&nbsp;Hilary Wagner ,&nbsp;Chia-Ling Kuo ,&nbsp;Kelin Zhong ,&nbsp;Jason Gluck ,&nbsp;Joseph Ingrassia","doi":"10.1016/j.resplu.2025.101196","DOIUrl":"10.1016/j.resplu.2025.101196","url":null,"abstract":"<div><h3>Background</h3><div>High–risk pulmonary embolism (HRPE) with hemodynamic instability or cardiac arrest carries an in–hospital mortality rate of nearly 30%. VA-ECMO can stabilize acute RV failure and serve as a bridge to therapy or recovery. Due to the heterogeneous utilization of VA-ECMO in HRPE, its ideal application is uncertain.</div></div><div><h3>Methods</h3><div>We retrospectively reviewed 28 HRPE patients meeting ESC/AHA criteria treated with VA–ECMO at a tertiary center (2017–2024). Clinical, procedural, and outcome data were analyzed, with comparisons between survivors and non-survivors to hospital discharge.</div></div><div><h3>Results</h3><div>Mean age was 52 years; 57.1% survived to discharge. Cardiac arrest occurred in 78.6%. Patients with cardiac arrest had similar survival to non-arrest patients (p=0.673).</div><div>ECMO was initiated primarily in the catheterization lab (78.6%) and was used similarly between survivors and non-survivors at discharge (p = 0.406). As a bridge to recovery, it was used in 58.3% of non-survivors versus 43.8% of survivors. Mobile ECMO was used in 21.4%, with survival comparable to the overall cohort. Bleeding complications occurred in 82.1% of the patients, most commonly at vascular access sites (65.2%); systemic thrombolysis increased transfusion requirement (p=0.007) but did not significantly affect survival (p=0.673).</div></div><div><h3>Conclusions</h3><div>VA-ECMO achieved a 57.1% survival to discharge, consistent with prior studies. No significant survival differences were found between patients with or without cardiac arrest, pre-ECMO thrombolysis, or mobile versus in-hospital ECMO. Thrombolysis increased bleeding without improving outcomes. Mobile ECMO provided rapid support with comparable survival rates. Half of survivors recovered without adjunctive therapies, highlighting ECMO’s role as a bridge to recovery. Larger studies are needed to optimize protocols.</div></div>","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"27 ","pages":"Article 101196"},"PeriodicalIF":2.4,"publicationDate":"2025-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145924677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploration of ‘generational’ peer-led CPR training in the Australian community using blended learning approaches: A pilot randomised controlled trial","authors":"Jeremy Pallas ,&nbsp;Mark Miller ,&nbsp;Shaun Hicks ,&nbsp;Phillip Newton ,&nbsp;Ginger Chu ,&nbsp;John Paul Smiles ,&nbsp;Michael Zhang","doi":"10.1016/j.resplu.2025.101190","DOIUrl":"10.1016/j.resplu.2025.101190","url":null,"abstract":"<div><h3>Aim</h3><div>A pilot randomised controlled trial to assess the feasibility and relative effectiveness of a community CPR train-the-trainer model using either a traditional face-to-face or blended learning approach (video supported face-to-face training with the provision of a multimodal ‘CPR lesson card’ containing visual prompts and a QR linked training video). A ‘generational’ recruitment strategy was used to evaluate knowledge degradation across a series of peer-led training episodes.</div></div><div><h3>Methods</h3><div>Participants (n = 155) were community volunteers aged 18–85 years with no recent CPR training. Groups were randomised to either face-to-face (control) or blended training (intervention) groups. The first participant in each stream (Generation one) received professional training and subsequently taught the next generation, continuing up to four generations. Progression required passing a simulated cardiac arrest assessment against a critical item checklist including a QCPR score ≥ 50.</div></div><div><h3>Results</h3><div>In total, 115 CPR assessments were conducted (57 intervention, 58 control) following episodes of intergenerational peer-led training. Pass rates were 96.5% (55/57, 95% CI: 87.9-99.6%) in the intervention group and 75.9% (44/58, 95% CI: 62.8-86.1%) in the control group (Fisher’s Exact p = &lt;0.05). The combined pass rate between both groups was 86%, supporting feasibility of peer-led CPR training.</div></div><div><h3>Conclusion</h3><div>Peer-to-peer CPR training in the community is feasible through several generations of knowledge transfer. The use of a simple multimodal training aid appears to enhance performance beyond the first generation and may provide a scalable, cost-effective adjunct to traditional CPR training.</div></div>","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"27 ","pages":"Article 101190"},"PeriodicalIF":2.4,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145924673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility of Public CPR Training Kiosks to Increase Bystander Resuscitation: A Monte Carlo Simulation Study","authors":"Robert Ohle ,&nbsp;David W. Savage ,&nbsp;Danielle Roy ,&nbsp;Krishan Yadav ,&nbsp;Shawn Chabra ,&nbsp;Sarah McIsaac","doi":"10.1016/j.resplu.2025.101189","DOIUrl":"10.1016/j.resplu.2025.101189","url":null,"abstract":"<div><h3>Background</h3><div>Survival after out-of-hospital cardiac arrest (OHCA) depends on immediate bystander cardiopulmonary resuscitation (CPR), yet rates range from 42-70% in Canada. Traditional CPR education faces barriers of access, retention, and scalability. Public CPR kiosks are a novel alternative, but their potential population-level impact is uncertain.</div></div><div><h3>Methods</h3><div>We developed a Monte Carlo and queueing-based simulation model to estimate the effect of CPR kiosks on bystander CPR in Toronto, Canada. The model incorporated venue-specific passer volumes, funnel attrition (approach, engagement, practice, competence), demographic witness likelihood, post-training willingness to act, and skill retention. Outcomes included competent trainees, witness-weighted trainees, additional CPR attempts, change in citywide bystander CPR, lives saved, and cost-effectiveness. We modelled deployment of 30 kiosks across four venue types—mega-volume public spaces (n=6), hospitals (n=8), large commercial venues (n=8), and community sites (n=8)—each with empirically informed passer volumes and engagement probabilities.</div></div><div><h3>Results</h3><div>Median annual throughput per kiosk ranged from 488 competent trainees (95% credible interval [CrI], 94–1550) at small sites (0.5 million passers) to 19,618 (95% CrI, 3706–50,000) at mega-sites (40 million passers). Witness-weighted trainees were highest in hospitals and pharmacies, reflecting more caregivers and seniors. Training increased willingness to act from 40% to 60–80%; this action uplift strongly influenced outcomes. In Toronto, a blended network of 30 kiosks (6 mega, 8 hospital, 8 community, 8 large) increased bystander CPR by 7.5–8.0 percentage points, with a 90–95% probability of meeting or exceeding a 5–point target within one year. This translated to ∼150 additional CPR attempts and 15 lives saved annually. Costs were ∼$10,000 per life saved and ∼$1250 per quality-adjusted life year (QALY).</div></div><div><h3>Conclusions</h3><div>Simulation modeling suggests CPR kiosks can feasibly and cost-effectively increase bystander CPR, with impact shaped by visibility, action willingness, and targeting individuals most likely to witness arrest.</div></div>","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"27 ","pages":"Article 101189"},"PeriodicalIF":2.4,"publicationDate":"2025-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145924816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DISPATCHER-ASSISTED CARDIOPULMONARY RESUSCITATION FOR OUT-OF-HOSPITAL CARDIAC ARREST PATIENTS: A SITE-LEVEL ANALYSIS OF THE PAROS TRIAL","authors":"Fahad Javaid Siddiqui ,&nbsp;Stephanie Fook-Chong ,&nbsp;Nur Shahidah ,&nbsp;David Pflug ,&nbsp;Benjamin Sieu-Hon Leong ,&nbsp;Sang Do Shin ,&nbsp;Hyun Wook Ryoo ,&nbsp;Hyun Ho Ryu ,&nbsp;Chih-Hao Lin ,&nbsp;Chan-Wei Kuo ,&nbsp;Marcus Eng Hock Ong","doi":"10.1016/j.resplu.2025.101193","DOIUrl":"10.1016/j.resplu.2025.101193","url":null,"abstract":"<div><h3>Objectives</h3><div>The study aimed to examine the influence of contextual settings on the complex OHCA intervention outcomes thereby providing evidence to guide managers and policymakers in optimizing implementation strategies. Our secondary analysis of an international multi–site trial examined site–level effectiveness of comprehensive versus basic Dispatcher-Assisted CPR (DACPR) interventions on bystander CPR rates, hypothesizing site-specific variation and declining variability as an early sign.</div></div><div><h3>Methods</h3><div>Using 2009–2018 data from the Pan-Asian Resuscitation Outcomes Study (PAROS), we compared monthly and quarterly trends in BCPR rates at selected PAROS sites before and after the intervention. Interrupted time series analysis was performed using regression of monthly BCPR rates for the pre- and post-intervention periods.</div></div><div><h3>Results</h3><div>Six PAROS sites contributed 37,872 out-of-hospital cardiac arrest (OHCA) cases from January 2009 to June 2018. Comprehensive package sites showed consistent improvement in average monthly BCPR rates, with absolute increases ranging from 4.2 to 30.8 percentage points. Sharper post-intervention increases in DACPR rates were observed, indicated by positive site-wise regression coefficient differences (0.07 to 0.38). However, some sites experienced an initial post-intervention slowdown of the pre-existing trend. The two Basic package sites also improved their BCPR rates by 9.3 and 25.1 percentage points, though the shorter pre-intervention periods limited meaningful interpretation of the rate of change (0.22 &amp; -0.33).</div></div><div><h3>Conclusion</h3><div>Both intervention packages improved BCPR rates, with most sites showing steeper improvements post-intervention. However, variations in timing and magnitude between sites highlight differing levels of system readiness and implementation rigor. Reduced variability has been observed post-intervention.</div></div>","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"27 ","pages":"Article 101193"},"PeriodicalIF":2.4,"publicationDate":"2025-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145924674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inter-rater Reliability of Point-of-Care Ultrasound During Out-of-Hospital Cardiac Arrest: An Ancillary Analysis of the observational prospective ACE Trial","authors":"Mathilde Papin ,&nbsp;Thibaut Markarian ,&nbsp;Quentin Le Bastard ,&nbsp;Christelle Volteau ,&nbsp;Philippe Pes ,&nbsp;Philippe Le Conte ,&nbsp;François Javaudin","doi":"10.1016/j.resplu.2025.101191","DOIUrl":"10.1016/j.resplu.2025.101191","url":null,"abstract":"<div><h3>Background</h3><div>Prognostication in out-of-hospital cardiac arrest (OHCA) remains challenging. While point-of-care ultrasound (POCUS) has demonstrated utility in identifying reversible causes and predicting outcomes, the quality and reliability of echocardiographic assessments in this context remain poorly characterized. This study aimed to evaluate interrater agreement between trained emergency physicians (POCUS operators) and ultrasound experts in assessing cardiac motion on ultrasound during cardiopulmonary resuscitation (CPR).</div></div><div><h3>Methods</h3><div>This study was an ancillary analysis of the ACE trial, a multicenter, prospective, observational study conducted between November 2018 and January 2023, which included 293 patients. A random sample comprising 20% of recorded ultrasound cine loops was included in the present analysis. Two independent experts evaluated the presence of visible cardiac motion. Their assessments were compared with those of the POCUS operator using Cohen’s κ coefficients.</div></div><div><h3>Results</h3><div>A total of 52 POCUS cine loops were collected. The median patient age was 69 years. The presumed etiology of OHCA was cardiac in 61.5% of cases, noncardiac medical in 32.7%, and traumatic in 5.8%. Expert 1 excluded 16 loops (31%) and Expert 2 excluded 9 loops (17%) because of insufficient image quality. The κ coefficients for detection of cardiac motion were 0.26 (95% CI, –0.05 to 0.58) and 0.25 (95% CI, –0.05 to 0.54) for agreement between operators and experts 1 and 2, respectively. Inter-expert agreement was higher, with a κ of 0.75 (95% CI, 0.51 to 0.98). The positive predictive value of cardiac standstill for absence of return of spontaneous circulation (ROSC) did not differ significantly between operators and experts (74.3% vs 65.0% and 72.4%; p = 0.47 and 0.87, respectively).</div></div><div><h3>Conclusion</h3><div>Agreement between emergency physicians and experts regarding POCUS image quality and interpretation of cardiac motion during OHCA was limited. However, this discrepancy did not appear to significantly affect the prognostication of ROSC. Further training and standardization of image acquisition and interpretation criteria may improve POCUS reliability in this setting.</div><div>Trial registration</div><div>This paper is an ancillary study of the ACE trial, registered on ClinicalTrials.gov (Identifier: NCT 03494153) on March 29, 2018.</div></div>","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"27 ","pages":"Article 101191"},"PeriodicalIF":2.4,"publicationDate":"2025-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145924817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of ventilatory parameters reporting in large animal models of cardiac arrest: a scoping review","authors":"Jean-Claude Li ,&nbsp;Nicolas Segond ,&nbsp;Arnaud Lesimple ,&nbsp;Alice Hutin ,&nbsp;Rebecca Goutchtat ,&nbsp;Iann Drennan ,&nbsp;Giuseppe Ristagno ,&nbsp;Guillaume Debaty ,&nbsp;Alain Cariou ,&nbsp;Renaud Tissier ,&nbsp;Jean-Christophe Richard","doi":"10.1016/j.resplu.2025.101185","DOIUrl":"10.1016/j.resplu.2025.101185","url":null,"abstract":"<div><h3>Background</h3><div>Ventilation is a critical determinant of cardiopulmonary resuscitation efficiency. Our goal was to evaluate how ventilatory parameters are reported during cardiopulmonary resuscitation in large animal models of cardiac arrest.</div></div><div><h3>Methods</h3><div>A scoping review was conducted following the PRISMA-ScR guidelines, including studies referenced in Pubmed over the last decade (January 1st, 2015 to July 30th, 2025). The review followed the PCC approach: (P) population: large animal models of cardiac arrest; (C) concept: ventilatory settings and parameters during CPR; (C) context: studies aiming at describing or evaluating mechanical or manual ventilation during CPR in experimental conditions. The reporting of the animal characteristics, ventilatory settings and monitored parameters were extracted and analyzed descriptively.</div></div><div><h3>Results</h3><div>We identified 111 relevant publications. Most of them used porcine models (79 %), with ventricular fibrillation being the most common method of cardiac arrest induction (59 %). Mechanical ventilation was predominant (75 %), with volume and pressure-controlled modes nearly equally represented. The reporting of critical ventilatory settings was inconsistent, with a percentage of appropriate reporting as follows: respiratory rate (88 %), fraction of inspired oxygen (83 %), positive end-expiratory pressure (49 %), tidal volume (83 %, among studies with volume-controlled ventilation), peak inspiratory pressure (92 %, among studies with pressure-controlled ventilation) and inspiratory to expiratory ratio (17 %, among all studies with mechanical ventilation). Reporting of measured ventilatory parameters during CPR was also limited with, e.g., EtCO₂ reported in 41 % of the studies and arterial blood gases sampled and reported in 50 % of the studies.</div></div><div><h3>Conclusions</h3><div>This scoping review evidenced substantial variability and frequent omissions in the reporting of ventilatory settings and monitoring in large animal CPR studies. Updated recommendations could be useful to provide specific guidelines of reporting in the field.</div></div>","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"27 ","pages":"Article 101185"},"PeriodicalIF":2.4,"publicationDate":"2025-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145790609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}