Resuscitation plus最新文献

{"title":"Esmolol in persistent ventricular fibrillation/tachycardia with de-emphasised adrenaline – Introducing the REVIVE project","authors":"Thomas Gleeson-Hammerton , Julian Hannah , John Pike , Matthew Taylor , James Raitt , Peter Owen , David B. Sidebottom , Adam Watson , David Jeffery , James Plumb","doi":"10.1016/j.resplu.2024.100842","DOIUrl":"10.1016/j.resplu.2024.100842","url":null,"abstract":"","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"21 ","pages":"Article 100842"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11729003/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142981089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to: Sex-specific health-related quality of life in survivors of cardiac arrest","authors":"Matthew Potter, Neil Magee, Eleni Aliki Nikolopoulou, Uzma Sajjad, Thomas R. Keeble, Marco Mion","doi":"10.1016/j.resplu.2024.100852","DOIUrl":"10.1016/j.resplu.2024.100852","url":null,"abstract":"","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"21 ","pages":"Article 100852"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11745946/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143019217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Challenges during cardiac arrest in pregnancy","authors":"Korneel Berteloot,&nbsp;Marc Sabbe","doi":"10.1016/j.resplu.2024.100855","DOIUrl":"10.1016/j.resplu.2024.100855","url":null,"abstract":"<div><div>A 36-year-old woman at 23 weeks and 3 days of gestation experienced a witnessed cardiopulmonary collapse. Bystander cardiopulmonary resuscitation (CPR) was initiated immediately. After advanced life support, she was transferred under mechanical CPR to a hospital for extracorporeal membrane oxygenation (ECMO). There, a delayed perimortem caesarean section (PMCS) was performed. Consideration to initiate ECMO following the PMCS was ultimately discontinued due to extensive intra-abdominal haemorrhage and the elapsed time of over one hour since the collapse. A full body computed tomography (CT) scan following ROSC revealed bilateral pulmonary embolisms and grade 4 liver laceration with active bleeding due to mechanical CPR. Despite the prolonged duration of cardiac arrest (69 min) and significant metabolic derangements, the patient had a favourable recovery and was discharged after 42 days with a good neurological outcome. This case illustrates the challenges of timely perimortem caesarean section in out-of-hospital cardiac arrest, where guidelines recommend performing the procedure within 4 min of maternal collapse. It also highlights the risks associated with mechanical chest compression devices.</div></div>","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"21 ","pages":"Article 100855"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11755073/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143030580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ILCOR World Restart a Heart – Spreading global CPR awareness and empowering communities to save lives since 2018","authors":"N. Rott ,&nbsp;L. Reinsch ,&nbsp;B.W. Böttiger ,&nbsp;A. Lockey","doi":"10.1016/j.resplu.2024.100853","DOIUrl":"10.1016/j.resplu.2024.100853","url":null,"abstract":"<div><div>The International Liaison Committee on Resuscitation (ILCOR) World Restart a Heart (WRAH) Initiative is helping to save countless lives by promoting a culture of preparedness and encouraging widespread lay cardiopulmonary resuscitation (CPR) training. In total from 2018 to 2023 at least 12.6 million people were trained, and 570.7 million people were reached, showing a variety of campaigns adapted to countries current situation and their culture. World Restart a Heart success is based on an annual collaboration between nations, organisations and communities, demonstrating its universal relevance and impact. Because of this it is able to adapt to varies different circumstances and presents an accessible and effective solution to a significant global health problem, saving many lives over the years by promoting bystander CPR.</div></div>","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"21 ","pages":"Article 100853"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11757781/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143049357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prehospital critical care beyond advanced life support for out-of-hospital cardiac arrest: A systematic review","authors":"Adam J. Boulton ,&nbsp;Rachel Edwards ,&nbsp;Andrew Gadie ,&nbsp;Daniel Clayton ,&nbsp;Caroline Leech ,&nbsp;Michael A. Smyth ,&nbsp;Terry Brown ,&nbsp;Joyce Yeung ,&nbsp;on behalf of the International Liaison Committee on Resuscitation (ILCOR) Education, Implementation and Team (EIT) taskForce","doi":"10.1016/j.resplu.2024.100803","DOIUrl":"10.1016/j.resplu.2024.100803","url":null,"abstract":"<div><h3>Aim</h3><div>To assess the clinical outcomes of patients with out-of-hospital cardiac arrest attended by prehospital critical care teams compared to non-critical care teams.</div></div><div><h3>Methods</h3><div>This review was prospectively registered with PROSPERO and the eligibility criteria followed a PICOST framework for ILCOR systematic reviews. Prehospital critical care was defined as any provider with enhanced clinical competencies beyond standard advanced life support algorithms and dedicated dispatch to critically ill patients. MEDLINE, Embase and CINAHL databases were searched from inception to 20 April 2024. Risk of bias was assessed using the ROBINS-I tool and the certainty of evidence by the GRADE approach. Meta-analyses of pooled data from studies at moderate risk of bias were performed using a generic inverse-variance with random-effects.</div></div><div><h3>Results</h3><div>The search returned 6,444 results and 17 articles were included, reporting 1,192,158 patients. Three studies reported traumatic patients and one reported paediatric patients. All studies were non-randomised and 15 were at moderate risk of bias. Most studies included prehospital physicians (n = 16). For adult non-traumatic patients, the certainty of evidence was low and prehospital critical care was associated with improved survival to hospital admission (OR 1.95, 95% CI 1.35–2.82), survival to hospital discharge (OR 1.34, 95% CI 1.10–1.63), survival at 30 days (OR 1.56, 95% CI 1.38–1.75), and favourable neurological outcome at 30 days (OR 1.48, 95% CI 1.19–1.84). Prehospital critical care was also associated with improved outcomes for traumatic and paediatric patients and the certainty of evidence was very low.</div></div><div><h3>Conclusion</h3><div>Attendance of prehospital critical care teams to patients with out-of-hospital cardiac arrest is associated with improved outcomes.</div></div>","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"21 ","pages":"Article 100803"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11728073/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142981059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Respiratory metrics of neonatal positive pressure ventilation on different ventilatory rates: A simulation study","authors":"Ming Zhou ,&nbsp;Xiaohong Xi ,&nbsp;Pu Zhao ,&nbsp;Silu Wang ,&nbsp;Fangfang Tao ,&nbsp;Xiaoying Gu ,&nbsp;Po-Yin Cheung ,&nbsp;Jiang-Qin Liu","doi":"10.1016/j.resplu.2024.100860","DOIUrl":"10.1016/j.resplu.2024.100860","url":null,"abstract":"<div><h3>Background</h3><div>Effective ventilation is the core of neonatal resuscitation (NR). T-piece resuscitators (TPR) and self-inflating bags (SIB) are the two most widely utilized resuscitation devices. Nevertheless, limited information is available regarding the respiratory metrics during NR with these devices.</div></div><div><h3>Objectives</h3><div>This study aimed to evaluate the respiratory metrics at different ventilatory rates (VR) using a TPR or SIB during NR training.</div></div><div><h3>Methods</h3><div>An observational, simulation study was conducted during a NR training course. The participants were instructed to perform positive pressure ventilation at predetermined pressures and varying rates using TPR and SIB. They were subsequently grouped into three categories based on their actual VR: 20–40 breaths per minute (bpm) (SlowVR), 40–60 bpm (StdVR), and 60–80 bpm (FastVR). Respiratory metrics were recorded and analyzed using a neonatal active lung model (NALM).</div></div><div><h3>Results</h3><div>Of the 71 participants in the training course, data from 66 were validated by analyzing 198 ventilations. In general, the participants manipulated the TPR slightly slower than the SIB. Notably, the positive end-expiratory pressure (PEEP) detected via TPR in the NALM was substantially higher, whereas the tidal volume (Tv) and minute volume (MV) with TPR were significantly smaller than those with SIB (p &lt; 0.05). A significant decrease in the peak alveolar pressure (palva) was observed with faster TPR ventilation (p &lt; 0.001), whereas no such reduction was observed with SIB (p = 0.103). Additionally, faster VR correlated positively with higher PEEP levels for both TPR (F = 7.543, p = 0.002) and SIB (F = 7.720, p = 0.002) and inversely with smaller Tv for both TPR (F = 19.239, p &lt; 0.001) and SIB (F = 14.937, p &lt; 0.001). However, no significant differences in MV were observed across the different VR for either TPR or SIB (both p &gt; 0.05).</div></div><div><h3>Conclusions</h3><div>Faster VR were inversely associated with smaller Tv but increased PEEP in both devices. Despite the guidelines of NR, VR exceeding 60 bpm with TPR might sometimes be used, was associated with excessive PEEP in TPR, which may not be a safe in clinical practice. The effect of varying VR on MV was relatively minor for both TPR and SIB.</div></div>","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"21 ","pages":"Article 100860"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11780169/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143070613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association between the type of bystander and survival after an out-of-hospital cardiac arrest: A French nationwide study","authors":"Hizia Benkerrou ,&nbsp;Marguerite Lockhart ,&nbsp;Matthieu Heidet ,&nbsp;Ramy Azzouz ,&nbsp;Christian Vilhelm ,&nbsp;Hervé Hubert ,&nbsp;Morgan Recher ,&nbsp;Valentine Baert ,&nbsp;GR-RéAC","doi":"10.1016/j.resplu.2024.100858","DOIUrl":"10.1016/j.resplu.2024.100858","url":null,"abstract":"<div><h3>Background</h3><div>Early bystander interventions are associated with more favorable outcomes after out-of-hospital cardiac arrest (OHCA). The objective of the present study was to determine whether the type of bystander-patient relationship was associated with survival and neurological outcomes after OHCA in France.</div></div><div><h3>Methods</h3><div>We analyzed data registered in the French National Cardiac Arrest Registry (RéAC) between July 1st, 2011, and April 30th, 2023. The study population comprised bystander-attended cases of OHCA managed by the emergency medical services. Bystanders were categorized as family members, other laypersons, off-duty professional first responders, or off-duty healthcare professionals. The primary outcome was 30-day survival with a favorable neurological outcome (Cerebral Performance Category 1 or 2). The secondary outcomes included the bystander cardiopulmonary resuscitation (CPR) initiation rate, return of spontaneous circulation, and survival upon admission to the hospital. Our statistical analyses were based on bivariate and multivariable logistic regressions analyses.</div></div><div><h3>Results</h3><div>Among the 89,861 OHCA cases analyzed, family members constituted the largest group of bystanders (69.2%). Compared with non-family-member bystanders, family bystander status was associated with a lower CPR initiation rate, a longer no-flow time, and lower 30-day survival rates. Specifically, cases of OHCA with non-family-member bystanders were 32% more likely to survive with a CPC of 1–2 at day 30 than cases with family member bystanders. Medically trained bystander status (off-duty professional first responders and healthcare professionals) was associated with higher CPR initiation and 30-day survival rates, relative to nontrained laypersons.</div></div><div><h3>Conclusions</h3><div>Survival after an OHCA appears to be associated with the type of bystander. Although family members were the most common bystanders, they were less likely to initiate CPR and less likely to see the OHCA patient survive. Efforts to increase the post-OHCA survival rate should include targeted interventions (such as public education and training programs) that emphasize the importance of early CPR and automated external defibrillator use by family members.</div></div>","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"21 ","pages":"Article 100858"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11780125/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143070624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In situ simulation for cardiopulmonary resuscitation training: A systematic review","authors":"Andrea Cortegiani ,&nbsp;Mariachiara Ippolito ,&nbsp;Cristian Abelairas-Gómez ,&nbsp;Sabine Nabecker ,&nbsp;Alexander Olaussen ,&nbsp;Kasper G. Lauridsen ,&nbsp;Yiqun Lin ,&nbsp;Taylor Sawyer ,&nbsp;Joyce Yeung ,&nbsp;Andrew S. Lockey ,&nbsp;Adam Cheng ,&nbsp;Robert Greif","doi":"10.1016/j.resplu.2024.100863","DOIUrl":"10.1016/j.resplu.2024.100863","url":null,"abstract":"<div><h3>Objectives</h3><div>To evaluate the effectiveness of in situ simulation for cardiopulmonary resuscitation (CPR) training on clinical and educational outcomes.</div></div><div><h3>Methods</h3><div>Randomised controlled trials (RCT) and non-randomised studies evaluating in situ simulation for cardiopulmonary resuscitation CPR training of healthcare workers in any setting compared to traditional training and reporting data on patients’ survival, patients’ outcomes, clinical performance and teamwork in actual or simulated resuscitation and resources needed were included. PubMed, Embase and Cochrane were searches from inception to October 28th 2024 (PROSPERO CRD42024521780). The assessment of risk of bias was done using RoB2 or ROBINS-I and the certainty of evidence was assessed by the GRADE approach. Meta-analysis was not possible due to significant heterogeneity in setting, interventions, control, and outcome definitions. The evidence was summarised according to the Synthesis Without Meta-Analysis (SwiM) reporting guidelines. No funding has been obtained.</div></div><div><h3>Results</h3><div>From 1062 records, 10 articles were included after full-text review (4 RCTs, 6 non-randomised). The risk of bias was judged as high or some concerns for RCTs and critical or serious for non-randomised studies. The certainty of evidence was very low for all the evaluated outcomes mainly due to risk of bias, inconsistency and imprecision. Two non-randomised studies reported data on patient survival, while two other non-randomized studies provided data on the review outcome of ’patient outcomes’, suggesting a potential benefit of in situ simulation or no difference. Four non-randomised studies reported improving or no difference in clinical performance in actual resuscitation. One study reported improved teamwork in actual resuscitation while another reported no difference. Most included studies reported improved clinical performance, teamwork and CPR skill in simulated resuscitation after in situ simulation training vs. traditional training. No study evaluated the resources needed.</div></div><div><h3>Conclusion</h3><div>The heterogenous evidence suggests that in situ simulation should be considered as an option for CPR training. The certainty of evidence is very low and cost-benefit balance is uncertain due to lack of data about resource needed.</div></div>","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"21 ","pages":"Article 100863"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787034/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143082736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Not all shockable initial rhythms have the similar clinical outcome in cardiac arrest victims","authors":"Ali Çoner,&nbsp;Can Ramazan Öncel,&nbsp;Cemal Köseoğlu","doi":"10.1016/j.resplu.2024.100832","DOIUrl":"10.1016/j.resplu.2024.100832","url":null,"abstract":"","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"21 ","pages":"Article 100832"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143098594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Team resuscitation for paediatrics (TRAP); application and validation of a paediatric resuscitation quality instrument in non-simulated resuscitations","authors":"Shannon Flood ,&nbsp;Michelle Alletag ,&nbsp;Beth D’Amico ,&nbsp;Sarah Halstead ,&nbsp;Patrick Mahar ,&nbsp;Laura Rochford ,&nbsp;Geoffrey Markowitz ,&nbsp;Jan Leonard ,&nbsp;Lilliam Ambroggio ,&nbsp;Tara Neubrand","doi":"10.1016/j.resplu.2024.100844","DOIUrl":"10.1016/j.resplu.2024.100844","url":null,"abstract":"<div><h3>Background</h3><div>Resuscitation of paediatric cardiac and respiratory arrest is a high-stakes and low frequency event in the paediatric emergency department. Resuscitation team performance assessment tools have been developed and validated for use in the simulation environment, but no tool currently exists to evaluate clinical performance in non-simulated, live paediatric resuscitations.</div></div><div><h3>Methods</h3><div>This is a validation study assessing inter-rater reliability of a novel assessment tool of clinical performance of non-simulated resuscitations, the Team Resuscitation for Paediatrics tool. Videos of medical resuscitations at a tertiary care paediatric emergency department were collected and analysed over a 6-month period. Four paediatric emergency medicine attending physicians reviewed the videos and scored team performance based on the tool. Percent agreement and Fleiss’ Kappa were calculated in 3 subcategories: team communication, cardiac arrest and respiratory arrest. Percent agreement ranges were established a priori as &gt; 80 % considered good and &lt; 60 % poor.</div></div><div><h3>Results</h3><div>Of 51 resuscitations occurring during the study period, 24 met inclusion criteria. All subcategories demonstrated overall moderate agreement however individual items showed a wide range of agreement. Kappa scores were low on both individual items and overall. Three of four items on the team communication tool met criteria for good agreement, 12/34 items on the cardiac arrest tool met good agreement and 9/27 items on the respiratory arrest tool met good agreement.</div></div><div><h3>Conclusion</h3><div>This study demonstrated that development, application and testing of clinical tools to assess resuscitation team performance of non-simulated, video-recorded resuscitations is feasible, however, the Team Resuscitation for Paediatrics tool did not demonstrate adequate inter-rater reliability suggesting that further tool development may be necessary to better evaluate clinical resuscitation performance.</div></div>","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"21 ","pages":"Article 100844"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11729005/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142981090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}