Objective: Chronic kidney disease (CKD), characterized by progressive renal function loss, often necessitates replacement therapies to prevent mortality, with kidney transplantation being the most effective option. The COVID-19 pandemic profoundly affected healthcare systems, reducing transplant activities and lengthening waiting times. This study assesses differences in kidney transplant activity, waiting list durations, and renal replacement therapy usage during pre-pandemic and pandemic periods.
Methods: This observational study was conducted at Miguel Servet University Hospital in Zaragoza, analyzing 326 kidney transplants performed between 2017 and 2022. Two periods were defined: pre-pandemic (2017-2020) and pandemic (2020-2022). Data were sourced from hospital records, excluding living or combined donor transplants. Statistical analyses included Kaplan-Meier survival curves and Cox regression models.
Results: Median waiting list times increased from 3 months in the pre-pandemic period to 7.5 months during the pandemic (p=0.0014). Transplant density decreased from 5.02 to 4.21 cases per month. The proportion of donors in asystole rose significantly from 15.1% to 34.8%. Men over 61.9 years were the most impacted demographic.
Conclusions: The pandemic significantly extends waiting times and reduces kidney transplant activities, disproportionately affecting older male patients. These findings underscore the necessity of optimizing healthcare resources in future crises.
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