首页 > 最新文献

WMJ : official publication of the State Medical Society of Wisconsin最新文献

英文 中文
Knowledge, Attitudes, and Behaviors Regarding Pneumococcal Vaccines in Adults 65 Years and Older in Primary Care in Wisconsin. 威斯康星州 65 岁及以上接受初级保健的成年人对肺炎球菌疫苗的了解、态度和行为。
Mary F Henningfield, Alice Yuroff, Lisa Sampson, Paul H Hunter

Introduction: Although shared decision-making is highly valued, its implementation in clinical practice is suboptimal. Shared decision-making was included in the Centers for Disease Control and Prevention (CDC) recommendations for the pneumococcal conjugate vaccine 13 valent for older adults. As a first step to develop and test clinician educational resources to facilitate shared decision-making for pneumococcal vaccines for older adults, we completed a needs assessment to identify knowledge gaps, attitudes, and behaviors.

Methods: Primary care clinicians, pharmacists, and patient care staff completed a questionnaire on shared decision-making and pneumococcal vaccines. After the CDC recommended new pneumococcal vaccines and eliminated the role of shared decision-making, a revised questionnaire was distributed to additional clinicians in an effort to increase the sample size.

Results: Knowledge of pneumococcal vaccine recommendations was high among those who responded to knowledge questions (48 of 75 respondents). Although 96% of respondents believed shared decision-making for use of pneumococcal vaccines in adults 65 years or older was feasible, 25% responded that it would be "somewhat difficult" to explain potential harms and benefits of PCV13.

Discussion: Although shared decision-making was reported to be feasible, challenges implementing it are ongoing. Knowledge gaps regarding pneumococcal vaccines were observed, highlighting the need for ongoing medical education with changing vaccine recommendations.

介绍:尽管共同决策受到高度重视,但其在临床实践中的执行情况却不尽如人意。美国疾病控制和预防中心 (CDC) 建议老年人接种 13 价肺炎球菌结合疫苗时纳入共同决策。作为开发和测试临床医生教育资源以促进老年人肺炎球菌疫苗共同决策的第一步,我们完成了一项需求评估,以确定知识差距、态度和行为:方法: 初级医疗临床医生、药剂师和患者护理人员填写了一份关于共同决策和肺炎球菌疫苗的问卷。在美国疾病预防控制中心推荐了新的肺炎球菌疫苗并取消了共同决策的作用后,我们向更多的临床医生分发了修订后的问卷,以增加样本量:回答知识问题的受访者对肺炎球菌疫苗建议的了解程度较高(75 位受访者中有 48 位)。虽然 96% 的受访者认为在 65 岁或以上的成年人中使用肺炎球菌疫苗的共同决策是可行的,但 25% 的受访者回答说解释 PCV13 的潜在危害和益处 "有些困难":讨论:尽管报告称共同决策是可行的,但在实施过程中仍面临挑战。我们观察到了有关肺炎球菌疫苗的知识缺口,这凸显了根据不断变化的疫苗建议持续开展医学教育的必要性。
{"title":"Knowledge, Attitudes, and Behaviors Regarding Pneumococcal Vaccines in Adults 65 Years and Older in Primary Care in Wisconsin.","authors":"Mary F Henningfield, Alice Yuroff, Lisa Sampson, Paul H Hunter","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Although shared decision-making is highly valued, its implementation in clinical practice is suboptimal. Shared decision-making was included in the Centers for Disease Control and Prevention (CDC) recommendations for the pneumococcal conjugate vaccine 13 valent for older adults. As a first step to develop and test clinician educational resources to facilitate shared decision-making for pneumococcal vaccines for older adults, we completed a needs assessment to identify knowledge gaps, attitudes, and behaviors.</p><p><strong>Methods: </strong>Primary care clinicians, pharmacists, and patient care staff completed a questionnaire on shared decision-making and pneumococcal vaccines. After the CDC recommended new pneumococcal vaccines and eliminated the role of shared decision-making, a revised questionnaire was distributed to additional clinicians in an effort to increase the sample size.</p><p><strong>Results: </strong>Knowledge of pneumococcal vaccine recommendations was high among those who responded to knowledge questions (48 of 75 respondents). Although 96% of respondents believed shared decision-making for use of pneumococcal vaccines in adults 65 years or older was feasible, 25% responded that it would be \"somewhat difficult\" to explain potential harms and benefits of PCV13.</p><p><strong>Discussion: </strong>Although shared decision-making was reported to be feasible, challenges implementing it are ongoing. Knowledge gaps regarding pneumococcal vaccines were observed, highlighting the need for ongoing medical education with changing vaccine recommendations.</p>","PeriodicalId":94268,"journal":{"name":"WMJ : official publication of the State Medical Society of Wisconsin","volume":"123 3","pages":"204-209"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141725452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Unusual Case of Disseminated Erdheim-Chester Disease. 一个罕见的播散性埃尔德海姆-切斯特病病例
Samira Samant, Andrii Puzyrenko, Haisam Abid

Introduction: Erdheim-Chester disease (ECD) is a rare non-Langerhans histiocytic multisystem disorder, deriving from mononuclear phagocytic cells. It is notoriously challenging to diagnose. Here we present a case of a patient with multisystem ECD.

Case presentation: A 76-year-old female with a history of Hashimoto's thyroiditis who presented with persistent leukocytosis was found to have bilateral renal enlargement with a perinephric mass, a recurrent pericardial effusion, and bilateral pleural effusions. Following biopsies of several sites of involvement, a diagnosis of ECD was made.

Discussion: The existing literature on ECD is sparse, and no diagnostic criteria have been put forward due to widely differing presentations, although the most common is skeletal. Definitive diagnosis requires a tissue sample.

Conclusions: In presenting our clinical reasoning and approach, we hope to contribute to the existing body of literature on ECD, with the aim of ultimately having sufficient data to compile a diagnostic framework for other clinicians who encounter ECD.

简介埃尔德海姆-切斯特病(Erdheim-Chester disease,ECD)是一种罕见的非朗格汉斯组织细胞性多系统疾病,源于单核吞噬细胞。该病的诊断极具挑战性。在此,我们介绍一例多系统 ECD 患者:一位 76 岁的女性患者,曾患桥本氏甲状腺炎,出现持续性白细胞增多,后发现双侧肾脏肿大伴肾周肿块、反复心包积液和双侧胸腔积液。在对多个受累部位进行活检后,确诊为 ECD:讨论:有关 ECD 的现有文献很少,而且由于表现形式千差万别,尽管最常见的是骨骼型,但尚未提出诊断标准。明确诊断需要组织样本:通过介绍我们的临床推理和方法,我们希望能对现有的 ECD 文献有所贡献,以期最终获得足够的数据,为其他遇到 ECD 的临床医生编制一个诊断框架。
{"title":"An Unusual Case of Disseminated Erdheim-Chester Disease.","authors":"Samira Samant, Andrii Puzyrenko, Haisam Abid","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Erdheim-Chester disease (ECD) is a rare non-Langerhans histiocytic multisystem disorder, deriving from mononuclear phagocytic cells. It is notoriously challenging to diagnose. Here we present a case of a patient with multisystem ECD.</p><p><strong>Case presentation: </strong>A 76-year-old female with a history of Hashimoto's thyroiditis who presented with persistent leukocytosis was found to have bilateral renal enlargement with a perinephric mass, a recurrent pericardial effusion, and bilateral pleural effusions. Following biopsies of several sites of involvement, a diagnosis of ECD was made.</p><p><strong>Discussion: </strong>The existing literature on ECD is sparse, and no diagnostic criteria have been put forward due to widely differing presentations, although the most common is skeletal. Definitive diagnosis requires a tissue sample.</p><p><strong>Conclusions: </strong>In presenting our clinical reasoning and approach, we hope to contribute to the existing body of literature on ECD, with the aim of ultimately having sufficient data to compile a diagnostic framework for other clinicians who encounter ECD.</p>","PeriodicalId":94268,"journal":{"name":"WMJ : official publication of the State Medical Society of Wisconsin","volume":"123 3","pages":"229-232"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141725443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Future of Global Neurosurgery: Invest in People and Education in Areas of Need. 全球神经外科的未来:在需要的领域投资人才和教育。
Robert J Dempsey, Robert N Golden
{"title":"The Future of Global Neurosurgery: Invest in People and Education in Areas of Need.","authors":"Robert J Dempsey, Robert N Golden","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":94268,"journal":{"name":"WMJ : official publication of the State Medical Society of Wisconsin","volume":"123 3","pages":"241-242"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141725461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Partnering is Paramount: Engaging Care Partners to Improve Delirium Identification. 合作至关重要:让护理合作伙伴参与进来,提高谵妄识别能力。
Blair P Golden, Farah A Kaiksow, Amy Jh Kind
{"title":"Partnering is Paramount: Engaging Care Partners to Improve Delirium Identification.","authors":"Blair P Golden, Farah A Kaiksow, Amy Jh Kind","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":94268,"journal":{"name":"WMJ : official publication of the State Medical Society of Wisconsin","volume":"123 3","pages":"163-165"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141725455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Qualitative Pilot Study: Longitudinal Perspectives From People Who Had Second Trimester Abortions for Fetal Anomaly. 定性试点研究:因胎儿畸形进行第二孕期人工流产者的纵向视角。
Elise S Cowley, Taryn M Valley, Kelsey Christianson, Suzanne Walczak, Jessica A Greenblatt, Laura Jacques

Background: We investigated patient experience with abortion for fetal anomaly, about which little is known.

Methods: This qualitative, longitudinal pilot study surveyed 7 patients twice after abortion for fetal anomaly, initially 4 to 5 days after the abortion and a follow-up 3 months post-abortion, at a single Wisconsin hospital from July 2012 to February 2014.

Results: Patients indicated that having a choice to have an abortion and choose the modality is imperative, and they remained certain in their decision-making over time. They also described initially strong, then lacking, social support; processed grief; and identified resource constraints.

Discussion: Patients emphasized the importance of having the choice to choose abortion and the abortion modality, remaining confident in their decision-making over time. This qualitative pilot study provides areas for future intervention to improve care for people undergoing abortion for fetal anomaly.

背景:我们调查了因胎儿畸形而进行人工流产的患者经历:我们调查了因胎儿畸形而进行人工流产的患者的经历,而人们对此知之甚少:2012年7月至2014年2月,我们在威斯康星州的一家医院对7名因胎儿畸形而进行人工流产的患者进行了两次纵向定性试点研究调查,最初是在人工流产后4至5天,随后是在人工流产后3个月:结果:患者表示,选择进行人工流产和选择人工流产方式是必要的,而且随着时间的推移,他们对自己的决策仍然很确定。他们还描述了起初强大、后来缺乏的社会支持;悲伤的过程;以及发现的资源限制:讨论:患者强调选择人工流产和人工流产方式的重要性,并随着时间的推移对其决策保持信心。这项定性试点研究提供了未来干预的领域,以改善对因胎儿异常而接受人工流产者的护理。
{"title":"Qualitative Pilot Study: Longitudinal Perspectives From People Who Had Second Trimester Abortions for Fetal Anomaly.","authors":"Elise S Cowley, Taryn M Valley, Kelsey Christianson, Suzanne Walczak, Jessica A Greenblatt, Laura Jacques","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>We investigated patient experience with abortion for fetal anomaly, about which little is known.</p><p><strong>Methods: </strong>This qualitative, longitudinal pilot study surveyed 7 patients twice after abortion for fetal anomaly, initially 4 to 5 days after the abortion and a follow-up 3 months post-abortion, at a single Wisconsin hospital from July 2012 to February 2014.</p><p><strong>Results: </strong>Patients indicated that having a choice to have an abortion and choose the modality is imperative, and they remained certain in their decision-making over time. They also described initially strong, then lacking, social support; processed grief; and identified resource constraints.</p><p><strong>Discussion: </strong>Patients emphasized the importance of having the choice to choose abortion and the abortion modality, remaining confident in their decision-making over time. This qualitative pilot study provides areas for future intervention to improve care for people undergoing abortion for fetal anomaly.</p>","PeriodicalId":94268,"journal":{"name":"WMJ : official publication of the State Medical Society of Wisconsin","volume":"123 3","pages":"177-181"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141725458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
'I'm So Proud of How Hard You're Trying': A Photovoice Analysis of Youth Mental Health and Wellness in Wisconsin. 我为你的努力感到骄傲":威斯康星州青少年心理健康与幸福的摄影选择分析》。
Sara Kohlbeck, Patricia Monroe

Understanding youth and young adult mental health and well-being is critical to addressing rates of suicide among this population. This qualitative study sought to gather additional perspectives of students across Wisconsin using photovoice methods to enhance understanding of their experiences and to inform future policies and programs. A total of 11 youth and young adults ages 14 to 26 participated by taking pictures in response to given prompts and then discussing those pictures within a virtual focus group. Spanning the social-ecological framework, 4 themes emerged from the photographs and discussion: (1) individual-level factors drive mental health and well-being; (2) the support of interpersonal relationships is crucial; (3) school-related factors are predominant sources of stress; (4) policies, culture, and systems influence well-being. This study highlights the unique experiences of youth and young adults and underscores the impact of systems and structures on their mental health and well-being.

了解青少年和年轻成年人的心理健康和福祉对于解决这一人群的自杀率问题至关重要。这项定性研究试图通过摄影选言方法收集威斯康星州学生的更多观点,以加深对他们经历的了解,并为未来的政策和计划提供参考。共有 11 名 14 至 26 岁的青少年参与了这项研究,他们根据给定的提示拍摄照片,然后在虚拟焦点小组中讨论这些照片。在社会生态框架下,从照片和讨论中得出了 4 个主题:(1)个人层面的因素驱动着心理健康和幸福感;(2)人际关系的支持至关重要;(3)与学校相关的因素是压力的主要来源;(4)政策、文化和制度影响着幸福感。本研究强调了青少年的独特经历,并强调了制度和结构对其心理健康和幸福感的影响。
{"title":"'I'm So Proud of How Hard You're Trying': A Photovoice Analysis of Youth Mental Health and Wellness in Wisconsin.","authors":"Sara Kohlbeck, Patricia Monroe","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Understanding youth and young adult mental health and well-being is critical to addressing rates of suicide among this population. This qualitative study sought to gather additional perspectives of students across Wisconsin using photovoice methods to enhance understanding of their experiences and to inform future policies and programs. A total of 11 youth and young adults ages 14 to 26 participated by taking pictures in response to given prompts and then discussing those pictures within a virtual focus group. Spanning the social-ecological framework, 4 themes emerged from the photographs and discussion: (1) individual-level factors drive mental health and well-being; (2) the support of interpersonal relationships is crucial; (3) school-related factors are predominant sources of stress; (4) policies, culture, and systems influence well-being. This study highlights the unique experiences of youth and young adults and underscores the impact of systems and structures on their mental health and well-being.</p>","PeriodicalId":94268,"journal":{"name":"WMJ : official publication of the State Medical Society of Wisconsin","volume":"123 3","pages":"189-194"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141725449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perspectives on Electronic Nicotine Delivery System Use Cessation Among Adults in Rural Areas: Implications for Future Studies. 农村地区成人戒烟使用电子尼古丁输送系统的前景:对未来研究的启示
Seok Hyun Gwon, Vipavee Thongpriwan, Yourim Kim, Imteyaz El Jarrah, Amani Mobarki, Young Ik Cho, Han Joo Lee, Alex Nelson, Devon Noonan

Introduction: More young adults (age 18-24 years) in rural areas versus urban areas use electronic nicotine delivery systems (ENDS) - also known as e-cigarettes. Little is known about young adults' perceptions toward ENDS use and cessation. The objective of this study was to examine barriers and facilitators to ENDS use cessation among young adults living in rural areas, as well as their perceptions about ENDS use and cessation and to determine implications for future cessation studies.

Methods: We administered cross-sectional online surveys to young adults living in rural Midwestern counties. A total of 100 individuals responded to the surveys. Descriptive statistics were used to report their perceptions of ENDS use as well as barriers and facilitators to ENDS use cessation. The content analysis method was used to analyze the answers to an open-ended question regarding perceptions about the ENDS use cessation in the context of rural areas.

Results: Barriers to ENDS use cessation included perceived advantages to ENDS use, high nicotine dependence, and the perception that ENDS use was less harmful cigarettes. Facilitators to ENDS use cessation included cost of ENDS use, perceived harm, and high confidence in ability to quit. Participants' perceptions about ENDS use cessation in the context of rural areas were conceptualized under the themes of (1) exposure to and initiation of ENDS use, (2) continuation of ENDS use, and (3) prevention and cessation of ENDS use.

Conclusions: Health care providers, tobacco control researchers, and public health advocates should be aware of barriers and facilitators to ENDS use cessation among young adults for future cessation intervention studies relevant specifically to rural areas.

导言:与城市地区相比,农村地区使用电子尼古丁输送系统(ENDS)(也称电子烟)的年轻人(18-24 岁)更多。人们对青壮年使用和戒烟的看法知之甚少。本研究旨在调查生活在农村地区的年轻人戒烟的障碍和促进因素,以及他们对ENDS使用和戒烟的看法,并确定对未来戒烟研究的影响:我们对生活在中西部农村地区的年轻人进行了横断面在线调查。共有 100 人回复了调查。我们使用描述性统计来报告他们对ENDS使用的看法以及戒烟的障碍和促进因素。内容分析法用于分析对一个开放式问题的回答,该问题涉及农村地区对ENDS戒烟的看法:结果显示:ENDS戒烟的障碍包括认为使用ENDS有好处、尼古丁依赖性高以及认为使用ENDS对香烟危害较小。ENDS戒烟的促进因素包括使用ENDS的成本、对危害的认知以及对戒烟能力的高度自信。在农村地区,参与者对ENDS戒烟的看法被归纳为以下几个主题:(1)接触和开始使用ENDS;(2)继续使用ENDS;(3)预防和停止使用ENDS:结论:医疗服务提供者、烟草控制研究人员和公共卫生倡导者应了解青壮年戒烟的障碍和促进因素,以便今后开展专门针对农村地区的戒烟干预研究。
{"title":"Perspectives on Electronic Nicotine Delivery System Use Cessation Among Adults in Rural Areas: Implications for Future Studies.","authors":"Seok Hyun Gwon, Vipavee Thongpriwan, Yourim Kim, Imteyaz El Jarrah, Amani Mobarki, Young Ik Cho, Han Joo Lee, Alex Nelson, Devon Noonan","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>More young adults (age 18-24 years) in rural areas versus urban areas use electronic nicotine delivery systems (ENDS) - also known as e-cigarettes. Little is known about young adults' perceptions toward ENDS use and cessation. The objective of this study was to examine barriers and facilitators to ENDS use cessation among young adults living in rural areas, as well as their perceptions about ENDS use and cessation and to determine implications for future cessation studies.</p><p><strong>Methods: </strong>We administered cross-sectional online surveys to young adults living in rural Midwestern counties. A total of 100 individuals responded to the surveys. Descriptive statistics were used to report their perceptions of ENDS use as well as barriers and facilitators to ENDS use cessation. The content analysis method was used to analyze the answers to an open-ended question regarding perceptions about the ENDS use cessation in the context of rural areas.</p><p><strong>Results: </strong>Barriers to ENDS use cessation included perceived advantages to ENDS use, high nicotine dependence, and the perception that ENDS use was less harmful cigarettes. Facilitators to ENDS use cessation included cost of ENDS use, perceived harm, and high confidence in ability to quit. Participants' perceptions about ENDS use cessation in the context of rural areas were conceptualized under the themes of (1) exposure to and initiation of ENDS use, (2) continuation of ENDS use, and (3) prevention and cessation of ENDS use.</p><p><strong>Conclusions: </strong>Health care providers, tobacco control researchers, and public health advocates should be aware of barriers and facilitators to ENDS use cessation among young adults for future cessation intervention studies relevant specifically to rural areas.</p>","PeriodicalId":94268,"journal":{"name":"WMJ : official publication of the State Medical Society of Wisconsin","volume":"123 2","pages":"99-105"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140890637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute Myelomonocytic Leukemia Presenting as Fournier's Gangrene. 急性髓单核细胞白血病表现为福尼尔坏疽
Sofie Kjellesvig, Emelyn Zaworski, Antoine N Saliba

Introduction: Acute myelomonocytic leukemia is a type of acute myeloid leukemia with monocytic expansion. Both the disease and its treatment can be immunocompromising. Immunocompromised patients are more susceptible to infections, such as Fournier's gangrene, a rare necrotizing infection of the groin.

Case presentation: A 56-year-old male presented to the emergency department with abdominal pain, leukocytosis, and perineal ecchymosis. Overnight, his perineal discoloration and tenderness worsened. He underwent irrigation and debridement for Fournier's gangrene and received broad-spectrum antimicrobial therapy. Subsequent workup revealed acute myeloid leukemia with leukemia cutis and central nervous system involvement, necessitating chemotherapy initiation prior to complete wound healing.

Discussion/conclusions: This case highlights the challenges in the diagnosis and management of acute leukemia in the setting of a concomitant life-threatening soft tissue infection, as both the hematologic disease and treatment thereof can exacerbate infectious complications.

导言急性髓单核细胞白血病是一种单核细胞扩增的急性髓系白血病。急性髓单核细胞白血病及其治疗均可导致免疫力下降。免疫力低下的患者更容易受到感染,如福尼尔坏疽,这是一种罕见的腹股沟坏死性感染:一名 56 岁的男性因腹痛、白细胞增多和会阴部瘀斑到急诊科就诊。一夜之间,他的会阴部变色和疼痛加剧。他接受了冲洗和清创术治疗 Fournier 坏疽,并接受了广谱抗菌治疗。随后的检查发现他患有急性髓性白血病,并伴有切口白血病和中枢神经系统受累,因此必须在伤口完全愈合前开始化疗:本病例凸显了在并发危及生命的软组织感染的情况下诊断和治疗急性白血病所面临的挑战,因为血液病及其治疗都会加重感染并发症。
{"title":"Acute Myelomonocytic Leukemia Presenting as Fournier's Gangrene.","authors":"Sofie Kjellesvig, Emelyn Zaworski, Antoine N Saliba","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Acute myelomonocytic leukemia is a type of acute myeloid leukemia with monocytic expansion. Both the disease and its treatment can be immunocompromising. Immunocompromised patients are more susceptible to infections, such as Fournier's gangrene, a rare necrotizing infection of the groin.</p><p><strong>Case presentation: </strong>A 56-year-old male presented to the emergency department with abdominal pain, leukocytosis, and perineal ecchymosis. Overnight, his perineal discoloration and tenderness worsened. He underwent irrigation and debridement for Fournier's gangrene and received broad-spectrum antimicrobial therapy. Subsequent workup revealed acute myeloid leukemia with leukemia cutis and central nervous system involvement, necessitating chemotherapy initiation prior to complete wound healing.</p><p><strong>Discussion/conclusions: </strong>This case highlights the challenges in the diagnosis and management of acute leukemia in the setting of a concomitant life-threatening soft tissue infection, as both the hematologic disease and treatment thereof can exacerbate infectious complications.</p>","PeriodicalId":94268,"journal":{"name":"WMJ : official publication of the State Medical Society of Wisconsin","volume":"123 2","pages":"131-134"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140893121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hypokalemia Due to Ectopic Adrenocorticotropic Hormone. 异位促肾上腺皮质激素导致的低钾血症。
Adil Ghaffar, Tripti Singh

Hypokalemia is a common disorder in clinical practice. The underlying pathophysiology can be attributed to 3 main mechanisms: insufficient potassium intake, excessive urinary or gastrointestinal losses, and transcellular shift. Renal loss is the most common cause of hypokalemia. Renal loss of potassium can occur due to diuretics, mineralocorticoid excess or hypercortisolism (Cushing syndrome). Among patients with Cushing syndrome, ectopic adrenocorticotropic hormone (ACTH) is the most frequent cause. We present a case of hypokalemia and hypertension due to ectopic ACTH production leading to Cushing syndrome.

低钾血症是临床上常见的一种疾病。其潜在的病理生理学可归因于三种主要机制:钾摄入不足、泌尿或胃肠道损失过多以及跨细胞转移。肾丢失是低钾血症最常见的原因。利尿剂、矿物质皮质激素过量或皮质醇分泌过多(库欣综合征)都可能导致肾失钾。在库欣综合征患者中,异位促肾上腺皮质激素(ACTH)是最常见的原因。我们介绍了一例因异位促肾上腺皮质激素分泌导致库欣综合征而引起低钾血症和高血压的病例。
{"title":"Hypokalemia Due to Ectopic Adrenocorticotropic Hormone.","authors":"Adil Ghaffar, Tripti Singh","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Hypokalemia is a common disorder in clinical practice. The underlying pathophysiology can be attributed to 3 main mechanisms: insufficient potassium intake, excessive urinary or gastrointestinal losses, and transcellular shift. Renal loss is the most common cause of hypokalemia. Renal loss of potassium can occur due to diuretics, mineralocorticoid excess or hypercortisolism (Cushing syndrome). Among patients with Cushing syndrome, ectopic adrenocorticotropic hormone (ACTH) is the most frequent cause. We present a case of hypokalemia and hypertension due to ectopic ACTH production leading to Cushing syndrome.</p>","PeriodicalId":94268,"journal":{"name":"WMJ : official publication of the State Medical Society of Wisconsin","volume":"123 2","pages":"135-137"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140893158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Follmann Balanitis: An Unusual Case of Syphilis. Follmann Balanitis:梅毒的罕见病例
Milan Patel, Paige Gioia, Pinky Jha

A 33-year-old man presented with suprapubic abdominal pain and small vesicular lesions on the foreskin of the penis. Based on the presentation, he was empirically treated for genital herpes, although the herpes simplex virus swab was negative. He returned to the emergency department 4 months after his initial presentation with worsening symptoms that were consistent with balanoposthitis and cystitis. He was tachycardic and febrile on presentation. He denied any sexual contact for the last 3 months, with previous negative screening tests for sexually transmitted infections. Syphilis was eventually diagnosed during this admission. The incidence rates of syphilis have increased in recent years, and the infection is often undiagnosed given atypical manifestations. Here we present an atypical manifestation of syphilis that was initially misdiagnosed as herpes simplex virus.

一名 33 岁的男子因耻骨上腹痛和阴茎包皮上的小水泡病变就诊。根据病史,他接受了生殖器疱疹的经验性治疗,但单纯疱疹病毒拭子检测结果呈阴性。初次就诊 4 个月后,他因包茎和膀胱炎症状加重再次来到急诊科就诊。就诊时他心动过速并发热。他否认在过去 3 个月中有过任何性接触,之前的性传播感染筛查呈阴性。入院时最终确诊为梅毒。近年来,梅毒的发病率有所上升,但由于表现不典型,梅毒感染往往得不到诊断。在此,我们介绍一种最初被误诊为单纯疱疹病毒的梅毒非典型表现。
{"title":"Follmann Balanitis: An Unusual Case of Syphilis.","authors":"Milan Patel, Paige Gioia, Pinky Jha","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A 33-year-old man presented with suprapubic abdominal pain and small vesicular lesions on the foreskin of the penis. Based on the presentation, he was empirically treated for genital herpes, although the herpes simplex virus swab was negative. He returned to the emergency department 4 months after his initial presentation with worsening symptoms that were consistent with balanoposthitis and cystitis. He was tachycardic and febrile on presentation. He denied any sexual contact for the last 3 months, with previous negative screening tests for sexually transmitted infections. Syphilis was eventually diagnosed during this admission. The incidence rates of syphilis have increased in recent years, and the infection is often undiagnosed given atypical manifestations. Here we present an atypical manifestation of syphilis that was initially misdiagnosed as herpes simplex virus.</p>","PeriodicalId":94268,"journal":{"name":"WMJ : official publication of the State Medical Society of Wisconsin","volume":"123 2","pages":"144-146"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140893157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
WMJ : official publication of the State Medical Society of Wisconsin
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1