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The use of robotic surgery for the management of urethral strictures and bladder neck contractures: A systematic review 机器人手术在尿道狭窄和膀胱颈挛缩治疗中的应用:系统综述。
Pub Date : 2025-01-01 DOI: 10.1016/j.acuroe.2024.11.006
G. Mantica , F. Chierigo , Ł. Białek , F.X. Madec , M. Frankiewicz , W. Verla , E.J. Redmond , C.M. Rosenbaum , A. Cocci , F. Campos-Juanatey , M. Oszczudłowski , J. Adamowicz , C. Terrone , M.W. Vetterlein , en representación del Grupo de Trabajo de Urología Reconstructiva y Trauma Urológico de la Sección de Jóvenes Urólogos Académicos - Asociación Europea de Urología

Objective

The aim of this systematic review is to offer a comprehensive view of the current use of robotic surgery for the treatment of urethral strictures and bladder neck contractures.

Methods

A systematic review of the current literature was conducted through the Medline and NCBI PubMed, Embase databases in December 2023. Keywords used were “robotic” and “robotic-assisted” combined with “urethroplasty”, “urethral stricture”, and “bladder neck contracture”. All papers published after 2000, concerning studies conducted on humans for urethral strictures and bladder neck contractures managed with robotic surgery were considered for the review. Only procedures involving a direct approach to urethra/bladder neck and/or graft harvesting for urethroplasty have been included.

Results

A total of 275 articles were evaluated after the strategy search and only 11 articles were considered eligible for the final analysis. The studies included a series of between a minimum of 1 and a maximum of 104 patients, for a total of 203 patients. The robotic surgery was performed mainly for the treatment of bladder neck contracture and posterior urethra. In some reports, the robotic system was used for graft harvesting, subsequently used with an open perineal technique. The follow-up presented in the different studies is very heterogeneous. However, most studies have high success rates, with recurrence and redo surgery rates generally below 20%. Likewise, post-procedure incontinence rates are low.

Conclusions

The outcomes presented in the literature, combined with the minimally invasive nature, suggest a possible growing role for robotic surgery in the coming years in the treatment of these diseases.
目的:本系统综述的目的是提供一个全面的观点,目前使用机器人手术治疗尿道狭窄和膀胱颈挛缩。方法:于2023年12月通过Medline和NCBI PubMed, Embase数据库对当前文献进行系统综述。关键词:“机器人”、“机器人辅助”联合“尿道成形术”、“尿道狭窄”、“膀胱颈挛缩”。所有2000年以后发表的关于机器人手术治疗人类尿道狭窄和膀胱颈挛缩的研究的论文都被纳入综述。仅包括直接入路尿道/膀胱颈和/或尿道成形术的移植手术。结果:策略检索后共评估了275篇文章,只有11篇文章被认为符合最终分析的条件。这些研究包括一系列最少1例到最多104例患者,总共203例患者。机器人手术主要用于治疗膀胱颈挛缩和后尿道。在一些报道中,机器人系统被用于移植收获,随后与开放会阴技术一起使用。在不同的研究中提出的随访是非常不同的。然而,大多数研究都有很高的成功率,复发率和重做手术率通常低于20%。同样,术后尿失禁率也很低。结论:文献中提出的结果,结合微创性,表明机器人手术在未来几年治疗这些疾病中的作用可能越来越大。
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引用次数: 0
Efficacy and safety of Optilume® paclitaxel-coated urethral dilatation balloon in real-life: experience in a Spanish multicenter study Optilume® 紫杉醇涂层尿道扩张球囊在现实生活中的有效性和安全性:西班牙多中心研究的经验。
Pub Date : 2025-01-01 DOI: 10.1016/j.acuroe.2024.10.003
C. Ballesteros Ruiz , F. Campos-Juanatey , I. Povo Martín , S. Mitjana Biosca , Ó. Gorría Cardesa , J.F. Aguilar Guevara , N. García Formoso , E. Fernández Pascual , J.I. Martínez Salamanca , S. Martínez Pérez , J.M. Alonso Dorrego , E. Ríos González , S. San Cayetano Talegón , A.M. Araujo Suarez , E. Moran Pascual , M.Á. Bonillo García , J. Medina Polo , L. Viver Clotet , A.J. Vicens Morton , J. Arce Gil , L. Martínez-Piñeiro Lorenzo

Introduction

The Optilume® Paclitaxel-coated urethral dilatation balloon is an alternative to conventional endoscopic treatments that combines mechanical dilatation with local delivery of paclitaxel.

Objective

To describe the success rate and analyze the safety of the device in real clinical practice. To evaluate possible predictors of treatment failure.

Materials and methods

Retrospective multicenter study in patients diagnosed with urethral stricture and treated with an Optilume® balloon in routine clinical practice. Data were collected from flowmetry, questionnaires (PROM and IPSS) and cystoscopy before surgery, and 3, 6 and 12 months after the procedure, according to standard practice. Surgical success was defined as the absence of subsequent urethral manipulation and a Qmax >10 ml/s.

Results

238 patients treated with Optilume® in 12 Spanish hospitals between May 2021 and April 2024 were included in the study. Of these, 156 who had a minimum follow-up of 3 months, were analyzed. Median stricture length: 1.5 cm (0.5–5.3), mainly in bulbar urethra (87.7%). Of the total, 12.8% of patients had a history of pelvic radiotherapy, and 81.4% had undergone prior urethral manipulation. Postoperative complications were reported in 14.2% of the total. The treatment success rate was 73.8%, with a median follow-up of 8 months (5–12). No predictors of stricture recurrence were identified. Recurrence rates were higher in strictures located in the posterior versus anterior urethra (42.9% vs. 24.6%, p = 0.126). No significant differences were observed between patients with and without prior urethral manipulation.

Conclusion

Treatment with Optilume® has been shown to be safe and effective in short-term routine clinical practice.
简介:Optilume® 紫杉醇涂层尿道扩张球囊是传统内窥镜治疗的替代方法,它将机械扩张与紫杉醇局部给药相结合:描述该设备在实际临床实践中的成功率并分析其安全性。评估治疗失败的可能预测因素:回顾性多中心研究,对象是在常规临床实践中被诊断为尿道狭窄并接受 Optilume® 球囊治疗的患者。按照标准做法,在术前、术后 3 个月、6 个月和 12 个月通过流量计、问卷调查(PROM 和 IPSS)和膀胱镜检查收集数据。手术成功的定义是没有后续的尿道操作,Qmax > 10 ml/s。结果:2021 年 5 月至 2024 年 4 月期间,在西班牙 12 家医院接受 Optilume® 治疗的 238 名患者被纳入研究。对其中至少随访 3 个月的 156 名患者进行了分析。中位狭窄长度:1.5 厘米(0.5 - 5.3),主要位于球部尿道(87.7%)。其中,12.8%的患者曾接受过盆腔放疗,81.4%的患者曾接受过尿道操作。据报告,14.2%的患者出现了术后并发症。治疗成功率为 73.8%,中位随访时间为 8 个月(5-12 个月)。没有发现狭窄复发的预测因素。位于后尿道的狭窄复发率高于前尿道(42.9% 对 24.6%,P = 0.126)。结论:使用 Optilume® 治疗尿道狭窄的效果良好:结论:在短期常规临床实践中,使用 Optilume® 治疗已被证明是安全有效的。
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引用次数: 0
Urethral stricture management knowledge survey among Spanish urology residents 西班牙泌尿外科住院医师尿道狭窄管理知识调查。
Pub Date : 2025-01-01 DOI: 10.1016/j.acuroe.2024.11.003
E. Fes Ascanio , L.E. Ortega Polledo , M.E. Zegrí de Olivar , C.A. Muñoz Bastidas , E. Seguí Moya , D.M. Carrión Monsalve , M. Sánchez García , F. Campos-Juanatey

Introduction and objective

Assessment of urethral stricture (US) management in a specific group of professionals, Urology Residents, in a specific region (Spain), seems to be important to determine the quality of the educational program and design educational interventions to improve it. We aim to investigate diagnosis and therapeutics practices among Urology Residents for the US management.

Materials and methods

20-question on-line survey was conducted among residents and junior consultants registered on the mailing list of residents and young urologists of the Spanish Association of Urology (RAEU) group of the educational period 2018–2023. We evaluated demographic, educational, surgical technics and experience data during the training period. 290 questionnaires were mailed between May-August 2023. Data was collected in a prospective way between May-December 2023.

Results

The survey obtained 86 responders, with 29,7% (86/290) response rate. Two first sections were answered by all the responders, however, from the assessment section on, only 57 responders completed the survey, which represents 66,3% of them.

Conclusions

Educational program in Reconstructive Urology among Urology Residents in Spain has an improvement margin. We must dedicate our efforts to standardize the educational process and facilitate access to formation to and increasing area of interest among residents.
前言和目的:评估尿道狭窄(US)管理的一组专业人员,泌尿外科住院医师,在一个特定的地区(西班牙),似乎是重要的决定教育计划的质量和设计教育干预措施,以改善它。我们的目的是调查美国泌尿外科住院医师的诊断和治疗实践。材料与方法:对2018-2023年教育期西班牙泌尿外科学会(RAEU)分组住院医师和年轻泌尿科医师邮寄名单上注册的住院医师和初级咨询师进行在线调查,问卷共20题。我们评估了培训期间的人口统计、教育、手术技术和经验数据。在2023年5月至8月期间,共邮寄了290份问卷。在2023年5月至12月期间以前瞻性方式收集数据,回复率为29.6%。结果:共获得应答者86例,应答率为29.65%(86/290)。所有应答者都回答了前两个部分,然而,从评估部分开始,只有57个应答者完成了调查,占他们的66.28%。结论:西班牙泌尿外科住院医师的泌尿重建教育方案有一定的改进余地。我们必须努力使教育过程标准化,促进居民对形成和增加兴趣领域的接触。
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引用次数: 0
Assessment of predictive factors in endoscopic internal urethrotomy for bulbar urethral strictures 内窥镜内尿道切开术治疗球尿道狭窄的预测因素评估。
Pub Date : 2025-01-01 DOI: 10.1016/j.acuroe.2024.11.004
A. García Fernández , F. Campos-Juanatey , P. Calleja Hermosa , A. González Fernández , R. Varea Malo , J.L. Gutiérrez Baños

Introduction

Direct vision internal urethrotomy (DVIU) is usually the first treatment offered to patients with bulbar urethral strictures (US). Advances in devices and surgical techniques have contributed to reducing associated complications. Despite the favorable success rate of DVIU, various factors predicting better outcomes have been studied, including patient characteristics, stricture features, and procedural aspects. The main aim of our study is to assess predictive factors for success.

Methods

We conducted a retrospective descriptive study of patients who underwent endoscopic internal urethrotomy at our hospital over a 30 year period. Out of 788 DVIU performed, we selected 491 (62.3%) conducted for bulbar US with a minimum follow-up of 12 months. We examined clinical outcomes obtained, and assessed the relationship between different patient characteristics, stricture-related factors and procedural aspects related with clinical success—considered as the avoidance of further interventions for stricture recurrence. Descriptive statistics were calculated and parametrical and non-parametrical comparative tests were applied. Kaplan-Meier survival analysis was used for evaluating time until recurrence.

Results

Mean stricture length was 1.2 cm (SD 0.5), with only 12 patients presenting with more than 1 US in the bulbar area during DVIU. After a median follow-up of 170 months, 67.4% of patients did not experience clinical recurrence. Severe postoperative complications appear in 0.4% of cases, and need for overnight admission was 4.5%. A positive association was observed between clinical recurrence and a history of prior pelvic radiotherapy (OR 2.8, 95%IC 1.3–22.2), active smoking (OR 2.1, 95%IC 1.6–2.4), infectious etiology of stricture (OR 2.3, 95%IC 1.6–8), history of previous urethroplasty (OR 2.5, 95%IC 1.7–3.2), and higher postoperative urinary catheter sizes (OR 1.8 95%IC 1.1−2.9). Median time until recurrence after the first DVIU was 65 months, after the second was 60 months, after the third was 32 months, and after the fourth was 6 months.

Conclusions

Bulbar US could be safely managed with DVIU. The best clinical success is achieved in non-irradiated, non-smoker patients, without prior urethroplasties. The repetition of the procedure is significantly associated with a shorter time to clinical recurrence.
导读:直视内尿道切开术(DVIU)通常是球尿道狭窄(US)患者的首选治疗方法。器械和手术技术的进步有助于减少相关并发症。尽管DVIU具有良好的成功率,但预测更好结果的各种因素已被研究,包括患者特征、狭窄特征和手术方面。我们研究的主要目的是评估成功的预测因素。方法:我们对30年来在我院行内窥镜尿道切开术的患者进行回顾性描述性研究。在进行的788例DVIU中,我们选择了491例(62.3%)进行了球部US,随访时间至少为12个月。我们检查了获得的临床结果,并评估了不同患者特征、狭窄相关因素和与临床成功相关的手术方面之间的关系,这些因素被认为是避免进一步干预狭窄复发。计算描述性统计数据,并应用参数和非参数比较检验。Kaplan-Meier生存分析用于评估复发时间。结果:平均狭窄长度为1.2 cm (SD 0.5),仅有12例患者在DVIU期间出现球区超过1个US。中位随访170个月后,67.4%的患者没有出现临床复发。术后出现严重并发症的病例占0.4%,需要住院过夜的病例占4.5%。临床复发与既往盆腔放疗史(OR 2.8, 95%IC 1.3-22.2)、主动吸烟史(OR 2.1, 95%IC 1.6-2.4)、狭窄感染性病因史(OR 2.3, 95%IC 1.6-8)、既往尿道成形术史(OR 2.5, 95%IC 1.7-3.2)、术后尿管尺寸较大(OR 1.8 95%IC 1.1-2.9)呈正相关。第一次DVIU术后复发的中位时间为65个月,第二次为60个月,第三次为32个月,第四次为6个月。结论:DVIU可安全治疗球型US。最好的临床成功是在未接受过照射、不吸烟、没有既往尿道成形术的患者中取得的。重复手术与较短的临床复发时间显著相关。
{"title":"Assessment of predictive factors in endoscopic internal urethrotomy for bulbar urethral strictures","authors":"A. García Fernández ,&nbsp;F. Campos-Juanatey ,&nbsp;P. Calleja Hermosa ,&nbsp;A. González Fernández ,&nbsp;R. Varea Malo ,&nbsp;J.L. Gutiérrez Baños","doi":"10.1016/j.acuroe.2024.11.004","DOIUrl":"10.1016/j.acuroe.2024.11.004","url":null,"abstract":"<div><h3>Introduction</h3><div>Direct vision internal urethrotomy (DVIU) is usually the first treatment offered to patients with bulbar urethral strictures (US). Advances in devices and surgical techniques have contributed to reducing associated complications. Despite the favorable success rate of DVIU, various factors predicting better outcomes have been studied, including patient characteristics, stricture features, and procedural aspects. The main aim of our study is to assess predictive factors for success.</div></div><div><h3>Methods</h3><div>We conducted a retrospective descriptive study of patients who underwent endoscopic internal urethrotomy at our hospital over a 30 year period. Out of 788 DVIU performed, we selected 491 (62.3%) conducted for bulbar US with a minimum follow-up of 12 months. We examined clinical outcomes obtained, and assessed the relationship between different patient characteristics, stricture-related factors and procedural aspects related with clinical success—considered as the avoidance of further interventions for stricture recurrence. Descriptive statistics were calculated and parametrical and non-parametrical comparative tests were applied. Kaplan-Meier survival analysis was used for evaluating time until recurrence.</div></div><div><h3>Results</h3><div>Mean stricture length was 1.2 cm (SD 0.5), with only 12 patients presenting with more than 1 US in the bulbar area during DVIU. After a median follow-up of 170 months, 67.4% of patients did not experience clinical recurrence. Severe postoperative complications appear in 0.4% of cases, and need for overnight admission was 4.5%. A positive association was observed between clinical recurrence and a history of prior pelvic radiotherapy (OR 2.8, 95%IC 1.3–22.2), active smoking (OR 2.1, 95%IC 1.6–2.4), infectious etiology of stricture (OR 2.3, 95%IC 1.6–8), history of previous urethroplasty (OR 2.5, 95%IC 1.7–3.2), and higher postoperative urinary catheter sizes (OR 1.8 95%IC 1.1−2.9). Median time until recurrence after the first DVIU was 65 months, after the second was 60 months, after the third was 32 months, and after the fourth was 6 months.</div></div><div><h3>Conclusions</h3><div>Bulbar US could be safely managed with DVIU. The best clinical success is achieved in non-irradiated, non-smoker patients, without prior urethroplasties. The repetition of the procedure is significantly associated with a shorter time to clinical recurrence.</div></div>","PeriodicalId":94291,"journal":{"name":"Actas urologicas espanolas","volume":"49 1","pages":"Pages 94-101"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142776199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long term outcomes from uncorrected hypospadias: a scoping review 尿道下裂未矫正的长期后果:范围界定综述。
Pub Date : 2025-01-01 DOI: 10.1016/j.acuroe.2024.10.004
E. Bohane , M. Murphy , F. Chierigo , G. Mantica , J. Adamowicz , F. Campos-Juanatey , A. Cocci , M. Frankiewicz , C.M. Rosenbaum , W. Verla , M. Waterloos , Ł. Białek , F.X. Madec , M. Oszczudłowski , M.W. Vetterlein , E.J. Redmond , on behalf of the Trauma and Reconstructive Urology Working Party of the European Association of Urology Young Academic Urologists

Introduction

The goal of hypospadias repair is to optimize urinary and sexual function, improve cosmesis and minimise the psychosocial effects associated with a penile anomaly. However, a lack of clarity exists regarding the role of surgery in milder hypospadias where the anomaly is inconspicuous and there is no anticipated impact on function. The aim of this study was to review the long term functional, cosmetic and psychosocial outcomes in men with uncorrected hypospadias. This information may be helpful for parents who are burdened with deciding the correct treatment for their child's hypospadias.

Methods

A scoping review of PubMed, EMBASE, and CINAHL + databases was performed in adherence with PRISMA guidelines. Eight studies were identified for inclusion in the review.

Results

Men with mild uncorrected hypospadias have similar functional outcomes to those without hypospadias, preferring to void standing and reporting similar IPSS scores. However, those with severe untreated hypospadias experience significant urinary difficulties, higher IPSS scores, and are more likely to sit when voiding. They reported worse SHIM scores, more ventral curvature, and greater difficulty with intercourse. Most men with incidentally identified hypospadias are unaware of their condition and are satisfied with their penile appearance. There was no difference in the attainment of psychosocial milestones between men with uncorrected hypospadias versus no hypospadias.

Conclusion

There is a lack of research regarding the experiences of adult men with uncorrected hypospadias. However, there is some evidence to support the non-operative management of mild hypospadias. Therefore, the decision to defer surgery in infancy should balance parental wishes and physician guidance, particularly in cases where the risk of functional impairment is low.
导言:尿道下裂修复术的目的是优化排尿和性功能,改善外观,尽量减少阴茎畸形带来的社会心理影响。然而,在尿道下裂程度较轻、畸形不明显且预计不会影响功能的情况下,手术的作用尚不明确。本研究旨在回顾尿道下裂未矫正男性的长期功能、外观和社会心理影响。这些信息可能对那些为决定如何正确治疗尿道下裂而烦恼的父母有所帮助:方法:根据 PRISMA 指南,对 PubMed、EMBASE 和 CINAHL + 数据库进行了范围审查。结果:患有轻度尿道下裂而未矫正的男性,其尿道下裂程度较轻:结果:患有轻度未矫正尿道下裂的男性与无尿道下裂的男性具有相似的功能结果,他们更喜欢站立排尿,并报告了相似的IPSS评分。然而,那些患有严重尿道下裂且未得到治疗的患者会出现严重的排尿困难,IPSS评分较高,排尿时更倾向于坐着。他们的SHIM评分更差,腹侧弯曲更多,性交困难更大。大多数意外发现尿道下裂的男性并不知道自己的病情,并对自己的阴茎外观感到满意。未矫正尿道下裂的男性与未矫正尿道下裂的男性在达到社会心理里程碑方面没有差异:关于尿道下裂未矫正成年男性的经历,目前还缺乏相关研究。不过,有一些证据支持对轻度尿道下裂进行非手术治疗。因此,在决定是否推迟婴儿期手术时,应平衡父母的意愿和医生的指导,尤其是在功能障碍风险较低的情况下。
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引用次数: 0
Outcomes of bulbar artery sparing during anastomotic urethroplasty for pelvic fracture urethral injury 骨盆骨折尿道损伤吻合口尿道成形术中保留球动脉的效果。
Pub Date : 2025-01-01 DOI: 10.1016/j.acuroe.2024.11.005
R.G. Gómez, L.G. Velarde, R.A. Campos, R. Massouh, V. Humerez, V. Barrientos

Objective

To the present long-term outcomes of the vascular-sparing approach during reconstruction of pelvic fracture urethral injuries (PFUI) described by Gomez et al.

Material and methods

Anastomotic reconstruction of PFUI is performed without transecting the bulb of the spongiosum, to preserve the antegrade flow of the bulbar arteries. After exposure of the urethra, the bulbar arteries are located using a Doppler stethoscope. The bulb is mobilized dorsally and unilaterally, sacrificing the artery with the weaker Doppler signal to preserve the best contralateral artery. Occasionally, both arteries can be preserved. Removal of all fibrosis and anastomosis is performed as described in the traditional transecting technique.

Results

A total of 60 patients were included, with a mean age of 37 years (IQR 22–48). The median time from trauma to urethral reconstruction was 16 weeks, and the mean stenosis length was 2.5 cm (IQR 2–3). The left bulbar artery was preserved in 27 cases, the right bulbar artery in 8, and both in 24. There were postoperative complications in 14 cases (23%), but only one of them was Clavien ≥ III. With a mean follow-up of 56 months (IQR 12–87), only one patient failed due to stenosis (98% success).

Conclusion

Preservation of antegrade arterial flow to the corpus spongiosum during PFUI reconstruction is feasible and safe. Although slightly more elaborate, this technique could reduce the risk of ischemic failure of reconstruction.
目的:探讨Gomez等报道的骨盆骨折尿道损伤(PFUI)重建中血管保留入路的远期疗效。材料和方法:吻合重建的PFUI不横切海绵球,以保持球囊动脉的顺行流动。暴露尿道后,用多普勒听诊器定位球动脉。球茎向背侧单侧移动,牺牲多普勒信号较弱的动脉以保留最佳对侧动脉。偶尔,两条动脉都可以保留。按照传统的横切技术切除所有的纤维化并进行吻合。结果:共纳入60例患者,平均年龄37岁(IQR 22-48)。从创伤到尿道重建的中位时间为16周,平均狭窄长度为2.5 cm (IQR 2-3)。左侧球动脉保留27例,右侧球动脉保留8例,两者均保留24例。术后出现并发症14例(23%),但Clavien≥III级患者仅有1例。平均随访56个月(IQR 12-87),仅有1例患者因狭窄而失败(成功率98%)。结论:在PFUI重建过程中保留海绵体顺行动脉血流是可行和安全的。虽然稍微复杂一些,但这项技术可以降低缺血性重建失败的风险。
{"title":"Outcomes of bulbar artery sparing during anastomotic urethroplasty for pelvic fracture urethral injury","authors":"R.G. Gómez,&nbsp;L.G. Velarde,&nbsp;R.A. Campos,&nbsp;R. Massouh,&nbsp;V. Humerez,&nbsp;V. Barrientos","doi":"10.1016/j.acuroe.2024.11.005","DOIUrl":"10.1016/j.acuroe.2024.11.005","url":null,"abstract":"<div><h3>Objective</h3><div>To the present long-term outcomes of the vascular-sparing approach during reconstruction of pelvic fracture urethral injuries (PFUI) described by Gomez et al.</div></div><div><h3>Material and methods</h3><div>Anastomotic reconstruction of PFUI is performed without transecting the bulb of the spongiosum, to preserve the antegrade flow of the bulbar arteries. After exposure of the urethra, the bulbar arteries are located using a Doppler stethoscope. The bulb is mobilized dorsally and unilaterally, sacrificing the artery with the weaker Doppler signal to preserve the best contralateral artery. Occasionally, both arteries can be preserved. Removal of all fibrosis and anastomosis is performed as described in the traditional transecting technique.</div></div><div><h3>Results</h3><div>A total of 60 patients were included, with a mean age of 37 years (IQR 22–48). The median time from trauma to urethral reconstruction was 16 weeks, and the mean stenosis length was 2.5 cm (IQR 2–3). The left bulbar artery was preserved in 27 cases, the right bulbar artery in 8, and both in 24. There were postoperative complications in 14 cases (23%), but only one of them was Clavien ≥ III. With a mean follow-up of 56 months (IQR 12–87), only one patient failed due to stenosis (98% success).</div></div><div><h3>Conclusion</h3><div>Preservation of antegrade arterial flow to the corpus spongiosum during PFUI reconstruction is feasible and safe. Although slightly more elaborate, this technique could reduce the risk of ischemic failure of reconstruction.</div></div>","PeriodicalId":94291,"journal":{"name":"Actas urologicas espanolas","volume":"49 1","pages":"Pages 102-107"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142776183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of anastomotic strictures after phalloplasty: An up-to-date review of the literature 阴茎成形术后吻合口狭窄的治疗:最新文献综述。
Pub Date : 2025-01-01 DOI: 10.1016/j.acuroe.2024.11.001
W. Verla , N. Lumen , M. Waterloos , J. Adamowicz , F. Campos-Juanatey , A. Cocci , M. Frankiewicz , G. Mantica , C. Rosenbaum , F.X. Madec , E. Redmond , Ł. Białek , F. Chierigo , M. Oszczudłowski , M. Vetterlein , en representación del Grupo de Trabajo de Urología Reconstructiva y Trauma Urológico de la Sección de Jóvenes Urólogos Académicos - Asociación Europea de Urología

Introduction

Neo-urethral stricture formation frequently occurs after phalloplasty and most commonly affects the anastomosis between the fixed and phallic part of the neo-urethra. This narrative review gives an overview of the existing literature on how to treat these particular strictures.

Methods

This narrative review is based on a literature search conducted in June 2024. No restrictions in terms of publication date, language or sample size were applied.

Results

Treatment options include direct vision internal urethrotomy, anastomotic repair urethroplasty, augmentation urethroplasty with grafts or flaps, multi-stage urethroplasty and urethrostomy. Overall, outcomes of these treatments are worse in transmen than in cismen, mainly due to the specific challenges posed by the neophallus environment. Generally, limited data are available on the treatment options for patients with anastomotic strictures after phalloplasty and, consequently, no clear recommendations can be made.

Conclusion

This narrative review provides a comprehensive and up-to-date overview of the available literature, which may guide future research and help optimize the outcomes for patients with this complex problem after phalloplasty.
前言:新尿道狭窄是阴茎成形术后常见的现象,最常影响新尿道固定部分与阴茎部分的吻合。这篇叙事性的评论概述了现有的关于如何治疗这些特殊的狭窄的文献。方法:本文基于2024年6月进行的文献检索。在出版日期、语言或样本量方面没有限制。结果:治疗方案包括直接目视内尿道切开术、吻合口修复尿道成形术、移植或皮瓣尿道扩张成形术、多期尿道成形术和尿道造口术。总的来说,这些治疗的结果在男性中比在男性中更差,主要是由于新生儿环境带来的特殊挑战。一般来说,关于阴茎成形术后吻合口狭窄患者的治疗选择的资料有限,因此无法提出明确的建议。结论:本文对现有文献进行了全面和最新的综述,可以指导未来的研究,并有助于优化阴茎成形术后这一复杂问题患者的预后。
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引用次数: 0
Long-term functional success and patient-reported outcomes after female one-stage buccal mucosal graft urethroplasty 女性一期口腔粘膜移植尿道成形术后的长期功能成功率和患者报告结果。
Pub Date : 2025-01-01 DOI: 10.1016/j.acuroe.2024.05.014
J. Klemm, P. Marks, R.J. Schulz, D.K. Filipas, D.R. Stelzl, R. Dahlem, M. Fisch, M.W. Vetterlein, on behalf of the Trauma and Reconstructive Urology Working Party of the European Association of Urology Young Academic Urologists

Introduction and objectives

Female urethral strictures are a rare condition that significantly impacts patients’ quality of life. Patient-reported outcomes are crucial, yet data regarding sexual function and treatment satisfaction are scarce. We aimed to provide insights from a reconstructive referral center.

Patients and methods

We conducted a retrospective analysis of women treated with ventral onlay one-stage buccal mucosa graft urethroplasty for urethral strictures between 2009–2023. We assessed objective (retreatment-free survival, ΔQmax) and subjective outcomes (validated patient-reported outcomes).

Results

Of 12 women, 83% and 17% had iatrogenic and idiopathic strictures, respectively. Median number of prior interventions was 6. Strictures were located meatal and mid-urethral in 25% and 75%, respectively, 22% had the bladder neck involved. Median graft length was 2 cm. At median follow-up of 66 months, 33% of patients underwent stricture retreatment, but only one case occurred within the first 2 years postoperatively. The median improvement in maximum flow rate (ΔQmax) was 10 ml/s. Median International Consultation on Incontinence Questionnaire Female Lower Urinary Tract Symptoms Modules (ICIQ-FLUTS) scores were 8 for filling symptoms, 6 for voiding symptoms, and 3 for incontinence symptoms. Median ICIQ-FLUTSsex score was 4. Higher scores indicate a higher symptom burden. Median ICIQ-Satisfaction outcome and satisfaction scores were 18 and 7, respectively, reflecting high treatment satisfaction.

Conclusions

Buccal mucosal graft urethroplasty by ventral onlay for female urethral strictures yields effective, durable, and positively received outcomes. However, larger studies across multiple institutions are necessary to further assess its efficacy, especially regarding patient-reported experiences and sexual function.
引言和目的:女性尿道狭窄是一种严重影响患者生活质量的罕见疾病。患者报告的结果至关重要,但有关性功能和治疗满意度的数据却很少。我们的目的是提供一个整形转诊中心的见解:我们对 2009-2023 年间接受腹侧嵌顿一期颊粘膜移植尿道成形术治疗尿道狭窄的女性进行了回顾性分析。我们评估了客观结果(无再治疗生存率、ΔQmax)和主观结果(有效的患者报告结果):12名女性中,83%和17%分别患有先天性和特发性狭窄。25%和75%的狭窄分别位于肉腔和尿道中段,22%的狭窄涉及膀胱颈。移植物的中位长度为 2 厘米。中位随访时间为 66 个月,33% 的患者接受了狭窄再治疗,但只有一例发生在术后两年内。最大流速(ΔQmax)的中位改善率为 10 毫升/秒。国际尿失禁咨询问卷女性下尿路症状模块(ICIQ-FLUTS)评分中位数为:充盈症状 8 分,排尿症状 6 分,尿失禁症状 3 分。ICIQ-FLUTSsex 的中位数为 4 分,分数越高,症状负担越重。ICIQ-满意度结果和满意度得分的中位数分别为18分和7分,反映了治疗的高满意度:颊粘膜移植尿道成形术通过腹侧嵌顿治疗女性尿道狭窄可获得有效、持久和积极的疗效。然而,有必要在多个机构开展更大规模的研究,以进一步评估其疗效,尤其是在患者报告的经历和性功能方面。
{"title":"Long-term functional success and patient-reported outcomes after female one-stage buccal mucosal graft urethroplasty","authors":"J. Klemm,&nbsp;P. Marks,&nbsp;R.J. Schulz,&nbsp;D.K. Filipas,&nbsp;D.R. Stelzl,&nbsp;R. Dahlem,&nbsp;M. Fisch,&nbsp;M.W. Vetterlein,&nbsp;on behalf of the Trauma and Reconstructive Urology Working Party of the European Association of Urology Young Academic Urologists","doi":"10.1016/j.acuroe.2024.05.014","DOIUrl":"10.1016/j.acuroe.2024.05.014","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Female urethral strictures are a rare condition that significantly impacts patients’ quality of life. Patient-reported outcomes are crucial, yet data regarding sexual function and treatment satisfaction are scarce. We aimed to provide insights from a reconstructive referral center.</div></div><div><h3>Patients and methods</h3><div>We conducted a retrospective analysis of women treated with ventral onlay one-stage buccal mucosa graft urethroplasty for urethral strictures between 2009–2023. We assessed objective (retreatment-free survival, ΔQmax) and subjective outcomes (validated patient-reported outcomes).</div></div><div><h3>Results</h3><div>Of 12 women, 83% and 17% had iatrogenic and idiopathic strictures, respectively. Median number of prior interventions was 6. Strictures were located meatal and mid-urethral in 25% and 75%, respectively, 22% had the bladder neck involved. Median graft length was 2 cm. At median follow-up of 66 months, 33% of patients underwent stricture retreatment, but only one case occurred within the first 2 years postoperatively. The median improvement in maximum flow rate (ΔQmax) was 10 ml/s. Median International Consultation on Incontinence Questionnaire Female Lower Urinary Tract Symptoms Modules (ICIQ-FLUTS) scores were 8 for filling symptoms, 6 for voiding symptoms, and 3 for incontinence symptoms. Median ICIQ-FLUTSsex score was 4. Higher scores indicate a higher symptom burden. Median ICIQ-Satisfaction outcome and satisfaction scores were 18 and 7, respectively, reflecting high treatment satisfaction.</div></div><div><h3>Conclusions</h3><div>Buccal mucosal graft urethroplasty by ventral onlay for female urethral strictures yields effective, durable, and positively received outcomes. However, larger studies across multiple institutions are necessary to further assess its efficacy, especially regarding patient-reported experiences and sexual function.</div></div>","PeriodicalId":94291,"journal":{"name":"Actas urologicas espanolas","volume":"49 1","pages":"Pages 72-79"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140961420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oral care pathways after oral mucosal graft harvesting: a systematic review 口腔粘膜移植收获后的口腔护理途径:系统综述。
Pub Date : 2025-01-01 DOI: 10.1016/j.acuroe.2024.11.002
M. Frankiewicz , J. Adamowicz , L. Białek , F. Campos-Juanatey , F. Chierigo , A. Cocci , F.X. Madec , G. Mantica , M. Oszczudłowski , E.J. Redmond , C.M. Rosenbaum , W. Verla , M. Waterloos , M. Jobczyk , A. Kałużny , M.W. Vetterlein , M. Matuszewski , on behalf of the Trauma and Reconstructive Urology Working Party of the European Association of Urology Young Academic Urologists

Introduction

Oral mucosal grafts are essential in reconstructive urology, particularly for urethral and genital defects. Advances in harvesting and implantation techniques have been made, yet perioperative care remains crucial for optimal outcomes. This systematic review explores postoperative care pathways following oral mucosal graft harvesting to consolidate knowledge, identify best practices, and highlight research gaps.

Objective

The review aims to identify optimal care pathways, compare different oral care approaches, and address research gaps.

Methods

A systematic literature search was conducted using PubMed, Scopus, and Web of Science databases without time constraints. Key search terms included “oral mucosal graft”, “oral care pathways”, “OMG post-operative care”, “BMG”, “LMG”, and “OMG graft harvesting”. Selection followed PRISMA guidelines. Inclusion criteria focused on studies addressing oral mucosal grafts in reconstructive urology and associated perioperative care, excluding non-English articles, case reports, and editorials.

Results

The review underscores the suitability of oral mucosa for grafting due to properties like excellent vascularization and minimal immunogenicity. Comparisons among graft harvesting sites reveal differences in tissue quality, ease of harvest, and donor site morbidity. Non-closure techniques generally result in less postoperative pain and quicker healing, though closure might better control bleeding and infection. Despite common complications such as mild trismus and altered chewing efficiency, patient satisfaction remains high.

Conclusions

Effective management of oral mucosal grafts harvesting emphasizes tailored perioperative care to minimize complications and enhance recovery. Further research should focus on long-term oral morbidity, standardized care protocols, and patient-reported outcomes to improve care pathways and surgical results.
口腔粘膜移植在泌尿外科重建中是必不可少的,特别是对于尿道和生殖器缺陷。收获和植入技术已经取得进展,但围手术期护理仍然是最佳结果的关键。本系统综述探讨了口腔粘膜移植物收获后的术后护理途径,以巩固知识,确定最佳做法,并突出研究空白。目的:本综述旨在确定最佳的口腔护理途径,比较不同的口腔护理方法,并解决研究空白。方法:在不受时间限制的情况下,利用PubMed、Scopus和Web of Science数据库进行系统文献检索。关键搜索词包括“口腔黏膜移植”、“口腔护理途径”、“OMG术后护理”、“BMG”、“LMG”和“OMG移植收获”。选择遵循PRISMA指南。纳入标准集中于口腔黏膜移植在泌尿外科重建及相关围手术期护理方面的研究,不包括非英文文章、病例报告和社论。结果:本综述强调口腔黏膜具有良好的血管化和最小的免疫原性等特性,适合移植。在移植收获地点之间的比较揭示了组织质量、收获难易程度和供体部位发病率的差异。非闭合技术通常会减少术后疼痛和更快愈合,尽管闭合可能会更好地控制出血和感染。尽管常见的并发症,如轻度牙关和咀嚼效率的改变,患者的满意度仍然很高。结论:口腔粘膜移植的有效管理强调围手术期护理,以减少并发症,提高康复。进一步的研究应侧重于长期口腔发病率、标准化护理方案和患者报告的结果,以改善护理途径和手术结果。
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引用次数: 0
History of urethral surgery: Lessons learnt from the past 尿道手术的历史:从过去吸取的教训。
Pub Date : 2025-01-01 DOI: 10.1016/j.acuroe.2024.12.003
F.X. Madec , P. Neuville , F. Chierigo , J. Adamowicz , Ł. Białek , A. Cocci , M. Frankiewicz , G. Mantica , M. Oszczudłowski , E.J. Redmond , C.M. Rosenbaum , W. Verla , M. Waterloos , F. Campos-Juanatey , J. Klemm , M. Vetterlein , on behalf of the Grupo de Trabajo de Urología Reconstructiva y Trauma Urológico de la Sección de Jóvenes Urólogos Académicos - Asociación Europea de Urología

Introduction

Although failures are undesirable, they offer valuable learning opportunities that drive progress through necessary changes. This concept holds particularly true in the history of urethral reconstruction.

Methods

A comprehensive literature review was conducted using PubMed, focusing on the history of the urethral stricture and current trends based on national and international guidelines for urethral stricture management.

Results

Urethral strictures are among the oldest known urological conditions, with initial treatments centred around dilatation. These palliative measures proved disappointing. The advent of reconstructive urology has transformed this pathology into a treatable condition, notably through Excision and Primary Anastomosis (EPA) and one-stage augmentation urethroplasty using buccal grafts.

Conclusion

Urethroplasty is the gold standard treatment for urethral strictures, and ongoing refinements aim to further reduce morbidity.
虽然失败是不受欢迎的,但它们提供了宝贵的学习机会,通过必要的改变推动进步。这个概念在尿道重建的历史上尤其正确。方法:结合国内外尿道狭窄治疗指南,在PubMed上进行文献综述,重点分析尿道狭窄的历史和发展趋势。结果:尿道狭窄是已知的最古老的泌尿系统疾病之一,最初的治疗以扩张为中心。事实证明,这些缓和措施令人失望。重建泌尿外科的出现已经将这种病理转变为一种可治疗的疾病,特别是通过切除和初级吻合(EPA)和一期增强尿道成形术使用颊移植物。结论:尿道成形术是尿道狭窄的金标准治疗方法,并不断改进以进一步降低发病率。
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引用次数: 0
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Actas urologicas espanolas
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