Current research in parasitology & vector-borne diseases最新文献

{"title":"Monitoring of questing tick species distribution in Galicia, north-western Spain, over a period of 5.5 years","authors":"María Vilá Pena ,&nbsp;Inês Abreu Ramos ,&nbsp;Génesis Bautista García ,&nbsp;Elvira Íñiguez Pichel ,&nbsp;Cristiana Cazapal Monteiro ,&nbsp;José Ángel Hernández Malagón ,&nbsp;Adolfo Paz Silva ,&nbsp;Rita Sánchez-Andrade Fernández ,&nbsp;María Sol Arias Vázquez","doi":"10.1016/j.crpvbd.2025.100254","DOIUrl":"10.1016/j.crpvbd.2025.100254","url":null,"abstract":"<div><div>An active survey was performed by the Galician Vector Surveillance Network (ReGaViVec) to determine the distribution of questing tick species in the Autonomous Community of Galicia Galicia, north-western Spain. Monitoring of tick populations involved drag/flag sampling at 533 locations over a period of 5.5 years. The identification of tick species, sex, and stage was carried out according to morphological keys, and the results were analyzed considering three Köppen climate regions, i.e. Cfb (marine west coast climate), Csb (warm-summer Mediterranean climate), and Csa (hot-summer Mediterranean climate), season, environment (forest, rural, or urban), vegetation height (≤ 15 cm, 16–40 cm, and &gt; 40 cm); and altitude (&lt; 300 m, 301–500 m, 501–1000 m, and &gt;1000 m). A total of 1378 ticks were collected at 260 locations: 62.92% in Csb, 24.38% in Cfb, and 12.70% in Csa. Of these, 2% were larvae, 45.2% were nymphs, and 52.8% were adults (58.3% females and 41.7% males). Six species were recorded, i.e. <em>Ixodes ricinus</em> (57.90%), <em>Rhipicephalus sanguineus</em> (<em>sensu lato</em>) (26.05%), <em>Dermacentor reticulatus</em> (10.95%), <em>Dermacentor marginatus</em> (2.10%), <em>Haemaphysalis</em> sp. (2.61%), and <em>Rhipicephalus bursa</em> (0.36%). A seasonal pattern was recorded, with the relative abundance of <em>I. ricinus</em> and <em>R. sanguineus</em> (<em>s.l</em>.) peaking in spring-summer, and that of <em>Dermacentor</em> spp. and <em>Haemaphysalis</em> sp. peaking in autumn-winter. Significant differences were demonstrated in the species abundance distribution according to climate region, season, environment, and altitude. The highest tick abundance was recorded in summer, in rural areas, and at altitudes of &lt; 300 m. Because most of the tick species present in the environment of Galicia have vectorial competence for emerging tick-borne pathogens, it is important to maintain research and coordination of tick surveillance practices in the region.</div></div>","PeriodicalId":94311,"journal":{"name":"Current research in parasitology & vector-borne diseases","volume":"7 ","pages":"Article 100254"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143785288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of seasonal change on virus-rodent dynamics in Nigeria’s Edo-Ondo hotspot for Lassa fever","authors":"Akinlabi Oyeyiola ,&nbsp;Adetunji Samuel Adesina ,&nbsp;Adeoba Obadare ,&nbsp;Joseph Igbokwe ,&nbsp;Samuel Ayobami Fasogbon ,&nbsp;Chukwuyem Abejegah ,&nbsp;Patience Akhilomen ,&nbsp;Danny Asogun ,&nbsp;Ekaete Tobin ,&nbsp;Olufemi Ayodeji ,&nbsp;Omolaja Osoniyi ,&nbsp;Meike Pahlmann ,&nbsp;Stephan Günther ,&nbsp;Elisabeth Fichet-Calvet ,&nbsp;Ayodeji Olayemi","doi":"10.1016/j.crpvbd.2025.100271","DOIUrl":"10.1016/j.crpvbd.2025.100271","url":null,"abstract":"<div><div>The zoonotic Lassa virus (LASV) is naturally maintained in rodents but commonly virulent in humans, killing thousands across West Africa annually. Human cases of Lassa fever surge during the dry season. In a hotspot for this disease, involving seven localities from Edo and Ondo states within Nigeria, we sought to depict how fluctuation patterns of LASV prevalence in rodents and levels of rodent infestation culminate in particularly heightened points of potential rodent-to-human transmission. We also explored how this variability may be driven by environmental and demographic factors. We determined active LASV infection by PCR and previous infection using an indirect immunofluorescence assay for IgG antibodies. Six out of the seven localities had active LASV infections, ranging between 3.7% (1/27) and 75.5% (37/49). In Ebudin and Ekpoma, where longitudinal sampling was conducted, prevalence differences were not statistically significant across locality, habitat, season, or year. Conversely, abundance peaked significantly indoors for <em>Mastomys natalensis</em> (the major LASV reservoir) and <em>Praomys daltoni</em> either during the dry or rainy season, depending on whether each of these rodent species occupied Ebudin or Ekpoma. Our results suggest that, since LASV occurrence is usually widespread in its natural reservoir within highly endemic areas, a more immediate component of zoonotic risk to prioritize for control would be the targeting of rodent infestation peaks when they occur inside human habitations. Over our two-year survey, these peaks in abundance were consistent in the months they occurred yearly for <em>M. natalensis</em> and <em>P. daltoni</em> per locality.</div></div>","PeriodicalId":94311,"journal":{"name":"Current research in parasitology & vector-borne diseases","volume":"7 ","pages":"Article 100271"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144105567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Midichloria mitochondrii stimulates the sylvatic cycle of Borrelia burgdorferi (sensu lato) in Ixodes ricinus and contributes to Lyme disease risk","authors":"Clara F. Köhler ,&nbsp;Maya L. Holding ,&nbsp;Manoj Fonville ,&nbsp;Ron P. Dirks ,&nbsp;Hans J. Jansen ,&nbsp;Sara Moutailler ,&nbsp;Aurélie Heckmann ,&nbsp;Jens Zarka ,&nbsp;Erik Matthysen ,&nbsp;Hein Sprong ,&nbsp;Aleksandra I. Krawczyk","doi":"10.1016/j.crpvbd.2025.100290","DOIUrl":"10.1016/j.crpvbd.2025.100290","url":null,"abstract":"<div><div>Sex and symbionts of arthropod vectors are potential modulators of infection with vector-borne pathogens. Here, we investigated the involvement of sex and presence of the bacterial symbiont <em>Midichloria mitochondrii</em> in immature stages of <em>Ixodes ricinus</em> ticks on the acquisition and abundance of the tick-borne spirochete <em>Borrelia burgdorferi</em> (<em>sensu lato</em>). There was no difference in the infection rate of <em>M. mitochondrii</em> between male and female larvae. The infection with <em>M. mitochondrii</em> but not tick sex increased the acquisition of <em>B. burgdorferi</em> (<em>s.l.</em>) by <em>I. ricinus</em> larvae feeding on naturally infected birds. The infection with <em>B. burgdorferi</em> (<em>s.l.</em>) in questing nymphs was positively associated with <em>M. mitochondrii</em>, but not with their sex. The infection rates of <em>M. mitochondrii</em> in field-collected ticks showed substantial spatial variation. In our field study, we observed that locations exhibiting higher <em>M. mitochondrii</em> prevalence in nymphs also have significantly higher infection rates with <em>B. burgdorferi</em> (<em>s.l.</em>). Thus, the <em>M. mitochondrii</em> symbiont appears to enhance the ability of immature <em>I. ricinus</em> ticks to acquire and/or maintain <em>B. burgdorferi</em> (<em>s.l.</em>) in nature and is therefore an additional factor that contributes to the spatial variation in Lyme disease risk.</div></div>","PeriodicalId":94311,"journal":{"name":"Current research in parasitology & vector-borne diseases","volume":"8 ","pages":"Article 100290"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144581268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cryptosporidium in cattle: Assessing the zoonotic risk","authors":"Sugandika Bulumulla ,&nbsp;Lihua Xiao ,&nbsp;Yaoyu Feng ,&nbsp;Amanda Ash ,&nbsp;Joshua Aleri ,&nbsp;Una Ryan ,&nbsp;Amanda D. Barbosa","doi":"10.1016/j.crpvbd.2025.100279","DOIUrl":"10.1016/j.crpvbd.2025.100279","url":null,"abstract":"<div><div>Cattle infected with <em>Cryptosporidium</em> can shed large quantities of the environmentally resistant oocysts<em>,</em> which can cause significant diarrhoeal disease, particularly in neonatal calves and in susceptible human populations worldwide. More than ten species of <em>Cryptosporidium</em> have been reported in cattle; however, <em>C. parvum</em> dominates in young calves in many countries, with <em>C. ryanae</em>, <em>C. bovis</em> and <em>C. andersoni</em> prevalent in older animals. <em>Cryptosporidium hominis</em> and <em>C. parvum</em> are the main species infecting humans. In most countries, zoonotic cryptosporidiosis is primarily caused by <em>C. parvum</em> IIa subtypes, which also dominates in calves, but in China, <em>C. parvum</em> infections in cattle are exclusively caused by IId subtypes. Outbreak investigations and molecular epidemiological studies support calves as a major source of zoonotic cryptosporidiosis. The zoonotic significance of increasing reports of <em>C. hominis</em> in cattle requires further investigation. Epidemiological investigations designed to better understand the sources and transmission dynamics using improved typing tools are required before better control strategies can be implemented.</div></div>","PeriodicalId":94311,"journal":{"name":"Current research in parasitology & vector-borne diseases","volume":"8 ","pages":"Article 100279"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144366616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"European human granulocytic anaplasmosis is caused by a subcluster of Anaplasma phagocytophilum Ecotype I","authors":"Paulina M. Lesiczka ,&nbsp;Friederike D. von Loewenich ,&nbsp;Robert Kohl ,&nbsp;Aleksandra I. Krawczyk ,&nbsp;Ron P. Dirks ,&nbsp;Pierre H. Boyer ,&nbsp;Benoît Jaulhac ,&nbsp;Anna Moniuszko-Malinowska ,&nbsp;Tina Uršič ,&nbsp;Franc Strle ,&nbsp;Stanka Lotrič-Furlan ,&nbsp;Tatjana Avšič-Županc ,&nbsp;Miroslav Petrovec ,&nbsp;Hein Sprong","doi":"10.1016/j.crpvbd.2025.100324","DOIUrl":"10.1016/j.crpvbd.2025.100324","url":null,"abstract":"<div><div><em>Anaplasma phagocytophilum</em> causes human granulocytic anaplasmosis. However, despite its ubiquitous presence in animals and ticks, human cases are rarely reported in Europe. We generated genetic data from <em>A. phagocytophilum</em> from patients and compared them with sequences from wild and domestic animals to assess the zoonotic potential of the respective genotypes. The genomic sequence of an <em>A. phagocytophilum</em> isolate obtained from a Slovenian patient was determined. We also sequenced a <em>groEL</em>-gene fragment of eight isolates from human patients from France and Poland. The <em>A. phagocytophilum</em> genome from the Slovenian patient was more closely related to isolates from dogs than from sheep. Using <em>groEL</em>-based typing, isolates from humans were found within a distinct subcluster of <em>A. phagocytophilum</em> Ecotype I. This subcluster was defined as zoonotic. Strains from dogs, horses, cats, foxes, wolves, and wild boar were significantly overrepresented in this branch. Variants outside this subcluster were more abundant and found in a wider variety of domestic and wild animals, most notably ruminants. A similar pattern was observed for the MLST analyses targeting seven housekeeping genes. Human anaplasmosis in Europe is associated with a specific subcluster of <em>A. phagocytophilum</em> Ecotype I, which is not primarily associated with ruminants, but rather with dogs, horses, cats, carnivores, wild boar and hedgehogs. Our findings provide a reasonable explanation for the discrepancy between the omnipresence of <em>A. phagocytophilum</em> in the environment and the limited number of reported human cases. We recommend taking this genetic sub-clustering into account for future risk assessments.</div></div>","PeriodicalId":94311,"journal":{"name":"Current research in parasitology & vector-borne diseases","volume":"8 ","pages":"Article 100324"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145265380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Occurrence and the first molecular genotyping of Dibothriocephalus dendriticus and Dibothriocephalus ditremus (Cestoda: Diphyllobothriidea) in salmonids from Iceland","authors":"Ivica Králová-Hromadová ,&nbsp;Eva Čisovská Bazsalovicsová ,&nbsp;Alžbeta Radačovská ,&nbsp;Lucia Dinisová ,&nbsp;Karl Skírnisson","doi":"10.1016/j.crpvbd.2025.100301","DOIUrl":"10.1016/j.crpvbd.2025.100301","url":null,"abstract":"<div><div>The occurrence of <em>Dibothriocephalus dendriticus</em> and <em>Dibothriocephalus ditremus</em> (Cestoda: Diphyllobothriidea) in salmonids from lakes Hafravatn, Thingvallavatn, Másvatn, and Ytra-Hólavatn in Iceland was studied. The exact taxonomic identification of plerocercoids was performed by a recently validated molecular discriminatory PCR-based approach using <em>D. dendriticus</em>-specific Dd_8 primers. Of 1684 plerocercoids isolated from 58 fish (40 Arctic charrs <em>Salvelinus alpinus</em>, and 18 brown trout <em>Salmo trutta</em>), 318 (18.9%) larvae were identified as <em>D. dendriticus</em> and 1366 (81.1%) as <em>D. ditremus</em>. The prevalence of <em>D. ditremus</em> was high at all four localities, ranging from 54.2% to 100%. Similarly, the prevalence of <em>D. dendriticus</em> ranged from 50.0% to 100% in all lakes, except for Ytra-Hólavatn, where a prevalence of 14.3% was recorded. All examined specimens of large benthivorous (LB) charr from Thingvallavatn were negative, which was related to the specific habitat and the different feeding specialization of the LB morph. In contrast, the prevalence and the intensity of infection with both <em>D. dendriticus</em> and <em>D. ditremus</em> were high in piscivorous and planktivorous Arctic charr morphs. The intensity of infection with <em>D. dendriticus</em> was lower in all four lakes compared to much higher values detected for <em>D. ditremus.</em> The relative abundance of <em>D. dendriticus</em> and <em>D. ditremus</em> plerocercoids in individual fish hosts showed substantially lower values for <em>D. dendriticus</em> in all four lakes. This can be explained by various climatic conditions required for egg development and by the different feeding ecology of aquatic birds, definitive hosts of both tapeworms.</div></div>","PeriodicalId":94311,"journal":{"name":"Current research in parasitology & vector-borne diseases","volume":"8 ","pages":"Article 100301"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144831121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serological assessment of pediatric parasite exposure in two Senegalese districts using multiplex serology","authors":"Helena Brazal Monzó ,&nbsp;Santiago Rayment Gomez ,&nbsp;Doudou Sow ,&nbsp;Aminata Colle Lo ,&nbsp;Marie Pierre Diouf ,&nbsp;Amadou Seck ,&nbsp;Ibrahima Mbaye ,&nbsp;Elhadji Babacar Fall ,&nbsp;Catriona Patterson ,&nbsp;Seyi Soremekun ,&nbsp;Isaac A. Manga ,&nbsp;Cheikh Cissé ,&nbsp;Awa Diouf ,&nbsp;Ndéye Aida Gaye ,&nbsp;Kevin K.A. Tetteh ,&nbsp;Alex Loukas ,&nbsp;Brian Greenwood ,&nbsp;Jean Louis A. Ndiaye ,&nbsp;Chris Drakeley ,&nbsp;Muhammed O. Afolabi","doi":"10.1016/j.crpvbd.2025.100320","DOIUrl":"10.1016/j.crpvbd.2025.100320","url":null,"abstract":"<div><div>Although pediatric parasitic diseases cause significant morbidity and mortality in regions with high rates of co-infection, this overlap may offer opportunities for integrated control strategies. This study aimed at a serological assessment of exposure to multiple parasitic infections among children aged 1–14 years in two Senegalese districts, Saraya (Kédougou Region) and Diourbel (Diourbel Region), to inform integrated control strategies. We analysed 883 dried blood spot samples. A multiplex bead-based immunoassay quantified IgG antibody against <em>Plasmodium falciparum</em>, helminths (<em>Necator americanus</em>, <em>Schistosoma mansoni</em>, <em>Strongyloides stercoralis</em>, <em>Taenia solium</em>), and intestinal protozoa (<em>Cryptosporidium parvum</em>, <em>Giardia duodenalis</em>) as proxies for single- and multiple-pathogen exposure. Multivariable logistic regression identified risk factors for seropositivity. Recent malaria exposure was identified in 11% of children, while 42% showed evidence of historical exposure. Helminth seroprevalence ranged between 0.1% and 7.2%, whereas <em>Cryptosporidium parvum</em> and <em>Giardia duodenalis</em> seroprevalence values were 19.0% and 7.4%, respectively. Co-exposures to malaria and other parasites ranged from 9.4% to 18.0%. School-aged children exhibited higher seroprevalence rates for historical exposure to <em>P. falciparum</em> and <em>S. stercoralis</em> compared to pre-school children, while <em>G. duodenalis</em> was more seroprevalent in pre-school children. Saraya exhibited higher seroprevalence for historical <em>P. falciparum</em> and <em>G. duodenalis</em> exposure. Rare/never handwashing before meals, shorter travel time to a water source (&lt; 10 min, likely reflecting residence near shared or surface water rather than improved household taps), and frequent contact with any waterbodies (daily/weekly) were associated with higher odds of parasite seropositivity. While seasonal malaria chemoprevention appears suitable, the low helminth seroprevalence coupled with substantial protozoan exposure suggests that current integrated interventions may require re-evaluation and enhancement.</div></div>","PeriodicalId":94311,"journal":{"name":"Current research in parasitology & vector-borne diseases","volume":"8 ","pages":"Article 100320"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145157107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":94311,"journal":{"name":"Current research in parasitology & vector-borne diseases","volume":"7 ","pages":"Article 100268"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146277519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":94311,"journal":{"name":"Current research in parasitology & vector-borne diseases","volume":"7 ","pages":"Article 100265"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146277542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":94311,"journal":{"name":"Current research in parasitology & vector-borne diseases","volume":"7 ","pages":"Article 100272"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146277544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}