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Effect of thermocycling on acetal resin versus PEEK surface hardness and flexure strength of implant-retained overdenture bars: in vitro study 热循环对乙缩醛树脂对PEEK表面硬度和抗弯强度影响的体外研究
Pub Date : 2023-10-19 DOI: 10.1186/s42269-023-01126-6
Sherihan Hanafy Salem, Ali Abdulghani AlSourori, Marwa Hassan Mostafa
Abstract Background Implant-supported mandibular overdentures with bar attachments are considered an excellent option for a completely edentulous mandible. It provides a long-lasting and reliable solution to restore function and aesthetics to the patient. Many materials can be used for the construction of bar attachments, among which are PEEK and Acetal resin materials. The choice between PEEK and Acetal bar attachments eventually depends on the application, considering factors such as load-bearing requirements, biocompatibility, adaptability, and ease of use. Methods Twelve 3D-printed edentulous mandible models each received two implants. Models were then divided into two equal groups. Group1: Six models with PEEK bars were fabricated by thermo-pressed technique while Group 2: Six models with Acetal resin bars were fabricated by thermo-pressed technique. Surface hardness and flexure strength were then evaluated and statistically analyzed before and after thermocycling. Results PEEK group revealed significant higher surface hardness than Acetal resin before and after thermocycling. Regarding flexure strength, PEEK showed an insignificant increase than Acetal before thermocycling; however, the PEEK group displayed much higher values than the Acetal group following the thermocycling, resulting in a significant difference between the two groups. Conclusions Bar made of PEEK showed more promising surface hardness and flexure strength than Acetal resin bar.
摘要:背景种植支撑下颌骨覆盖假牙被认为是治疗完全无牙下颌骨的一个很好的选择。它提供了一个持久和可靠的解决方案,以恢复功能和美观的病人。许多材料可用于棒材附件的施工,其中有PEEK和缩醛树脂材料。PEEK和缩醛棒附件之间的选择最终取决于应用,考虑诸如承重要求,生物相容性,适应性和易用性等因素。方法12个3d打印无牙下颌骨模型各植入2个种植体。然后将模型分成两组。第1组:采用热压法制备PEEK棒6只模型;第2组:采用热压法制备缩醛树脂棒6只模型。然后对热循环前后的表面硬度和抗弯强度进行评价和统计分析。结果PEEK组在热循环前后的表面硬度明显高于缩醛树脂组。在抗弯强度方面,热循环前PEEK比缩醛的提高不显著;然而,PEEK组在热循环后显示出远高于缩醛组的值,导致两组之间存在显著差异。结论PEEK棒材的表面硬度和抗弯强度均优于缩醛树脂棒材。
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引用次数: 0
Monitoring spatiotemporal changes of urban surface water based on satellite imagery and Google Earth Engine platform in Dhaka City from 1990 to 2021 1990 - 2021年基于卫星影像和Google Earth Engine平台的达卡城市地表水时空变化监测
Pub Date : 2023-10-18 DOI: 10.1186/s42269-023-01127-5
Md. Jakir Hossain, Md. Munir Mahmud, Sheikh Tawhidul Islam
Abstract Background This study focuses on Dhaka City and its impact on urban surface water. Cities, ecosystems, and agriculture need surface water. It is crucial for water resource planning and environmental preservation. The primary aim is to study how urbanization has affected surface water in Dhaka City over 30 years using satellite imagery. Methods The study analyzed three decades of urban surface water shifts using Landsat 5 TM and Landsat 8 OLI/TIRS satellite imagery and Google Earth Engine (GEE) with JavaScript code for water ratio index detection. To investigate water level changes, field observation surveys and secondary data analysis were conducted. This integrated methodology simplified surface water data extraction and analysis, making remote sensing easier and allowing cloud-based satellite data processing. Results The study demonstrates that the amount of surface water in cities is going down, from 36.23 km 2 in 1990 to 5.83 km 2 in 2021, which is an enormous decrease. This means that about 20 square kilometers, or 45 percent of the water's surface, have been lost in the last 30 years. The main reasons for the drop are unplanned expansion of cities, accelerated real estate development, and more trade and economic activities in the study area. Conclusions The GEE algorithms provide useful insights into surface water's maximum and minimum extent, enabling appropriate planning and management. These findings aid Dhaka City's water resource management and environmental protection.
本研究以达卡市及其对城市地表水的影响为研究对象。城市、生态系统和农业都需要地表水。对水资源规划和环境保护具有重要意义。主要目的是利用卫星图像研究30年来城市化如何影响达卡市的地表水。方法利用Landsat 5 TM和Landsat 8 OLI/TIRS卫星影像,利用Google Earth Engine (GEE)和JavaScript代码进行水比指数检测,分析近30年城市地表水变化。通过野外观测调查和二次资料分析,对水位变化进行了调查。这种综合方法简化了地表水数据的提取和分析,使遥感更容易,并允许基于云的卫星数据处理。结果研究表明,城市地表水总量呈下降趋势,从1990年的36.23 km 2下降到2021年的5.83 km 2,降幅巨大。这意味着在过去的30年里,大约有20平方公里或45%的水面已经消失。下降的主要原因是城市的无计划扩张,房地产开发的加速,以及研究区域的贸易和经济活动的增加。结论GEE算法提供了对地表水最大和最小范围的有用见解,可以进行适当的规划和管理。这些发现有助于达喀市的水资源管理和环境保护。
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引用次数: 0
A plagiarism paperdemic: determining plagiarism among COVID-19 articles in infectious disease journals between 2020 and 2021 一篇抄袭论文:确定2020 - 2021年传染病期刊中COVID-19文章的抄袭情况
Pub Date : 2023-10-18 DOI: 10.1186/s42269-023-01129-3
Rahma Menshawey, Esraa Menshawey, Ahmed Mitkees, Bilal A. Mahamud
Abstract Background The COVID-19 pandemic has caused drastic changes in the publishing framework which allowed for the quick review and rapid publication of manuscripts in order to quickly share vital information about this new viral pandemic to the general public and scientists. Alarms have been raised for the potential for misconduct in COVID-19 research. The purpose of this study is to determine the presence of plagiarism in COVID-19 papers across infectious disease journals. Methods COVID-19 related research and review articles published in infectious disease journals were collected. Each manuscript was optimized and uploaded to Turnitin, which is a similarity checking tool. Similarity reports were manually checked for events of true plagiarism using an 80% threshold, performed via human judgment. Results In this cross-sectional study, 41.61% ( n = 129) of manuscripts were deemed plagiarized out of a total of 310 papers that were analyzed. Plagiarism was identified in 35.07% of reviews ( n = 47), and 46.6% of original research ( n = 82). Among the plagiarized papers, the median number of copied sentences was 3 IQR 4. The highest recorded similarity report was 60%, and the highest number of copied sentences was 85. The discussion section of these articles was the most problematic area, with the average number of copied sentences in that section being 6.25 ± 10.16. The average time to judge all manuscripts was 2.45 ± 3.09 min. Among all the plagiarized papers, 72.09% belonged to papers where the similarity report was ≤ 15% ( n = 93). No significant differences were found with regards to plagiarism events among the quartiles. Conclusions Plagiarism is prevalent in COVID-19 publications. All similarity reports should be supplemented with human judgment.
背景2019冠状病毒病大流行导致出版框架发生了巨大变化,允许快速审查和快速出版手稿,以便快速向公众和科学家分享有关这种新型病毒大流行的重要信息。人们对COVID-19研究中可能存在的不当行为发出了警告。本研究的目的是确定传染病期刊上关于COVID-19的论文中是否存在抄袭。方法收集传染病杂志上发表的新冠肺炎相关研究和综述文章。每篇稿件经过优化后上传到Turnitin,这是一个相似度检查工具。通过人工判断,使用80%的阈值手动检查相似度报告中的真实剽窃事件。结果在这项横断面研究中,在310篇被分析的论文中,41.61% (n = 129)的手稿被认为是抄袭的。35.07%的评论(n = 47)和46.6%的原创研究(n = 82)存在抄袭。在被抄袭的论文中,抄袭句子数的中位数为3 IQR 4。最高记录的相似度报告为60%,最高记录的复制句子数为85。这些文章的讨论部分是问题最多的区域,该部分的平均复制句数为6.25±10.16。所有稿件的平均判断时间为2.45±3.09 min。在所有被抄袭的论文中,相似度报告≤15%的论文占72.09% (n = 93)。四分位数间的抄袭事件无显著差异。结论2019冠状病毒病出版物中存在抄袭现象。所有相似度报告都应辅以人的判断。
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引用次数: 1
Assessment of respiratory and reproductive impacts of artisanal refinery activities on male Albino Wistar rats: implications for environmental health 手工精炼活动对雄性白化Wistar大鼠呼吸和生殖影响的评估:对环境健康的影响
Pub Date : 2023-10-17 DOI: 10.1186/s42269-023-01121-x
Piety Godwill Suku, Ejikeme Ugwoha, Ochuko Felix Orikpete, Daniel Raphael Ejike Ewim
Abstract Background Artisanal petroleum refining operations have been known to produce a significant volume of air pollutants. The highest concentration of pollutants is generated during the oven heating or crude boiling phase of the operation. The major pollutant is black carbon or soot. Although these operations are widespread, especially in developing countries, the impact of exposure to emissions from artisanal refinery on both respiratory and reproductive health remains poorly understood. Objective This study is aimed to examine the effects of controlled subacute exposure to carbon soot emissions generated during the oven heating phase of the refining process, on the respiratory and reproductive systems of male albino Wistar rats. Methods To simulate the exposure conditions found in artisanal refineries, we developed a replicable fabrication of an artisanal refinery combustion system fitted with an exposure chamber for in vivo studies. 6–8 weeks old adolescent albino Wistar rats were divided into four groups (A, B, C, & D), with group A acting as the general control group and was not exposed to any carbon soot particulate matter. Group B, C, and D were exposed subacutely for four hours each day for 3, 7, 14, 21, and 28 days to varying emission concentrations. Daily exposure measurements were determined using Aeroqual Series 300 Gas Monitor, and average exposure concentration of carbon soot particulate matter (PM 2.5 ), for each exposed group were given as: (1.221 ± 0.169 mg/m 3 , 1.290 ± 0.214 mg/m 3 1.282 ± 0.235 mg/m 3 ). Animals from each group were euthanised on Day 3, 7, 14, 21, and Day 28, respectively. Tissue samples of the lungs and testis were collected for immunohistochemistry and oxidative stress analysis. Discussion /Conclusion : Cytoarchitecture of the lungs and testis via histology and immunohistochemistry, showed inflammatory cell infiltration, thickened alveolar walls, diminished alveolar spaces, hyperaemia, and bronchial epithelial hyperplasia in the lungs of Group B, C, and D animals that were exposed to soot. While cytoarchitecture of the testis revealed a distortion of the Leydig cells, vacuolations and mild vacuolations within the spermatid layer, loss of flagella, and some distortion of seminiferous tubule in the lumen. Notable increase in the mean expression and significant P -values determined by one-way analysis of variance (ANOVA), followed by Tukey’s post hoc test, were observed on Day 14–28 ( P < 0.05) for tumour-necrosis-factor alpha (TNF-α), Day 21–28 ( P < 0.001) for malondialdehyde (MDA), and Day 21 ( P < 0.001) for superoxide dismutase (SOD) expression in the lungs of each of the experimental Group (B, C, D) when compared to the control Group A. Our study provides valuable insights into the health risks associated with exposure to carbon soot particulate matter, thus underscoring the urgent need for necessary control measures to curb air pollution as a result of artisanal refinery activities.
摘要背景:众所周知,手工石油炼制作业会产生大量的空气污染物。在烘箱加热或操作的粗沸阶段产生的污染物浓度最高。主要污染物是黑碳或煤烟。虽然这些操作很普遍,特别是在发展中国家,但接触手工炼油厂排放物对呼吸和生殖健康的影响仍然知之甚少。目的研究炼制过程中受控亚急性暴露碳烟排放对雄性白化Wistar大鼠呼吸和生殖系统的影响。方法为了模拟手工炼油厂的暴露条件,我们开发了一种可复制的手工炼油厂燃烧系统,该系统配有暴露室,用于体内研究。将6 ~ 8周龄青春期白化Wistar大鼠分为A、B、C、&D), A组作为一般对照组,不接触任何碳烟颗粒物。B、C和D组每天亚急性暴露4小时,持续3、7、14、21和28天。使用Aeroqual系列300气体监测仪测定每日暴露量,每个暴露组的碳烟颗粒物(PM 2.5)平均暴露浓度为:(1.221±0.169 mg/m 3, 1.290±0.214 mg/m 3, 1.282±0.235 mg/m 3)。各组分别于第3天、第7天、第14天、第21天和第28天实施安乐死。采集肺和睾丸组织标本进行免疫组化和氧化应激分析。讨论/结论:B组、C组和D组暴露于烟灰后肺和睾丸细胞结构显示炎性细胞浸润、肺泡壁增厚、肺泡间隙缩小、充血、支气管上皮增生。睾丸细胞结构显示睾丸间质细胞变形,精细胞层内出现空泡和轻度空泡,鞭毛缺失,管腔内精小管部分变形。在第14-28天,通过单因素方差分析(ANOVA)和Tukey事后检验,观察到平均表达量显著增加,P值显著(P <0.05)肿瘤坏死因子α (TNF-α),第21-28天(P <0.001)丙二醛(MDA)和第21天(P <0.001),与对照组a相比,每个实验组(B、C、D)肺中超氧化物歧化酶(SOD)表达的差异为0.001)。我们的研究为暴露于碳烟颗粒物质相关的健康风险提供了有价值的见解,从而强调了迫切需要采取必要的控制措施来遏制手工炼油活动造成的空气污染。
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引用次数: 0
Oral isolation of Geotrichum silvicola with Geotrichum candidum from immunocompetent teenager with oral Geotrichosis signs: the first documented case report 从有口腔地毛症征像的免疫功能青少年中口服分离白土曲菌和白土曲菌:第一例文献报道
Pub Date : 2023-10-13 DOI: 10.1186/s42269-023-01128-4
Ahmed Badri Abed, Safiye Elif Korcan, Serap Titiz, Serdar Güngör, Ibrahim Erhan Gelgör
Abstract Background Oral geotrichosis is an infection caused by Geotrichum species. It is an uncommon opportunistic oral fungal infection caused mainly by Geotrichum candidum and rarely found in immunocompetent hosts . This report attempted to highlight a case of unusual geotrichosis, which requires accurate observation, as well as indicate the appropriate diagnostic methods that may contribute to eliminating the misdiagnosis of this fungal infection. Case presentation We report of unusual isolation of Geotrichum silvicola and Geotrichum candidum from the oral cavity of a 15-year-old immunocompetent female with a sign of oral geotrichosis. The isolation of Geotrichum silvicola and Geotrichum candidum was performed using Mitis Salivarius Agar. After a month of prescribing appropriate medication and improving oral hygiene, the patient showed the absence of all the signs of geotrichosis without any complaints and an improvement in overall oral health. Conclusions The isolation of Geotrichum silvicola and Geotrichum candidum from the oral cavity of an immunocompetent patient is considered an unusual and rare case that documented for the first time.
摘要背景口腔地毛病是一种由地毛虫引起的感染。这是一种罕见的机会性口腔真菌感染,主要由念珠地霉引起,在免疫正常的宿主中很少发现。本报告试图强调一个不寻常的地毛病病例,这需要准确的观察,以及指出适当的诊断方法,可能有助于消除这种真菌感染的误诊。病例介绍:我们报告了一名15岁具有口腔地毛病体征的免疫功能正常的女性口腔中罕见地分离出白土曲菌和铁皮土曲菌。采用唾液琼脂法分离了白土曲菌和铁皮土曲菌。经过一个月的适当的药物治疗和改善口腔卫生,患者表现出所有地根病的症状消失,没有任何抱怨,整体口腔健康状况有所改善。结论首次在免疫功能正常患者口腔中分离到白土曲菌和铁皮土曲菌,为罕见病例。
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引用次数: 0
Climate change implications of electronic waste: strategies for sustainable management 电子废物对气候变化的影响:可持续管理战略
Pub Date : 2023-10-13 DOI: 10.1186/s42269-023-01124-8
Akeeb Adepoju Fawole, Ochuko Felix Orikpete, Nwakamma Ninduwezuor Ehiobu, Daniel Raphael Ejike Ewim
Abstract Background This paper addresses the escalating global issue of electronic waste (e-waste), a consequence of the burgeoning demand for electronic products coupled with their transient lifespan. The rapid accumulation of e-waste is a significant concern, especially in the context of climate change, necessitating a detailed analysis of current management strategies and the development of sustainable management practices. The intricate relationship between e-waste and climate change is emphasized, illustrating how improper disposal and recycling practices substantially contribute to greenhouse gas emissions. Main body of the abstract A meticulous analysis is conducted to critique the prevailing e-waste management strategies, identifying their shortcomings and the urgent need for enhancement and globalization of these protocols. The paper argues for a fortified, universal approach to e-waste management to address the deficiencies in current methodologies. A set of strategic, sustainable solutions for e-waste management is proposed, encompassing comprehensive regulatory frameworks, advanced recycling technologies, the incorporation of eco-design principles, and the enhancement of consumer awareness. These solutions pivot around the circular economy concept, viewing waste as a valuable resource rather than a disposal predicament, thereby promoting sustainability. Short conclusion The paper concludes that a consolidated, global approach to e-waste management is imperative for addressing the proliferation of discarded electronics and is pivotal in the wider context of mitigating climate change and fostering sustainable development. It underscores the transformative potential of sustainable e-waste management, transforming a formidable challenge into an opportunity for environmental conservation, economic growth, and societal progress, emphasizing the importance of viewing e-waste management as a vehicle for sustainability.
摘要背景本文讨论了不断升级的全球电子垃圾问题(电子垃圾),这是对电子产品迅速增长的需求以及它们短暂寿命的结果。电子废物的迅速积累是一个重大问题,特别是在气候变化的背景下,需要详细分析当前的管理战略和制定可持续的管理做法。强调了电子垃圾与气候变化之间的复杂关系,说明了不适当的处理和回收做法如何极大地促进了温室气体排放。摘要:对现行的电子垃圾管理策略进行了细致的分析,指出了它们的缺点,以及迫切需要加强和全球化这些协议。这篇论文提出了一种强化的、通用的电子废物管理方法,以解决当前方法中的缺陷。提出了一套战略性的、可持续的电子废物管理解决方案,包括全面的监管框架、先进的回收技术、结合生态设计原则和提高消费者意识。这些解决方案围绕着循环经济的概念,将废物视为宝贵的资源,而不是处理的困境,从而促进可持续性。该论文的结论是,一个统一的、全球性的电子废物管理方法对于解决废弃电子产品的扩散是必不可少的,并且在减缓气候变化和促进可持续发展的更广泛背景下是关键的。它强调了可持续电子废物管理的变革潜力,将一个巨大的挑战转化为环境保护、经济增长和社会进步的机遇,强调了将电子废物管理视为可持续发展工具的重要性。
{"title":"Climate change implications of electronic waste: strategies for sustainable management","authors":"Akeeb Adepoju Fawole, Ochuko Felix Orikpete, Nwakamma Ninduwezuor Ehiobu, Daniel Raphael Ejike Ewim","doi":"10.1186/s42269-023-01124-8","DOIUrl":"https://doi.org/10.1186/s42269-023-01124-8","url":null,"abstract":"Abstract Background This paper addresses the escalating global issue of electronic waste (e-waste), a consequence of the burgeoning demand for electronic products coupled with their transient lifespan. The rapid accumulation of e-waste is a significant concern, especially in the context of climate change, necessitating a detailed analysis of current management strategies and the development of sustainable management practices. The intricate relationship between e-waste and climate change is emphasized, illustrating how improper disposal and recycling practices substantially contribute to greenhouse gas emissions. Main body of the abstract A meticulous analysis is conducted to critique the prevailing e-waste management strategies, identifying their shortcomings and the urgent need for enhancement and globalization of these protocols. The paper argues for a fortified, universal approach to e-waste management to address the deficiencies in current methodologies. A set of strategic, sustainable solutions for e-waste management is proposed, encompassing comprehensive regulatory frameworks, advanced recycling technologies, the incorporation of eco-design principles, and the enhancement of consumer awareness. These solutions pivot around the circular economy concept, viewing waste as a valuable resource rather than a disposal predicament, thereby promoting sustainability. Short conclusion The paper concludes that a consolidated, global approach to e-waste management is imperative for addressing the proliferation of discarded electronics and is pivotal in the wider context of mitigating climate change and fostering sustainable development. It underscores the transformative potential of sustainable e-waste management, transforming a formidable challenge into an opportunity for environmental conservation, economic growth, and societal progress, emphasizing the importance of viewing e-waste management as a vehicle for sustainability.","PeriodicalId":9460,"journal":{"name":"Bulletin of the National Research Centre","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135854389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The modulation of carbohydrate intake and intermittent fasting in obese Saudi women: a pilot study 沙特肥胖妇女碳水化合物摄入和间歇性禁食的调节:一项初步研究
Pub Date : 2023-10-11 DOI: 10.1186/s42269-023-01118-6
Muneerah H. Al-jammaz, Abdulrahman Al-kalifah, Nawal Abdullah Al-bader, Maha H. Al-hussain
Abstract Background In recent years, the prevalence of overweight and obesity has increased, leading to the development of various dietary interventions as potential treatments. Two popular diets are time-restricted feeding and low-carbohydrate diets, but there is limited research on the effects of combining them. This study assessed the effects of pairing an eight-hour time-restricted feeding window with a moderate-carbohydrate diet and compared to a paired eight-hour time-restricted feeding window with a regular diet. Results The study involved 52 obese women divided into three groups: the first group followed an 8 h time-restricted feeding with a moderate low-carbohydrate diet (8-hTRF+mLCD), the second group followed an 8 h time-restricted feeding with a regular diet (8-hTRF), and the third group was the control group. Both 8 h TRF+mLCD and 8 h TRF groups had a decrease in TG levels compared to the control group. The HDL levels in both TRF groups were significantly higher than the control group, while LDL levels remained statistically insignificant in both TRF groups. Conclusions This suggests that an 8 h TRF with or without mLCD can effectively treat obesity without a change in physical activity, and combining it with a low-carbohydrate diet gives better and more rapid results.
近年来,超重和肥胖的患病率有所增加,导致各种饮食干预作为潜在的治疗方法的发展。两种流行的饮食是限时饮食和低碳水化合物饮食,但关于两者结合的效果的研究有限。这项研究评估了8小时限时喂养窗口与中等碳水化合物饮食配对的效果,并将8小时限时喂养窗口与常规饮食配对进行了比较。结果将52名肥胖女性分为三组:第一组8 h限时低碳水化合物饮食(8- htrf +mLCD),第二组8 h限时正常饮食(8- htrf),第三组为对照组。与对照组相比,8 h TRF+mLCD组和8 h TRF组的TG水平均有所下降。两组患者的HDL水平均显著高于对照组,而LDL水平均无统计学意义。结论:8 h TRF伴或不伴mLCD均可在不改变运动量的情况下有效治疗肥胖,且与低碳水化合物饮食相结合效果更好、更快。
{"title":"The modulation of carbohydrate intake and intermittent fasting in obese Saudi women: a pilot study","authors":"Muneerah H. Al-jammaz, Abdulrahman Al-kalifah, Nawal Abdullah Al-bader, Maha H. Al-hussain","doi":"10.1186/s42269-023-01118-6","DOIUrl":"https://doi.org/10.1186/s42269-023-01118-6","url":null,"abstract":"Abstract Background In recent years, the prevalence of overweight and obesity has increased, leading to the development of various dietary interventions as potential treatments. Two popular diets are time-restricted feeding and low-carbohydrate diets, but there is limited research on the effects of combining them. This study assessed the effects of pairing an eight-hour time-restricted feeding window with a moderate-carbohydrate diet and compared to a paired eight-hour time-restricted feeding window with a regular diet. Results The study involved 52 obese women divided into three groups: the first group followed an 8 h time-restricted feeding with a moderate low-carbohydrate diet (8-hTRF+mLCD), the second group followed an 8 h time-restricted feeding with a regular diet (8-hTRF), and the third group was the control group. Both 8 h TRF+mLCD and 8 h TRF groups had a decrease in TG levels compared to the control group. The HDL levels in both TRF groups were significantly higher than the control group, while LDL levels remained statistically insignificant in both TRF groups. Conclusions This suggests that an 8 h TRF with or without mLCD can effectively treat obesity without a change in physical activity, and combining it with a low-carbohydrate diet gives better and more rapid results.","PeriodicalId":9460,"journal":{"name":"Bulletin of the National Research Centre","volume":"119 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136209938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Update on prevalence and antimicrobial resistance of Staphylococcus aureus and Pseudomonas aeruginosa isolated from diabetic foot ulcers in Africa: a systematic review and meta-analysis 非洲糖尿病足溃疡中分离的金黄色葡萄球菌和铜绿假单胞菌的流行率和耐药性的最新情况:一项系统综述和荟萃分析
Pub Date : 2023-10-10 DOI: 10.1186/s42269-023-01119-5
Danladi Makeri, Martin Odoki, Emmanuel Eilu, Ezera Agwu
Abstract Background Diabetes mellitus is increasing in Africa, and diabetes-related amputations exacerbated by diabetic foot infection are also prevalent with Staphylococcus aureus and Pseudomonas aeruginosa two priority pathogens playing key roles. Understanding the local epidemiology and antimicrobial resistance profiles of these dominant pathogens is crucial for appropriate antibiotic therapy. Main body of abstract This systematic review and meta-analysis aim to contribute valuable insights that can guide the management of diabetic foot ulcer-related infections in Africa by comprehensively analyzing the available literature on the prevalence and antimicrobial resistance profiles of Staphylococcus aureus and Pseudomonas aeruginosa in infected diabetic foot ulcers across Africa. We conducted a continent-based literature search utilizing PubMed and Scopus databases on June 11th, 2023, to identify studies conducted in Africa among persons with diabetic foot ulcers that reported isolating bacteria from the foot ulcers. The main concepts related to this research, “diabetic foot ulcers”, “diabetic foot infections”, “bacteria” and “Africa” were expanded with their synonyms and combined using Boolean operators (AND, OR) to formulate the final search query. The selection and inclusion of studies followed the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA). Our review revealed that approximately 4124 bacteria have been isolated from diabetic foot ulcers across 13 African countries. Staphylococcus aureus is the dominant species with a random effect pooled prevalence of 19.9% (95%CI: [16.19–23.84%]; I 2 = 88.56% [82.26–92.62%]) followed by Pseudomonas aeruginosa with 11.8% (95%CI: [8.67–15.23%]; I 2 = 89.95% [84.67–93.41%]). Methicillin-resistant Staphylococcus aureus (MRSA) pooled 12.9% (95%CI: [3.99–25.89%]; I 2 = 95.47% [93.68–96.75%]). Multidrug-resistant S.aureus and P. aeruginosa pooled prevalence is 26.4% (95%CI: [17.84–36.06%]; I 2 = 71.16% [49.34–83.58%]) and 41.8% (95%CI: [27.38–56.91%]; I 2 = 78.48% [60.80–88.18%]), respectively. Short conclusion Staphylococcus aureus dominates diabetic foot ulcer (DFU) isolates in Africa contrary to the prevailing assertion about Pseudomonas aeruginosa . However, multidrug resistance among both species is high emphasizing the need for antimicrobial stewardship and utilization of other wound management protocols such as topical silver sulfadiazine (SSD) for the duo.
背景糖尿病在非洲呈上升趋势,糖尿病足感染加重的糖尿病相关截肢也很普遍,其中金黄色葡萄球菌和铜绿假单胞菌这两种优先病原菌起着关键作用。了解这些优势病原体的当地流行病学和抗微生物药物耐药概况对于适当的抗生素治疗至关重要。本系统综述和荟萃分析旨在通过全面分析非洲糖尿病足溃疡感染中金黄色葡萄球菌和铜绿假单胞菌的流行情况和耐药概况,为指导非洲糖尿病足溃疡相关感染的管理提供有价值的见解。我们于2023年6月11日利用PubMed和Scopus数据库进行了一项基于大陆的文献检索,以确定在非洲糖尿病足溃疡患者中进行的研究,这些研究报告从足溃疡中分离出细菌。将与本研究相关的主要概念“糖尿病足溃疡”、“糖尿病足感染”、“细菌”和“非洲”与其同义词展开,并使用布尔运算符(and、OR)进行组合,形成最终的搜索查询。研究的选择和纳入遵循系统评价和荟萃分析的首选报告项目(PRISMA)。我们的综述显示,从13个非洲国家的糖尿病足溃疡中分离出大约4124种细菌。金黄色葡萄球菌为优势菌种,随机效应总患病率为19.9% (95%CI: [16.19-23.84%]);I 2 = 88.56%[82.26 ~ 92.62%]),其次为铜绿假单胞菌,占11.8% (95%CI: [8.67 ~ 15.23%];i2 = 89.95%[84.67-93.41%])。耐甲氧西林金黄色葡萄球菌(MRSA)占12.9% (95%CI: [3.99-25.89%];i2 = 95.47%[93.68-96.75%])。耐多药金黄色葡萄球菌和铜绿假单胞菌总患病率为26.4% (95%CI: [17.84 ~ 36.06%];我2 = 71.16%(49.34 - -83.58%))和41.8%(95%置信区间ci: (27.38 - -56.91%);i2 = 78.48%[60.80-88.18%])。结论金黄色葡萄球菌在非洲的糖尿病足溃疡(DFU)分离物中占主导地位,这与铜绿假单胞菌的普遍说法相反。然而,这两个物种之间的多药耐药性高度强调了抗菌药物管理和使用其他伤口管理方案的必要性,例如对这两个物种局部使用磺胺嘧啶银(SSD)。
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引用次数: 0
Smart phone-macro lens setup (SPMLS): a low-cost and portable photography device for amateur taxonomists, biodiversity researchers, and citizen enthusiasts 智能手机微距镜头设置(SPMLS):为业余分类学家,生物多样性研究人员和公民爱好者提供的低成本便携式摄影设备
Pub Date : 2023-10-06 DOI: 10.1186/s42269-023-01120-y
Muzafar Riyaz, Savarimuthu Ignacimuthu
Abstract Background In the present era of scientific and technological advancements, the use of smartphones among people has witnessed a large-scale progression. The camera serves as an important tool on smartphones, and the quality of the built-in camera varies with megapixels. The quality of photography and videography can be enhanced by employing macro lenses that can provide precise and high-quality photographs for the documentation and monitoring of macroorganisms, particularly insects. We used a smartphone-macro lens setup (SPMLS), comprising a Redmi Note 8 Pro and Skyvik Signi-20 mm lens, along with Snapseed for image processing. The SPMLS, costing USD 217, was employed in the Hirpora Wildlife Sanctuary, Kashmir, during May to October 2021 for insect diversity documentation. The aim of this study is to introduce and demonstrate the utility of SPMLS as an affordable and portable photography solution for enhancing image quality in biodiversity documentation, making it accessible to a wide range of users. Results In this study, we report a device that uses a smartphone and macro lens (SPMLS), which is a portable and low-cost photography gear for researchers, photographers, citizen enthusiasts, and the general public who are not able to buy high-end and costly photography equipment for field-based biodiversity studies. The utilization of SPMLS has significantly augmented the image resolution and pixel density, thereby substantially enhancing the overall photographic quality, demonstrating its substantial scientific utility. Conclusions The SPMLS device presented in this study can be useful for researchers, scientists, students, citizen enthusiasts, and common people that are engaged in the biodiversity monitoring and conservation of animal and plant species across the globe. In addition, the post-photography part of this paper provides users with an outlook on image editing, processing, uploading, and marketing of photographs on different platforms.
在当今科技进步的时代,人们对智能手机的使用有了大规模的发展。摄像头是智能手机的重要工具,内置摄像头的质量因像素而异。摄影和录像的质量可以通过使用微距镜头来提高,这种镜头可以为记录和监测大型生物,特别是昆虫提供精确和高质量的照片。我们使用了智能手机微距镜头设置(SPMLS),包括一个红米Note 8 Pro和一个Skyvik Signi-20毫米镜头,以及用于图像处理的Snapseed。SPMLS耗资217美元,于2021年5月至10月在克什米尔Hirpora野生动物保护区用于昆虫多样性记录。本研究的目的是介绍和展示SPMLS作为一种可负担得起的便携式摄影解决方案的效用,以提高生物多样性文献的图像质量,使其可供广泛的用户使用。在本研究中,我们报告了一种使用智能手机和微距镜头(SPMLS)的设备,这是一种便携式和低成本的摄影设备,适用于研究人员、摄影师、公民爱好者和普通公众,他们无法购买高端和昂贵的摄影设备进行实地生物多样性研究。SPMLS的应用大大提高了图像分辨率和像素密度,从而大大提高了整体摄影质量,显示了其巨大的科学实用性。结论本研究提出的SPMLS装置可为全球从事动植物物种多样性监测和保护的科研人员、科研人员、学生、市民爱好者和普通民众提供参考。此外,本文的后期摄影部分还为用户提供了在不同平台上对照片进行编辑、处理、上传和营销的展望。
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引用次数: 0
Climate change in Kazakhstan: implications to population health 哈萨克斯坦气候变化:对人口健康的影响
Pub Date : 2023-10-06 DOI: 10.1186/s42269-023-01122-w
Toheeb Olalekan Oladejo, Fatai Omeiza Balogun, Usman Abubakar Haruna, Hassan Olayemi Alaka, Joseph Almazan, Musa Saidu Shuaibu, Ibrahim Sheu Adedayo, Zhanerke Ermakhan, Antonio Sarria-Santamerra, Don Lucero-Prisno Eliseo
Abstract Background Globally, climate change is one of the most pressing issues affecting the human race. The health of the Kazakh people is significantly impacted by climate change, which has made Kazakhstan one of the most vulnerable nations in Central Asia. This study reviews the impact of climate change on population health in Kazakhstan and provides recommendations to address these issues. Main body of the abstract This review paper evaluated available evidence and resources, which included journal articles, country reports, World Bank reports, United Nations Development Program reports, and other findings and reports relevant to the issues of climate change and the quality of life of the Kazakh people. The impact of climate change on the country is becoming more pronounced. Floods, deterioration of water quality, melting of glaciers, and extremes of temperature are some of the direct impacts of climate change observed in the country. These changes were shown to affect the health of the population. Short conclusion This review revealed mounting proof of how climate change is having an increasing impact on the lives of people in Kazakhstan. There is now an urgency to address the impact of climate change by implementing various mitigation and adaptation strategies.
在全球范围内,气候变化是影响人类最紧迫的问题之一。哈萨克斯坦人民的健康受到气候变化的严重影响,这使哈萨克斯坦成为中亚最脆弱的国家之一。本研究审查了气候变化对哈萨克斯坦人口健康的影响,并提出了解决这些问题的建议。这篇综述论文评估了现有的证据和资源,其中包括期刊文章、国别报告、世界银行报告、联合国开发计划署报告以及其他与气候变化和哈萨克斯坦人民生活质量问题相关的发现和报告。气候变化对这个国家的影响越来越明显。洪水、水质恶化、冰川融化和极端温度是该国观测到的气候变化的一些直接影响。事实证明,这些变化影响到人口的健康。这次审查揭示了越来越多的证据,表明气候变化如何对哈萨克斯坦人民的生活产生越来越大的影响。现在迫切需要通过实施各种缓解和适应战略来应对气候变化的影响。
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引用次数: 0
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Bulletin of the National Research Centre
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