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Investigation of the Effects of Autophagy Signaling on the Transcription of Yeast Retrotransposon Ty2-917 自噬信号通路对酵母反转录转座子Ty2-917转录影响的研究
Pub Date : 2021-11-22 DOI: 10.26650/eurjbiol.2021.1011143
S. Türkel, Ceyda Çolakoğlu, T. Karaduman
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引用次数: 0
Zebrafish Embryo as an Emerging Model Organism in Neurodevelopmental Toxicity Research 斑马鱼胚胎在神经发育毒性研究中的新模式生物
Pub Date : 2021-11-17 DOI: 10.26650/eurjbiol.2021.1006402
Şükriye Çalışkan, Ebru Emekli Alturfan
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引用次数: 0
Biochemical Fingerprints of Some Endemic Plants Growing in Gypsum Soils: Attenuated Total Reflection-Fourier Transform Infrared (ATR-FTIR) Spectroscopic Study 石膏土中一些特有植物的生化指纹图谱:衰减全反射-傅里叶变换红外光谱研究
Pub Date : 2021-11-17 DOI: 10.26650/eurjbiol.2021.1005264
Ayşenur Kayabaş, E. Yıldırım
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引用次数: 3
Pathogenesis of Dengue virus in Host immune system and its genomic variation 登革病毒在宿主免疫系统中的发病机制及其基因组变异
Pub Date : 2021-11-12 DOI: 10.47672/ejb.840
S. Sohail, M. Farooq, Fareeha Sohail, Hamza Rana, Husnain A. Karim, Tousif Haider, A. Shakir, M. Zafar, Samrah Saadat
Dengue viruses are the most prevalent arthropod-borne viral diseases in humans, infecting 50-100 million people each year. Its serotypes are the most common causes of arboviral illness, putting half of the world's population at risk of infection. Because there is no vaccine or antiviral medicines, the only way to manage the disease is to reduce the Aedes mosquito vectors. DENV infection can be asymptomatic or cause a self-limiting, acute febrile illness with varying degrees of severity. High fever, headache, stomach discomfort, rash, myalgia, and arthralgia are the typical symptoms of dengue fever (DF). Thrombocytopenia, vascular leakage, and hypotension are symptoms of severe dengue, dengue hemorrhagic fever (DHF), and dengue shock syndrome (DSS). Systemic shock characterizes DSS, which can be deadly. Dengue virus infection pathogenesis is linked to a complex interaction between virus, host genes, and host immune response. Major drivers of disease vulnerability include host factors such as antibody-dependent enhancement (ADE), memory cross-reactive T cells, anti-DENV NS1 antibodies, autoimmunity, and genetic variables. The NS1 protein and anti-DENV NS1 antibodies were thought to be involved in the development of severe dengue. The progressive infection may change the cytokine response of cross reactive CD4+ T cells. The need for dengue vaccines that can generate strong protective immunity against all four serotypes is required. To create such vaccines, a thorough understanding of DENV adaptive immunity is required. Structural and functional research have shown that the degree of prM protein cleavage as well as the ensemble of conformational states sampled by virions influence DENV sensitivity to antibody-mediated neutralization, which has crucial implications for vaccine formulation.
登革热病毒是人类最普遍的节肢动物传播的病毒性疾病,每年感染5000万至1亿人。其血清型是虫媒病毒性疾病的最常见原因,使世界一半人口面临感染风险。由于没有疫苗或抗病毒药物,控制这种疾病的唯一方法是减少伊蚊载体。登革热病毒感染可无症状或引起严重程度不同的自限性急性发热性疾病。高热、头痛、胃部不适、皮疹、肌痛和关节痛是登革热的典型症状。血小板减少、血管渗漏和低血压是严重登革热、登革出血热(DHF)和登革休克综合征(DSS)的症状。全身性休克是DSS的特征,可能是致命的。登革热病毒感染的发病机制与病毒、宿主基因和宿主免疫反应之间复杂的相互作用有关。疾病易感性的主要驱动因素包括宿主因素,如抗体依赖性增强(ADE)、记忆交叉反应性T细胞、抗denv NS1抗体、自身免疫和遗传变量。NS1蛋白和抗denv NS1抗体被认为与严重登革热的发展有关。进行性感染可能改变交叉反应性CD4+ T细胞的细胞因子反应。需要能够对所有四种血清型产生强大保护性免疫的登革热疫苗。要研制这种疫苗,需要对DENV适应性免疫有透彻的了解。结构和功能研究表明,prM蛋白的切割程度以及病毒粒子取样的构象状态的集合影响DENV对抗体介导的中和的敏感性,这对疫苗配方具有重要意义。
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引用次数: 0
Oxidative Stress Status in Testis of Type-2 Diabetic Rats Treated with Delta-9-Tetrahydrocannabinol δ -9-四氢大麻酚对2型糖尿病大鼠睾丸氧化应激的影响
Pub Date : 2021-11-08 DOI: 10.26650/eurjbiol.2021.1001540
Ebrar Tatar, Beti Pesen, Z. C. Coskun Yazici, S. Bolkent
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引用次数: 1
Antibiofilm and Anti-Quorum Sensing Activities of Vaginal Origin Probiotics 阴道源益生菌的抗菌膜和抗群体感应活性
Pub Date : 2021-11-05 DOI: 10.26650/eurjbiol.2021.932640
E. Kıray
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引用次数: 2
Histological and Electron Microscopical Observations on the Testis and Male Accessory Glands of Poecilimon ataturki Ünal, 1999 (Orthoptera, Tettigoniidae) 黄斑蛭睾丸及雄性副腺体的组织学和电镜观察Ünal, 1999(直翅目,蛭甲科)
Pub Date : 2021-11-01 DOI: 10.26650/eurjbiol.2021.1001795
Damla Amutkan Mutlu, I. Polat, Z. Suludere
Histological and Electron Microscopical Observations on the Testis and Male Accessory Glands of Poecilimon ataturki Ünal, 1999 (Orthoptera, Tettigoniidae). Eur
黄凤蝶睾丸和雄性副腺体的组织学和电镜观察Ünal, 1999(直翅目,蚱科)。欧元
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引用次数: 1
Evaluation of the Relationship between Epiphytic Diatoms and Water Quality Parameters in the Büyükçekmece Reservoir b<s:1> y<e:1> k<s:1> ekmece水库附生硅藻与水质参数关系的评价
Pub Date : 2021-06-11 DOI: 10.26650/EURJBIOL.2021.932485
T. Aykut, Neslihan Balkıs Özdelica, Turgay Durmuş, C. Solak
Objective: In this study carried out in Büyükçekmece Reservoir, the composition, distribution, seasonal changes of epiphytic diatoms that live on the surfaces of plants, and the effects of environmental parameters on these organisms were investigated, and it was aimed to reveal the water quality of the reservoir. Materials and Methods: In order to determine the seasonal changes of epiphytic diatom species in Büyükçekmece Reservoir, water and material samples were collected from five stations in 2019. In the study, water temperature, salinity, conductivity, dissolved oxygen, and pH values, which are among the basic ecological variables, were measured. Epiphytic diatom samples were obtained from Phragmites sp. species. Also, Spearman's rank correlation, Shannon–Weaver diversity index, Cluster (Bray–Curtis and Euclidean Distance), and ordination analysis (DCA and CCA) were applied in the study. Results: 66 epiphytic diatom species were identified in this study, and 36 of these species are new records for the reservoir. Most epiphytic diatom species were obtained in August, and the lowest number was obtained in November. According to the pH values, it was determined that the reservoir is alkaline. In addition, it was determined that the main factors affecting the distribution of epiphytic diatom species in the reservoir are temperature and conductivity, and it was revealed that ecological variables affect species distribution. Conclusion: According to conductivity and DO values, it was determined that the reservoir was of very good and of good quality, and in terms of DO values, the reservoir was mainly oligotrophic. However, station 5 was mesotrophic during the August sampling period, station 4 was mesotrophic, and station 5 was eutrophic in November. Also, Büyükçekmece Reservoir was found in poor and moderate status according to H' classification.
目的:通过对b y kekmece水库进行研究,了解植物表面附生硅藻的组成、分布、季节变化及环境参数对其的影响,以期揭示水库水质状况。材料与方法:为确定2019年b y k ekmece水库附生硅藻种类的季节变化,在5个站点采集了水和材料样品。在研究中,测量了水温、盐度、电导率、溶解氧和pH值等基本生态变量。附生硅藻样品取自芦苇属。采用Spearman等级相关、Shannon-Weaver多样性指数、聚类分析(Bray-Curtis和Euclidean Distance)和排序分析(DCA和CCA)进行研究。结果:共鉴定附生硅藻66种,其中36种为新记录种。附生硅藻种类以8月最多,11月最少。根据pH值,确定储层为碱性。此外,确定了影响水库附生硅藻种类分布的主要因素是温度和电导率,揭示了生态变量对物种分布的影响。结论:根据电导率和DO值确定储层为非常好、质量较好的储层,从DO值来看,储层以贫营养为主。8月取样期5号站为中营养型,11月4号站为中营养型,5号站为富营养型。根据H分级,发现b y k ekmece储层处于中差状态。
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引用次数: 3
Ethnobotanical study of wild flora of Haroonabad, District Bahawalnagar, Punjab, Pakistan 巴基斯坦旁遮普巴哈瓦纳加尔地区哈鲁纳巴德野生植物的民族植物学研究
Pub Date : 2020-11-23 DOI: 10.47672/ejb.564
Zobia Anwer, Siddra Shabbir, .. Qurat-ul-ain, Tanzeela Iram, Sumaira Tariq, H. Murad
Purpose: The first purpose of this study to record the new and rare use of medicinal plants in the selected area; secondly to discover the plants which were unexplored in the past and thirdly to record the Ethnobotanical data of occurring plant species.Methodology: The studied area surveyed from July to December. The plants were dried and mounted on standard herbarium sheets. The Ethnobotanical data were collected from 85 local people of Haroonabad by questionnaire.Findings: The wild flora contained 81 species within 28 families. The largest family was Poaceae with 15 species followed by Euphorbiaceae with 8 species while Asteraceae and Amaranthaceae with 7 species. The life span of plants was comprised of 47 annual species (58%) and 34 perennial species (42%). The life-form spectrum explains that Therophyte 48 species (59%) were the dominant followed by Phanerophytes 7 species (8%) and Chaemophytes 13 species (17%), Hemicryptophyte 8 species (10%), Geophytes 3 species (4%) Halophyte 1 specie (1%) and Parasite 1 specie (1%). Leaf venation classes of plants consisted of reticulate 28 species (34%), pinnate 29 species (36%), parallel 20 species (25%), palmate 2 species (2.5%) and 2 species (2.5%) were leafless thus had no leaf venation. The plant species with herbaceous stems was 68 while with woody stems 13 species. The Ethnobotanical data of 70 species were recorded because 11 plants were not known by anyone. The range of UV value was 0.09 (Chrozophora plicata Vahl.) to 0.78 (Acacia nilotica L.) and the RCF value range was 0.03 (Imperata cylindrica L.)  to 0.95 (Acacia nilotica L.). The range of ICF value was recorded from 0.45 (Hormonal disorder) to 0.78 (Respiratory disease). 57% whole plant followed by leaves (53%) was used in the ayurvedic field. Therophytes were supported in the studied region for the reason that the region is a semi-arid zone of Punjab, Pakistan.Unique contribution: The present comprehensive study provides a basic point for other researchers and enhances the knowledge of poor people related to ayurvedic field. The Ethnobotanical study tries to attract the attention towards the conservation strategies of wild plants.
目的:本研究的第一个目的是记录选定地区药用植物的新、珍稀利用情况;二是发现过去未被发现的植物,三是记录现存植物物种的民族植物学资料。方法:调查时间为7 - 12月。这些植物被晒干,装在标准的植物标本室片上。采用问卷调查的方式收集了85名哈鲁纳巴德当地居民的民族植物学资料。结果:野生植物28科81种。以豆科最多,有15种,其次是大戟科,有8种,菊科和苋科各有7种。其中一年生植物47种(58%),多年生植物34种(42%)。从生活谱上看,热生植物48种(59%)占优势,其次是显生植物7种(8%)、潜生植物13种(17%)、半隐生植物8种(10%)、地生植物3种(4%)、盐生植物1种(1%)和寄生植物1种(1%)。叶脉分类为网状28种(34%)、羽状29种(36%)、平行20种(25%)、掌状2种(2.5%)和无叶脉2种(2.5%)。草本植物68种,木本植物13种。由于有11种植物不为人所知,因此记录了70种的民族植物学资料。紫外光(UV)值为0.09 ~ 0.78,白茅(Imperata plica L.)值为0.03 ~ 0.95。ICF值从0.45(激素紊乱)到0.78(呼吸系统疾病)。在阿育吠陀领域,57%使用整株,其次是叶片(53%)。由于该地区是巴基斯坦旁遮普省的半干旱区,因此在研究区域支持热生植物。独特贡献:本综合研究为其他研究者提供了一个基本点,并提高了穷人对阿育吠陀领域的认识。民族植物学研究旨在引起人们对野生植物保护策略的关注。
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引用次数: 5
SCREENING OF COMMON BEAN GENOTYPES FOR RESISTANCE AGAINST Xanthomonas campestris pv. phaseoli IN KAKAMEGA COUNTY, KENYA 普通大豆抗油菜黄单胞菌基因型的筛选。肯尼亚卡卡梅加县的菜豆
Pub Date : 2020-11-23 DOI: 10.47672/EJB.507
Angeline Chepkemboi, J. Maingi, S. Nchore
Purpose: To screen nine available bean genotypes for resistance to common bacterial blight disease under green house and field conditions.Methodology: Experiments were conducted in randomized complete block design with three replications in a 9×2×2 factorial factor of 9 bean genotypes, grown in sterile or non-sterile soil and inoculated or non-inoculated (control) during the greenhouse and a 9×2 field screening of 9 bean genotypes, and inoculated or non-inoculated. During growth, data on plant height number of pods per plant, length of pods and size and number ofCBB spots was taken. Yield parameters were also assessed.Findings: The findings from the experiment revealed a significant variation (P<0.05) on the entire traits studied among the nine bean genotypes. Data from the field and greenhouse experiments were in conformity. None of the evaluated genotype was immune to CBB. In the green house, it was observed that disease symptoms were severe in beans planted in non-sterile soil and inoculated with Xap compared to those planted in sterile soil and non-inoculated respectively.Contribution to practice and policy: There was a strong positive correlation between size and number of CBB spots and growth and yield parameters. CAL77 and Cal 156A genotypes exhibited high levels of resistance to CBB which could improve the bean yields resulting to sufficient food supply, improved nutrition, health and improvement of the source of income to the local communities
目的:在温室和田间条件下筛选9种可用的大豆基因型对常见白叶枯病的抗性。方法:试验采用随机完全区组设计,以9×2×2因子对9个基因型、在无菌或非无菌土壤中生长、在温室期间接种或未接种(对照)的大豆进行3个重复,并对9个基因型、接种或未接种的大豆进行9×2田间筛选。生长期间,测定单株株高、荚果数、荚果长度、cbb斑点大小和数量。产量参数也进行了评估。结果:9个大豆基因型的全部性状存在显著差异(P<0.05)。田间和温室试验数据一致。所有被评估的基因型均对CBB免疫。在温室中观察到,在非无菌土壤中种植和接种了Xap的大豆,与在无菌土壤中种植和未接种Xap的大豆相比,病害症状更严重。对实践和政策的贡献:CBB斑的大小和数量与生长和产量参数之间存在很强的正相关关系。CAL77和Cal 156A基因型对CBB表现出高水平的抗性,这可以提高大豆产量,从而为当地社区提供充足的粮食供应,改善营养,健康和改善收入来源
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引用次数: 0
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Central European Journal of Biology
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