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Assessment of the accuracy of blood drawn from peripheral venous cannula used for infusing intravenous fluids/ drugs versus direct venepuncture to analyse full blood counts in febrile children. 评估用于静脉输液/药物的外周静脉插管与直接静脉穿刺的血液在分析发热儿童全血细胞计数中的准确性
IF 0.4 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-06-30 DOI: 10.4038/cmj.v66i2.9466
Ruwanthi Perera, Malithi Guruge, Amila Goonewardena, Piyumaka Peiris

Introduction: Blood sampling is a common occurrence in current paediatric practice. Dengue and other febrile illnesses are the main disease entities attributable to admissions. These admissions warrant repeated blood sampling especially with regard to full blood counts. Repeated direct pricking for sampling or having an in-situ cannula for bleeding purposes both have their own disadvantages and undesirable effects.

Objectives: Compare the accuracy of parameters of full blood count of a blood sample taken from a cannula in use against a full blood count from a direct prick.

Method: Nine parameters of the full blood count were compared in 38 paired blood samples from each subject of a cohort of febrile children aged 1-14 years admitted to Professorial Paediatric Unit of Colombo South Teaching Hospital, Kalubowila, Sri Lanka. Samples were taken when medically indicated only.

Results: The mean values of MCV and MCHC from direct venepuncture vs cannula sample were statistically different. Other parameters did not show a statistically significant difference between the samples collected by the two methods.

Conclusion: Blood sampling from a cannula in use for intravenous fluids or medications is favourable for majority of parameters of the full blood count and an advantageous alternative for fresh venepuncture bleeding in febrile children.

简介:血液采样是目前儿科实践中常见的现象。登革热和其他发热性疾病是入院的主要疾病实体。这些入院需要反复抽血,特别是全血细胞计数。反复直接穿刺取样或原位插管止血都有其缺点和不良影响。目的:比较从使用中的套管取血样本的全血细胞计数参数与直接穿刺取血样本的全血细胞计数的准确性。方法:对斯里兰卡卡卢博维拉科伦坡南教学医院儿科专业病房收治的1-14岁发热儿童的38个配对血液样本进行全血细胞计数的9个参数比较。只有在医学上有指示时才采集样本。结果:静脉直接穿刺组与静脉插管组MCV和MCHC的平均值有统计学差异。其他参数在两种方法采集的样本之间没有统计学上的显著差异。结论:在静脉输液或药物治疗中使用套管采血对全血细胞计数的大多数参数有利,对发热儿童新鲜静脉穿刺出血是一种有利的替代方法。
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引用次数: 0
Principles of natural justice, their relevance and importance to doctors. 自然正义原则及其对医生的相关性和重要性。
IF 0.4 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-06-30 DOI: 10.4038/cmj.v66i2.9464
Arosha Dissanayake, Satish Goonesinghe
Introduction In the medical curriculum, teaching of law is restricted to learning a few elementary aspects of medical jurisprudence which deal with application of scientific and medical knowledge to legal problems such as inquests. In general, medical law deals with medical negligence, consent, pregnancyrelated issues (e.g. abortion), assisted reproduction, organ donation, dying, death etc. This paper will focus on principles of natural justice, which is a key area coming under administrative law, which is distinct from medical law. Administrative law keeps the powers of the government, within their legal bounds [1]. This area of law is vital to medical practitioners in administrative inquiries in different settings. During the course of our professional lives, either as clinicians or as academics, we are called upon to hold administrative positions of varying degrees of responsibility be it as an institution head, department head, ward consultant or postgraduate trainer. These may be in different settings; Hospitals, Department of Health, Universities and the Medical Council. In the course of discharge of these duties, we invariably get involved in the conduct of hearings on disciplinary matters and other purported inappropriate conducts of those serving under our administration. The ‘errant’ medical student, the ‘difficult’ registrar or the ‘troublesome’ junior colleague in the department are experiences many of us have faced. On the other hand, we ourselves may be the subject of an inquiry. Some institutions may have procedures for inquiries laid down whilst some others may not have. Whilst complying with institutional and statutorily defined procedures, the person who holds administrative authority is expected to adhere to principles of natural justice. No institution cannot conduct an inquiry in an ad hoc or an arbitrary fashion without following these basic tenets of administrative law. Even when institutional procedures are clearly laid down, if they are at variance with tenets of administrative law and principles of natural justice, the institutional procedures will not be valid if challenged in a court of law by an aggrieved party. Ceylon Medical Journal 2021; 66: 59-62 Principles of natural justice, their relevance and importance to doctors
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引用次数: 0
Identification of bacterial aetiology in acute meningitis. 急性脑膜炎的细菌病因鉴定。
IF 0.4 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-06-30 DOI: 10.4038/cmj.v66i2.9465
Balachandran Devakanthan, Veranja Liyanapathirana, Nilanthi Dissanayake, Palitha Harasgama, Jeewaka Punchihewa

Background: The lack of rapid and sensitive test remains a key issue in diagnosing meningitis and affordability impedes using the molecular techniques. However, conventional PCR is currently becoming more affordable.

Objectives: Optimize and establish a multiplex PCR and to compare the above PCR to Cerebrospinal fluid (CSF) culture and antigen detection in sensitivity and specificity for the detection of bacterial meningitis.

Methods: CSF specimens were collected from patients with suspected acute meningitis admitted to Teaching Hospital, Peradeniya from December 2016 to March 2017. A multiplex PCR was used to detect Neisseria meningitides, Streptococcus pneumonia and Haemophilus influenzae.

Results: Eighty specimens of CSF were collected during the study period. The mean duration to sample collection was 4.78(SD 2.6) from the onset of symptoms. None of the samples given positive CSF culture. CSF antigen detection was performed on 50 specimens and all were negative. Of the total samples, eight yielded positive PCR results. In two of the positives, the full report was normal, one was suggestive of viral aetiology and five were suggestive of bacterial aetiology. Three were positive for S.pneumoniae and five for H.influenzae. positive PCR results were associated with a shorter time gap between hospitalization and sample collection and a larger CSF volume.

Conclusion: Findings of the study highlight the usefulness and recommendation of multiplex PCR in the diagnosis of pathogens causing acute bacterial meningitis. Collection of an adequate volume of CSF early in the illness, without delay may improve the diagnosis.

背景:缺乏快速、灵敏的检测方法仍然是诊断脑膜炎的一个关键问题,而可负担性阻碍了分子技术的应用。然而,传统的聚合酶链反应目前正变得越来越便宜。目的:优化建立多重PCR方法,并与脑脊液培养及抗原检测方法检测细菌性脑膜炎的敏感性和特异性进行比较。方法:收集2016年12月至2017年3月在Peradeniya教学医院收治的疑似急性脑膜炎患者的脑脊液标本。采用多重PCR检测脑膜炎奈瑟菌、肺炎链球菌和流感嗜血杆菌。结果:研究期间共采集脑脊液80份。从症状开始到样本收集的平均持续时间为4.78(SD 2.6)。所有样本脑脊液培养均未呈阳性。对50例标本进行脑脊液抗原检测,均为阴性。在全部样本中,8个获得PCR阳性结果。在两个阳性病例中,完整报告是正常的,一个提示病毒病原学,五个提示细菌病原学。其中3人肺炎链球菌阳性,5人流感嗜血杆菌阳性。阳性PCR结果与住院和采集样本之间的时间间隔较短以及脑脊液容量较大有关。结论:本研究结果强调多重PCR在急性细菌性脑膜炎病原菌诊断中的价值和推荐价值。在疾病早期及时收集足量的脑脊液可改善诊断。
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引用次数: 2
Evidence based medicine : ideology, hegemony, statistical gaze and beyond part two. 循证医学:意识形态、霸权、统计凝视及超越第二部分。
IF 0.4 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-06-30 DOI: 10.4038/cmj.v66i2.9476
Harindra Karunatilake
What gives an action its moral worth? Kant says what makes an action morally worth is not the consequence or the results that flow from that action. It has to do with the motive of the action. The motive confers the moral worth on the action. According to Kant, the only kind of motive that can confers moral worth on an action is the motive of duty and not the inclinations, one's preferences, likes, desires or impulses.
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引用次数: 0
Ссора королев. Изображения Кримгильды и Брунгильды в искусстве и литературе 皇后之争克里姆希尔德和布伦希尔德在艺术和文学中的形象
IF 0.4 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-04-05 DOI: 10.46539/CMJ.V2I1.37
Gunter E. Grimm
Главные героини германского героического эпоса «Песнь о нибелунгах» — это бургундская принцесса Кримгильда, ставшая женой главного героя Зигфрида, и исландская дева-богатырша Брунгильда, чью руку Зигфрид добывает в жестоком бою, чтобы отдать ее бургундскому королю Гунтеру в обмен на руку Кримгильды. Ревность, спор о социальном статусе, личная неприязнь между обеими героинями выливаются в жестокую ссору у ворот Вормского собора. В этой ключевой сцене одна героиня обвиняет другую в якобы имевшей место добрачной потере девственности и предъявляет сопернице пояс в качестве доказательства. Острый, напряженный конфликт характеров и воль, обрисованный в этой сцене, с давних пор интересовал деятелей искусства. Сцена «ссора королев» послужила сюжетом многочисленных художественных произведений. В настоящей статье рассматриваются особенности визуализации героинь, их тел, одежды, внешнего облика в произведениях литературы, изящного искусства и кинематографа. Статья насыщена иллюстрациями и образными примерами.
德国英雄埃波萨的主角是勃艮第公主克里姆希尔达,她是齐格弗里德的妻子,也是冰岛的富家女布伦吉尔德,齐格弗里德在一场残酷的战斗中把她的手给了勃艮第国王冈瑟,以换取克里姆希尔达的手。嫉妒,社会地位的争论,两个角色之间的个人仇恨,就像在虫堡门口的激烈争吵。在这一关键场景中,一名女主人公指责另一名女主人公婚前失身,并将腰带作为证据。在这个场景中描绘的性格和意志之间的激烈冲突长期以来一直困扰着艺术家。女王的争吵场景是许多艺术作品的情节。本文描述了角色在文学、美术和电影中的形象、身体、衣服、外形。这篇文章充满了插图和实例。
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引用次数: 0
“Playboy” как мягкая сила: влияние контента журнала на вестернизацию культуры развивающихся стран 《花花公子》就像软实力:杂志内容对发展中国家文化西方化的影响
IF 0.4 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-04-05 DOI: 10.46539/CMJ.V2I1.39
Serguey N. Yakushenkov
Журнал Playboy с самого момента его основания явился одним из ярчайших примеров культурных изменений, происходивших в США во второй половине ХХ в.. Анализируя важность журнала, автор показывает, как, казалось бы, банальная идея журнала с фотографиями обнаженных красавиц превратилась в весьма успешный коммерческий и культурный проект, оказавший огромное влияние на американское общество, да и на многие страны мира. По сути, Playboy превратился в «мягкую силу» способную генерировать новые ценности и транслировать их не только в американское общество, но и в культурный ландшафт других стран. В качестве иллюстрации этого влияния были взяты международные франшизы журнала Playboy, выходящие в других странах. Для наглядности были выбраны две версии журнала: в Бразилии и на Филиппинах. Анализ контента этих франшизных версий показывает, что в них удивительным образом сочетались традиции, заложенные основателем «Плейбоя» Хью Хефнером, и национальные стереотипы. Вместе с тем, в этом симбиозе во многом превалировали именно американские паттерны. Особенно заметно это отразилось на выборе расового типа моделей, их цвета кожи и т.д.. Кроме этого, журнал привносил в эти страны и новые системы гендерных отношений. Все это стало возможным благодаря тому, что редакция журнала создала уникальный продукт, ставший одним из неотъемлемых символов ХХ в.
《花花公子》自成立以来一直是美国20世纪下半叶文化变化最显著的例子之一。在分析该杂志的重要性时,作者展示了一本裸体美女杂志的平庸想法是如何演变成一个非常成功的商业和文化项目,对美国社会和世界上许多国家产生了巨大影响。事实上,《花花公子》已经变成了一股“软实力”,它不仅能产生新的价值,还能将其传播到美国社会,还能传播到其他国家的文化景观。为了说明这一影响,《花花公子》的国际系列被收录在其他国家。该杂志的两个版本被选中供参考:巴西和菲律宾。对这些特许经营版本内容的分析表明,《花花公子》创始人休·赫夫纳(hugh heffner)和国家刻板印象的惊人结合。然而,这种共生关系在很大程度上是由美国模式主导的。这在选择种族模型、肤色等方面尤为明显。此外,该杂志还为这些国家带来了新的性别制度。这一切都是因为杂志编辑创造了一种独特的产品,成为20世纪20年代不可或缺的象征之一。
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引用次数: 1
Телесность в стране Руставели: злоключения и путешествия грузинского тела между романтическим картвельским национализмом и потреблением массовой культуры 鲁斯塔维利国家的身体:格鲁吉亚身体在浪漫的卡特维利民族主义和大众文化消费之间的不幸和旅行
IF 0.4 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-04-05 DOI: 10.46539/CMJ.V2I1.36
Maksym W. Kyrchanoff
Автор анализирует проблемы изменений представленности тела и метаморфозы телесности в грузинской идентичности. Грузинская идентичность определяется как культурный и интеллектуальный конструкт, вдохновленный и воображенный грузинскими интеллектуалами как часть процессов социальной и политической модернизации. Анализ социальных мутаций и культурных трансформаций визуализации и актуализации грузинского национального / этнического тела и телесности в дискурсе национализма является основой целью статьи. Методологически автор использует положения и идеи, предложенные в междисциплинарных исследованиях национализма. Национальное тело определяется и анализируется как одна из изобретенных традиций грузинского национализма в контекстах модернизации и трансформации интеллектуального дискурса от модерной культуры к массовой культуре общества потребления. Предполагается, что интеллектуалы использовали телесность для актуализации этнической и культурной грузинской идентичности, подчеркивая уникальность грузинской идентичности. Анализируются проблемы сочетания и сосуществования гражданского и этнического национализма в визуализации телесности. Автор изучает, как грузинское «тело» стало политическим фактором, формой визуализации этничности и принципов политического национализма, включая концепты гражданства и лояльности, а также нации как воображаемого политического сообщества граждан с устойчивыми этническими основаниями.
作者分析了格鲁吉亚身份中身体代表性的变化和身体形态的变化问题。格鲁吉亚的身份被定义为一种文化和智力结构,受到格鲁吉亚知识分子的启发和想象,作为社会和政治现代化进程的一部分。分析民族主义话语中格鲁吉亚民族/族裔身体和身体形象化和实现的社会突变和文化转变是本文的主要目的。在方法论上,作者采用了民族主义跨学科研究中提出的观点和观点。在知识话语从现代文化到消费社会大众文化的现代化和转变的背景下,民族身体被定义和分析为格鲁吉亚民族主义发明的传统之一。据推测,知识分子利用身体来实现格鲁吉亚的民族和文化身份,强调格鲁吉亚身份的独特性。分析了公民和民族民族主义在肉身可视化中的结合与共存问题。作者研究了格鲁吉亚的“身体”是如何成为一个政治因素的,一种民族主义和政治民族主义原则的可视化形式,包括公民身份和忠诚的概念,以及一个国家是一个想象中的具有稳定种族基础的公民政治共同体。
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引用次数: 1
Визуальная конструкция смыслов – новые правила игры в погибель. Об иллюстрациях к «Песни о нибелунгах» 视觉意义结构是死亡游戏的新规则。关于“尼伯伦加之歌”的插图
IF 0.4 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-04-05 DOI: 10.46539/CMJ.V2I1.38
Sebastian Karnatz
Автор анализирует визуализацию героев немецкого героического эпоса «Песнь о нибелунгах». То, как иллюстраторы изображают тела персонажей, какие позы им придаются, на фоне какого ландшафта происходит действие, сколько действующих лиц на картине и что именно они делают – все это может стать активным семантическим фактором. Намеренное вторжение в сюжет некоторыми художниками не только создает новый контекст для восприятия, но и придает тексту иное или дополнительное значение. Иногда семантика иллюстраций находится в явном противоречии с событиями сюжета – автор показывает, как и почему это происходит, какие смыслы зашифрованы в иллюстрациях к поэме, как изображения влияют на восприятие текста реципиентами.
作者分析了德国英雄史诗《尼伯伦之歌》中人物的形象化。插画家如何描绘人物的身体,给他们什么姿势,在什么景观的背景下发生的动作,图片中有多少角色,他们做了什么-所有这些都可以成为一个积极的语义因素。一些艺术家故意侵入主题不仅创造了一个新的感知背景,而且赋予了文本不同或额外的含义。有时,插图的语义与情节事件明显矛盾——作者展示了如何以及为什么发生,诗歌插图中编码的含义,图像如何影响接收者对文本的感知。
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引用次数: 0
Impact of COVID-19 on the mental health of frontline and non-frontline healthcare workers in Sri Lanka. 2019冠状病毒病对斯里兰卡一线和非一线医护人员心理健康的影响
IF 0.4 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-03-31 DOI: 10.4038/cmj.v66i1.9351
Anuradha Baminiwatta, Shamila De Silva, Aruni Hapangama, Kumarini Basnayake, Charani Abayaweera, Dinithi Kulasinghe, Dewmi Kaushalya, Shehan Williams
IntroductionHealthcare workers (HCWs) are at risk of mental health problems during a pandemic. Being stationed at the frontline or not may have implications on their mental health.ObjectivesThe aims of this study were to assess depression, anxiety and stress among HCWs, to explore differences between frontline and non-frontline workers, and to investigate associated factors.MethodsIn this cross-sectional study, frontline and non-frontline HCWs were recruited from a COVID-19 screening hospital in Sri Lanka. Mental health impact was assessed using Depression, Anxiety and Stress Scale (DASS-21). Sociodemographic data and perceptions of social and occupational circumstances were gathered. Categorical variables were analyzed using Chi square and logistic regression. Odds ratios were calculated for the effect of different perceptions on psychological morbidity.ResultsA total of 467 HCWs participated, comprising 244 (52.2%) frontline and 223 (47.8%) non-frontline workers, with female preponderance (n=341, 77%). Prevalence of depression, anxiety and stress among HCWs were 19.5%, 20.6%, 11.8%, respectively. Non-frontline group showed a higher prevalence of depression (27% vs. 11%, p<0.001), anxiety (27% vs. 14%, p=0.001) and stress (15% vs. 8%, p=0.026). Being married, having children, living with family and higher income were associated with better psychological outcomes. Perceived lack of personal protective equipment, inadequate support from hospital authorities, greater discrimination, and lack of training to cope with the situation predicted poor mental health outcomes, and non-frontline HCWs were more likely to hold such perceptions.ConclusionAddressing factors leading to negative psychological outcomes in HCWs should be a key concern during this pandemic.
在大流行期间,卫生保健工作者(HCWs)面临精神健康问题的风险。是否驻扎在前线可能对他们的心理健康产生影响。目的:本研究旨在评估医护人员的抑郁、焦虑和压力,探讨一线与非一线医护人员的差异,并探讨相关因素。方法:在横断面研究中,从斯里兰卡一家COVID-19筛查医院招募一线和非一线医护人员。采用抑郁、焦虑和压力量表(DASS-21)评估心理健康影响。收集了社会人口统计数据和对社会和职业环境的看法。分类变量分析采用卡方和逻辑回归。计算了不同认知对心理疾病的影响的比值比。结果:共有467名医护人员参与调查,其中一线244人(52.2%),非一线223人(47.8%),女性占多数(n=341, 77%)。健康护理人员的抑郁、焦虑和压力患病率分别为19.5%、20.6%和11.8%。非一线组显示出更高的抑郁症患病率(27%对11%)。结论:在这次大流行期间,解决导致卫生保健工作者负面心理结果的因素应该是一个关键问题。
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引用次数: 5
Parametrial tumour causing hydronephrosis and hydroureter due to IgG4 mediated retroperitoneal fibrosis; A laparoscopic resection. IgG4介导的腹膜后纤维化引起的伴侧肿瘤肾积水和输尿管积水;腹腔镜切除术。
IF 0.4 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-03-31 DOI: 10.4038/cmj.v66i1.9360
Dhammike Silva, Prabath Randombage, Wedisha Gankanda, Rukshani Edirisinghe, Janani Mathanamohan, Chandu De Silva
Retroperitoneal fibrosis (RPF) is a disease that develops following inflammation and fibrosis of the retroperitoneum and other abdominal organs, which manifests with various local and systemic symptoms. It has several entities, namely the idiopathic RPF (IRPF), secondary RPF and Immunoglobulin G4-related disease (IgG4-RD). The role of a gynaecologist in the management of retroperitoneal fibrosis is highlighted in this case of a parametrial tumour causing retroperitoneal fibrosis and hence leading to hydronephrosis and hydroureter as a consequence. A 49-year-old woman presenting with a symptom cluster suggestive of acute pyelonephritis was found to have reduced eGFR. Elevated levels of inflammatory markers indicated an inflammatory nature of the disease, in addition to a normochromic anaemia that could be due to chronic inflammation itself. CECT Neck, Chest, Abdomen and Pelvis revealed mild hydronephrosis with a distal narrowing and a retroperitoneal confluent mass. Investigations led to suspect an invasive left ovarian malignancy or an endometriotic nodule with ureteric compression, which was later thought to be unlikely with a normal CA-125 level. To obtain a better understanding, a cysto-ureteroscopy was performed where she was found to have an obstruction. Although stent placement is a reasonable temporary mode of symptom relief, this was proven unsuccessful. Surgical management was opted for considering the severity of her symptoms and the course of time it would take for medical management to take effect. In addition, laparoscopy would aid in the exclusion of other pelvic pathologies under direct vision and treat any if found concurrently. Consequently, a laparoscopic hysterectomy, bilateral salpingo-oophorectomy, left sided ureterolysis with careful resection of the densely adhered tumour surrounding the left cysto-ureteric junction was performed, followed by retrograde ureteric stenting. Histology revealed retro-peritoneal fibrosis, and further immunohistochemistry pointed towards a diagnosis of IgG4 related sclerosing disease. This was also supported by elevated levels of IgG, especially the IgG4 component. Disseminated RPF was subsequently excluded by CECT. Following surgery, she was started on high dose corticosteroids and the stent was left in place for six weeks. She is being kept on a maintenance dose of low dose corticosteroids without disease relapse. Regular follow-up with inflammatory markers, serum IgG4 levels and imaging demonstrate adequate response to corticosteroid therapy.
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Ceylon Medical Journal
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