Pub Date : 2025-12-09DOI: 10.1016/j.chest.2025.07.4072
Ryosuke Imai, Rene S. Bermea, Sophia H. Zhao, Barry S. Shea, Robert W. Hallowell
{"title":"Response","authors":"Ryosuke Imai, Rene S. Bermea, Sophia H. Zhao, Barry S. Shea, Robert W. Hallowell","doi":"10.1016/j.chest.2025.07.4072","DOIUrl":"https://doi.org/10.1016/j.chest.2025.07.4072","url":null,"abstract":"","PeriodicalId":9782,"journal":{"name":"Chest","volume":"3 1","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145730722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-09DOI: 10.1016/j.chest.2025.06.032
Daniel Whitt, William “Claibe” Yarbrough
{"title":"The Veterans Health Administration Vision of Advanced Practice Respiratory Therapists","authors":"Daniel Whitt, William “Claibe” Yarbrough","doi":"10.1016/j.chest.2025.06.032","DOIUrl":"https://doi.org/10.1016/j.chest.2025.06.032","url":null,"abstract":"","PeriodicalId":9782,"journal":{"name":"Chest","volume":"422 1","pages":"1295-1297"},"PeriodicalIF":9.6,"publicationDate":"2025-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145732202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-09DOI: 10.1016/j.chest.2025.11.037
Kristen R Mathias,Ali M Mustafa,Kayla J Nyakinye,Victoria Wotoroson,Barney J Stern,Carlos A Pardo,Edward S Chen,Nancy W Lin,Stephen C Mathai,Nisha A Gilotra,Michelle Sharp
Sarcoidosis is a systemic disease characterized by marked clinical equipoise regarding optimal methods for disease diagnosis, monitoring, and treatment. As a result of these challenges, patients with sarcoidosis face substantial delays in care and have reported psychological distress from the uncertainty they face throughout their care journeys. In complex diseases with multisystemic involvement, multidisciplinary care models can help provide diagnostic clarity and streamline care. Although experts and guidelines in the field advocate for multidisciplinary care to improve clinical management of sarcoidosis, there is limited primary literature describing implementation of these care models in sarcoidosis. In this review, we outline best practices and common challenges associated with establishing a multidisciplinary care team for sarcoidosis. We describe the development of the Johns Hopkins Sarcoidosis Center (JHSC) multidisciplinary team as well as the formation of the Johns Hopkins Sarcoidosis patient advisory board, which helps inform the team's goals and initiatives. Finally, we review the broader literature on multidisciplinary care models in sarcoidosis and interstitial lung disease, identifying areas for further study.
{"title":"TEAM Sarcoidosis: Creating a Multidisciplinary Care Team for Complex Clinical Management.","authors":"Kristen R Mathias,Ali M Mustafa,Kayla J Nyakinye,Victoria Wotoroson,Barney J Stern,Carlos A Pardo,Edward S Chen,Nancy W Lin,Stephen C Mathai,Nisha A Gilotra,Michelle Sharp","doi":"10.1016/j.chest.2025.11.037","DOIUrl":"https://doi.org/10.1016/j.chest.2025.11.037","url":null,"abstract":"Sarcoidosis is a systemic disease characterized by marked clinical equipoise regarding optimal methods for disease diagnosis, monitoring, and treatment. As a result of these challenges, patients with sarcoidosis face substantial delays in care and have reported psychological distress from the uncertainty they face throughout their care journeys. In complex diseases with multisystemic involvement, multidisciplinary care models can help provide diagnostic clarity and streamline care. Although experts and guidelines in the field advocate for multidisciplinary care to improve clinical management of sarcoidosis, there is limited primary literature describing implementation of these care models in sarcoidosis. In this review, we outline best practices and common challenges associated with establishing a multidisciplinary care team for sarcoidosis. We describe the development of the Johns Hopkins Sarcoidosis Center (JHSC) multidisciplinary team as well as the formation of the Johns Hopkins Sarcoidosis patient advisory board, which helps inform the team's goals and initiatives. Finally, we review the broader literature on multidisciplinary care models in sarcoidosis and interstitial lung disease, identifying areas for further study.","PeriodicalId":9782,"journal":{"name":"Chest","volume":"31 4 1","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145728579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-09DOI: 10.1016/j.chest.2025.10.020
George M. Solomon, Nathan C. Dean
{"title":"Endotypes in Bronchiectasis","authors":"George M. Solomon, Nathan C. Dean","doi":"10.1016/j.chest.2025.10.020","DOIUrl":"https://doi.org/10.1016/j.chest.2025.10.020","url":null,"abstract":"","PeriodicalId":9782,"journal":{"name":"Chest","volume":"227 1","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145730724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-08DOI: 10.1016/j.chest.2025.11.035
Sarah L. Khan MD, Carly J. Paoli PharmD, Noah Kime BS, Kayleen Williams MPH, Gabriela Gomez Rendon MD, Adriano R. Tonelli MD, Hector Cajigas MD, Stephen C. Mathai MD, Sandeep Sahay MD
Current evidence supports risk-based treatment for pulmonary arterial hypertension (PAH) with an endothelin receptor antagonist and phosphodiesterase type 5 inhibitor as initial therapy for patients with low- and intermediate-risk PAH, and triple therapy with the addition of a parenteral prostacyclin for patients with high-risk PAH.
{"title":"Treatment patterns in incident pulmonary hypertension patients: real-world data from the Pulmonary Hypertension Association Registry","authors":"Sarah L. Khan MD, Carly J. Paoli PharmD, Noah Kime BS, Kayleen Williams MPH, Gabriela Gomez Rendon MD, Adriano R. Tonelli MD, Hector Cajigas MD, Stephen C. Mathai MD, Sandeep Sahay MD","doi":"10.1016/j.chest.2025.11.035","DOIUrl":"https://doi.org/10.1016/j.chest.2025.11.035","url":null,"abstract":"Current evidence supports risk-based treatment for pulmonary arterial hypertension (PAH) with an endothelin receptor antagonist and phosphodiesterase type 5 inhibitor as initial therapy for patients with low- and intermediate-risk PAH, and triple therapy with the addition of a parenteral prostacyclin for patients with high-risk PAH.","PeriodicalId":9782,"journal":{"name":"Chest","volume":"7 1","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145697339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-08DOI: 10.1016/j.chest.2025.11.034
Pei Ye Li MD MEng, Andrea Gershon MD MSc, Andrew Kouri MD PhD
Large Language Models (LLMs) are demonstrating increasing promise across clinical applications, but their domain specific knowledge in asthma has not been thoroughly explored. Additionally, state-of-the-art models released in 2025 (ChatGPT-5, ChatGPT-o3, Claude-3.7, DeepSeek-V3, Grok-3) have yet to be studied in asthma.
{"title":"Evaluating the Accuracy of Large Language Models in Answering Asthma Multiple Choice and Objective Structured Clinical Examination Questions","authors":"Pei Ye Li MD MEng, Andrea Gershon MD MSc, Andrew Kouri MD PhD","doi":"10.1016/j.chest.2025.11.034","DOIUrl":"https://doi.org/10.1016/j.chest.2025.11.034","url":null,"abstract":"Large Language Models (LLMs) are demonstrating increasing promise across clinical applications, but their domain specific knowledge in asthma has not been thoroughly explored. Additionally, state-of-the-art models released in 2025 (ChatGPT-5, ChatGPT-o3, Claude-3.7, DeepSeek-V3, Grok-3) have yet to be studied in asthma.","PeriodicalId":9782,"journal":{"name":"Chest","volume":"30 1","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145697347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-08DOI: 10.1016/j.chest.2025.11.036
Elochukwu Ezenwankwo,Nicholas Yell,Jan M Eberth
{"title":"Lung Cancer Screening in the United States, 2024: A National Health Interview Survey Analysis.","authors":"Elochukwu Ezenwankwo,Nicholas Yell,Jan M Eberth","doi":"10.1016/j.chest.2025.11.036","DOIUrl":"https://doi.org/10.1016/j.chest.2025.11.036","url":null,"abstract":"","PeriodicalId":9782,"journal":{"name":"Chest","volume":"169 1","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145717632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-06DOI: 10.1016/j.chest.2025.11.031
Sohee Park, Min-Ju Kim, Jang Ho Lee, Hye Jeon Hwang, Sang Min Lee, Eun Jin Chae, Joon Beom Seo, Ho Cheol Kim, Jooae Choe
{"title":"Quantitative CT in Progressive Pulmonary Fibrosis: Clinical Utility and Meaningful Threshold Definition","authors":"Sohee Park, Min-Ju Kim, Jang Ho Lee, Hye Jeon Hwang, Sang Min Lee, Eun Jin Chae, Joon Beom Seo, Ho Cheol Kim, Jooae Choe","doi":"10.1016/j.chest.2025.11.031","DOIUrl":"https://doi.org/10.1016/j.chest.2025.11.031","url":null,"abstract":"","PeriodicalId":9782,"journal":{"name":"Chest","volume":"1 1","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145689549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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