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A 36-Year-Old Man With Hemoptysis and Fevers 36岁男性，咯血发热
IF 9.6 1区 医学 Q1 CRITICAL CARE MEDICINE
Chest
Pub Date : 2026-02-09 DOI: 10.1016/j.chest.2025.09.016
Stephen Mitchell, Olga Gomez Rojas, Akshay Mathavan, Akash Mathavan, Ali Ataya
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引用次数: 0
Conformal Prediction in Clinical Artificial Intelligence 临床人工智能的适形预测
IF 9.6 1区 医学 Q1 CRITICAL CARE MEDICINE
Chest
Pub Date : 2026-02-09 DOI: 10.1016/j.chest.2025.07.4116
Xiaofeng Wang, Samer Albahra, Faming Liang, Abhijit Duggal, Raed A. Dweik
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引用次数: 0
Beyond the Borg Scale 超越博格规模
IF 9.6 1区 医学 Q1 CRITICAL CARE MEDICINE
Chest
Pub Date : 2026-02-09 DOI: 10.1016/j.chest.2025.09.010
Bryce N. Balmain, Vipa Bernhardt
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引用次数: 0
Right Atrial Mass in a 63-Year-Old Woman 63岁女性右心房肿块
IF 9.6 1区 医学 Q1 CRITICAL CARE MEDICINE
Chest
Pub Date : 2026-02-09 DOI: 10.1016/j.chest.2025.09.008
Kyle Admire, Li Li, Xian Qiao
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引用次数: 0
A 62-Year-Old-Man With Severe Daytime Sleepiness After Primary Central Nervous System Lymphoma 62岁男性原发性中枢神经系统淋巴瘤后出现严重日间嗜睡
IF 9.6 1区 医学 Q1 CRITICAL CARE MEDICINE
Chest
Pub Date : 2026-02-09 DOI: 10.1016/j.chest.2025.08.017
Jindapa Srikajon, Athiwat Tripipitsiriwat, Jeremy E. Orr
{"title":"A 62-Year-Old-Man With Severe Daytime Sleepiness After Primary Central Nervous System Lymphoma","authors":"Jindapa Srikajon, Athiwat Tripipitsiriwat, Jeremy E. Orr","doi":"10.1016/j.chest.2025.08.017","DOIUrl":"https://doi.org/10.1016/j.chest.2025.08.017","url":null,"abstract":"","PeriodicalId":9782,"journal":{"name":"Chest","volume":"119 1","pages":""},"PeriodicalIF":9.6,"publicationDate":"2026-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146153300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Daily Physical Activity in Pulmonary Arterial Hypertension: Insights from a Multicenter Longitudinal Trial Using Accelerometry 肺动脉高压的日常体育活动：来自多中心纵向试验的见解
IF 9.6 1区 医学 Q1 CRITICAL CARE MEDICINE
Chest
Pub Date : 2026-02-04 DOI: 10.1016/j.chest.2025.12.052
Jasleen Minhas, Haochang Shou, Nadine Al-Naamani, Rui Feng, Roham Zamanian, Todd Bull, Murali Chakinala, Anna Hemnes, Jude Moutchia, Stephen C. Mathai, Susan Ellenberg, Corey Ventetuolo, Steven M. Kawut
{"title":"Daily Physical Activity in Pulmonary Arterial Hypertension: Insights from a Multicenter Longitudinal Trial Using Accelerometry","authors":"Jasleen Minhas, Haochang Shou, Nadine Al-Naamani, Rui Feng, Roham Zamanian, Todd Bull, Murali Chakinala, Anna Hemnes, Jude Moutchia, Stephen C. Mathai, Susan Ellenberg, Corey Ventetuolo, Steven M. Kawut","doi":"10.1016/j.chest.2025.12.052","DOIUrl":"https://doi.org/10.1016/j.chest.2025.12.052","url":null,"abstract":"","PeriodicalId":9782,"journal":{"name":"Chest","volume":"399 1","pages":""},"PeriodicalIF":9.6,"publicationDate":"2026-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146109977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcomes of severe mpox admitted to intensive care units at two large New York City health systems, 2022-2024 2022-2024年，纽约市两大卫生系统重症监护病房收治的严重mpox的结果
IF 9.6 1区 医学 Q1 CRITICAL CARE MEDICINE
Chest
Pub Date : 2026-02-03 DOI: 10.1016/j.chest.2026.01.016
Anthony J. Lo Piccolo:, Shane Antoinette Arante, Justin Chan, Kathryn Jano, Madeline A. DiLorenzo, Melissa Achenbaum, Regan Britt, David Butler, Radu Postelnicu, Erin McGuire, Vikramjit Mukherjee
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引用次数: 0
Judgment Under Uncertainty: A Case-based Analysis of Cognitive Bias in ECMO Candidacy Decision-Making 不确定性下的判断：基于案例的ECMO候选决策认知偏差分析
IF 9.6 1区 医学 Q1 CRITICAL CARE MEDICINE
Chest
Pub Date : 2026-02-03 DOI: 10.1016/j.chest.2026.01.014
Alexander E. Jacobs, Derek R. Soled, Jonah Rubin
{"title":"Judgment Under Uncertainty: A Case-based Analysis of Cognitive Bias in ECMO Candidacy Decision-Making","authors":"Alexander E. Jacobs, Derek R. Soled, Jonah Rubin","doi":"10.1016/j.chest.2026.01.014","DOIUrl":"https://doi.org/10.1016/j.chest.2026.01.014","url":null,"abstract":"","PeriodicalId":9782,"journal":{"name":"Chest","volume":"103 1","pages":""},"PeriodicalIF":9.6,"publicationDate":"2026-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146109984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Procedure Patterns and Survival in Advanced Non-Small Cell Lung Cancer With Malignant Airway Obstruction: A Surveillance, Epidemiology, and End Results Medicare Analysis. 手术模式和晚期非小细胞肺癌伴恶性气道阻塞的生存率：一项SEER-Medicare分析。
IF 8.6 1区 医学 Q1 CRITICAL CARE MEDICINE
Chest
Pub Date : 2026-02-01 Epub Date: 2025-08-27 DOI: 10.1016/j.chest.2025.07.4088
Septimiu D Murgu, Meijia Zhou, Balaji Laxmanan, Charlene A Wong, Tony B Amos, Iftekhar Kalsekar, Anil Vachani

Background: Malignant airway obstruction (MAO) is a common, debilitating complication in advanced lung cancer. Therapeutic bronchoscopy is successfully applied to manage MAO. MAO recurs and requires repeat procedures.

Research question: What are the patterns of repeat therapeutic bronchoscopy, associated factors of repeat procedures, and overall survival (OS) in advanced non-small cell lung cancer (NSCLC) and concurrent MAO?

Study design and methods: This retrospective cohort analysis used the Surveillance, Epidemiology, and End Results (SEER)-Medicare-linked database for patients newly diagnosed with advanced-stage NSCLC (ie, stage III/IV) from 2006 to 2019. Patients aged ≥ 66 years with NSCLC who underwent therapeutic bronchoscopy for MAO within 6 months of diagnosis were identified using procedure codes. The index procedure was categorized as endoluminal therapy, airway stent, airway stent with endoluminal therapy, or photodynamic therapy. Postindex repeat procedure patterns, including incidence, time to first repeat procedure, and unadjusted repeat procedure trends, were examined. OS was assessed by using the Kaplan-Meier method from the date of index therapeutic bronchoscopy over 6 months, 1 year, and 2 years.

Results: A total of 1,092 patients (excluding 24 who received index photodynamic therapy) with advanced-stage NSCLC (48.9% stage III, 51.1% stage IV) and concurrent MAO were included. Endoluminal therapy was the common index bronchoscopy intervention (71.8%). Overall, the proportion of repeat procedure within 1 year was 25.4%. For those who underwent first repeat procedures, 74.4% had the procedure within 30 days. Endoluminal therapy was frequently used as the repeat procedure modality (85.8%). Repeat procedures decreased from 31.1% in 2006 to 19.8% in 2017. Overall, 6-month, 1-year, and 2-year OS were 44.9%, 29.8%, and 17.1%, with a median OS of 4.5 months.

Interpretation: This analysis showed that one-fourth of NSCLC patients with MAO underwent repeat therapeutic bronchoscopy, most occurring within 30 days following the initial procedure. Survival outcomes require further exploration to optimize therapeutic opportunities in this population.

背景：恶性气道阻塞（MAO）是晚期肺癌中一种常见的衰弱性并发症。治疗性支气管镜成功应用于MAO的治疗。MAO复发，需要重复的程序。研究问题：晚期非小细胞肺癌（NSCLC）并发MAO的重复支气管镜治疗模式、重复手术的相关因素和总生存期（OS）是什么？研究设计和方法：本回顾性队列分析利用监测、流行病学和最终结果(SEER)-医疗保险关联数据库，对2006年至2019年新诊断为晚期III/IV期NSCLC的患者进行分析。年龄≥66岁的NSCLC患者在诊断后6个月内接受治疗性支气管镜检查诊断MAO，使用程序代码进行鉴定。指标程序分为腔内治疗、气道支架、气道支架联合腔内治疗或光动力治疗（PDT）。我们检查了索引后重复手术模式，包括发生率、第一次重复手术的时间和未调整的重复手术趋势。使用Kaplan-Meier法从支气管镜检查指标开始，在6个月、1年和2年内评估OS。结果：1092例晚期NSCLC患者（不包括24例接受指数PDT的患者）（48.9%为III期，51.1%为IV期）并发MAO。腔内治疗是支气管镜干预的常见指标（71.8%）。总体而言，一年内重复手术的比例为25.4%。在首次接受重复手术的患者中，74.4%的患者在30天内完成了手术。重复手术方式多采用腔内治疗（85.8%）。重复手术从2006年的31.1%下降到2017年的19.8%。总体而言，6个月、1年和2年的生存期分别为44.9%、29.8%和17.1%，中位生存期为4.5个月。解释：四分之一的非小细胞肺癌MAO患者接受了重复治疗性支气管镜检查，大多数发生在初始手术后30天内。生存结果需要进一步探索，以优化该人群的治疗机会。
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引用次数: 0
Sex does not modify prediction of asthma attacks by clinical risk factors and Type-2 biomarkers 性别不能改变临床危险因素和2型生物标志物对哮喘发作的预测
IF 9.6 1区 医学 Q1 CRITICAL CARE MEDICINE
Chest
Pub Date : 2026-01-31 DOI: 10.1016/j.chest.2025.12.049
Sebastian Riemann, Fleur L. Meulmeester, Samuel Mailhot-Larouche, Sanjay Ramakrishnan, Michael E. Wechsler, Jonathan Corren, Sarah E. Diver, Christopher E. Brightling, Mario Castro, Nicola A. Hanania, David J. Jackson, Neil Martin, Annette Laugerud, Deborah Clarke, Alison Moore, Megan E. Hardin, Cecile T.J. Holweg, Subhashini Allu, Timothy S.C. Hinks, Richard W. Beasley, Jacob K. Sont, Ewout W. Steyerberg, Ian D. Pavord, Guy Brusselle, Simon Couillard
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引用次数: 0
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