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Beyond Palliative Care: Exploring Hospital-Level Drivers of Persistent Critical Illness. 超越姑息治疗：探索医院层面的持续危重疾病驱动因素。
IF 9.6 1区 医学 Q1 CRITICAL CARE MEDICINE
Chest
Pub Date : 2026-01-01 DOI: 10.1016/j.chest.2025.08.046
Wangfei Ji,Zhen Zhou
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引用次数: 0
"Policy or Perception?": Rethinking the Influence of Hospital Guidelines on ICU Decisions. “政策还是观念？”重新思考医院指南对ICU决策的影响。
IF 9.6 1区 医学 Q1 CRITICAL CARE MEDICINE
Chest
Pub Date : 2026-01-01 DOI: 10.1016/j.chest.2025.07.4109
Zhihao Lei
{"title":"\"Policy or Perception?\": Rethinking the Influence of Hospital Guidelines on ICU Decisions.","authors":"Zhihao Lei","doi":"10.1016/j.chest.2025.07.4109","DOIUrl":"https://doi.org/10.1016/j.chest.2025.07.4109","url":null,"abstract":"","PeriodicalId":9782,"journal":{"name":"Chest","volume":"17 1","pages":"e35-e36"},"PeriodicalIF":9.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145947472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Concerns Regarding Sample Size Calculation, Power, and Reference Event Rate in the DecatSepsis Trial. DecatSepsis试验中样本量计算、功率和参考事件发生率的关注。
IF 9.6 1区 医学 Q1 CRITICAL CARE MEDICINE
Chest
Pub Date : 2026-01-01 DOI: 10.1016/j.chest.2025.08.035
Venkata Ganesh,Kaminder Bir Kaur,Vikas Saini
{"title":"Concerns Regarding Sample Size Calculation, Power, and Reference Event Rate in the DecatSepsis Trial.","authors":"Venkata Ganesh,Kaminder Bir Kaur,Vikas Saini","doi":"10.1016/j.chest.2025.08.035","DOIUrl":"https://doi.org/10.1016/j.chest.2025.08.035","url":null,"abstract":"","PeriodicalId":9782,"journal":{"name":"Chest","volume":"3 1","pages":"e33-e34"},"PeriodicalIF":9.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145947474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of Shared Decision-Making With Long-Term Adherence to Lung Cancer Screening: If a Decision Is Shared, Does It Last Longer? For Lung Cancer Screening, Maybe Yes. 共同决策与长期坚持肺癌筛查的关系：如果共同决策，它会持续更长时间吗？对于肺癌筛查，可能是。
IF 9.6 1区 医学 Q1 CRITICAL CARE MEDICINE
Chest
Pub Date : 2026-01-01 DOI: 10.1016/j.chest.2025.07.4127
Brett C Bade,Jamie L Studts
{"title":"Association of Shared Decision-Making With Long-Term Adherence to Lung Cancer Screening: If a Decision Is Shared, Does It Last Longer? For Lung Cancer Screening, Maybe Yes.","authors":"Brett C Bade,Jamie L Studts","doi":"10.1016/j.chest.2025.07.4127","DOIUrl":"https://doi.org/10.1016/j.chest.2025.07.4127","url":null,"abstract":"","PeriodicalId":9782,"journal":{"name":"Chest","volume":"5 1","pages":"22-23"},"PeriodicalIF":9.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145947482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Failure to Report Sex-Specific Risk Factors in Heart Failure With Preserved Ejection Fraction Research: A Scoping Review. 在保留射血分数的心力衰竭研究中，没有报告性别特异性的危险因素：一项范围审查。
IF 8.6 1区 医学 Q1 CRITICAL CARE MEDICINE
Chest
Pub Date : 2026-01-01 Epub Date: 2025-08-26 DOI: 10.1016/j.chest.2025.07.4082
Kathryn A Drury, Josie A Seeto, Serena Hong, Michael A Wewege, Amanda D Hagstrom

Background: Despite research identifying clear sex-specific differences in the risk profile for heart failure with preserved ejection fraction (HFpEF), these risk factors are typically not reported in "participant characteristics" of heart failure research. This leads to an incomplete understanding of how and why female individuals are heavily predisposed to developing HFpEF.

Research question: To what extent do current HFpEF studies report sex-specific risk factors in their participant descriptions?

Study design and methods: A scoping review was conducted in accordance with PRISMA-Scoping Review guidelines. Data extracted included proportion of female and male participants, reporting of sex-neutral risk factors, and reporting of sex-specific risk factors.

Results: None of the 68 randomized controlled trials (RCTs) reported sex-specific risk factors in their participant descriptions. Only 24 of 68 studies mentioned sex disaggregation in their results or statistical models.

Interpretation: Including sex-specific risk factors of participants is essential for advancing our understanding of disease causes, improving treatment strategies, enhancing risk prediction models, and promoting equitable health care for both male and female individuals. Including sex-specific risk factors contributes to more informed decision-making in both research and clinical practice.

背景：尽管研究确定了保留射血分数（HFpEF）心力衰竭的风险特征存在明显的性别差异，但这些风险因素通常未在心力衰竭研究的“参与者特征”中报道。这导致了对女性如何以及为什么容易患上HFpEF的不完全理解。研究问题：目前的HFpEF研究在多大程度上在参与者描述中报告了性别特异性风险因素？研究设计和方法：根据PRISMA-ScR指南进行范围审查。提取的数据包括女性和男性参与者的比例，报告性别中性风险因素和报告性别特异性风险因素。结果：68项随机对照试验均未在参与者描述中报告性别特异性风险因素。只有24/68项研究在其结果或统计模型中提到了性别分解。解释：包括参与者的性别特异性风险因素对于提高我们对疾病病因的理解，改进治疗策略，增强风险预测模型，促进男女平等的医疗保健至关重要。包括性别特异性风险因素有助于在研究和临床实践中做出更明智的决策。
{"title":"Failure to Report Sex-Specific Risk Factors in Heart Failure With Preserved Ejection Fraction Research: A Scoping Review.","authors":"Kathryn A Drury, Josie A Seeto, Serena Hong, Michael A Wewege, Amanda D Hagstrom","doi":"10.1016/j.chest.2025.07.4082","DOIUrl":"10.1016/j.chest.2025.07.4082","url":null,"abstract":"<p><strong>Background: </strong>Despite research identifying clear sex-specific differences in the risk profile for heart failure with preserved ejection fraction (HFpEF), these risk factors are typically not reported in \"participant characteristics\" of heart failure research. This leads to an incomplete understanding of how and why female individuals are heavily predisposed to developing HFpEF.</p><p><strong>Research question: </strong>To what extent do current HFpEF studies report sex-specific risk factors in their participant descriptions?</p><p><strong>Study design and methods: </strong>A scoping review was conducted in accordance with PRISMA-Scoping Review guidelines. Data extracted included proportion of female and male participants, reporting of sex-neutral risk factors, and reporting of sex-specific risk factors.</p><p><strong>Results: </strong>None of the 68 randomized controlled trials (RCTs) reported sex-specific risk factors in their participant descriptions. Only 24 of 68 studies mentioned sex disaggregation in their results or statistical models.</p><p><strong>Interpretation: </strong>Including sex-specific risk factors of participants is essential for advancing our understanding of disease causes, improving treatment strategies, enhancing risk prediction models, and promoting equitable health care for both male and female individuals. Including sex-specific risk factors contributes to more informed decision-making in both research and clinical practice.</p>","PeriodicalId":9782,"journal":{"name":"Chest","volume":" ","pages":"174-178"},"PeriodicalIF":8.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144944554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiographic Phenotypes Should Inform Surgical Decision-Making in 2 to 3 cm Non-Small-Cell Lung Cancer. 2 ~ 3cm非小细胞肺癌的影像学表型应作为手术决策的依据。
IF 9.6 1区 医学 Q1 CRITICAL CARE MEDICINE
Chest
Pub Date : 2026-01-01 DOI: 10.1016/j.chest.2025.08.051
Guangdong Wang,Tingting Liu,Wenwen Ji,Zhihong Shi
{"title":"Radiographic Phenotypes Should Inform Surgical Decision-Making in 2 to 3 cm Non-Small-Cell Lung Cancer.","authors":"Guangdong Wang,Tingting Liu,Wenwen Ji,Zhihong Shi","doi":"10.1016/j.chest.2025.08.051","DOIUrl":"https://doi.org/10.1016/j.chest.2025.08.051","url":null,"abstract":"","PeriodicalId":9782,"journal":{"name":"Chest","volume":"15 1","pages":"e42-e43"},"PeriodicalIF":9.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145947466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A 45-Year-Old Woman With Hereditary Hemorrhagic Telangiectasia and Persistent Exertional Dyspnea and Peripheral Edema. 45岁女性，遗传性出血性毛细血管扩张，持续性用力呼吸困难和周围水肿。
IF 9.6 1区 医学 Q1 CRITICAL CARE MEDICINE
Chest
Pub Date : 2026-01-01 DOI: 10.1016/j.chest.2025.08.004
Helen Triantafyllidi,Dionysia Birmpa,Anastasia Fambri,Dimitrios Benas,David Montani
We report the case of a 45-year-old woman who was referred to our Cardiology Department because of persistent exertional dyspnea and peripheral edema. She had an established clinical diagnosis of hereditary hemorrhagic telangiectasia with multiple gastrointestinal telangiectasias that had been submitted to repeat embolization in the past and arteriovenous malformations in the liver and lungs. Complete blood count was diagnostic for severe anemia (hemoglobin 5-6 g/dL). Since the hereditary hemorrhagic telangiectasia diagnosis 3 years prior, the patient informed us that she has undergone 27 blood transfusions and multiple embolizations to manage gastrointestinal telangiectasias. Given her severe anemia that was caused by gastrointestinal telangiectasia, treatment with bevacizumab was initiated. Bevacizumab was administered over 8 cycles (initially biweekly for 4 doses, followed by monthly administration).
我们报告的情况下，45岁的妇女谁是转介到我们的心脏科，因为持续用力呼吸困难和周围水肿。她的临床诊断为遗传性出血性毛细血管扩张，并伴有多发性胃肠道毛细血管扩张，过去曾多次栓塞，肝和肺有动静脉畸形。全血细胞计数诊断严重贫血（血红蛋白5-6 g/dL）。自3年前诊断为遗传性出血性毛细血管扩张以来，患者告知我们，她接受了27次输血和多次栓塞治疗胃肠道毛细血管扩张。考虑到她因胃肠道毛细血管扩张引起的严重贫血，开始使用贝伐单抗治疗。贝伐单抗给药超过8个周期（最初是每两周给药4次，随后是每月给药）。
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引用次数: 0
Rebuttal From Drs Walter, Satterwhite, and Schmidt. 沃尔特、萨特怀特和施密特博士反驳
IF 9.6 1区 医学 Q1 CRITICAL CARE MEDICINE
Chest
Pub Date : 2026-01-01 DOI: 10.1016/j.chest.2025.07.4117
James M Walter,Lewis Satterwhite,Gregory A Schmidt
{"title":"Rebuttal From Drs Walter, Satterwhite, and Schmidt.","authors":"James M Walter,Lewis Satterwhite,Gregory A Schmidt","doi":"10.1016/j.chest.2025.07.4117","DOIUrl":"https://doi.org/10.1016/j.chest.2025.07.4117","url":null,"abstract":"","PeriodicalId":9782,"journal":{"name":"Chest","volume":"254 1","pages":"31-33"},"PeriodicalIF":9.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145947477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
COUNTERPOINT: Should Pulmonary and Critical Care Medicine Fellowship Training Programs Require Advanced Cardiac Point-of-Care Ultrasound Competency? No. 对应物：肺部和重症监护医学奖学金培训项目是否需要高级心脏护理点超声能力？否。
IF 9.6 1区 医学 Q1 CRITICAL CARE MEDICINE
Chest
Pub Date : 2026-01-01 DOI: 10.1016/j.chest.2025.07.4119
James M Walter,Lewis Satterwhite,Gregory A Schmidt
{"title":"COUNTERPOINT: Should Pulmonary and Critical Care Medicine Fellowship Training Programs Require Advanced Cardiac Point-of-Care Ultrasound Competency? No.","authors":"James M Walter,Lewis Satterwhite,Gregory A Schmidt","doi":"10.1016/j.chest.2025.07.4119","DOIUrl":"https://doi.org/10.1016/j.chest.2025.07.4119","url":null,"abstract":"","PeriodicalId":9782,"journal":{"name":"Chest","volume":"29 1","pages":"28-30"},"PeriodicalIF":9.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145947481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Response. 响应。
IF 8.6 1区 医学 Q1 CRITICAL CARE MEDICINE
Chest
Pub Date : 2026-01-01 DOI: 10.1016/j.chest.2025.09.004
Yeon Wook Kim
{"title":"Response.","authors":"Yeon Wook Kim","doi":"10.1016/j.chest.2025.09.004","DOIUrl":"https://doi.org/10.1016/j.chest.2025.09.004","url":null,"abstract":"","PeriodicalId":9782,"journal":{"name":"Chest","volume":"169 1","pages":"e38-e40"},"PeriodicalIF":8.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145948358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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