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Head-Up, Mucus Down: Why Patient Position May Matter More Than Oscillation. 头朝上,粘液朝下:为什么病人体位比摆动更重要。
IF 8.6 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2026-03-01 DOI: 10.1016/j.chest.2025.09.014
George Ntoumenopoulos
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引用次数: 0
Pleural Manometry in Tension Pneumothorax: A Step in Physiologic Precision. 张力性气胸胸膜测压:生理精确的一步。
IF 8.6 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2026-03-01 DOI: 10.1016/j.chest.2025.11.026
Alguili Elsheikh, Najib M Rahman
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引用次数: 0
Sharpening the Aim: A Needed Clarification of Diagnostic Yield in Bronchoscopy Research. 明确目标:支气管镜检查研究中诊断结果的需要澄清。
IF 9.6 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2026-03-01 DOI: 10.1016/j.chest.2025.09.013
Fabien Maldonado,Anne V Gonzalez,Lonny B Yarmus,Gerard A Silvestri
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引用次数: 0
Large Respiratory Swings: Are Average Pulmonary Pressure Values Throughout the Respiratory Cycle Enough? 大的呼吸波动:整个呼吸周期的平均肺压值是否足够?
IF 9.6 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2026-03-01 DOI: 10.1016/j.chest.2025.09.138
Juan C Grignola,Pedro Trujillo,Enric Domingo
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引用次数: 0
Diamond in the Rough or Just the Flavor of the Week?: Transforming Growth Factor 15 as a Biomarker in Pulmonary Arterial Hypertension. 未经加工的钻石还是本周的亮点?转化生长因子15作为肺动脉高压的生物标志物。
IF 9.6 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2026-03-01 DOI: 10.1016/j.chest.2025.11.030
Arun Jose
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引用次数: 0
Preserved Ratio Impaired Spirometry: A Treatable Trait Identified by Spirometry When Elevated Risk of Lung Cancer and Cardiovascular Death Coexist. 保留比例肺量测定受损:当肺癌和心血管死亡并存的高风险时,肺量测定确定了一种可治疗的特征。
IF 8.6 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2026-03-01 DOI: 10.1016/j.chest.2025.12.046
Robert P Young, Raewyn J Scott
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引用次数: 0
International Stakeholder Engagement on Clinical Care and Research for Sleep Assessment and Nocturnal Hypoxemia in Pulmonary Fibrosis. 国际利益相关者参与肺纤维化患者睡眠评估和夜间低氧血症的临床护理和研究。
IF 8.6 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2026-03-01 Epub Date: 2025-09-25 DOI: 10.1016/j.chest.2025.09.020
Leona Dowman, Shane Landry, Natasha Smallwood, Catharina Moor, Bradley A Edwards, Christopher J Ryerson, Christine F McDonald, Nicole S Goh, Harry Patsamanis, Lynne Cochrane, Simon Joosten, Marlies Wijsenbeek, Magnus Ekström, Sebastian V Moreno, Graham Hepworth, Anne E Holland, Yet H Khor

Background: Nocturnal hypoxemia commonly affects people with pulmonary fibrosis (PF).

Research question: What are the current practices for assessment of sleep and nocturnal hypoxemia in PF, and what are the research priorities and outcome measures of importance for nocturnal oxygen therapy (NOT)?

Study design and methods: People with PF and health care professionals (HCPs) with expertise in PF, sleep medicine, and/or oxygen therapy, were recruited internationally to participate in mixed-methods online surveys followed by online focus groups.

Results: A total of 68 people with PF and 73 HCPs from 29 countries completed the survey, with 14 and 39 joining the focus groups, respectively. Of these, 51% of people with PF had previous sleep assessment. In those that had not, 75% advocated its inclusion in routine PF management. Of HCPs, 64% performed sleep assessments routinely or as clinically indicated, with 82% reporting the assessments as very or somewhat important. The effect of treating nocturnal hypoxemia on symptom burden (including health-related quality of life) was considered the top research priority for people with PF and HCPs. Other research priorities identified were safety and tolerability of NOT, effect of treating nocturnal hypoxemia on mortality and pulmonary hypertension, diagnostic approaches for assessing sleep and nocturnal hypoxemia, predictors of nocturnal hypoxemia, developing a user-friendly oxygen therapy device, and patient awareness of the significance of nocturnal hypoxemia. Both groups prioritized health-related quality of life as the most important outcome measure for evaluating NOT. Additionally, people with PF highly ranked FVC, apnea-hypopnea index, and nocturnal oxygenation status, whereas HCPs selected survival and development of pulmonary hypertension. People with PF raised impact of nocturnal hypoxemia and sleep disturbance on cognitive performance as a key research topic, which was agreed by HCPs.

Interpretation: This study provides important insights into stakeholders' priorities to guide future research on sleep assessment and treatment of nocturnal hypoxemia in PF.

背景:夜间低氧血症常见于肺纤维化(PF)患者。问题:目前评估PF患者睡眠和夜间低氧血症的做法是什么?夜间氧疗(NOT)的重要研究重点和结果指标是什么?研究设计和方法:在全球范围内招募PF患者和具有PF、睡眠医学和/或氧气治疗专业知识的医疗保健专业人员(HCPs)参加混合方法的在线调查,随后是在线焦点小组。结果:来自29个国家的68名PF患者和73名hcp患者完成了调查,分别有14人和39人加入了焦点小组。51%的PF患者之前有过睡眠评估。在那些没有这样做的国家中,75%的人主张将其纳入日常的PF管理。64%的医护人员按常规或按临床指示进行睡眠评估,82%的人认为评估非常重要或有些重要。治疗夜间低氧血症对症状负担(包括健康相关生活质量[HRQoL])的影响被认为是PF和HCPs患者的首要研究重点。确定的其他研究重点包括:NOT的安全性和耐受性,治疗夜间低氧血症对死亡率和肺动脉高压的影响,评估睡眠和夜间低氧血症的诊断方法,夜间低氧血症的预测因素,开发用户友好的氧疗设备,以及患者对夜间低氧血症重要性的认识。两组均将HRQoL作为评估NOT的最重要结果指标。此外,PF患者在强迫肺活量、呼吸暂停-低通气指数和夜间氧合状态方面排名较高,而HCPs则选择肺动脉高压的生存和发展。PF患者将夜间低氧血症和睡眠障碍对认知表现的影响作为一个重点研究课题,这得到了HCPs的认同。解释:这项研究为利益相关者的优先事项提供了重要的见解,以指导未来PF患者睡眠评估和夜间低氧血症治疗的研究。
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引用次数: 0
Rethinking Smoking: Cannabis, Tobacco, and Lung Cancer. 重新思考吸烟:大麻、烟草和肺癌。
IF 8.6 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2026-03-01 DOI: 10.1016/j.chest.2025.11.014
Jesse T Kaye, Hasmeena Kathuria
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引用次数: 0
Clamping the Chest Tube: Always Or Never? - Beware the Flaws of Binary Thinking! 夹胸管:要还是不要?-谨防二元思维的缺陷!
IF 8.6 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2026-03-01 DOI: 10.1016/j.chest.2025.11.025
Karan Singh, Septimiu Dan Murgu
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引用次数: 0
A Comment on "The Effects of Low-Dose Morphine on Sleep and Breathlessness in COPD". 关于“低剂量吗啡对慢性阻塞性肺病患者睡眠和呼吸困难的影响”的评论。
IF 9.6 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2026-03-01 DOI: 10.1016/j.chest.2025.07.4129
Yushi Shimamura,Takuma Ikeda,Satoru Terada
{"title":"A Comment on \"The Effects of Low-Dose Morphine on Sleep and Breathlessness in COPD\".","authors":"Yushi Shimamura,Takuma Ikeda,Satoru Terada","doi":"10.1016/j.chest.2025.07.4129","DOIUrl":"https://doi.org/10.1016/j.chest.2025.07.4129","url":null,"abstract":"","PeriodicalId":9782,"journal":{"name":"Chest","volume":"55 1","pages":"e115-e116"},"PeriodicalIF":9.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147393991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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