Pub Date : 2023-07-25DOI: 10.3329/cmoshmcj.v22i1.67836
Md. Saiful Islam, Papri Dutta, N. Dey, M. Kabir
Background: In the age of assisted reproduction, search for the cause of male infertility is increasing in numbers. As finding of obstructive azoospermia give the male a hope there are increased requisition to the cytopathologist to evaluate the spermatogenesis status of a male. The aim of the study was to see the cytomorphological pattern in azoospermia patients and to determine the procedure's safety. Materials and methods: From January 2015 to June 2022, in Chattogram, Bangladesh, 395 patients with azoospermia were taken in this descriptive study. After all aseptic precautions and local anesthetization aspiration was done from both testes. Cytomorphological analysis was done in the following classes i) Positive for spermatogenesis ii) Hypo-spermatogenesis iii) Early maturation arrest iv) Late maturation arrest v) Sertoli cell only vi) Atrophic. Results: Cytological diagnosis yielded 161 (40.76%) positive for spermatogenesis, indicating obstructive azoospermia, seconded by 'Sertoli cell only' in 115 (29.11%) patients. Both conditions were highest in the age group of 31-40, 93(57.76%) and 72 (62.6%). Hematoma was seen in 04(1.01%) cases and extended period of pain was experienced by 05 (1.26%) patients. Conclusion: FNA of the testis is a much simpler and easily accessible procedure to assess the spermatogenesis status of an azoospermia patient. Chatt Maa Shi Hosp Med Coll J; Vol.22 (1); January 2023; Page 53-56
{"title":"Cytological Findings in Testicular FNAC in Azoospermia Patient: A Study of 395 Cases","authors":"Md. Saiful Islam, Papri Dutta, N. Dey, M. Kabir","doi":"10.3329/cmoshmcj.v22i1.67836","DOIUrl":"https://doi.org/10.3329/cmoshmcj.v22i1.67836","url":null,"abstract":"Background: In the age of assisted reproduction, search for the cause of male infertility is increasing in numbers. As finding of obstructive azoospermia give the male a hope there are increased requisition to the cytopathologist to evaluate the spermatogenesis status of a male. The aim of the study was to see the cytomorphological pattern in azoospermia patients and to determine the procedure's safety. \u0000Materials and methods: From January 2015 to June 2022, in Chattogram, Bangladesh, 395 patients with azoospermia were taken in this descriptive study. After all aseptic precautions and local anesthetization aspiration was done from both testes. Cytomorphological analysis was done in the following classes i) Positive for spermatogenesis ii) Hypo-spermatogenesis iii) Early maturation arrest iv) Late maturation arrest v) Sertoli cell only vi) Atrophic. \u0000Results: Cytological diagnosis yielded 161 (40.76%) positive for spermatogenesis, indicating obstructive azoospermia, seconded by 'Sertoli cell only' in 115 (29.11%) patients. Both conditions were highest in the age group of 31-40, 93(57.76%) and 72 (62.6%). Hematoma was seen in 04(1.01%) cases and extended period of pain was experienced by 05 (1.26%) patients. \u0000Conclusion: FNA of the testis is a much simpler and easily accessible procedure to assess the spermatogenesis status of an azoospermia patient. \u0000Chatt Maa Shi Hosp Med Coll J; Vol.22 (1); January 2023; Page 53-56","PeriodicalId":9788,"journal":{"name":"Chattagram Maa-O-Shishu Hospital Medical College Journal","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85665582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-25DOI: 10.3329/cmoshmcj.v22i1.67840
F. Ara, Zabeen Choudhury, S. Hasan, Mosammat Zebunnesa, Rasheda Samad
Background: Sodium disturbances, either hyponatremia or hypernatremia, are the most common electrolyte imbalance encountered in managing children with acute watery diarrhoea. Early diagnosis and prompt management of these conditions by identifying clinical predicting factors in diarrheal children under 5 years of age are critically essential to prevent deaths in such children, especially in resource-limited settings. Our study aimed to evaluate clinical predicting factors associated with sodium disturbance in children hospitalized with acute watery diarrhea. Materials and Methods: In this cross-sectional study, 121 children of 2 months to 5 years of age admitted in the Department of Pediatrics, Chittagong Medical College Hospital, Chattogram for acute watery diarrhea were included. Clinical features and sodium levels on admission were recorded. Children were grouped in hyponatremia (serum sodium <135mmol/l), hypernatremia (serum sodium >145mmol/l) and normonatremia (serum sodium 135–145mmol/l) and compared. Results: Of the 121 children, 18 (14.9%) were hyponatremic, 71 (58.7%) isonatraemic, and 32 (26.4%) hypernatraemic. Logistic regression analysis revealed that children who did not receive ORS before admission, had severe dehydration and lethargy on admission would be more likely to have hyponatremic dehydration. Children who were younger, received concentrated ORS, thirsty and had convulsions on admission would be more likely to have hypernatremic dehydration than children with isonatremia. Conclusion: The type of ORS used and age appears to be good predictors of sodium disturbance in children admitted with AWD. Chatt Maa Shi Hosp Med Coll J; Vol.22 (1); January 2023; Page 71-75
{"title":"Clinical Predictors of Sodium Disturbance in Children Presenting with Acute Watery Diarrhea in a Tertiary Hospital of Bangladesh","authors":"F. Ara, Zabeen Choudhury, S. Hasan, Mosammat Zebunnesa, Rasheda Samad","doi":"10.3329/cmoshmcj.v22i1.67840","DOIUrl":"https://doi.org/10.3329/cmoshmcj.v22i1.67840","url":null,"abstract":"Background: Sodium disturbances, either hyponatremia or hypernatremia, are the most common electrolyte imbalance encountered in managing children with acute watery diarrhoea. Early diagnosis and prompt management of these conditions by identifying clinical predicting factors in diarrheal children under 5 years of age are critically essential to prevent deaths in such children, especially in resource-limited settings. Our study aimed to evaluate clinical predicting factors associated with sodium disturbance in children hospitalized with acute watery diarrhea. \u0000Materials and Methods: In this cross-sectional study, 121 children of 2 months to 5 years of age admitted in the Department of Pediatrics, Chittagong Medical College Hospital, Chattogram for acute watery diarrhea were included. Clinical features and sodium levels on admission were recorded. Children were grouped in hyponatremia (serum sodium <135mmol/l), hypernatremia (serum sodium >145mmol/l) and normonatremia (serum sodium 135–145mmol/l) and compared. \u0000Results: Of the 121 children, 18 (14.9%) were hyponatremic, 71 (58.7%) isonatraemic, and 32 (26.4%) hypernatraemic. Logistic regression analysis revealed that children who did not receive ORS before admission, had severe dehydration and lethargy on admission would be more likely to have hyponatremic dehydration. Children who were younger, received concentrated ORS, thirsty and had convulsions on admission would be more likely to have hypernatremic dehydration than children with isonatremia. \u0000Conclusion: The type of ORS used and age appears to be good predictors of sodium disturbance in children admitted with AWD. \u0000Chatt Maa Shi Hosp Med Coll J; Vol.22 (1); January 2023; Page 71-75","PeriodicalId":9788,"journal":{"name":"Chattagram Maa-O-Shishu Hospital Medical College Journal","volume":"300 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75112248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-25DOI: 10.3329/cmoshmcj.v22i1.67841
A. Malik
Background: Abdominal pregnancy is a rare form of ectopic or extrauterine pregnancy with an incidence of 1:10000 and 1:30000. Advanced abdominal pregnancy is extremely rare with high maternal and perinatal mortality. Case Presentation: We report a case of abdominal pregnancy at 32 weeks gestation with persistent abdominal pain and severe anemia, who was referred from another hospital to our center with an Ultrasonogram, missed the diagnosis of abdominal pregnancy, which was confirmed in our center as abdominal pregnancy at 32 weeks with live fetus. With laparotomy a 1.2 kg female baby was born without much difficulty and post operative recovery was uneventful. But the baby died at 27Th post operative day. Conclusion: High index of clinical suspicion is necessary for early diagnosis of abdominal pregnancy and timely laparotomy with multidisciplinary surgical team can save the life of a mother. Chatt Maa Shi Hosp Med Coll J; Vol.22 (1); January 2023; Page 76-78
{"title":"Advanced Abdominal Pregnancy of 32 Weeks with Alive Baby: A Rare Event","authors":"A. Malik","doi":"10.3329/cmoshmcj.v22i1.67841","DOIUrl":"https://doi.org/10.3329/cmoshmcj.v22i1.67841","url":null,"abstract":"Background: Abdominal pregnancy is a rare form of ectopic or extrauterine pregnancy with an incidence of 1:10000 and 1:30000. Advanced abdominal pregnancy is extremely rare with high maternal and perinatal mortality. \u0000Case Presentation: We report a case of abdominal pregnancy at 32 weeks gestation with persistent abdominal pain and severe anemia, who was referred from another hospital to our center with an Ultrasonogram, missed the diagnosis of abdominal pregnancy, which was confirmed in our center as abdominal pregnancy at 32 weeks with live fetus. With laparotomy a 1.2 kg female baby was born without much difficulty and post operative recovery was uneventful. But the baby died at 27Th post operative day. \u0000Conclusion: High index of clinical suspicion is necessary for early diagnosis of abdominal pregnancy and timely laparotomy with multidisciplinary surgical team can save the life of a mother. \u0000Chatt Maa Shi Hosp Med Coll J; Vol.22 (1); January 2023; Page 76-78","PeriodicalId":9788,"journal":{"name":"Chattagram Maa-O-Shishu Hospital Medical College Journal","volume":"71 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75979894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Epilepsy is one of the most common neurological morbidities in children worldwide. Anti-Seizure Medication (ASM) is the mainstay of epilepsy treatment. Adherence to Anti-Seizure Medication (ASM) is the key to achieving seizure remission. So this study aimed to assess the adherence to anti-seizure medication among children with epilepsy and to identify the factors that influence adherence. Materials and methods: It was a cross-sectional study involving Infants and children aged six months to twelve years old with seizure disorder irrespective of etiology, taking anti-seizure medications for more than six months and receiving mono or polytherapy were enrolled as the study subject. Self-reporting measures were used to assess adherence. Patients' caregivers were interviewed for the assessment of adherence. Descriptive statistical analysis was used to analyze the data, and univariate analysis with a chi-square test was used to observe the association between the variables and adherence. Results: The mean±SD age of the participants was 34.75 ± 38.39 months. A significant association was found between the age of the respondent and compliance with anti-seizure medication (30.5± 27.25 vs. 39.99±36.67 months p=0.012). Males were more than females 28(70%) Vs. 12(30%). Most of the study subjects were belonging to lower-middle-class families 13(33.3%). The generalized onset of seizure was the frequent type of seizure 28(70%). The majority of the participants 24 (60%) did have a seizure with structural etiology. Most of the study subjects received monotherapy 34(85%). Sodium valproate 19(47.5%) was the most frequently used drug. Seizure remission was found in 28(70%) of the study population. No significant association was found between the treatment outcome and adherence to antiseizure medication (ASM). Adherence to ASM was found in 55% of this study. Unable to afford cost was found to be the main cause of non-adherence 14(35%). There is a significant association found between the duration of taking ASM and compliance with ASM (7.05 ± 5.3 vs. 17.56± 15.43 months p=0.005). Conclusion: Adherence to Anti-Seizure Medication (ASM) is low in our study. Unable to afford cost was the main factor accountable for non-adherence appropriate interventions are needed to improve ASM compliance and consequently treatment outcome. Chatt Maa Shi Hosp Med Coll J; Vol.22 (1); January 2023; Page 38-43
背景:癫痫是全世界儿童最常见的神经系统疾病之一。抗癫痫药物(ASM)是治疗癫痫的主要手段。坚持抗癫痫药物治疗(ASM)是实现癫痫发作缓解的关键。因此，本研究旨在评估癫痫儿童抗癫痫药物的依从性，并确定影响依从性的因素。材料与方法:本研究是一项横断面研究，纳入6个月至12岁的婴儿和儿童，不论病因，患有癫痫发作障碍，服用抗癫痫药物6个月以上，接受单一或多种治疗。采用自我报告方法评估依从性。对患者的护理人员进行访谈以评估依从性。资料分析采用描述性统计分析，单因素分析采用卡方检验观察各变量与依从性的相关性。结果:参与者的平均±SD年龄为34.75±38.39个月。患者年龄与抗癫痫药物依从性之间存在显著相关性(30.5±27.25 vs 39.99±36.67个月p=0.012)。男性多于女性28例(70%)Vs. 12例(30%)。大多数研究对象属于中下层家庭13(33.3%)。全身性癫痫发作为频繁发作类型28例(70%)。大多数参与者24(60%)确实有结构性病因的癫痫发作。大多数研究对象接受单一疗法34(85%)。丙戊酸钠19(47.5%)是最常用的药物。研究人群中有28人(70%)癫痫发作缓解。治疗结果与抗癫痫药物(ASM)依从性之间无显著关联。在这项研究中，55%的人坚持使用ASM。负担不起费用被发现是不遵守规定的主要原因14(35%)。服药时间与服药依从性之间存在显著相关性(7.05±5.3个月vs. 17.56±15.43个月p=0.005)。结论:本研究中抗癫痫药物的依从性较低。负担不起费用是导致不依从性的主要因素，需要采取适当的干预措施来提高ASM的依从性，从而提高治疗效果。上海医科大学医学院;工程系(1);2023年1月;页面中山
{"title":"Adherence to Anti-Seizure Medications in Children with Epilepsy Attending a Tertiary Care Center in Bangladesh","authors":"Dhananjoy Das, Wahida Akther, Tanuka Barua, Rehena Ahmed, Nazrul Quader Shikder, M. Chowdhury","doi":"10.3329/cmoshmcj.v22i1.67833","DOIUrl":"https://doi.org/10.3329/cmoshmcj.v22i1.67833","url":null,"abstract":"Background: Epilepsy is one of the most common neurological morbidities in children worldwide. Anti-Seizure Medication (ASM) is the mainstay of epilepsy treatment. Adherence to Anti-Seizure Medication (ASM) is the key to achieving seizure remission. So this study aimed to assess the adherence to anti-seizure medication among children with epilepsy and to identify the factors that influence adherence. \u0000Materials and methods: It was a cross-sectional study involving Infants and children aged six months to twelve years old with seizure disorder irrespective of etiology, taking anti-seizure medications for more than six months and receiving mono or polytherapy were enrolled as the study subject. Self-reporting measures were used to assess adherence. Patients' caregivers were interviewed for the assessment of adherence. Descriptive statistical analysis was used to analyze the data, and univariate analysis with a chi-square test was used to observe the association between the variables and adherence. \u0000Results: The mean±SD age of the participants was 34.75 ± 38.39 months. A significant association was found between the age of the respondent and compliance with anti-seizure medication (30.5± 27.25 vs. 39.99±36.67 months p=0.012). Males were more than females 28(70%) Vs. 12(30%). Most of the study subjects were belonging to lower-middle-class families 13(33.3%). The generalized onset of seizure was the frequent type of seizure 28(70%). The majority of the participants 24 (60%) did have a seizure with structural etiology. Most of the study subjects received monotherapy 34(85%). Sodium valproate 19(47.5%) was the most frequently used drug. Seizure remission was found in 28(70%) of the study population. No significant association was found between the treatment outcome and adherence to antiseizure medication (ASM). Adherence to ASM was found in 55% of this study. Unable to afford cost was found to be the main cause of non-adherence 14(35%). There is a significant association found between the duration of taking ASM and compliance with ASM (7.05 ± 5.3 vs. 17.56± 15.43 months p=0.005). \u0000Conclusion: Adherence to Anti-Seizure Medication (ASM) is low in our study. Unable to afford cost was the main factor accountable for non-adherence appropriate interventions are needed to improve ASM compliance and consequently treatment outcome. \u0000Chatt Maa Shi Hosp Med Coll J; Vol.22 (1); January 2023; Page 38-43","PeriodicalId":9788,"journal":{"name":"Chattagram Maa-O-Shishu Hospital Medical College Journal","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88260511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-25DOI: 10.3329/cmoshmcj.v22i1.67831
Rosanna Bintey Kamal
Background: The comparative safety of immunosuppressive drugs such as cyclophosphamide and mycophenolate mofetil for patients with lupus nephritis remains controversial. The study aimed to investigate the specific side effects of cyclophosphamide and mycophenolate mofetil in lupus nephritis patient after induction treatment. Materials and methods: It was a quasi-experimental study performed in the Department of Nephrology of Chittagong Medical College Hospital. A total of 100 patients of lupus nephritis who fulfilled the designated criteria were enrolled in this study by non-probability voluntary sampling method. The treatment was given on patient’s choice. After screening and treatment initiation, patients were assessed at 12 and 24 weeks. All the data were compiled in a structured case record form. Results: In the present study 48 patients (53.3%) in mycophenolate mofetil group and 42 patients (46.7%) in intravenous cyclophosphamide group completed 24 weeks of induction treatment of lupus nephritis. Infections were common in both treatment groups but significantly higher with intravenous cyclophosphamide group ((33.3% vs. 8.3%). Upper gastrointestinal syndrome occurred with 20(41%) patients in mycophenolate mofetil group and 7(16.7%) patients in intravenous cyclophosphamide group (RR=5.8333). Regarding other adverse effect, 10 patients of intravenous cyclophosphamide and two patients of mycophenolate mofetil group had amenorrhea (23.8% vs.4.2%). Alopecia (11.9%) was seen only by intravenous cyclophosphamide group ((RR=0.0798). Conclusion: Induction therapy with Mycophenolate mofetil was superior to intravenous cyclophosphamide in lupus nephritis in this study. Mycophenolate mofetil appeared to be better tolerated than cyclophosphamide. Chatt Maa Shi Hosp Med Coll J; Vol.22 (1); January 2023; Page 28-32
背景:免疫抑制药物如环磷酰胺和霉酚酸酯治疗狼疮性肾炎患者的相对安全性仍存在争议。本研究旨在探讨环磷酰胺和霉酚酸酯在狼疮性肾炎患者诱导治疗后的特异性副作用。材料与方法:在吉大港医学院附属医院肾内科进行准实验研究。采用非概率自愿抽样的方法，对100例符合指定标准的狼疮性肾炎患者进行研究。根据病人的选择给予治疗。在筛查和治疗开始后，患者在12周和24周进行评估。所有数据以结构化病例记录形式汇编。结果:本研究中，霉酚酸酯组48例(53.3%)，环磷酰胺组42例(46.7%)完成了24周狼疮性肾炎诱导治疗。两组患者均有感染，但静脉注射环磷酰胺组感染率明显高于对照组(33.3% vs. 8.3%)。霉酚酸酯组出现上消化道综合征20例(41%)，静脉环磷酰胺组出现上消化道综合征7例(16.7%)(RR=5.8333)。其他不良反应方面，静脉注射环磷酰胺组10例闭经，霉酚酸酯组2例闭经(23.8% vs.4.2%)。仅静脉注射环磷酰胺组出现脱发(11.9%)(RR=0.0798)。结论:应用霉酚酸酯诱导治疗狼疮性肾炎优于静脉注射环磷酰胺。霉酚酸酯似乎比环磷酰胺耐受性更好。上海医科大学医学院;工程系(1);2023年1月;页面28-32
{"title":"Risk Assessment of Cyclophosphamide and Mycophenolate Mofetil after Induction Treatment of Lupus Nephritis: A Single Center Quasi-Experimental Study","authors":"Rosanna Bintey Kamal","doi":"10.3329/cmoshmcj.v22i1.67831","DOIUrl":"https://doi.org/10.3329/cmoshmcj.v22i1.67831","url":null,"abstract":"Background: The comparative safety of immunosuppressive drugs such as cyclophosphamide and mycophenolate mofetil for patients with lupus nephritis remains controversial. The study aimed to investigate the specific side effects of cyclophosphamide and mycophenolate mofetil in lupus nephritis patient after induction treatment. \u0000Materials and methods: It was a quasi-experimental study performed in the Department of Nephrology of Chittagong Medical College Hospital. A total of 100 patients of lupus nephritis who fulfilled the designated criteria were enrolled in this study by non-probability voluntary sampling method. The treatment was given on patient’s choice. After screening and treatment initiation, patients were assessed at 12 and 24 weeks. All the data were compiled in a structured case record form. \u0000Results: In the present study 48 patients (53.3%) in mycophenolate mofetil group and 42 patients (46.7%) in intravenous cyclophosphamide group completed 24 weeks of induction treatment of lupus nephritis. Infections were common in both treatment groups but significantly higher with intravenous cyclophosphamide group ((33.3% vs. 8.3%). Upper gastrointestinal syndrome occurred with 20(41%) patients in mycophenolate mofetil group and 7(16.7%) patients in intravenous cyclophosphamide group (RR=5.8333). Regarding other adverse effect, 10 patients of intravenous cyclophosphamide and two patients of mycophenolate mofetil group had amenorrhea (23.8% vs.4.2%). Alopecia (11.9%) was seen only by intravenous cyclophosphamide group ((RR=0.0798). \u0000Conclusion: Induction therapy with Mycophenolate mofetil was superior to intravenous cyclophosphamide in lupus nephritis in this study. Mycophenolate mofetil appeared to be better tolerated than cyclophosphamide. \u0000Chatt Maa Shi Hosp Med Coll J; Vol.22 (1); January 2023; Page 28-32","PeriodicalId":9788,"journal":{"name":"Chattagram Maa-O-Shishu Hospital Medical College Journal","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88725393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-08DOI: 10.3329/cmoshmcj.v21i2.63127
Ashfaq Nabi, A. Hanif, K. Hasina, J. Khan, N. Khan, Nazmul Hasan
Background: Cystic lymphangioma is a congenital lymphatic malformation.The present study was conducted to find out the effects of intralesional Doxycycline in the treatment of cystic hygroma. Materials and methods: This prospective study was conducted among 30 children with cystic hygroma in the Division of Pediatric Surgery, Dhaka Medical college Hospital, Dhaka, from July 2019 to June 2021. All patients were followed up for six months. In every follow up size of the lesion was determined and adverse effects were also noted. Results: More than half of the cystic hygroma (53.3%) were in neck while 5 (16.6%) in axilla. Before treatment, the median size of cystic hygroma was 12.00 cm2 which significantly decreased to 0.75cm2after treatment (p<0.001). After treatment, 83.3% participants showed excellent response and 16.6% participants showed good response. Out of 30 patients, 33.3% had adverse effects which included pain (n=5), redness of skin (n=5), fever (n=5) and skin pigmentation (n=2). Conclusion: Doxycycline monotherapy resulted in a high rate of excellent clinical outcomes after a few treatments without increased need for subsequent operative resection. It was very cost effective also. Chatt Maa Shi Hosp Med Coll J; Vol.21 (2); July 2022; Page 40-43
{"title":"Effects of Intralesional Doxycycline in the Treatment of Cystic Hygroma","authors":"Ashfaq Nabi, A. Hanif, K. Hasina, J. Khan, N. Khan, Nazmul Hasan","doi":"10.3329/cmoshmcj.v21i2.63127","DOIUrl":"https://doi.org/10.3329/cmoshmcj.v21i2.63127","url":null,"abstract":"Background: Cystic lymphangioma is a congenital lymphatic malformation.The present study was conducted to find out the effects of intralesional Doxycycline in the treatment of cystic hygroma. \u0000Materials and methods: This prospective study was conducted among 30 children with cystic hygroma in the Division of Pediatric Surgery, Dhaka Medical college Hospital, Dhaka, from July 2019 to June 2021. All patients were followed up for six months. In every follow up size of the lesion was determined and adverse effects were also noted. \u0000Results: More than half of the cystic hygroma (53.3%) were in neck while 5 (16.6%) in axilla. Before treatment, the median size of cystic hygroma was 12.00 cm2 which significantly decreased to 0.75cm2after treatment (p<0.001). After treatment, 83.3% participants showed excellent response and 16.6% participants showed good response. Out of 30 patients, 33.3% had adverse effects which included pain (n=5), redness of skin (n=5), fever (n=5) and skin pigmentation (n=2). \u0000Conclusion: Doxycycline monotherapy resulted in a high rate of excellent clinical outcomes after a few treatments without increased need for subsequent operative resection. It was very cost effective also. \u0000Chatt Maa Shi Hosp Med Coll J; Vol.21 (2); July 2022; Page 40-43","PeriodicalId":9788,"journal":{"name":"Chattagram Maa-O-Shishu Hospital Medical College Journal","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83495263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-08DOI: 10.3329/cmoshmcj.v21i2.63155
M. J. Uddin
Abstract not available Chatt Maa Shi Hosp Med Coll J; Vol.21 (2); July 2022; Page 68
[摘要]上海医科大学医学院;月,(2);2022年7月;68页
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Pub Date : 2022-12-08DOI: 10.3329/cmoshmcj.v21i2.63090
Shahin Akhter, Md Sakhawat Mahmud Khan, M. Akhter, Arunima Datta, M. Begum
Background: Cement dust is one of the major air pollutants and its exposure causes various problems. It has deleterious effect on vital organs and may affect liver function. This study was done to assess the effects of cement dust on liver function parameters of cement factory workers. Materials and methods: This case control study was conducted in the Department of Physiology, Chittagong Medical College, Chattogram in collaboration with Heidelberg Cement Bangladesh Ltd. Chattogram during January 2018 to December 2018. For these, 30 cement exposed workers of Heidelberg Cement Bangladesh Ltd. aged between 20-45 years were included as case group. Age and sex matched 30 subjects were selected from office workers of Heidelberg Cement Bangladesh Ltd. and Chittagong Medical College as control group. To assess liver function 3 ml of venous blood was collected from each subject under aseptic precaution. Liver enzymes were assessed. After compiling data, statistical analyses were done by using SPSS for windows version-25. Unpaired student’s‘t’ test was done as test of significance. Results: Liver enzymes like serum AST and serum ALT was lower in case group than control group within normal range and it was not statistically significant. Serum ALT was significantly higher in case group than control. It was also within normal range. Conclusion: This study suggests that liver function might not be impaired by cement dust. Chatt Maa Shi Hosp Med Coll J; Vol.21 (2); July 2022; Page 22-24
背景:水泥粉尘是主要的大气污染物之一，其暴露会引起各种问题。它对重要器官有有害影响，并可能影响肝功能。本研究旨在评估水泥粉尘对水泥厂工人肝功能参数的影响。材料和方法:本病例对照研究在吉大港医学院生理学系进行，Chattogram与海德堡水泥孟加拉国有限公司合作。2018年1月至2018年12月期间的Chattogram。本研究以海德堡水泥孟加拉国有限公司30名年龄在20-45岁之间的水泥暴露工人为病例组。选取年龄、性别相匹配的海德堡水泥孟加拉国有限公司和吉大港医学院办公室职员30名作为对照组。为评估肝功能，每位受试者在无菌预防下采集静脉血3ml。评估肝酶。数据整理后，采用SPSS for windows version-25进行统计分析。Unpaired student’t检验作为显著性检验。结果:病例组血清AST、ALT等肝酶在正常范围内低于对照组，差异无统计学意义。病例组血清ALT显著高于对照组。它也在正常范围内。结论:本研究提示水泥粉尘可能不会损害肝功能。上海医科大学医学院;月,(2);2022年7月;第22 - 24页
{"title":"Effects of Cement Dust on Liver Function Parameters of Some Cement Factory Workers","authors":"Shahin Akhter, Md Sakhawat Mahmud Khan, M. Akhter, Arunima Datta, M. Begum","doi":"10.3329/cmoshmcj.v21i2.63090","DOIUrl":"https://doi.org/10.3329/cmoshmcj.v21i2.63090","url":null,"abstract":"Background: Cement dust is one of the major air pollutants and its exposure causes various problems. It has deleterious effect on vital organs and may affect liver function. This study was done to assess the effects of cement dust on liver function parameters of cement factory workers. \u0000Materials and methods: This case control study was conducted in the Department of Physiology, Chittagong Medical College, Chattogram in collaboration with Heidelberg Cement Bangladesh Ltd. Chattogram during January 2018 to December 2018. For these, 30 cement exposed workers of Heidelberg Cement Bangladesh Ltd. aged between 20-45 years were included as case group. Age and sex matched 30 subjects were selected from office workers of Heidelberg Cement Bangladesh Ltd. and Chittagong Medical College as control group. To assess liver function 3 ml of venous blood was collected from each subject under aseptic precaution. Liver enzymes were assessed. After compiling data, statistical analyses were done by using SPSS for windows version-25. Unpaired student’s‘t’ test was done as test of significance. \u0000Results: Liver enzymes like serum AST and serum ALT was lower in case group than control group within normal range and it was not statistically significant. Serum ALT was significantly higher in case group than control. It was also within normal range. \u0000Conclusion: This study suggests that liver function might not be impaired by cement dust. \u0000Chatt Maa Shi Hosp Med Coll J; Vol.21 (2); July 2022; Page 22-24","PeriodicalId":9788,"journal":{"name":"Chattagram Maa-O-Shishu Hospital Medical College Journal","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81238823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background : Apert syndrome is a rare autosomal dominant disorder characterized by craniosynostosis, facial dysmorphism and syndactyly of hands and feet. Eugene Apert in 1906 describe the syndrome acrocephalosyndactyly. Case Presentation : The reporting case was a 3 months old female baby presented with early fusion of all cranial bone, facial dimorphism like hypertelorism, cleft palate and syndactyly of both hands and feet. There was some bony defect also found in radioligy. Conclusion : It is a noncurable disease but treat with multidisciplinary approach can reduce the complication and prevention can be done by genetic counselling and antenatal ultrasonography. Chatt Maa Shi Hosp Med Coll J; Vol.21 (2); July 2022; Page 60-63
{"title":"Apert Syndrome: A Case Report","authors":"R. Chowdhury, Md. Akram Ullah, Shirin Akhter Ruhina, Fahmida Jahan Gazi, Tanuka Barua, Priyanka Chowdhury","doi":"10.3329/cmoshmcj.v21i2.63142","DOIUrl":"https://doi.org/10.3329/cmoshmcj.v21i2.63142","url":null,"abstract":"Background : Apert syndrome is a rare autosomal dominant disorder characterized by craniosynostosis, facial dysmorphism and syndactyly of hands and feet. Eugene Apert in 1906 describe the syndrome acrocephalosyndactyly. \u0000Case Presentation : The reporting case was a 3 months old female baby presented with early fusion of all cranial bone, facial dimorphism like hypertelorism, cleft palate and syndactyly of both hands and feet. There was some bony defect also found in radioligy. \u0000Conclusion : It is a noncurable disease but treat with multidisciplinary approach can reduce the complication and prevention can be done by genetic counselling and antenatal ultrasonography. \u0000Chatt Maa Shi Hosp Med Coll J; Vol.21 (2); July 2022; Page 60-63 ","PeriodicalId":9788,"journal":{"name":"Chattagram Maa-O-Shishu Hospital Medical College Journal","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88594228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Patients with type II diabetes mellitus frequently have altered lipid profiles. Detection of serum high sensitivity C-reactive protein is associated with cardiovascular events in type II DM as the presence of subclinical inflammation. The study was undertaken to observe the fasting serum lipid profile level and its association with serum hs-CRP in type II DM. Materials and methods: A hospital-based observational study was carried out in the Outpatient Department of Endocrinology, Chittagong Medical College Hospital and Department of Biochemistry, Chittagong Medical College. By using non-probability consecutive sampling, a total of 176 participants were enrolled, with 126 type II DM and 50 in the control group. Plasma glucose and serum hs-CRP, fasting serum lipid profile was estimated. Results: The mean serum hs-CRP level in patients with type II DM (9.1 ± 0.36 mg/L) was significantly (p 0.0001) elevated as compared to control (4.3 ± 0.09 mg/L). The result showed an increase in serum total cholesterol, serum triglycerides, serum HDLC and serum LDL-C among the diabetic patients when compared with the healthy control group. Serum hs-CRP was significantly associated with serum TG and serum LDL-C in type II diabetics. Moreover, serum hs-CRP was found to have a significant positive correlation with serum LDL-C and serum TG. Only 77.78% of patients had increased LDL-C but altogether 85.71% of patients had increased serum hs-CRP levels. Conclusion: According to the findings of this study,increased serum hs-CRP was well associated and positively correlated with components of the fasting lipid profile, indicating early identification of cardiovascular risk among type II diabetics. Chatt Maa Shi Hosp Med Coll J; Vol.21 (2); July 2022; Page 35-39
{"title":"Fasting Serum Lipid Profile and Its Association with Serum High Sensitivity C-Reactive Protein in Type II Diabetes Mellitus","authors":"Nadia Hossain, Farhena Ahmed, Tasmia Sharnin, Pijush Karmakar","doi":"10.3329/cmoshmcj.v21i2.63126","DOIUrl":"https://doi.org/10.3329/cmoshmcj.v21i2.63126","url":null,"abstract":"Background: Patients with type II diabetes mellitus frequently have altered lipid profiles. Detection of serum high sensitivity C-reactive protein is associated with cardiovascular events in type II DM as the presence of subclinical inflammation. The study was undertaken to observe the fasting serum lipid profile level and its association with serum hs-CRP in type II DM. \u0000Materials and methods: A hospital-based observational study was carried out in the Outpatient Department of Endocrinology, Chittagong Medical College Hospital and Department of Biochemistry, Chittagong Medical College. By using non-probability consecutive sampling, a total of 176 participants were enrolled, with 126 type II DM and 50 in the control group. Plasma glucose and serum hs-CRP, fasting serum lipid profile was estimated. \u0000Results: The mean serum hs-CRP level in patients with type II DM (9.1 ± 0.36 mg/L) was significantly (p 0.0001) elevated as compared to control (4.3 ± 0.09 mg/L). The result showed an increase in serum total cholesterol, serum triglycerides, serum HDLC and serum LDL-C among the diabetic patients when compared with the healthy control group. Serum hs-CRP was significantly associated with serum TG and serum LDL-C in type II diabetics. Moreover, serum hs-CRP was found to have a significant positive correlation with serum LDL-C and serum TG. Only 77.78% of patients had increased LDL-C but altogether 85.71% of patients had increased serum hs-CRP levels. \u0000Conclusion: According to the findings of this study,increased serum hs-CRP was well associated and positively correlated with components of the fasting lipid profile, indicating early identification of cardiovascular risk among type II diabetics. \u0000Chatt Maa Shi Hosp Med Coll J; Vol.21 (2); July 2022; Page 35-39","PeriodicalId":9788,"journal":{"name":"Chattagram Maa-O-Shishu Hospital Medical College Journal","volume":"109 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86022595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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