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Gallstone Ileus: A Rare Surgical Emergency 胆结石性肠梗阻:一种罕见的外科急诊
Pub Date : 2022-12-08 DOI: 10.3329/cmoshmcj.v21i2.63141
A. Ullah, Md Muzharul Hoq Nasim, A. Salam, Maen Tayeb
Background : Gallstone ileus is a rare complication of cholelithiasis and is an uncommon cause of intestinal obstruction accounting for 1%–4% of mechanical bowel obstructions. This usually results from luminal impaction of one or more gallstone. Case Presentation : A 86-year-old male presented with the history of bilious vomiting for 15 days and abdominal distension for 8 days and diagnosed as a case of intestinal obstruction due to gall stone ileus. He was treated surgically by laparotomy followed by enterotomy and removal of gall stone were performed from the proximal ileum. Conclusion : Early diagnosis and treatment are important otherwise adverse effect of mechanical bowel obstruction leads to bad prognosis. Chatt Maa Shi Hosp Med Coll J; Vol.21 (2); July 2022; Page 57-59
背景:胆石性肠梗阻是胆石症的罕见并发症,是一种不常见的肠梗阻原因,占机械性肠梗阻的1%-4%。这通常是由一个或多个胆结石的腔内阻塞引起的。病例介绍:86岁男性,胆汁性呕吐15天,腹胀8天,诊断为胆结石性肠梗阻。手术治疗先开腹,再开肠,并从回肠近端取出胆结石。结论:机械性肠梗阻的早期诊断和治疗是重要的,否则会导致不良的预后。上海医科大学医学院;月,(2);2022年7月;页面57-59
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引用次数: 0
Monkeypox : A Global Health Emergency 猴痘:全球卫生紧急事件
Pub Date : 2022-12-08 DOI: 10.3329/cmoshmcj.v21i2.53598
R. Biswas, Md Jalal Uddin
Abstract not available Chatt Maa Shi Hosp Med Coll J; Vol.21 (2); July 2022; Page 1-2
[摘要]上海医科大学医学院;月,(2);2022年7月;1 - 2页
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引用次数: 0
Efficacy and Safety of Tranexamic Acid in Preventing Rebleeding after Subarachnoid Hemorrhage: A Randomized Controlled Trial 氨甲环酸预防蛛网膜下腔出血后再出血的有效性和安全性:一项随机对照试验
Pub Date : 2022-12-08 DOI: 10.3329/cmoshmcj.v21i2.63124
P. Das, Ashok Kumar Phani, Somen Chowdhury, Shemanta Waddadar, A. M. K. Chowdhury, Mohammad Shamchul Alam, Md Hosna Sadat Patwary, Shuva Das, Shiuly Majumdar, Md Hassanuzzaman
Background: Recent studies have indicated that early, short-course therapy with Tranexamic Acid (TXA) along with standard treatment for prevention of ischemia in aneurysmal Subarachnoid Hemorrhage (SAH) may be beneficial in preventing rebleeding and improving outcome. The study aimed to assess the efficacy and safety of short-course early administration of TXA combined with standard treatment to prevent rebleeding after SAH. Materials and methods: Seventy-four patients suffering from SAH verified on Computed Tomography (CT) scan within 72 hours after the primary hemorrhage were randomized into two treatment arms [37 received TXA and standard treatment (Experimental group), 37 received standard treatments only (Control group)]. TXA 1 gm was given intravenously slowly over 10 minutes, followed by 1 gm iv eight hourly up to a maximum of 72 hours. They were followed up for one month to observe rebleeding and outcome by Glasgow Outcome Scale. Results: Effective sample size was 70 (35 in TXA, 35 in the no-TXA group) due to the dropout of 4 patients. Out of 70 patients, 21 (30%) had rebleeding, and most of the rebleeding (95.23%) occurred after 72 hours of the initial event. Patients who had rebleeding had comparably lower GCS scores at presentation. Out of 21 rebleeding cases, 20 (95.23%) died within one month from the symptom onset. There was no significant difference (p=0.434) in rebleeding rate in TXA-treated patients (25.7%) versus non-TXA patients (34.3%). Treatment with TXA had no beneficial effect on one-month outcome (p>0.05).The adverse events were similar in the two groups and none of the patients had a seizure. Conclusions: Early short course TXA was tolerable as add-on to standard treatment of SAH but had no significant beneficial effect in reducing rebleeding and in improving one-month outcome. Chatt Maa Shi Hosp Med Coll J; Vol.21 (2); July 2022; Page 25-29 
背景:最近的研究表明,早期、短期应用氨甲环酸(TXA)联合标准治疗预防动脉瘤性蛛网膜下腔出血(SAH)缺血可能有助于预防再出血和改善预后。该研究旨在评估短期早期给药TXA联合标准治疗预防SAH后再出血的有效性和安全性。材料与方法:74例原发性出血后72小时内经CT扫描证实的SAH患者随机分为两组[37例接受TXA和标准治疗(实验组),37例仅接受标准治疗(对照组)]。TXA 1 gm在10分钟内缓慢静脉滴注,随后每8小时1 gm静脉滴注,最长72小时。随访1个月,观察再出血情况及格拉斯哥预后评分。结果:由于4例患者退出,有效样本量为70例(TXA组35例,无TXA组35例)。70例患者中有21例(30%)发生再出血,大多数再出血(95.23%)发生在初始事件72小时后。再出血患者就诊时GCS评分相对较低。21例再出血患者中,20例(95.23%)在症状出现后1个月内死亡。txa治疗组再出血率(25.7%)与非txa治疗组再出血率(34.3%)无显著差异(p=0.434)。TXA治疗对1个月预后无显著影响(p>0.05)。两组患者的不良事件相似,均未发生癫痫发作。结论:早期短期TXA作为SAH标准治疗的补充是可耐受的,但在减少再出血和改善一个月预后方面没有显著的有益作用。上海医科大学医学院;月,(2);2022年7月;25 - 29页
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引用次数: 0
Arousal Time from Sedation during Spinal Anaesthesia Given with Propofol and Midazolam for Elective Infraumbilical Surgeries 异丙酚和咪达唑仑脊髓麻醉用于选择性脐下手术时的镇静唤醒时间
Pub Date : 2022-12-08 DOI: 10.3329/cmoshmcj.v21i2.63089
Purabi Bardhan, M. Mannan, A. Malik, Sreekanta Chandra Banik
Background: Arousal time is variable after sedation with spinal anesthesia after infraumbilical surgeries. Propofol and midazolam have been studied individually using the Observer’s Assessment of Awareness/Sedation (OAA/S) score and different other ways. So this present study was designed to compare the arousal time of sedation for propofol and midazolam using OAA/S scores. Materials and methods: A total of 60 patients were randomly assigned to receive either propofol (Group A, n =30) or midazolam (Group B, n = 30). All patients of Group A received bolus of propofol (1 mg/kg) followed by infusion at 3 mg/kg/h, Group B received bolus of midazolam (0.05 mg/kg), followed by infusion at 0.06 mg/kg/h. OAA/S score was noted at beginning and again during recovery. The time to achieve OAA/S score 5 was noted. Changes of pulse rate, O2 saturation and satisfaction score were noted. Results: Among the 60 patients gender distributions where male and female distributed evenly. Age group distributions revealed more patients were gathered in age group 31- 40 years and >51 years. Regarding physical status most of the patients were at ASA physical status 1. It was found that propofol had better outcome than midazolam in terms of arousal time score and patient’s satisfaction score after surgery. Conclusions: A shorter arousal time from sedation during spinal anaesthesia can be achieved using propofol than arousal time with midazolam. Chatt Maa Shi Hosp Med Coll J; Vol.21 (2); July 2022; Page 18-21
背景:脐下手术后脊髓麻醉镇静后的觉醒时间是可变的。异丙酚和咪达唑仑分别使用观察者清醒/镇静评估(OAA/S)评分和不同的其他方法进行了研究。因此,本研究采用OAA/S评分比较异丙酚和咪达唑仑镇静唤醒时间。材料与方法:60例患者随机分为丙泊酚组(A组,n =30)和咪达唑仑组(B组,n =30)。A组患者给予异丙酚1 mg/kg,以3 mg/kg/h滴注;B组患者给予咪达唑仑0.05 mg/kg,以0.06 mg/kg/h滴注。在开始和恢复期间再次记录OAA/S评分。记录了达到OAA/S 5分的时间。观察脉搏率、血氧饱和度及满意度评分的变化。结果:60例患者性别分布中,男女分布均匀。年龄分布显示31 ~ 40岁和>51岁患者较多。在身体状态方面,大多数患者的身体状态为ASA 1。结果发现异丙酚在唤醒时间评分和术后患者满意度评分方面优于咪达唑仑。结论:与咪达唑仑相比,丙泊酚能缩短脊髓麻醉中镇静的唤醒时间。上海医科大学医学院;月,(2);2022年7月;第18 - 21页
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引用次数: 0
Serum D-Dimer in Lacunar Stroke 腔隙性脑卒中的血清d -二聚体
Pub Date : 2022-12-08 DOI: 10.3329/cmoshmcj.v21i2.63125
Muhammad Fakhrul Islam, M. N. Uddin, Md. Titu Miah
Background: Stroke is the third most common cause of death in the developed world as well as is the most common cause of severe physical disability. A good number of studies have shown elevated serum D-Dimer level in acute ischemic stroke. Approximately one quarter of ischemic strokes are caused by lacunar infarct. This study demonstrated serum D-Dimer in Lacunar Stroke. The purpose of the study to find out serum D-Dimer in Lacunar Stroke. Materials and methods: This cross-sectional study was conducted in Medicine Department, Dhaka Medical College, Dhaka on the patients with diagnosis of first ever acute lacunar Ischemic (LACI) stroke presented within 2 days of onset of symptoms. In this study, total 45 acute LACI cases irrespective of their gender were included and examined in presence of consultant physician, who were admitted from March 2014 to September 2014. Results: An overall male predominance with a male to female ratio was 2:1 with the mean (SD) age of the study population of lacunar stroke was 57.60 (12.68) years. At the distribution of common risk factors in this study, there were hypertension (n=26, 57%), smoking (n=18, 40%) Diabetes mellitus (n=14, 31.1%), dyslipidemia (n=12, 26.6%) and ischemic heart disease (n=9, 20. %). Accounting the focus point of our study, the mean (SD) value of serum D-Dimer was 0.37 (0.20) mg/L with gender difference in male and female [0.39 (0.20) mg/L Vs. 0.31 (0.19) mg/L]. A regression analysis was done to find the association of D-Dimer category group (Dependent variable) which were categorized as Normal range [D-Dimer level <0.5 mg/L (n=29)] and Increased level [D-Dimer level ³0.5 mg/L (n=16)] according to normal cutoff point of D-Dimer (<0.5 mg/L). It shows there was no statistically significant difference among normal and raised D-Dimer with gender, age, smoking, Tobacco, family history of CVD, hypertension, Diabetes mellitus, and dyslipidemia (p value > 0.05). But here, male and dyslipidemia patients were respectively 3.23 and 3.84 times more prone to develop increased level of D-Dimer, but it was statistically nonsignificant. Conclusion: In this study, it was found that serum D-Dimer was not significantly raised with Lacunar stoke patients. Though lacunar stroke is diagnosed specially by imaging methods, serum D-Dimer may play a role in diagnosis process to exclude from non-lacunar stoke. Chatt Maa Shi Hosp Med Coll J; Vol.21 (2); July 2022; Page 30-34
背景:中风是发达国家第三大常见死亡原因,也是造成严重身体残疾的最常见原因。大量研究表明急性缺血性脑卒中患者血清d -二聚体水平升高。大约四分之一的缺血性中风是由腔隙性梗死引起的。本研究证实了血清d -二聚体在腔隙性卒中中的作用。目的探讨腔隙性脑卒中患者血清d -二聚体的变化。材料与方法:本横断面研究在达卡医学院医学系对首次诊断为急性腔隙性缺血性中风(LACI)的患者在发病2天内进行。本研究纳入了2014年3月至2014年9月收治的45例急性LACI患者,不论其性别,均在咨询医师的陪同下进行检查。结果:腔隙性脑卒中研究人群总体以男性为主,男女比例为2:1,平均(SD)年龄为57.60(12.68)岁。在本研究的常见危险因素分布中,高血压(n=26, 57%)、吸烟(n=18, 40%)、糖尿病(n=14, 31.1%)、血脂异常(n=12, 26.6%)、缺血性心脏病(n=9, 20)。%)。作为我们研究的重点,血清d -二聚体的SD均值为0.37 (0.20)mg/L,男女差异明显[0.39 (0.20)mg/L Vs. 0.31 (0.19) mg/L]。回归分析d -二聚体类别组(因变量)与正常范围的相关性[d -二聚体水平0.05]。但在这里,男性和血脂异常患者d -二聚体水平升高的可能性分别是3.23倍和3.84倍,但无统计学意义。结论:本研究发现腔隙性卒中患者血清d -二聚体无明显升高。虽然腔隙性脑卒中是专门通过影像学诊断的,但血清d -二聚体可能在诊断过程中起到排除非腔隙性脑卒中的作用。上海医科大学医学院;月,(2);2022年7月;34页
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引用次数: 0
Evaluation of the Weightage on Pain Management in Pharmacology Curricula of MBBS Course in Bangladesh 孟加拉国MBBS课程药理学课程疼痛管理权重评价
Pub Date : 2022-12-08 DOI: 10.3329/cmoshmcj.v21i2.63129
J. Ferdoush, F. Johora, F. Jeenia, Tashfia Momtaz Chowdhury, H. Sadia, Rafana Arifina, A. Abbasy, M. Rahman
Background: Prioritizing problem-oriented undergraduate medical education is paramount to adequate management of pain in real life scenarios. The present research was conducted with an attempt to explore the important baseline information for pain medicine education and evaluation within pharmacology curricula of MBBS course in Bangladesh. Materials and methods: This descriptive cross-sectional study evaluates the curriculum (Pharmacology of MBBS curriculum, 2012), and written question (SAQ) of MBBS Examination of last ten years extending from January 2010 to November,2019 of all 7 universities offering MBBS degree. The evaluation was conducted through searching certain key phrases. Results: In Pharmacology and Therapeutics portion of the curriculum, only 4 hours and 2 hours are allocated to discuss pain management in lecture and tutorial respectively. In the study period, average marks allocated in pharmacology written question papers was 4.4 (SD ± 2.7) and the difference among studied universities was not significant (p value 0.7). Conclusion: Allocated time in the curricula to teach pain management is very low and weightage received in assessment is also inadequate. Education on pain medication as well as management should receive more emphasis. Chatt Maa Shi Hosp Med Coll J; Vol.21 (2); July 2022; Page 48-51
背景:优先考虑以问题为导向的本科医学教育对于在现实生活中充分管理疼痛至关重要。本研究旨在探讨孟加拉国MBBS课程药理学课程中疼痛医学教育和评估的重要基线信息。材料和方法:本描述性横断面研究评估了2010年1月至2019年11月,所有7所提供MBBS学位的大学近10年的MBBS课程(药理学课程,2012)和MBBS考试笔试(SAQ)。评价是通过搜索特定的关键词进行的。结果:在课程的药理学和治疗学部分,分别只有4学时和2学时的讲座和辅导课来讨论疼痛管理。在研究期间,药理学书面试卷的平均得分为4.4 (SD±2.7)分,在所研究的大学之间差异无统计学意义(p值0.7)。结论:疼痛管理课程的课时很少,评估的权重也不足。对疼痛药物和管理的教育应得到更多的重视。上海医科大学医学院;月,(2);2022年7月;页面48-51
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引用次数: 1
News & Views Vol. 21(2) 新闻与观点第21卷(2)
Pub Date : 2022-12-08 DOI: 10.3329/cmoshmcj.v21i2.63154
M. J. Uddin
Abstract not available Chatt Maa Shi Hosp Med Coll J; Vol.21 (2); July 2022; Page 67   
[摘要]上海医科大学医学院;月,(2);2022年7月;67页
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引用次数: 0
Comparison between Interrupted X Suture and Continuous Suture for Closure of Midline Incision in Emergency Laparotomy : A Randomized Controlled Trial 急诊剖腹切开中线切口间断缝合与连续缝合的比较:一项随机对照试验
Pub Date : 2022-12-08 DOI: 10.3329/cmoshmcj.v21i2.63130
Jasmin Begum, A. Ullah, Iftekharul Islam, Md. Al-Amin Chowdhury, Md. Abdullah Al Mansur, Utpak Kumar Das
Background: Wound dehiscence is disruption of any or all of the layers in a wound. At around 7–10 days post operatively leakage of clear sero-sanguinous fluid from the wound is usually the first indicator of burst abdomen. The patient usually feels something ‘giving away’ at this time.It may occur in 3-14.5% cases and is very distressing to the patient.Number of methods of closure of midline laparotomy wound have been introduced in the past to prevent this outcome. The study to compare the result of continuous and interrupted closure of midline emergency laparotomy in respect of burst abdomen. Materials and methods: This randomized controlled trial study was carried out in the Department of Surgery Chittagong Medical College Hospital, Chattogram, duration January 2017 to December 2017. A total of 500 patients were enrolled in this study. Data were collected, statistical analyses were obtained by using window based computer software devised with Statistical Packages for Social Sciences (SPSS-23). Results: 250 patients in group A and 250 in B. Surgical wound related post-operative complications were found in 30.4% of the study subjects (n=152).Wound dehiscence was found in 11% subjects, surgical site infection was found in 18.4% subjects and incisional hernia in 1%.All these complications were significantly higher in continuous suture group than interrupted group (p<0.001).Wound dehiscence in 20 subjects, treated with interrupted sutures and in 40 subjects (35 wound dehiscence and 5 incisional hernia)treated with continuous suture. The Relative Risk (RR) of developing wound dehiscence post-operatively was found to be 0.63 (95% CI 0.33 – 0.72) for interrupted suture. This was statistically significant (p<0.05). Conclusion: The interrupted X suture technique is better than continuous suture technique in prevention of burst abdomen in emergency midline laparotomy. Chatt Maa Shi Hosp Med Coll J; Vol.21 (2); July 2022; Page 52-56
背景:创面裂开是指创面任一层或全部层的破裂。术后7-10天左右,伤口有清晰的血清液渗出,通常是腹部破裂的第一个指标。这个时候病人通常会觉得有些东西“泄露”了。它可能发生在3-14.5%的病例中,对患者来说非常痛苦。为了防止这种结果,过去已经介绍了许多关闭剖腹开腹中线伤口的方法。本研究比较连续与间断中线急诊剖腹手术治疗腹壁破裂的效果。材料与方法:本随机对照试验研究于2017年1月至2017年12月在Chattogram吉大港医学院附属医院外科进行。共有500名患者参加了这项研究。采用SPSS-23 (statistical Packages for Social Sciences)软件进行数据收集和统计分析。结果:A组250例,b组250例,术后切口相关并发症发生率为30.4% (n=152)。伤口裂开占11%,手术部位感染占18.4%,切口疝占1%。这些并发症连续缝合组明显高于间断缝合组(p<0.001)。伤口裂开20例,采用间断缝合治疗;伤口裂开35例,切口疝5例,采用连续缝合治疗。中断缝合术后创面裂开的相对危险度(RR)为0.63 (95% CI 0.33 ~ 0.72)。差异有统计学意义(p<0.05)。结论:间断X线缝合技术在预防急诊剖腹切开术中腹裂的效果优于连续缝合技术。上海医科大学医学院;月,(2);2022年7月;页面52-56
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引用次数: 0
Pattern of Self-Reported Behavioural Risk Factors of Non-Communicable Diseases among Doctors Working in a Tertiary Care Hospital 三级医院医生自我报告非传染性疾病行为风险因素的模式
Pub Date : 2022-12-08 DOI: 10.3329/cmoshmcj.v21i2.63088
S. Sarkar, Raju Dey, B. Chowdhury, Shahryar Ahmed, Sagar Chowdhury
Background: Behavioural risk factors reduction is a key to Non-Communicable Diseases (NCDs) control. The doctors are educated and aware of society, yet their lifestyle and work habits have led them to suffer from NCDs. This study was carried out to determine the prevalence of the behavioral risk factors of major NCDs among doctors working at Chittagong Medical College Hospital (CMCH). Materials and methods: This cross-sectional study included 145 doctors working at CMCH from April 2020 to September 2020. A structured self-administered questionnaire based on the WHO STEPS instrument for NCDs risks factors surveys was used to collect data. Results: Out of 145 respondents, 104 doctors (71.7%) were males, and 41 doctors (28.3%) were females. Most doctors (50.3%) were aged 23 to 35 years and 29.7% were 35-44 years. The proportion of doctors currently smoking tobacco, drinking alcohol, being sedentary in daily life, and taking low vegetables and fruits was 8.3%, 8.3%, 18.6%, and 72.4%, respectively. No female doctor reported smoking or drinking. Ninety-one (62.8%) of doctors had one risk habit and 17.2% with two risk habits. Conclusion: It is desirable that doctors voluntarily strive to have a favourable lifestyle and that medical institutions actively enlighten doctors’ working at their institutions about this issue. Chatt Maa Shi Hosp Med Coll J; Vol.21 (2); July 2022; Page 14-17
背景:减少行为风险因素是控制非传染性疾病的关键。医生受过教育,了解社会,但他们的生活方式和工作习惯使他们遭受非传染性疾病的折磨。本研究旨在确定吉大港医学院附属医院(CMCH)医生主要非传染性疾病行为危险因素的流行情况。材料与方法:本横断面研究纳入了2020年4月至2020年9月在CMCH工作的145名医生。采用基于世卫组织STEPS非传染性疾病风险因素调查工具的结构化自我管理问卷收集数据。结果:145名受访医生中,男性104名(71.7%),女性41名(28.3%)。23 ~ 35岁占50.3%,35 ~ 44岁占29.7%。目前吸烟、饮酒、日常久坐、少吃蔬菜水果的比例分别为8.3%、8.3%、18.6%和72.4%。没有女医生报告吸烟或饮酒。91名医生(62.8%)有一种危险习惯,17.2%有两种危险习惯。结论:医生应主动努力养成良好的生活方式,医疗机构应积极对在本机构工作的医生进行这方面的教育。上海医科大学医学院;月,(2);2022年7月;14 - 17页
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引用次数: 0
Diagnostic Accuracy of Urinary Reagent Strip to Determine CSF Chemistry and Cellularity 尿试剂条测定脑脊液化学和细胞组成的诊断准确性
Pub Date : 2022-12-08 DOI: 10.3329/cmoshmcj.v21i2.63087
Shemanta Waddadar, A. M. K. Chowdhury, Rajsree Chowdhury, P. Das, Mohammad Shamchul Alam, M. Rubel, S. Majumder, M. Hassanuzzaman
Background: Cerebrospinal Fluid (CSF) examination is a common investigation to diagnose and evaluate different neurological diseases. The gold standard method of CSF examination is microscopy, biochemistry and culture in a standard laboratory, which require an experienced microscopist and laboratory support. Urinary reagent strip can be a point of care test in such condition. The study aimed to document the diagnostic accuracy of urinary reagent strip for the semi-quantitative analysis of CSF chemistry and cellularity. Materials and methods: One hundred hospitalized patients from the Department of Neurology, Chittagong Medical College Hospital were included in this study. CSF samples of the patients were subjected for the de nitive test (CSF microscopy and laboratory biochemical values) and the index test [Combur-10 urinary reagent strip was used as the index test for protein, glucose, leukocytes and erythrocytes. The diagnostic accuracy of each index test was calculated using different cut-off levels (Glucose 1+ vs. CSF glucose >50 mg/dL, protein 1+ vs. CSF protein >30 mg/dL, leukocyte esterase 1+ positivity vs. >10 granulocytes/mm3 and erythrocyte 1+ positivity versus >5 RBC/mm3 in CSF sample). Results: The diagnostic accuracy of protein estimation by reagent strip shows 100% sensitivity, 84.21% specificity for detection of CSF protein at level 30mg/dl. Glucose reagent strip positivity had 98.8% sensitivity and 75% specificity for detection of CSF glucose at level 50 mg/dl. Leukocyte esterase positivity by test strip had sensitivity of 60% and specificity of 100% for the detection of CSF granulocyte of >10 granulocytes/mm3. The diagnostic accuracy of erythrocyte estimation by reagent strip show 92% sensitivity, 92% specificity for detection of CSF RBC >5 cells/mm3. Conclusion: Urinary reagent strip can be used routinely for rapid analysis of CSF.A resource-limited hospital might find it useful as a point-of-care laboratory workup of CSF. Chatt Maa Shi Hosp Med Coll J; Vol.21 (2); July 2022; Page 9-13
背景:脑脊液检查是诊断和评价不同神经系统疾病的常用检查方法。脑脊液检查的金标准方法是显微镜、生物化学和标准实验室培养,这需要有经验的显微镜师和实验室支持。在这种情况下,尿试剂条可以作为检查点。本研究旨在证明尿试剂条用于脑脊液化学和细胞结构半定量分析的诊断准确性。材料与方法:选取吉大港医学院附属医院神经内科住院患者100例。对患者脑脊液标本进行定性试验(脑脊液镜检及实验室生化值),以Combur-10尿试剂试纸作为蛋白质、葡萄糖、白细胞、红细胞的指标试验。使用不同的临界值(脑脊液样品中葡萄糖1+ vs脑脊液葡萄糖>50 mg/dL,蛋白1+ vs脑脊液蛋白>30 mg/dL,白细胞酯酶1+阳性vs脑脊液中>0个粒细胞/mm3,红细胞1+阳性vs脑脊液中bbb5个红细胞/mm3)计算各项指标测试的诊断准确性。结果:试剂条法检测脑脊液蛋白在30mg/dl水平时灵敏度为100%,特异性为84.21%。葡萄糖试剂条阳性检测50 mg/dl时脑脊液葡萄糖的敏感性为98.8%,特异性为75%。白细胞酯酶试纸阳性检测脑脊液粒细胞bbb10 /mm3的灵敏度为60%,特异性为100%。试剂条法测定红细胞的诊断准确率为:敏感性92%,特异性92%,检测脑脊液红细胞bbb50个/mm3。结论:尿试剂条可常规用于脑脊液的快速分析。资源有限的医院可能会发现它作为脑脊液的即时实验室检查很有用。上海医科大学医学院;月,(2);2022年7月;第四页
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引用次数: 0
期刊
Chattagram Maa-O-Shishu Hospital Medical College Journal
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