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Socio-demographic and other factors contributing to excessive leisure screen time in preadolescent children. 导致青春期前儿童休闲屏幕时间过长的社会人口因素和其他因素。
IF 1.1 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-09-01 DOI: 10.21101/cejph.a7941
Kateřina Lukavská, Michal Božík, Niko Männikkö, Ondřej Hrabec, Michaela Slussareff, Jaroslav Vacek, Martina Píšová, Roman Gabrhelík

Objectives: Excessive screen use in early school age is associated with worsened health habits and negative child development in later age. We aimed to assess the time spent on modern and traditional screen-based devices and examine its associations with socio-demographic characteristics.

Methods: This population-based cross-sectional observation study was conducted in Czechia, Slovakia and Finland between April and June 2021. Participants (N = 1,915) were parents/caregivers of children attending elementary school grades 1 to 3, selected by stratified random sampling. Children's daily leisure screen time (LST) based on parental reports was the main outcome. Descriptive statistics, mean comparison and linear regression analysis were used for the analysis.

Results: The average daily LST was found to be as high as 3.5 hours and significantly associated with most socio-demographic variables. Eighty percent of children exceeded the threshold of two hours of LST per day, which was formerly introduced by the American Academy of Pediatrics. The most important predictor of LST in children was having their screen-based device(s) for their exclusive personal use (EPU). Linear regression with all predictors assessed together confirmed the significant effect of the screen-based devices' EPU, the child's sex and grade, the child's birth order and the parent's education, even when controlled for media parenting practices.

Conclusions: Given the widespread availability of smartphones for exclusive personal use among young children, the regulation of EPU and the reinforcement of effective media parenting practices, particularly in families with lower education and income, are critical public health strategies to mitigate the negative impact of excessive screen time on child development and overall well-being.

目的:学龄早期过度使用屏幕与健康习惯恶化和儿童日后的不良发展有关。我们旨在评估使用现代和传统屏幕设备的时间,并研究其与社会人口特征的关系:这项基于人口的横断面观察研究于 2021 年 4 月至 6 月间在捷克、斯洛伐克和芬兰进行。参与者(N = 1,915)是通过分层随机抽样选出的小学一至三年级儿童的父母/监护人。主要结果是根据家长报告的儿童每日休闲屏幕时间(LST)。分析采用了描述性统计、均值比较和线性回归分析等方法:结果发现,儿童的日均闲暇屏幕时间高达 3.5 小时,且与大多数社会人口变量有显著关联。80%的儿童都超过了美国儿科学会以前规定的每天两小时的LST阈值。预测儿童长时间使用电脑的最重要因素是他们的个人专用屏幕设备(EPU)。将所有预测因素一并评估的线性回归结果证实,即使在控制了媒体养育实践的情况下,屏幕设备的个人专用程度、儿童的性别和年级、儿童的出生顺序以及父母的教育程度也有显著影响:结论:鉴于智能手机在幼儿中广泛普及,供个人专用,因此,尤其是在教育程度和收入较低的家庭中,规范电子屏幕使用时间和加强有效的媒体养育方法是减轻过度使用屏幕时间对儿童发育和整体健康的负面影响的重要公共卫生策略。
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引用次数: 0
Course and complications of influenza A in seniors over 65 years of age. 65 岁以上老年人甲型流感的病程和并发症。
IF 1.1 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-09-01 DOI: 10.21101/cejph.a7877
Dalibor Sedláček, Robin Šín, Patrik Christian Cmorej, Miroslav Kubiska

Objectives: Influenza A and B viruses cause epidemics every year, with approximately 3-5 million serious cases and about 290,000 to 650,000 deaths worldwide. Most patients die from bacterial complications of influenza. The aim of our study was to describe the clinical pictures of influenza and the development of the complications in seniors over 65 years of age, who were treated in University Hospital Pilsen. The course of the disease and changes in laboratory parameters were evaluated with regard to the method of treatment performed.

Methods: A descriptive retrospective study was performed. Clinical and laboratory data of seniors with the diagnosis of influenza were extracted from electronic medical records and later analysed. The data were processed with Excel 2016 and Statistica.

Results: A collection of 261 seniors, of whom 218 were hospitalized and 43 treated in an outpatient setting, has been studied. Patients who later developed complications had elevated values of CRP, procalcitonin, urea, and creatinine. The antiviral drug oseltamivir was administered to 226 of 261 seniors. Forty-seven seniors (18.0%) died from influenza and its complications (severe pneumonia with acute respiratory insufficiency or heart failure).

Conclusions: The course of influenza in seniors was usually more severe and required hospitalization along with antiviral treatment. The mortality rate in the monitored group exceeded 18%. Annual timely vaccination, but also other preventive measures, and maybe considering other risk groups are methods to prevent severe or even fatal cases of influenza.

目的:甲型和乙型流感病毒每年都会引发流行病,全球约有 300-500 万例严重病例,约 29 万至 65 万人死亡。大多数患者死于流感的细菌并发症。我们的研究旨在描述在比尔森大学医院接受治疗的 65 岁以上老年人的流感临床表现和并发症发展情况。我们还根据所采用的治疗方法评估了病程和实验室参数的变化:方法:进行了一项描述性回顾研究。研究人员从电子病历中提取了确诊为流感的老年人的临床和实验室数据,随后进行了分析。数据使用 Excel 2016 和 Statistica 进行处理:研究对象包括 261 名老年人,其中 218 人住院治疗,43 人在门诊接受治疗。后来出现并发症的患者的 CRP、降钙素原、尿素和肌酐值升高。261 名老年人中有 226 人服用了抗病毒药物奥司他韦。47名老年人(18.0%)死于流感及其并发症(重症肺炎伴急性呼吸功能不全或心力衰竭):结论:老年人的流感病程通常更为严重,需要住院治疗和抗病毒治疗。监测组的死亡率超过 18%。每年及时接种疫苗,同时采取其他预防措施,并考虑其他高危人群,是预防严重甚至致命流感病例的方法。
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引用次数: 0
Mediterranean diet adherence in 9-years old children: a cross-sectional study in the part of the Split-Dalmatia County, Croatia. 克罗地亚斯普利特-达尔马提亚县部分地区 9 岁儿童的地中海饮食习惯:横断面研究。
IF 1.1 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-09-01 DOI: 10.21101/cejph.a8094
Katarina Tomelić Ercegović, Petar Đolonga, Zvonimir Družianić, Vladimir Ercegović, Željka Karin

Objectives: Childhood obesity is a growing global problem that can be prevented by improving diet quality. Mediterranean diet (MedDiet), historically present in Mediterranean countries, is considered one of the healthiest dietary patterns. This cross-sectional study aimed to determine the MedDiet adherence and anthropometric parameters in 9-year-old children from the central geographic locations of Split-Dalmatia County, Croatia.

Methods: The study analysed data obtained from 158 children aged nine years from central parts of Dalmatia: Split and Hvar. To assess the MedDiet adherence, the parents of the children filled out the Mediterranean Diet Index (KIDMED) questionnaire. Appointed school medicine specialists collected anthropometric data of the children and categorized them into body mass index (BMI) categories according to the Center for Disease Control and Prevention (CDC) criteria. Additionally, we assessed the influence of parents' education degree on children's MedDiet adherence and anthropometric measures.

Results: Results showed that more than a quarter of nine-year-olds included in this study were overweight or obese (BMI ≥ 85th percentile for age and sex). One of the main findings was that 72% of children had suboptimal (poor or average) MedDiet adherence. Moreover, children with suboptimal KIDMED results (KI < 8) had significantly higher body weight, waist circumference, hip circumference, and waist-to-height ratio. Also, results showed that mothers' education notably influences children's anthropometry.

Conclusion: Our study found that childhood obesity is a significant concern among 9-year-olds, with a high prevalence of overweight and obesity. Additionally, our results showed that MedDiet adherence is suboptimal among this age group. These results indicate that children of the Mediterranean are not spared of modern life challenges. This problem should be prioritized in the future to prevent the development of a metabolically compromised adult population.

目标:儿童肥胖症是一个日益严重的全球性问题,可以通过改善饮食质量来预防。地中海饮食(MedDiet)历来存在于地中海国家,被认为是最健康的饮食模式之一。这项横断面研究旨在确定克罗地亚斯普利特-达尔马提亚县中部地区 9 岁儿童的地中海饮食坚持情况和人体测量参数:研究分析了来自达尔马提亚中部地区 158 名 9 岁儿童的数据:斯普利特和赫瓦尔。为了评估地中海饮食坚持情况,儿童的父母填写了地中海饮食指数(KIDMED)问卷。学校指定的医学专家收集了儿童的人体测量数据,并根据美国疾病控制和预防中心(CDC)的标准将他们划分为体重指数(BMI)类别。此外,我们还评估了父母的受教育程度对儿童坚持 "健康饮食 "和人体测量的影响:结果:研究结果显示,超过四分之一的九岁儿童超重或肥胖(体重指数≥年龄和性别百分位数的 85)。研究的主要发现之一是,72%的儿童对 "健康饮食 "的依从性不达标(较差或一般)。此外,KIDMED结果不达标(KI<8)的儿童体重、腰围、臀围和腰围身高比明显偏高。研究结果还显示,母亲的受教育程度对儿童的人体测量有明显影响:我们的研究发现,儿童肥胖症是 9 岁儿童中的一个重大问题,超重和肥胖的发生率很高。此外,我们的研究结果表明,该年龄段儿童的 "地中海饮食 "坚持率并不理想。这些结果表明,地中海地区的儿童也不能幸免于现代生活的挑战。今后应优先考虑这一问题,以防止出现代谢受损的成年人口。
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引用次数: 0
Not bitten by Ixodes ticks or bitten without symptoms, why still to worry? 没有被蜱虫叮咬或被叮咬后没有症状,为什么还要担心?
IF 1.1 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-09-01 DOI: 10.21101/cejph.a8114
Mykhaylo Andreychyn, Maria Shkilna, Oleksandr Tokarskyy, Oleh Ivakhiv, Zoriana Smahlii, Mykhaylo Korda

Objectives: The purpose of the current study was to analyse the risks of Lyme borreliosis (LB) among 1,070 forestry workers, the influence of responsible behaviour (use of repellents, skin self-inspection) on Borrelia screening result status, and the occurrence of immediate and mid-term symptoms after tick bites and LB positive serological screening test.

Methods: The questionnaire was conducted as well as blood tests for LB disease by one-stage serological screening procedure using ELISA for specific B. burgdorferi IgM and IgG antibodies (EuroImmun AG company, Germany).

Results: While 39.6% of foresters were LB positive among bitten foresters, as many as 27.0% were LB positive among those, who did not recall any tick attacks at all. Individuals with known history of tick bites had significantly higher odds (1.770×) of being LB positive (p < 0.05), while the use of repellents or skin self-inspection after visiting woods had no influence on LB results. The odds of skin discolouration after tick bites was significantly lower (0.682×) in case of LB positive test compared to LB negative test (p < 0.05), which can be explained by the fact that foresters could be unaware about erythema migrans appearance and timing, considering tick bite and developed later rash as completely separate events. Moreover, 69.1% of the bitten foresters with LB positive result developed no secondary symptoms (excluding those related to the skin), and the most frequent clinical symptoms were arthralgia (24.9%), followed by myalgia (7.6%), headache (5.7%), and damage to facial nerve (2.7%), which are non-specific and can be present in other illnesses.

Conclusion: Therefore, the recommendations proposed would be the regular laboratory testing for LB of sensitive and at-risk population, who visits endemic woody areas, irrespective of all other factors involved.

研究目的本研究的目的是分析 1070 名林业工人患莱姆包虫病(LB)的风险、负责任的行为(使用驱虫剂、皮肤自我检查)对包虫病筛查结果状况的影响,以及蜱虫叮咬和 LB 血清学筛查试验阳性后出现的近期和中期症状:方法:在进行问卷调查的同时,还通过使用 ELISA 检测特异性 B. burgdorferi IgM 和 IgG 抗体(德国 EuroImmun AG 公司)的单阶段血清学筛查程序对结核病进行血液检测:结果:在被咬伤的林业人员中,有 39.6% 的人乙型肝炎抗体呈阳性,而在完全不记得有蜱虫叮咬的人中,乙型肝炎抗体呈阳性的人高达 27.0%。已知有蜱虫叮咬史的人出现枸杞多糖阳性的几率明显更高(1.770×)(p < 0.05),而使用驱避剂或在游览树林后进行皮肤自我检查对枸杞多糖阳性结果没有影响。蜱虫叮咬后皮肤变色的几率(0.682×)在枸橼酸试验阳性的情况下明显低于枸橼酸试验阴性的情况(p < 0.05),这可能是由于林业人员可能不了解迁徙性红斑的出现和时间,认为蜱虫叮咬和后来出现的皮疹是完全独立的事件。此外,在 LB 阳性的被咬林农中,69.1% 没有出现继发症状(不包括与皮肤有关的症状),最常见的临床症状是关节痛(24.9%),其次是肌痛(7.6%)、头痛(5.7%)和面部神经损伤(2.7%),这些症状都是非特异性的,也可能出现在其他疾病中:因此,建议对前往林木流行区的敏感人群和高危人群定期进行结核病实验室检测,而不考虑所有其他因素。
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引用次数: 0
Role of diet in development of non-communicable diseases: focus on gut microbiome. 饮食在非传染性疾病发展中的作用:关注肠道微生物组。
IF 1.1 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-09-01 DOI: 10.21101/cejph.a8138
Andrea Fričová, Anna Zavaďáková, Monika Bludovská

Objectives: The dietary composition is able to rapidly and significantly influence the diversity of the gut microbiome. This article focuses on how various types of diet affect the composition of the gut microbiome and how dietary changes are able to prevent or slow down the development of non-communicable diseases including obesity, type 2 diabetes mellitus, cardiovascular diseases, and low-grade inflammation.

Methods: A review in PubMed and a hand search using references in identified articles were performed. Studies published in English from 2000 to 2024 were included.

Results: The studies showed the significant effect of diet on the development of non-communicable diseases dependent on the state of the gut microbiota and molecules it produces. The Western diet that continues to gain in popularity for Czech people, leads to dysbiosis and production of bacterial lipopolysaccharide or trimethylamine N-oxide causing systemic chronic inflammation in the body and thus promoting the development of non-communicable diseases.

Conclusions: Findings from this review emphasize the importance of healthy eating habits in the prevention of intestinal dysbiosis and still increasing prevalence and incidence of obesity and other non-communicable diseases.

目的:膳食结构能够快速、显著地影响肠道微生物组的多样性。本文重点探讨各种类型的饮食如何影响肠道微生物组的组成,以及饮食改变如何预防或减缓非传染性疾病(包括肥胖、2 型糖尿病、心血管疾病和低度炎症)的发生:方法:在 PubMed 上进行了综述,并利用已确定文章中的参考文献进行了人工搜索。结果:研究表明,饮食对糖尿病、心血管疾病和低度炎症有显著影响:研究结果表明,饮食对非传染性疾病的发生有重大影响,这取决于肠道微生物群的状态及其产生的分子。捷克人越来越喜欢的西式饮食会导致菌群失调,产生细菌脂多糖或三甲胺 N-氧化物,引起全身慢性炎症,从而促进非传染性疾病的发展:本综述的研究结果强调了健康饮食习惯在预防肠道菌群失调以及肥胖和其他非传染性疾病的流行率和发病率不断上升方面的重要性。
{"title":"Role of diet in development of non-communicable diseases: focus on gut microbiome.","authors":"Andrea Fričová, Anna Zavaďáková, Monika Bludovská","doi":"10.21101/cejph.a8138","DOIUrl":"https://doi.org/10.21101/cejph.a8138","url":null,"abstract":"<p><strong>Objectives: </strong>The dietary composition is able to rapidly and significantly influence the diversity of the gut microbiome. This article focuses on how various types of diet affect the composition of the gut microbiome and how dietary changes are able to prevent or slow down the development of non-communicable diseases including obesity, type 2 diabetes mellitus, cardiovascular diseases, and low-grade inflammation.</p><p><strong>Methods: </strong>A review in PubMed and a hand search using references in identified articles were performed. Studies published in English from 2000 to 2024 were included.</p><p><strong>Results: </strong>The studies showed the significant effect of diet on the development of non-communicable diseases dependent on the state of the gut microbiota and molecules it produces. The Western diet that continues to gain in popularity for Czech people, leads to dysbiosis and production of bacterial lipopolysaccharide or trimethylamine N-oxide causing systemic chronic inflammation in the body and thus promoting the development of non-communicable diseases.</p><p><strong>Conclusions: </strong>Findings from this review emphasize the importance of healthy eating habits in the prevention of intestinal dysbiosis and still increasing prevalence and incidence of obesity and other non-communicable diseases.</p>","PeriodicalId":9823,"journal":{"name":"Central European journal of public health","volume":"32 3","pages":"200-204"},"PeriodicalIF":1.1,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142342601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A post-pandemic trend in the consumption of dietary supplements among residents of Lithuania. 立陶宛居民膳食补充剂消费的流行后趋势。
IF 1.1 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-09-01 DOI: 10.21101/cejph.a8092
Rokas Arlauskas, Donatas Austys, Rimantas Stukas

Objectives: The consumption of dietary supplements might prevent the deficiency of necessary nutrients. On the other hand, in cases of overconsumption, adverse effects might occur. In Lithuania, the COVID-19 pandemic provoked an increase in the consumption of dietary supplements. The aim of this study was to reveal the post-pandemic trend of the consumption of dietary supplements among the working-age residents of Lithuania with respect to social and demographic factors and food selection criteria.

Methods: A cross-sectional observational study was performed. In total, using the same methods, 3,200 residents were surveyed: 1,600 in 2021 and 1,600 in 2022. Both samples were representative for Lithuania and included residents of Lithuania aged from 18 to 64 years. According to socio-demographic factors (sex, age, level of education, type of place of residence, marital status, number of family members, presence of children under 18 years old in the household, employment status, level of income), COVID-19 experience (presence of COVID-19 cases among friends or relatives, severeness of COVID-19) and food selection criteria (health strengthening, other) the prevalence of the consumption of dietary supplements was compared between the samples.

Results: The consumption of dietary supplements accounted for 78.1% and 71.6% of the respondents in 2021 and 2022, respectively (p < 0.001). After the COVID-19 pandemic, the prevalence of the consumption of dietary supplements decreased in the majority of social and demographic groups analysed in this article (p < 0.05). The consumption of dietary supplements remained unchanged among those who selected foods for health strengthening (p = 0.098).

Conclusions: The prevalence of the consumption of dietary supplements decreased after the COVID-19 pandemic in most social and demographic groups except those who selected foods for health strengthening.

目的:食用膳食补充剂可防止缺乏必要的营养素。另一方面,在过度摄入的情况下,可能会产生不良影响。在立陶宛,COVID-19 大流行引发了膳食补充剂消费量的增加。本研究的目的是根据社会和人口因素以及食物选择标准,揭示立陶宛工作年龄居民在大流行后食用膳食补充剂的趋势:方法:进行横断面观察研究。采用相同的方法,共调查了 3200 名居民:其中 1600 人在 2021 年接受调查,1600 人在 2022 年接受调查。两个样本在立陶宛都具有代表性,包括 18 至 64 岁的立陶宛居民。根据社会人口因素(性别、年龄、教育水平、居住地类型、婚姻状况、家庭成员数量、家中是否有 18 岁以下儿童、就业状况、收入水平)、COVID-19 经验(亲友中是否有 COVID-19 病例、COVID-19 严重程度)和食物选择标准(加强健康、其他),比较了样本间膳食补充剂消费的普遍程度:结果:2021 年和 2022 年分别有 78.1%和 71.6%的受访者食用膳食补充剂(p < 0.001)。在 COVID-19 大流行后,本文分析的大多数社会和人口群体的膳食补充剂消费率都有所下降(p < 0.05)。在那些选择食品以增强健康的人群中,膳食补充剂的消费量保持不变(p = 0.098):结论:COVID-19 大流行后,除选择加强健康食品的人群外,大多数社会和人口群体的膳食补充剂消费率都有所下降。
{"title":"A post-pandemic trend in the consumption of dietary supplements among residents of Lithuania.","authors":"Rokas Arlauskas, Donatas Austys, Rimantas Stukas","doi":"10.21101/cejph.a8092","DOIUrl":"10.21101/cejph.a8092","url":null,"abstract":"<p><strong>Objectives: </strong>The consumption of dietary supplements might prevent the deficiency of necessary nutrients. On the other hand, in cases of overconsumption, adverse effects might occur. In Lithuania, the COVID-19 pandemic provoked an increase in the consumption of dietary supplements. The aim of this study was to reveal the post-pandemic trend of the consumption of dietary supplements among the working-age residents of Lithuania with respect to social and demographic factors and food selection criteria.</p><p><strong>Methods: </strong>A cross-sectional observational study was performed. In total, using the same methods, 3,200 residents were surveyed: 1,600 in 2021 and 1,600 in 2022. Both samples were representative for Lithuania and included residents of Lithuania aged from 18 to 64 years. According to socio-demographic factors (sex, age, level of education, type of place of residence, marital status, number of family members, presence of children under 18 years old in the household, employment status, level of income), COVID-19 experience (presence of COVID-19 cases among friends or relatives, severeness of COVID-19) and food selection criteria (health strengthening, other) the prevalence of the consumption of dietary supplements was compared between the samples.</p><p><strong>Results: </strong>The consumption of dietary supplements accounted for 78.1% and 71.6% of the respondents in 2021 and 2022, respectively (p < 0.001). After the COVID-19 pandemic, the prevalence of the consumption of dietary supplements decreased in the majority of social and demographic groups analysed in this article (p < 0.05). The consumption of dietary supplements remained unchanged among those who selected foods for health strengthening (p = 0.098).</p><p><strong>Conclusions: </strong>The prevalence of the consumption of dietary supplements decreased after the COVID-19 pandemic in most social and demographic groups except those who selected foods for health strengthening.</p>","PeriodicalId":9823,"journal":{"name":"Central European journal of public health","volume":"32 3","pages":"189-199"},"PeriodicalIF":1.1,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142342578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of climate on varicella distribution in Bulgaria (2009-2018). 气候对保加利亚水痘分布的影响(2009-2018 年)。
IF 1.1 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-09-01 DOI: 10.21101/cejph.a7792
Tatina Todorova

Objectives: Temperature is the most important environmental variable associated with the varicella frequency across the world. The present study compares the incidence of varicella in the districts of Bulgaria against some climatic factors and tries to find environmental variables which account for the differences in the varicella distribution observed among the Bulgarian districts.

Methods: The 28 Bulgarian districts were used as units of observation and their average 10-year varicella incidence (2009-2018) was tested for correlation with the standard bioclimatic variables of WorldClim, version 2.

Results: The WorldClim estimates for the annual mean temperature, the maximal temperature of the warmest month, the minimal temperature of the coldest month, the mean temperature of the coldest quarter, and the solar radiation inversely and not significantly correlated with the average 10-year varicella frequency. The precipitation of the warmest quarter and the wind speed correlated positively and also not significantly. Only the mean temperature of the driest quarter correlates significantly with the incidence at district level (Spearman's rank correlation coefficient of -0.45, p = 0.02). The mean of average 10-year varicella incidence rates among districts with driest quarter during the winter (January, February, March) was 387.6 ± 114.1, while among districts with driest quarter during the summer/autumn (July, August, September or August, September, October) 283.3 ± 102.1 (p = 0.02, ANOVA test).

Conclusions: Dry winter and/or wet summer appear as significant determinants for the fluctuant spread of varicella infection in Bulgaria.

目的:温度是与世界各地水痘发病率相关的最重要的环境变量。本研究将保加利亚各地区的水痘发病率与一些气候因素进行比较,并试图找到导致保加利亚各地区水痘分布差异的环境变量:方法:以保加利亚的 28 个地区为观察单位,测试其 10 年(2009-2018 年)水痘平均发病率与 WorldClim 第 2 版标准生物气候变量的相关性:WorldClim估计的年平均气温、最暖月份的最高气温、最冷月份的最低气温、最冷季度的平均气温和太阳辐射与10年平均水痘发病率成反比,且无显著相关性。最热季度的降水量和风速呈正相关,但也不显著。只有最干旱季度的平均气温与地区一级的发病率有明显相关性(斯皮尔曼等级相关系数为-0.45,p = 0.02)。冬季(1 月、2 月、3 月)最干燥季度的地区 10 年水痘平均发病率平均值为 387.6 ± 114.1,而夏季/秋季(7 月、8 月、9 月或 8 月、9 月、10 月)最干燥季度的地区为 283.3 ± 102.1(p = 0.02,方差分析检验):结论:干燥的冬季和/或潮湿的夏季似乎是保加利亚水痘感染波动传播的重要决定因素。
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引用次数: 0
Occupational respiratory disease in Eastern Slovakia between 1990-2021: a shift from agriculture to industrial manufacturing. 1990-2021 年间东斯洛伐克的职业呼吸道疾病:从农业向工业制造业的转变。
IF 1.1 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-09-01 DOI: 10.21101/cejph.a8111
Ľubomír Legáth, Ivan Tkáč, Petra Dittrichová, Ivan Perečinský, Miroslava Matejová, Slavomír Perečinský

Objectives: Occupational allergic respiratory diseases frequently occur in individuals working in the agricultural and food production sectors, textile manufacturing, and industries involving exposure to isocyanates. The study aimed to describe trends surrounding the prevalence of occupational asthma (OA), occupational rhinitis (OR), and occupational hypersensitivity pneumonitis (OHP) in Eastern Slovakia between 1990-2021.

Methods: All cases of OA, OR, and OHP registered in a database at the Louis Pasteur University Hospital in Košice, Slovakia, between 1990 and 2021, were divided into categories based on economic sector (agricultural, food production sectors, textile manufacturing, healthcare, industrial manufacturing, and tertiary sector) and causal agent. Changes in disease prevalence, causal agents, and economic sector association over time were analysed.

Results: There were 287 occupational respiratory cases (179 OA, 65 OR, and 43 OHP cases). The annual prevalence of OA declined significantly over the study period (p < 0.05). Overall, there was a significant decrease in cases from the agricultural (p < 0.001) and an increase in the industrial manufacturing (p < 0.01). The number of cases due to farming agents fell markedly over the study period, while metalworking fluids (MWFs) were found to be the most common causes of allergic respiratory diseases since 2018.

Conclusions: This study found a decrease in the number of OA cases, as well as changes in economic sectors and causal agents associated with OA and OHP, specifically, in the agricultural sector, with MWFs from the industrial manufacturing sector now being the most common aetiological agent.

目的:在农业和食品生产部门、纺织制造业以及接触异氰酸酯的行业工作的人经常会患上职业过敏性呼吸道疾病。本研究旨在描述 1990-2021 年间东斯洛伐克职业性哮喘(OA)、职业性鼻炎(OR)和职业性过敏性肺炎(OHP)的发病趋势:根据经济部门(农业、食品生产部门、纺织制造、医疗保健、工业制造和第三产业)和致病因素,将 1990 年至 2021 年期间斯洛伐克科希策路易-巴斯德大学医院数据库中登记的所有职业性哮喘、职业性鼻炎和职业性超敏性肺炎病例进行分类。结果分析了疾病流行率、致病因素和经济部门相关性随时间的变化:共有 287 例职业性呼吸道病例(179 例 OA、65 例 OR 和 43 例 OHP)。在研究期间,OA 的年发病率显著下降(p < 0.05)。总体而言,农业部门的病例明显减少(p < 0.001),而工业制造部门的病例则有所增加(p < 0.01)。在研究期间,农用制剂导致的病例数明显下降,而金属加工液(MWF)则被发现是2018年以来最常见的过敏性呼吸道疾病病因:这项研究发现,OA 病例数量有所减少,与 OA 和 OHP 相关的经济部门和致病因子也发生了变化,特别是在农业部门,来自工业制造部门的 MWFs 现在是最常见的致病因子。
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引用次数: 0
Comparison of cervical cancer screening models based on Pap and HPV tests in Tbilisi, Georgia. 格鲁吉亚第比利斯基于巴氏试验和 HPV 试验的宫颈癌筛查模式比较。
IF 1.1 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-09-01 DOI: 10.21101/cejph.a8014
Eter Kiguradze, Tamar Skhirtladze, Nikoloz Chkhartishvili, Tamuna Gogoladze, Nino Chikhladze, Tamar Alibegashvili

Objective: The objective of this study was to evaluate the effectiveness of human papillomavirus HPV test with HPV16/18 genotyping and liquid-based cytology (LBC) triage as a primary screening method for cervical cancer compared to conventional Pap test in women undergoing routine cervical cancer screening in Tbilisi.

Methods: Cross-sectional, prospective study was conducted, where 1,000 enrolled women aged 30-60 years during one visit underwent conventional Pap smear and Hr-HPV testing (Roche Cobas system). Women with any positive screening results were referred for further evaluation and remaining cells from the Cell Collection Medium vial were used for LBC. The study calculated sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) for each screening method and receiver-operating characteristic (ROC) curve to evaluate the accuracy of each diagnostic method in identifying people with CIN2+ diseases.

Results: The HPV test with HPV16/18 genotyping and LBC triage demonstrated higher sensitivity (76.9%), specificity (71.6%), and PPV (34.5%) compared to conventional Pap tests (p < 0.05). NPV was also high with the HPV test (94.1%). The HPV test alone had the highest sensitivity (92.3%) and NPV (96.7%), but lower specificity (41.4%) and PPV (22.6%) than the HPV test with HPV16/18 genotyping and LBC triage (p < 0.05). Comparing the areas under the curve (AUCs), only the HPV with HPV16/18 genotyping and LBC triage showed a statistically significant difference when compared to conventional Pap (0.71 vs. 0.55, p = 0.03) and high figures of AUC 0.71 (95% CI: 0.58-0.85) suggesting that HPV test with HPV16/18 genotyping and LBC triage is a more reliable screening method for detecting CIN2+ disease and preventing cervical cancer, than other screening modality.

Conclusion: The results suggest that the HPV test with HPV16/18 genotyping and LBC triage is a more effective primary screening method compared to conventional Pap tests. This information should be the basis for transition from cytological screening to HPV testing in Georgia.

研究目的本研究的目的是评估在第比利斯接受常规宫颈癌筛查的妇女中,与传统巴氏涂片检查相比,采用人乳头瘤病毒 HPV 检测(HPV16/18 基因分型)和液基细胞学(LBC)分诊作为宫颈癌初筛方法的有效性:进行了横断面前瞻性研究,对 1000 名 30-60 岁的妇女进行了一次常规巴氏涂片和 Hr-HPV 检测(罗氏 Cobas 系统)。筛查结果呈阳性的妇女将被转诊接受进一步评估,细胞采集培养基瓶中的剩余细胞将用于 LBC。研究计算了每种筛查方法的敏感性、特异性、阳性预测值(PPV)和阴性预测值(NPV),并绘制了接收者操作特征曲线(ROC),以评估每种诊断方法在识别 CIN2+ 疾病患者方面的准确性:与传统的巴氏试验相比,HPV16/18 基因分型和 LBC 分流试验的灵敏度(76.9%)、特异性(71.6%)和 PPV(34.5%)均较高(P < 0.05)。HPV 检测的 NPV 也很高(94.1%)。单用HPV检测的灵敏度(92.3%)和NPV(96.7%)最高,但特异性(41.4%)和PPV(22.6%)低于HPV16/18基因分型和LBC分流的HPV检测(p < 0.05)。比较曲线下面积(AUC),只有HPV16/18基因分型和LBC分流的HPV检测与传统巴氏涂片相比有显著的统计学差异(0.71 vs. 0.55, p = 0.03),AUC为0.71 (95% CI: 0.58-0.85),表明HPV16/18基因分型和LBC分流的HPV检测是一种比其他筛查方法更可靠的检测CIN2+疾病和预防宫颈癌的筛查方法:结果表明,与传统的巴氏试验相比,HPV16/18 基因分型和 LBC 分流试验是一种更有效的初级筛查方法。这些信息应作为格鲁吉亚从细胞学筛查过渡到 HPV 检测的依据。
{"title":"Comparison of cervical cancer screening models based on Pap and HPV tests in Tbilisi, Georgia.","authors":"Eter Kiguradze, Tamar Skhirtladze, Nikoloz Chkhartishvili, Tamuna Gogoladze, Nino Chikhladze, Tamar Alibegashvili","doi":"10.21101/cejph.a8014","DOIUrl":"10.21101/cejph.a8014","url":null,"abstract":"<p><strong>Objective: </strong>The objective of this study was to evaluate the effectiveness of human papillomavirus HPV test with HPV16/18 genotyping and liquid-based cytology (LBC) triage as a primary screening method for cervical cancer compared to conventional Pap test in women undergoing routine cervical cancer screening in Tbilisi.</p><p><strong>Methods: </strong>Cross-sectional, prospective study was conducted, where 1,000 enrolled women aged 30-60 years during one visit underwent conventional Pap smear and Hr-HPV testing (Roche Cobas system). Women with any positive screening results were referred for further evaluation and remaining cells from the Cell Collection Medium vial were used for LBC. The study calculated sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) for each screening method and receiver-operating characteristic (ROC) curve to evaluate the accuracy of each diagnostic method in identifying people with CIN2+ diseases.</p><p><strong>Results: </strong>The HPV test with HPV16/18 genotyping and LBC triage demonstrated higher sensitivity (76.9%), specificity (71.6%), and PPV (34.5%) compared to conventional Pap tests (p < 0.05). NPV was also high with the HPV test (94.1%). The HPV test alone had the highest sensitivity (92.3%) and NPV (96.7%), but lower specificity (41.4%) and PPV (22.6%) than the HPV test with HPV16/18 genotyping and LBC triage (p < 0.05). Comparing the areas under the curve (AUCs), only the HPV with HPV16/18 genotyping and LBC triage showed a statistically significant difference when compared to conventional Pap (0.71 vs. 0.55, p = 0.03) and high figures of AUC 0.71 (95% CI: 0.58-0.85) suggesting that HPV test with HPV16/18 genotyping and LBC triage is a more reliable screening method for detecting CIN2+ disease and preventing cervical cancer, than other screening modality.</p><p><strong>Conclusion: </strong>The results suggest that the HPV test with HPV16/18 genotyping and LBC triage is a more effective primary screening method compared to conventional Pap tests. This information should be the basis for transition from cytological screening to HPV testing in Georgia.</p>","PeriodicalId":9823,"journal":{"name":"Central European journal of public health","volume":"32 3","pages":"166-172"},"PeriodicalIF":1.1,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142342579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Occurrence of adverse events following vaccination in patients with allergies: a prospective study. 过敏症患者接种疫苗后的不良反应发生率:一项前瞻性研究。
IF 1.1 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-09-01 DOI: 10.21101/cejph.a8170
Petra Macounová, Hana Tomášková, Rastislav Maďar

Objectives: Allergic patients may be concerned about more frequent and/or more severe adverse events following vaccination, which may lead to the refusal of vaccines among these patients. The aim of this study is to assess whether allergic patients have more frequent adverse events (AEs) after vaccination than healthy individuals.

Methods: Study participants (N = 591) underwent vaccination of their choice at a selected Vaccination and Travel Medicine Centre. At a 10 to 14-day interval, they were contacted for a telephone questionnaire survey on the occurrence of AEs after vaccination. A group of allergic patients (n = 188) and healthy controls (n = 403) were followed in the study.

Results: No significant difference was found in the occurrence of AEs between study and control group. Only in redness and swelling, which was more common in allergic patients, but only in a few individuals. All side effects were minor, such as pain at the injection site or fatigue. No participant experienced a serious or life-threatening adverse event. In the studied group, no statistically significant differences were found even in the occurrence of AEs after singular vs. simultaneous administration of vaccines (p = 0.094), nor after vaccination with inactivated vs. attenuated vaccines (p = 0.655), or after vaccination against bacterial vs. viral infections (p = 0.140).

Conclusions: Vaccination of allergic patients did not cause more frequent and/or more serious adverse events in our study compared to healthy people. If general contraindications are observed, then vaccination of allergic patients is considered safe.

目的:过敏症患者可能会担心接种疫苗后出现更频繁和/或更严重的不良反应,这可能会导致这些患者拒绝接种疫苗。本研究旨在评估过敏症患者接种疫苗后是否会比健康人更频繁地出现不良反应(AEs):方法:研究参与者(N = 591)在选定的疫苗接种和旅行医学中心接种自己选择的疫苗。每隔 10 到 14 天,研究人员会与他们取得联系,就接种疫苗后出现的 AEs 进行电话问卷调查。研究跟踪了一组过敏症患者(188 人)和健康对照组(403 人):结果:研究组和对照组的过敏反应发生率无明显差异。只有红肿在过敏患者中更为常见,但仅在少数人中出现。所有副作用都很轻微,如注射部位疼痛或疲劳。没有人出现严重或危及生命的不良反应。在研究组中,即使在单次接种疫苗与同时接种疫苗(P = 0.094)、接种灭活疫苗与接种减毒疫苗(P = 0.655)、接种细菌感染疫苗与接种病毒感染疫苗(P = 0.140)后,不良反应的发生率也没有发现明显的统计学差异:结论:在我们的研究中,与健康人相比,过敏症患者接种疫苗不会引起更频繁和/或更严重的不良反应。结论:在我们的研究中,与健康人相比,过敏症患者接种疫苗不会引起更频繁和/或更严重的不良反应。如果有一般禁忌症,过敏症患者接种疫苗是安全的。
{"title":"Occurrence of adverse events following vaccination in patients with allergies: a prospective study.","authors":"Petra Macounová, Hana Tomášková, Rastislav Maďar","doi":"10.21101/cejph.a8170","DOIUrl":"https://doi.org/10.21101/cejph.a8170","url":null,"abstract":"<p><strong>Objectives: </strong>Allergic patients may be concerned about more frequent and/or more severe adverse events following vaccination, which may lead to the refusal of vaccines among these patients. The aim of this study is to assess whether allergic patients have more frequent adverse events (AEs) after vaccination than healthy individuals.</p><p><strong>Methods: </strong>Study participants (N = 591) underwent vaccination of their choice at a selected Vaccination and Travel Medicine Centre. At a 10 to 14-day interval, they were contacted for a telephone questionnaire survey on the occurrence of AEs after vaccination. A group of allergic patients (n = 188) and healthy controls (n = 403) were followed in the study.</p><p><strong>Results: </strong>No significant difference was found in the occurrence of AEs between study and control group. Only in redness and swelling, which was more common in allergic patients, but only in a few individuals. All side effects were minor, such as pain at the injection site or fatigue. No participant experienced a serious or life-threatening adverse event. In the studied group, no statistically significant differences were found even in the occurrence of AEs after singular vs. simultaneous administration of vaccines (p = 0.094), nor after vaccination with inactivated vs. attenuated vaccines (p = 0.655), or after vaccination against bacterial vs. viral infections (p = 0.140).</p><p><strong>Conclusions: </strong>Vaccination of allergic patients did not cause more frequent and/or more serious adverse events in our study compared to healthy people. If general contraindications are observed, then vaccination of allergic patients is considered safe.</p>","PeriodicalId":9823,"journal":{"name":"Central European journal of public health","volume":"32 3","pages":"147-154"},"PeriodicalIF":1.1,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142342600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Central European journal of public health
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