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Thirteen-year surveillance results of acute flaccid paralysis cases in Southeast Turkey and the effect of refugee movements on surveillance results. 土耳其东南部急性弛缓性麻痹病例的十三年监测结果以及难民流动对监测结果的影响。
IF 1.2 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-03-01 DOI: 10.21101/cejph.a7605
Nezir Özgün, Gülnaz Kubat, Birgül Turan, Mert Özgün, İzzettin Toktaş, Gülay Korukluoğlu

Objective: Acute flaccid paralysis (AFP) is a major neurological problem. Turkey has accepted over 4 million refugees since 2011 due to the wars in neighbouring countries. In the long term, refugees can have adverse effects on the limited resources of health, sanitation, water supply, foodstuff, and shelter services of host countries, precipitating the transmission and spread of enteroviruses causing AFP. This study examines the 13-year surveillance and incidence of AFP cases in southeast Turkey, and questions possible impact of refugee movements on these parameters, comparing the periods before (2007-2010) and after (2011-2019) 2011, when the refugee movements emerged.

Methods: The records of cases reported from southeast part of Turkey with suspected AFP between January 2007 and December 2019 were reviewed retrospectively.

Results: Of the patients, 121 (58.5%) were male. Mean age was 80.36 ± 46.67 months. Eighty-five (41.1%) were aged 60 months or younger. The number of patients under 60 months increased significantly after 2011. Mean incidence was calculated as 0.88 cases/100,000 person years versus 1.58 cases/100,000 person years in the period before and after 2011, respectively. Guillain-Barré syndrome (GBS) was the most common cause of AFP in both periods. As of 2011, however, the incidence of acute transverse myelitis increased approximately 4 times and GBS decreased proportionally. Non-polio enteroviruses were the most frequent isolates, detected from 9.1% of stool samples.

Conclusion: Although refugee movements appear to may have adverse effects on AFP incidence and surveillance outcomes, larger studies involving the whole country, particularly at places where no refugees settled, are needed to achieve more conclusive evidence.

目的:急性弛缓性麻痹(AFP)是一个主要的神经系统问题。自 2011 年以来,由于邻国的战争,土耳其接收了 400 多万难民。从长远来看,难民可能会对收容国有限的医疗、卫生、供水、食品和住房服务资源造成不利影响,从而加剧导致急性弛缓性麻痹的肠道病毒的传播和扩散。本研究对土耳其东南部13年来的甲型肝炎病例监测和发病情况进行了研究,并比较了难民潮出现之前(2007-2010年)和之后(2011-2019年)的情况,探讨了难民潮对这些参数可能产生的影响:方法:回顾性审查了2007年1月至2019年12月期间土耳其东南部报告的疑似甲胎蛋白病例记录:结果:121 例(58.5%)患者为男性。平均年龄为(80.36 ± 46.67)个月。85人(41.1%)的年龄在60个月或以下。2011 年后,60 个月以下的患者人数明显增加。2011年之前和之后的平均发病率分别为0.88例/100,000人年和1.58例/100,000人年。在这两个时期,吉兰-巴雷综合征(GBS)是导致甲胎蛋白缺乏症的最常见原因。但截至 2011 年,急性横贯性脊髓炎的发病率增加了约 4 倍,而吉兰-巴雷综合征的发病率则成比例下降。非脊髓灰质炎肠道病毒是最常见的分离物,从9.1%的粪便样本中检出:尽管难民流动似乎可能对甲型肝炎的发病率和监测结果产生不利影响,但要获得更确凿的证据,还需要在全国范围内,特别是在没有难民定居的地方开展更大规模的研究。
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引用次数: 0
The relationship between atherosclerosis and dementia. 动脉粥样硬化与痴呆症之间的关系。
IF 1.2 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-03-01 DOI: 10.21101/cejph.a7848
Jana Janoutová, Ondřej Machaczka, Martina Kovalová, Anna Zatloukalová, Petr Ambroz, Veronika Koutná, Eva Mrázková, Michal Bar, Martin Roubec, Petra Bártová, Richard Novobilský, Martin Sabela, Pavlína Kušnierová, David Stejskal, Lucie Faldynová, Sylwia Walczysková, Martin Vališ, Lukáš Školoudík, Petra Šolínová, David Školoudík, Vladimír Janout

Objective: The main objective is to confirm a hypothesis that atherosclerosis, through various mechanisms, considerably influences cognitive impairment and significantly increases the risk for developing dementia. Complete sample should be 920 individuals. The present study aimed to analyse epidemiological data from a questionnaire survey.

Methods: The work was carried out in the form of an epidemiological case control study. Subjects are enrolled in the study based on results of the following examinations carried out in neurology departments and outpatient centres during the project NU20-09-00119 from 2020 to 2023. Respondents were divided into four research groups according to the results of clinical examination for the presence of atherosclerosis and dementia. The survey was mainly concerned with risk factors for both atherosclerosis and dementia. It contained questions on lifestyle factors, cardiovascular risk factors, leisure activities, and hobbies.

Results: Analysis of the as yet incomplete sample of 877 subjects has yielded the following selected results: on average, 16% of subjects without dementia had primary education while the proportion was 45.2% in the group with both dementia and atherosclerosis. Subjects with dementia did mainly physical work. Low physical activity was more frequently noted in dementia groups (Group 2 - 54.4% and Group 3 - 47.2%) than in subjects without dementia (Group 1 - 19.6% and Group 4 - 25.8%). Coronary heart disease was more frequently reported by dementia patients (33.95%) than those without dementia (16.05%).

Conclusion: Cognitively impaired individuals, in particular those with vascular cognitive impairment, have poorer quality of life and shorter survival. Risk factors contributing to such impairment are similar to those for ischaemic or haemorrhagic stroke. It may be concluded that most of the analysed risk factors play a role in the development of both atherosclerosis and dementia.

研究目的主要目的是证实一个假设,即动脉粥样硬化通过各种机制严重影响认知障碍,并显著增加患痴呆症的风险。完整样本应为 920 人。本研究旨在分析通过问卷调查获得的流行病学数据:工作以流行病学病例对照研究的形式进行。研究对象是根据 2020 年至 2023 年 NU20-09-00119 项目期间在神经内科和门诊中心进行的下列检查结果招募的。根据是否存在动脉粥样硬化和痴呆症的临床检查结果,受访者被分为四个研究小组。调查主要涉及动脉粥样硬化和痴呆症的风险因素。调查内容包括生活方式因素、心血管风险因素、休闲活动和业余爱好等问题:对尚未完成的 877 名受试者样本进行分析后,得出以下部分结果:平均而言,16% 的非痴呆症受试者受过初等教育,而在同时患有痴呆症和动脉粥样硬化症的群体中,这一比例为 45.2%。痴呆症患者主要从事体力劳动。痴呆症组(第 2 组 - 54.4%,第 3 组 - 47.2%)比无痴呆症组(第 1 组 - 19.6%,第 4 组 - 25.8%)更经常出现体力活动少的情况。与无痴呆症患者(16.05%)相比,痴呆症患者(33.95%)更经常报告冠心病:结论:认知障碍患者,尤其是血管性认知障碍患者,生活质量较差,存活时间较短。导致认知障碍的风险因素与缺血性或出血性中风相似。由此可以得出结论,大部分分析的风险因素在动脉粥样硬化和痴呆症的发展过程中都起到了一定的作用。
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引用次数: 0
Physical activity and mental health of medical students. 医学生的体育活动和心理健康。
IF 1.2 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-03-01 DOI: 10.21101/cejph.a8097
Konstantinos Stratakis, Zorica Terzić-Šupić, Jovana Todorović, Dejan Nešić, Ivana Novaković

Objective: Medical students usually do not meet the recommendations on the minimum level of physical activity, despite knowing the impact that physical activity has on the prevention and treatment of various diseases. Medical students are considered to be insufficiently physically active. The aim of this study is to determine the prevalence of physically active fifth-year medical students at five universities in Serbia, as well as to identify factors associated with insufficient physical activity of students.

Methods: A cross-sectional study was performed in the population of fifth-year medical students from five different universities in Serbia. The research instrument was a questionnaire specially designed based on similar research. Descriptive and analytical statistics methods were used in statistical analysis.

Results: The study included a total of 573 fifth-year medical students from five universities in Serbia: 311 (54.3%) Belgrade; 86 (15.0%) Kragujevac; 58 (10.1%) Nis; 66 (11.5%) Kosovska Mitrovica; 52 (9.1%) Novi Sad. Insufficient physical activity was statistically significantly associated with studying at the University of Kosovska Mitrovica (OR = 3.98, 95% CI: 1.83-8.57). There was a statistically significant difference in the frequency of anti-anxiety medications use in the last 12 months between students with sufficient and insufficient physical activity (p = 0.040) as well as in the average number of cigarettes smoked per day between students with sufficient and those with insufficient physical activity (2.82 ± 6.35 vs. 4.50 ± 8.29, p = 0.043). There was also a statistically significant difference in the average score on the Beck's depression scale between students with sufficient and students with insufficient physical activity (6.51 ± 6.59 vs. 10.03 ± 9.37, p < 0.001) and in the average score on Zung's anxiety scale (34.86 ± 8.18 vs. 38.07 ± 8.71, p = 0.003).

Conclusion: A high percentage of medical faculty students (86.6%) are physically active. Differences in the level of physical activity were observed between students of these five universities as well as between students with different levels of physical activity.

目的尽管知道体育锻炼对预防和治疗各种疾病的影响,但医科学生通常达不到最低体育锻炼水平的建议。医科学生被认为体力活动不足。本研究的目的是确定塞尔维亚五所大学五年级医学生体育锻炼的普遍程度,并找出与学生体育锻炼不足有关的因素:这项横断面研究的对象是塞尔维亚五所不同大学的五年级医学生。研究工具是根据类似研究专门设计的调查问卷。统计分析采用了描述性和分析性统计方法:研究对象包括塞尔维亚五所大学共 573 名五年级医学生:贝尔格莱德 311 人(54.3%);克拉古耶瓦茨 86 人(15.0%);尼什 58 人(10.1%);科索夫斯卡-米特罗维察 66 人(11.5%);诺维萨德 52 人(9.1%)。据统计,体力活动不足与在科索夫斯卡-米特罗维察大学学习有显著关联(OR = 3.98,95% CI:1.83-8.57)。在过去 12 个月中使用抗焦虑药物的频率方面,体育锻炼充足的学生与体育锻炼不足的学生之间存在统计学意义上的显著差异(p = 0.040);在平均每天吸烟数量方面,体育锻炼充足的学生与体育锻炼不足的学生之间也存在统计学意义上的显著差异(2.82 ± 6.35 vs. 4.50 ± 8.29,p = 0.043)。体育锻炼充足的学生与体育锻炼不足的学生在贝克抑郁量表的平均得分(6.51 ± 6.59 vs. 10.03 ± 9.37,p < 0.001)和Zung焦虑量表的平均得分(34.86 ± 8.18 vs. 38.07 ± 8.71,p = 0.003)方面也存在显著差异:结论:医学系学生中参加体育锻炼的比例较高(86.6%)。这五所大学的学生之间以及不同体育锻炼水平的学生之间的体育锻炼水平存在差异。
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引用次数: 0
Prevalence of risk factors for development of cardiovascular diseases in urban and rural areas of Eastern Croatia: a cross-sectional study. 克罗地亚东部城市和农村地区心血管疾病发病风险因素的流行情况:一项横断面研究。
IF 1.2 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-03-01 DOI: 10.21101/cejph.a7709
Mirta Klapec-Basar, Tanja Kovač, Renata Apatić, Željko Mudri, Tin Basar, Stjepan Jurić, Rudika Gmajnić, Robert Lovrić

Objective: Cardiovascular diseases are the leading global cause of death. Due to the disparities in cardiovascular risk factors between rural and urban populations, this study aims to assess the differences in the prevalence of risk factors in urban and rural areas of eastern Croatia.

Methods: The cross-sectional study included 280 participants (140 from urban and 140 from rural areas) registered at studied general practice offices. Methods included e-health records, questionnaire, physical examination methods, and blood sampling for laboratory tests.

Results: The most common risk factors among participants were elevated total cholesterol (83.6%), elevated LDL cholesterol (81.8%), increased body mass index (75.0%), increased waist-hip ratio (82.9%), increased waist circumference (63.2%), and arterial hypertension (70.1%). The rural participants had a significantly higher prevalence of arterial hypertension (p = 0.023), increased body mass index (p = 0.004), increased waist circumference (p = 0.004), increased waist-hip ratio (p < 0.001), and increased LDL cholesterol (p = 0.029), while the urban participants had a significantly higher prevalence of insufficient physical activity (p < 0.001).

Conclusions: In the examined sample, the prevalence of cardiovascular risk factors is generally high. Participants from rural areas are significantly more susceptible to cardiovascular risk factors than participants from urban areas.

目的:心血管疾病是导致全球死亡的主要原因。由于农村和城市人口在心血管风险因素方面存在差异,本研究旨在评估克罗地亚东部城市和农村地区风险因素流行率的差异:这项横断面研究包括在所研究的全科诊所登记的 280 名参与者(140 名来自城市地区,140 名来自农村地区)。研究方法包括电子健康记录、问卷调查、体格检查方法和抽血化验:参与者中最常见的风险因素是总胆固醇升高(83.6%)、低密度脂蛋白胆固醇升高(81.8%)、体重指数增加(75.0%)、腰臀比增加(82.9%)、腰围增加(63.2%)和动脉高血压(70.1%)。农村参与者的动脉高血压患病率(p = 0.023)、体重指数增加(p = 0.004)、腰围增加(p = 0.004)、腰臀比增加(p < 0.001)和低密度脂蛋白胆固醇增加(p = 0.029)明显高于城市参与者,而体力活动不足的患病率明显高于城市参与者(p < 0.001):结论:在所调查的样本中,心血管风险因素的发生率普遍较高。结论:在所调查的样本中,心血管风险因素的发生率普遍较高,来自农村地区的参与者比来自城市地区的参与者更容易受到心血管风险因素的影响。
{"title":"Prevalence of risk factors for development of cardiovascular diseases in urban and rural areas of Eastern Croatia: a cross-sectional study.","authors":"Mirta Klapec-Basar, Tanja Kovač, Renata Apatić, Željko Mudri, Tin Basar, Stjepan Jurić, Rudika Gmajnić, Robert Lovrić","doi":"10.21101/cejph.a7709","DOIUrl":"https://doi.org/10.21101/cejph.a7709","url":null,"abstract":"<p><strong>Objective: </strong>Cardiovascular diseases are the leading global cause of death. Due to the disparities in cardiovascular risk factors between rural and urban populations, this study aims to assess the differences in the prevalence of risk factors in urban and rural areas of eastern Croatia.</p><p><strong>Methods: </strong>The cross-sectional study included 280 participants (140 from urban and 140 from rural areas) registered at studied general practice offices. Methods included e-health records, questionnaire, physical examination methods, and blood sampling for laboratory tests.</p><p><strong>Results: </strong>The most common risk factors among participants were elevated total cholesterol (83.6%), elevated LDL cholesterol (81.8%), increased body mass index (75.0%), increased waist-hip ratio (82.9%), increased waist circumference (63.2%), and arterial hypertension (70.1%). The rural participants had a significantly higher prevalence of arterial hypertension (p = 0.023), increased body mass index (p = 0.004), increased waist circumference (p = 0.004), increased waist-hip ratio (p < 0.001), and increased LDL cholesterol (p = 0.029), while the urban participants had a significantly higher prevalence of insufficient physical activity (p < 0.001).</p><p><strong>Conclusions: </strong>In the examined sample, the prevalence of cardiovascular risk factors is generally high. Participants from rural areas are significantly more susceptible to cardiovascular risk factors than participants from urban areas.</p>","PeriodicalId":9823,"journal":{"name":"Central European journal of public health","volume":"32 1","pages":"16-24"},"PeriodicalIF":1.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140856589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metabolically healthy obesity and health risks - a review of meta-analyses. 代谢健康的肥胖与健康风险--荟萃分析综述。
IF 1.2 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-03-01 DOI: 10.21101/cejph.a7806
Erika Čermáková, Martin Forejt

Objective: This article briefly summarizes the results of existing research on metabolically healthy obesity in the context of health risks.

Methods: The PubMed database was searched for relevant meta-analyses addressing metabolically healthy obesity in the context of health risks.

Results: We included a total of 17 relevant meta-analyses in this review. The results of the studied meta-analyses showed that metabolically healthy obesity may be only a transient condition associated with an increased risk of developing metabolic abnormalities in the future. People with obesity without metabolic abnormalities have an increased risk of type 2 diabetes, cardiovascular disease, cancer, chronic kidney disease, and depressive syndrome. In addition, all people with obesity are at risk of pathogenesis resulting from the mechanical stress caused by presence of abnormal adipose tissue, such as sleep apnoea syndrome or skin problems.

Conclusion: Based on the results of meta-analyses, we recommend motivating all obese patients to change their lifestyle regardless of the presence of metabolic defects.

摘要本文简要总结了在健康风险背景下有关代谢健康型肥胖的现有研究成果:方法:在 PubMed 数据库中搜索针对健康风险背景下代谢健康型肥胖的相关荟萃分析:本综述共纳入了 17 项相关的荟萃分析。所研究的荟萃分析结果表明,代谢健康型肥胖可能只是一种短暂的状况,与未来发生代谢异常的风险增加有关。没有代谢异常的肥胖症患者罹患 2 型糖尿病、心血管疾病、癌症、慢性肾病和抑郁综合征的风险会增加。此外,所有肥胖症患者都有可能因异常脂肪组织造成的机械压力而发病,如睡眠呼吸暂停综合征或皮肤问题:根据荟萃分析的结果,我们建议激励所有肥胖患者改变生活方式,无论是否存在代谢缺陷。
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引用次数: 0
Association of cardiovascular health and educational status in a screening cohort. 筛查队列中心血管健康与教育状况的关系。
IF 1.2 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-03-01 DOI: 10.21101/cejph.a7818
Sarah Wernly, Georg Semmler, Maria Flamm, Andreas Völkerer, Ralf Erkens, Elmar Aigner, Christian Datz, Bernhard Wernly

Introduction: The global burden of chronic diseases, including cardiovascular disease, remains a significant public health challenge. The Life's Simple 7 (LS7) score was developed as a tool to evaluate cardiovascular health behaviours and habits and identify high-risk individuals. The present study aimed to assess the distribution of LS7 scores among educational strata.

Methods: The study population consisted of 3,383 asymptomatic individuals screened for colorectal cancer at a single centre in Austria. We split patients into lower (n = 1,055), medium (n = 1,997), and higher (n = 331) education, based on the International Standard Classification of Education (ISCED). Cox regression models were utilized to determine the association between education and mortality over a median follow-up period of 7 years.

Results: Individuals with higher educational status had a significantly higher prevalence of ideal cardiovascular health metrics, as defined by the LS7 score, compared to those with medium and lower educational status: n = 94 (28%) vs. n = 347 (17%) and n = 84 (8%), respectively, (p < 0.001). In the Cox regression analysis, both medium (HR = 0.61, 95% CI: 0.43-0.84, p < 0.001) and higher educational status (HR = 0.44, 95% CI: 0.19-1.01, p = 0.06) were associated with all-cause mortality, as was the LS7.

Conclusion: Our findings highlight a significant association between lower educational status and poorer cardiovascular health, as assessed by LS7, which persisted even after multivariable adjustment. Additionally, both educational status and LS7 were associated with increased mortality, underscoring the significance of our results. These findings have important implications for public health, as screening and prevention strategies may need to be tailored to meet the diverse educational backgrounds of individuals, given the higher prevalence of unhealthy lifestyle behaviours among those with lower educational status.

导言:包括心血管疾病在内的慢性疾病给全球造成的负担仍然是一项重大的公共卫生挑战。生命简单 7(LS7)评分是作为评估心血管健康行为和习惯以及识别高危人群的工具而开发的。本研究旨在评估 LS7 分数在不同教育阶层的分布情况:研究对象包括在奥地利一家中心接受大肠癌筛查的 3,383 名无症状者。根据国际标准教育分类(ISCED),我们将患者分为低教育程度(n = 1,055)、中等教育程度(n = 1,997)和高等教育程度(n = 331)。利用 Cox 回归模型确定教育程度与中位随访 7 年的死亡率之间的关系:结果:与教育程度中等和较低的人相比,教育程度较高的人根据 LS7 分数定义的理想心血管健康指标的患病率明显更高:分别为 94(28%)对 347(17%)和 84(8%)(P < 0.001)。在 Cox 回归分析中,中等(HR = 0.61,95% CI:0.43-0.84,p < 0.001)和较高的教育程度(HR = 0.44,95% CI:0.19-1.01,p = 0.06)与全因死亡率相关,LS7 也是如此:我们的研究结果表明,根据 LS7 评估,教育程度较低与心血管健康状况较差之间存在显著关联,即使经过多变量调整后,这种关联依然存在。此外,教育状况和 LS7 都与死亡率增加有关,这突出了我们研究结果的重要性。这些发现对公共卫生具有重要意义,因为鉴于教育程度较低的人中不健康生活方式行为的发生率较高,筛查和预防策略可能需要根据个人的不同教育背景而量身定制。
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引用次数: 0
History of development of undergraduate public health education in Bulgaria. 保加利亚公共卫生本科教育发展史。
IF 1.2 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-03-01 DOI: 10.21101/cejph.a7928
Valentina Alexandrova, Klara Dokova

Objective: The study aims to present a historical review and analysis of the establishment and development of undergraduate public health (PH) education in Bulgaria from 1878 until 2019.

Methods: А search and selection of historical documents was performed, including laws, rules, regulations, government plans, programmes, scientific publications from periodical medical press, journals, specialized monographs, and books. A retrospective analysis of the normative documents related to the organization of the sanitation and public health activities, and to the provision of professional undergraduate education of the public health workforce in Bulgaria has been carried out. The required competences and tasks of the specialists exercising public health control services were extracted.

Results: The development in the public health educational activities were followed in three consecutive periods: the newly independent state (1878-1944); the socialist state (1945-1990); the democratizing state (1990-2019). The development of organized PH activities began after the liberation of Bulgaria in 1878. The historical analysis reveals a direct link between the major socioeconomic changes in the country and the organization of PH undergraduate education which passed through dynamic transformations. The professional education in the sphere of PH started with the training of feldshers, followed by sanitary feldsher and sanitary health inspectors performed in secondary vocational medical schools during the socialist period, reaching the stage of undergraduate university PH education provided by medical colleges associated with universities in the third period.

Conclusion: Despite the continuous development in the organization of undergraduate PH education in Bulgaria, its content is still not fully compatible with the basic European PH services and actions. There is a growing need for wider standardization and integration of undergraduate PH education in the EU so that the specialty can reach the status of a regulated health profession similar to medicine, nursing, and others.

研究目的本研究旨在对 1878 年至 2019 年保加利亚公共卫生(PH)本科教育的建立和发展进行历史回顾和分析:对历史文献进行了搜索和筛选,包括法律、法规、规章、政府计划、方案、期刊医学出版物、期刊、专业专著和书籍。对与保加利亚卫生和公共卫生活动的组织以及公共卫生工作人员的本科专业教育有关的规范性文件进行了回顾性分析。研究提取了公共卫生控制服务专家所需的能力和任务:公共卫生教育活动的发展经历了三个连续时期:新独立国家(1878-1944 年);社会主义国家(1945-1990 年);民主化国家(1990-2019 年)。有组织的公共卫生活动的发展始于 1878 年保加利亚解放后。历史分析表明,保加利亚的重大社会经济变革与经过动态变革的 PH 本科教育组织之间存在直接联系。卫生学领域的专业教育从培养长炉工开始,随后是社会主义时期在中等职业医学院培养卫生长炉工和卫生健康督察员,在第三个时期达到了由与大学有联系的医学院提供大学本科卫生学教育的阶段:尽管保加利亚本科卫生学教育的组织工作在不断发展,但其内容仍不完全符合欧洲基本的卫生学服务和行动。欧盟越来越需要对本科生的公共卫生教育进行更广泛的标准化和整合,从而使该专业与医学、护理学和其他专业一样,成为受监管的卫生专业。
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引用次数: 0
Are the elements zinc, copper, magnesium, and rubidium related to nutrition and iodine deficiency in pregnant Bulgarian women from iodine deficient region? 缺碘地区的保加利亚孕妇体内的锌、铜、镁和铷元素是否与营养和碘缺乏有关?
IF 1.2 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-03-01 DOI: 10.21101/cejph.a7796
Mariana Georgieva Bacelova, Penka Dimitrova Gatseva, Tanya Ivanova Deneva, Delyana Miteva Davcheva, Anelia Veselinova Bivolarska

Objective: Trace elements are essential for the biochemistry of the cell. Their reference values have been found to differ considerably in pregnant women stratified by age, place of residence, anthropometric status, and length of pregnancy. In optimal amounts, these elements reduce the risk of pregnancy complications. Subclinical hypothyroidism in pregnancy is associated with adverse maternal and neonatal outcomes. The aim of the study was to determine the effects of zinc (Zn), copper (Cu), magnesium (Mg), and rubidium (Rb) on pregnant women in an iodine deficiency region and find the relationship with the thyroid status and nutrition.

Methods: We evaluated the iodine status of 61 healthy pregnant women from an iodine deficient region in Bulgaria. Thyroid stimulating hormone (TSH) and thyroxin free (FT4) levels were measured using ELISA.

Results: We found elevated levels of copper that differed the most between the first and second trimesters; Cu and TSH were found to be positively correlated (р < 0.05). Lower Cu levels were found in pregnant women consuming pulses more than 2-3 times a week (р = 0.033). The women consuming fish more than 2-3 times a week had higher levels of Rb. We found a pronounced iodine deficiency in more than half of the examined women in the first to third trimesters, without any effect of pregnancy on the ioduria (р=0.834). All second and third trimester cases were associated with severe ioduria (< 150 µg/L).

Conclusion: The high Cu levels were associated with subclinical hypothyroidism (SCH) and less pulse consumption during pregnancy in an iodine deficiency endemic area. SCH was found in 24% of the pregnant women in such an area while in 13% of them SCH had progressed to overt hypothyroidism.

目的:微量元素对细胞的生物化学至关重要。根据年龄、居住地、人体测量状况和怀孕时间的不同,孕妇体内微量元素的参考值也大不相同。这些元素的最佳含量可降低妊娠并发症的风险。妊娠期亚临床甲状腺功能减退症与不良的孕产妇和新生儿结局有关。本研究旨在确定锌(Zn)、铜(Cu)、镁(Mg)和铷(Rb)对缺碘地区孕妇的影响,并找出其与甲状腺状态和营养的关系:我们对保加利亚缺碘地区 61 名健康孕妇的碘状况进行了评估。采用酶联免疫吸附法测定促甲状腺激素(TSH)和游离甲状腺素(FT4)水平:结果:我们发现铜含量升高的情况在妊娠前三个月和妊娠后三个月之间差异最大;铜与促甲状腺激素呈正相关(р < 0.05)。每周食用豆类 2-3 次以上的孕妇铜含量较低(р = 0.033)。每周食用鱼类超过 2-3 次的孕妇体内铷的含量较高。我们发现,在妊娠的前三个月至后三个月,半数以上的受检妇女明显缺碘,而妊娠对碘尿症没有任何影响(р=0.834)。所有第二和第三个孕期的病例都伴有严重的碘尿(< 150 µg/L):结论:在缺碘流行地区,高铜水平与亚临床甲状腺功能减退症(SCH)和孕期脉搏消耗量较少有关。在该地区,24%的孕妇患有亚临床甲状腺功能减退症,其中13%已发展为明显的甲状腺功能减退症。
{"title":"Are the elements zinc, copper, magnesium, and rubidium related to nutrition and iodine deficiency in pregnant Bulgarian women from iodine deficient region?","authors":"Mariana Georgieva Bacelova, Penka Dimitrova Gatseva, Tanya Ivanova Deneva, Delyana Miteva Davcheva, Anelia Veselinova Bivolarska","doi":"10.21101/cejph.a7796","DOIUrl":"https://doi.org/10.21101/cejph.a7796","url":null,"abstract":"<p><strong>Objective: </strong>Trace elements are essential for the biochemistry of the cell. Their reference values have been found to differ considerably in pregnant women stratified by age, place of residence, anthropometric status, and length of pregnancy. In optimal amounts, these elements reduce the risk of pregnancy complications. Subclinical hypothyroidism in pregnancy is associated with adverse maternal and neonatal outcomes. The aim of the study was to determine the effects of zinc (Zn), copper (Cu), magnesium (Mg), and rubidium (Rb) on pregnant women in an iodine deficiency region and find the relationship with the thyroid status and nutrition.</p><p><strong>Methods: </strong>We evaluated the iodine status of 61 healthy pregnant women from an iodine deficient region in Bulgaria. Thyroid stimulating hormone (TSH) and thyroxin free (FT4) levels were measured using ELISA.</p><p><strong>Results: </strong>We found elevated levels of copper that differed the most between the first and second trimesters; Cu and TSH were found to be positively correlated (р < 0.05). Lower Cu levels were found in pregnant women consuming pulses more than 2-3 times a week (р = 0.033). The women consuming fish more than 2-3 times a week had higher levels of Rb. We found a pronounced iodine deficiency in more than half of the examined women in the first to third trimesters, without any effect of pregnancy on the ioduria (р=0.834). All second and third trimester cases were associated with severe ioduria (< 150 µg/L).</p><p><strong>Conclusion: </strong>The high Cu levels were associated with subclinical hypothyroidism (SCH) and less pulse consumption during pregnancy in an iodine deficiency endemic area. SCH was found in 24% of the pregnant women in such an area while in 13% of them SCH had progressed to overt hypothyroidism.</p>","PeriodicalId":9823,"journal":{"name":"Central European journal of public health","volume":"32 1","pages":"31-38"},"PeriodicalIF":1.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140847541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Premature deaths from fine particles PM2.5 air pollution in regional capitals of Slovakia during 2016-2020 period. 2016-2020 年期间斯洛伐克各地区首府因细微颗粒 PM2.5 空气污染而过早死亡的人数。
IF 1.2 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-12-01 DOI: 10.21101/cejph.a7748
Adrián Ondrovič

Objectives: The purpose of this quantitative study is to assess the impact of fine particles air pollution in major cities of Slovakia. The study aims to estimate number of premature deaths from long-term exposure to fine particles PM2.5 in eight regional capitals of Slovakia in the period 2016-2020. Consequently, the study aims to conduct a comparative analysis using secondary derived indicators.

Methods: For calculations of estimated premature deaths from long-term exposure to fine particles PM2.5 air pollution we used standardized methodology developed by the World Health Organization and the European Environment Agency.

Results: The annual average of estimated premature deaths from PM2.5 air pollution in the studied period was in Bratislava 353, Košice 219, Prešov 84, Žilina 90, Banská Bystrica 76, Nitra 73, Trnava 59, and Trenčín 52. In relative terms per 1,000 inhabitants Bratislava had annual average 1.14 of estimated premature deaths, Košice 1.32, Prešov 1.38, Žilina 1.61, Banská Bystrica 1.35, Nitra 1.35, Trnava 1.27, and Trenčín 1.31. Bratislava as the largest city in Slovakia recorded the smallest relative number of estimated premature deaths. The worst results were recorded by the city of Žilina.

Conclusions: The estimated number of premature deaths from long-term exposure to particulate matter air pollution in the regional capitals decreased in the given period. The most of the regional capitals with the exception of Bratislava and Žilina, showed similar levels of estimated premature deaths. However, the current geopolitical situation and rising energy prices threaten return to solid fuel burning which is the largest source of particulate matter air pollution in Slovakia and thus reversing positive trends.

研究目的本定量研究旨在评估细颗粒物空气污染对斯洛伐克主要城市的影响。研究旨在估算 2016-2020 年期间斯洛伐克八个地区首府因长期暴露于细颗粒物 PM2.5 而过早死亡的人数。因此,该研究旨在利用二次衍生指标进行比较分析:在计算长期暴露于细颗粒物 PM2.5 空气污染导致的估计过早死亡人数时,我们采用了世界卫生组织和欧洲环境署制定的标准化方法:在研究期间,因 PM2.5 空气污染而过早死亡的年平均估计人数分别为:布拉迪斯拉发 353 人、科希策 219 人、普雷绍夫 84 人、日利纳 90 人、班斯卡-比斯特里察 76 人、尼特拉 73 人、特尔纳瓦 59 人和特伦钦 52 人。相对而言,布拉迪斯拉发每年平均每千名居民估计有 1.14 人过早死亡,科希策为 1.32 人,普列索夫为 1.38 人,日利纳为 1.61 人,班斯卡-比斯特里察为 1.35 人,尼特拉为 1.35 人,特尔纳瓦为 1.27 人,特伦钦为 1.31 人。作为斯洛伐克最大的城市,布拉迪斯拉发的估计过早死亡人数相对最少。日利纳市的结果最差:在此期间,各大区首府因长期暴露于颗粒物空气污染而过早死亡的估计人数有所下降。除布拉迪斯拉发和日利纳外,大部分地区首府的估计过早死亡人数水平相似。然而,当前的地缘政治局势和不断上涨的能源价格有可能使斯洛伐克颗粒物空气污染的最大来源--固体燃料的燃烧重新开始,从而使积极的趋势发生逆转。
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引用次数: 0
The lingering challenge: addressing vaccine hesitancy in a post-pandemic world. 挥之不去的挑战:在大流行后的世界中解决疫苗犹豫不决的问题。
IF 1.2 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-12-01 DOI: 10.21101/cejph.a7593
Ethan Ayaan Mir

Last time the world faced a deadly pandemic was the H1N1 Spanish flu in 1918, which affected almost one-third of the world's population (500 million people). Since then, almost 100 years later, we are now facing another pandemic of the SARS-CoV2 virus (COVID-19), which is still endemic to this day. As the technology evolved during those 100 years, an effective vaccine for COVID-19 was produced within only a year, a huge feat. But, unfortunately, due to its fast development, another force would arise limiting the impact of the vaccine: vaccine hesitancy and anti-vaxxers, which John Hopkins and the World Health Organization call the biggest current threat to global health. From politics to social media, it is clear that there has been a rapid spread of misinformation, resulting in hesitancy, especially from sociopolitically motivated people popularly referred to as anti-vaxxers. However, a second group of vaccine-hesitant people have also emerged, who are uneducated and remain undecided about vaccination mostly due to safety concerns. They come under the massive influence of anti-vaxxers and anti-vaccine propaganda through social media and politicians, which often make bold claims and huge headlines. To combat vaccine hesitancy, it is crucial that we debunk these conspiracy theories and misinformation that so many believe in, with factual, data-based information. Actively spreading correct information about the vaccines, such as disclosing the rigorous developmental processes and validation of safety data by the Food and Drug Administration (FDA), assurance for the unlikeliness of getting a lethal side effect along with tremendous health benefits, will encourage people for safe vaccination against COVID-19 and other potential infectious diseases in the future. This article discusses the role of anti-vaxxers and vaccine-hesitant groups, electronic social media, and politics in vaccine hesitancy among people. It describes the strategies to combat the roadblocks in the vaccination programmes and health benefits, offered by recent advances in scientific and technological developments.

上一次世界面临致命的大流行病是 1918 年的 H1N1 西班牙流感,它影响了全世界近三分之一的人口(5 亿人)。从那时起,将近 100 年后,我们又面临着 SARS-CoV2 病毒(COVID-19)的大流行,这种病毒至今仍在流行。在这 100 年中,随着技术的发展,COVID-19 的有效疫苗在短短一年内就被生产出来,这是一项巨大的成就。但不幸的是,由于疫苗的快速发展,另一股限制疫苗影响力的力量出现了:疫苗犹豫和反疫苗者,约翰-霍普金斯大学和世界卫生组织将其称为当前全球健康的最大威胁。从政治到社交媒体,很明显,错误信息迅速传播,导致人们犹豫不决,尤其是那些出于社会政治动机的人,即俗称的反疫苗者。然而,第二类对疫苗犹豫不决的人也出现了,他们没有受过教育,主要出于安全考虑而对疫苗接种犹豫不决。他们受到反疫苗接种者的巨大影响,并通过社交媒体和政客进行反疫苗宣传,而这些宣传往往会提出大胆的主张和巨大的标题。为了消除对疫苗的犹豫不决,我们必须用基于事实和数据的信息来揭穿这些让很多人深信不疑的阴谋论和错误信息。积极传播有关疫苗的正确信息,如披露严格的研发过程和食品药品管理局 (FDA) 对安全性数据的验证,保证不会出现致命的副作用以及巨大的健康益处,这将鼓励人们在未来安全接种疫苗,预防 COVID-19 和其他潜在的传染性疾病。本文讨论了反疫苗接种者和疫苗恐慌团体、电子社交媒体和政治在人们对疫苗犹豫不决中所起的作用。文章介绍了应对疫苗接种计划中的障碍的策略以及近期科技发展所带来的健康益处。
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引用次数: 0
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Central European journal of public health
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