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Long-term consequences of COVID-19 on mental and physical health in young adults. COVID-19 对青壮年身心健康的长期影响。
IF 1.1 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-01 DOI: 10.21101/cejph.a8118
Darina Falbová, Viktória Kovalčíková, Radoslav Beňuš, Lenka Vorobeľová

Objectives: This study investigates the impact of COVID-19 on various long-term psychological and physical symptoms in young adults from Slovakia.

Methods: We assessed 229 Slovak young adults aged 18 to 30 years. Probands were interviewed using standardised questionnaires. The relationship between COVID-19 and long-term health symptoms was determined using Pearson's chi-square test. The McNemar test was used to determine the differences in health symptoms before and after COVID-19 recovery.

Results: The statistically significant effect of COVID-19 after recovery on adverse cognitive health was only documented in women in the following symptoms: memory deterioration (p < 0.001), problems with concentration (p < 0.001), difficulty in handling tasks requiring thinking, planning and problem-solving (p < 0.001), and problems with finding the correct words in their expressions (p = 0.001). The prevalence of these symptoms was higher in women after the COVID-19 recovery than before. Participants also reported the most pronounced long-term changes in the following physiological symptoms: decreased physical fitness (p < 0.001 for women and men) and headaches (p < 0.001 for women). In addition, women menstrual cycle changes were reported significantly more frequently in women after COVID-19 recovery than before (p < 0.001). Furthermore, it was found that in addition to overcoming COVID-19, physical inactivity was also significantly associated with a deterioration in memory (p = 0.042), concentration problems (p = 0.041), and decreased physical fitness in women (p = 0.014). Smoking was associated with changes in the menstrual cycle (p = 0.002).

Conclusions: Significant effects of COVID-19 on mental and physical health were found. These effects demonstrate that COVID-19 has had a negative impact on the long-term health and quality of life of young adults.

目的:本研究调查了COVID-19对斯洛伐克年轻人各种长期心理和身体症状的影响。方法:我们评估了229名年龄在18至30岁之间的斯洛伐克年轻人。先证者采用标准化问卷进行访谈。使用Pearson卡方检验确定COVID-19与长期健康症状之间的关系。McNemar测试用于确定COVID-19恢复前后健康症状的差异。结果:COVID-19在康复后对不良认知健康的影响具有统计学意义,仅记录在以下症状的女性中:记忆力下降(p < 0.001),注意力问题(p < 0.001),处理需要思考、计划和解决问题的任务困难(p < 0.001),以及在表达中找到正确单词的问题(p = 0.001)。女性在COVID-19康复后出现这些症状的比例高于康复前。参与者还报告了以下生理症状的最显著的长期变化:身体健康下降(女性和男性p < 0.001)和头痛(女性p < 0.001)。此外,女性在COVID-19康复后月经周期变化的频率明显高于康复前(p < 0.001)。此外,研究发现,除了克服COVID-19之外,不运动还与女性记忆力下降(p = 0.042)、注意力集中问题(p = 0.041)和身体健康下降(p = 0.014)显著相关。吸烟与月经周期的改变有关(p = 0.002)。结论:新冠肺炎对患者身心健康均有显著影响。这些影响表明,COVID-19对年轻人的长期健康和生活质量产生了负面影响。
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引用次数: 0
Predictive parameters of cardiovascular risk in younger school-age children. 学龄儿童心血管风险的预测参数。
IF 1.1 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-01 DOI: 10.21101/cejph.a8376
Zlatana Sulinová, Erik Dorko, Kvetoslava Rimárová, Jana Diabelková, Martina Tejová, Andrea Houžvičková

Objectives: Overweight and obesity are important concerns for global health. They are characterized by excessive fat accumulation that can harm health. Childhood obesity has reached alarming levels around the world due to urbanization and changes in lifestyle. This trend highlights an urgent need for effective public health strategies to promote healthier lifestyles, prevent chronic diseases, and support the wellbeing of future generations. This study aimed to monitor the impact of the risk factors on blood pressure and lipid profile parameters.

Methods: Data were collected from 267 school-age children from Slovakia. The study assessed blood pressure using the sphygmomanometer technique, where systolic (SBP) and diastolic (DBP) blood pressure were measured in a seated position and repeated three times. The pulse rate was evaluated using Ruffier's physical fitness test. Anthropometric measurements included body weight, height, waist circumference, hip, and chest circumference, body mass index (BMI), and fat skinfolds measurement. The children's parents completed a comprehensive questionnaire. The data were statistically evaluated using IBM-SPSS version 19.

Results: Our analysis showed a statistically significant difference in SBP between obese and non-obese children (p < 0.001), but no significant differences for DBP and total cholesterol. Similar results were found between normal-weight and overweight children for SBP (p < 0.001), with overweight children showing higher SBP. No significant differences were noted for DBP or total cholesterol. Among children with "bad fitness", 57.9% had elevated SBP, compared to 37.86% with "good fitness" (p < 0.01). Additionally, 41.67% of children with bad fitness had elevated DBP, versus 23.05% in good fitness (p < 0.001). Significant differences in total cholesterol were also observed in these two groups (p < 0.05).

Conclusions: The results of this study confirm the importance of monitoring risk factors that significantly influence cardiovascular parameters.

目标:超重和肥胖是全球健康的重要问题。它们的特点是脂肪堆积过多,会损害健康。由于城市化和生活方式的改变,世界各地的儿童肥胖已达到令人担忧的水平。这一趋势突出表明,迫切需要制定有效的公共卫生战略,以促进更健康的生活方式,预防慢性疾病,并支持子孙后代的福祉。本研究旨在监测危险因素对血压和血脂参数的影响。方法:收集斯洛伐克267名学龄儿童的数据。该研究使用血压计技术评估血压,在坐姿中测量收缩压(SBP)和舒张压(DBP),并重复三次。采用Ruffier体质测试评估脉搏率。人体测量包括体重、身高、腰围、臀围、胸围、身体质量指数(BMI)和脂肪皮褶测量。孩子们的父母完成了一份全面的调查问卷。采用IBM-SPSS version 19对数据进行统计分析。结果:我们的分析显示肥胖和非肥胖儿童的收缩压差异有统计学意义(p < 0.001),但舒张压和总胆固醇无统计学差异。正常体重和超重儿童的收缩压相似(p < 0.001),超重儿童的收缩压更高。舒张压和总胆固醇没有显著差异。“体质差”组儿童收缩压升高57.9%,“体质好”组儿童收缩压升高37.86% (p < 0.01)。此外,41.67%健康状况不佳的儿童DBP升高,而健康状况良好的儿童DBP升高的比例为23.05% (p < 0.001)。两组总胆固醇水平差异有统计学意义(p < 0.05)。结论:本研究结果证实了监测显著影响心血管参数的危险因素的重要性。
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引用次数: 0
Birth outcomes of advanced maternal age pregnancies. 高龄产妇妊娠的出生结局。
IF 1.1 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-01 DOI: 10.21101/cejph.a8317
Jana Diabelková, Erik Dorko, Kvetoslava Rimárová, Peter Urdzík, Zlatana Sulinová, Andrea Houžvičková, Miroslav Kopecký

Objective: Pregnancy at advanced maternal age has become more common over the last decades. Therefore, the study aimed to describe the characteristics and maternal and perinatal outcomes of women giving birth at advanced maternal age and very advanced age.

Methods: We conducted a retrospective cohort study of 2,300 singleton births that occurred in 2020-2021 at the Department of Gynaecology and Obstetrics of the Louis Pasteur University Hospital in Košice. The control (age 20-34 years), advanced maternal age (35-39 years), and very advanced maternal age (≥ 40 years) groups included 1,851, 382, and 67 women, respectively. Exclusion criteria were multiple pregnancies, maternal age less than 20 years, smoking and alcohol use, foetal malformation and intrauterine foetal death, and birth weight of 500 grams or less. Data on mothers and newborn infants have been reported from the birth book and the reports on mothers at childbirth. The data were analysed using IBM SPSS Statistics 23.0.

Results: Our results confirmed statistically significant differences regarding the rate of preterm birth (p = 0.004), very preterm birth (p = 0.010), caesarean delivery rate (p < 0.001), very low birth weight (p = 0.027), extremely low birth weight (p = 0.001), and Apgar score at 5 minutes < 7 (p = 0.020) between newborns in the compared maternal age groups.

Conclusion: Advanced maternal age is a prognostic factor for poor pregnancy outcomes. Women of advanced maternal age are at higher risk of adverse obstetric and perinatal outcomes.

目的:在过去的几十年里,高龄妊娠变得越来越普遍。因此,本研究旨在描述高龄产妇和高龄产妇的特征和孕产妇及围产期结局。方法:我们对路易斯巴斯德大学医院Košice妇产科2020-2021年发生的2300例单胎分娩进行了回顾性队列研究。对照组(20 ~ 34岁)、高龄产妇组(35 ~ 39岁)和高龄产妇组(≥40岁)分别为1851例、382例和67例。排除标准为多胎妊娠、产妇年龄小于20岁、吸烟和饮酒、胎儿畸形和宫内胎儿死亡、出生体重小于或等于500克。关于母亲和新生儿的数据已从出生手册和关于分娩母亲的报告中得到报告。采用IBM SPSS Statistics 23.0对数据进行分析。结果:我们的研究结果证实了两组产妇在早产率(p = 0.004)、极早产率(p = 0.010)、剖宫产率(p < 0.001)、极低出生体重(p = 0.027)、极低出生体重(p = 0.001)和5分钟Apgar评分< 7 (p = 0.020)方面的差异具有统计学意义。结论:高龄产妇是不良妊娠结局的预后因素。高龄产妇发生不良产科和围产期结局的风险更高。
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引用次数: 0
Comparison of occupational diseases development during one decade in the Slovak and Czech Republic. 斯洛伐克和捷克共和国十年来职业病发展的比较。
IF 1.1 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-01 DOI: 10.21101/cejph.a7885
Erik Drabiščák, Erik Dorko, Kvetoslava Rimárová, Jozef Varga

Objectives: An occupational disease (OD) is a disorder or health condition which arises due to work related activities and tasks or is caused by work environment. The impact of ODs on medical and social system may be considered as a very important in relation to mortality, morbidity, and invalidity. The most common ODs in the European Union are musculoskeletal disorders (58% of all ODs in 2015). The aim of the study was to determine the differences in the incidence of occupational diseases between the Slovak Republic (SK) and the Czech Republic (CZ).

Methods: Data were obtained from the Health Statistics Yearbooks of the National Health Information Centre of the Slovak Republic and in CZ from the Institute of Health Information and Statistics of the Czech Republic. We worked with records from 2009 to 2019. The average incidence rates (aIR) per 100,000 labourers were calculated based on the number of workers in a given year. All data were calculated separately for SK and CZ, and for males and females. P < 0.05 was considered a significant value.

Results: In SK, the number of ODs diagnosed from 2009 to 2019 amounted to 2,351 cases in males and 1,605 cases in females. In CZ, the amount of ODs diagnosed from 2009 to 2019 reached 6,616 cases in males and 5,513 cases in females. In SK, from 2009 to 2019, the incidence of ODs decreased significantly from 7.3 to 4.8 cases per 100,000 labourers (rs = -0.76; p = 0.006). Diseases from one-sided excessive load were the most common ODs in SK (aIR = 7.6 ± 2.2) and in CZ (aIR = 8.2 ± 3.5), followed by ODs caused by vibration. Occupational diseases due to noise, vibrations and SiO2 inhalation were considerably more common among males. Diseases due to long-term excessive one-sided load, skin and infectious diseases were more prevalent in females. Occupational hearing damage due to noise was more frequent in SK and silicosis, asthma bronchiale, respiratory allergies, dermatoses, and infectious diseases were remarkably more frequent in CZ.

Conclusion: Regarding the main goal, we found a significantly higher aIR of ODs caused by noise in SK than in CZ. In CZ, there was a markedly higher presence of ODs caused by SiO2 inhalation, asthma and respiratory allergy, ODs of skin and infectious and parasitic ODs when compared to SK. In both countries different principles for discontinuance in work are applied when a risk factor occurs. It is necessary to enhance surveillance data and reporting of ODs and increase investments in occupational safety, health education and research for the future.

目的:职业病(OD)是由于与工作有关的活动和任务或由工作环境引起的一种失调或健康状况。ODs对医疗和社会系统的影响可能被认为是与死亡率、发病率和致残率有关的一个非常重要的因素。欧盟最常见的消耗药物是肌肉骨骼疾病(占2015年所有消耗药物的58%)。这项研究的目的是确定斯洛伐克共和国(SK)和捷克共和国(CZ)之间职业病发病率的差异。方法:数据来源于斯洛伐克共和国国家卫生信息中心的《卫生统计年鉴》和捷克共和国卫生信息与统计研究所的《CZ卫生统计年鉴》。我们处理了2009年至2019年的记录。每10万名劳动者的平均发病率(aIR)是根据某一年的劳动者人数计算的。所有数据分别计算SK和CZ,男性和女性。P < 0.05为差异有统计学意义。结果:在SK, 2009年至2019年诊断的ODs数量为男性2351例,女性1605例。在CZ, 2009年至2019年诊断出的ODs数量在男性中达到6616例,在女性中达到5513例。在SK,从2009年到2019年,耗氧物质的发病率从每10万名劳动者7.3例显著下降到4.8例(rs = -0.76;P = 0.006)。单侧过度负荷引起的ODs在SK (aIR = 7.6±2.2)和CZ (aIR = 8.2±3.5)中最为常见,其次是振动引起的ODs。噪音、振动和二氧化硅吸入引起的职业病在男性中更为常见。长期过度单侧负荷引起的疾病、皮肤病和传染病在女性中更为普遍。噪声引起的职业性听力损伤以SK多见,而矽肺病、支气管哮喘、呼吸道过敏、皮肤病和感染性疾病以CZ多见。结论:就主要目标而言,我们发现SK噪声引起的ODs的aIR明显高于CZ。在CZ,与SK相比,二氧化硅吸入、哮喘和呼吸道过敏、皮肤消耗物质以及传染性和寄生性消耗物质引起的消耗物质的存在明显更高。当危险因素发生时,两国采用不同的停止工作原则。有必要加强对消耗臭氧层物质的监测数据和报告,并为今后增加对职业安全、健康教育和研究的投资。
{"title":"Comparison of occupational diseases development during one decade in the Slovak and Czech Republic.","authors":"Erik Drabiščák, Erik Dorko, Kvetoslava Rimárová, Jozef Varga","doi":"10.21101/cejph.a7885","DOIUrl":"10.21101/cejph.a7885","url":null,"abstract":"<p><strong>Objectives: </strong>An occupational disease (OD) is a disorder or health condition which arises due to work related activities and tasks or is caused by work environment. The impact of ODs on medical and social system may be considered as a very important in relation to mortality, morbidity, and invalidity. The most common ODs in the European Union are musculoskeletal disorders (58% of all ODs in 2015). The aim of the study was to determine the differences in the incidence of occupational diseases between the Slovak Republic (SK) and the Czech Republic (CZ).</p><p><strong>Methods: </strong>Data were obtained from the Health Statistics Yearbooks of the National Health Information Centre of the Slovak Republic and in CZ from the Institute of Health Information and Statistics of the Czech Republic. We worked with records from 2009 to 2019. The average incidence rates (aIR) per 100,000 labourers were calculated based on the number of workers in a given year. All data were calculated separately for SK and CZ, and for males and females. P < 0.05 was considered a significant value.</p><p><strong>Results: </strong>In SK, the number of ODs diagnosed from 2009 to 2019 amounted to 2,351 cases in males and 1,605 cases in females. In CZ, the amount of ODs diagnosed from 2009 to 2019 reached 6,616 cases in males and 5,513 cases in females. In SK, from 2009 to 2019, the incidence of ODs decreased significantly from 7.3 to 4.8 cases per 100,000 labourers (rs = -0.76; p = 0.006). Diseases from one-sided excessive load were the most common ODs in SK (aIR = 7.6 ± 2.2) and in CZ (aIR = 8.2 ± 3.5), followed by ODs caused by vibration. Occupational diseases due to noise, vibrations and SiO<sub>2</sub> inhalation were considerably more common among males. Diseases due to long-term excessive one-sided load, skin and infectious diseases were more prevalent in females. Occupational hearing damage due to noise was more frequent in SK and silicosis, asthma bronchiale, respiratory allergies, dermatoses, and infectious diseases were remarkably more frequent in CZ.</p><p><strong>Conclusion: </strong>Regarding the main goal, we found a significantly higher aIR of ODs caused by noise in SK than in CZ. In CZ, there was a markedly higher presence of ODs caused by SiO<sub>2</sub> inhalation, asthma and respiratory allergy, ODs of skin and infectious and parasitic ODs when compared to SK. In both countries different principles for discontinuance in work are applied when a risk factor occurs. It is necessary to enhance surveillance data and reporting of ODs and increase investments in occupational safety, health education and research for the future.</p>","PeriodicalId":9823,"journal":{"name":"Central European journal of public health","volume":"32 Supplement","pages":"12-17"},"PeriodicalIF":1.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143001045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk of metabolic syndrome linked to tobacco smoking and caffeine consumption among Palestinian university students. 巴勒斯坦大学生患代谢综合征的风险与吸烟和摄入咖啡因有关。
IF 1.1 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-01 DOI: 10.21101/cejph.a7320
Ahmad Farhoud, Ibrahim Mahamid, Mohab Najjar, Anas Owda, Omar Safarini, Majdeddin MohammedAli, Ammar Thabaleh, Ahmed Mousa, Abdulraziq Zarour, Yazan Alhabil, Lubna Suadi, Zaher Nazzal, Basma Damiri

Objectives: The aim of the study was to determine the prevalence of metabolic syndrome (MetS) and its association with the use of tobacco smoking and caffeine consumption among Palestinian university students.

Methods: A cross-sectional study was conducted in 2020 among university students at An-Najah National University in the West Bank. MetS was diagnosed according to the National Cholesterol Education Programme. We employed adjusted multiple logistic regression models to address the association between MetS and tobacco smoking and caffeine consumption.

Results: The number of participants was 392. The findings revealed that 9.2% of the students met the diagnostic criteria for MetS, with a significantly higher prevalence in males (14.1%) than females (4.8%) (p = 0.001). The study highlighted various substance use rates among participants: 20.2% smoked cigarettes, 28.6% smoked waterpipes, 5.6% smoked e-cigarettes, and 39% consumed energy drinks. Coffee (83.9%) and black tea (84.7%) were also widely consumed. Mean values of triglyceride level (p = 0.006), systolic blood pressure (p < 0.001), and diastolic blood pressure (p = 0.016) were higher in cigarette smokers than nonsmokers. Energy drink consumers had higher levels of triglycerides than non-consumers (p = 0.015). Tea consumers had decreased mean values of fast blood sugar (p = 0.020) than non-users. The adjusted binary regression revealed that cigarette smokers were at greater risk of MetS (OR = 3.48, p = 0.009), and black tea consumers were less likely to have MetS (OR = 0.37, p = 0.032). Furthermore, increased BMI was associated with an increased risk of MetS (OR = 1.09, p = 0.008). Moreover, waterpipe smokers were at a higher risk of having high triglyceride levels (OR = 5.18, p = 0.027).

Conclusion: The study illustrates the health implications of tobacco and energy drink consumption on MetS among Palestinian university students, underlining waterpipe smoking as a pressing health concern linked to elevated triglycerides. These results clarify the MetS burden in Palestine and explore new risks and protective factors.

目的:本研究的目的是确定巴勒斯坦大学生中代谢综合征(MetS)的患病率及其与吸烟和咖啡因摄入的关系。方法:于2020年在西岸安纳杰国立大学的大学生中进行了一项横断面研究。MetS是根据国家胆固醇教育计划诊断的。我们采用调整后的多元逻辑回归模型来解决MetS与吸烟和咖啡因摄入之间的关系。结果:参与人数392人。结果显示,9.2%的学生符合met的诊断标准,其中男性的患病率(14.1%)明显高于女性(4.8%)(p = 0.001)。该研究强调了参与者的各种物质使用率:20.2%的人吸烟,28.6%的人抽水管,5.6%的人抽电子烟,39%的人喝能量饮料。咖啡(83.9%)和红茶(84.7%)也被广泛消费。吸烟者的甘油三酯水平(p = 0.006)、收缩压(p < 0.001)和舒张压(p = 0.016)平均值高于不吸烟者。能量饮料消费者的甘油三酯水平高于非消费者(p = 0.015)。饮茶者的空腹血糖平均值比不饮茶者低(p = 0.020)。调整后的二元回归显示,吸烟者患MetS的风险更高(OR = 3.48, p = 0.009),而红茶消费者患MetS的风险更低(OR = 0.37, p = 0.032)。此外,BMI增加与met风险增加相关(OR = 1.09, p = 0.008)。此外,水烟吸烟者甘油三酯水平高的风险更高(OR = 5.18, p = 0.027)。结论:该研究说明了烟草和能量饮料消费对巴勒斯坦大学生met的健康影响,强调了水烟吸烟是与甘油三酯升高有关的紧迫健康问题。这些结果阐明了巴勒斯坦的MetS负担,并探索了新的风险和保护因素。
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引用次数: 0
Association between polychlorinated biphenyls and circulatory immune markers: results from NHANES 1999-2004. 多氯联苯与循环免疫标记物之间的关系:1999-2004 年 NHANES 调查结果。
IF 1.1 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-01 DOI: 10.21101/cejph.a8056
Ma Yuzhu, Li Wei, Liu Ying, Chen Yong, Hu Kesheng

Objectives: Polychlorinated biphenyls (PCBs), a family of persistent toxic and organic environmental pollutants, were associated with multiple organ damages in humans once accumulating. However, association between PCBs exposure and circulatory immune markers were not clear.

Methods: Data was collected from participants enrolled in the National Health and Nutrition Examination Survey in 1999-2004. PCBs were categorized by latent class analysis (LCA). Weighted quantile sum (WQS) regression was used to investigate effects of PCBs exposure on circulatory immune markers including leukocyte counts, monocyte-lymphocyte ratio (MLR), neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), and systemic immune-inflammation index (SII).

Results: There were 3,109 participants included in the final analysis with blood PCBs levels presented as 3 classes. The high PCBs group had a higher rate of comorbidities. Leukocyte, lymphocyte and neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and system immune-inflammation index (SII) were significantly lower in the high PCBs group than in the low PCBs group (all p-values < 0.05). After adjusting for covariant variables, the low PCBs group was positively associated with SII (p = 0.021) and NLR (p = 0.006) in multivariate regression. Significantly negative correlations between PCBs classification and SII (β = -14.513, p = 0.047), and NLR (β = -0.035, p = 0.017) were found in WQS models. LBX028LA showed the most significant contribution in the associations between PCBs and SII, and LBX128LA contributed most significantly to associations with NLR.

Conclusion: Our study adds novel evidence that exposures to PCBs may be adversely associated with the circulatory immune markers, indicating the potential toxic effect of PCBs on the human immune system.

目的:多氯联苯(PCBs)是一种持久性有毒有机环境污染物,一旦积累会对人体造成多器官损害。然而,多氯联苯暴露与循环免疫标志物之间的关系尚不清楚。方法:收集1999-2004年全国健康与营养调查参与者的数据。采用潜类分析(LCA)对多氯联苯进行分类。采用加权分位数和(WQS)回归研究多氯联苯暴露对循环免疫标志物的影响,包括白细胞计数、单核细胞-淋巴细胞比率(MLR)、中性粒细胞-淋巴细胞比率(NLR)、血小板-淋巴细胞比率(PLR)和全身免疫-炎症指数(SII)。结果:3109名参与者纳入最终分析,血液中多氯联苯水平分为3类。高多氯联苯组的合并症发生率较高。高PCBs组白细胞、淋巴细胞、中性粒细胞与淋巴细胞比值(NLR)、血小板与淋巴细胞比值(PLR)和系统免疫炎症指数(SII)显著低于低PCBs组(p值均< 0.05)。在调整协变变量后,多氯联苯低组在多变量回归中与SII (p = 0.021)和NLR (p = 0.006)呈正相关。在WQS模型中,pcb分类与SII呈显著负相关(β = -14.513, p = 0.047), NLR呈显著负相关(β = -0.035, p = 0.017)。LBX028LA对多氯联苯与SII的关联贡献最大,LBX128LA对NLR的关联贡献最大。结论:我们的研究增加了新的证据,表明多氯联苯暴露可能与循环免疫标志物负相关,表明多氯联苯对人体免疫系统有潜在的毒性作用。
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引用次数: 0
Postpartum depression in Ukrainian refugee women who gave birth abroad after beginning of large-scale war. 大规模战争开始后,在国外生产的乌克兰难民妇女的产后抑郁症。
IF 1.1 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-01 DOI: 10.21101/cejph.a8003
Olena Kostiuk, Yelyzaveta Shunko, Roma Jusiene, Rima Breidokiene, Violeta Drejeriene, Sigita Lesinkiene, Arunas Valiulis

Objectives: The Russian military aggression against Ukraine in February 2022 became the cause of the biggest humanitarian crisis. Postpartum depression (PPD) is a type of mood disorder of pregnant and postpartum women. It was earlier reported that depression of pregnant women is increased in a combat zone, while effects of war on pregnant refugee and displaced women are less studied. The aim of the study was to determine the features of emotional state of temporarily displaced Ukrainian women who gave birth in Lithuania in spring-autumn 2022, and compare it with the state of Lithuanian women who were not directly affected by war.

Methods: The study was conducted by surveying a group of Ukrainian refugee women (UG) and a group of Lithuanian women (LG) who gave birth in maternity units of Lithuania, using Edinburgh Postpartum Depression Scale (EPDS), the questionnaire elaborated for evaluation of social and medical peculiarities of mother-child pair in early postpartum period as well as medical records of maternity unit.

Results: The average mean scores of EPDS in UG were significantly higher compared to LG; 42% of UG exceeded the threshold for the high risk of PPD (> 13). UG, who arrived in Lithuania during the war because of close relatives legally working in Lithuania, had lower EPDS scores to compare to UG who came from combat zones and who did not have close relatives.

Conclusions: Support of closest relatives and convenient surrounding is important for women's emotional state during the vulnerable period of maternity and especially during the crisis time.

目标:俄罗斯在2022年2月对乌克兰的军事侵略成为最大的人道主义危机的起因。产后抑郁症(PPD)是一种孕妇和产后妇女的情绪障碍。早些时候有报道称,在战区,孕妇的抑郁症增加,而战争对怀孕难民和流离失所妇女的影响研究较少。该研究的目的是确定2022年春秋期间在立陶宛分娩的临时流离失所的乌克兰妇女的情绪状态特征,并将其与未受战争直接影响的立陶宛妇女的状态进行比较。方法:采用爱丁堡产后抑郁量表(EPDS)对在立陶宛妇产科分娩的一组乌克兰难民妇女(UG)和一组立陶宛妇女(LG)进行调查,编制问卷,评价产后早期母子对的社会和医学特点以及妇产科的病历。结果:UG组EPDS平均评分显著高于LG组;42%的UG超过了PPD的高危阈值(bbb13)。由于近亲在立陶宛合法工作而在战争期间抵达立陶宛的UG,与来自战区且没有近亲的UG相比,其EPDS得分较低。结论:近亲属的支持和便利的周围环境对孕期脆弱期尤其是危机期妇女的情绪状态有重要作用。
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引用次数: 0
Acrylamide content in selected food products collected from Montenegrin market and health risk assessment. 从黑山市场收集的部分食品中的丙烯酰胺含量及健康风险评估。
IF 1.1 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-01 DOI: 10.21101/cejph.a8260
Dijana Đurović, Miljan Bigović, Ljubica Ivanović, Maja Blagojević, Amil Orahovac

Objectives: This study aimed to investigate the acrylamide exposure of different children and adult population groups (10-14 years, 15-17 years, 18-24 years, 25-44 years, 45-64 years, and 65-74 years) resulting from the consumption of potato chips and wheat-based bread from Montenegrin market and to evaluate it in terms of health risk.

Methods: The acrylamide content was monitored in 51 samples of bread and 20 samples of chips. The carcinogenic health risk in different population groups was assessed through the incremental lifetime cancer risk (CR) and total cancer risk (TCR).

Results: The average acrylamide content in potato chips and bread was calculated to be 238 μg/kg and 30 μg/kg, respectively. Acrylamide content in a tested sample met the criteria prescribed by Commission Regulation (EU) 2017/2158 in 98% of the tested samples of chips and 85% of bread samples. The carcinogenic health risk of acrylamide exposure for the investigated population groups is of concern. The values of CR for all the investigated groups were in the range of 10-6 < CR < 10-4 and the values of TCR were 10-5 order of magnitude, indicating a potential cancer risk.

Conclusion: The youngest population (10-14 years) was exposed to the highest cancer risk through the consumption of both, chips and bread. For the population of 10-14 years, 15-17 years, 25-44 years, 45-64 years, and 65-74 years, a higher risk of cancer was found due to the consumption of bread compared to the consumption of chips. Only the population aged 18-24 years was faced with a higher risk of cancer due to the consumption of chips compared to the consumption of bread.

目的:本研究旨在调查不同儿童和成人群体(10-14岁、15-17岁、18-24岁、25-44岁、45-64岁和65-74岁)因食用黑山市场的薯片和小麦面包而导致的丙烯酰胺暴露情况,并就其健康风险进行评估。方法:对51份面包和20份薯片进行丙烯酰胺含量检测。通过终生癌风险增量(CR)和总癌风险(TCR)对不同人群的致癌性健康风险进行评估。结果:计算出薯片和面包中丙烯酰胺的平均含量分别为238 μg/kg和30 μg/kg。测试样品中的丙烯酰胺含量在98%的薯条测试样品和85%的面包样品中符合欧盟委员会法规(EU) 2017/2158规定的标准。丙烯酰胺暴露对被调查人群的致癌健康风险令人关注。各调查组的CR值均在10-6 < CR < 10-4之间,TCR值为10-5个数量级,表明存在潜在的癌症风险。结论:最年轻的人群(10-14岁)因同时食用薯片和面包而面临最高的癌症风险。在10-14岁、15-17岁、25-44岁、45-64岁和65-74岁的人群中,吃面包比吃薯条患癌症的风险更高。只有18-24岁的人群因食用薯片而面临比食用面包更高的癌症风险。
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引用次数: 0
Socio-demographic and other factors contributing to excessive leisure screen time in preadolescent children. 导致青春期前儿童休闲屏幕时间过长的社会人口因素和其他因素。
IF 1.1 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-09-01 DOI: 10.21101/cejph.a7941
Kateřina Lukavská, Michal Božík, Niko Männikkö, Ondřej Hrabec, Michaela Slussareff, Jaroslav Vacek, Martina Píšová, Roman Gabrhelík

Objectives: Excessive screen use in early school age is associated with worsened health habits and negative child development in later age. We aimed to assess the time spent on modern and traditional screen-based devices and examine its associations with socio-demographic characteristics.

Methods: This population-based cross-sectional observation study was conducted in Czechia, Slovakia and Finland between April and June 2021. Participants (N = 1,915) were parents/caregivers of children attending elementary school grades 1 to 3, selected by stratified random sampling. Children's daily leisure screen time (LST) based on parental reports was the main outcome. Descriptive statistics, mean comparison and linear regression analysis were used for the analysis.

Results: The average daily LST was found to be as high as 3.5 hours and significantly associated with most socio-demographic variables. Eighty percent of children exceeded the threshold of two hours of LST per day, which was formerly introduced by the American Academy of Pediatrics. The most important predictor of LST in children was having their screen-based device(s) for their exclusive personal use (EPU). Linear regression with all predictors assessed together confirmed the significant effect of the screen-based devices' EPU, the child's sex and grade, the child's birth order and the parent's education, even when controlled for media parenting practices.

Conclusions: Given the widespread availability of smartphones for exclusive personal use among young children, the regulation of EPU and the reinforcement of effective media parenting practices, particularly in families with lower education and income, are critical public health strategies to mitigate the negative impact of excessive screen time on child development and overall well-being.

目的:学龄早期过度使用屏幕与健康习惯恶化和儿童日后的不良发展有关。我们旨在评估使用现代和传统屏幕设备的时间,并研究其与社会人口特征的关系:这项基于人口的横断面观察研究于 2021 年 4 月至 6 月间在捷克、斯洛伐克和芬兰进行。参与者(N = 1,915)是通过分层随机抽样选出的小学一至三年级儿童的父母/监护人。主要结果是根据家长报告的儿童每日休闲屏幕时间(LST)。分析采用了描述性统计、均值比较和线性回归分析等方法:结果发现,儿童的日均闲暇屏幕时间高达 3.5 小时,且与大多数社会人口变量有显著关联。80%的儿童都超过了美国儿科学会以前规定的每天两小时的LST阈值。预测儿童长时间使用电脑的最重要因素是他们的个人专用屏幕设备(EPU)。将所有预测因素一并评估的线性回归结果证实,即使在控制了媒体养育实践的情况下,屏幕设备的个人专用程度、儿童的性别和年级、儿童的出生顺序以及父母的教育程度也有显著影响:结论:鉴于智能手机在幼儿中广泛普及,供个人专用,因此,尤其是在教育程度和收入较低的家庭中,规范电子屏幕使用时间和加强有效的媒体养育方法是减轻过度使用屏幕时间对儿童发育和整体健康的负面影响的重要公共卫生策略。
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引用次数: 0
Course and complications of influenza A in seniors over 65 years of age. 65 岁以上老年人甲型流感的病程和并发症。
IF 1.1 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-09-01 DOI: 10.21101/cejph.a7877
Dalibor Sedláček, Robin Šín, Patrik Christian Cmorej, Miroslav Kubiska

Objectives: Influenza A and B viruses cause epidemics every year, with approximately 3-5 million serious cases and about 290,000 to 650,000 deaths worldwide. Most patients die from bacterial complications of influenza. The aim of our study was to describe the clinical pictures of influenza and the development of the complications in seniors over 65 years of age, who were treated in University Hospital Pilsen. The course of the disease and changes in laboratory parameters were evaluated with regard to the method of treatment performed.

Methods: A descriptive retrospective study was performed. Clinical and laboratory data of seniors with the diagnosis of influenza were extracted from electronic medical records and later analysed. The data were processed with Excel 2016 and Statistica.

Results: A collection of 261 seniors, of whom 218 were hospitalized and 43 treated in an outpatient setting, has been studied. Patients who later developed complications had elevated values of CRP, procalcitonin, urea, and creatinine. The antiviral drug oseltamivir was administered to 226 of 261 seniors. Forty-seven seniors (18.0%) died from influenza and its complications (severe pneumonia with acute respiratory insufficiency or heart failure).

Conclusions: The course of influenza in seniors was usually more severe and required hospitalization along with antiviral treatment. The mortality rate in the monitored group exceeded 18%. Annual timely vaccination, but also other preventive measures, and maybe considering other risk groups are methods to prevent severe or even fatal cases of influenza.

目的:甲型和乙型流感病毒每年都会引发流行病,全球约有 300-500 万例严重病例,约 29 万至 65 万人死亡。大多数患者死于流感的细菌并发症。我们的研究旨在描述在比尔森大学医院接受治疗的 65 岁以上老年人的流感临床表现和并发症发展情况。我们还根据所采用的治疗方法评估了病程和实验室参数的变化:方法:进行了一项描述性回顾研究。研究人员从电子病历中提取了确诊为流感的老年人的临床和实验室数据,随后进行了分析。数据使用 Excel 2016 和 Statistica 进行处理:研究对象包括 261 名老年人,其中 218 人住院治疗,43 人在门诊接受治疗。后来出现并发症的患者的 CRP、降钙素原、尿素和肌酐值升高。261 名老年人中有 226 人服用了抗病毒药物奥司他韦。47名老年人(18.0%)死于流感及其并发症(重症肺炎伴急性呼吸功能不全或心力衰竭):结论:老年人的流感病程通常更为严重,需要住院治疗和抗病毒治疗。监测组的死亡率超过 18%。每年及时接种疫苗,同时采取其他预防措施,并考虑其他高危人群,是预防严重甚至致命流感病例的方法。
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引用次数: 0
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Central European journal of public health
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