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Indexed Journal: What Does it Mean and Demand? 索引期刊:它的意义和需求?
Pub Date : 2017-12-16 DOI: 10.24915/aup.34.3-4.75
H. Donato
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引用次数: 0
Catheter-Associated Urinary Tract Infections in a Burn Unit: Epidemiological Study 烧伤病房导尿管相关尿路感染:流行病学研究
Pub Date : 2017-07-20 DOI: 10.24915/aup.34.1-2.4
L. Sepúlveda, M. Vaz, Í. Brito, C. Chaves, L. Cabral, J. Lima, Filipe Rodrigues
Introduction: Besides burn wound infections, burned patients are also more susceptible to other types of nosocomial infections. Catheter-associated urinary tract infections (CA-UTI) are one of the most common infections in this context, responsible for high morbidity, increased hospital stay and associated costs. The aim of this study was to characterize catheter-associated urinary tract infections in hospitalized burn patients and evaluate the frequency of microbiologic agents responsible for these infections. Material and Methods: Retrospective study, performed in a Burn Center (Coimbra Burns Unit) of a University Hospital (Centro Hospitalar e Universitario de Coimbra, Portugal – CHUC), based in the clinical data and urine cultures of burned patients who have performed at least once this exam between 1 January 2010 and 31 December 2014. Different variables such as date of infection, general characteristics of the population and the responsible pathogen were analyzed. Infections were further categorized taking into account the existence of previous episodes of CA-UTI, thereby defining primary infection, re- infection, relapse and over-infection. Results: Between January 2010 and December 2014, 213 CA-UTI were diagnosed in 143 patients. The most common uropathogens were E. coli (27.2%), Enterococcus faecalis (20.2%), Pseudomonas spp. (13.1%), Candida spp. (12.1%), Klebsiella spp. (10.8%) and Acinetobacter baumannii (9.9%). The most common microorganisms varied significantly depending on the gender of the patient. The CA-UTI analyzed corresponded to 143 primary infections, 44 reinfections, 17 relapses and nine over-infections. Relapse corresponded to 11% of infections in males and 5.7% in females and was significantly more frequent in infections due to Acinetobacter baumannii. Discussion/Conclusion: Catheter-associated urinary infections are common in intensive care units, particularly at Burn Units. The most common pathogens identified were similar to those reported in the literature. Pathogens responsible for polymicrobial infections were similar to those in monomicrobial infections, probably due to the short-term nature of urinary catheterization. Infections by Acinetobacter baumannii showed high susceptibility to relapse, which is probably related to its multi-drug resistance, common in this pathogen. The high relapse rate detected in males is probably related to the greater frequency of Acinetobacter baumannii infections in this gender. Candiduria was more frequent in the context of reinfection and over-infection, probably due to disruption of bacterial flora secondary to previous systemic antibiotics.
导读:除了烧伤创面感染外,烧伤患者也更容易发生其他类型的医院感染。导尿管相关性尿路感染(CA-UTI)是这种情况下最常见的感染之一,导致高发病率、住院时间和相关费用增加。本研究的目的是描述住院烧伤患者导尿管相关尿路感染的特征,并评估导致这些感染的微生物因子的频率。材料和方法:回顾性研究,在大学医院(Centro Hospitalar e Universitario de Coimbra, Portugal - CHUC)的烧伤中心(科英布拉烧伤科)进行,基于2010年1月1日至2014年12月31日期间至少进行过一次该检查的烧伤患者的临床数据和尿液培养。分析了感染日期、人群总体特征和病原等不同变量。考虑到既往CA-UTI发作的存在,进一步对感染进行分类,从而定义原发性感染、再感染、复发和过度感染。结果:2010年1月至2014年12月,143例患者中213例被诊断为CA-UTI。泌尿系致病菌以大肠杆菌(27.2%)、粪肠球菌(20.2%)、假单胞菌(13.1%)、念珠菌(12.1%)、克雷伯氏菌(10.8%)和鲍曼不动杆菌(9.9%)最为常见。最常见的微生物因患者的性别而有显著差异。CA-UTI分析对应143例原发感染,44例再感染,17例复发和9例过度感染。男性感染的复发率为11%,女性感染的复发率为5.7%,鲍曼不动杆菌感染的复发率明显更高。讨论/结论:导尿管相关性尿路感染常见于重症监护病房,尤其是烧伤科。鉴定出的最常见病原体与文献中报道的相似。导致多微生物感染的病原体与单微生物感染的病原体相似,可能是由于导尿的短期性质。鲍曼不动杆菌感染表现出较高的复发易感性,这可能与该病原体常见的多重耐药有关。在男性中检测到的高复发率可能与该性别中鲍曼不动杆菌感染的频率较高有关。念珠菌在再感染和过度感染的情况下更为常见,可能是由于以前全身性抗生素继发的细菌菌群破坏。
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引用次数: 0
Dilatação Endoscópica de Balão para Tratamento de Megaureter Obstrutivo Primário: Experiência de um Centro 内镜球囊扩张治疗原发性阻塞性巨静脉炎:中心经验
Pub Date : 2017-07-20 DOI: 10.24915/AUP.34.1-2.41
Sofia Morão, Vanda Pratas Vital, Dinorah Cardoso, Fátima Alves, F. C. Mota, J. Pascoal
Introduction: Congenital obstructive megaureter may be treated with endoscopic balloon dilatation, particularly in children under one year of age. We report our experience over a six year period. Patients and methods: All patients with diagnosis of primary obstructive megaureter (POM) treated with endoscopic balloon dilatation from 2009 to 2014 (6 years) were included. The diagnosis of POM was based on dilatation of the distal ureter greater than 7 mm, obstructive curve on MAG 3 diuretic renogram and absence of vesicoureteral reflux (VUR). After diagnosis, conservative management was maintained with antibiotic prophylaxis in all patients. The indications for surgery were a combination of clinical, ultrasonographic and renographic findings. Under general anesthesia and after retrograde ureteropielography, high pressure balloon dilation of the ureterovesical junction was performed under direct and fluoroscopic vision until the disappearance of the narrowed ring. A double-J catheter was positioned. Follow-up was performed with ultrasonography and diuretic renogram. The success of the intervention was defined by improvement of HUN (at least 2 grades). Results: A total of nine patients underwent this procedure on a single ureter, two girls and seven boys, with a mean age of 7. 6 months (range 1-14) at the intervention. Five were left sided and four were right sided. All patients had prenatal diagnosis of hydroureteronephrosis (HUN). No patients were lost to follow-up (average 46.7 months). They all had HUN greater than grade 3 and preoperative MAG3 diuretic renogram was obstructive in all cases.  Mean differential function of the affected kidney was 46.2% (range 40-53%). The main indication for surgical treatment was progressive HUN. All patients were treated endoscopically with no intraoperative complications. Ultrasound showed improvement of the HUN in six patients (66.7%). Three patients were reimplanted (33.3%). The mean differential renal function (DRF) after the procedure was 47.4% (range 41-53%). At the latest follow-up assessment, all patients remained asymptomatic. Discussion: Endoscopic balloon dilatation is a useful option in the management of POM requiring surgical intervention and may be considered first line treatment in small children.
简介:先天性梗阻性血压计可以用内镜下球囊扩张术治疗,特别是一岁以下的儿童。我们报告的是六年的经验。患者和方法:2009 - 2014年(6年)所有经内镜球囊扩张治疗原发性梗阻性计量器(POM)的患者。POM的诊断是基于输尿管远端扩张大于7mm, MAG - 3利尿肾图梗阻性曲线和无膀胱输尿管反流(VUR)。诊断后,所有患者均采用抗生素预防治疗。手术指征是结合临床、超声和肾造影结果。全麻下逆行输尿管造影后,在直视和透视下对输尿管膀胱连接处进行高压球囊扩张,直至狭窄环消失。放置双j型导管。随访采用超声及利尿肾图。干预的成功以HUN的改善(至少2个等级)来定义。结果:共有9例患者接受了单输尿管手术,2例女孩,7例男孩,平均年龄7岁。干预后6个月(范围1-14)。五个是左边的,四个是右边的。所有患者产前诊断为输尿管积水(HUN)。无患者失访(平均46.7个月)。所有患者的HUN均大于3级,术前MAG3利尿肾图均为梗阻性。受影响肾脏的平均差功能为46.2%(范围40-53%)。手术治疗的主要指征是进展性HUN。所有患者均行内镜治疗,无术中并发症。超声显示6例(66.7%)患者HUN改善。3例患者再植(33.3%)。术后平均差肾功能(DRF)为47.4%(范围41-53%)。在最近的随访评估中,所有患者仍无症状。讨论:内镜下球囊扩张术是治疗需要手术干预的POM的一种有效选择,可以考虑在儿童中进行一线治疗。
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引用次数: 0
Tumores Primários Superficiais de Alto Grau da Bexiga 高级别浅表原发性膀胱肿瘤
Pub Date : 2017-07-20 DOI: 10.24915/AUP.34.1-2.30
D. S. Pereira, F. Botelho, Carlos Silva, J. S. Silva
Purpose: We aimed to characterize the population with primary high-grade non muscle invasive bladder cancer followed in a Portuguese Central Hospital and simultaneously identify recurrence and progression rates and associated risk factors. Material and Methods: The analysis included 79 patients who were diagnosed with primary high-grade non muscle invasive bladder cancer on first transurethral resection between 2006 and 2010. Several variables were statistically analyzed to evaluate their prognostic importance. Results: With a median follow-up of 54 months, 19 patients (24.1%) recurred, four (5.1%) progressed to muscle-invasive disease and two (2.5%) underwent radical cystectomy. The most important prognostic factor of recurrence was the duration of intravesical bacillus Calmette-Guerin (BCG) treatment while the presence of carcinoma in situ was the most important prognostic factor of progression. Residual disease on second-look transurethral resection showed to reduce the recurrence-free-survival. Conclusion: In our population, recurrence and progression rates were much lower than those described in other studies. Residual disease on second-look transurethral resection is associated with decreased recurrence-free-survival while the presence of carcinoma in situ is related with higher risk of progression. The duration of treatment with BCG seems to reduce the risk of recurrence.
目的:我们旨在描述葡萄牙中心医院随访的原发性高级别非肌肉浸润性膀胱癌患者的特征,同时确定复发率和进展率以及相关危险因素。材料和方法:本研究纳入了2006年至2010年首次经尿道膀胱切除术诊断为原发性高级别非肌肉浸润性膀胱癌的79例患者。对几个变量进行统计分析以评估其预后重要性。结果:中位随访54个月,19例(24.1%)复发,4例(5.1%)进展为肌肉侵袭性疾病,2例(2.5%)行根治性膀胱切除术。最重要的预后因素是膀胱内卡介苗治疗的时间,而原位癌的存在是最重要的预后因素。经尿道二次检查切除后的残留病变可降低无复发生存率。结论:在我们的人群中,复发率和进展率远低于其他研究。经尿道二次检查切除的残留病变与无复发生存率降低相关,而原位癌的存在与更高的进展风险相关。卡介苗治疗的持续时间似乎可以降低复发的风险。
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引用次数: 0
Obras de Santa Engrácia
Pub Date : 2017-07-20 DOI: 10.24915/aup.34.1-2.56
Belmiro Parada
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引用次数: 0
Pediatric laparoscopic pieloplasty 儿童腹腔镜肾盂成形术
Pub Date : 2017-07-20 DOI: 10.24915/aup.34.1-2.3
Sofia Morão, Vanda Pratas Vital, A. V. Silva, Dinorah Cardoso, F. Alves, F. Mota, J. Pascoal
Introduction: Ureteropelvic junction obstruction (UPJO) is the most common congenital cause of upper urinary tract obstruction in children. Our objective is to report our experience concerning the first 20 laparoscopic pyeloplasties. Material and methods: Retrospective study including twenty children with diagnosis of UPJO that underwent laparoscopic pyeloplasty by a single surgeon, at our Hospital, between November 2010 and December 2014, with at least one year of follow-up. Success was defined as absence of conversion, resolution of symptoms and radiologic criteria improvement. Results: Median age at surgery was 9.5 years (range between 10 months and 17 years-old). Intrinsic obstruction was found in 7 cases, extrinsic obstruction in 12 cases and one case with both situations. Median operative time was 235 minutes (range between 165-275 minutes), with need for conversion in 2 cases (10%).  Median hospital stay was 2 days (range between 2-5 days. Four patients (20%) had early postoperative complications and two cases (10%) needed surgical revision during follow-up. Median follow-up time was 33 months (range between 12-60 months). In follow-up, all but two patients were asymptomatic. There was radiologic improvement of hydronephrosis in all patients but one, although he had non-obstructive pattern in renographic drainage. Conclusion: Our results are similar to those found in literature, with success rates comparable to open pyeloplasty with advantages of minimally invasive surgery.
导读:肾盂输尿管交界处梗阻(UPJO)是儿童上尿路梗阻最常见的先天性原因。我们的目的是报告前20例腹腔镜肾盂成形术的经验。材料和方法:回顾性研究包括2010年11月至2014年12月在我院由一名外科医生行腹腔镜肾盂成形术的20例诊断为UPJO的儿童,随访至少1年。成功的定义为没有转换,症状缓解和放射学标准改善。结果:手术年龄中位数为9.5岁(范围在10个月至17岁之间)。内源性梗阻7例,外源性梗阻12例,两种情况合并1例。中位手术时间为235分钟(范围在165-275分钟之间),2例(10%)需要转诊。住院时间中位数为2天(范围在2-5天之间)。4例(20%)患者出现术后早期并发症,2例(10%)患者在随访期间需要手术翻修。中位随访时间为33个月(12-60个月)。随访中,除2例患者外,其余均无症状。除1例患者外,所有患者肾积水的影像学表现均有改善,尽管他的肾造影引流呈非阻塞性模式。结论:我们的结果与文献中发现的结果相似,成功率与微创手术的开放性肾盂成形术相当。
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引用次数: 0
Tratamento de Fístulas Uro-Rectais Iatrogénicas em Tumores Pélvicos no Homem 男性盆腔肿瘤医源性尿直肠瘘的治疗
Pub Date : 2017-07-20 DOI: 10.24915/aup.34.1-2.7
F. Martins, David Martinho, L. C. Pinheiro, N. M. Martins, Luís Ferraz, Luís Xambre, L.O.P. Costa, T. Lopes
Introduction: Urorectal fistulas (URF) are a devastating complication of pelvic tumor treatment and a significant surgical challenge. Despite its increasing incidence associated with an increasing use of different forms of non-surgical treatment of pelvic tumours, urorectal fistula remains rare. Given the improbability of spontaneous closure, surgical correction becomes necessary in almost all cases. Despite the existence of various surgical techniques, rates of failure / recurrence are usually high, particularly in radiation fistulas. In this study the authors describe their experience in the treatment of URF resulting from pelvic tumor treatment. Methods: Between October 2008 and February 2015, 12 male patients were identified with URF treated in our institutions. A review of medical records of patients, including age, symptoms, comorbidity, diagnostic approach, type and fistula etiology, type of surgical reconstruction, follow-up and results was performed. Non-neoplastic / inflammatory fistula patients were excluded from the study. Results: We identified and treated 12 patients. One patient with fistula secondary to anterior resection of the rectum developed lymph node and liver metastases 4 months after the diagnosis of urorectal fistula and was consequently excluded from surgical treatment and study. The mean age of patients was 68 years (53-78). Nine patients developed URF after prostate cancer therapy: Two after low-dose brachytherapy combined with external beam radiation therapy; five after retropubic radical prostatectomy, with adjuvant radiation therapy in one; one after low-dose brachytherapy followed by transurethral resection of prostate; and one after high intensity focal ultrasound and radiation therapy. In two patients, the fistula resulted from surgical treatment of rectal carcinoma, associated with radiation therapy in one of them. In all patients with fecal and urinary diversion was performed by means of colostomy and suprapubic catheterization or urethral catheterization during the waiting period for surgical reconstruction. No spontaneous closure of URF occurred in any patient. Eleven patients underwent surgical reconstruction. Perineal approach was exclusively used in seven patients. In four patients, an abdominoperineal approach was employed. Effective fistula closure was reported in six patients after the first surgical attempt. Two patients required a second surgery, while one patient required three surgical procedures to achieve a successful result. Surgical failure occurred in two patients, which at present do not wish any additional reconstructive attempt. These two patients and one patient, in whom the reconstruction was effective, yet remain with colostomy. The mean follow-up was 25.5 months (3-75). Conclusion: URF are an uncommon but serious complication of treatment of pelvic tumors, usually associated with debilitating morbidity and loss of quality of life. Although a surgical reconstruction can be extremely di
导读:尿直肠瘘管(URF)是骨盆肿瘤治疗的一个破坏性并发症,也是一个重大的外科挑战。尽管泌尿直肠瘘的发病率随着盆腔肿瘤不同形式的非手术治疗的增加而增加,但它仍然很少见。由于不可能自发闭合,几乎所有病例都需要手术矫正。尽管存在各种手术技术,但失败率/复发率通常很高,特别是在放射瘘管中。在这项研究中,作者描述了他们治疗盆腔肿瘤引起的URF的经验。方法:2008年10月至2015年2月,12例男性患者在我院接受了URF治疗。对患者的医疗记录进行了审查,包括年龄、症状、合并症、诊断方法、类型和瘘管病因、手术重建类型、随访和结果。非肿瘤性/炎性瘘管患者被排除在研究之外。结果:我们发现并治疗了12例患者。1例直肠前切除术继发瘘管患者在诊断为尿直肠瘘管4个月后出现淋巴结和肝脏转移,因此被排除在手术治疗和研究之外。患者平均年龄为68岁(53 ~ 78岁)。前列腺癌治疗后发生URF 9例:低剂量近距离联合外束放射治疗2例;耻骨后根治性前列腺切除术5例,辅助放疗1例;1例为低剂量近距离治疗后经尿道前列腺切除术;一个是高强度局部超声和放射治疗后的。在2例患者中,瘘管是由直肠癌手术治疗引起的,其中1例伴有放射治疗。所有有粪尿分流的患者在手术重建等待期均行结肠造口加耻骨上置管或尿道置管。所有患者均未出现URF自发关闭。11例患者接受手术重建。会阴入路仅用于7例患者。在4例患者中,采用了腹部-会阴入路。在第一次手术尝试后,有6例患者报告了有效的瘘管闭合。两名患者需要第二次手术,而一名患者需要三次手术才能取得成功。手术失败发生2例,目前不希望任何额外的重建尝试。这两个病人和一个病人,重建是有效的,但仍保留结肠造口术。平均随访25.5个月(3-75)。结论:腔内瘘是盆腔肿瘤治疗中一种罕见但严重的并发症,通常伴有衰弱性发病率和生活质量下降。虽然手术重建可能非常困难,但在大多数情况下,通过会阴或腹会阴入路以及指征时使用插入组织都有可能获得成功的结果。
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引用次数: 0
Raro Caso de Leiomioma Paratesticular 罕见的证旁平滑肌瘤
Pub Date : 2017-07-20 DOI: 10.24915/aup.34.1-2.39
G. Brito, D. Ribeiro, Amanda Vanessa Demarchi, Angelo Maurílio Fosse Júnior, José A. Scheinkman
Introduction: Paratesticular tumors account for 2% of genitourinary neoplasms. They are benign neoplasms originating from the mesenchymal tissue, of slow and indolent growth, with no definite etiology, and can appear in any tissue composed of smooth muscle. Note the leiomyomas, which are considered a rare neoplasia in this location, so that their diagnosis is often confused with testicular tumors. Clinical Case: The authors present a case of a 56-year-old male patient admitted to the urology outpatient clinic with a large painless mass in the right testis of slow growth and a 3-year evolution. After further examination, he underwent right inguinal orchiectomy. The histopathological analysis and immunohistochemical profile of the surgical specimen showed a mesenchymal neoplasia compatible with atypical Paratesticular Leiomyoma, with borderline behavior and indolent growth. Discussion: This is a rare benign pathology whose etiology is frankly unknown and easily diagnosed as testicular origin. Therefore, this report sets out the objective of introducing this entity into medical knowledge in order to collaborate on future approaches.
简介:睾丸旁肿瘤占泌尿生殖系统肿瘤的2%。它们是起源于间质组织的良性肿瘤,生长缓慢,无明确病因,可出现在任何由平滑肌组成的组织中。注意平滑肌瘤,在这个部位被认为是一种罕见的肿瘤,因此它的诊断经常与睾丸肿瘤混淆。临床病例:作者提出一个病例56岁的男性患者入院泌尿科门诊,在右侧睾丸生长缓慢的无痛性肿块,3年的发展。在进一步检查后,他接受了右腹股沟睾丸切除术。手术标本的组织病理学分析和免疫组织化学特征显示间充质瘤与非典型睾丸旁平滑肌瘤相一致,具有边缘性行为和惰性生长。讨论:这是一种罕见的良性病理,其病因不明,很容易诊断为睾丸起源。因此,本报告提出了将这一实体纳入医学知识的目标,以便就今后的办法进行合作。
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引用次数: 1
Urethroplasty in Phalloplasty: Surgical Outcomes and Complications a Critical Review 尿道成形术在阴茎成形术中的应用:手术结果和并发症综述
Pub Date : 2017-07-20 DOI: 10.24915/AUP.34.1-2.8
A. Morgado, N. Tomada
Phalloplasty can be either performed as a penile reconstructive or phallic constructive procedure, mainly in penile trauma victims or female-to-male gender reassignment. After the introduction of the radial artery-based forearm free flap and with the further awareness of patient desire to void while standing, urethral reconstruction became a standard procedure and a main goal to attain in phalloplasty. Urethroplasty techniques can be broadly split in two main groups: as part of a tube-within-a-tube skin flap or as an independent other-than-skin graft. Urethral complications, such as fistula, stricture, or stones, are common and often recur after treatment. In this review, the main techniques of urethral reconstruction in phalloplasty are reviewed and compared. Urethral complications are also reviewed as well as their management.
阴茎成形术既可以作为阴茎重建手术,也可以作为阴茎重建手术,主要用于阴茎创伤患者或女性对男性的性别重置。在以桡动脉为基础的前臂游离皮瓣引入后,随着患者对站立时排空的愿望的进一步认识,尿道重建成为一种标准手术和阴茎成形术的主要目标。尿道成形术大致可分为两大类:作为管中管皮瓣的一部分或作为独立的非皮肤移植。尿道并发症,如瘘管、狭窄或结石,是常见的,并且经常在治疗后复发。本文就阴茎成形术中尿道重建的主要技术进行综述和比较。尿道并发症及其处理也将被回顾。
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引用次数: 0
Main Determinants of the Extent of Lymphadenectomy in Radical Cystectomy: A Study Based on Clinical Practice 根治性膀胱切除术中淋巴结切除范围的主要决定因素:基于临床实践的研究
Pub Date : 2017-05-26 DOI: 10.1016/S1569-9056(17)31926-7
L. Vale, F. B. L. Mendes, L. Pacheco-Figueiredo, T. Antunes-Lopes, João S. Silva, Carlos Silva
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引用次数: 0
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Acta Urológica Portuguesa
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