Advanced medical solutions rely on dependable biomechanical modeling. An enduring challenge in the constitutive modeling of soft tissue is delicately balancing model complexity, goodness-of-fit, and parameter identifiability, all of which impact the reliability of material behavior predictions under mechanical loading. It is established that biomechanical constitutive models, whether physically motivated or neural network derived, are typically sloppy from the information theory perspective. By analyzing the sensitivity matrix associated with posterior distributions of the constitutive parameters, a consistent pattern revealing the regularity in parameter combinations across experimental protocols characterizing tissue mechanical behavior and prior beliefs with varying levels of informativeness is discovered. The discovered pattern inspires to construct a sloppiness-based parameter hyperspace and proposes a model reduction program that performs model optimization by exploring four sub-hyperspaces. The proposed program offers a guide for effectively simplifying models while tightly ensuring parameter identifiability and prediction accuracy. Clear improvements are showcased to the brain tissue constitutive models discovered by neural networks and a physically motivated constitutive model of the human patellar tendon.
{"title":"Sloppiness Consistency in Biomechanical Models and Its Inspired Dual-Space Model Optimization","authors":"Jiabao Tang, Wenyang Liu, Yiqi Mao, Shujuan Hou","doi":"10.1002/apxr.202500002","DOIUrl":"10.1002/apxr.202500002","url":null,"abstract":"<p>Advanced medical solutions rely on dependable biomechanical modeling. An enduring challenge in the constitutive modeling of soft tissue is delicately balancing model complexity, goodness-of-fit, and parameter identifiability, all of which impact the reliability of material behavior predictions under mechanical loading. It is established that biomechanical constitutive models, whether physically motivated or neural network derived, are typically sloppy from the information theory perspective. By analyzing the sensitivity matrix associated with posterior distributions of the constitutive parameters, a consistent pattern revealing the regularity in parameter combinations across experimental protocols characterizing tissue mechanical behavior and prior beliefs with varying levels of informativeness is discovered. The discovered pattern inspires to construct a sloppiness-based parameter hyperspace and proposes a model reduction program that performs model optimization by exploring four sub-hyperspaces. The proposed program offers a guide for effectively simplifying models while tightly ensuring parameter identifiability and prediction accuracy. Clear improvements are showcased to the brain tissue constitutive models discovered by neural networks and a physically motivated constitutive model of the human patellar tendon.</p>","PeriodicalId":100035,"journal":{"name":"Advanced Physics Research","volume":"4 6","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/apxr.202500002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144273213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nitride-based Micro-light-emitting diode (Micro-LED) is now spreading into the field of display technology, which has been dominated by liquid crystal display (LCD), and organic LED (OLED). While high-power LEDs for solid-state lighting have been matured for many years, Micro-LEDs present significant challenges in manufacturing and characterization. This paper explores recent developments in Micro-LED display, providing an overview of current technologies and future possibilities in this field. This review focuses on the key technologies involved in manufacturing Micro-LEDs, including epitaxy and chip processing, mass transfer, driving, bonding, and detection technologies. It further summarizes the emerging applications of Micro-LEDs in full-color displays, flexible displays, augmented reality (AR), and virtual reality displays (VR).
{"title":"Recent Advances in Nitride-Based Micro-LEDs for Next-Generation Display","authors":"Jiahao Song, Jingjing Jiang, Minhua Li, Qianxi Zhou, Linyue Meng, Ke Sun, Siyuan Cui, Kuosheng Wen, Sheng Liu, Shengjun Zhou","doi":"10.1002/apxr.202400190","DOIUrl":"10.1002/apxr.202400190","url":null,"abstract":"<p>Nitride-based Micro-light-emitting diode (Micro-LED) is now spreading into the field of display technology, which has been dominated by liquid crystal display (LCD), and organic LED (OLED). While high-power LEDs for solid-state lighting have been matured for many years, Micro-LEDs present significant challenges in manufacturing and characterization. This paper explores recent developments in Micro-LED display, providing an overview of current technologies and future possibilities in this field. This review focuses on the key technologies involved in manufacturing Micro-LEDs, including epitaxy and chip processing, mass transfer, driving, bonding, and detection technologies. It further summarizes the emerging applications of Micro-LEDs in full-color displays, flexible displays, augmented reality (AR), and virtual reality displays (VR).</p>","PeriodicalId":100035,"journal":{"name":"Advanced Physics Research","volume":"4 6","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/apxr.202400190","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144273227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A Photonic Crystal Fiber sensor has been proposed, featuring an octagonal cladding and a hollow core, designed specifically for detecting kerosene adulteration. The sensor's performance is evaluated through numerical simulations across frequencies ranging from 1.0 to 3 THz. Kerosene is established into the innermost hole of the structure, and the strut size is adjusted to analyze the sensor's functionality at THz frequencies. At 2.2 THz, the sensor demonstrated impressive results, with a relative sensitivity of around 96.80%, an effective mode loss (EML) of 0.00667 cm−1, and a very low confinement loss of ≈6.78 × 10⁻8 dB m−1. This high sensitivity and precision make the proposed detector a promising tool for identifying kerosene adulteration, ensuring consumers receive high-quality petroleum products. Additionally, modern techniques like extrusion and 3D printing can be employed to manufacture the photonic crystal fiber indicator.
提出了一种具有八角形包层和空心芯的光子晶体光纤传感器,专门用于检测煤油掺假。该传感器的性能通过在1.0到3thz频率范围内的数值模拟进行评估。将煤油放入结构最内层的孔中,调整支柱尺寸以分析传感器在太赫兹频率下的功能。在2.2太赫兹下,传感器显示出令人印象深刻的结果,相对灵敏度约为96.80%,有效模式损耗(EML)为0.00667 cm−1,极低的约束损耗为≈6.78 × 10⁻8 dB m−1。这种高灵敏度和精度使所提出的检测器成为识别煤油掺假的有前途的工具,确保消费者获得高质量的石油产品。此外,可以采用挤压和3D打印等现代技术来制造光子晶体光纤指示器。
{"title":"A Sophisticated Terahertz Photonic Crystal Fiber Sensor Design for Highly Accurate Detection of Kerosene Mixtures","authors":"Mohammad Abdullah-Al-Shafi, Shuvo Sen","doi":"10.1002/apxr.202500025","DOIUrl":"10.1002/apxr.202500025","url":null,"abstract":"<p>A Photonic Crystal Fiber sensor has been proposed, featuring an octagonal cladding and a hollow core, designed specifically for detecting kerosene adulteration. The sensor's performance is evaluated through numerical simulations across frequencies ranging from 1.0 to 3 THz. Kerosene is established into the innermost hole of the structure, and the strut size is adjusted to analyze the sensor's functionality at THz frequencies. At 2.2 THz, the sensor demonstrated impressive results, with a relative sensitivity of around 96.80%, an effective mode loss (EML) of 0.00667 cm<sup>−1</sup>, and a very low confinement loss of ≈6.78 × 10<sup>⁻8</sup> dB m<sup>−1</sup>. This high sensitivity and precision make the proposed detector a promising tool for identifying kerosene adulteration, ensuring consumers receive high-quality petroleum products. Additionally, modern techniques like extrusion and 3D printing can be employed to manufacture the photonic crystal fiber indicator.</p>","PeriodicalId":100035,"journal":{"name":"Advanced Physics Research","volume":"4 9","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://advanced.onlinelibrary.wiley.com/doi/epdf/10.1002/apxr.202500025","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145057946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Melchi Chosenyah, Vuppu Vinay Pradeep, Vladimir Novikov, R. Sai Prasad Goud, Tatiana Murzina, Rajadurai Chandrasekar
Focused ion beam (FIB) milling with Ga-ions enabled early success in fabricating photonic cavities in organic crystals, advancing crystal photonic foundry. However, Ga-ion milling often causes contamination and amorphization. In contrast, Xe-ion plasma milling, with its inertness, faster milling, smoother finishes, and reduced sidewall damage, presents a promising alternative. This study introduces Xe-ion plasma milling for coumarin-153 dye crystals, to fabricate precise disc (DR1 and DR2) and ring resonators (RR1 and RR2). These resonators, crucial for sensors and photonic integrated circuits, support sustained light recirculation and enhanced optical signals, evident as resonant modes in photoluminescence spectra. Finite element analysis confirms the expected resonant optical modes and strong optical field localization near the resonators' outer boundaries, highlighting the FIB milling potential for advancing organic crystal photonics.
{"title":"Focused Xe-Ion Plasma Beam Milling of Coumarin-153 Single Crystals Into Photonic Cavities–Experimental and Theoretical Investigations","authors":"Melchi Chosenyah, Vuppu Vinay Pradeep, Vladimir Novikov, R. Sai Prasad Goud, Tatiana Murzina, Rajadurai Chandrasekar","doi":"10.1002/apxr.202500013","DOIUrl":"10.1002/apxr.202500013","url":null,"abstract":"<p>Focused ion beam (FIB) milling with Ga-ions enabled early success in fabricating photonic cavities in organic crystals, advancing <i>crystal photonic foundry</i>. However, Ga-ion milling often causes contamination and amorphization. In contrast, Xe-ion plasma milling, with its inertness, faster milling, smoother finishes, and reduced sidewall damage, presents a promising alternative. This study introduces Xe-ion plasma milling for coumarin-153 dye crystals, to fabricate precise disc (DR1 and DR2) and ring resonators (RR1 and RR2). These resonators, crucial for sensors and photonic integrated circuits, support sustained light recirculation and enhanced optical signals, evident as resonant modes in photoluminescence spectra. Finite element analysis confirms the expected resonant optical modes and strong optical field localization near the resonators' outer boundaries, highlighting the FIB milling potential for advancing organic crystal photonics.</p>","PeriodicalId":100035,"journal":{"name":"Advanced Physics Research","volume":"4 9","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://advanced.onlinelibrary.wiley.com/doi/epdf/10.1002/apxr.202500013","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145057763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Various quantum systems such as color centers, quantum dots, atoms, and molecules have demonstrated their capability for single-spin manipulation, which paves the way for new ideas and infinite possibilities in quantum information science. In review 2400146, Fei Gao, Chuancheng Jia, Xuefeng Guo and co-workers discuss in detail the progress and challenges of single-rotation manipulation and detection in the aforementioned quantum systems, and provide insights for future directions of research.