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Sloppiness Consistency in Biomechanical Models and Its Inspired Dual-Space Model Optimization 生物力学模型的马虎一致性及其启发的双空间模型优化
IF 2.8 Pub Date : 2025-04-28 DOI: 10.1002/apxr.202500002
Jiabao Tang, Wenyang Liu, Yiqi Mao, Shujuan Hou

Advanced medical solutions rely on dependable biomechanical modeling. An enduring challenge in the constitutive modeling of soft tissue is delicately balancing model complexity, goodness-of-fit, and parameter identifiability, all of which impact the reliability of material behavior predictions under mechanical loading. It is established that biomechanical constitutive models, whether physically motivated or neural network derived, are typically sloppy from the information theory perspective. By analyzing the sensitivity matrix associated with posterior distributions of the constitutive parameters, a consistent pattern revealing the regularity in parameter combinations across experimental protocols characterizing tissue mechanical behavior and prior beliefs with varying levels of informativeness is discovered. The discovered pattern inspires to construct a sloppiness-based parameter hyperspace and proposes a model reduction program that performs model optimization by exploring four sub-hyperspaces. The proposed program offers a guide for effectively simplifying models while tightly ensuring parameter identifiability and prediction accuracy. Clear improvements are showcased to the brain tissue constitutive models discovered by neural networks and a physically motivated constitutive model of the human patellar tendon.

先进的医疗解决方案依赖于可靠的生物力学建模。在软组织本构建模中,一个持久的挑战是微妙地平衡模型的复杂性、拟合优度和参数可识别性,所有这些都会影响材料在机械载荷下行为预测的可靠性。从信息论的角度来看,生物力学本构模型,无论是物理驱动的还是神经网络推导的,都是典型的草率的。通过分析与本构参数后验分布相关的灵敏度矩阵,发现了一个一致的模式,揭示了不同实验方案中表征组织力学行为和具有不同信息量的先验信念的参数组合的规律性。发现的模式启发我们构建了一个基于马虎度的参数超空间,并提出了一个模型约简程序,该程序通过探索四个子超空间来进行模型优化。该方案为有效简化模型提供了指导,同时严格保证了参数的可识别性和预测精度。通过神经网络发现的脑组织本构模型和人体髌骨肌腱的物理动机本构模型得到了明显的改进。
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引用次数: 0
Recent Advances in Nitride-Based Micro-LEDs for Next-Generation Display 下一代显示用氮基微型led的最新进展
IF 2.8 Pub Date : 2025-04-22 DOI: 10.1002/apxr.202400190
Jiahao Song, Jingjing Jiang, Minhua Li, Qianxi Zhou, Linyue Meng, Ke Sun, Siyuan Cui, Kuosheng Wen, Sheng Liu, Shengjun Zhou

Nitride-based Micro-light-emitting diode (Micro-LED) is now spreading into the field of display technology, which has been dominated by liquid crystal display (LCD), and organic LED (OLED). While high-power LEDs for solid-state lighting have been matured for many years, Micro-LEDs present significant challenges in manufacturing and characterization. This paper explores recent developments in Micro-LED display, providing an overview of current technologies and future possibilities in this field. This review focuses on the key technologies involved in manufacturing Micro-LEDs, including epitaxy and chip processing, mass transfer, driving, bonding, and detection technologies. It further summarizes the emerging applications of Micro-LEDs in full-color displays, flexible displays, augmented reality (AR), and virtual reality displays (VR).

氮基微发光二极管(Micro-LED)目前正在向液晶显示(LCD)和有机LED (OLED)主导的显示技术领域扩展。虽然用于固态照明的大功率led已经成熟多年,但micro - led在制造和表征方面面临着重大挑战。本文探讨了微型led显示屏的最新发展,概述了该领域的当前技术和未来可能性。本文综述了制造micro - led所涉及的关键技术,包括外延和芯片加工、传质、驱动、键合和检测技术。进一步总结了micro - led在全彩显示、柔性显示、增强现实(AR)和虚拟现实显示(VR)等领域的新兴应用。
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引用次数: 0
A Sophisticated Terahertz Photonic Crystal Fiber Sensor Design for Highly Accurate Detection of Kerosene Mixtures 用于煤油混合物高精度检测的精密太赫兹光子晶体光纤传感器设计
IF 2.8 Pub Date : 2025-04-21 DOI: 10.1002/apxr.202500025
Mohammad Abdullah-Al-Shafi, Shuvo Sen

A Photonic Crystal Fiber sensor has been proposed, featuring an octagonal cladding and a hollow core, designed specifically for detecting kerosene adulteration. The sensor's performance is evaluated through numerical simulations across frequencies ranging from 1.0 to 3 THz. Kerosene is established into the innermost hole of the structure, and the strut size is adjusted to analyze the sensor's functionality at THz frequencies. At 2.2 THz, the sensor demonstrated impressive results, with a relative sensitivity of around 96.80%, an effective mode loss (EML) of 0.00667 cm−1, and a very low confinement loss of ≈6.78 × 10⁻8 dB m−1. This high sensitivity and precision make the proposed detector a promising tool for identifying kerosene adulteration, ensuring consumers receive high-quality petroleum products. Additionally, modern techniques like extrusion and 3D printing can be employed to manufacture the photonic crystal fiber indicator.

提出了一种具有八角形包层和空心芯的光子晶体光纤传感器,专门用于检测煤油掺假。该传感器的性能通过在1.0到3thz频率范围内的数值模拟进行评估。将煤油放入结构最内层的孔中,调整支柱尺寸以分析传感器在太赫兹频率下的功能。在2.2太赫兹下,传感器显示出令人印象深刻的结果,相对灵敏度约为96.80%,有效模式损耗(EML)为0.00667 cm−1,极低的约束损耗为≈6.78 × 10⁻8 dB m−1。这种高灵敏度和精度使所提出的检测器成为识别煤油掺假的有前途的工具,确保消费者获得高质量的石油产品。此外,可以采用挤压和3D打印等现代技术来制造光子晶体光纤指示器。
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引用次数: 0
Focused Xe-Ion Plasma Beam Milling of Coumarin-153 Single Crystals Into Photonic Cavities–Experimental and Theoretical Investigations 聚焦氙离子等离子体束铣削香豆素-153单晶进入光子腔的实验和理论研究
IF 2.8 Pub Date : 2025-04-17 DOI: 10.1002/apxr.202500013
Melchi Chosenyah, Vuppu Vinay Pradeep, Vladimir Novikov, R. Sai Prasad Goud, Tatiana Murzina, Rajadurai Chandrasekar

Focused ion beam (FIB) milling with Ga-ions enabled early success in fabricating photonic cavities in organic crystals, advancing crystal photonic foundry. However, Ga-ion milling often causes contamination and amorphization. In contrast, Xe-ion plasma milling, with its inertness, faster milling, smoother finishes, and reduced sidewall damage, presents a promising alternative. This study introduces Xe-ion plasma milling for coumarin-153 dye crystals, to fabricate precise disc (DR1 and DR2) and ring resonators (RR1 and RR2). These resonators, crucial for sensors and photonic integrated circuits, support sustained light recirculation and enhanced optical signals, evident as resonant modes in photoluminescence spectra. Finite element analysis confirms the expected resonant optical modes and strong optical field localization near the resonators' outer boundaries, highlighting the FIB milling potential for advancing organic crystal photonics.

聚焦离子束(FIB)与镓离子的铣削使在有机晶体中制造光子腔的早期成功,推进了晶体光子铸造。然而,镓离子铣削经常造成污染和非晶化。相比之下,氙离子等离子铣削具有惰性、铣削速度更快、光面更光滑、侧壁损伤更小等优点,是一种很有前途的选择。本研究介绍了香豆素-153染料晶体的氙离子等离子铣床,以制造精确的圆盘(DR1和DR2)和环形谐振器(RR1和RR2)。这些谐振器对传感器和光子集成电路至关重要,支持持续的光再循环和增强的光信号,在光致发光光谱中表现为谐振模式。有限元分析证实了预期的谐振光学模式和谐振器外边界附近的强光场定位,突出了FIB铣削在推进有机晶体光子学方面的潜力。
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引用次数: 0
Operation of Single-Spin Qubits: Recent Advances and Prospects (Adv. Phys. Res. 4/2025) 单自旋量子比特的操作:最新进展与展望(物理学报)。研究》4/2025)
IF 2.8 Pub Date : 2025-04-10 DOI: 10.1002/apxr.202570010
Zhizhuo Zhang, Jushang Ran, Fei Gao, Chuancheng Jia, Xuefeng Guo

Single-Spin Manipulation of Quantum Systems

Various quantum systems such as color centers, quantum dots, atoms, and molecules have demonstrated their capability for single-spin manipulation, which paves the way for new ideas and infinite possibilities in quantum information science. In review 2400146, Fei Gao, Chuancheng Jia, Xuefeng Guo and co-workers discuss in detail the progress and challenges of single-rotation manipulation and detection in the aforementioned quantum systems, and provide insights for future directions of research.

量子系统的单自旋操纵各种量子系统,如色心、量子点、原子和分子,已经证明了它们的单自旋操纵能力,这为量子信息科学的新思想和无限可能性铺平了道路。在review 2400146中,高飞、贾传成、郭雪峰等详细讨论了上述量子系统中单旋转操纵和检测的进展和挑战,并为未来的研究方向提供了见解。
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引用次数: 0
Issue Information (Adv. Phys. Res. 4/2025) 发行信息(物理广告)研究》4/2025)
IF 2.8 Pub Date : 2025-04-10 DOI: 10.1002/apxr.202570009
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引用次数: 0
A Field Guide to Non-Onsager Quantum Oscillations in Metals (Adv. Phys. Res. 4/2025) 金属中非稳态量子振荡的场导则(物理版)。研究》4/2025)
IF 2.8 Pub Date : 2025-04-10 DOI: 10.1002/apxr.202570008
Valentin Leeb, Nico Huber, Christian Pfleiderer, Johannes Knolle, Marc A. Wilde

Quantum Oscillation Measurement

The circular motion of electrons in a magnetic field can be visualized in a Teltron tube. Electrons in metals behave in a similar way, leading to characteristic oscillations of observables. In review 2400134, Johannes Knolle and co-workers explain how they found new oscillations due to nonlinear couplings between multiple electron orbits. Cover image by Criss Hohmann (MCQST).

量子振荡测量电子在磁场中的圆周运动可以在电控管中可视化。金属中的电子以类似的方式运动,导致可观察到的特征振荡。在评论2400134中,Johannes Knolle和同事解释了他们是如何发现由于多个电子轨道之间的非线性耦合而产生的新振荡的。封面图片由克里斯·霍曼(MCQST)。
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引用次数: 0
Advanced Nanoscale Functionalities for Water and Energy Technologies 水和能源技术的先进纳米功能
IF 2.8 Pub Date : 2025-03-24 DOI: 10.1002/apxr.202400195
Zhi Xu, Nan Wu, Soufiane Abdelghani-Idrissi, Corentin Trégouët, Javier Perez-Carvajal, Annie Colin, Ming Ma, Antoine Niguès, Alessandro Siria

Nanofluidics, the study of fluid behaviors under nanoscale confinement, is driving transformative innovations in water and energy technologies. This rapidly evolving field leverages unique physical and chemical phenomena such as enhanced ion transport and tunable fluid interactions, enabling breakthrough advancements in critical applications. This review provides a comprehensive overview of theoretical frameworks and technological innovations facilitated by nanofluidics, highlighting its implications across diverse domains. Key applications include water treatment and desalination, where advanced nanostructured materials enable superior selectivity and efficiency in molecular and ionic separations. The principles of nanofluidics also offer new pathways for renewable energy generation, including harvesting osmotic energy and optimizing energy storage systems. Additionally, the integration of nanofluidics into carbon dioxide capture and utilization processes has opened new horizons for addressing climate change by enhancing reaction efficiencies and facilitating sustainable resource cycles. By bridging fundamental nanoscale science with innovative applications, nanofluidics presents a transformative approach for addressing global challenges in water security, sustainable energy, and environmental management. The review concludes by discussing scaling challenges, interdisciplinary opportunities, and the promising future directions of nanofluidic technologies for sustainable development.

纳米流体学,研究纳米尺度约束下的流体行为,正在推动水和能源技术的变革性创新。这一快速发展的领域利用了独特的物理和化学现象,如增强的离子传输和可调节的流体相互作用,从而在关键应用中取得突破性进展。这篇综述提供了纳米流体的理论框架和技术创新的全面概述,突出了其在不同领域的影响。关键应用包括水处理和海水淡化,其中先进的纳米结构材料在分子和离子分离方面具有卓越的选择性和效率。纳米流体的原理也为可再生能源的产生提供了新的途径,包括收集渗透能和优化储能系统。此外,将纳米流体整合到二氧化碳捕获和利用过程中,通过提高反应效率和促进可持续资源循环,为应对气候变化开辟了新的视野。通过将基础纳米科学与创新应用相结合,纳米流体为解决水安全、可持续能源和环境管理方面的全球挑战提供了一种变革性的方法。综述最后讨论了纳米流体技术在可持续发展中的规模挑战、跨学科机遇和未来发展方向。
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引用次数: 0
Strategies for Reducing Operating Voltage of Ferroelectric Hafnia by Decreasing Coercive Field and Film Thickness 通过减小矫顽力场和薄膜厚度来降低铁电铪合金工作电压的策略
IF 2.8 Pub Date : 2025-03-24 DOI: 10.1002/apxr.202400194
Dong In Han, Hyojun Choi, Dong Hyun Lee, Se Hyun Kim, Jaewook Lee, Intak Jeon, Chang Hwa Jung, Hanjin Lim, Min Hyuk Park

As the AI era advances, there has been increasing interest in the next-generation memory capable of low-power operation as well as high performance. HfO₂-based ferroelectric random-access memory (FeRAM) has been extensively studied for its simple structure similar to that of dynamic random-access memory (DRAM) and high power efficiency. However, due to the limited endurance of HfO2 and the high coercive field (Ec) arising from its high energy barrier for polarization switching, the commercialization of the low-power FeRAM faces several challenges. To address these issues, this perspective reviews current scientific approaches and experimental advances aimed at achieving low voltage switching in ferroelectric HfO2 thin films by reducing either Ec or film thickness. Key strategies including controlling types and number of dopants in HfO2, decreasing free energy of the intermediate tetragonal phase, achieving metal-excess rhombohedral phase, controlling oxygen vacancy concentration, and enhancing domain wall motion are reviewed based on theory as well as experimental demonstrations. Especially, recent progress in achieving low voltage operation in ferroelectric HfO2 capacitors via sub-5 nm thickness scaling are highlighted. Overall, the importance of precise material and process control to overcome current technical limitations in device scalability and reliability is emphasized, casting an optimistic outlook on the future of ferroelectric memory technology.

随着人工智能时代的发展,人们对低功耗和高性能的下一代存储器越来越感兴趣。基于HfO₂的铁电随机存取存储器(FeRAM)因其结构简单,与动态随机存取存储器(DRAM)相似,且具有较高的功率效率而受到广泛的研究。然而,由于HfO2的寿命有限,以及其极化开关的高能量势垒产生的高矫顽场(Ec),低功率FeRAM的商业化面临着一些挑战。为了解决这些问题,本观点回顾了当前的科学方法和实验进展,旨在通过减少Ec或薄膜厚度来实现铁电HfO2薄膜的低压开关。从理论和实验两方面综述了控制HfO2中掺杂物的种类和数量、降低中间四方相的自由能、实现金属过量的菱面体相、控制氧空位浓度和增强畴壁运动等关键策略。特别强调了通过低于5nm的厚度缩放实现铁电HfO2电容器低压工作的最新进展。总体而言,强调了精确的材料和工艺控制对于克服当前设备可扩展性和可靠性方面的技术限制的重要性,并对铁电存储技术的未来进行了乐观的展望。
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引用次数: 0
Sensing Pico-Newton Plasmonic Forces and Jerks of LSPR Biochips Using Simple UV-Visible Spectroscopy 利用简单紫外可见光谱学检测LSPR生物芯片的皮牛顿等离子体力和激振
IF 2.8 Pub Date : 2025-03-22 DOI: 10.1002/apxr.202400205
Nikhil Bhalla

Localized surface plasmon resonances (LSPRs) involve the oscillation of free electrons, leading to the maximum absorption of light by nanostructures at a specific wavelength. This absorption generates an action force exerted by the light on the nanostructures, with a corresponding reaction force—equal in magnitude but opposite in direction—arising from the plasmonic resonances. Additionally, the optical force exerted by light on nanostructures results in jerks or changes in its reaction force over time as it interacts with light. Through mathematical modeling, the reaction forces and jerks on large-area LSPR chips are determined using basic absorbance and reflection measurements performed with UV-Visible spectroscopy on gold nanomushrooms. The system tested, immunoglobulin G (IgG) antibody and its complementary antibody complex, revealed forces of 6 and 6.26 pN respectively. These main findings and especially the equations for reaction force and jerk, enhance our understanding of absorbance and reflection spectra obtained from UV-Visible spectroscopy. The developed model can be applied to analyze light-induced forces experienced by micro/nano/bio material systems using simple UV-Visible spectroscopy techniques.

局部表面等离子体共振(LSPRs)涉及自由电子的振荡,导致纳米结构在特定波长上对光的最大吸收。这种吸收产生了光在纳米结构上施加的作用力,而等离子共振产生了相应的反作用力——大小相等,方向相反。此外,光对纳米结构施加的光力在与光相互作用时,会随着时间的推移导致其反作用力的变化。通过数学建模,利用紫外可见光谱对金纳米蘑菇进行基本吸光度和反射测量,确定了大面积LSPR芯片上的反作用力和推力。系统测试,免疫球蛋白G (IgG)抗体及其互补抗体复合物分别显示6和6.26 pN的力。这些主要发现,特别是反作用力和反作用方程,增强了我们对紫外可见光谱的吸收光谱和反射光谱的理解。所开发的模型可以应用于使用简单的紫外可见光谱技术分析微/纳米/生物材料系统所经历的光诱导力。
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引用次数: 0
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Advanced Physics Research
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