Advanced Sensor and Energy Materials最新文献

英文中文

Wearable electrochemical sensor for real-time sweat monitoring powered by Li–S battery: Rapid ion-electron transduction driven by high-entropy Prussian blue analogues 用于实时汗液监测的可穿戴电化学传感器，由锂-S 电池供电：高熵普鲁士蓝类似物驱动的快速离子-电子转换

Advanced Sensor and Energy Materials

Pub Date : 2025-03-18 DOI: 10.1016/j.asems.2025.100150

Zhong-Hui Sun , Qiu-Ling Huang , Zhan-Chao Li , Wei Zheng , Yan Mao , Dong-Xue Han , Gang Huang

The portable electrochemical sensors couple with high-energy density batteries lay the foundation for intelligent electronic devices capable of real-time and long-term monitoring of signals at the molecular level. Currently, high-entropy materials play a crucial role in advanced energy storage system and electroanalytical chemistry due to their powerful multi active centers and lattice strain fields. Herein, we propose high-entropy Prussian blue analogues (HE-PBA) as a bidirectional catalyst to reduce the activation energy of sulfur redox reaction, alleviate polysulfides shuttle, and inhibit lithium dendritic growth in Li–S battery. Furthermore, benefited from hierarchical HE-PBA with multiple redox active sites, superior ion-selective effect, high ionic/electrical conductivity and hydrophobicity, thus contributing to splendid ion-electron transducer capability as solid contact layer in wearable potentiometric electrochemical sensors. As a result, an advanced wearable electronic device integrates LSB as a power source with potentiometric electrochemical sensor unit equipped with ion selective electrode, enabling real-time monitoring of K⁺ concentration in sweat metabolite during outdoor exercise. In a word, this work demonstrates a tremendous potential of designing multifunctional electrode materials for advanced energy storage and electrochemical sensing applications through high entropy strategies.

便携式电化学传感器与高能量密度电池的结合，为能够实时和长期监测分子水平信号的智能电子设备奠定了基础。目前，高熵材料因其强大的多活性中心和晶格应变场，在先进的储能系统和电分析化学中发挥着至关重要的作用。在此，我们提出将高熵普鲁士蓝类似物（HE-PBA）作为一种双向催化剂，以降低硫氧化还原反应的活化能，缓解多硫化物穿梭，并抑制锂枝晶在锂-S 电池中的生长。此外，由于分层 HE-PBA 具有多个氧化还原活性位点、卓越的离子选择效应、高离子/电导率和疏水性，因此在可穿戴电位计电化学传感器中作为固体接触层具有出色的离子-电子转换能力。因此，一种先进的可穿戴电子设备将作为电源的 LSB 与配备离子选择电极的电位计电化学传感器单元集成在一起，实现了对户外运动时汗液代谢物中 K+ 浓度的实时监测。总之，这项工作展示了通过高熵策略设计多功能电极材料用于先进储能和电化学传感应用的巨大潜力。

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引用次数: 0

Mid-infrared integrated spectroscopic sensor based on chalcogenide glasses: Optical characterization and sensing applications 基于硫系玻璃的中红外集成光谱传感器：光学特性和传感应用

Advanced Sensor and Energy Materials

Pub Date : 2025-03-18 DOI: 10.1016/j.asems.2025.100149

S. Meziani , A. Hammouti , L. Bodiou , N. Lorrain , R. Chahal , A. Bénardais , R. Courson , J. Troles , C. Boussard-Plédel , V. Nazabal , J. Charrier

A mid-infrared (mid-IR) spectroscopic sensor is developed using a chalcogenide glasses (ChGs) platform with a broad transmission band. The ridge ChGs waveguides were patterned via standard i-line photolithography and reactive ion etching, following the deposition of guiding and confinement layers through RF magnetron sputtering. The waveguides exhibit a wide transparency range from λ = 3.94–8.95 μm, with minimum propagation losses value of 2.5 dB/cm at λ = 7.58 μm. To validate the feasibility of the suggested sensor, a spectroscopic gas sensing experiment was performed using CO₂, resulting in an estimated limit of detection (LoD) of 1.16%v at λ = 4.28 μm, achieved with an external confinement factor Γ of 6.5%. Additionally, liquid sensing experiment was carried out using isopropanol, obtaining a LoD of 300 ppmv at λ = 7.25 μm.

采用宽频带硫系玻璃（ChGs）平台，研制了一种中红外光谱传感器。在射频磁控溅射沉积引导层和约束层之后，采用标准的i线光刻和反应离子刻蚀技术对脊状ChGs波导进行了图形化处理。该波导在λ = 3.94 ~ 8.95 μm范围内具有较宽的透明度，在λ = 7.58 μm处传输损耗最小，为2.5 dB/cm。为了验证该传感器的可行性，利用CO2进行了光谱气体传感实验，在λ = 4.28 μm时，估计的检测限（LoD）为1.16%v，外部约束因子Γ为6.5%。利用异丙醇进行了液体传感实验，在λ = 7.25 μm处测得的LoD为300 ppmv。

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引用次数: 0

Corrigendum to “Needle−tip effect promoted flexible electrochemical sensor for detecting chloride ions in food by in−situ deposited silver dendrimers” [Adv Sensor Energy Mater 3 (2024) 100100] “针尖效应促进的柔性电化学传感器用于原位沉积银树突物检测食品中的氯离子”的勘误表[Adv传感器能量物质3 (2024)100100]

Advanced Sensor and Energy Materials

Pub Date : 2025-03-10 DOI: 10.1016/j.asems.2024.100130

Huang Dai , Huilin Hu , Zhiyong Gong , Jing Shu , Jiahua Wang , Xiaodan Liu , Fuwei Pi , Qiao Wang , Shuo Duan , Yingli Wang

引用次数: 0

Enhanced multienzyme-like and antibacterial activity by copper atomically dispersed into molybdenum disulfide for accelerated wound healing 铜原子分散到二硫化钼中加速伤口愈合，增强了多酶样和抗菌活性

Advanced Sensor and Energy Materials

Pub Date : 2025-03-08 DOI: 10.1016/j.asems.2025.100148

Jiahao Shen , Junli Liu , Yunxiao Yi , Chenhui He , Hengyu Liu , Linrong Shi , Jin Liu , Pingen Shi , Hui Liu , Xuanmeng He , Yi Feng , Xingjian Song , Shaowei Chen

Bacterial and viral infections have been a global challenge, exacerbated by rampant antibiotic overuse. It is thus of fundamental and technological significance to develop effective antibacterial agents. Herein, copper is atomically dispersed into a MoS₂ matrix via the chelation of ammonium tetrathiomolybdate [(NH₄)₂MoS₄]. Meticulous control of the copper content enables uniform atomic dispersion and optimizes active site accessibility, both critical factors for a range of catalytic activities that mimic native enzymes like peroxidase, superoxide dismutase and glutathione oxidase. Among the series, the Cu/MoS₂-3 sample, with a Cu:Mo molar ratio of ca. 0.3, exhibits the best activity, with a maximum rate of 14.3 × 10⁻¹⁸ M s^–¹ in the peroxidase-like reaction with H₂O₂ and rate constant of 2.56 × 10⁻³ s⁻¹ that are at least one order of magnitude greater than those of MoS₂. These unique properties endow the resultant Cu/MoS₂ composites with a remarkable antimicrobial activity. Experimentally, with the addition of 1 mM H₂O₂, 99% of Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli can be eliminated within 10 min by Cu/MoS₂ (50 μg/mL). Such a peroxidase-like activity of Cu/MoS₂ can facilitate wound healing and inflammation reduction in a Staphylococcus aureus infected wound model. Results from this study highlight the unique significance of atomic dispersion in the structural engineering of high-performance bactericidal agents for biomedical applications.

细菌和病毒感染一直是全球性的挑战，抗生素的过度使用加剧了这一挑战。因此，开发有效的抗菌药物具有重要的基础和技术意义。在这里，铜通过四硫钼酸铵[(NH4)2MoS4]的螯合作用被原子分散到MoS2基质中。对铜含量的精细控制可以实现均匀的原子分散和优化活性位点的可达性，这两个因素都是模拟天然酶（如过氧化物酶、超氧化物歧化酶和谷胱甘肽氧化酶）的催化活性的关键因素。其中Cu/MoS2-3样品表现出最好的活性，Cu:Mo摩尔比约为0.3，在与H2O2的类过氧化物酶反应中，最大速率为14.3 × 10−18 M s - 1，速率常数为2.56 × 10−3 s - 1，比MoS2的速率常数至少大一个数量级。这些独特的性质使Cu/MoS2复合材料具有显著的抗菌活性。实验表明，在加入1 mM H2O2的条件下，铜/MoS2 （50 μg/mL）在10 min内可杀灭99%的革兰氏阳性金黄色葡萄球菌和革兰氏阴性大肠杆菌。在金黄色葡萄球菌感染的伤口模型中，Cu/MoS2的过氧化物酶样活性可以促进伤口愈合和炎症减轻。这一研究结果突出了原子分散在高性能生物医学杀菌剂结构工程中的独特意义。

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引用次数: 0

Metal-bearing nanomaterials for oral antibacteria: Mechanisms and applications 含金属纳米口腔抗菌材料：机理与应用

Advanced Sensor and Energy Materials

Pub Date : 2025-03-03 DOI: 10.1016/j.asems.2025.100141

Ke Quan , Yuqing Zeng , Sijia Gao , Yanli Lei , Le Yang , Yibo Zhou , Lucky Poh Wah Goh , Zhihe Qing

The prevalent oral diseases, such as dental caries, chronic gingivitis, and periodontitis, which are primarily caused by pathogenic bacteria, pose significant public health risks and impose substantial economic burdens. However, conventional treatment strategies for oral pathogens rely on mechanical debridement and antibiotic treatment, which remain unsatisfactory and contribute to the emergence of antimicrobial resistance pathogens. The escalating crisis of antibiotic resistance and the intricate microbial communities in oral niches urgently demand innovative antimicrobial strategies that can overcome these issues. Metal-bearing nanomaterials (MBNs), as an integration of metallic components with other substances such as polymers or inorganic materials, have demonstrated improved antimicrobial effectiveness while mitigating the toxicity associated with pure metals in oral environments. This review provides an innovative overview of designing and utilizing MBNs for oral antimicrobial applications, bridging the gap between nanomaterial design and clinical dentistry needs while guiding the development of next-generation antimicrobials in the post-antibiotic era. Firstly, we categorize and elucidate the main antibacterial mechanisms of metallic components in MBNs. Furthermore, a comprehensive summary is provided on the up-to-date advancements in using MBNs for oral antibacterial purposes, highlighting the pivotal role of metals in enhancing antibacterial properties. Finally, we discuss the existing challenges and potential future developments to establish a theoretical foundation for ongoing progress and clinical approval.

主要由致病菌引起的常见口腔疾病，如龋齿、慢性牙龈炎和牙周炎，构成重大的公共卫生风险，并造成巨大的经济负担。然而，口腔病原体的传统治疗策略依赖于机械清创和抗生素治疗，这仍然不令人满意，并导致抗微生物药物耐药性病原体的出现。不断升级的抗生素耐药性危机和口腔生态位中复杂的微生物群落迫切需要能够克服这些问题的创新抗菌策略。含金属纳米材料（MBNs）作为金属成分与其他物质（如聚合物或无机材料）的整合物，已证明可以提高抗菌效果，同时减轻口腔环境中与纯金属相关的毒性。本文综述了设计和利用MBNs用于口腔抗菌应用的创新概述，弥合了纳米材料设计与临床牙科需求之间的差距，同时指导了后抗生素时代下一代抗菌药物的开发。首先，我们对MBNs中金属成分的主要抑菌机制进行了分类和阐述。此外，本文还全面总结了MBNs在口腔抗菌方面的最新进展，强调了金属在增强抗菌性能方面的关键作用。最后，我们讨论了现有的挑战和潜在的未来发展，为正在进行的进展和临床批准建立理论基础。

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引用次数: 0

Editorial: Recent approaches in biosensors and wearable sensors 社论：生物传感器和可穿戴传感器的最新进展

Advanced Sensor and Energy Materials

Pub Date : 2025-03-01 DOI: 10.1016/j.asems.2025.100143

Chengyi Xiong

引用次数: 0

Simple surface modification of poly(methyl methacrylate) microfluidic microplates for enhanced ultrasensitive multiplexed detection of infectious diseases 聚甲基丙烯酸甲酯微流控微孔板的简单表面修饰，增强了传染病的超灵敏多路检测

Advanced Sensor and Energy Materials

Pub Date : 2025-02-28 DOI: 10.1016/j.asems.2025.100142

Sharma T. Sanjay , Sapna Kannan , XiuJun Li

Novel strategies for the simultaneous and portable detection of multiple analytes are highly favorable for clinical diagnosis and healthcare. Conventional colorimetric enzyme-linked immunosorbent assay (ELISA) is a widely used laboratory technique for medical diagnostics, quality control, and research applications. However, nonspecific absorption of proteins may lead to a reduction of functional sites, resulting in high background and low sensitivity in ELISA. Herein, we report a simple method of functionalization of poly(methyl methacrylate) (PMMA) with polylysine to be used as the microfluidic microplate substrate for enhanced ELISA, enabling rapid, ultrasensitive, and multiplexed detection of infectious diseases. FTIR and fluorescence microscopy characterization confirmed high amine densities on polylysine-modified PMMA surface, resulting in high detection sensitivity of the colorimetric ELISA on the PMMA microdevice. The ultrasensitive polylysine-modified microplate can immobilize protein within 20 min and results of the assay can be viewed by the naked eye or scanned through a simple desktop scanner for quantitative analysis within 90 min. A sandwich-type immunoassay for the rapid and sensitive detection of immunoglobulin G (IgG), hepatitis B surface antigen (HBsAg), and hepatitis B core antigen (HBcAg) was demonstrated as a proof-of-concept for multiplexed detection. The limits of detection (LOD) of 200.0 pg/mL for IgG, 180.0 pg/mL for HBsAg, and 300.0 pg/mL for HBcAg were achieved, without any specialized equipment like a microplate reader. The surface-modified microchip exhibited about 10-fold higher sensitivity than traditional microplates. This surface-modified microplate has tremendous potential as a point-of-care multiplexed testing platform for many applications ranging from clinical diagnosis to environmental monitoring, particularly in resource-limited settings.

同时便携式检测多种分析物的新策略对临床诊断和医疗保健非常有利。传统的比色酶联免疫吸附测定（ELISA）是一种广泛应用于医学诊断、质量控制和研究的实验室技术。然而，蛋白质的非特异性吸收可能导致功能位点的减少，导致ELISA的高背景和低灵敏度。在此，我们报告了一种用聚赖氨酸功能化聚甲基丙烯酸甲酯（PMMA）的简单方法，作为微流控微孔板底物，用于增强ELISA，实现快速、超灵敏和多路检测传染病。FTIR和荧光显微镜表征证实，聚赖氨酸修饰的PMMA表面具有较高的胺密度，使得比色ELISA在PMMA微装置上具有较高的检测灵敏度。超灵敏的聚赖氨酸修饰的微孔板可在20分钟内固定蛋白，检测结果可在90分钟内肉眼观察或通过简单的台式扫描仪扫描进行定量分析。用于快速灵敏检测免疫球蛋白G (IgG)，乙型肝炎表面抗原（HBsAg）和乙型肝炎核心抗原（HBcAg）的三明治型免疫分析法被证明是一种多路检测的概念验证。IgG的检出限（LOD）为200.0 pg/mL， HBsAg为180.0 pg/mL， HBcAg为300.0 pg/mL，无需任何专用设备，如微孔板阅读器。表面修饰的微芯片显示出比传统微孔板高10倍的灵敏度。这种表面修饰的微孔板具有巨大的潜力，可作为从临床诊断到环境监测等许多应用的即时多路测试平台，特别是在资源有限的环境中。

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引用次数: 0

3D-printed microneedles for sensing applications: Emerging topics and future trends 用于传感应用的3d打印微针：新兴主题和未来趋势

Advanced Sensor and Energy Materials

Pub Date : 2025-02-27 DOI: 10.1016/j.asems.2025.100139

Kelcilene B.R. Teodoro , Tamires S. Pereira , Ana Laura M.M. Alves , Francisco V. dos Santos , Fabrício A. dos Santos , Daniel S. Correa

3D-printed microneedles (MNs) have revolutionized the biomedical sector, enabling applications in aesthetic treatments, vaccine delivery, diagnostics, and real-time biomarker analysis. These minimally invasive structures advance the development of sensors and biosensors for diverse applications, including human, veterinary, agricultural, and environmental domains. Recent trends favor MNs made from polymers and nanomaterials over traditional metals, addressing challenges related to cost, biocompatibility, and scalability. In this context, this review explores recent advancements on different MNs-based sensors, fabricated by 3D printing, highlighting innovations, shortcomings and also pointing future opportunities to expand their applications in medical, agricultural and environmental domains. Initially, we discuss the general aspects of planning an efficient MN's design (encompassing possible types and required properties), as well as the choice of materials and manufacturing techniques for 3D printing polymeric MNs. Next, we examine the relationship between printing techniques, the manufactured MNs, and their integration with sensors, followed by examples of studies that explore this connection. Key innovations include the use of biodegradable resins, nanocomposites, artificial intelligence, and machine learning for design optimization. While biomedical applications dominate, we highlight significant opportunities for MNs in agriculture and environmental monitoring through tailored manufacturing approaches.

3d打印微针（MNs）彻底改变了生物医学领域，使其在美容治疗、疫苗输送、诊断和实时生物标志物分析方面的应用成为可能。这些微创结构促进了传感器和生物传感器的发展，用于各种应用，包括人类，兽医，农业和环境领域。最近的趋势倾向于由聚合物和纳米材料制成的纳米颗粒，而不是传统的金属，解决了与成本、生物相容性和可扩展性相关的挑战。在此背景下，本文探讨了3D打印制造的不同mns传感器的最新进展，突出了创新，缺点，并指出了未来扩大其在医疗，农业和环境领域应用的机会。首先，我们讨论了规划高效MN设计的一般方面（包括可能的类型和所需的性能），以及3D打印聚合物MN的材料选择和制造技术。接下来，我们将研究打印技术、制造的MNs及其与传感器的集成之间的关系，然后是探索这种联系的研究示例。关键创新包括使用可生物降解树脂、纳米复合材料、人工智能和机器学习进行设计优化。虽然生物医学应用占主导地位，但我们强调了通过定制制造方法在农业和环境监测方面的mnns的重大机会。

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引用次数: 0

Fluorescent graphene quantum dots: Properties regulation, sensing applications, and future prospects 荧光石墨烯量子点：特性调控、传感应用及未来展望

Advanced Sensor and Energy Materials

Pub Date : 2025-02-26 DOI: 10.1016/j.asems.2025.100140

Ru Wu , Yue Cao , Zixuan Chen , Jun-Jie Zhu

Graphene quantum dots (GQDs), as an emerging class of nascent carbon-based materials, demonstrate remarkable promise in fluorescence sensing applications. Those potentials stem from several factors, including their favorable photoluminescence (PL) characteristics, feasibility of surface functionalization, excellent biocompatibility, and low cytotoxicity. This review concentrates on the fundamental optical properties of GQDs, with specific reference to the manipulation of intrinsic characteristics both by heteroatom doping and surface/edge functionalization. These modifications permit the alteration of optical properties, thereby rendering GQDs more versatile for an array of applications. Subsequently, we then delve into the recent applications of GQDs in fluorescence sensing, encompassing both turn-off and turn-on mechanisms. Finally, it presents a systematic assessment of the current state of research on GQDs, along with discussions on challenges and prospects for expanding and improving their applications.

石墨烯量子点（GQDs）作为一类新兴的碳基材料，在荧光传感领域具有广阔的应用前景。这些潜力源于几个因素，包括其良好的光致发光（PL）特性，表面功能化的可行性，良好的生物相容性和低细胞毒性。本文综述了GQDs的基本光学性质，特别提到了杂原子掺杂和表面/边缘功能化对其内在特性的影响。这些修改允许改变光学性质，从而使GQDs在一系列应用中更加通用。随后，我们深入研究了GQDs在荧光传感中的最新应用，包括关闭和打开机制。最后，对GQDs的研究现状进行了系统评价，并讨论了GQDs在扩大和改进应用方面面临的挑战和前景。

引用次数: 0

Editorial: DNA and inorganic nanomaterials for sensors and energy 社论：用于传感器和能源的 DNA 和无机纳米材料

Advanced Sensor and Energy Materials

Pub Date : 2025-02-25 DOI: 10.1016/j.asems.2025.100138

Lihua Wang

引用次数: 0

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