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C1q receptors: Opportunities for selectively regulating protective and detrimental responses C1q受体:选择性调节保护性和有害反应的机会
Clinical Immunology Newsletter
Pub Date : 1997-12-01 DOI: 10.1016/S0197-1859(00)80026-6
A. Tenner
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引用次数: 2
C1q receptors: Opportunities for selectively regulating protective and detrimental responses C1q受体:选择性调节保护性和有害反应的机会
Clinical Immunology Newsletter
Pub Date : 1997-12-01 DOI: 10.1016/S0197-1859(00)80026-6
Andrea J. Tenner
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引用次数: 2
Complement inhibitors as therapeutic agents 补体抑制剂作为治疗剂
Clinical Immunology Newsletter
Pub Date : 1997-12-01 DOI: 10.1016/S0197-1859(00)80025-4
M. Liszewski, V. Subramanian, J. Atkinson
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引用次数: 4
Modulation of complement-mediated tissue injury by IVIG 补体介导的组织损伤的IVIG调节
Clinical Immunology Newsletter
Pub Date : 1997-12-01 DOI: 10.1016/S0197-1859(00)80024-2
M. Frank
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引用次数: 0
Index to volume 17 第17卷索引
Clinical Immunology Newsletter
Pub Date : 1997-12-01 DOI: 10.1016/S0197-1859(00)80027-8
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引用次数: 0
Natural killer cells in immune regulation 免疫调节中的自然杀伤细胞
Clinical Immunology Newsletter
Pub Date : 1997-10-01 DOI: 10.1016/S0197-1859(00)80020-5
Mary C. Nakamura

NK cells can influence the immune response through cytokine production and cytolysis of specific target cells. The identification of MHC-Class I specific-receptors on NK cells and their inhibitory effect on signal transduction has greatly enhanced our understanding of the mechanism of action of NK cells. NK cell function is dependent on the balance of inhibitory and activating signals received by the cell, from both direct interaction with target cells and from local immunoregulatory cytokines.

The recent progress in understanding the molecular basis of NK cell function has renewed considerable interest in the exact biological role of these cells. The role NK cells play in cancer, infectious disease, bone marrow transplantation, pregnancy and autoimmunity are currently active areas of research as well as further studies to define the molecular basis for NK activation and specificity.

NK细胞可以通过产生细胞因子和特异性靶细胞的细胞溶解来影响免疫应答。NK细胞上mhc - I类特异性受体的鉴定及其对信号转导的抑制作用，极大地增强了我们对NK细胞作用机制的认识。NK细胞的功能依赖于细胞接收的抑制和激活信号的平衡，这些信号来自与靶细胞的直接相互作用和局部免疫调节细胞因子。最近在了解NK细胞功能的分子基础方面取得的进展重新引起了对这些细胞确切生物学作用的相当大的兴趣。NK细胞在癌症、传染病、骨髓移植、妊娠和自身免疫中的作用是目前研究的活跃领域，同时还需要进一步研究确定NK活化和特异性的分子基础。
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引用次数: 0
Rapid, economical testing in the clinical laboratory: A new flow cytometry-based multiplex system 快速、经济的临床实验室检测:一种新的基于流式细胞术的多重检测系统
Clinical Immunology Newsletter
Pub Date : 1997-10-01 DOI: 10.1016/S0197-1859(00)80021-7
Ralph L. McDade, Michael D. Spain

Luminex Corp. has developed a multiplex assay system (FlowMetrix) that incorporates the most advanced digital signal processing technology into an established assay platform, enhancing its speed, economy, sensitivity, precision, and throughput. Microsphere-based assays are now multiplexed assays, capable of performing up to 64 discrete tests in a single tube from the same sample at the same time. The flow cytometer becomes an absolute measurement instrument, acquiring and analyzing the data generated by thousands of microspheres every second, and reporting the values in real time. With applications in routine immunoassay and advanced molecular diagnostics, this system should provide significant benefit to the clinical laboratory today and in the future.

Luminex公司开发了一种多路分析系统(FlowMetrix)，该系统将最先进的数字信号处理技术整合到已建立的分析平台中，提高了其速度，经济性，灵敏度，精度和吞吐量。基于微球的分析现在是多路分析，能够在同一时间从同一样品中在单个试管中执行多达64个离散测试。流式细胞仪成为一种绝对的测量仪器，每秒获取和分析数千个微球产生的数据，并实时报告数值。随着常规免疫分析和高级分子诊断的应用，该系统将为今天和未来的临床实验室提供显著的好处。
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引用次数: 4
Advances in peripheral blood stem cell transplantation 外周血干细胞移植研究进展
Clinical Immunology Newsletter
Pub Date : 1997-10-01 DOI: 10.1016/S0197-1859(00)80022-9
Heather Tapp , Luen Bik To , David Haylock
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引用次数: 0
Major histocompatibility class II associated antigen processing 主要组织相容性II类相关抗原加工
Clinical Immunology Newsletter
Pub Date : 1997-10-01 DOI: 10.1016/S0197-1859(00)80019-9
Daniel M. Eisenstein , Susan K. Pierce
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引用次数: 0
Human granulocytic ehrlichiosis 人粒细胞埃里希体病
Clinical Immunology Newsletter
Pub Date : 1997-10-01 DOI: 10.1016/S0197-1859(00)80018-7
Harold W. Horowitz, Gary P. Wormser
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引用次数: 4
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