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Clinical Characteristics and Influencing Factors of Postoperative Pain in Patients Undergoing Gastric Endoscopic Submucosal Dissection 胃内镜下粘膜下剥离术后疼痛的临床特点及影响因素
IF 3.3 Pub Date : 2025-07-25 DOI: 10.1002/hcs2.70024
Fen Deng, Liru Pan, Lei Tao, Xiaoyu Qiu, Bing Li, Jing Hao, Huihui Li, Zhenzhen Zhang, Weiwei Ding, Yingying Wang, Bo Ning
<div> <section> <h3> Background</h3> <p>To comprehensively analyze the clinical characteristics of patients who underwent gastric endoscopic submucosal dissection (ESD) and explore the incidence and influencing factors of postoperative pain.</p> </section> <section> <h3> Methods</h3> <p>The clinical data of patients who underwent gastric ESD at our center from 2009 to 2024 were retrospectively analyzed. Pain severity was assessed using a visual analogue scale, with a score ≥ 4 defined as postoperative pain. Based on the presence or absence of postoperative pain, patients were divided into a pain group and a control group. Independent factors influencing postoperative pain were identified using multivariate logistic regression analysis. To control for confounding bias, patients in the case and control groups were matched by sex and lesion size, and the matched participants were further analyzed using a conditional logistic regression model.</p> </section> <section> <h3> Results</h3> <p>In total, 993 patients were analyzed. The incidence of postoperative pain was 9.1% (95% confidence interval [CI], 7.3–11.1). In the univariate analysis, sex, operation duration, anesthesia method, intraoperative electrocoagulation, nasogastric tube placement, and postoperative vomiting were significantly associated with postoperative pain. Multivariate analysis identified eight independent factors: male sex (odds ratio [OR], 0.61; 95% CI, 0.37–0.97; <i>p</i> = 0.04), operation duration (OR, 1.29; 95% CI, 1.03–1.63; <i>p</i> = 0.02), protuberant lesions (OR, 0.43; 95% CI, 0.26–0.71; <i>p</i> < 0.01), antral lesions (OR, 1.84; 95% CI, 1.10–3.05; <i>p</i> = 0.01), intubation general anesthesia (OR, 0.40; 95% CI, 0.22–0.72; <i>p</i> = 0.002), intraoperative electrocoagulation (OR, 0.32; 95% CI, 0.19–0.55; <i>p</i> < 0.01), nasogastric tube placement (OR, 2.005; 95% CI, 1.12–3.57; <i>p</i> = 0.01), and postoperative vomiting (OR, 3.24; 95% CI, 1.40–7.47; <i>p</i> = 0.005). Conditional logistic regression analysis further identified diabetes mellitus (OR, 2.50; 95% CI, 1.03–6.06; <i>p</i> = 0.04).</p> </section> <section> <h3> Conclusion</h3> <p>Female sex, diabetes mellitus, concave-type lesions, lesions in the gastric antrum, non-intubation general anesthesia, absence of intraoperative electrocoagulation, prolonged operation duration, nasogastric tube placement, and postoperative vomiting were independent factors associated with moderate to severe pain after gastric ESD. For patients at increased risk of postoperative pain, appropriate prophylactic and therapeutic m
背景综合分析胃内镜下粘膜下剥离术(ESD)患者的临床特点,探讨术后疼痛的发生率及影响因素。方法回顾性分析2009 ~ 2024年我院行胃ESD手术患者的临床资料。使用视觉模拟量表评估疼痛严重程度,评分≥4分定义为术后疼痛。根据有无术后疼痛,将患者分为疼痛组和对照组。采用多因素logistic回归分析确定影响术后疼痛的独立因素。为了控制混杂偏倚,病例组和对照组的患者按性别和病变大小进行匹配,并使用条件逻辑回归模型对匹配的参与者进行进一步分析。结果共分析993例患者。术后疼痛发生率为9.1%(95%可信区间[CI], 7.3-11.1)。在单因素分析中,性别、手术时间、麻醉方式、术中电凝、鼻胃管放置和术后呕吐与术后疼痛显著相关。多因素分析确定了8个独立因素:男性(优势比[OR], 0.61, 95% CI, 0.37-0.97, p = 0.04),手术时间(OR, 1.29, 95% CI, 1.03-1.63, p = 0.02),突出病变(OR, 0.43, 95% CI, 0.26-0.71, p = 0.01),胃窦病变(OR, 1.84, 95% CI, 1.10-3.05, p = 0.01),插管全麻(OR, 0.40, 95% CI, 0.22-0.72, p = 0.002),术中电凝(OR, 0.32, 95% CI, 0.19-0.55, p < 0.01),鼻胃管放置(OR, 2.005, p = 0.04);95% ci, 1.12-3.57;p = 0.01)和术后呕吐(OR, 3.24; 95% CI, 1.40-7.47; p = 0.005)。条件logistic回归分析进一步确定了糖尿病(OR, 2.50; 95% CI, 1.03-6.06; p = 0.04)。结论女性、糖尿病、凹型病变、胃窦病变、非插管全麻、术中未电凝、手术时间延长、鼻胃管放置、术后呕吐是胃ESD术后中重度疼痛的独立影响因素。对于术后疼痛风险增高的患者,围手术期采取适当的预防和治疗措施可有效缓解胃ESD术后疼痛。
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引用次数: 0
Validation and Reliability Testing of the Yonsei Lifestyle Profile for Assessing Multifaceted Health Lifestyles 评估多方面健康生活方式的延世生活方式档案的验证和信度测试
IF 3.3 Pub Date : 2025-07-22 DOI: 10.1002/hcs2.70023
Young-Myoung Lim, Ah-Ram Kim, Seung-Ju Lim, Ji-Hyuk Park

Background

In this study, we aimed to validate and test the reliability of the Yonsei lifestyle profile (YLP) in assessing multifaceted health lifestyle levels in a study population from the United States.

Methods

The YLP-English version and health-promoting lifestyle profile II were administered to 100 individuals living in the United States. Concurrent validity was analyzed using Pearson's correlation coefficient, and discriminant validity was examined by comparing sex and age differences through t-tests and multiple variance analysis. Internal consistency was assessed using Cronbach's α for each sub-factor.

Results

The YLP-English Version demonstrated concurrent validity with the Health-Promoting Lifestyle Profile II, showing consistent correlations for the total score (0.3, p < 0.01) and frequency sub-factors (0.25–0.69, p < 0.01). Among the satisfaction sub-factors, only nutrition showed a weak negative correlation (−0.19, p < 0.01); all others were nonsignificant. Discriminant validity revealed no significant sex differences, but physical activity frequency varied across age groups. Internal consistency was high (Cronbach's α = 0.80–0.86).

Conclusion

In this study, we validated the YLP-English version as a reliable instrument for assessing health-related lifestyle behaviors. The YLP uniquely captures both lifestyle frequency and satisfaction, offering a comprehensive perspective on health behaviors. Although this tool is currently most applicable in population-level studies, future research should establish clinical thresholds to enhance its utility in individualized health assessments and interventions.

在这项研究中,我们旨在验证和测试延世生活方式概况(YLP)在评估美国研究人群的多方面健康生活方式水平方面的可靠性。方法对100名生活在美国的个人进行ylp -英文版和健康促进生活方式量表II。采用Pearson相关系数分析并发效度,采用t检验和多元方差分析比较性别和年龄差异检验区分效度。采用Cronbach’s α对各子因子进行内部一致性评价。结果ylp -英文版与健康促进生活方式量表II具有同步效度,总分(0.3,p < 0.01)和频率子因子(0.25-0.69,p < 0.01)具有一致的相关性。在满意度子因子中,只有营养与满意度呈弱负相关(- 0.19,p < 0.01);其他的都不显著。判别效度显示性别差异不显著,但不同年龄组的运动频率存在差异。内部一致性高(Cronbach’s α = 0.80-0.86)。在本研究中,我们验证了ylp -英文版是评估健康相关生活方式行为的可靠工具。YLP独特地捕捉了生活方式的频率和满意度,提供了健康行为的全面视角。虽然这一工具目前最适用于人群水平的研究,但未来的研究应建立临床阈值,以提高其在个性化健康评估和干预方面的效用。
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引用次数: 0
Noninvasive Breast Cancer Screening Strategies Supported by AI-Based Technologies in Resource-Limited Settings: Is It the Best Opportunity to Strengthen Women's Preferences, Values and Acceptability? 在资源有限的环境下,人工智能技术支持的无创乳腺癌筛查策略:这是增强女性偏好、价值观和可接受性的最佳机会吗?
IF 3.3 Pub Date : 2025-07-22 DOI: 10.1002/hcs2.70025
Wolmark Xiques-Molina, Ivan David Lozada-Martinez, Ornella Fiorillo-Moreno, Alexis Narvaez-Rojas
<p>Breast cancer is the leading cause of cancer-related mortality in women globally, with its incidence continuing to rise, particularly in low- and middle-income countries, presenting a significant public health challenge worldwide [<span>1</span>]. According to data from the Institute for Health Metrics and Evaluation (IHME) and the World Health Organization (WHO), the gap in access to healthcare services between high- and low-income countries contributes to delayed detection, increased incidence of advanced-stage disease, and, consequently, higher mortality rates (up to 50% higher compared to high-income countries) [<span>1, 2</span>]. This translates into inequalities in access to screening and early diagnosis methods, which exacerbate the burden of this disease in low-resource settings where infrastructure, funding, and access to trained professionals are limited [<span>3</span>]. These limitations hinder the implementation of resource-dependent strategies required to achieve evidence-based outcomes, such as clinical breast exams (which necessitate trained personnel) or screening mammography (which requires appropriate infrastructure and trained specialists with adequate operator concordance) [<span>4</span>].</p><p>The use of artificial intelligence (AI) and emerging health technologies, particularly in the field of breast cancer screening, has shown to significantly enhance diagnostic accuracy and reduce operational costs in delivering comprehensive breast health services [<span>5</span>]. For instance, AI enables the development of low-cost imaging analysis systems, such as for mammograms and ultrasounds, that can be implemented in resource-limited settings [<span>5</span>]. Recent evidence suggests that these technologies can match or even exceed the diagnostic accuracy of radiologists in detecting suspicious lesions, a critical advancement in regions facing a shortage of these professionals [<span>6</span>].</p><p>A common limitation in low- and middle-income countries is the presence of cultural and social barriers, often related to the preferences, values, and needs of women [<span>7</span>]. In ancestral, conservative, and vulnerable communities, there is a notable level of mistrust and resistance toward certain interventions, primarily when these do not account for factors that benefit their communities [<span>7</span>]. Integrating women's values and preferences is essential for the success of any public health program. Previous research has indicated that women in these communities prefer noninvasive methods that reduce pain and minimize the risk of unnecessary radiation exposure [<span>7</span>]. AI-based technologies can personalize the screening experience, making it less invasive and more aligned with patient needs, thereby enhancing acceptability and adherence [<span>5</span>]. This approach can help overcome barriers such as language, physical exposure, direct palpation, among others, which strengthens trust and demonstrates
乳腺癌是全球妇女癌症相关死亡的主要原因,其发病率持续上升,特别是在低收入和中等收入国家,对全球公共卫生构成重大挑战。根据卫生计量与评估研究所(IHME)和世界卫生组织(WHO)的数据,高收入国家和低收入国家在获得卫生保健服务方面的差距导致疾病发现延迟、晚期疾病发病率增加,从而导致更高的死亡率(与高收入国家相比高出50%)[1,2]。这就导致在获得筛查和早期诊断方法方面存在不平等现象,在基础设施、资金和获得训练有素的专业人员的机会有限的资源匮乏环境中,这种情况加剧了该病的负担。这些限制阻碍了实现循证结果所需的资源依赖型策略的实施,例如临床乳腺检查(需要训练有素的人员)或乳房x光筛查(需要适当的基础设施和训练有素的专家,并与操作人员有足够的一致性)。人工智能和新兴保健技术的使用,特别是在乳腺癌筛查领域的使用,已显示出在提供全面乳腺保健服务方面可显著提高诊断准确性并降低运营成本。例如,人工智能可以开发低成本的成像分析系统,例如乳房x光检查和超声波检查,这些系统可以在资源有限的环境中实施。最近的证据表明,在检测可疑病变方面,这些技术可以匹配甚至超过放射科医生的诊断准确性,这在面临这些专业人员短缺的地区是一个关键的进步。低收入和中等收入国家的一个共同限制是存在文化和社会障碍,这些障碍通常与妇女的偏好、价值观和需求有关。在祖传的、保守的和脆弱的社区中,对某些干预措施存在着明显的不信任和抵制,特别是当这些干预措施没有考虑到有利于他们社区的因素时。综合妇女的价值观和偏好对任何公共卫生方案的成功都至关重要。先前的研究表明,这些社区的妇女更喜欢非侵入性的方法,以减少疼痛和减少不必要的辐射暴露的风险。基于人工智能的技术可以个性化筛查体验,使其侵入性更小,更符合患者需求,从而提高可接受性和依从性。这种方法可以帮助克服语言、身体接触、直接触诊等障碍,从而加强信任,并显示出保护这些妇女健康的附加价值。为了使基于人工智能的技术在资源匮乏的环境中充分发挥其早期检测潜力,需要进行规划,包括培训医疗保健专业人员、确保项目的经济可持续性以及开发适当的基础设施。卫生系统必须优先考虑这些设备和人工智能算法的可及性,优化其在筛查和早期诊断选择有限的偏远地区的应用。为了说明目前关于女性在乳腺癌筛查中的偏好、价值观和需求的主要证据的可得性方面的知识和人口差距,进行了一项简短的混合方法科学计量学分析。这包括来自开放获取数据库的最新全球卫生指标,特别是来自全球癌症观察站(GLOBOCAN)和世卫组织全球卫生观察站,重点是乳腺癌。PubMed上的半结构化搜索产生了82个结果,经过人工审查,只有15个原始研究在世界范围内被确定。只有11个国家发表了至少一篇关于这一主题的原创文章,其中美国的出版物数量最多,尽管只有四篇文章(图1)。与年龄调整后的发病率和死亡率相比,在具有乳腺癌筛查偏好、价值观和需求证据的国家中,乳腺癌造成的疾病负担与表明缺乏对这一社会心理、文化和医疗保健过程的全面了解的出版物数量之间存在显著差异(图1)。根据全球卫生指标,非洲、亚洲和拉丁美洲的国家,如牙买加(35.21)、尼日利亚(26.8)、伊拉克(23.51)、多米尼加共和国(23.03)、乌拉圭(21.57)和哥伦比亚(13.29),在全世界每10万人中乳腺癌死亡率最高的国家中,甚至没有一份关于这一主题的出版物。 这些结果反映了在探索基于人工智能的乳腺护理健康技术方面存在显著的知识和人口差距,必须考虑文化、社会和医疗保健方面的因素,以确保这些项目的成功。为什么关于这个话题的证据如此有限?一种可能的解释是,全球卫生工作历来优先发展诊断基础设施、劳动力培训和成像可用性。但这些策略并没有充分解决筛查项目的社会心理和文化层面的问题。这一差距导致了服务利用不足、晚期诊断和持续的卫生不公平现象。与传统的放射科医生的解释相比,基于人工智能的乳腺癌筛查的最新进展显示出非劣等性,在某些情况下具有优势。例如,MASAI试验[6]表明,人工智能支持的乳房x光检查是安全且诊断准确的,在放射学工作人员有限的卫生系统中提供了一种可行的替代方案[6]。此外,基于人工智能的成像工具可以使用不同的数据集进行训练,以检测异常,使其适应资源匮乏的环境,无法获得乳房x光检查或专业知识[10]。这些系统能够自动检测并突出显示乳房图像中的可疑区域(例如,微钙化、肿块或结构扭曲),提供风险分层评分,并根据严重程度[8]协助对病例进行优先排序。一些算法生成结构化报告或建议可能的诊断,促进临床决策,特别是在放射科医生稀缺或负担过重的地方。另一些可以与便携式成像设备集成并离线运行,这使得它们在没有强大的互联网或电力基础设施的农村和服务不足地区可行。这些功能减少了诊断周转时间,增强了诊断一致性,提高了早期检测服务的可访问性,同时最大限度地降低了运营成本。然而,尽管有这些技术进步,这种革新的效力在很大程度上取决于它们为目标人口所接受和利用的程度。文化污名化、恐惧、对医疗系统的不信任以及缺乏文化上适当的卫生交流已被认为是脆弱社区早期乳腺癌筛查的主要障碍[b]。在这些情况下,侵入性手术或需要身体接触的手术可能会进一步加剧不信任或恐惧。相比之下,非侵入性的、人工智能支持的模式,如基于图像的分析,与最少的人类互动,可以减轻这些障碍,使妇女更愿意参与常规筛查[10,11]。这篇简短的科学计量学分析揭示了关于女性在乳腺癌筛查中的偏好、价值观和需求的初步研究在数量和地理分布方面存在显著差距。乳腺癌年龄调整死亡率最高的国家往往没有针对这一主题的原始研究。这一发现与先前的文献一致,强调了疾病负担与当地相关研究成果之间的不匹配[3,12]。其影响是令人担忧的:在缺乏情境证据的情况下,筛查项目可能无法达到那些风险最高的人,或者可能因与社区期望和信念不一致而被拒绝。此外,新出现的研究强调了将公共卫生技术与妇女观点结合起来的重要性。Carter等人发现,当以文化敏感的方式告知女性人工智能辅助筛查的益处、风险和影响时,她们更有可能接受人工智能辅助筛查。这加强了将社区参与和卫生扫盲战略与技术实施相结合以优化成果的必要性。从卫生系统的角度来看,采用无创、人工智能支持的战略符合世卫组织全球乳腺癌倡议等全球目标,该倡议倡导根据低收入和中等收入国家的实际情况采取可扩展、具有成本效益的干预措施。这些技术不仅减少了诊断延误和人力资源瓶颈,而且还提供了设计更具包容性、响应性和可持续性的筛查模式的机会。通过将妇女的偏好和信任集中在这些系统中,我们可以提高规划的可接受性和影响,特别是在卫生创新工作中历史上被边缘化的地区[14,15]。全球健康指标预测,如果实施得当,这些技术可以大大缩小在获得乳腺癌早期诊断方面的差距,从而实现更包容和公平的护理。
{"title":"Noninvasive Breast Cancer Screening Strategies Supported by AI-Based Technologies in Resource-Limited Settings: Is It the Best Opportunity to Strengthen Women's Preferences, Values and Acceptability?","authors":"Wolmark Xiques-Molina,&nbsp;Ivan David Lozada-Martinez,&nbsp;Ornella Fiorillo-Moreno,&nbsp;Alexis Narvaez-Rojas","doi":"10.1002/hcs2.70025","DOIUrl":"https://doi.org/10.1002/hcs2.70025","url":null,"abstract":"&lt;p&gt;Breast cancer is the leading cause of cancer-related mortality in women globally, with its incidence continuing to rise, particularly in low- and middle-income countries, presenting a significant public health challenge worldwide [&lt;span&gt;1&lt;/span&gt;]. According to data from the Institute for Health Metrics and Evaluation (IHME) and the World Health Organization (WHO), the gap in access to healthcare services between high- and low-income countries contributes to delayed detection, increased incidence of advanced-stage disease, and, consequently, higher mortality rates (up to 50% higher compared to high-income countries) [&lt;span&gt;1, 2&lt;/span&gt;]. This translates into inequalities in access to screening and early diagnosis methods, which exacerbate the burden of this disease in low-resource settings where infrastructure, funding, and access to trained professionals are limited [&lt;span&gt;3&lt;/span&gt;]. These limitations hinder the implementation of resource-dependent strategies required to achieve evidence-based outcomes, such as clinical breast exams (which necessitate trained personnel) or screening mammography (which requires appropriate infrastructure and trained specialists with adequate operator concordance) [&lt;span&gt;4&lt;/span&gt;].&lt;/p&gt;&lt;p&gt;The use of artificial intelligence (AI) and emerging health technologies, particularly in the field of breast cancer screening, has shown to significantly enhance diagnostic accuracy and reduce operational costs in delivering comprehensive breast health services [&lt;span&gt;5&lt;/span&gt;]. For instance, AI enables the development of low-cost imaging analysis systems, such as for mammograms and ultrasounds, that can be implemented in resource-limited settings [&lt;span&gt;5&lt;/span&gt;]. Recent evidence suggests that these technologies can match or even exceed the diagnostic accuracy of radiologists in detecting suspicious lesions, a critical advancement in regions facing a shortage of these professionals [&lt;span&gt;6&lt;/span&gt;].&lt;/p&gt;&lt;p&gt;A common limitation in low- and middle-income countries is the presence of cultural and social barriers, often related to the preferences, values, and needs of women [&lt;span&gt;7&lt;/span&gt;]. In ancestral, conservative, and vulnerable communities, there is a notable level of mistrust and resistance toward certain interventions, primarily when these do not account for factors that benefit their communities [&lt;span&gt;7&lt;/span&gt;]. Integrating women's values and preferences is essential for the success of any public health program. Previous research has indicated that women in these communities prefer noninvasive methods that reduce pain and minimize the risk of unnecessary radiation exposure [&lt;span&gt;7&lt;/span&gt;]. AI-based technologies can personalize the screening experience, making it less invasive and more aligned with patient needs, thereby enhancing acceptability and adherence [&lt;span&gt;5&lt;/span&gt;]. This approach can help overcome barriers such as language, physical exposure, direct palpation, among others, which strengthens trust and demonstrates","PeriodicalId":100601,"journal":{"name":"Health Care Science","volume":"4 4","pages":"310-313"},"PeriodicalIF":3.3,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/hcs2.70025","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144888494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Failure Rate of Internal Fixation Increases With Sagittal Displacement of the Femoral Head: A Retrospective Study 股骨头矢状位移位增加内固定失败率:一项回顾性研究
IF 3.3 Pub Date : 2025-06-30 DOI: 10.1002/hcs2.70022
Lei Shi, Chen Chen, Junsong Wang, Yuanhao Wu, Jia Li, Houchen Lyu, Quanyi Guo, Peifu Tang

Background

The risk of internal fixation failure remains relatively high in stable femoral neck fracture (FNF) (Garden I or II). Preoperative sagittal displacement of the femoral head has been proposed as a potential influencing factor. This study aimed to evaluate the impact of sagittal displacement on the outcomes of cannulated screw internal fixation (CSIF) in patients with stable FNF (Garden I or II) by reconstructing the axial sagittal oblique plane of the fracture using preoperative computed tomography (CT) imaging.

Methods

This study included 167 patients with FNF who underwent CSIF. The sagittal tilt angle of the femoral head (STAFH) was evaluated using three-dimensional CT (3D-CT). The distribution of preoperative STAFH was analyzed, and its independent association with treatment failure was assessed. Treatment failure was defined as the need for revision surgery within 2 years postoperatively due to avascular necrosis, nonunion, or internal fixation failure.

Results

Among the 167 patients, 9 (5.4%) exhibited anterior tilt (AT) of the femoral head, 158 (94.60%) presented with posterior tilt (PT). A total of 50 patients (29.9%) demonstrated excessive sagittal displacement (AT ≥ 10° or PT ≥ 20°). In the failure group, 80.0% of patients had excessive sagittal displacement compared to 28.1% in the healed group. Excessive sagittal displacement was significantly associated with an increased risk of surgical failure (odds ratio: 11.953, 95% CI: 3.656–39.083, p < 0.05).

Conclusions

In patients with Garden I or II FNF, greater preoperative sagittal displacement of the femoral head was correlated with a higher likelihood of CSIF failure. AT ≥ 10° or PT ≥ 20° were identified as independent predictors of CSIF failure in FNF patients. Nevertheless, these findings still require confirmation through prospective, multi-center clinical trials with large sample sizes.

背景稳定性股骨颈骨折(FNF) (Garden I或II)内固定失败的风险仍然相对较高。术前股骨头矢状移位被认为是一个潜在的影响因素。本研究旨在评估矢状位移位对稳定型FNF (Garden I或II)患者空心螺钉内固定(CSIF)效果的影响,通过术前计算机断层扫描(CT)成像重建骨折的轴向矢状位斜平面。方法167例FNF患者行CSIF。利用三维CT (3D-CT)评估股骨头矢状倾斜角度(STAFH)。分析术前STAFH的分布,并评估其与治疗失败的独立相关性。治疗失败定义为术后2年内因无血管坏死、骨不连或内固定失败需要翻修手术。结果167例患者中,股骨头前倾9例(5.4%),后倾158例(94.60%)。共有50例(29.9%)患者表现为矢状位过度移位(AT≥10°或PT≥20°)。在失败组中,80.0%的患者矢状位过度移位,而愈合组为28.1%。矢状位过度移位与手术失败风险增加显著相关(优势比:11.953,95% CI: 3.656-39.083, p < 0.05)。结论在Garden I或II型FNF患者中,术前股骨头矢状位移位较大与CSIF衰竭的可能性较高相关。AT≥10°或PT≥20°被确定为FNF患者CSIF失败的独立预测因子。然而,这些发现仍然需要通过前瞻性、多中心、大样本量的临床试验来证实。
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引用次数: 0
Sex-Related Differences in Risk Factors Associated With Nonhealing or Recurrence of Hyperthyroidism in Patients With Graves' Disease Treated With Radioactive Iodine 放射性碘治疗Graves病患者甲状腺功能亢进不愈合或复发相关危险因素的性别差异
Pub Date : 2025-06-13 DOI: 10.1002/hcs2.70021
Haolin Shen, Yuegui Wang, Jianmei Liao, Xianbo Zuo, Bo Zhang, Xiao Yang

Background

To evaluate sex-related differences in the risk factors associated with nonhealing or recurrence of hyperthyroidism (NHRH) in patients with Graves' disease (GD) treated with radioactive iodine.

Methods

In total, 285 patients were enrolled. Data on radioactive iodine (RAI) dosage, ultrasound indexes of the thyroid, and other clinical factors were collected. Patients were divided into NHRH and non-NHRH (hypothyroidism or euthyroidism) groups based on treatment outcomes. Univariate and multivariate weighted logistic regression analyses were used to identify factors associated with NHRH. Sex-specific analyses of these risk factors were also conducted.

Results

There were no significant differences between the two groups in terms of sex, thyroid shear wave elastography velocity values, or pretreatment serum free thyroxine (FT4) levels. Thyroid volume and age were independently associated with NHRH, with the odds of NHRH gradually decreasing as age increased. In subgroup analyses, both age and thyroid volume were independent risk factors for NHRH in female patients (p < 0.05), while in male patients, only FT4 was independently associated with NHRH (p < 0.05).

Conclusions

In patients of different sexes, the influence of thyroid volume, age, and FT4 on treatment outcomes exhibits distinct patterns.

背景:评价放射性碘治疗Graves病(GD)患者甲状腺功能亢进(NHRH)不愈合或复发相关危险因素的性别差异。方法共纳入285例患者。收集放射性碘(RAI)剂量、甲状腺超声指标及其他临床因素。根据治疗结果将患者分为NHRH组和非NHRH组(甲状腺功能减退或甲状腺功能亢进)。采用单因素和多因素加权logistic回归分析确定与NHRH相关的因素。还对这些危险因素进行了性别分析。结果两组患者在性别、甲状腺剪切波弹性成像速度值、预处理血清游离甲状腺素(FT4)水平等方面均无显著差异。甲状腺体积和年龄与NHRH独立相关,随着年龄的增加,NHRH的发生率逐渐降低。在亚组分析中,年龄和甲状腺体积都是女性患者NHRH的独立危险因素(p < 0.05),而在男性患者中,只有FT4与NHRH独立相关(p < 0.05)。结论在不同性别的患者中,甲状腺体积、年龄和FT4对治疗结果的影响具有不同的模式。
{"title":"Sex-Related Differences in Risk Factors Associated With Nonhealing or Recurrence of Hyperthyroidism in Patients With Graves' Disease Treated With Radioactive Iodine","authors":"Haolin Shen,&nbsp;Yuegui Wang,&nbsp;Jianmei Liao,&nbsp;Xianbo Zuo,&nbsp;Bo Zhang,&nbsp;Xiao Yang","doi":"10.1002/hcs2.70021","DOIUrl":"https://doi.org/10.1002/hcs2.70021","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>To evaluate sex-related differences in the risk factors associated with nonhealing or recurrence of hyperthyroidism (NHRH) in patients with Graves' disease (GD) treated with radioactive iodine.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>In total, 285 patients were enrolled. Data on radioactive iodine (RAI) dosage, ultrasound indexes of the thyroid, and other clinical factors were collected. Patients were divided into NHRH and non-NHRH (hypothyroidism or euthyroidism) groups based on treatment outcomes. Univariate and multivariate weighted logistic regression analyses were used to identify factors associated with NHRH. Sex-specific analyses of these risk factors were also conducted.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>There were no significant differences between the two groups in terms of sex, thyroid shear wave elastography velocity values, or pretreatment serum free thyroxine (FT4) levels. Thyroid volume and age were independently associated with NHRH, with the odds of NHRH gradually decreasing as age increased. In subgroup analyses, both age and thyroid volume were independent risk factors for NHRH in female patients (<i>p</i> &lt; 0.05), while in male patients, only FT4 was independently associated with NHRH (<i>p</i> &lt; 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>In patients of different sexes, the influence of thyroid volume, age, and FT4 on treatment outcomes exhibits distinct patterns.</p>\u0000 </section>\u0000 </div>","PeriodicalId":100601,"journal":{"name":"Health Care Science","volume":"4 3","pages":"188-194"},"PeriodicalIF":0.0,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/hcs2.70021","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144367498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Examining Reasons for Using Non-Primary Care Providers as Usual Source of Health Care: Insights From the All of Us Study 检查使用非初级保健提供者作为通常卫生保健来源的原因:来自我们所有人研究的见解
Pub Date : 2025-06-08 DOI: 10.1002/hcs2.70020
Abbey Gregg, Hui Wang, Brankeciara Ard, Marcelo Takejame Galafassi, Maryam Bidgoli

Introduction

Having a primary care usual source of care (USC) is associated with better population health outcomes. However, the percent of adults in the United States (US) with a usual primary care provider is declining. We sought to identify factors associated with establishing a USC at an urgent care clinic or emergency department as opposed to primary care.

Methods

We analyzed data from 57,152 participants in the All of Us study who reported having a USC. We used the Andersen Behavioral Model of Health Services Use framework and multivariable logistic regression to examine associations among predisposing, enabling, and need factors, according to the source of usual care.

Results

An urgent care clinic, minute clinic, or emergency department was the source of usual care for 6.3% of our sample. The odds of seeking care at this type of facility increased with younger age, lower educational attainment, and better health status. Black and Hispanic individuals, as well as those who reported experiencing discrimination in medical settings or that their provider was of a different race and ethnicity, were also less likely to have a primary care USC. Financial concerns, being anxious about seeing a provider, and the inability to take time off from work also increased the likelihood of having a non-primary care USC.

Conclusions

Improving the rates of having a primary care USC among younger and healthy adults may be achievable through policies that can improve access to convenient, affordable primary care. Efforts to improve diversity among primary care providers and reduce discrimination experienced by patients may also improve the USC rates for racial and ethnic minority groups.

拥有初级保健通常护理来源(USC)与更好的人口健康结果相关。然而,在美国,接受常规初级保健服务的成年人比例正在下降。我们试图确定在紧急护理诊所或急诊科建立USC而不是在初级保健的相关因素。方法:我们分析了57,152名“我们所有人”研究中报告患有南加州大学的参与者的数据。我们使用Andersen卫生服务使用行为模型框架和多变量逻辑回归来检查根据常规护理来源的易感因素、使能因素和需求因素之间的关联。结果急诊诊所、分诊诊所或急诊科是我们样本中6.3%的常规护理来源。年龄越小,受教育程度越低,健康状况越好,在这类机构寻求治疗的几率越高。黑人和西班牙裔个人,以及那些报告在医疗环境中遭受歧视或他们的提供者是不同种族和民族的人,也不太可能有初级保健南加州大学。经济问题、对看医生感到焦虑以及无法从工作中抽出时间也增加了非初级保健南加州大学的可能性。结论:提高年轻健康成人的初级保健USC率可以通过政策来实现,这些政策可以改善获得方便、负担得起的初级保健的机会。努力提高初级保健提供者的多样性,减少患者遭受的歧视,也可能提高种族和少数民族群体的USC率。
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引用次数: 0
Smart Healthcare: The Role of Digital Health in Modern Medicine 智能医疗:数字健康在现代医学中的作用
Pub Date : 2025-06-01 DOI: 10.1002/hcs2.70019
Nidha Shapoo, Naveed Shapoo, Abdul Rehman, Noella Boma

Digital health is transforming healthcare by integrating advanced technologies to make healthcare more accessible, efficient, and personalized. From electronic health records, telemedicine, wearable devices, and artificial intelligence to the recent smart hospitals, digital health is improving patient care and outcomes while reducing healthcare costs. However, the integration of digital health faces several challenges, including data privacy, cybersecurity risks, and inequitable access to technology. This article provides an overview of the current state of digital health, key challenges in implementation, and potential solutions to maximize the benefits of digital health and ensure efficient, equitable, and patient-centered healthcare in the future.

数字医疗正在通过集成先进技术,使医疗保健更容易获得、更高效、更个性化,从而改变医疗保健行业。从电子健康记录、远程医疗、可穿戴设备和人工智能到最近的智能医院,数字健康正在改善患者护理和结果,同时降低医疗成本。然而,数字健康的整合面临着一些挑战,包括数据隐私、网络安全风险和获取技术的不公平。本文概述了数字健康的当前状态、实现中的主要挑战,以及最大限度地发挥数字健康效益并确保未来高效、公平和以患者为中心的医疗保健的潜在解决方案。
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引用次数: 0
Advancing Mental Health Care: A Comprehensive Review of Digital Tools and Technologies for Enhancing Diagnosis, Treatment, and Wellness 推进精神卫生保健:加强诊断、治疗和健康的数字工具和技术的全面回顾
Pub Date : 2025-05-31 DOI: 10.1002/hcs2.70018
Muhammad Khalid Anser, Agha Amad Nabi, Ishfaq Ahmad, Muhammad Moinuddin Qazi Abro, Khalid Zaman

An individual's mental health influences their capacity to think effectively, feel emotionally stable, and perform daily activities. As mental health concerns become more prevalent worldwide, new awareness and diagnostic and treatment tactics are needed. Digital tools and technology are helping solve these problems by providing scalable, tailored solutions for large populations. This detailed review examines mental health-promoting internet tools. Smartphone applications, web-based therapy systems, wearable tech, artificial intelligence-powered resources, and virtual reality (VR) technologies were evaluated for efficacy and side effects. PubMed, PsycINFO, Scopus, IEEE Xplore, and Google Scholar were carefully searched. Search terms included “digital mental health tools,” “online therapy,” and “AI in mental health.” Randomized controlled trials, cohort studies, cross-sectional studies, systematic reviews, and meta-analyses of digital technology and mental health were included from among the literature published after 2010. Cognitive behavioral therapy methods, mood monitoring, and mindfulness exercises are among the numerous features of smartphone applications that have been demonstrated to mitigate symptoms of anxiety, depression, and tension. Online therapy platforms let marginalized individuals obtain therapy remotely. Wearable technology may detect heart rate, blood pressure, and sleep length, which may reveal mental health difficulties. Chatbots employ machine learning algorithms and natural language processing to deliver customized support and show promise for quick intervention. Exposure therapy for anxiety and trauma is increasingly using virtual reality environments. Although digital mental health therapies face challenges in relation to data privacy, limited long-term efficacy, and technological inequality, digital technologies are modernizing mental healthcare. By offering inexpensive and effective alternatives to traditional therapies, digital technologies may help healthcare systems meet the growing demand for mental health services and overall well-being.

一个人的心理健康会影响他们有效思考、情绪稳定和日常活动的能力。随着心理健康问题在世界范围内变得越来越普遍,需要新的认识和诊断和治疗策略。数字工具和技术正在帮助解决这些问题,为大量人口提供可扩展的、量身定制的解决方案。这篇详细的综述检查了促进心理健康的互联网工具。对智能手机应用、基于网络的治疗系统、可穿戴技术、人工智能驱动的资源和虚拟现实(VR)技术的疗效和副作用进行了评估。PubMed、PsycINFO、Scopus、IEEE explore和b谷歌Scholar都进行了仔细的检索。搜索词包括“数字心理健康工具”、“在线治疗”和“心理健康中的人工智能”。2010年以后发表的文献中包括了数字技术与心理健康的随机对照试验、队列研究、横断面研究、系统评价和荟萃分析。认知行为疗法、情绪监测和正念练习是智能手机应用程序的众多功能之一,这些功能已被证明可以减轻焦虑、抑郁和紧张的症状。在线治疗平台让边缘人群获得远程治疗。可穿戴技术可以检测心率、血压和睡眠时长,这可能会揭示心理健康问题。聊天机器人采用机器学习算法和自然语言处理来提供定制支持,并显示出快速干预的前景。焦虑和创伤的暴露疗法越来越多地使用虚拟现实环境。尽管数字心理健康疗法在数据隐私、有限的长期疗效和技术不平等方面面临挑战,但数字技术正在使心理保健现代化。通过提供传统疗法的廉价而有效的替代方案,数字技术可以帮助医疗保健系统满足对精神卫生服务和整体福祉日益增长的需求。
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引用次数: 0
Telemedicine in Action: Improving Perceived Healthcare Accessibility in Rural China 远程医疗在行动:改善中国农村医疗可及性
Pub Date : 2025-05-29 DOI: 10.1002/hcs2.70017
Zhongmou Huang, Xizi Wan, Shaojie Zhou, Miao Yu

Objective

The scarcity of healthcare resources and inadequate access to medical services in rural and remote areas are pervasive challenges many countries face, particularly in the developing world. Telemedicine, with its capacity to overcome geographical barriers and provide patients with real-time medical services, has shown considerable potential in addressing these issues, attracting widespread attention. Compact medical communities and family doctor systems play important roles in improving healthcare accessibility. However, despite the critical nature of patients' perceptions of healthcare accessibility, research in this domain is sparse. This study aimed to explore the impact of telemedicine on rural residents' perceived healthcare accessibility in China, analyze the mechanisms underpinning this relationship, and elucidate the roles of compact medical communities and the family doctor system.

Methods

Survey data from 3311 rural residents were analyzed using a probit model, instrumental variables, and subgroup regression analyses to ascertain causal effects, perform heterogeneity analysis, examine mechanisms, and ascertain the robustness of the findings.

Results

Telemedicine significantly enhanced rural residents' perceived healthcare accessibility, with particularly notable benefits for those in sparsely populated areas, regions with high-speed internet access, within the purview of compact healthcare consortiums, and those with access to family doctor services. Furthermore, telemedicine improved rural residents' perceived healthcare accessibility by encouraging the use of primary care services.

Conclusion

Telemedicine in China has played a significant role in improving the perceived healthcare accessibility among rural residents and aiding in the reduction of disparities in accessibility across different demographic groups. This is consistent with the broader objective of achieving universal health coverage. However, the efficacy of telemedicine in enhancing healthcare accessibility is contingent upon certain preconditions. Policymakers must confront local infrastructure challenges, particularly regarding internet connectivity, when expanding telemedicine services to ensure their effective operation. The synergistic interaction observed between telemedicine, the family doctor system, and compact medical communities highlights the importance of integrating telemedicine into existing healthcare systems

在农村和偏远地区,保健资源短缺和获得医疗服务的机会不足是许多国家,特别是发展中国家普遍面临的挑战。远程医疗有能力克服地理障碍并向患者提供实时医疗服务,在解决这些问题方面显示出相当大的潜力,引起了广泛关注。紧凑的医疗社区和家庭医生系统在改善卫生保健可及性方面发挥着重要作用。然而,尽管患者对医疗保健可及性的看法至关重要,但这一领域的研究却很少。本研究旨在探讨远程医疗对中国农村居民感知医疗可及性的影响,分析这种关系的机制,并阐明紧凑型医疗社区和家庭医生制度的作用。方法采用probit模型、工具变量和亚组回归分析等方法对3311名农村居民的调查数据进行分析,确定因果关系,进行异质性分析,检验机制,并确定研究结果的稳健性。结果远程医疗显著提高了农村居民对医疗可及性的感知,对人口稀少地区、高速互联网接入地区、紧凑型医疗联盟范围内的地区和可获得家庭医生服务的地区尤其显著。此外,远程医疗通过鼓励使用初级保健服务,改善了农村居民对保健可及性的感知。结论远程医疗在提高农村居民医疗可及性方面发挥了重要作用,有助于缩小不同人口群体之间的可及性差异。这与实现全民健康覆盖的更广泛目标是一致的。然而,远程医疗在提高医疗可及性方面的效力取决于某些先决条件。决策者在扩大远程医疗服务以确保其有效运作时,必须面对当地基础设施的挑战,特别是在互联网连接方面。远程医疗、家庭医生系统和紧凑的医疗社区之间观察到的协同作用突出了将远程医疗整合到现有医疗保健系统中的重要性。这种整合可以加强与现有卫生保健框架的协作,确保提供安全、可获得和负担得起的卫生保健服务,并促进当地人口的健康和福祉。
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引用次数: 0
Surgical and Medical Co-Management in an 82-Year-Old Patient With Hemophilia a Undergoing Pancreaticoduodenectomy 82岁血友病a行胰十二指肠切除术的外科与内科联合治疗1例
Pub Date : 2025-05-25 DOI: 10.1002/hcs2.70016
Wenning Lu, Chaoyang Liu, Jing He, Rui Cheng

We report the successful application of a surgical and medical co-management (SMC) strategy in an 82-year-old man with hemophilia A (HA) undergoing pancreaticoduodenectomy for pancreatic head carcinoma. No major complications or perioperative bleeding occurred. Optimal management of HA patients undergoing major surgery requires multidisciplinary coordination to avoid postoperative complications. The SMC team integrates internists (who assess chronic disease status, adjust medications, and determine best hemostatic therapies) and surgeons (who evaluate the surgical feasibility of procedures and rely on advanced surgical skills) to improve perioperative planning to minimize complications and promote recovery. This case illustrates the utility of a shift from passive and conservative treatment to active and preventive treatment and highlights the value of SMC in many complex clinical situations.

我们报道一例82岁男性血友病a (HA)因胰头癌行胰十二指肠切除术成功应用外科和医疗共同管理(SMC)策略。无重大并发症及围手术期出血。对接受大手术的HA患者进行优化管理需要多学科协调,以避免术后并发症。SMC团队整合了内科医生(评估慢性疾病状态、调整药物和确定最佳止血疗法)和外科医生(评估手术的可行性并依靠先进的外科技术)来改进围手术期计划,以减少并发症并促进康复。这个病例说明了从被动和保守治疗到主动和预防性治疗的转变,并强调了SMC在许多复杂的临床情况中的价值。
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引用次数: 0
期刊
Health Care Science
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