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Building sustainable capacity for better access to diabetes care in low-resource settings: A critical review of global efforts and integrated strategies 建设可持续能力,改善低资源环境下的糖尿病护理服务:全球努力和综合战略的重要回顾
Pub Date : 2024-03-25 DOI: 10.1002/hcs2.89
Emmanuel Lamptey

The alarming state of global insulin access in low-resource settings presents a major barrier to diabetes care. A comprehensive review of these challenges is lacking at the global level. To address this weakness, enhance affordability and build capacity for a more sustainable approach to scaling up access. This review analyzes the specific issue of inconsistent access to insulin in low- and middle-income countries. Using this analysis, we mapped the scope and intensity of issues such as the unaffordability and unavailability of insulin. We also identified six innovative and integrative strategies for increasing and securing accessibility in the areas of policy making, marketing, clinical practice, health education, domestication, and multisectoral approaches.

全球资源匮乏地区的胰岛素使用情况令人担忧,这是糖尿病护理的一大障碍。全球范围内缺乏对这些挑战的全面审查。为了解决这一薄弱环节,提高可负担性和能力建设,以更可持续的方式扩大获取范围。本综述分析了中低收入国家胰岛素供应不稳定这一具体问题。通过这一分析,我们确定了胰岛素负担不起和无法获得等问题的范围和严重程度。我们还在政策制定、市场营销、临床实践、健康教育、本土化和多部门方法等领域确定了六项创新性综合战略,以提高和确保可及性。
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引用次数: 0
Socioeconomic support, quality of life, and prognosis of frailty among the older adults 老年人的社会经济支持、生活质量和虚弱预后
Pub Date : 2024-03-25 DOI: 10.1002/hcs2.88
Huai-Yu Wang, Yuming Huang, Meng-Ru Zhou, Hao-Yue Jiang, Yu-Han Zong, Xi-Huan Zhu, Xiaojing Sun

Background

Although socioeconomic support is recommended for frailty management, its association with the prognosis of frailty is unclear.

Methods

Using data from participants aged ≥65 years in the Chinese Longitudinal Healthy Longevity Survey (2008–2018), the associations between socioeconomic support (source of income, medical insurance, community support, living status), onset of prefrailty/frailty, and worsening of prefrailty, were analyzed using multinominal logistic regression models. The associations between self-reported low quality of life (QoL) and reversion of prefrailty/frailty were analyzed using multivariate logistic regression models. Associations with mortality risk were analyzed using Cox proportional hazard regression models.

Results

A total of 13,859 participants (mean age: 85.8 ± 11.1 years) containing 2056 centenarians were included. Financial dependence was a risk factor for low QoL among prefrail/frail individuals, but not among robust individuals. Having commercial or other insurance, and receiving social support from the community were protective factors for low QoL among prefrail/frail individuals and for the worsening of prefrailty. Continuing to work was a risk factor for low QoL, but a protective factor for worsening of prefrailty. A negative association between continuing to work and mortality existed in prefrail individuals aged <85 years and ≥85 years. Living alone was a risk factor for low QoL, but was not significantly associated with frailty prognosis.

Conclusions

Prefrail and frail individuals were vulnerable to changes in socioeconomic support and more sensitive to it compared with robust individuals. Preferential policies regarding financial support, social support, and medical insurance should be developed for individuals with frailty.

利用中国健康长寿纵向调查(2008-2018年)中年龄≥65岁的参与者的数据,采用多项式逻辑回归模型分析了社会经济支持(收入来源、医疗保险、社区支持、生活状况)、虚弱前期/虚弱的发生以及虚弱前期恶化之间的关系。使用多变量逻辑回归模型分析了自我报告的低生活质量(QoL)与虚弱前期/虚弱期恢复之间的关系。共纳入 13859 名参与者(平均年龄:85.8 ± 11.1 岁),其中包括 2056 名百岁老人。经济依赖是导致预衰老/衰老者生活质量低的一个风险因素,但在健壮者中并非如此。拥有商业保险或其他保险以及从社区获得社会支持是导致早老/衰老者低生活质量和早老恶化的保护因素。继续工作是导致低 QoL 的风险因素,但却是导致体弱前期恶化的保护因素。在年龄小于 85 岁和大于 85 岁的体弱多病者中,继续工作与死亡率之间存在负相关。独居是导致低生活质量的一个风险因素,但与虚弱预后并无显著关联。与体格健壮的人相比,虚弱前期和虚弱的人容易受到社会经济支持变化的影响,而且对这种变化更加敏感。应为体弱者制定经济支持、社会支持和医疗保险方面的优惠政策。
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引用次数: 0
The importance of public engagement in clinical xenotransplantation 公众参与临床异种移植的重要性
Pub Date : 2024-03-25 DOI: 10.1002/hcs2.91
Daniel J. Hurst, David K. C. Cooper

Over the past several decades, significant scientific progress in xenotransplantation has brought the field to the threshold of clinical trials. In the past 3 years in the United States, experimental pig kidney and heart xenotransplantation have been performed on human subjects recently declared dead by neurological criteria (decedents). In addition, two pig heart transplants have been carried out in living patients under the United States Food and Drug Administration's expanded access guidelines. However, though there has been a flurry of activity there remain unanswered questions regarding how the public views xenotransplantation, what concerns may exist, and how to address these concerns in a meaningful way. This paper aims to underscore the importance of public engagement in xenotransplantation, emphasizing the ongoing need for studies to assess public opinions. The current evidence on public engagement studies is reviewed and gaps in our understanding are identified. We propose practical steps to advance this field. Additional studies to determine the extent of racial/ethnic differences in attitudes to xenotransplantation should be conducted. Empirical and descriptive analysis of certain religious viewpoints—especially minority faiths—would be valuable. As public engagement is an important aspect of public acceptance of novel research that is accompanied by risk, we suggest that xenotransplantation biotechnology companies might consider leading the way in funding this research.

在过去的几十年里,异种移植在科学上取得了重大进展,使这一领域迈入了临床试验的门槛。在过去 3 年中,美国对最近根据神经学标准宣布死亡的人类受试者(死者)进行了实验性猪肾和猪心异种移植。此外,根据美国食品和药物管理局的 "扩大准入准则",已在活着的病人身上进行了两例猪心脏移植手术。然而,尽管出现了一系列活动,但关于公众如何看待异种器官移植、可能存在哪些担忧以及如何有意义地解决这些担忧等问题仍未得到解答。本文旨在强调公众参与异种器官移植的重要性,并强调目前需要对公众意见进行评估研究。本文回顾了目前有关公众参与研究的证据,并指出了我们认识上的差距。我们提出了推动这一领域发展的实际步骤。应开展更多研究,以确定种族/民族对异种器官移植态度的差异程度。对某些宗教观点--尤其是少数民族信仰--进行经验性和描述性分析也很有价值。由于公众参与是公众接受伴随风险的新型研究的一个重要方面,我们建议异种移植生物技术公司可以考虑带头资助这项研究。
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引用次数: 0
Transformations in medical education: A prudential perspective 医学教育的变革:审慎的视角
Pub Date : 2024-03-18 DOI: 10.1002/hcs2.86
Donald Boudreau, Abraham Fuks

A decade ago we asked the question, “Is there something in medicine that is eternal or enduring?” Our aim was to write a manuscript entitled, “That which does not change in medicine.” The publication begins as follows: “The practice of medicine involves continual change, driven by a constant stream of developments in the understanding of biological structure and function relevant to human diseases, and the parallel improvements in pharmacologic and other technological interventions. This change is also driven by evolving social philosophies, ethical trends, and lifestyles.” [1] That preamble reverberates as strongly now as then, perhaps even more so, given the velocity of technological change. When we deliberated on which aspects of medical practice should remain stable, we had few premonitions that implantable chips, robotic surgery, virtual reality, and artificial intelligence (AI) would soon become ubiquitous. The needle has clearly moved, propelled by extraordinary advances in bioengineering, computer and data sciences; major shifts in the governance and organization of clinical practice; and powerful sociocultural trends.

As we explore current transformative developments we are reminded of our earlier conclusions: that certain dimensions of medical practice are, indeed, immutable. Most importantly, the relationship between physician and patient depends on moral obligations, characterized by a compassionate response best described as clinical engagement [2]. The requisite virtues are affective as much as cognitive. The challenge for educators, physicians, and policymakers is to accommodate the benefits of transformational change, both technological and conceptual, whilst remaining true to the fundamental, dyadic clinical relationship. Thus, pedagogic change should welcome innovations but do so with restraint that is, with an attitudinal disposition that is neither cynical nor inhibitory but rather alert and mindful, especially when faced with announcements that a given innovation will solve the problems of an overburdened hospital system. By insisting on a cautious approach we may avoid the pendulum that swings too far, resulting in unintended consequences and costly backtracking to undo the damage of untrammeled enthusiasms.

We consider two illustrative innovations germane to healthcare delivery: one in medical education and one in technology. We try to anticipate and understand impacts and conclude by posing a set of questions that may be useful to those who manage systemic changes.

An innovation, unfolding in medical schools world-wide and often regarded as “transformative,” is competency-based medical education (CBME). We analyze this trend, relying on a hierarchy of knowledge as a frame of reference.

The historian Jill Lepore, using the metaphor of a filing cabinet with four drawers, proposed a categorization of knowledge [3]. Each drawer contains knowledge of a different

第一层主要在医学本科教育(UGME)中形成,被称为 "典型能力",是基础性陈述知识与基本技能的混合体。更高阶的能力,如创造力、好奇心、适应性、谦逊和领导力等,则被推迟到培训的后期阶段,用 "医学的艺术 "这个老生常谈的短语来概括。据称,"艺术 "主要是在实习和独立实践中获得的。这种课程体系强化了 CBME 的还原论,并暗示 CBME 首先需要关注死记硬背的知识和技能,从而削弱了其在 UGME 中的适用性。CBME 的全盘采用与缺乏有力证据证明其优越性之间也存在着明显的脱节。加拿大长期以来一直在推广 CBME,但皇家内科与外科学院的一份报告证实,只有少数住院医师表示支持[7]。可以理解的是,许多地区已经决定放缓向 CBME 的过渡,或者考虑采用能力兼容的方法来取代基于能力的模式。在面对假定是有益的变革时,我们建议进行以下反思:这种变革所代表的知识是否有可能压倒对专业或机构价值不可或缺的其他理解方式?这种变革会不会既是变形也是变革?采用新概念或创新工具会在多大程度上为采用者(在本例中为教育管理者)带来好处,并最终为客户(在本例中为临床教师和学习者)带来更好的结果?也许是时候慢慢来了!人工智能的引入说明了医学界是如何从战略和实用角度接受、采纳和转化新理念的。它既令人兴奋,又具有颠覆性。这项技术在教育和临床领域并行发展。前者的前景和隐患已得到总结[8],而在临床相关任务(如诊断、文档编制、日程安排、工作流程和简单手术)和不同医学专业中引入各种类型人工智能的范围、风险和益处方面的研究、评论和评论文章也层出不穷[9]。为了便于分析,我们将抛开具体的应用模式和领域,从总体上考虑技术的本质。技术一词的词源是希腊语 technē(或拉丁语 ars)--通常译为工艺。古希腊人将technē视为tuchē(运气)的对立面。Tuchē指的是偶然性,即偶然发生的、不受人类控制的事件。技术旨在引入秩序和可预测性。哲学家玛莎-努斯鲍姆(Martha Nussbaum)指出:"Technē .... 是将人类智慧有意识地应用于世界的某个部分,从而对世界进行控制;它涉及对需求的管理以及对未来突发事件的预测和控制"[10]。对突发事件的控制是其主要特征。临床医学被定义为:"一种使用科学的实践活动,必须对未来的突发事件进行预测和控制"[10]:临床医学被定义为:"必须逐一诊断和治疗疾病的科学实践"[11]。这一定义有助于将人工智能置于医疗实践的背景中。人工智能强化了临床医学是 "使用科学 "的概念。它可以通过减少这些临床职责中固有的偶然性来支持医生的诊断、治疗和预后能力。虽然人工智能建立在以千兆字节为单位的 "N "数据库之上,但其在临床实践中的应用必须坚决保持 "一个接一个 "的模式。"亚里士多德区分了与人类在实践领域的活动相关的两个思维分支:制造某物(如锻造瓷盘)和执行某物(如驾船航行)。每种活动都需要不同的认知倾向。前者需要 "技术"(technē)--一种具有以下特征的生产模式:它能识别一组案例的共同特征(即可推广的特征);它能最终产生可定义的结果,而这些结果是外在于参与制作的人的;它能通过因果关系解释现象;它是可直接传授的;它能通过应用经典方法成功地创造出人工制品。技术的这些特点,尤其是规范性方面的特点,与我们前面提到的将能力改造为 CBME 时提出的典型能力层如出一辙。 Phronēsis被译为谨慎或实践智慧。儒家思想中类似的美德是 "仁",由 "义 "调节,引导人们 "考虑突发事件和局部因素"[12]。实践智慧使人能够理解单个事物及其背景因素(即个案的特殊性)。它没有技术那么公式化;需要考虑是否值得,因此与道德判断有关;取决于卓越的品格;结果与行为者密不可分;通过经验学习培养和传播。有观点认为,医疗和教学等实践活动都以 "1 "的 "N "为重点,因此最好从 "phronēsis "的角度来理解这些活动[13, 14]。对哲学争议的讨论超出了本文的范围。我们想说的是,医学和教学推理涉及概括化和特殊化之间的编排。这些活动必须同时整合名学和特学方法,这些概念由哲学家威廉-温德尔班德(Wilhelm Windelband)[15]描述。毫无疑问,人工智能将有助于制定和支持医学中常用的概括和概念。人工智能的产出将改善临床决策,使诊断评估(尤其是依赖视觉解读的诊断评估(如皮肤病学和放射学))和预后越来越准确。人工智能将对世代相传、行之有效的启发式方法进行微调或使其过时。如果临床试验证实,人工智能能改善患者的整体治疗效果,那将是一件好事。然而,重要的不仅仅是无名的 "普通 "病人。单个的个体也非常重要....。人工智能机器人能否像睿智的临床医生那样与饱受痛苦的病人进行交流?社交机器人能否像人类同伴一样,看到病人,理解他们的人格,并在可比的三维空间中陪伴他们踏上治疗之旅?随机对照研究已经证明,基于大型语言模型的系统可以生成与临床相关的问题,并做出与临床医生一样具有同理心的回答[16]。有些人将这些研究结果解释为聊天机器人的 "床边礼仪 "等同于或优于临床医生的证明[17]。这种结论是没有根据的。人际关系和同理心是复杂的、多层面的概念,不能简化为一问一答的二重唱。关于临床用语的两项实证研究揭示了临床用语的一些特征,其中包括有能力维持希望、富有同情心地打破常规、创造一个全神贯注的气泡、以揭示患者护理中心地位的方式接触患者,以及受直觉和直觉等具身感知的影响做出决定[2, 18]。这些,以及道德代理的发展,都不太可能由机器人来实现。人工智能因其辅助功能,特别是在概括、计算和模式识别方面的功能,注定会变得非常受欢迎。然而,就临床和教育领域的特殊化和特异性方法而言,以及就道德决策和临床参与而言,我们认为人工智能永远不会通过审查。第二个理由是要抓紧时间......慢慢来!"数据、信息、知识、智慧 "金字塔被用来代表从拥有未经处理的数据和事实到理解和洞察的智力发展过程。这个金字塔的起源并不确定[19]。我们认为它很有用,尤其是因为它将 "智慧 "置于顶峰。这或许比列波尔(Lepore)将 "奥秘 "置于其知识层次结构的顶层更容易理解[3]。我们建议将实用智慧作为一个理想目标。然而,我们并没有获得这种智慧的神奇秘方。以下本杰明-钱-易(Benjamin Chin-Yee)关于技术的评论可以帮助我们进行必要的思考。他认为,"......技术不仅仅是指物质人工制品,而是描述了一种特定的思维方式和与世界互动的方式;......(技术)不是价值中立的,而是反映了一系列社会选择和人类价值观;......(技术)不是作为固定手段的纯粹目的,而是作为不断发展的手段和目的的连续体"[20]。
{"title":"Transformations in medical education: A prudential perspective","authors":"Donald Boudreau,&nbsp;Abraham Fuks","doi":"10.1002/hcs2.86","DOIUrl":"10.1002/hcs2.86","url":null,"abstract":"<p>A decade ago we asked the question, “Is there something in medicine that is eternal or enduring?” Our aim was to write a manuscript entitled, “That which does not change in medicine.” The publication begins as follows: “The practice of medicine involves continual change, driven by a constant stream of developments in the understanding of biological structure and function relevant to human diseases, and the parallel improvements in pharmacologic and other technological interventions. This change is also driven by evolving social philosophies, ethical trends, and lifestyles.” [<span>1</span>] That preamble reverberates as strongly now as then, perhaps even more so, given the velocity of technological change. When we deliberated on which aspects of medical practice should remain stable, we had few premonitions that implantable chips, robotic surgery, virtual reality, and artificial intelligence (AI) would soon become ubiquitous. The needle has clearly moved, propelled by extraordinary advances in bioengineering, computer and data sciences; major shifts in the governance and organization of clinical practice; and powerful sociocultural trends.</p><p>As we explore current transformative developments we are reminded of our earlier conclusions: that certain dimensions of medical practice are, indeed, immutable. Most importantly, the relationship between physician and patient depends on moral obligations, characterized by a compassionate response best described as clinical engagement [<span>2</span>]. The requisite virtues are affective as much as cognitive. The challenge for educators, physicians, and policymakers is to accommodate the benefits of transformational change, both technological and conceptual, whilst remaining true to the fundamental, dyadic clinical relationship. Thus, pedagogic change should welcome innovations but do so with restraint that is, with an attitudinal disposition that is neither cynical nor inhibitory but rather alert and mindful, especially when faced with announcements that a given innovation will solve the problems of an overburdened hospital system. By insisting on a cautious approach we may avoid the pendulum that swings too far, resulting in unintended consequences and costly backtracking to undo the damage of untrammeled enthusiasms.</p><p>We consider two illustrative innovations germane to healthcare delivery: one in medical education and one in technology. We try to anticipate and understand impacts and conclude by posing a set of questions that may be useful to those who manage systemic changes.</p><p>An innovation, unfolding in medical schools world-wide and often regarded as “transformative,” is competency-based medical education (CBME). We analyze this trend, relying on a hierarchy of knowledge as a frame of reference.</p><p>The historian Jill Lepore, using the metaphor of a filing cabinet with four drawers, proposed a categorization of knowledge [<span>3</span>]. Each drawer contains knowledge of a different ","PeriodicalId":100601,"journal":{"name":"Health Care Science","volume":"3 2","pages":"73-77"},"PeriodicalIF":0.0,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/hcs2.86","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140233516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Science, technology, and innovation in health for the next twenty years: A survey analysis in Colombia 未来二十年卫生领域的科学、技术和创新:哥伦比亚调查分析
Pub Date : 2024-03-18 DOI: 10.1002/hcs2.87
Oscar Espinosa, Gabriela Puentes, Jhonathan Rodríguez, Adriana Robayo, Juan-Manual Anaya

Background

Colombia is a Latin American country with a very complex social and political context that has not allowed the allocation of sufficient resources to the fields of science, technology, and innovation (STI). This is particularly worrying for the area of health since not enough resources are allocated for public health, research, or education.

Methods

The so-called “Great Survey in Health 2019” was administered online through the SurveyMonkey platform to 5298 people in different regions of the country, representing the public, private, and academic sectors. The questionnaire consisted of 46 open and closed questions, including demographic inquiries. Data analysis involved textual analytics and sentiment analysis.

Results

Overall, 56% of those surveyed were women within the adult life cycle. Most respondents had a postgraduate education. Greater participation was observed in the Oriental, Bogotá, and Antioquia regions, which also concentrate the largest number of resources for STI. Among the main recommendations derived from the results, priorities include investing in research, personalised medicine, promoting the social appropriation of knowledge, addressing mental health, regulating research through a statute, promoting undergraduate research, and establishing recertification exams to pursue excellence.

Conclusion

The results of this original study serve as a fundamental input to promote and strengthen the STI processes in life sciences and health. They serve as a guide to generate public policies and actions that guarantee better health and well-being for the Colombian population, strategically proposing a clear roadmap for the next 20 years.

哥伦比亚是一个社会和政治背景非常复杂的拉美国家,因此无法为科学、技术和创新(STI)领域分配足够的资源。所谓的 "2019 年健康大调查 "是通过 SurveyMonkey 平台对全国不同地区的 5298 名公共、私营和学术界代表进行的在线调查。问卷由 46 个开放式和封闭式问题组成,包括人口统计学调查。数据分析包括文本分析和情感分析。总体而言,56% 的受访者为成年女性。大多数受访者受过研究生教育。东方、波哥大和安蒂奥基亚地区的参与度更高,这些地区也集中了最多的科技创新资源。根据调查结果提出的主要建议中,优先事项包括投资于研究、个性化医疗、促进知识的社会占有、解决心理健康问题、通过法规规范研究、促进本科生研究以及设立再认证考试以追求卓越。这项原创性研究的成果为促进和加强生命科学与健康领域的科技创新进程提供了基本投入,也为制定公共政策和行动提供了指导,从而确保哥伦比亚人民享有更好的健康和福祉,并从战略高度为未来 20 年提出了明确的路线图。
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引用次数: 0
Machine learning in neurological disorders: A multivariate LSTM and AdaBoost approach to Alzheimer's disease time series analysis 神经系统疾病中的机器学习:阿尔茨海默病时间序列分析中的多元 LSTM 和 AdaBoost 方法
Pub Date : 2024-02-27 DOI: 10.1002/hcs2.84
Muhammad Irfan, Seyed Shahrestani, Mahmoud Elkhodr

Introduction

Alzheimer's disease (AD) is a progressive brain disorder that impairs cognitive functions, behavior, and memory. Early detection is crucial as it can slow down the progression of AD. However, early diagnosis and monitoring of AD's advancement pose significant challenges due to the necessity for complex cognitive assessments and medical tests.

Methods

This study introduces a data acquisition technique and a preprocessing pipeline, combined with multivariate long short-term memory (M-LSTM) and AdaBoost models. These models utilize biomarkers from cognitive assessments and neuroimaging scans to detect the progression of AD in patients, using The AD Prediction of Longitudinal Evolution challenge cohort from the Alzheimer's Disease Neuroimaging Initiative database.

Results

The methodology proposed in this study significantly improved performance metrics. The testing accuracy reached 80% with the AdaBoost model, while the M-LSTM model achieved an accuracy of 82%. This represents a 20% increase in accuracy compared to a recent similar study.

Discussion

The findings indicate that the multivariate model, specifically the M-LSTM, is more effective in identifying the progression of AD compared to the AdaBoost model and methodologies used in recent research.

导言 阿尔茨海默病(AD)是一种渐进性脑部疾病,会损害认知功能、行为和记忆。早期发现可以延缓阿尔茨海默病的进展,因此至关重要。然而,由于需要进行复杂的认知评估和医学测试,早期诊断和监测 AD 的进展带来了巨大挑战。 方法 本研究介绍了一种数据采集技术和预处理管道,并结合了多变量长短期记忆(M-LSTM)和 AdaBoost 模型。这些模型利用认知评估和神经影像扫描中的生物标记物,通过阿尔茨海默病神经影像倡议数据库中的 "纵向演化的AD预测挑战队列 "来检测患者的AD进展情况。 结果 本研究提出的方法显著提高了性能指标。AdaBoost 模型的测试准确率达到 80%,而 M-LSTM 模型的准确率达到 82%。与最近的一项类似研究相比,准确率提高了 20%。 讨论 研究结果表明,与 AdaBoost 模型和近期研究中使用的方法相比,多元模型,特别是 M-LSTM 在识别 AD 进展方面更为有效。
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引用次数: 0
Empowering health care innovations: A look forward into 2024 加强医疗保健创新:展望 2024 年
Pub Date : 2024-02-22 DOI: 10.1002/hcs2.85
Zongjiu Zhang, Tien Yin Wong, Haibo Wang, Jiefu Huang

As we unveil the first issue of Health Care Science in 2024, it's a moment of reflection and anticipation. Under the astute guidance of our leadership and the collective wisdom of our distinguished Editorial Board Members, we've journeyed through an extraordinary year, marking significant milestones and embracing challenges with resilience and innovation. We believe our progress reflects not just a testament to our commitment but also an indication of our role in driving healthcare innovation and excellence.

International diversity: 2023, our journal emerged as a vibrant international academic platform, attracting manuscripts from 29 countries and regions. Focusing on technological innovation in healthcare services, we published six issues of 39 articles in 2023, reaching over 41,000 downloads from 166 countries and regions. This diversity is a clear indicator of our expanding global footprint and the trust the academic community places in us. The growth in our publications, alongside a dramatic increase in international manuscript submissions, highlights our journal's rising stature on the global healthcare community.

Impactful publications: 2023 saw us publishing groundbreaking work in the fields of healthcare management, healthcare policy, medical technology, and public health. We also delved into hot topics like xenotransplantation, gene editing, and the application of large language models in healthcare. Moreover, we published influential guides and research on technological responses to pandemics. These contributions include some of our most downloaded and cited articles since the launch of Health Care Science.

Milestone recognitions: The landmark achievements in 2023 were our inclusion in prestigious databases such as Scopus and the Directory of Open Access Journals (DOAJ), a recognition that came just a year after our launch. These inclusions are not just an honor but a responsibility to uphold the standards of scientific excellence and accessibility.

Key metrics of publication process: We are pleased to share some key metrics regarding our manuscript process. Our median time to first decision was 24 days and the median time to final decision stood at 37 days, demonstrating our commitment to providing timely feedback to authors while also reflecting our thorough review process. Overall, our acceptance rate in 2023 was 54%. For those articles accepted, the median time from acceptance to online publication was 46 days. We are actively optimizing our publication cycle to enhance efficiency, while firmly safeguarding the rigor of the peer review process. Our emerging Associate Editor (eAE) team, composed of 21 dynamic young talents in academia, has been instrumental in manuscript sourcing, reviewing, curated readings, and promotions, significantly contributing to our journal's success.

Goals for 2024: Looking ahead, we aim to streamline our editorial process whi

当我们揭开《卫生保健科学》2024 年第一期的面纱时,这是一个充满反思和期待的时刻。在我们领导层的英明领导下,在我们杰出的编委会成员的集体智慧下,我们走过了不寻常的一年,见证了重要的里程碑,并以顽强的毅力和创新精神迎接挑战。我们相信,我们的进步不仅证明了我们的承诺,也表明了我们在推动医疗保健创新和卓越方面所发挥的作用。 国际多样性:2023 年,我们的期刊成为一个充满活力的国际学术平台,吸引了来自 29 个国家和地区的稿件。2023 年,我们出版了六期共 39 篇文章,重点关注医疗服务领域的技术创新,来自 166 个国家和地区的 41,000 多人次下载了这些文章。这种多样性清楚地表明了我们不断扩大的全球足迹以及学术界对我们的信任。我们出版物的增长以及国际投稿量的大幅增加,彰显了我们的期刊在全球医疗保健界不断提升的地位:2023 年,我们在医疗保健管理、医疗保健政策、医疗技术和公共卫生领域发表了开创性的工作。我们还深入研究了异种移植、基因编辑以及大型语言模型在医疗保健领域的应用等热门话题。此外,我们还出版了具有影响力的指南,并对大流行病的技术应对措施进行了研究。这些贡献包括我们自《医疗保健科学》创刊以来下载和引用次数最多的一些文章:2023 年的里程碑式成就是我们被 Scopus 和开放获取期刊目录(DOAJ)等著名数据库收录,这是在我们推出仅一年后获得的认可。这些收录不仅是一种荣誉,也是我们坚持科学卓越性和可获取性标准的责任:我们很高兴与大家分享一些有关我们稿件处理过程的关键指标。我们的初审时间中位数为 24 天,终审时间中位数为 37 天,这表明我们致力于为作者提供及时的反馈,同时也反映了我们全面的审稿流程。总体而言,我们在 2023 年的录用率为 54%。对于已录用的文章,从录用到在线发表的中位时间为 46 天。我们正在积极优化我们的出版周期,以提高效率,同时坚决维护同行评审过程的严谨性。我们的新兴副主编(eAE)团队由 21 位充满活力的学术界青年才俊组成,他们在稿件来源、审稿、策划阅读和推广方面发挥了重要作用,为期刊的成功做出了巨大贡献:展望未来,我们的目标是简化编辑流程,同时继续为作者提供全面的反馈。我们的首要任务是通过网络和面对面的方式与编委会和新晋编委会成员进行更密切的交流。此外,审稿人表彰计划的推出将表彰我们学术把关人的宝贵贡献,进一步提高我们出版流程的质量和效率:自《健康护理科学》创刊以来,我们一直致力于不仅仅是另一份医学期刊,而是一个促进医疗保健领域全面进步的平台。我们致力于推动技术创新、确保医疗质量、优先考虑患者安全以及提高医疗系统效率,这仍将是我们努力的动力。我们坚信,技术与医疗保健的协同作用将真正推动医疗保健科学的发展。欢迎来到充满可能性、创新和充满活力的卓越医疗保健年!主编张宗久,医学博士名誉主编黄洁夫,医学博士名誉主编尹黄天,医学博士执行主编王海波,医学博士、理学硕士、公共卫生硕士张宗久:构思(相同);撰写原稿(相同);审稿(相同)。Tien Yin Wong:构思(等同);审阅(等同);编辑(支持)。王海波构思(辅助);撰写原稿(等效);审阅(等效);编辑(主要)。黄洁夫:审稿(等同);编辑(支持)。作者声明无利益冲突。
{"title":"Empowering health care innovations: A look forward into 2024","authors":"Zongjiu Zhang,&nbsp;Tien Yin Wong,&nbsp;Haibo Wang,&nbsp;Jiefu Huang","doi":"10.1002/hcs2.85","DOIUrl":"https://doi.org/10.1002/hcs2.85","url":null,"abstract":"<p>As we unveil the first issue of <i>Health Care Science</i> in 2024, it's a moment of reflection and anticipation. Under the astute guidance of our leadership and the collective wisdom of our distinguished Editorial Board Members, we've journeyed through an extraordinary year, marking significant milestones and embracing challenges with resilience and innovation. We believe our progress reflects not just a testament to our commitment but also an indication of our role in driving healthcare innovation and excellence.</p><p><b>International diversity:</b> 2023, our journal emerged as a vibrant international academic platform, attracting manuscripts from 29 countries and regions. Focusing on technological innovation in healthcare services, we published six issues of 39 articles in 2023, reaching over 41,000 downloads from 166 countries and regions. This diversity is a clear indicator of our expanding global footprint and the trust the academic community places in us. The growth in our publications, alongside a dramatic increase in international manuscript submissions, highlights our journal's rising stature on the global healthcare community.</p><p><b>Impactful publications:</b> 2023 saw us publishing groundbreaking work in the fields of healthcare management, healthcare policy, medical technology, and public health. We also delved into hot topics like xenotransplantation, gene editing, and the application of large language models in healthcare. Moreover, we published influential guides and research on technological responses to pandemics. These contributions include some of our most downloaded and cited articles since the launch of <i>Health Care Science</i>.</p><p><b>Milestone recognitions:</b> The landmark achievements in 2023 were our inclusion in prestigious databases such as Scopus and the Directory of Open Access Journals (DOAJ), a recognition that came just a year after our launch. These inclusions are not just an honor but a responsibility to uphold the standards of scientific excellence and accessibility.</p><p><b>Key metrics of publication process:</b> We are pleased to share some key metrics regarding our manuscript process. Our median time to first decision was 24 days and the median time to final decision stood at 37 days, demonstrating our commitment to providing timely feedback to authors while also reflecting our thorough review process. Overall, our acceptance rate in 2023 was 54%. For those articles accepted, the median time from acceptance to online publication was 46 days. We are actively optimizing our publication cycle to enhance efficiency, while firmly safeguarding the rigor of the peer review process. Our emerging Associate Editor (eAE) team, composed of 21 dynamic young talents in academia, has been instrumental in manuscript sourcing, reviewing, curated readings, and promotions, significantly contributing to our journal's success.</p><p><b>Goals for 2024:</b> Looking ahead, we aim to streamline our editorial process whi","PeriodicalId":100601,"journal":{"name":"Health Care Science","volume":"3 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/hcs2.85","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139976501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of growth monitoring among children younger than 5 years at early childhood development centres in Nelson Mandela Bay, South Africa 评估南非纳尔逊-曼德拉湾幼儿发展中心 5 岁以下儿童的生长监测情况
Pub Date : 2024-02-05 DOI: 10.1002/hcs2.83
S. McLaren, Liana Steenkamp, Jessica Ronaasen
Early childhood development (ECD) centres are important community hubs in South Africa and act as sites for community detection of childhood nutrition problems. This study aimed to assess the ability of trained ECD practitioners with optimal support to correctly classify the nutritional status of infants and young children at ECD centres in the Nelson Mandela Bay.A descriptive, cross‐sectional study was used to collect data from 1645 infants and children at 88 ECD centres. Anthropometric measurements were taken by trained fieldworkers and growth monitoring and promotion infrastructure was audited at ECD centres.Of the sample, 4.4% (n = 72) were underweight by weight for age Z‐score (WAZ < −2) and 0.8% (n = 13) were severely underweight (WAZ < −3). Results showed that 13.1% (n = 214) were stunted by height for age Z‐score (HAZ < −2) and 4.5% (n = 74) were severely stunted (HAZ < −3). The prevalence of moderate acute malnutrition was 1.2% and severe acute malnutrition was 0.5%, while the prevalence of overweight was 9.2% and the prevalence of obesity was 4%. A significant level of agreement between the correct interpretation and the ECD practitioners' interpretation was observed across all the anthropometric indicators investigated. The true positive wasting cases had a mean mid‐upper arm circumference (MUAC) of 14.6 cm, which may explain the high false negative rate found in terms of children identified with wasting, where ECD practitioners fail to use the weight for height Z‐score (WHZ) interpretation for screening.By using ECD centres as hub to screen for malnutrition, it may contribute to the early identification of failure to thrive among young children. Although it was concerning that trained ECD practitioners are missing some children with an unacceptably high false negative rate, it may have been due to the fact that wasting in older children cannot be identified with MUAC alone and that accurate WFH plotting is needed. Onsite mentorship by governmental health workers may provide ECD practitioners with more confidence to screen children for growth failure based on regular WFH measurements. Moreover, ECD practitioners will be more confident to monitor the Road to Health booklets for missed vaccinations, vitamin A and deworming opportunities.
儿童早期发展(ECD)中心是南非重要的社区中心,也是社区发现儿童营养问题的场所。本研究旨在评估经过培训的幼儿发展从业人员在最佳支持下对纳尔逊-曼德拉湾幼儿发展中心的婴幼儿营养状况进行正确分类的能力。本研究采用描述性横断面研究方法,收集了 88 个幼儿发展中心 1645 名婴幼儿的数据。在样本中,4.4%(n = 72)的儿童体重不足(WAZ < -2),0.8%(n = 13)的儿童体重严重不足(WAZ < -3)。结果显示,按年龄 Z 值计算,13.1%(人数=214)的儿童身高发育迟缓(HAZ <-2),4.5%(人数=74)的儿童严重发育迟缓(HAZ <-3)。中度急性营养不良发生率为 1.2%,重度急性营养不良发生率为 0.5%,超重发生率为 9.2%,肥胖发生率为 4%。在所调查的所有人体测量指标中,正确解释与幼儿发展从业人员的解释之间的一致程度很高。真正的消瘦阳性病例的平均中上臂围(MUAC)为14.6厘米,这可能解释了为什么在幼儿发展从业人员未能使用体重身高Z值(WHZ)解释进行筛查的情况下,发现的消瘦儿童假阴性率很高。虽然令人担忧的是,经过培训的幼儿发展从业人员漏掉了一些儿童,假阴性率高得令人无法接受,但这可能是由于大龄儿童的消瘦不能仅通过 MUAC 来识别,还需要精确的 WFH 绘图。政府卫生工作者的现场指导可能会让幼儿发展从业人员更有信心根据定期测量的 WFH 值筛查儿童是否发育不良。此外,幼儿发展从业人员将更有信心监测《健康之路》手册,以发现错过接种疫苗、维生素 A 和驱虫机会的情况。
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引用次数: 0
Assessment of growth monitoring among children younger than 5 years at early childhood development centres in Nelson Mandela Bay, South Africa 评估南非纳尔逊-曼德拉湾幼儿发展中心 5 岁以下儿童的生长监测情况
Pub Date : 2024-02-05 DOI: 10.1002/hcs2.83
Shawn W. McLaren, Liana Steenkamp, Jessica Ronaasen

Introduction

Early childhood development (ECD) centres are important community hubs in South Africa and act as sites for community detection of childhood nutrition problems. This study aimed to assess the ability of trained ECD practitioners with optimal support to correctly classify the nutritional status of infants and young children at ECD centres in the Nelson Mandela Bay.

Methods

A descriptive, cross-sectional study was used to collect data from 1645 infants and children at 88 ECD centres. Anthropometric measurements were taken by trained fieldworkers and growth monitoring and promotion infrastructure was audited at ECD centres.

Results

Of the sample, 4.4% (n = 72) were underweight by weight for age Z-score (WAZ < −2) and 0.8% (n = 13) were severely underweight (WAZ < −3). Results showed that 13.1% (n = 214) were stunted by height for age Z-score (HAZ < −2) and 4.5% (n = 74) were severely stunted (HAZ < −3). The prevalence of moderate acute malnutrition was 1.2% and severe acute malnutrition was 0.5%, while the prevalence of overweight was 9.2% and the prevalence of obesity was 4%. A significant level of agreement between the correct interpretation and the ECD practitioners' interpretation was observed across all the anthropometric indicators investigated. The true positive wasting cases had a mean mid-upper arm circumference (MUAC) of 14.6 cm, which may explain the high false negative rate found in terms of children identified with wasting, where ECD practitioners fail to use the weight for height Z-score (WHZ) interpretation for screening.

Conclusion

By using ECD centres as hub to screen for malnutrition, it may contribute to the early identification of failure to thrive among young children. Although it was concerning that trained ECD practitioners are missing some children with an unacceptably high false negative rate, it may have been due to the fact that wasting in older children cannot be identified with MUAC alone and that accurate WFH plotting is needed. Onsite mentorship by governmental health workers may provide ECD practitioners with more confidence to screen children for growth failure based on regular WFH measurements. Moreover, ECD practitioners will be more confident to monitor the Road to Health booklets for missed vaccinations, vitamin A and deworming opportunities.

儿童早期发展(ECD)中心是南非重要的社区中心,也是社区发现儿童营养问题的场所。本研究旨在评估经过培训的幼儿发展从业人员在最佳支持下对纳尔逊-曼德拉湾幼儿发展中心的婴幼儿营养状况进行正确分类的能力。本研究采用描述性横断面研究方法,收集了 88 个幼儿发展中心 1645 名婴幼儿的数据。在样本中,4.4%(n = 72)的儿童体重不足(WAZ < -2),0.8%(n = 13)的儿童体重严重不足(WAZ < -3)。结果显示,按年龄 Z 值计算,13.1%(人数=214)的儿童身高发育迟缓(HAZ <-2),4.5%(人数=74)的儿童严重发育迟缓(HAZ <-3)。中度急性营养不良发生率为 1.2%,重度急性营养不良发生率为 0.5%,超重发生率为 9.2%,肥胖发生率为 4%。在所调查的所有人体测量指标中,正确解释与幼儿发展从业人员的解释之间的一致程度很高。真正的消瘦阳性病例的平均中上臂围(MUAC)为14.6厘米,这可能解释了为什么在幼儿发展从业人员未能使用体重身高Z值(WHZ)解释进行筛查的情况下,发现的消瘦儿童假阴性率很高。虽然令人担忧的是,经过培训的幼儿发展从业人员漏掉了一些儿童,假阴性率高得令人无法接受,但这可能是由于大龄儿童的消瘦不能仅通过 MUAC 来识别,还需要精确的 WFH 绘图。政府卫生工作者的现场指导可能会让幼儿发展从业人员更有信心根据定期测量的 WFH 值筛查儿童是否发育不良。此外,幼儿发展从业人员将更有信心监测《健康之路》手册,以发现错过接种疫苗、维生素 A 和驱虫机会的情况。
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引用次数: 0
Identifying a competency improvement strategy for infection prevention and control professionals: A rapid systematic review and cluster analysis 确定感染预防与控制专业人员的能力提升策略:快速系统回顾和聚类分析
Pub Date : 2024-02-04 DOI: 10.1002/hcs2.81
Nuo Chen, Shunning Li, Zhengling Kuang, Ting Gong, Weilong Zhou, Ying Wang

Remarkable progress has been made in infection prevention and control (IPC) in many countries, but some gaps emerged in the context of the coronavirus disease 2019 (COVID-19) pandemic. Core capabilities such as standard clinical precautions and tracing the source of infection were the focus of IPC in medical institutions during the pandemic. Therefore, the core competences of IPC professionals during the pandemic, and how these contributed to successful prevention and control of the epidemic, should be studied. To investigate, using a systematic review and cluster analysis, fundamental improvements in the competences of infection control and prevention professionals that may be emphasized in light of the COVID-19 pandemic. We searched the PubMed, Embase, Cochrane Library, Web of Science, CNKI, WanFang Data, and CBM databases for original articles exploring core competencies of IPC professionals during the COVID-19 pandemic (from January 1, 2020 to February 7, 2023). Weiciyun software was used for data extraction and the Donohue formula was followed to distinguish high-frequency technical terms. Cluster analysis was performed using the within-group linkage method and squared Euclidean distance as the metric to determine the priority competencies for development. We identified 46 studies with 29 high-frequency technical terms. The most common term was “infection prevention and control training” (184 times, 17.3%), followed by “hand hygiene” (172 times, 16.2%). “Infection prevention and control in clinical practice” was the most-reported core competency (367 times, 34.5%), followed by “microbiology and surveillance” (292 times, 27.5%). Cluster analysis showed two key areas of competence: Category 1 (program management and leadership, patient safety and occupational health, education and microbiology and surveillance) and Category 2 (IPC in clinical practice). During the COVID-19 pandemic, IPC program management and leadership, microbiology and surveillance, education, patient safety, and occupational health were the most important focus of development and should be given due consideration by IPC professionals.

许多国家在感染预防与控制(IPC)方面取得了显著进展,但在 2019 年冠状病毒病(COVID-19)大流行的背景下,出现了一些差距。在大流行期间,标准临床预防措施和追踪感染源等核心能力是医疗机构 IPC 的重点。因此,应研究大流行期间 IPC 专业人员的核心能力,以及这些能力如何有助于成功预防和控制疫情。通过系统综述和聚类分析,研究在 COVID-19 大流行期间,感染控制和预防专业人员在能力方面可能需要强调的基本改进。我们在 PubMed、Embase、Cochrane Library、Web of Science、CNKI、万方数据和 CBM 数据库中检索了探讨 COVID-19 大流行期间(2020 年 1 月 1 日至 2023 年 2 月 7 日)感染控制和预防专业人员核心能力的原创文章。使用织云软件进行数据提取,并采用多诺霍公式区分高频专业术语。采用组内关联法进行聚类分析,并以欧氏距离平方为指标来确定优先发展的能力。我们发现 46 项研究中有 29 个高频专业术语。最常见的术语是 "感染预防与控制培训"(184 次,17.3%),其次是 "手卫生"(172 次,16.2%)。"临床实践中的感染预防和控制 "是报告最多的核心能力(367 次,34.5%),其次是 "微生物学和监测"(292 次,27.5%)。聚类分析显示了两个关键的能力领域:第 1 类(项目管理和领导、患者安全和职业健康、教育以及微生物学和监测)和第 2 类(临床实践中的 IPC)。在 COVID-19 大流行期间,IPC 项目管理和领导、微生物学和监测、教育、患者安全和职业健康是最重要的发展重点,IPC 专业人员应予以充分考虑。
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