Pulmonary actinomycosis is difficult to diagnose, and many clinicians lack an understanding of the disease. Delayed diagnosis and misdiagnosis are common. Diffuse panbronchiolitis (DPB) is a rare clinical and pathologic syndrome that involves pulmonary bronchiolitis and chronic sinusitis. This report describes a case of DPB complicated with pulmonary actinomycosis. A 77-year-old Chinese male was admitted with complaints of chronic cough, expectoration, shortness of breath, and fever. He had a history of smoking, drinking, and dental caries. Chest examination revealed coarse crackles. Pulmonary function tests showed an obstructive defect. Computed tomography of the chest showed consolidation shadows, thickening and dilatation of bronchiolar walls, and diffuse central lobular nodules in both lungs. Histopathological examination of a surgical lung biopsy specimen confirmed DPB combined with actinomycosis. The patient's symptoms and radiological findings were significantly improved after penicillin combined with azithromycin therapy. Actinomycosis should be considered in older men who have structural lung diseases with recurrent lung infections. Early histological diagnosis and combination antibiotic therapy are very important in such patients.
{"title":"Coexistence of pulmonary actinomycosis with diffuse panbronchiolitis: A case report","authors":"Zhiguo Zhang, Ying Zhao, Hui Wang, Xiaoli Qi, Yongxiang Zhang","doi":"10.4103/rid.rid_3_23","DOIUrl":"https://doi.org/10.4103/rid.rid_3_23","url":null,"abstract":"Pulmonary actinomycosis is difficult to diagnose, and many clinicians lack an understanding of the disease. Delayed diagnosis and misdiagnosis are common. Diffuse panbronchiolitis (DPB) is a rare clinical and pathologic syndrome that involves pulmonary bronchiolitis and chronic sinusitis. This report describes a case of DPB complicated with pulmonary actinomycosis. A 77-year-old Chinese male was admitted with complaints of chronic cough, expectoration, shortness of breath, and fever. He had a history of smoking, drinking, and dental caries. Chest examination revealed coarse crackles. Pulmonary function tests showed an obstructive defect. Computed tomography of the chest showed consolidation shadows, thickening and dilatation of bronchiolar walls, and diffuse central lobular nodules in both lungs. Histopathological examination of a surgical lung biopsy specimen confirmed DPB combined with actinomycosis. The patient's symptoms and radiological findings were significantly improved after penicillin combined with azithromycin therapy. Actinomycosis should be considered in older men who have structural lung diseases with recurrent lung infections. Early histological diagnosis and combination antibiotic therapy are very important in such patients.","PeriodicalId":101055,"journal":{"name":"Radiology of Infectious Diseases","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135609448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
OBJECTIVE: To analyze the magnetic resonance imaging (MRI) manifestations of renal infection in children, evaluate the reliability of diffusion-weighted imaging (DWI) in detecting renal infections, and the difference in apparent diffusion coefficient (ADC) values between acute renal pelvis nephritis (APN), acute focal bacterial nephritis (AFBN) and renal abscess (RA). METHODS: Data for 513 children with a clinical orpathological diagnosis of acute kidney infection. Both MRI and voiding cystourethrography were performed in 28 cases. Group A comprised 17 cases of retrograde infection; Group B comprised 11 cases of blood–borne infection. The Kappa test was used to analyze differences in lesion DWI distribution between the groups, and the t-test was used to compare the ADC values. RESULTS: The MRI manifestations of pediatric renal infection were characteristic. The lesions had high-signal intensity on DWI and were located mainly in the renal cortex blood–borne infections versus the renal cortex and medulla in retrograde infections. The sensitivity and specificity of DWI for detecting lesions were 100% and 96%. The average ADC values of APN, AFBN, and RA lesions were lower than that of normal kidney tissue, with statistically significant differences between the three conditions; the ADC value of RA was the lowest, and that of APN was the highest. CONCLUSION: There were differences in the lesion distributions between renal retrograde and blood–borne infections. The quantitative decrease in ADC value may be related to the duration of the disease and the degree of renal damage.
{"title":"Magnetic resonance imaging diagnosis of renal infection in children","authors":"Huihui Lin, Xu Li, Xiaoyun Wang, Jun‐tao Hu, Chang Wang, Weimin Fei, Kaixuan Wang, Gengwu Li","doi":"10.4103/RID.RID_1_23","DOIUrl":"https://doi.org/10.4103/RID.RID_1_23","url":null,"abstract":"OBJECTIVE: To analyze the magnetic resonance imaging (MRI) manifestations of renal infection in children, evaluate the reliability of diffusion-weighted imaging (DWI) in detecting renal infections, and the difference in apparent diffusion coefficient (ADC) values between acute renal pelvis nephritis (APN), acute focal bacterial nephritis (AFBN) and renal abscess (RA). METHODS: Data for 513 children with a clinical orpathological diagnosis of acute kidney infection. Both MRI and voiding cystourethrography were performed in 28 cases. Group A comprised 17 cases of retrograde infection; Group B comprised 11 cases of blood–borne infection. The Kappa test was used to analyze differences in lesion DWI distribution between the groups, and the t-test was used to compare the ADC values. RESULTS: The MRI manifestations of pediatric renal infection were characteristic. The lesions had high-signal intensity on DWI and were located mainly in the renal cortex blood–borne infections versus the renal cortex and medulla in retrograde infections. The sensitivity and specificity of DWI for detecting lesions were 100% and 96%. The average ADC values of APN, AFBN, and RA lesions were lower than that of normal kidney tissue, with statistically significant differences between the three conditions; the ADC value of RA was the lowest, and that of APN was the highest. CONCLUSION: There were differences in the lesion distributions between renal retrograde and blood–borne infections. The quantitative decrease in ADC value may be related to the duration of the disease and the degree of renal damage.","PeriodicalId":101055,"journal":{"name":"Radiology of Infectious Diseases","volume":"27 1","pages":"6 - 11"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77107034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xiaoyan Xin, Wen Yang, Ying Wei, Jun Hu, Xin Peng, Yi Sun, Cong Long, Xin Zhang, Chao Du, F. Shi, Bing Zhang
OBJECTIVE: As hospital admission rate is high during the COVID-19 pandemic, hospital length of stay (LOS) is a key indicator of medical resource allocation. This study aimed to elucidate specific dynamic longitudinal computed tomography (CT) imaging changes for patients with COVID-19 over in-hospital and predict individual LOS of COVID-19 patients with Delta variant of SARS-CoV-2 using the machine learning method. MATERIALS AND METHODS: This retrospective study recruited 448 COVID-19 patients with a total of 1761 CT scans from July 14, 2021 to August 20, 2021 with an averaged hospital LOS of 22.5 ± 7.0 days. Imaging features were extracted from each CT scan, including CT morphological characteristics and artificial intelligence (AI) extracted features. Clinical features were obtained from each patient's initial admission. The infection distribution in lung fields and progression pattern tendency was analyzed. Then, to construct a model to predict patient LOS, each CT scan was considered as an independent sample to predict the LOS from the current CT scan time point to hospital discharge combining with the patients' corresponding clinical features. The 1761 follow-up CT data were randomly split into training set and testing set with a ratio of 7:3 at patient-level. A total of 85 most related clinical and imaging features selected by Least Absolute Shrinkage and Selection Operator were used to construct LOS prediction model. RESULTS: Infection-related features were obtained, such as the percentage of the infected region of lung, ground-glass opacity (GGO), consolidation and crazy-paving pattern, and air bronchograms. Their longitudinal changes show that the progression changes significantly in the earlier stages (0–3 days to 4–6 days), and then, changes tend to be statistically subtle, except for the intensity range between (−470 and −70) HU which exhibits a significant increase followed by a continuous significant decrease. Furthermore, the bilateral lower lobes, especially the right lower lobe, present more severe. Compared with other models, combining the clinical, imaging reading, and AI features to build the LOS prediction model achieved the highest R2 of 0.854 and 0.463, Pearson correlation coefficient of 0.939 and 0.696, and lowest mean absolute error of 2.405 and 4.426, and mean squared error of 9.176 and 34.728 on the training and testing set. CONCLUSION: The most obvious progression changes were significantly in the earlier stages (0–3 days to 4–6 days) and the bilateral lower lobes, especially the right lower lobe. GGO, consolidation, and crazy-paving pattern and air bronchograms are the most main CT findings according to the longitudinal changes of infection-related features with LOS (day). The LOS prediction model of combining clinical, imaging reading, and AI features achieved optimum performance.
{"title":"Dynamic chest computed tomography change analysis and prediction of length of stay for delta variant COVID-19 patients","authors":"Xiaoyan Xin, Wen Yang, Ying Wei, Jun Hu, Xin Peng, Yi Sun, Cong Long, Xin Zhang, Chao Du, F. Shi, Bing Zhang","doi":"10.4103/rid.rid_40_22","DOIUrl":"https://doi.org/10.4103/rid.rid_40_22","url":null,"abstract":"OBJECTIVE: As hospital admission rate is high during the COVID-19 pandemic, hospital length of stay (LOS) is a key indicator of medical resource allocation. This study aimed to elucidate specific dynamic longitudinal computed tomography (CT) imaging changes for patients with COVID-19 over in-hospital and predict individual LOS of COVID-19 patients with Delta variant of SARS-CoV-2 using the machine learning method. MATERIALS AND METHODS: This retrospective study recruited 448 COVID-19 patients with a total of 1761 CT scans from July 14, 2021 to August 20, 2021 with an averaged hospital LOS of 22.5 ± 7.0 days. Imaging features were extracted from each CT scan, including CT morphological characteristics and artificial intelligence (AI) extracted features. Clinical features were obtained from each patient's initial admission. The infection distribution in lung fields and progression pattern tendency was analyzed. Then, to construct a model to predict patient LOS, each CT scan was considered as an independent sample to predict the LOS from the current CT scan time point to hospital discharge combining with the patients' corresponding clinical features. The 1761 follow-up CT data were randomly split into training set and testing set with a ratio of 7:3 at patient-level. A total of 85 most related clinical and imaging features selected by Least Absolute Shrinkage and Selection Operator were used to construct LOS prediction model. RESULTS: Infection-related features were obtained, such as the percentage of the infected region of lung, ground-glass opacity (GGO), consolidation and crazy-paving pattern, and air bronchograms. Their longitudinal changes show that the progression changes significantly in the earlier stages (0–3 days to 4–6 days), and then, changes tend to be statistically subtle, except for the intensity range between (−470 and −70) HU which exhibits a significant increase followed by a continuous significant decrease. Furthermore, the bilateral lower lobes, especially the right lower lobe, present more severe. Compared with other models, combining the clinical, imaging reading, and AI features to build the LOS prediction model achieved the highest R2 of 0.854 and 0.463, Pearson correlation coefficient of 0.939 and 0.696, and lowest mean absolute error of 2.405 and 4.426, and mean squared error of 9.176 and 34.728 on the training and testing set. CONCLUSION: The most obvious progression changes were significantly in the earlier stages (0–3 days to 4–6 days) and the bilateral lower lobes, especially the right lower lobe. GGO, consolidation, and crazy-paving pattern and air bronchograms are the most main CT findings according to the longitudinal changes of infection-related features with LOS (day). The LOS prediction model of combining clinical, imaging reading, and AI features achieved optimum performance.","PeriodicalId":101055,"journal":{"name":"Radiology of Infectious Diseases","volume":"58 1","pages":"136 - 144"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84583864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hongmei Li, Hui Dai, R. Huang, Y. Shang, Jianan Huang, Daxiong Zeng, Weizhong Tian, Chunfeng Hu, Yonggang Li
Objectives: This study aimed to identify the clinical features of cardiac injury complicating with acute kidney injury (AKI) and its risk for a fatal outcome in patients infected with coronavirus disease 2019 (COVID-19) pneumonia. Methods: Initial signs and symptoms and clinical laboratory, radiological, and treatment information were obtained from seven hospitals in China from January 23, 2020, to March 15, 2020. Results: Of 438 patients, 36 (8.22%) displayed isolated cardiac injury, 17 (3.88%) had isolated AKI, and 17 (3.88%) displayed cardiac injury complicating with AKI. Compared with patients without cardiac injury or AKI, patients with isolated cardiac injury, isolated AKI, and cardiac injury complicating with AKI were older (55, 65, 74 vs. 48 years, P < 0.0001) and critically severe. More patients displayed fatigue, dyspnea, and comorbidities in the group with cardiac injury complicating with AKI. Moreover, the indexes reflecting myocardial, renal, liver, and coagulation dysfunctions and infection-related factors were significantly different among the four groups. After adjustment for covariates, patients with cardiac injury complicating with AKI had a higher hazard ratio for mortality (6.64; 95% confidence interval, 1.51–29.30). Conclusion: Cardiac injury complicating with kidney injury significantly increased the risk for in-hospital mortality in COVID-19 pneumonia patients. Therefore, early detection at admission and careful monitoring of myocardial and renal injury through biomarkers during hospitalization is recommended to reduce the harm to patients.
{"title":"Characteristics of cardiac injury complicating with acute kidney injury and mortality risk in coronavirus disease 2019 (COVID-19) patients","authors":"Hongmei Li, Hui Dai, R. Huang, Y. Shang, Jianan Huang, Daxiong Zeng, Weizhong Tian, Chunfeng Hu, Yonggang Li","doi":"10.4103/rid.rid_36_22","DOIUrl":"https://doi.org/10.4103/rid.rid_36_22","url":null,"abstract":"Objectives: This study aimed to identify the clinical features of cardiac injury complicating with acute kidney injury (AKI) and its risk for a fatal outcome in patients infected with coronavirus disease 2019 (COVID-19) pneumonia. Methods: Initial signs and symptoms and clinical laboratory, radiological, and treatment information were obtained from seven hospitals in China from January 23, 2020, to March 15, 2020. Results: Of 438 patients, 36 (8.22%) displayed isolated cardiac injury, 17 (3.88%) had isolated AKI, and 17 (3.88%) displayed cardiac injury complicating with AKI. Compared with patients without cardiac injury or AKI, patients with isolated cardiac injury, isolated AKI, and cardiac injury complicating with AKI were older (55, 65, 74 vs. 48 years, P < 0.0001) and critically severe. More patients displayed fatigue, dyspnea, and comorbidities in the group with cardiac injury complicating with AKI. Moreover, the indexes reflecting myocardial, renal, liver, and coagulation dysfunctions and infection-related factors were significantly different among the four groups. After adjustment for covariates, patients with cardiac injury complicating with AKI had a higher hazard ratio for mortality (6.64; 95% confidence interval, 1.51–29.30). Conclusion: Cardiac injury complicating with kidney injury significantly increased the risk for in-hospital mortality in COVID-19 pneumonia patients. Therefore, early detection at admission and careful monitoring of myocardial and renal injury through biomarkers during hospitalization is recommended to reduce the harm to patients.","PeriodicalId":101055,"journal":{"name":"Radiology of Infectious Diseases","volume":"42 1","pages":"111 - 118"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90196655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A patient with primary skeletal muscle lymphoma underwent plain and contrast-enhanced computed tomography (CT) and a pathologic diagnosis was made. The affected muscles were diffusely swollen, with recognizable outlines and clear borders. Contrast-enhanced CT showed mild-to-moderate enhancement, and the spaces surrounding the muscle and subcutaneous fat were narrowed and blurred. Primary skeletal muscle lymphoma is relatively rare and not very specific in its imaging manifestations. The final diagnosis depends on a biopsy of the lesion and immunohistochemistry.
{"title":"A case of primary soft-tissue lymphoma of the lower extremity complicated with bacterial infection in a patient with acquired immunodeficiency syndrome","authors":"Jingru Zhou, Yibo Lu","doi":"10.4103/rid.rid_29_22","DOIUrl":"https://doi.org/10.4103/rid.rid_29_22","url":null,"abstract":"A patient with primary skeletal muscle lymphoma underwent plain and contrast-enhanced computed tomography (CT) and a pathologic diagnosis was made. The affected muscles were diffusely swollen, with recognizable outlines and clear borders. Contrast-enhanced CT showed mild-to-moderate enhancement, and the spaces surrounding the muscle and subcutaneous fat were narrowed and blurred. Primary skeletal muscle lymphoma is relatively rare and not very specific in its imaging manifestations. The final diagnosis depends on a biopsy of the lesion and immunohistochemistry.","PeriodicalId":101055,"journal":{"name":"Radiology of Infectious Diseases","volume":"87 1","pages":"155 - 158"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89044077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Echinococcosis is a zoonotic parasitic disease caused by the larval stages of the Taeniid cestode species within the genus echinococcosis. The most commonly affected organ is the liver. Hepatic hydatid cysts have various complications, including superinfection and biliary, intrathoracic, and abdominal rupture. Intrabiliary rupture is the most common complication of hepatic hydatid cysts and is associated with high morbidity and mortality. Urgent imaging diagnosis and surgical management are required in these cases.
{"title":"Intrabiliary rupture of hepatic echinococcosis","authors":"S. Farooq, Wenya Liu","doi":"10.4103/rid.rid_46_22","DOIUrl":"https://doi.org/10.4103/rid.rid_46_22","url":null,"abstract":"Echinococcosis is a zoonotic parasitic disease caused by the larval stages of the Taeniid cestode species within the genus echinococcosis. The most commonly affected organ is the liver. Hepatic hydatid cysts have various complications, including superinfection and biliary, intrathoracic, and abdominal rupture. Intrabiliary rupture is the most common complication of hepatic hydatid cysts and is associated with high morbidity and mortality. Urgent imaging diagnosis and surgical management are required in these cases.","PeriodicalId":101055,"journal":{"name":"Radiology of Infectious Diseases","volume":"16 1","pages":"145 - 151"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74168636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Haixia Mao, J. Xu, Shengbin Gong, Hongwei Chen, Xiangming Fang
PURPOSE: The purpose of this study was to investigate the clinical and baseline computed tomography (CT) features and their correlation in patients infected with the B.1.617.2 (Delta) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). MATERIALS AND METHODS: Clinical and chest baseline CT data of patients infected with the Delta variant of SARS-CoV-2 from July to August 2021 were collected. First, the correlation between the clinical data and baseline CT results was analyzed according to CT positivity or negativity. Then, subgroup analysis was performed between different age distributions and clinical characteristics. Next, the CT characteristics and clinical data of all baseline CT-positive patients were collected, and the correlations between CT characteristics and age, vaccination status, and chronic disease were analyzed. Lesions in patients with baseline CT positivity were evaluated by semi-quantitative scoring to analyze the correlations between the semi-quantitative scores and vaccination status and age distribution. RESULTS: A total of 221 nucleic acid-positive patients with the SARS-CoV-2 Delta variant were included, of whom 107 patients were baseline CT positive and 114 were baseline CT negative. Baseline CT positivity was associated with age distribution, and baseline CT positivity was most common in patients aged >60 years (P < 0.001), but not with vaccination status or gender. The results of the subgroup analysis according to age distribution indicated that different age distribution subgroups had different vaccination statuses, and the majority of patients aged <18 years and >60 years were unvaccinated (90.5%, 19/21, and 57.3%, 63/110, respectively). In contrast, most patients aged 18–60 years had received two doses of the vaccine (61.1%, 55/90) (P < 0.001). Different age distribution subgroups had different clinical infection types. Asymptomatic and mild cases were most common in patients aged ≤60 years, and moderate and severe or critical cases were most common in patients aged >60 years. For baseline CT-positive patients, the extent of lung involvement was associated with age, vaccination status, and chronic disease. The number of involved lobes was higher in patients who were unvaccinated or who had received one injection, who were aged >60 years or had chronic disease. There was a statistical difference in CT semi-quantitative scores between the different age subgroups. Compared with patients aged < 60 years, patients aged >60 years had higher semi-quantitative scores (P < 0.001). However, there was no statistical difference between the different vaccination groups. CONCLUSIONS: Age had a large effect on baseline CT positivity, CT characteristics, and semi-quantitative CT scores in patients infected with the Delta variant.
{"title":"Clinical and baseline computed tomography features of patients infected with the B.1.617.2 (Delta) variant of severe acute respiratory syndrome coronavirus 2","authors":"Haixia Mao, J. Xu, Shengbin Gong, Hongwei Chen, Xiangming Fang","doi":"10.4103/rid.rid_35_22","DOIUrl":"https://doi.org/10.4103/rid.rid_35_22","url":null,"abstract":"PURPOSE: The purpose of this study was to investigate the clinical and baseline computed tomography (CT) features and their correlation in patients infected with the B.1.617.2 (Delta) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). MATERIALS AND METHODS: Clinical and chest baseline CT data of patients infected with the Delta variant of SARS-CoV-2 from July to August 2021 were collected. First, the correlation between the clinical data and baseline CT results was analyzed according to CT positivity or negativity. Then, subgroup analysis was performed between different age distributions and clinical characteristics. Next, the CT characteristics and clinical data of all baseline CT-positive patients were collected, and the correlations between CT characteristics and age, vaccination status, and chronic disease were analyzed. Lesions in patients with baseline CT positivity were evaluated by semi-quantitative scoring to analyze the correlations between the semi-quantitative scores and vaccination status and age distribution. RESULTS: A total of 221 nucleic acid-positive patients with the SARS-CoV-2 Delta variant were included, of whom 107 patients were baseline CT positive and 114 were baseline CT negative. Baseline CT positivity was associated with age distribution, and baseline CT positivity was most common in patients aged >60 years (P < 0.001), but not with vaccination status or gender. The results of the subgroup analysis according to age distribution indicated that different age distribution subgroups had different vaccination statuses, and the majority of patients aged <18 years and >60 years were unvaccinated (90.5%, 19/21, and 57.3%, 63/110, respectively). In contrast, most patients aged 18–60 years had received two doses of the vaccine (61.1%, 55/90) (P < 0.001). Different age distribution subgroups had different clinical infection types. Asymptomatic and mild cases were most common in patients aged ≤60 years, and moderate and severe or critical cases were most common in patients aged >60 years. For baseline CT-positive patients, the extent of lung involvement was associated with age, vaccination status, and chronic disease. The number of involved lobes was higher in patients who were unvaccinated or who had received one injection, who were aged >60 years or had chronic disease. There was a statistical difference in CT semi-quantitative scores between the different age subgroups. Compared with patients aged < 60 years, patients aged >60 years had higher semi-quantitative scores (P < 0.001). However, there was no statistical difference between the different vaccination groups. CONCLUSIONS: Age had a large effect on baseline CT positivity, CT characteristics, and semi-quantitative CT scores in patients infected with the Delta variant.","PeriodicalId":101055,"journal":{"name":"Radiology of Infectious Diseases","volume":"76 1","pages":"119 - 125"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87050670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Osteomyelitis of the maxilla with orbital cellulitis, an uncommon and life-threatening disease, can be misdiagnosed. We here report a 13-year-old boy, possibly with combined immunodeficiency disease, who presented with osteomyelitis of the maxilla and orbital cellulitis after tooth extraction. Computed tomography demonstrated thickening of the left maxillary bone. Magnetic resonance imaging showed inflammation in the left maxillary bone and retrobulbar space. Metagenomic analysis of an aspiration biopsy resulted in a diagnosis of infection with Porphyromonas endodontalis. He was successfully treated with metronidazole.
{"title":"Osteomyelitis of maxilla with orbital cellulitis after tooth extraction","authors":"Q. Yao, Xi-hong Hu","doi":"10.4103/rid.rid_16_22","DOIUrl":"https://doi.org/10.4103/rid.rid_16_22","url":null,"abstract":"Osteomyelitis of the maxilla with orbital cellulitis, an uncommon and life-threatening disease, can be misdiagnosed. We here report a 13-year-old boy, possibly with combined immunodeficiency disease, who presented with osteomyelitis of the maxilla and orbital cellulitis after tooth extraction. Computed tomography demonstrated thickening of the left maxillary bone. Magnetic resonance imaging showed inflammation in the left maxillary bone and retrobulbar space. Metagenomic analysis of an aspiration biopsy resulted in a diagnosis of infection with Porphyromonas endodontalis. He was successfully treated with metronidazole.","PeriodicalId":101055,"journal":{"name":"Radiology of Infectious Diseases","volume":"123 1","pages":"152 - 154"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85682863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hui Dai, R. Huang, Y. Shang, Jianan Huang, N. Su, D. Zeng, Hongmei Li, Yonggang Li
BACKGROUND: Coronavirus Disease 2019 (COVID-19) is currently a global pandemic. Information about predicting mortality in severe COVID-19 remains unclear. METHODS: A total of 151 COVID-19 in-patients from January 23 to March 8, 2020, were divided into severe and critically severe groups and survival and mortality groups. Differences in the clinical and imaging data between the groups were analyzed. Factors associated with COVID-19 mortality were analyzed by logistic regression, and a mortality prediction model was developed. RESULTS: Many clinical and imaging indices were significantly different between groups, including age, epidemic history, medical history, duration of symptoms before admission, routine blood parameters, inflammatory-related factors, Na+, myocardial zymogram, liver and renal function, coagulation function, fraction of inspired oxygen and complications. The proportions of patients with imaging Stage III and a comprehensive computed tomography score were significantly increased in the mortality group. Factors in the prediction model included patient age, cardiac injury, acute kidney injury, and acute respiratory distress syndrome. The area under the receiver operating characteristic curve of the prediction model was 0.9593. CONCLUSIONS: The clinical and imaging data reflected the severity of COVID-19 pneumonia. The mortality prediction model might be a promising method to help clinicians quickly identify COVID-19 patients who are at high risk of death.
{"title":"Mortality risk analysis for patients with severe coronavirus disease 2019 pneumonia","authors":"Hui Dai, R. Huang, Y. Shang, Jianan Huang, N. Su, D. Zeng, Hongmei Li, Yonggang Li","doi":"10.4103/rid.rid_44_22","DOIUrl":"https://doi.org/10.4103/rid.rid_44_22","url":null,"abstract":"BACKGROUND: Coronavirus Disease 2019 (COVID-19) is currently a global pandemic. Information about predicting mortality in severe COVID-19 remains unclear. METHODS: A total of 151 COVID-19 in-patients from January 23 to March 8, 2020, were divided into severe and critically severe groups and survival and mortality groups. Differences in the clinical and imaging data between the groups were analyzed. Factors associated with COVID-19 mortality were analyzed by logistic regression, and a mortality prediction model was developed. RESULTS: Many clinical and imaging indices were significantly different between groups, including age, epidemic history, medical history, duration of symptoms before admission, routine blood parameters, inflammatory-related factors, Na+, myocardial zymogram, liver and renal function, coagulation function, fraction of inspired oxygen and complications. The proportions of patients with imaging Stage III and a comprehensive computed tomography score were significantly increased in the mortality group. Factors in the prediction model included patient age, cardiac injury, acute kidney injury, and acute respiratory distress syndrome. The area under the receiver operating characteristic curve of the prediction model was 0.9593. CONCLUSIONS: The clinical and imaging data reflected the severity of COVID-19 pneumonia. The mortality prediction model might be a promising method to help clinicians quickly identify COVID-19 patients who are at high risk of death.","PeriodicalId":101055,"journal":{"name":"Radiology of Infectious Diseases","volume":"82 ","pages":"126 - 135"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91452811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Haijun He, Xiao Chen, Qiuyuan Yang, Z. Peng, Caiqiong Wang, Tengfei Ke, Zhengyu Liu, Bin Yang
Pulmonary hydatid disease is a helminthic zoonotic disease caused by Echinococcus infection. The symptoms may appear several years after infection. Chest computed tomography (CT) is the preferred examination method and plays an important role in early diagnosis, treatment, and prognosis evaluation. CT can be used to diagnose simple cystic lesions. However, when the cysts are infected or ruptured, atypical imaging findings such as increased cyst density, blurring of the cyst wall, and surrounding exudation may lead to misdiagnosis of lung infection or lung abscess, hindering the therapeutic effect. We analyzed and compared the atypical imaging manifestations of pulmonary simple hydatid disease and hydatid cyst rupture. The aims of this report are to improve clinicians' understanding of these diseases, promote early diagnosis and treatment, and reduce the occurrence of complications.
{"title":"Computed tomography diagnosis of pulmonary hydatid disease","authors":"Haijun He, Xiao Chen, Qiuyuan Yang, Z. Peng, Caiqiong Wang, Tengfei Ke, Zhengyu Liu, Bin Yang","doi":"10.4103/rid.rid_25_22","DOIUrl":"https://doi.org/10.4103/rid.rid_25_22","url":null,"abstract":"Pulmonary hydatid disease is a helminthic zoonotic disease caused by Echinococcus infection. The symptoms may appear several years after infection. Chest computed tomography (CT) is the preferred examination method and plays an important role in early diagnosis, treatment, and prognosis evaluation. CT can be used to diagnose simple cystic lesions. However, when the cysts are infected or ruptured, atypical imaging findings such as increased cyst density, blurring of the cyst wall, and surrounding exudation may lead to misdiagnosis of lung infection or lung abscess, hindering the therapeutic effect. We analyzed and compared the atypical imaging manifestations of pulmonary simple hydatid disease and hydatid cyst rupture. The aims of this report are to improve clinicians' understanding of these diseases, promote early diagnosis and treatment, and reduce the occurrence of complications.","PeriodicalId":101055,"journal":{"name":"Radiology of Infectious Diseases","volume":"7 1","pages":"104 - 107"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79018083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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