Parasites are an important cause of human diseases. With the increase in global population migration, the decline of population immunity, and changes in living habits, parasitic diseases have been increasing year by year. Because the liver has a unique blood supply system and a biliary system that communicates with the intestinal tract, it is relatively more vulnerable to a variety of parasitic infections. Imaging examinations play an important role in the early detection, characterization, evaluation, and treatment of hepatic parasitic diseases. Various imaging methods can not only detect hepatic parasitic diseases accurately but also evaluate liver injury, liver fibrosis, abnormal blood perfusion, metabolic changes, and malignant tumors caused by parasitic infection. Familiarity with the imaging features of hepatic parasitic diseases is helpful for the early diagnosis and treatment. This article reviews the progress in imaging research on common hepatic parasitic diseases.
{"title":"Hepatic parasitic diseases − state of the art: Imaging study","authors":"Y. Xiang, Ningqin Li, Jin-yuan Liao","doi":"10.4103/rid.rid_27_21","DOIUrl":"https://doi.org/10.4103/rid.rid_27_21","url":null,"abstract":"Parasites are an important cause of human diseases. With the increase in global population migration, the decline of population immunity, and changes in living habits, parasitic diseases have been increasing year by year. Because the liver has a unique blood supply system and a biliary system that communicates with the intestinal tract, it is relatively more vulnerable to a variety of parasitic infections. Imaging examinations play an important role in the early detection, characterization, evaluation, and treatment of hepatic parasitic diseases. Various imaging methods can not only detect hepatic parasitic diseases accurately but also evaluate liver injury, liver fibrosis, abnormal blood perfusion, metabolic changes, and malignant tumors caused by parasitic infection. Familiarity with the imaging features of hepatic parasitic diseases is helpful for the early diagnosis and treatment. This article reviews the progress in imaging research on common hepatic parasitic diseases.","PeriodicalId":101055,"journal":{"name":"Radiology of Infectious Diseases","volume":"229 1","pages":"116 - 121"},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75794332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The COVID-19 pandemic has created worldwide change in screening, management, and deadlines for the treatment of tuberculosis, among other latent diseases. Safe access to health-care structures, drug interactions, and ongoing changes in treatment guidelines are the main challenges. The first published cohort of 45 patients with both tuberculosis and SARS-CoV-2 infection presented three different scenarios regarding the timing of these diagnoses, both diagnoses being made within the same week in only nine of these patients. Thus far, tuberculosis has not been shown to influence the pathophysiology of SARS-CoV-2 infection. The association between these two diseases may be incidental. Tuberculosis remains the leading lethal infection worldwide. 2In patients with preexisting pulmonary tuberculosis and COVID-19, management priorities, drug interactions, and optimal frequency of clinical, biological, and radiological check-ups require clarification. We here report an asymptomatic young patient who had both COVID-19 and pulmonary tuberculosis, raising challenging questions regarding diagnostic tools, treatment, and follow-up.
{"title":"Fortuitous discovery of pulmonary tuberculosis in an asymptomatic, SARS-CoV-2 positive, Moroccan patient","authors":"K. Cherrabi, N. Benmansour, N. El Alami","doi":"10.4103/rid.rid_8_22","DOIUrl":"https://doi.org/10.4103/rid.rid_8_22","url":null,"abstract":"The COVID-19 pandemic has created worldwide change in screening, management, and deadlines for the treatment of tuberculosis, among other latent diseases. Safe access to health-care structures, drug interactions, and ongoing changes in treatment guidelines are the main challenges. The first published cohort of 45 patients with both tuberculosis and SARS-CoV-2 infection presented three different scenarios regarding the timing of these diagnoses, both diagnoses being made within the same week in only nine of these patients. Thus far, tuberculosis has not been shown to influence the pathophysiology of SARS-CoV-2 infection. The association between these two diseases may be incidental. Tuberculosis remains the leading lethal infection worldwide. 2In patients with preexisting pulmonary tuberculosis and COVID-19, management priorities, drug interactions, and optimal frequency of clinical, biological, and radiological check-ups require clarification. We here report an asymptomatic young patient who had both COVID-19 and pulmonary tuberculosis, raising challenging questions regarding diagnostic tools, treatment, and follow-up.","PeriodicalId":101055,"journal":{"name":"Radiology of Infectious Diseases","volume":"64 1","pages":"125 - 129"},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88889501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Despite global efforts to eradicate tuberculosis (TB), 10 million new cases are reported each year. Indigenous communities are at greater risk of developing TB. We report a 7-year-old indigenous boy who presented with neurological symptoms. An intracranial neoplasm was suspected based on imaging findings and he underwent neurosurgical resection. The final diagnosis was intracranial tuberculoma. Anti-TB therapy was administered and the patient recovered completely.
{"title":"Brain tuberculoma in a Colombian indigenous child","authors":"L. Jurado, Víctor Hernández-Gómez, Jaime Arias","doi":"10.4103/rid.rid_9_22","DOIUrl":"https://doi.org/10.4103/rid.rid_9_22","url":null,"abstract":"Despite global efforts to eradicate tuberculosis (TB), 10 million new cases are reported each year. Indigenous communities are at greater risk of developing TB. We report a 7-year-old indigenous boy who presented with neurological symptoms. An intracranial neoplasm was suspected based on imaging findings and he underwent neurosurgical resection. The final diagnosis was intracranial tuberculoma. Anti-TB therapy was administered and the patient recovered completely.","PeriodicalId":101055,"journal":{"name":"Radiology of Infectious Diseases","volume":"4 1","pages":"122 - 124"},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73627931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical and imaging characteristics of mycotic aortic aneurysm caused by Klebsiella pneumonia","authors":"Jingyi Cheng, Yu Li, Jin Cheng, N. Hong","doi":"10.4103/rid.rid_22_21","DOIUrl":"https://doi.org/10.4103/rid.rid_22_21","url":null,"abstract":"","PeriodicalId":101055,"journal":{"name":"Radiology of Infectious Diseases","volume":"41 1","pages":"92 - 94"},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83545712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pulmonary infective diseases with high morbidity and mortality have contributed significantly to the socioeconomic burden worldwide. Despite advances in the technology for identification of pathogenic microorganisms, increased diagnostic accuracy for noninfectious pulmonary inflammation, and the availability of effectively individualized therapy, a major concern is the lack of optimal diagnostic approaches and biomarkers for the early stages of infectious disease. Radiomics, a concept first proposed in 2012, is a process that can extract quantitative features and high-dimensional data from digital medical images such as conventional chest X-ray, computed tomography (CT), magnetic resonance imaging, positron emission tomography, and single-photon emission CT. The high-dimensional data and mineable features can be utilized to build descriptive and predictive models to quantify the inflammatory burden on the lung and understand lung function. Overall, radiomics now plays an important role in the clinical diagnosis and treatment of pulmonary infection, with medical imaging being routinely applied in the clinical workup of pneumonia. Radiomics may also provide an opportunity to allow accurate diagnosis of pulmonary infection in the early stages, thereby decreasing mortality at a low cost.
{"title":"Radiomics applied to pulmonary infection: A review","authors":"Li-Li Zuo, Zengzhuang Wang, Dexin Yu","doi":"10.4103/rid.rid_15_21","DOIUrl":"https://doi.org/10.4103/rid.rid_15_21","url":null,"abstract":"Pulmonary infective diseases with high morbidity and mortality have contributed significantly to the socioeconomic burden worldwide. Despite advances in the technology for identification of pathogenic microorganisms, increased diagnostic accuracy for noninfectious pulmonary inflammation, and the availability of effectively individualized therapy, a major concern is the lack of optimal diagnostic approaches and biomarkers for the early stages of infectious disease. Radiomics, a concept first proposed in 2012, is a process that can extract quantitative features and high-dimensional data from digital medical images such as conventional chest X-ray, computed tomography (CT), magnetic resonance imaging, positron emission tomography, and single-photon emission CT. The high-dimensional data and mineable features can be utilized to build descriptive and predictive models to quantify the inflammatory burden on the lung and understand lung function. Overall, radiomics now plays an important role in the clinical diagnosis and treatment of pulmonary infection, with medical imaging being routinely applied in the clinical workup of pneumonia. Radiomics may also provide an opportunity to allow accurate diagnosis of pulmonary infection in the early stages, thereby decreasing mortality at a low cost.","PeriodicalId":101055,"journal":{"name":"Radiology of Infectious Diseases","volume":"50 1 1","pages":"77 - 84"},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89208865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Esra Erdil, H. Tunç, O. Alhan, L. Mulazımoglu, P. Koytak, I. Midi
{"title":"A case of rhinocerebral mucormycosis presenting orbital apex syndrome","authors":"Esra Erdil, H. Tunç, O. Alhan, L. Mulazımoglu, P. Koytak, I. Midi","doi":"10.4103/RID.RID_20_21","DOIUrl":"https://doi.org/10.4103/RID.RID_20_21","url":null,"abstract":"","PeriodicalId":101055,"journal":{"name":"Radiology of Infectious Diseases","volume":"16 1","pages":"89 - 91"},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78526865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
OBJECTIVE: The objective of the study is to retrospectively investigate the magnetic resonance imaging (MRI) features of recurrent spinal hydatidosis and distinguish the MRI features between recurrent spinal hydatidosis and primary spinal hydatidosis. MATERIALS AND METHODS: Nineteen patients with spinal hydatidosis disease who underwent surgery and pathological diagnosis from July 2014 to January 2018 were selected. Nine cases recurred postoperatively and had complete imaging and clinical data. RESULTS: Compared with the MRI features of primary spinal hydatidosis, the MRI features of postoperative recurrence of spinal hydatidosis were as follows: most of the typical features of the primary lesion disappeared, with no obvious outer membrane wrapped around the lesion, and high-intensity signal “small vesicles” were seen on T2-weighted image (T2WI). Most vesicles had no obvious “grape-bunch”-like change and no typical polycystic structures. The vertebral bone destruction area and surrounding soft tissue structures were unclear, and there was no low-signal arc-like calcification on T1WI and T2WI. Recurrent lesions usually appeared as multiple lesions with significant distance from each other, and single clusters formed by multiple lesions were uncommon. Intervertebral disc involvement is a long-term destructive feature. CONCLUSION: Postoperative recurrence of spinal hydatidosis has prominent MRI features, which can provide a more comprehensive and reliable imaging diagnosis basis for postoperative recurrence of spinal hydatidosis.
{"title":"Magnetic resonance imaging features of recurrent spinal hydatidosis","authors":"Fei Wang, Jinying Wang, Hui Tian, Xin Gao, Hui Xing, Jian Wang","doi":"10.4103/rid.rid_16_21","DOIUrl":"https://doi.org/10.4103/rid.rid_16_21","url":null,"abstract":"OBJECTIVE: The objective of the study is to retrospectively investigate the magnetic resonance imaging (MRI) features of recurrent spinal hydatidosis and distinguish the MRI features between recurrent spinal hydatidosis and primary spinal hydatidosis. MATERIALS AND METHODS: Nineteen patients with spinal hydatidosis disease who underwent surgery and pathological diagnosis from July 2014 to January 2018 were selected. Nine cases recurred postoperatively and had complete imaging and clinical data. RESULTS: Compared with the MRI features of primary spinal hydatidosis, the MRI features of postoperative recurrence of spinal hydatidosis were as follows: most of the typical features of the primary lesion disappeared, with no obvious outer membrane wrapped around the lesion, and high-intensity signal “small vesicles” were seen on T2-weighted image (T2WI). Most vesicles had no obvious “grape-bunch”-like change and no typical polycystic structures. The vertebral bone destruction area and surrounding soft tissue structures were unclear, and there was no low-signal arc-like calcification on T1WI and T2WI. Recurrent lesions usually appeared as multiple lesions with significant distance from each other, and single clusters formed by multiple lesions were uncommon. Intervertebral disc involvement is a long-term destructive feature. CONCLUSION: Postoperative recurrence of spinal hydatidosis has prominent MRI features, which can provide a more comprehensive and reliable imaging diagnosis basis for postoperative recurrence of spinal hydatidosis.","PeriodicalId":101055,"journal":{"name":"Radiology of Infectious Diseases","volume":"155 1","pages":"65 - 68"},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79785690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lanfu Wu, Ran Yang, D. Guo, Xiang Li, Chuanming Li, W. Zeng, Ting Chen
OBJECTIVE: To quantitatively analyze the longitudinal changes of ground-glass opacity (GGO), consolidation and total lesion in patients infected with severe coronavirus disease 2019 (COVID-19), and its correlation with laboratory examination results. MATERIALS AND METHODS: All 76 computed tomography (CT) images and laboratory examination results from the admission to discharge of 15 patients confirmed with severe COVID-19 were reviewed, whereas the GGO volume ratio, consolidation volume ratio, and total lesion volume ratio in different stages were analyzed. The correlations of lesions volume ratio and laboratory examination results were investigated. RESULTS: Four stages were identified based on the degree of lung involvement from day 1 to day 28 after disease onset. GGO was the most common CT manifestation in the four stages. The peak of lung involvement was at around stage 2, and corresponding total lesion volume ratio, GGO volume ratio, and consolidation volume ratio were 17.48 (13.44−24.33), 12.11 (7.34−17.08), and 5.51 (2.58−8.58), respectively. Total lesion volume ratio was positively correlated with neutrophil percentage, C-reactive protein (CRP), high-sensitivity CRP (Hs-CRP), procalcitonin, lactate dehydrogenase (LD), and creatine kinase isoenzyme MB (CK-MB), but negatively correlated with lymphocyte count, lymphocyte percentage, arterial oxygen saturation, and arterial oxygen tension. Consolidation volume ratio was correlated with most above laboratory examination results except Hs-CRP, LD, and CK-MB. GGO, however, was only correlated with lymphocyte count. CONCLUSION: CT quantitative parameters could show longitudinal changes well. Total lesion volume ratio and consolidation volume ratio are well correlated with laboratory examination results, suggesting that CT quantitative parameters may be an effective tool to reflect the changes in the condition.
{"title":"CT quantitative analysis in patients with severe coronavirus disease 2019 and its correlation with laboratory examination results","authors":"Lanfu Wu, Ran Yang, D. Guo, Xiang Li, Chuanming Li, W. Zeng, Ting Chen","doi":"10.4103/RID.RID_3_21","DOIUrl":"https://doi.org/10.4103/RID.RID_3_21","url":null,"abstract":"OBJECTIVE: To quantitatively analyze the longitudinal changes of ground-glass opacity (GGO), consolidation and total lesion in patients infected with severe coronavirus disease 2019 (COVID-19), and its correlation with laboratory examination results. MATERIALS AND METHODS: All 76 computed tomography (CT) images and laboratory examination results from the admission to discharge of 15 patients confirmed with severe COVID-19 were reviewed, whereas the GGO volume ratio, consolidation volume ratio, and total lesion volume ratio in different stages were analyzed. The correlations of lesions volume ratio and laboratory examination results were investigated. RESULTS: Four stages were identified based on the degree of lung involvement from day 1 to day 28 after disease onset. GGO was the most common CT manifestation in the four stages. The peak of lung involvement was at around stage 2, and corresponding total lesion volume ratio, GGO volume ratio, and consolidation volume ratio were 17.48 (13.44−24.33), 12.11 (7.34−17.08), and 5.51 (2.58−8.58), respectively. Total lesion volume ratio was positively correlated with neutrophil percentage, C-reactive protein (CRP), high-sensitivity CRP (Hs-CRP), procalcitonin, lactate dehydrogenase (LD), and creatine kinase isoenzyme MB (CK-MB), but negatively correlated with lymphocyte count, lymphocyte percentage, arterial oxygen saturation, and arterial oxygen tension. Consolidation volume ratio was correlated with most above laboratory examination results except Hs-CRP, LD, and CK-MB. GGO, however, was only correlated with lymphocyte count. CONCLUSION: CT quantitative parameters could show longitudinal changes well. Total lesion volume ratio and consolidation volume ratio are well correlated with laboratory examination results, suggesting that CT quantitative parameters may be an effective tool to reflect the changes in the condition.","PeriodicalId":101055,"journal":{"name":"Radiology of Infectious Diseases","volume":"125 1","pages":"17 - 24"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90594288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ruken Ergenc, Deniz Okray, U. Mutlu, A. Tanyeri, M. Şahin
OBJECTIVE: We investigated the correlation between computed tomography (CT) scores, laboratory findings, and clinical symptoms in patients with coronavirus disease 2019 (COVID-19). MATERIALS AND METHODS: Clinical, laboratory, and thorax CT findings on the admission of 121 patients with COVID-19 were retrospectively evaluated. CT scores based on lobe involvement and CT patterns (i.e., ground-glass abnormalities, consolidation, and crazy-paving patterns) were estimated, and the relationship between CT score and symptomatic (e.g. fever, cough) versus asymptomatic (e.g., inflammation, coagulation, liver and kidney function) clinical laboratory findings were statistically analyzed. RESULTS: Sixty-eight of 121 patients (56%) were symptomatic; 53 (44%) were asymptomatic. The CT scores of symptomatic patients, especially those with coughing and dyspnea, were statistically higher (2 [0–9] vs. 0 [0–1]; P < 0.001). Erythrocyte sedimentation rate, C-reactive protein, ferritin, D-dimer, fibrinogen, aspartate aminotransferase, lactate dehydrogenase, glucose, prothrombin time and alanine amino transferase values were correlated with CT scores (ρ = 0.638, P < 0.001, ρ = 0.512, P < 0.001; ρ = 0.325, P = 0.001; ρ = 0.452, P < 0.001; ρ = 0.525, P < 0.001; ρ = 0.379, P < 0.001; ρ = 0.445, P < 0.001; ρ = 0.332, P < 0.001, ρ = 0.296, P = 0.003; ρ = 0.222, P = 0.015, respectively). Albumin values were negatively correlated with CT scores (ρ = −0.398, P < 0.001). CONCLUSION: CT scores may help clinicians evaluate the severity of COVID-19 pneumonia and thus help in managing the disease.
目的:探讨2019冠状病毒病(COVID-19)患者计算机断层扫描(CT)评分、实验室检查结果与临床症状的相关性。材料与方法:回顾性分析121例新冠肺炎患者入院时的临床、实验室和胸部CT表现。根据肺叶受累程度和CT表现(如磨玻璃异常、实变和疯狂铺路表现)估计CT评分，并统计分析CT评分与有症状(如发热、咳嗽)和无症状(如炎症、凝血、肝肾功能)临床实验室表现的关系。结果:121例患者中有68例(56%)出现症状;53例(44%)无症状。有症状的患者，特别是咳嗽、呼吸困难患者的CT评分有统计学意义(2 [0 - 9]vs. 0 [0 - 1]);P < 0.001)。红细胞沉降率、c反应蛋白、铁蛋白、d -二聚体、纤维蛋白原、天冬氨酸转氨酶、乳酸脱氢酶、葡萄糖、凝血酶原时间、丙氨酸氨基转移酶值与CT评分相关(ρ = 0.638, P < 0.001， ρ = 0.512, P < 0.001;ρ = 0.325, p = 0.001;ρ = 0.452, p < 0.001;ρ = 0.525, p < 0.001;ρ = 0.379, p < 0.001;ρ = 0.445, p < 0.001;ρ = 0.332, p < 0.001， ρ = 0.296, p = 0.003;ρ = 0.222, P = 0.015)。白蛋白值与CT评分呈负相关(ρ = - 0.398, P < 0.001)。结论:CT评分可以帮助临床医生评估COVID-19肺炎的严重程度，从而有助于疾病的控制。
{"title":"Correlation between thorax computed tomography findings and clinical and laboratory data on patients with coronavirus disease 2019","authors":"Ruken Ergenc, Deniz Okray, U. Mutlu, A. Tanyeri, M. Şahin","doi":"10.4103/RID.RID_2_21","DOIUrl":"https://doi.org/10.4103/RID.RID_2_21","url":null,"abstract":"OBJECTIVE: We investigated the correlation between computed tomography (CT) scores, laboratory findings, and clinical symptoms in patients with coronavirus disease 2019 (COVID-19). MATERIALS AND METHODS: Clinical, laboratory, and thorax CT findings on the admission of 121 patients with COVID-19 were retrospectively evaluated. CT scores based on lobe involvement and CT patterns (i.e., ground-glass abnormalities, consolidation, and crazy-paving patterns) were estimated, and the relationship between CT score and symptomatic (e.g. fever, cough) versus asymptomatic (e.g., inflammation, coagulation, liver and kidney function) clinical laboratory findings were statistically analyzed. RESULTS: Sixty-eight of 121 patients (56%) were symptomatic; 53 (44%) were asymptomatic. The CT scores of symptomatic patients, especially those with coughing and dyspnea, were statistically higher (2 [0–9] vs. 0 [0–1]; P < 0.001). Erythrocyte sedimentation rate, C-reactive protein, ferritin, D-dimer, fibrinogen, aspartate aminotransferase, lactate dehydrogenase, glucose, prothrombin time and alanine amino transferase values were correlated with CT scores (ρ = 0.638, P < 0.001, ρ = 0.512, P < 0.001; ρ = 0.325, P = 0.001; ρ = 0.452, P < 0.001; ρ = 0.525, P < 0.001; ρ = 0.379, P < 0.001; ρ = 0.445, P < 0.001; ρ = 0.332, P < 0.001, ρ = 0.296, P = 0.003; ρ = 0.222, P = 0.015, respectively). Albumin values were negatively correlated with CT scores (ρ = −0.398, P < 0.001). CONCLUSION: CT scores may help clinicians evaluate the severity of COVID-19 pneumonia and thus help in managing the disease.","PeriodicalId":101055,"journal":{"name":"Radiology of Infectious Diseases","volume":"87 1","pages":"9 - 16"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81197752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Liver injury is found in some patients with coronavirus disease-2019 (COVID-19). Both the clinical treatment efficacy and the patient's prognosis are affected by the severity of liver injury. In addition, in some cases, liver injury may occur in the absence of respiratory symptoms. To date, liver injury diagnosed based on laboratory findings and abdominal computed tomography (CT) has been reported in COVID-19 patients. The aim of this review was to summarize the mechanism of liver injury caused by COVID-19 and describe the CT features of COVID-19-induced liver damage.
{"title":"Mechanism and computed tomography features of liver injury caused by coronavirus disease 2019: Current status","authors":"Fu-lin Lu, Jing Ou, Rui Li, Bang-guo Tan, Xiaoming Zhang, Tianwu Chen, Hongjun Li","doi":"10.4103/RID.RID_5_21","DOIUrl":"https://doi.org/10.4103/RID.RID_5_21","url":null,"abstract":"Liver injury is found in some patients with coronavirus disease-2019 (COVID-19). Both the clinical treatment efficacy and the patient's prognosis are affected by the severity of liver injury. In addition, in some cases, liver injury may occur in the absence of respiratory symptoms. To date, liver injury diagnosed based on laboratory findings and abdominal computed tomography (CT) has been reported in COVID-19 patients. The aim of this review was to summarize the mechanism of liver injury caused by COVID-19 and describe the CT features of COVID-19-induced liver damage.","PeriodicalId":101055,"journal":{"name":"Radiology of Infectious Diseases","volume":"20 1","pages":"42 - 44"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85165283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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