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Progress of artificial intelligence in imaging for the diagnosis of drug-resistant pulmonary tuberculosis 人工智能在耐药肺结核影像诊断中的研究进展
Pub Date : 2022-07-01 DOI: 10.4103/rid.rid_39_22
Chuanjun Xu, Qiuzhen Xu, Fengli Jiang, Yu Wang
Recent technical advances have led to the application of artificial intelligence in many areas of medical science. This approach was applied early on to medical imaging, which involves a large amount of data for diagnosis. The application of artificial intelligence and imaging diagnostics for disease screening, diagnosis, and prognosis prediction is an area of active research. Early diagnosis and effective management of drug-resistant pulmonary tuberculosis (TB) can effectively control the spread of Mycobacterium TB, reduce hospitalization, and improve prognosis. We review the progress of artificial intelligence in assisting imaging-based diagnosis of this disease, and we offer useful perspectives on future research in this area.
最近的技术进步导致人工智能在医学科学的许多领域的应用。这种方法早期应用于医学成像,这涉及到大量的诊断数据。人工智能和影像诊断在疾病筛查、诊断和预后预测中的应用是一个活跃的研究领域。耐药肺结核(TB)的早期诊断和有效管理可以有效控制结核分枝杆菌的传播,减少住院治疗,改善预后。我们回顾了人工智能在辅助基于图像的疾病诊断方面的进展,并对该领域的未来研究提出了有益的观点。
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引用次数: 0
Research progress of artificial intelligence-based imaging diagnosis of infectious diseases 基于人工智能的传染病影像诊断研究进展
Pub Date : 2022-07-01 DOI: 10.4103/rid.rid_30_22
Lin Guo, Li-Jun Xia, F. Lure, Hongjun Li
With the rapid development and progress of theory and technology, artificial intelligence (AI) has overcome many early technical limitations. Remarkable advances have recently been made in the application of AI to various areas of health care, and improvements in the performance of computer-aided diagnostics, such as accuracy, specificity, and processing speed, have been achieved, especially in the classification and identification of lesions. We review the various applications and worldwide progress of AI-based imaging diagnosis of infectious diseases.
随着理论和技术的快速发展和进步,人工智能(AI)已经克服了许多早期的技术限制。最近,人工智能在卫生保健各个领域的应用取得了显著进展,计算机辅助诊断的性能,如准确性、特异性和处理速度,特别是在病变的分类和识别方面取得了进步。本文综述了基于人工智能的传染病影像诊断的各种应用及国内外进展。
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引用次数: 0
Death probability analysis in the old aged population and smokers in India owing to COVID-19 COVID-19导致印度老年人口和吸烟者死亡概率分析
Pub Date : 2022-07-01 DOI: 10.4103/rid.rid_22_22
P. Jamdade, Shrinivas G. Jamdade
OBJECTIVE: Research has shown that older people and smokers have a higher death probability from coronavirus disease 2019 (COVID-19). Thus, we investigated the effect of COVID-19 on death probability for individuals aged 65–70 years and smokers in India. MATERIALS AND METHODS: We did so using a differential learning (feed-backward) model. In the present study, we examined World Health Organization (WHO) declared COVID-19 data of India. We divided the patients into two groups accordingly: the population aged 65–70 years and female or male smokers. RESULTS: We observed that in the early stages of infection (up to 5 days), there was higher death probability in the older population; among smokers, it occurred in the middle period after infection (5–8 days). We estimated that the death probability among smokers was 1.905 times that of the older population. CONCLUSION: As Government of India, taking various initiatives to curb the spread of COVID-19, but these are not enough, so we suggest measures that should help to reduce COVID-19 infection in India.
目的:研究表明,老年人和吸烟者死于2019冠状病毒病(COVID-19)的概率更高。因此,我们调查了COVID-19对印度65-70岁人群和吸烟者死亡概率的影响。材料和方法:我们使用了差分学习(反馈)模型。在本研究中,我们检查了世界卫生组织(WHO)宣布的印度COVID-19数据。我们将患者分为两组:65-70岁人群和女性或男性吸烟者。结果:我们观察到,在感染早期(最多5天),老年人群的死亡概率较高;吸烟者多发生在感染后中期(5-8天)。我们估计吸烟者的死亡概率是老年人的1.905倍。结论:作为印度政府,采取了各种措施来遏制COVID-19的传播,但这些措施还不够,因此我们提出了有助于减少印度COVID-19感染的措施。
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引用次数: 0
Computed tomography findings and clinical evidence of improvement in coronavirus disease 2019 infection after convalescent plasma therapy in a critically ill patient 1例危重患者恢复期血浆治疗后2019冠状病毒感染改善的计算机断层扫描结果和临床证据
Pub Date : 2022-07-01 DOI: 10.4103/rid.rid_32_22
Bangguo Tan, Jing Ou, Rui Li, Fu-lin Lu, Xiaoming Zhang, Tianwu Chen, Hongjun Li
The spread of severe acute respiratory syndrome coronavirus 2 worldwide has created a major threat to human life and safety. Antiviral drugs and antibiotics have poor therapeutic effects, and there is no specific treatment for this virus. Chest computed tomography (CT) plays an important role in the diagnosis and management of coronavirus disease 2019 (COVID-19). We report a patient who was critically ill with COVID-19 and recovered after receiving transfusions of convalescent plasma. To evaluate the efficacy of convalescent plasma in the treatment of COVID-19, we compared chest CT findings, clinical manifestations, and laboratory findings before and after treatment with convalescent plasma. After the transfusion of convalescent plasma, clinical manifestations and indicators of inflammation improved, accompanied by an increase in the partial pressure of oxygen and oxygen saturation. Chest CT showed some resolution of the lung lesions, and multiple viral nucleic acid tests were negative. Therefore, the patient's condition was improved after the transfusion of convalescent plasma, suggesting that it may be an effective treatment for patients who are critically ill with COVID-19.
严重急性呼吸综合征冠状病毒在全球范围内的传播对人类生命和安全构成了重大威胁。抗病毒药物和抗生素的治疗效果较差,对这种病毒没有特异性的治疗方法。胸部计算机断层扫描(CT)在2019冠状病毒病(COVID-19)的诊断和治疗中发挥着重要作用。我们报告一例COVID-19危重患者在接受恢复期血浆输血后康复。为评价恢复期血浆治疗新冠肺炎的疗效,比较恢复期血浆治疗前后胸部CT表现、临床表现及实验室检查结果。恢复期血浆输注后,临床表现及炎症指标改善,伴氧分压、血氧饱和度升高。胸部CT显示肺部病变消退,多项病毒核酸检测呈阴性。因此,恢复期血浆输血后患者病情得到改善,提示其可能是COVID-19危重患者的有效治疗方法。
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引用次数: 0
Advocacy to promote archiving of organ imaging data in Indian tertiary care centers 倡导在印度三级保健中心促进器官成像数据存档
Pub Date : 2022-07-01 DOI: 10.4103/rid.rid_26_22
J. Prakash, G. Chauhan, P. Bhattacharya, K. Saran
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引用次数: 0
Imaging characteristics of brain abscess in children with congenital heart disease 先天性心脏病患儿脑脓肿的影像学特征
Pub Date : 2022-04-01 DOI: 10.4103/rid.rid_14_22
Ke Liu, M. Zhu, Sudan Dong
BACKGROUND: Brain abscess is a rare disease in childhood requiring prompt medical and/or surgical treatment. The objective was to discuss the head computed tomography and magnetic resonance imaging characteristics of children with brain abscess in congenital heart disease (CHD) group compared with the group without CHD, further comprehend the imaging findings, and assess the severity of brain abscess in children with CHD. MATERIALS AND METHODS: The radiological features of brain abscess in children hospitalized in Shanghai Children's Medical Center between September 2014 and September 2021 were retrospectively reviewed. RESULTS: Forty-four children (14 females, 30 males), with a median age of 8.6 years (range 2–15 years), were enrolled in this study. CHD was found in 22 cases. Twenty-one of these 22 patients were with cyanotic CHD. The remaining 22 cases were without CHD. Among the 22 patients with CHD, superficial abscesses of 2–5 cm in diameter are the main imaging findings, which was the same as in children without CHD. In our study, brain abscesses of CHD are usually single, while other brain abscesses are usually multiple in children without CHD. There was statistically significant difference in the number of abscesses between the group with CHD and the group without CHD (χ2 = 6.3, P = 0.04). Compared with no CHD children, the nearest distance from the ventricular wall to the margin of brain abscess in children with CHD is often <7 mm. CONCLUSIONS: Brain abscesses in children with CHD have some special imaging characteristics. Superficial abscesses of 2–5 cm in diameter are the main imaging findings. Brain abscesses of CHD are usually single, while other brain abscesses are usually multiple in children without CHD. Compared with no CHD children, the nearest distance from the ventricular wall to the margin of brain abscess in children with CHD is shorter.
背景:脑脓肿是一种罕见的儿童疾病,需要及时的药物和/或手术治疗。目的是探讨先天性心脏病(CHD)患儿脑脓肿与非CHD患儿的头部ct和磁共振成像特点,进一步了解影像学表现,评估CHD患儿脑脓肿的严重程度。材料与方法:回顾性分析2014年9月至2021年9月上海儿童医疗中心住院患儿脑脓肿的影像学表现。结果:44名儿童(14名女性,30名男性)被纳入本研究,中位年龄8.6岁(范围2-15岁)。冠心病22例。22例患者中有21例为紫绀型冠心病。其余22例无冠心病。22例冠心病患者影像学表现以直径2-5 cm的浅表脓肿为主要表现,与非冠心病患儿相同。在我们的研究中,冠心病的脑脓肿通常是单发的,而在非冠心病的儿童中,其他脑脓肿通常是多发的。冠心病组与非冠心病组脓肿数比较,差异有统计学意义(χ2 = 6.3, P = 0.04)。与无冠心病患儿相比,冠心病患儿脑室壁至脑脓肿边缘最近距离常<7 mm。结论:CHD患儿脑脓肿具有一些特殊的影像学特征。主要影像学表现为直径2-5厘米的浅表脓肿。冠心病脑脓肿多为单发,非冠心病患儿多为多发脑脓肿。与未患冠心病的患儿相比,冠心病患儿从脑室壁到脑脓肿边缘的最近距离更短。
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引用次数: 0
Computed tomography-aided diagnosis of COVID-19 计算机断层扫描辅助诊断COVID-19
Pub Date : 2022-04-01 DOI: 10.4103/rid.rid_23_22
Xiao Chen, Qiuyuan Yang, Haijun He, Caiqiong Wang, Z. Peng, Yingchun Liu, Peiqi Wang, Jialei Wu, Bin Yang
Coronavirus disease (COVID-19) is highly infectious, has spread worldwide, and has a relatively high mortality rate. Early diagnosis and timely isolation are essential to control the spread of COVID-19. Computed tomography (CT) is considered to be an effective tool for the rapid diagnosis of COVID-19 and plays a key role in diagnosis, clinical course monitoring, and the evaluation of treatment outcomes. Artificial intelligence (AI) has emerged as a useful technology for early diagnosis, lesion quantification, and prognosis evaluation in patients with COVID-19. In this review, we discuss the role of CT in the diagnosis of COVID-19, typical CT manifestations of COVID-19 throughout the disease course, differential diagnoses, and the application of AI as a diagnostic and therapeutic tool in this patient population.
冠状病毒病(COVID-19)具有高度传染性,已在全球传播,死亡率相对较高。早期诊断和及时隔离对控制COVID-19的传播至关重要。计算机断层扫描(CT)被认为是快速诊断新冠肺炎的有效工具,在诊断、临床病程监测和治疗效果评估方面发挥着关键作用。人工智能(AI)已成为COVID-19患者早期诊断、病变量化和预后评估的有用技术。本文就CT在新冠肺炎诊断中的作用、新冠肺炎在整个病程中的典型CT表现、鉴别诊断以及人工智能作为诊断和治疗工具在该患者群体中的应用进行综述。
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引用次数: 0
Magnetic resonance imaging-based radiomics analysis for the assessment of hepatic alveolar echinococcosis biological activity: A preliminary study 基于磁共振成像的放射组学分析评估肝肺泡包虫病的生物活性:初步研究
Pub Date : 2022-04-01 DOI: 10.4103/rid.rid_21_22
Z. Miao, Ren Bo, Yuwei Xia, Wenya Liu
OBJECTIVE: The objective of this study was to develop and evaluate predictive models based on a combination of T2-weighted images (T2WI) and different machine learning algorithms, and to explore the value of hepatic alveolar echinococcosis (HAE) activity assessment by magnetic resonance imaging (MRI) radiomics. MATERIALS AND METHODS: This retrospective study included 136 patients diagnosed with HAE at the First Affiliated Hospital of Xinjiang Medical University between 2012 and 2020. All subjects underwent MRI and positron emission tomography–computed tomography (PET-CT) before surgery. Taking the PET-CT examination results as the reference standard, patients were divided into active (90 cases) and inactive groups (46 cases). The volume of interest of the lesion was manually delineated on T2WI, and quantitative radiomics features were extracted. Synthetic Minority Oversampling Technology was used to balance the number of patients in the categories. To control for redundancy, the least absolute shrinkage and selection operator was used for feature screening after normalization, and ten optimal features were obtained based on correlation coefficient screening. Three machine learning classifiers were trained using five-fold cross-validation and their performance was compared to establish an optimal HAE activity assessment model. The performance of the classifier was evaluated by area under the receiver operating characteristics curve (AUC), sensitivity, specificity, and accuracy (ACC). The ten optimal features selected from each fold were combined using three machine learning algorithms: logistic regression, multilayer perceptron (MLP), and support vector machine, to establish an HAE activity prediction model. RESULTS: The three machine learning classifiers all showed good prediction performance with a mean AUC on the test set of more than 0.80, and the MLP showing the best performance (AUC = 0.830 ± 0.053, ACC = 0.817, sensitivity = 0.822, and specificity = 0.811). CONCLUSION: HAE activity can be accurately evaluated by a radiomics method using a combination of quantitative T2WI features and machine learning.
目的:本研究的目的是建立和评估基于t2加权图像(T2WI)和不同机器学习算法的预测模型,并探讨磁共振成像(MRI)放射组学对肝肺泡包虫病(HAE)活动性评估的价值。材料与方法:本回顾性研究纳入2012年至2020年在新疆医科大学第一附属医院诊断为HAE的136例患者。所有受试者在手术前接受MRI和正电子发射断层扫描(PET-CT)。以PET-CT检查结果为参考标准,将患者分为活动组(90例)和非活动组(46例)。在T2WI上手动划定病灶的感兴趣体积,并提取定量放射组学特征。使用合成少数过采样技术来平衡类别中的患者数量。为控制冗余,归一化后采用最小绝对收缩和选择算子进行特征筛选,基于相关系数筛选得到10个最优特征。三种机器学习分类器使用五重交叉验证进行训练,并比较其性能,以建立最佳HAE活动评估模型。通过受试者工作特征曲线下面积(AUC)、灵敏度、特异性和准确性(ACC)对分类器的性能进行评价。利用三种机器学习算法:逻辑回归、多层感知器(MLP)和支持向量机,将从每个折叠中选出的10个最优特征组合在一起,建立HAE活动预测模型。结果:3种机器学习分类器均表现出较好的预测性能,在测试集上的平均AUC均大于0.80,其中MLP表现最好(AUC = 0.830±0.053,ACC = 0.817,灵敏度= 0.822,特异性= 0.811)。结论:利用定量T2WI特征和机器学习相结合的放射组学方法可以准确评估HAE的活动性。
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引用次数: 0
Exophytic cystic gastrointestinal stromal tumor mimics hepatic abscess or tumor 外生性囊性胃肠道间质瘤与肝脓肿或肿瘤相似
Pub Date : 2022-04-01 DOI: 10.4103/rid.rid_8_21
Guisen Lin, RenHua Wu
A middle-aged patient presented with epigastric pain, elevated white blood cell count, and mild anemia. Computed tomography (CT) revealed an exophytic gastric mass that mimicked a hepatic abscess or tumor, with intraperitoneal hemorrhage. The mass had heterogeneous texture, interstitial bleeding, and cystic change that showed delayed mild enhancement on multiphase CT. This was consistent with gastrointestinal stromal tumor that was confirmed by pathological and immunohistochemical analysis.
一个中年病人表现为胃脘痛,白细胞计数升高,轻度贫血。计算机断层扫描(CT)显示一个外生性胃肿块,模仿肝脓肿或肿瘤,并伴有腹腔出血。肿块质地不均,间质性出血和囊性改变,在多期CT上表现为延迟的轻度增强。经病理及免疫组化分析证实为胃肠道间质瘤。
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引用次数: 0
Role of chest radiography in COVID-19: A retrospective observational study in a tertiary care hospital in Southern India 胸部x线摄影在COVID-19中的作用:印度南部一家三级医院的回顾性观察研究
Pub Date : 2022-04-01 DOI: 10.4103/rid.rid_11_22
Badusha Mohammad, Namratha Nandimandalam, Sampath Yerramsetti, Sravani Penumetcha, Bharghav Bathula
OBJECTIVES: The objective of this study is to evaluate the clinical profile of coronavirus disease-2019 (COVID-19) patients admitted to our hospital and to correlate their chest radiographic patterns with disease severity. MATERIALS AND METHODS: We retrospectively reviewed 500 patients with COVID-19 confirmed by reverse transcription-polymerase chain reaction who had abnormal baseline chest X-rays (CXRs) at the time of hospital admission. CXRs were characterized based on the site and nature of the lesions. Disease severity was determined using the Radiographic Assessment of Lung Edema (RALE) score. RESULTS: Significant associations were found between (1) the lesion site and patient outcome (P < 0.00001): patients with diffuse and basal infiltrates had high intensive care unit (ICU) admission rates (55.5% and 40%) and mortality rates (30.5% and 20%); (2) the nature of the lesion and patient outcome: patients with ground-glass opacities and consolidation had high mortality (20% and 18%, respectively); and (3) the RALE score and patient outcome: patients with a RALE score >15 had higher ICU admission and mortality rates. CONCLUSIONS: The CXR distribution patterns helped to triage patients and predict outcomes.
目的:本研究的目的是评估入院的冠状病毒病-2019 (COVID-19)患者的临床特征,并将其胸片表现与疾病严重程度联系起来。材料和方法:我们回顾性分析了500例经逆转录聚合酶链反应确诊的COVID-19患者,这些患者在入院时有异常的基线胸片(cxr)。根据病变的部位和性质来确定cxr的特征。采用肺水肿影像学评估(RALE)评分确定疾病严重程度。结果:(1)病变部位与患者预后之间存在显著相关性(P < 0.00001):弥漫性和基底性浸润患者的ICU住院率(55.5%和40%)和死亡率(30.5%和20%)较高;(2)病变性质和患者预后:毛玻璃混浊和实变患者死亡率高(分别为20%和18%);(3) RALE评分与患者预后:RALE评分>15的患者ICU入院率和死亡率较高。结论:CXR分布模式有助于患者分诊和预测预后。
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引用次数: 0
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Radiology of Infectious Diseases
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