Pub Date : 2017-04-25DOI: 10.3969/CJCNN.V17I4.1572
Jia-Ling Wu
{"title":"Rehabilitation treatment in acute stage of stroke","authors":"Jia-Ling Wu","doi":"10.3969/CJCNN.V17I4.1572","DOIUrl":"https://doi.org/10.3969/CJCNN.V17I4.1572","url":null,"abstract":"","PeriodicalId":10113,"journal":{"name":"中国现代神经疾病杂志","volume":"17 1","pages":"241-244"},"PeriodicalIF":0.0,"publicationDate":"2017-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43190686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-04-25DOI: 10.3969/CJCNN.V17I4.1575
Hongbin Wang, Hua Long, Hua Yuan, Qiang Duan, Nan Hui, Hong Wang, Li Mao, Xiang Mou
Objective To investigate the effect of low-frequency repetitive transcranial magnetic stimulation (rTMS) combined with task-oriented training on the recovery of upper limb motor function of stroke patients. Methods A total of 42 patients with hemiplegia after stroke were randomly divided into control group (N = 20) and treatment group (N = 22). Control group received routine rehabilitation training and task-oriented training, and treatment group received low-frequency (1 Hz) rTMS over the contralesional cortex addition to routine rehabilitation and task-oriented training. Fugl-Meyer Assessment Scale for Upper Extremity (FMA-UE) and Wolf Motor Function Test (WMFT) were used to evaluate upper limb motor function of all patients before treatment, after 4-week treatment and 3 months after treatment. The latency and central motor conduction time (CMCT) of motor-evoked potential (MEP) in the contralesional cortex were recorded and analyzed. Results Compared with control group, FMA-UE score ( P = 0.006) and WMFT score ( P = 0.024) were significantly increased in treatment group. There was significant difference in FMA-AUE score ( P = 0.000) and WMFT score ( P = 0.000) at different time points. Compared with before treatment, FMA-UE score ( P = 0.000, for all) and WMFT score ( P = 0.000, for all) of patients in both groups were all significantly increased after 4-week treatment and 3 months after treatment. Besides, FMA-UE score ( P = 0.000, for all) and WMFT score ( P = 0.000, for all) 3 months after treatment were higher than those after 4-week treatment. There was no statistically significant difference between 2 groups on the latency ( P = 0.979) and CMCT ( P = 0.807) of MEP before and after treatment, and so was the difference on the latency ( P = 0.085) and CMCT ( P = 0.507) of MEP in the contralesional cortex at different time points (before treatment, after 4-week treatment and 3 months after treatment). Conclusions Low-frequency rTMS over the contralesional cortex combined with task-oriented training could greatly promote upper limb motor function of patients after stroke, and should be recommended to clinical application. DOI: 10.3969/j.issn.1672-6731.2017.04.004
{"title":"Effect of low-frequency repetitive transcranial magnetic stimulation combining task-oriented training on upper limb motor function recovery after stroke","authors":"Hongbin Wang, Hua Long, Hua Yuan, Qiang Duan, Nan Hui, Hong Wang, Li Mao, Xiang Mou","doi":"10.3969/CJCNN.V17I4.1575","DOIUrl":"https://doi.org/10.3969/CJCNN.V17I4.1575","url":null,"abstract":"Objective To investigate the effect of low-frequency repetitive transcranial magnetic stimulation (rTMS) combined with task-oriented training on the recovery of upper limb motor function of stroke patients. Methods A total of 42 patients with hemiplegia after stroke were randomly divided into control group (N = 20) and treatment group (N = 22). Control group received routine rehabilitation training and task-oriented training, and treatment group received low-frequency (1 Hz) rTMS over the contralesional cortex addition to routine rehabilitation and task-oriented training. Fugl-Meyer Assessment Scale for Upper Extremity (FMA-UE) and Wolf Motor Function Test (WMFT) were used to evaluate upper limb motor function of all patients before treatment, after 4-week treatment and 3 months after treatment. The latency and central motor conduction time (CMCT) of motor-evoked potential (MEP) in the contralesional cortex were recorded and analyzed. Results Compared with control group, FMA-UE score ( P = 0.006) and WMFT score ( P = 0.024) were significantly increased in treatment group. There was significant difference in FMA-AUE score ( P = 0.000) and WMFT score ( P = 0.000) at different time points. Compared with before treatment, FMA-UE score ( P = 0.000, for all) and WMFT score ( P = 0.000, for all) of patients in both groups were all significantly increased after 4-week treatment and 3 months after treatment. Besides, FMA-UE score ( P = 0.000, for all) and WMFT score ( P = 0.000, for all) 3 months after treatment were higher than those after 4-week treatment. There was no statistically significant difference between 2 groups on the latency ( P = 0.979) and CMCT ( P = 0.807) of MEP before and after treatment, and so was the difference on the latency ( P = 0.085) and CMCT ( P = 0.507) of MEP in the contralesional cortex at different time points (before treatment, after 4-week treatment and 3 months after treatment). Conclusions Low-frequency rTMS over the contralesional cortex combined with task-oriented training could greatly promote upper limb motor function of patients after stroke, and should be recommended to clinical application. DOI: 10.3969/j.issn.1672-6731.2017.04.004","PeriodicalId":10113,"journal":{"name":"中国现代神经疾病杂志","volume":"17 1","pages":"254-260"},"PeriodicalIF":0.0,"publicationDate":"2017-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45314602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-04-25DOI: 10.3969/CJCNN.V17I4.1574
Chunli Gao, Jia-Ling Wu
Post-stroke depression (PSD) is a serious complication affecting the survival and functional recovery of stroke patients. The prevalence rate of PSD is about 30% . PSD happens mostly within one year after stroke, and especially within 3 months after stroke. The main risk factors of PSD were disability, past history of depression, stroke severity, cognitive dysfunction and anxiety symptoms. The treatment principles of PSD include drug treatment, psychological therapy, rehabilitation therapy, physical therapy and others. Especially, rehabilitation therapy can significantly reduce the incidence of PSD and improve the prognosis. Further study on the mechanism of PSD and optimization of PSD rehabilitation therapy can improve PSD prognosis. DOI: 10.3969/j.issn.1672-6731.2017.04.003
{"title":"Advances in clinical research of post-stroke depression","authors":"Chunli Gao, Jia-Ling Wu","doi":"10.3969/CJCNN.V17I4.1574","DOIUrl":"https://doi.org/10.3969/CJCNN.V17I4.1574","url":null,"abstract":"Post-stroke depression (PSD) is a serious complication affecting the survival and functional recovery of stroke patients. The prevalence rate of PSD is about 30% . PSD happens mostly within one year after stroke, and especially within 3 months after stroke. The main risk factors of PSD were disability, past history of depression, stroke severity, cognitive dysfunction and anxiety symptoms. The treatment principles of PSD include drug treatment, psychological therapy, rehabilitation therapy, physical therapy and others. Especially, rehabilitation therapy can significantly reduce the incidence of PSD and improve the prognosis. Further study on the mechanism of PSD and optimization of PSD rehabilitation therapy can improve PSD prognosis. DOI: 10.3969/j.issn.1672-6731.2017.04.003","PeriodicalId":10113,"journal":{"name":"中国现代神经疾病杂志","volume":"12 S1","pages":"249-253"},"PeriodicalIF":0.0,"publicationDate":"2017-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41266009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-04-01DOI: 10.3969/CJCNN.V17I4.1576
Bao-jin Li, Cheng Li, Jing Li, Q. Gao
Background Trunk is the core part of human body, and plays an important role in maintaining the body balance. Studies show that trunk control training can improve the balance function and mobility ability, and promote motor function and activities of daily living (ADL) of stroke patients. This study aims to investigate the effect of early trunk control training on the recovery of balance function of acute stroke patients. Methods A total of 120 patients with acute ischemic stroke (duration ≤ 14 d) were randomly divided into 2 groups: control group [N = 60, 39 males and 21 females; age 23-85 years, mean age (63.43 ± 13.61) years; duration 1-13 d, median duration 4.12 (2.30, 6.09) d] and observation group [N = 60, 40 males and 20 females; age 20-84 years, average age (62.55 ± 13.77) years; duration 1-12 d, median duration 4.19 (2.48, 6.30) d]. Control group was given routine drug treatment plus rehabilitation education and guidance, and observation group was given routine drug treatment, rehabilitation education and guidance plus trunk control training. Fugl-Meyer Assessment Scale-Balance (FMA-Balance) and Modified Rivermead Mobility Index (MRMI) were used to evaluate the balance function of patients in both groups before training and after 2-week training. Results All patients finished the rehabilitation training programme without adverse reactions. Compared with before training, the scores of FMA-Balance ( P =0.000) and MRMI ( P = 0.000) were significantly increased after 2-week training in both groups. Compared to control group, the scores of FMA-Balance ( P = 0.002) and MRMI ( P = 0.002) were significantly increased after 2-week training in observation group. Conclusions Early trunk control training can significantly improve the balance function and motor ability of patients with acute stroke. DOI: 10.3969/j.issn.1672-6731.2017.04.005
{"title":"Effect of early trunk control training on balance function of patients with acute stroke","authors":"Bao-jin Li, Cheng Li, Jing Li, Q. Gao","doi":"10.3969/CJCNN.V17I4.1576","DOIUrl":"https://doi.org/10.3969/CJCNN.V17I4.1576","url":null,"abstract":"Background Trunk is the core part of human body, and plays an important role in maintaining the body balance. Studies show that trunk control training can improve the balance function and mobility ability, and promote motor function and activities of daily living (ADL) of stroke patients. This study aims to investigate the effect of early trunk control training on the recovery of balance function of acute stroke patients. Methods A total of 120 patients with acute ischemic stroke (duration ≤ 14 d) were randomly divided into 2 groups: control group [N = 60, 39 males and 21 females; age 23-85 years, mean age (63.43 ± 13.61) years; duration 1-13 d, median duration 4.12 (2.30, 6.09) d] and observation group [N = 60, 40 males and 20 females; age 20-84 years, average age (62.55 ± 13.77) years; duration 1-12 d, median duration 4.19 (2.48, 6.30) d]. Control group was given routine drug treatment plus rehabilitation education and guidance, and observation group was given routine drug treatment, rehabilitation education and guidance plus trunk control training. Fugl-Meyer Assessment Scale-Balance (FMA-Balance) and Modified Rivermead Mobility Index (MRMI) were used to evaluate the balance function of patients in both groups before training and after 2-week training. Results All patients finished the rehabilitation training programme without adverse reactions. Compared with before training, the scores of FMA-Balance ( P =0.000) and MRMI ( P = 0.000) were significantly increased after 2-week training in both groups. Compared to control group, the scores of FMA-Balance ( P = 0.002) and MRMI ( P = 0.002) were significantly increased after 2-week training in observation group. Conclusions Early trunk control training can significantly improve the balance function and motor ability of patients with acute stroke. DOI: 10.3969/j.issn.1672-6731.2017.04.005","PeriodicalId":10113,"journal":{"name":"中国现代神经疾病杂志","volume":"17 1","pages":"261-265"},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43211133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-04-01DOI: 10.3969/CJCNN.V17I4.1573
Bing Li, Fang Li
Virtual reality (VR) rehabilitation technology is a kind of integrated technology which simulates the real world via computer. It has three characteristics: immersion, interaction and imagination. It is widely used in the field of stroke rehabilitation. This review briefly describes the application of virtual reality rehabilitation technology in upper limb dysfunction after stroke. DOI: 10.3969/j.issn.1672-6731.2017.04.002
{"title":"Application progress of virtual reality rehabilitation technology in upper limb dysfunction after stroke","authors":"Bing Li, Fang Li","doi":"10.3969/CJCNN.V17I4.1573","DOIUrl":"https://doi.org/10.3969/CJCNN.V17I4.1573","url":null,"abstract":"Virtual reality (VR) rehabilitation technology is a kind of integrated technology which simulates the real world via computer. It has three characteristics: immersion, interaction and imagination. It is widely used in the field of stroke rehabilitation. This review briefly describes the application of virtual reality rehabilitation technology in upper limb dysfunction after stroke. DOI: 10.3969/j.issn.1672-6731.2017.04.002","PeriodicalId":10113,"journal":{"name":"中国现代神经疾病杂志","volume":"17 1","pages":"245-248"},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49570292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-03-25DOI: 10.3969/CJCNN.V17I3.1559
Lin Meng, Dan Huang, Hong-hong Liu, Yun Qu
Survivors of stroke commonly experience a different range of dysfunction, and recovery can be slow and incomplete, which lead to a serious and long-term impact on patients themselves and their families. Although the treatment of stroke patients relies mainly on rehabilitation intervention, but the rehabilitation needs of discharged patients are not fully met due to lots of restrictions, such as the lack of professional rehabilitation services, the difficulty and inconvenience in transportation from home to hospital, therefore their prognosis of rehabilitation are affected. At present a number of new rehabilitation technologies, including telerehabilitation (TR), virtual reality (VR), robotics, electronic textiles (E-textiles), etc., are coming into being and may solve these problems. This article tries to discuss the research progress of these new rehabilitation technologies, and provide a new perspective for the rehabilitation intervention of stroke patients. DOI: 10.3969/j.issn.1672-6731.2017.03.003
{"title":"Research progress of new technologies in stroke rehabilitation","authors":"Lin Meng, Dan Huang, Hong-hong Liu, Yun Qu","doi":"10.3969/CJCNN.V17I3.1559","DOIUrl":"https://doi.org/10.3969/CJCNN.V17I3.1559","url":null,"abstract":"Survivors of stroke commonly experience a different range of dysfunction, and recovery can be slow and incomplete, which lead to a serious and long-term impact on patients themselves and their families. Although the treatment of stroke patients relies mainly on rehabilitation intervention, but the rehabilitation needs of discharged patients are not fully met due to lots of restrictions, such as the lack of professional rehabilitation services, the difficulty and inconvenience in transportation from home to hospital, therefore their prognosis of rehabilitation are affected. At present a number of new rehabilitation technologies, including telerehabilitation (TR), virtual reality (VR), robotics, electronic textiles (E-textiles), etc., are coming into being and may solve these problems. This article tries to discuss the research progress of these new rehabilitation technologies, and provide a new perspective for the rehabilitation intervention of stroke patients. DOI: 10.3969/j.issn.1672-6731.2017.03.003","PeriodicalId":10113,"journal":{"name":"中国现代神经疾病杂志","volume":"17 1","pages":"171-175"},"PeriodicalIF":0.0,"publicationDate":"2017-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44676594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-03-25DOI: 10.3969/CJCNN.V17I3.1570
Bai-yuan Yang, Wei Zhong, Shuai Li, Xinglong Yang
{"title":"Aortic dissection with weakness of lower limb as initial symptom: one case report","authors":"Bai-yuan Yang, Wei Zhong, Shuai Li, Xinglong Yang","doi":"10.3969/CJCNN.V17I3.1570","DOIUrl":"https://doi.org/10.3969/CJCNN.V17I3.1570","url":null,"abstract":"","PeriodicalId":10113,"journal":{"name":"中国现代神经疾病杂志","volume":"17 1","pages":"232-234"},"PeriodicalIF":0.0,"publicationDate":"2017-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42898678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-03-25DOI: 10.3969/CJCNN.V17I3.1560
Da Xu, Deng Chen, Lina Zhu, G. Tan, Haijiao Wang, Ling Liu
Objective To evaluate the efficacy of antiplatelet agents in secondary prevention of patients with lacunar infarct (LACI). Methods Retrieve relevant randomized controlled trials (RCTs) that reported antiplatelet therapy in patients with LACI from online databases (January 1, 1980-November 20, 2016) in PubMed, EMBASE/SCOPUS and Cochrane Online Library with key words: stroke, lacunar infarction, platelet aggregation inhibitors, antiplatelet, randomized controlled trial. Quality of studies was evaluated by using Jadad Scale and Cochrane Handbook for Systematic Reviews of Interventions. All data were pooled by RevMan 5.3 software for Meta-analysis. A network Meta-analysis was done by R software Gemtc and JAGS software. Results A total of 4068 articles were enrolled and 12 high - quality RCTs (Jadad ≥ 4 scores) with 24 969 eligible participants were finally included after excluding duplicates and those not meeting the inclusion criteria. Meta-analysis showed single antiplatelet therapy was more effective than placebo in reducing ischemic stroke recurrence rate ( RR = 0.480, 95%CI: 0.300-0.780; P = 0.003) and any stroke recurrence rate ( RR = 0.780, 95%CI: 0.630-0.970; P = 0.030). The efficacy of single antiplatelet therapy was not significantly different from that of dual antiplatelet therapy (ischemic stroke recurrence rate: RR = 0.900, 95%CI: 0.760-1.050, P = 0.170; any stroke recurrence rate: RR = 0.910, 95%CI: 0.820-1.010, P = 0.070). Network Meta-analysis (four interventions including aspirin, placebo, cilostazol and ticlopidine) showed that cilostazol was associated with a significant reduction in recurrence of any stroke compared with aspirin ( OR = 0.341, 95% CrI: 0.011-0.673) and placebo ( OR = 0.615, 95% CrI: 0.191-1.042). Conclusions Single antiplatelet therapy could significantly reduce the recurrence of any stroke, especially ischemic stroke in patients with LACI. There is no evidence showing that dual antiplatelet therapy is probably better than single therapy. Cilostazol is better than aspirin in reducing any stroke recurrence in the treatment of LACI. DOI: 10.3969/j.issn.1672-6731.2017.03.004
{"title":"Efficacy of antiplatelet therapy for treating lacunar infarct: Meta-analysis","authors":"Da Xu, Deng Chen, Lina Zhu, G. Tan, Haijiao Wang, Ling Liu","doi":"10.3969/CJCNN.V17I3.1560","DOIUrl":"https://doi.org/10.3969/CJCNN.V17I3.1560","url":null,"abstract":"Objective To evaluate the efficacy of antiplatelet agents in secondary prevention of patients with lacunar infarct (LACI). Methods Retrieve relevant randomized controlled trials (RCTs) that reported antiplatelet therapy in patients with LACI from online databases (January 1, 1980-November 20, 2016) in PubMed, EMBASE/SCOPUS and Cochrane Online Library with key words: stroke, lacunar infarction, platelet aggregation inhibitors, antiplatelet, randomized controlled trial. Quality of studies was evaluated by using Jadad Scale and Cochrane Handbook for Systematic Reviews of Interventions. All data were pooled by RevMan 5.3 software for Meta-analysis. A network Meta-analysis was done by R software Gemtc and JAGS software. Results A total of 4068 articles were enrolled and 12 high - quality RCTs (Jadad ≥ 4 scores) with 24 969 eligible participants were finally included after excluding duplicates and those not meeting the inclusion criteria. Meta-analysis showed single antiplatelet therapy was more effective than placebo in reducing ischemic stroke recurrence rate ( RR = 0.480, 95%CI: 0.300-0.780; P = 0.003) and any stroke recurrence rate ( RR = 0.780, 95%CI: 0.630-0.970; P = 0.030). The efficacy of single antiplatelet therapy was not significantly different from that of dual antiplatelet therapy (ischemic stroke recurrence rate: RR = 0.900, 95%CI: 0.760-1.050, P = 0.170; any stroke recurrence rate: RR = 0.910, 95%CI: 0.820-1.010, P = 0.070). Network Meta-analysis (four interventions including aspirin, placebo, cilostazol and ticlopidine) showed that cilostazol was associated with a significant reduction in recurrence of any stroke compared with aspirin ( OR = 0.341, 95% CrI: 0.011-0.673) and placebo ( OR = 0.615, 95% CrI: 0.191-1.042). Conclusions Single antiplatelet therapy could significantly reduce the recurrence of any stroke, especially ischemic stroke in patients with LACI. There is no evidence showing that dual antiplatelet therapy is probably better than single therapy. Cilostazol is better than aspirin in reducing any stroke recurrence in the treatment of LACI. DOI: 10.3969/j.issn.1672-6731.2017.03.004","PeriodicalId":10113,"journal":{"name":"中国现代神经疾病杂志","volume":"17 1","pages":"176-184"},"PeriodicalIF":0.0,"publicationDate":"2017-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43503099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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