Pub Date : 2016-04-01DOI: 10.4103/2468-5585.185198
B. Sevinç, O. Karahan, S. Ay, N. Aksoy, A. Okuş
Aim: The study aims to evaluate the relation between red cell distribution width (RDW) and papillary thyroid carcinoma. RDW is a part of routine complete blood count which shows the heterogeneity of the circulating red cells. Studies showed that RDW increases in inflammatory disorders. Methods: The patients′ data from 100 cases with total thyroidectomy were retrospectively evaluated. A total of 50 cases with thyroid papillary carcinoma and 50 cases with benign thyroid nodule were included into the evaluation. Results: The mean RDW value was 14.5 ± 1.7 in papillary carcinoma group and 13.4 ± 0.8 in benign thyroid nodule group. Other hematological parameters of the groups were similar. According to the receiver operating characteristic (ROC) curve, the optimal RDW value for thyroid papillary carcinoma was found to be 12.95% with a sensitivity of 88.00% and specificity of 70.00% (the area under an ROC curve: 0.718, P < 0.001). Conclusion: There is no study in literature evaluating the relation between RDW value and papillary thyroid carcinoma. According to the recent study, an increase in RDW value can be a helping parameter in differentiating papillary carcinoma from benign thyroid nodule.
{"title":"Red cell distribution width as a marker of thyroid papillary carcinoma","authors":"B. Sevinç, O. Karahan, S. Ay, N. Aksoy, A. Okuş","doi":"10.4103/2468-5585.185198","DOIUrl":"https://doi.org/10.4103/2468-5585.185198","url":null,"abstract":"Aim: The study aims to evaluate the relation between red cell distribution width (RDW) and papillary thyroid carcinoma. RDW is a part of routine complete blood count which shows the heterogeneity of the circulating red cells. Studies showed that RDW increases in inflammatory disorders. Methods: The patients′ data from 100 cases with total thyroidectomy were retrospectively evaluated. A total of 50 cases with thyroid papillary carcinoma and 50 cases with benign thyroid nodule were included into the evaluation. Results: The mean RDW value was 14.5 ± 1.7 in papillary carcinoma group and 13.4 ± 0.8 in benign thyroid nodule group. Other hematological parameters of the groups were similar. According to the receiver operating characteristic (ROC) curve, the optimal RDW value for thyroid papillary carcinoma was found to be 12.95% with a sensitivity of 88.00% and specificity of 70.00% (the area under an ROC curve: 0.718, P < 0.001). Conclusion: There is no study in literature evaluating the relation between RDW value and papillary thyroid carcinoma. According to the recent study, an increase in RDW value can be a helping parameter in differentiating papillary carcinoma from benign thyroid nodule.","PeriodicalId":102077,"journal":{"name":"Translational Surgery","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131840747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-04-01DOI: 10.4103/2468-5585.185200
S. Ocak, H. Alakus, M. Duymus, M. Kaya, K. Karadayi, Neşe Yeldir, H. Ozer, E. Colak
Myeloid sarcoma (MS) is an extramedullary tumor of the myeloid cells and usually develops in lymphoid organs, bones, skin, adipose tissue, and the central nervous system. Gastrointestinal or isolated mesenteric involvement is an extremely rare without bone marrow (BM) involvement. Only a few cases had reported before. In this paper, we report a case of a 37-year-old male who presented with small bowel intussusception due to mesenteric MS. Abdominal computed tomography findings revealed intussusception of the small bowel in the left lower quadrant of the abdomen and mesenteric masses. The patient underwent operation, and masses were excised with segmental small bowel and segmental colon resection because the masses were adjacent to the bowel wall. Histopathology and immunohistochemistry showed MS in mesentery. Patient received 2 cycles of cytosine arabinoside combined with idarubicin chemotherapy in the postoperative period and was doing well at 6 months of follow-up. MS in mesentery presenting as intussusception of small bowel without BM involvement is very rare and it should be considered in the differential diagnosis of intestinal obstruction.
{"title":"Nonleukemic myeloid sarcoma presenting as intussusception of small bowel in a male patient: An unusual presentation","authors":"S. Ocak, H. Alakus, M. Duymus, M. Kaya, K. Karadayi, Neşe Yeldir, H. Ozer, E. Colak","doi":"10.4103/2468-5585.185200","DOIUrl":"https://doi.org/10.4103/2468-5585.185200","url":null,"abstract":"Myeloid sarcoma (MS) is an extramedullary tumor of the myeloid cells and usually develops in lymphoid organs, bones, skin, adipose tissue, and the central nervous system. Gastrointestinal or isolated mesenteric involvement is an extremely rare without bone marrow (BM) involvement. Only a few cases had reported before. In this paper, we report a case of a 37-year-old male who presented with small bowel intussusception due to mesenteric MS. Abdominal computed tomography findings revealed intussusception of the small bowel in the left lower quadrant of the abdomen and mesenteric masses. The patient underwent operation, and masses were excised with segmental small bowel and segmental colon resection because the masses were adjacent to the bowel wall. Histopathology and immunohistochemistry showed MS in mesentery. Patient received 2 cycles of cytosine arabinoside combined with idarubicin chemotherapy in the postoperative period and was doing well at 6 months of follow-up. MS in mesentery presenting as intussusception of small bowel without BM involvement is very rare and it should be considered in the differential diagnosis of intestinal obstruction.","PeriodicalId":102077,"journal":{"name":"Translational Surgery","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116684831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-01-01DOI: 10.4103/2468-5585.179565
Z. Demetrashvili, D. Loladze, Ketevan Vibliani, Tamar Metreveli
Most ingested foreign bodies (FBs) pass through the gastrointestinal tract without any problems, although their passage depends on shape and size. When a FB is relatively large, endoscopic removal may be utilized in most cases (the success rate was 95%), but sometimes surgery is required. We present a case report of a 27-year-old woman with epilepsy who had swallowed a fork in a suicide attempt. A plain abdominal radiograph confirmed a FB (fork) in the stomach with no visible pneumoperitoneum. On objective examination, the abdomen was soft and nontender with no peritoneal irritation. After a failed attempt at endoscopic removal, the laparoscopic intervention was undertaken. The operation was performed under general anesthesia utilizing open laparoscopy (Hasson's technique). As a result, the fork was successfully removed without further complications. After 72 h, she was discharged from the hospital without any complications. The patient was followed up after 4 weeks and made a full recovery.
{"title":"Successful laparoscopic removal of ingested fork","authors":"Z. Demetrashvili, D. Loladze, Ketevan Vibliani, Tamar Metreveli","doi":"10.4103/2468-5585.179565","DOIUrl":"https://doi.org/10.4103/2468-5585.179565","url":null,"abstract":"Most ingested foreign bodies (FBs) pass through the gastrointestinal tract without any problems, although their passage depends on shape and size. When a FB is relatively large, endoscopic removal may be utilized in most cases (the success rate was 95%), but sometimes surgery is required. We present a case report of a 27-year-old woman with epilepsy who had swallowed a fork in a suicide attempt. A plain abdominal radiograph confirmed a FB (fork) in the stomach with no visible pneumoperitoneum. On objective examination, the abdomen was soft and nontender with no peritoneal irritation. After a failed attempt at endoscopic removal, the laparoscopic intervention was undertaken. The operation was performed under general anesthesia utilizing open laparoscopy (Hasson's technique). As a result, the fork was successfully removed without further complications. After 72 h, she was discharged from the hospital without any complications. The patient was followed up after 4 weeks and made a full recovery.","PeriodicalId":102077,"journal":{"name":"Translational Surgery","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133558878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-01-01DOI: 10.4103/2468-5585.179564
John Yoon, S. Burjonrappa
Aim: Anti-reflux surgery is offered to those who fail medical management for gastroesophageal reflux disease (GERD) in the pediatric population. A handful of studies show that those with neurologic impairment have benefited from these procedures; however, there are a few studies that document the indications and outcomes for infants < 6 months of age. Methods: A retrospective analysis of children < 6 months of age who underwent a Nissen fundoplication (NF) at St. Joseph's Regional Medical Center from December 2006 to June 2013 was performed. The following factors, such as surgical indications, comorbidities, hospital course data, weight gain, length of stay, and complications, were analyzed. Results: A total of 23 patients with the average age of 95.8 days were studied in this analysis. Presurgery, the average weight of these patients was 9.88 percentile (interquartile range: 5.85). A total of 65.2% patients were considered having failure to thrive (FTT) as they were under the 10th percentile and 78% patients had anatomic or genetic abnormalities. Nearly 47.8% patients underwent upper gastrointestinal studies that were positive for reflux. All patients had a concomitant gastrostomy tube (G-tube) placed during the NF. Diet was advanced on the average postoperative day of 2, and the patients tolerated the highest diet by the postoperative day of 6. Most patients saw a decrease in medications after the procedure. Moreover, 7 patients had complications related to the G-tube, with the main complication reported as leakage around the tube. There were two mortalities, both unrelated to the operation. Conclusion: Infants undergoing NF under the age of 6 months typically present with multiple comorbidities. NF in this population will not only lead to weight gain but also decrease in overall need for GERD-related medications. Early recognition of the failure of nasojejunal feeds will facilitate NF before significant FTT is present.
{"title":"Nissen fundoplication in severely ill infants: A STROBE compliant study","authors":"John Yoon, S. Burjonrappa","doi":"10.4103/2468-5585.179564","DOIUrl":"https://doi.org/10.4103/2468-5585.179564","url":null,"abstract":"Aim: Anti-reflux surgery is offered to those who fail medical management for gastroesophageal reflux disease (GERD) in the pediatric population. A handful of studies show that those with neurologic impairment have benefited from these procedures; however, there are a few studies that document the indications and outcomes for infants < 6 months of age. Methods: A retrospective analysis of children < 6 months of age who underwent a Nissen fundoplication (NF) at St. Joseph's Regional Medical Center from December 2006 to June 2013 was performed. The following factors, such as surgical indications, comorbidities, hospital course data, weight gain, length of stay, and complications, were analyzed. Results: A total of 23 patients with the average age of 95.8 days were studied in this analysis. Presurgery, the average weight of these patients was 9.88 percentile (interquartile range: 5.85). A total of 65.2% patients were considered having failure to thrive (FTT) as they were under the 10th percentile and 78% patients had anatomic or genetic abnormalities. Nearly 47.8% patients underwent upper gastrointestinal studies that were positive for reflux. All patients had a concomitant gastrostomy tube (G-tube) placed during the NF. Diet was advanced on the average postoperative day of 2, and the patients tolerated the highest diet by the postoperative day of 6. Most patients saw a decrease in medications after the procedure. Moreover, 7 patients had complications related to the G-tube, with the main complication reported as leakage around the tube. There were two mortalities, both unrelated to the operation. Conclusion: Infants undergoing NF under the age of 6 months typically present with multiple comorbidities. NF in this population will not only lead to weight gain but also decrease in overall need for GERD-related medications. Early recognition of the failure of nasojejunal feeds will facilitate NF before significant FTT is present.","PeriodicalId":102077,"journal":{"name":"Translational Surgery","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114661912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-01-01DOI: 10.4103/2468-5585.179562
G. Currò, G. Navarra
During the last 2 decades, technological advances as high-definition cameras along with three-dimensional vision systems, vessel sealing devices, and articulating instruments have added safety, efficacy, and precision to laparoscopic procedures. The need to develop even more minimally invasive surgical techniques has led laparoscopic surgeons to try to reduce the number of skin incisions or to avoid them altogether, and change the way to approach peritoneal cavity. Natural orifice transluminal endoscopic surgery and single incision laparoscopic surgery represent the surgeon's attempt to reduce invasiveness and body image trauma perception and improved esthetics in comparison with conventional laparoscopic surgery. All these innovations have been successfully applied to laparoscopic cholecystectomy. However, it is still debated when and how to use them instead of conventional procedures.
{"title":"New frontiers in mini-invasive biliary surgery: Single incision laparoscopic surgery, natural orifice transluminal endoscopic surgery, and robotics","authors":"G. Currò, G. Navarra","doi":"10.4103/2468-5585.179562","DOIUrl":"https://doi.org/10.4103/2468-5585.179562","url":null,"abstract":"During the last 2 decades, technological advances as high-definition cameras along with three-dimensional vision systems, vessel sealing devices, and articulating instruments have added safety, efficacy, and precision to laparoscopic procedures. The need to develop even more minimally invasive surgical techniques has led laparoscopic surgeons to try to reduce the number of skin incisions or to avoid them altogether, and change the way to approach peritoneal cavity. Natural orifice transluminal endoscopic surgery and single incision laparoscopic surgery represent the surgeon's attempt to reduce invasiveness and body image trauma perception and improved esthetics in comparison with conventional laparoscopic surgery. All these innovations have been successfully applied to laparoscopic cholecystectomy. However, it is still debated when and how to use them instead of conventional procedures.","PeriodicalId":102077,"journal":{"name":"Translational Surgery","volume":"157 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127546322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-01-01DOI: 10.4103/2468-5585.179566
Yan Liang, Jun Guo, Zhe Zhang, Yang-Jie Li, Yuan Zhang
Aim: To explore the effect of intensive statin therapy (different doses) on percutaneous coronary intervention (PCI) outcomes in elderly patients with coronary heart disease (CHD). Methods: In this Institutional Ethics Committee-approved study, 105 elderly patients (> 80-year-old) with CHD admitted into the First Affiliated Hospital of Jinan University from June 2012 to June 2014 were randomly divided into three groups and received 20 mg/day, 40 mg/day, or 60 mg/day atorvastatin, respectively, before PCI surgery. Postsurgical (1 month after surgery) changes in major adverse cardiovascular events (MACEs), cardiac markers, vaspin, and adiponectin levels were compared among the groups. Results: Among the study groups, the incidence of MACE and PCI-related myocardial infarction rate was the lowest in 60 mg group (2.9%) reaching significance (P < 0.05). Although postsurgical cardiac marker levels increased significantly (P < 0.05), the values were found inversely correlated to statin dose (P < 0.05). Postsurgical vaspin, adiponectin, and alanine aminotransferase levels significantly increased in 60 mg group (P < 0.05). There was no considerable difference between presurgical and postsurgical serum creatinine and blood urea nitrogen levels in any group (P > 0.05). No study subjects showed statin-related myopathy. Conclusion: The application of 60 mg/d intensive statin therapy in short term could improve outcomes of PCI in patients with elderly CHD, maintain stable levels of cardiac markers, Vaspin and adiponectin, with exact effect and good safety.
{"title":"Effect of intensive statin therapy on coronary intervention outcomes, cardiac markers, vaspin, and adiponectin levels in elderly patients with coronary heart disease","authors":"Yan Liang, Jun Guo, Zhe Zhang, Yang-Jie Li, Yuan Zhang","doi":"10.4103/2468-5585.179566","DOIUrl":"https://doi.org/10.4103/2468-5585.179566","url":null,"abstract":"Aim: To explore the effect of intensive statin therapy (different doses) on percutaneous coronary intervention (PCI) outcomes in elderly patients with coronary heart disease (CHD). Methods: In this Institutional Ethics Committee-approved study, 105 elderly patients (> 80-year-old) with CHD admitted into the First Affiliated Hospital of Jinan University from June 2012 to June 2014 were randomly divided into three groups and received 20 mg/day, 40 mg/day, or 60 mg/day atorvastatin, respectively, before PCI surgery. Postsurgical (1 month after surgery) changes in major adverse cardiovascular events (MACEs), cardiac markers, vaspin, and adiponectin levels were compared among the groups. Results: Among the study groups, the incidence of MACE and PCI-related myocardial infarction rate was the lowest in 60 mg group (2.9%) reaching significance (P < 0.05). Although postsurgical cardiac marker levels increased significantly (P < 0.05), the values were found inversely correlated to statin dose (P < 0.05). Postsurgical vaspin, adiponectin, and alanine aminotransferase levels significantly increased in 60 mg group (P < 0.05). There was no considerable difference between presurgical and postsurgical serum creatinine and blood urea nitrogen levels in any group (P > 0.05). No study subjects showed statin-related myopathy. Conclusion: The application of 60 mg/d intensive statin therapy in short term could improve outcomes of PCI in patients with elderly CHD, maintain stable levels of cardiac markers, Vaspin and adiponectin, with exact effect and good safety.","PeriodicalId":102077,"journal":{"name":"Translational Surgery","volume":"167 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132937416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-01-01DOI: 10.4103/2468-5585.179563
Ö. Karahan, B. Sevinç, G. Şimşek, Recep Demirgül
Aim: Pilonidal disease is an inflammatory disorder, mainly affecting young adults. Platelet-rich plasma (PRP) is shown to have a positive impact on the wound healing process. Herein, the study aims to define the application of PRP and report early results. Methods: The study data were collected prospectively. PRP was prepared from the patients' own blood samples, transformed into gel form, and applied to the sinus tract under local anesthesia. Furthermore, the healing rate and recurrence rate of the disease were evaluated. Results: There were 50 cases included in the study, with 48 cases were cured at the end of the 1st month. At this stage, with a median follow-up of 15 months, there have been no documented recurrences. Conclusion: Minimally invasive treatment of pilonidal disease with PRP application has promising results. Treatment of pilonidal disease by PRP can be applied in outpatient clinic and provides total cure in a short time. The method is simple, painless, with no hospital stay required, less wound care, shorter time to return daily activity, and the cost is effective. However, long-term outcomes are unknown, and additional follow-up is required.
{"title":"Minimally invasive treatment of pilonidal sinus disease using platelet-rich plasma","authors":"Ö. Karahan, B. Sevinç, G. Şimşek, Recep Demirgül","doi":"10.4103/2468-5585.179563","DOIUrl":"https://doi.org/10.4103/2468-5585.179563","url":null,"abstract":"Aim: Pilonidal disease is an inflammatory disorder, mainly affecting young adults. Platelet-rich plasma (PRP) is shown to have a positive impact on the wound healing process. Herein, the study aims to define the application of PRP and report early results. Methods: The study data were collected prospectively. PRP was prepared from the patients' own blood samples, transformed into gel form, and applied to the sinus tract under local anesthesia. Furthermore, the healing rate and recurrence rate of the disease were evaluated. Results: There were 50 cases included in the study, with 48 cases were cured at the end of the 1st month. At this stage, with a median follow-up of 15 months, there have been no documented recurrences. Conclusion: Minimally invasive treatment of pilonidal disease with PRP application has promising results. Treatment of pilonidal disease by PRP can be applied in outpatient clinic and provides total cure in a short time. The method is simple, painless, with no hospital stay required, less wound care, shorter time to return daily activity, and the cost is effective. However, long-term outcomes are unknown, and additional follow-up is required.","PeriodicalId":102077,"journal":{"name":"Translational Surgery","volume":"81 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132622015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-01-01DOI: 10.4103/2468-5585.179561
Z. Rifatbegović, A. Mestric, Z. Mehmedović
Cholecystostomy is considered to be a treatment option when conservative treatment of acute cholecystitis failed in elderly and critically ill patients. The aim of this paper is to present a cholecystostomy in the treatment of obstructive jaundice before the definitive operation for the underlying cause of jaundice. The patient in poor general condition with the obstructive jaundice was diagnosed to have a pancreatic head tumor. He had undergone the laparoscopic cholecystostomy. After improvement of the general condition and lower total bilirubin level, the patient had undergone to definitive procedure. It is shown that laparoscopic cholecystostomy can be a successful way for adequate bile drainage in a patient with poor general condition before the definitive treatment of obstructive jaundice.
{"title":"Laparoscopic cholecystostomy in treatment of obstructive jaundice","authors":"Z. Rifatbegović, A. Mestric, Z. Mehmedović","doi":"10.4103/2468-5585.179561","DOIUrl":"https://doi.org/10.4103/2468-5585.179561","url":null,"abstract":"Cholecystostomy is considered to be a treatment option when conservative treatment of acute cholecystitis failed in elderly and critically ill patients. The aim of this paper is to present a cholecystostomy in the treatment of obstructive jaundice before the definitive operation for the underlying cause of jaundice. The patient in poor general condition with the obstructive jaundice was diagnosed to have a pancreatic head tumor. He had undergone the laparoscopic cholecystostomy. After improvement of the general condition and lower total bilirubin level, the patient had undergone to definitive procedure. It is shown that laparoscopic cholecystostomy can be a successful way for adequate bile drainage in a patient with poor general condition before the definitive treatment of obstructive jaundice.","PeriodicalId":102077,"journal":{"name":"Translational Surgery","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122982290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}