Objective: To analyze the impact and clinical application value of implementing VIP nursing mode in obstetric wards on postpartum delivery. Method: 250 postpartum women who were hospitalized and delivered at Yiwu Central Hospital from January 2017 to December 2018 were selected. They were divided into a control group of 125 cases and an observation group of 125 cases based on different nursing methods. The control group received routine obstetric care, while the observation group received VIP obstetric care. The nursing effects of the two groups of patients were analyzed. The first stage of labor time (321.13 ± 28.91) minutes, second stage of labor time (23.25 ± 8.66) minutes, third stage of labor time (6.12 ± 1.02) minutes, and total stage of labor time (259.18 ± 36.03) minutes in the observation group were all shorter than those in the control group, and the differences were statistically significant (t=11.308, 13.874, 12.194, 15.879, all P<0.05). The postpartum bleeding volume of the observation group was (171.43 ± 19.06) mL, the pain score was (1.78 ± 1.01) points, the hospital stay was (4.02 ± 1.12) days, the nursing satisfaction score was (95.13 ± 3.76) points, and the cesarean section rate was 12.80%. There were statistically significant differences compared to the control group (t=14.438, 12.398, 14.392, 15.093) χ 2=4.013, all P<0.05). In the observation group, there were 2 cases of puerperal infection, 1 case of cervical laceration, 4 cases of postpartum urinary retention, and 0 case of neonatal asphyxia; There were 11 cases of puerperal infection, 13 cases of cervical laceration, 16 cases of postpartum urinary retention, and 6 cases of neonatal asphyxia in the control group. The difference between the two groups was statistically significant（ χ 2=3.478, 3.917, 4.018, 4.881, all P<0.05). Conclusion: Implementing VIP nursing mode in obstetric wards can shorten the delivery process and hospitalization time, reduce postpartum hemorrhage and perinatal complications, and reduce the cesarean section rate.
{"title":"Effect of implementation of VIP in obstetric ward on the quality of nursing management","authors":"L. Chen","doi":"10.3760/CMA.J.ISSN.1008-6706.2020.07.028","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1008-6706.2020.07.028","url":null,"abstract":"目的 \u0000分析产科病房开展贵宾式(VIP)护理模式对产妇分娩的影响和临床应用价值。 \u0000 \u0000 \u0000方法 \u0000选取义乌中心医院2017年1月至2018年12月住院分娩的产妇250例，根据护理方法不同分为对照组125例和观察组125例。对照组采取常规产科护理，观察组采取VIP产科护理模式，分析两组患者护理效果。 \u0000 \u0000 \u0000结果 \u0000观察组第一产程时间(321.13±28.91)min，第二产程时间(23.25±8.66)min，第三产程时间(6.12±1.02)min，总产程时间(259.18±36.03)min，均短于对照组，差异均有统计学意义(t＝11.308、13.874、12.194、15.879，均P<0.05)。观察组产后出血量(171.43±19.06)mL，疼痛评分(1.78±1.01)分，住院时间(4.02±1.12)d，护理满意度评分(95.13±3.76)分，剖宫产率12.80%，与对照组比较差异均有统计学意义(t＝14.438、12.398、14.392、15.093、χ2＝4.013，均P<0.05)。观察组发生产褥期感染2例，宫颈裂伤1例，产后尿潴留4例，新生儿窒息0例；对照组发生产褥期感染11例，宫颈裂伤13例，产后尿潴留16例，新生儿窒息6例，两组差异均有统计学意义(χ2＝3.478、3.917、4.018、4.881，均P<0.05)。 \u0000 \u0000 \u0000结论 \u0000产科病房开展VIP护理模式可以缩短产程和住院时间，减少产后出血量和围生期并发症，降低剖宫产率。","PeriodicalId":10226,"journal":{"name":"中国基层医药","volume":"27 1","pages":"885-887"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45981544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-04-01DOI: 10.3760/CMA.J.ISSN.1008-6706.2020.07.011
Jianxiang Yang, Jingbin Yan, Jian-hua Zheng
Objective To observe the clinical effect of two-dimensional speckle tracking technique in diagnosis and prognosis evaluation of heart failure with left ventricular ejection fraction preservation. Methods A total of 64 heart failure patients with reduced left ventricular ejection fraction (HFNEF) and 64 healthy volunteers in the Integrated Traditional Chinese and Western Medicine Hospital of Wenzhou were selected from July 2016 to July 2018.Conventional echocardiography and two-dimensional speckle tracking were performed in all subjects.The hemodynamic parameters and strain parameters of two-dimensional speckle tracking were recorded.The differences of conventional echocardiographic parameters and two-dimensional speckle tracking strain parameters in different subjects were analyzed. Results The E/A (0.79±0.24) and E/E' value (18.93±3.41) in HFNEF patients had statistically significant differences compared with healthy subjects [(1.28±0.35) and (6.84±1.37)] (t=9.507, 23.294; P=0.000, 0.000). There were no statistically significant differences in HR, LAD, LVD, LVSD, LVPWD, LVEF and LVFS between HFNEF patients [(71.37±5.93)times/min, (35.32±4.37)mm, (47.13±5.01)mm, (9.24±1.76)mm, (9.35±1.82)mm, (63.98±5.37)%, (35.49±4.46)%] and healthy subjects [(70.14±5.28)times/min, (37.64±4.69)mm, (49.26±5.54)mm, (9.39±1.82)mm, (9.48±1.90)mm, (66.35±5.41)%, (34.02±4.17)%] (t=0.384-1.628; P=0.102-0.564). In HFNEF patients, the anterior septum, anterior wall, posterior wall, inferior wall and posterior wall of apical segment of left ventricle, the inferior wall and posterior wall of papillary muscle and the posterior wall, inferior wall and posterior wall of basal segment, SRs and ROT of left ventricle were significantly lower than those of healthy subjects, while GLS (-13.52±4.18) and GCS (-10.43±3.85) of left ventricle in HFNEF patients were significantly higher than those of healthy subjects [(-19.89±4.61) and (-15.67±4.24)] (t=8.947~14.063; P=0.000-0.000<0.05). After treatment, the clinical symptoms of HFNEF patients improved significantly in the whole apical segment of left ventricle, inferior and posterior wall of papillary muscle segment, posterior lateral wall, inferior wall, posterior wall SRs and left ventricular GLS, GCS and ROT (t=7.258-13.193; P=0.000-0.000<0.05). Two-dimensional strain GLS and GC values in HFNEF patients were negatively correlated with E/A values and positively correlated with E/E' value (r=-0.817, -0.763; P=0.004, 0.012<0.05), while two-dimensional strain ROT results were positively correlated with E/A values and negatively correlated with E/E' values (r=-0.805, -0.759; P=0.006, 0.014<0.05). Conclusion Left ventricular systolic function damage has occurred in HFNEF patients.Two-dimensional speckle tracking technique is highly sensitive to the changes of myocardial systolic function for HFNEF patients.It has high clinical value in the diagnosis and prognosis evaluation of HFNEF.Relevant clinical workers should pay a
{"title":"Clinical significane of two-dimensional speckle tracking technique in the evaluation of diagnosis and prognosis of heart failure with left ventricular ejection fraction preservation","authors":"Jianxiang Yang, Jingbin Yan, Jian-hua Zheng","doi":"10.3760/CMA.J.ISSN.1008-6706.2020.07.011","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1008-6706.2020.07.011","url":null,"abstract":"Objective \u0000To observe the clinical effect of two-dimensional speckle tracking technique in diagnosis and prognosis evaluation of heart failure with left ventricular ejection fraction preservation. \u0000 \u0000 \u0000Methods \u0000A total of 64 heart failure patients with reduced left ventricular ejection fraction (HFNEF) and 64 healthy volunteers in the Integrated Traditional Chinese and Western Medicine Hospital of Wenzhou were selected from July 2016 to July 2018.Conventional echocardiography and two-dimensional speckle tracking were performed in all subjects.The hemodynamic parameters and strain parameters of two-dimensional speckle tracking were recorded.The differences of conventional echocardiographic parameters and two-dimensional speckle tracking strain parameters in different subjects were analyzed. \u0000 \u0000 \u0000Results \u0000The E/A (0.79±0.24) and E/E' value (18.93±3.41) in HFNEF patients had statistically significant differences compared with healthy subjects [(1.28±0.35) and (6.84±1.37)] (t=9.507, 23.294; P=0.000, 0.000). There were no statistically significant differences in HR, LAD, LVD, LVSD, LVPWD, LVEF and LVFS between HFNEF patients [(71.37±5.93)times/min, (35.32±4.37)mm, (47.13±5.01)mm, (9.24±1.76)mm, (9.35±1.82)mm, (63.98±5.37)%, (35.49±4.46)%] and healthy subjects [(70.14±5.28)times/min, (37.64±4.69)mm, (49.26±5.54)mm, (9.39±1.82)mm, (9.48±1.90)mm, (66.35±5.41)%, (34.02±4.17)%] (t=0.384-1.628; P=0.102-0.564). In HFNEF patients, the anterior septum, anterior wall, posterior wall, inferior wall and posterior wall of apical segment of left ventricle, the inferior wall and posterior wall of papillary muscle and the posterior wall, inferior wall and posterior wall of basal segment, SRs and ROT of left ventricle were significantly lower than those of healthy subjects, while GLS (-13.52±4.18) and GCS (-10.43±3.85) of left ventricle in HFNEF patients were significantly higher than those of healthy subjects [(-19.89±4.61) and (-15.67±4.24)] (t=8.947~14.063; P=0.000-0.000<0.05). After treatment, the clinical symptoms of HFNEF patients improved significantly in the whole apical segment of left ventricle, inferior and posterior wall of papillary muscle segment, posterior lateral wall, inferior wall, posterior wall SRs and left ventricular GLS, GCS and ROT (t=7.258-13.193; P=0.000-0.000<0.05). Two-dimensional strain GLS and GC values in HFNEF patients were negatively correlated with E/A values and positively correlated with E/E' value (r=-0.817, -0.763; P=0.004, 0.012<0.05), while two-dimensional strain ROT results were positively correlated with E/A values and negatively correlated with E/E' values (r=-0.805, -0.759; P=0.006, 0.014<0.05). \u0000 \u0000 \u0000Conclusion \u0000Left ventricular systolic function damage has occurred in HFNEF patients.Two-dimensional speckle tracking technique is highly sensitive to the changes of myocardial systolic function for HFNEF patients.It has high clinical value in the diagnosis and prognosis evaluation of HFNEF.Relevant clinical workers should pay a","PeriodicalId":10226,"journal":{"name":"中国基层医药","volume":"27 1","pages":"813-818"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45365267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective To investigate the expression and clinical significance of endostatin (ES) and angiostatin (AS) in pterygium. Methods From January 2016 to December 2018, 60 cases (60 eyes) of pterygium tissue and 60 cases (60 eyes) of normal human conjunctival tissue were selected from the eye surgery of Traditional Chinese Medicine Hospital of Yiwu.HE staining was used to observe the morphological changes of pterygium and normal conjunctival tissue.Western blot was used to measure ES and AS protein levels in the tissues of pterygium group and control group. Results HE staining showed that in the normal bulbar conjunctival tissue, the stromal layer was connective tissue and the epithelial layer was columnar epithelium; in the pterygium, the basal layer had a large number of new blood vessels, fibroblasts, collagen fibers, and inflammatory cells infiltrated around the blood vessels; the epithelium showed different degrees of hyperplasia.The protein levels of ES and AS in pterygium tissues[(0.35±0.12), (0.62±0.17)] were higher than those in the control group [(0.13±0.08), (0.16±0.09)](t=11.816, 18.524, P=0.000, 0.000). The protein levels of ES and AS in the pterygium tissues of the recurrent group [(0.63±0.15), (0.87±0.21)] were higher than those in the initial group [(0.22±0.11), (0.45±0.16)](t=17.073, 12.323, P=0.000, 0.000). There was positive correlation between ES and AS in pterygium (r=0.571, P=0.000). Conclusion The levels of ES and AS in pterygium tissue are increased, and ES and AS may be involved in the occurrence and recurrence of pterygium. Key words: Pterygium; Inhibins; Angiostatins; Endothelial cells; Recurrence
{"title":"Expression and clinical significance of endostatin and angiostatin in pterygium","authors":"Jinrong Zhao, Weiwei Chen, Zhongping Jin, Zheng Zhang","doi":"10.3760/CMA.J.ISSN.1008-6706.2020.07.006","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1008-6706.2020.07.006","url":null,"abstract":"Objective \u0000To investigate the expression and clinical significance of endostatin (ES) and angiostatin (AS) in pterygium. \u0000 \u0000 \u0000Methods \u0000From January 2016 to December 2018, 60 cases (60 eyes) of pterygium tissue and 60 cases (60 eyes) of normal human conjunctival tissue were selected from the eye surgery of Traditional Chinese Medicine Hospital of Yiwu.HE staining was used to observe the morphological changes of pterygium and normal conjunctival tissue.Western blot was used to measure ES and AS protein levels in the tissues of pterygium group and control group. \u0000 \u0000 \u0000Results \u0000HE staining showed that in the normal bulbar conjunctival tissue, the stromal layer was connective tissue and the epithelial layer was columnar epithelium; in the pterygium, the basal layer had a large number of new blood vessels, fibroblasts, collagen fibers, and inflammatory cells infiltrated around the blood vessels; the epithelium showed different degrees of hyperplasia.The protein levels of ES and AS in pterygium tissues[(0.35±0.12), (0.62±0.17)] were higher than those in the control group [(0.13±0.08), (0.16±0.09)](t=11.816, 18.524, P=0.000, 0.000). The protein levels of ES and AS in the pterygium tissues of the recurrent group [(0.63±0.15), (0.87±0.21)] were higher than those in the initial group [(0.22±0.11), (0.45±0.16)](t=17.073, 12.323, P=0.000, 0.000). There was positive correlation between ES and AS in pterygium (r=0.571, P=0.000). \u0000 \u0000 \u0000Conclusion \u0000The levels of ES and AS in pterygium tissue are increased, and ES and AS may be involved in the occurrence and recurrence of pterygium. \u0000 \u0000 \u0000Key words: \u0000Pterygium; Inhibins; Angiostatins; Endothelial cells; Recurrence","PeriodicalId":10226,"journal":{"name":"中国基层医药","volume":"27 1","pages":"791-794"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44135307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: To understand the basic characteristics, treatment compliance, and reasons for loss of methadone maintenance therapy (MMT) among the population in Pingdingshan City, and to provide a basis for improving outpatient treatment efficiency. Method: Statistical analysis was conducted on the information of opioid addicts who were first enrolled in the Drug Maintenance Treatment Center of the Center for Disease Control and Prevention in Pingdingshan City since December 2017. Descriptive analysis was conducted on their demographic characteristics, past drug use, and MMT treatment. Regression models were used to analyze the influencing factors of maintenance rates. A total of 141 opium or heroin addicts were enrolled in MMT for the first time. The male to female ratio is 3.86:1; Age (43.96 ± 8.05) years old; 82 cases were unmarried, divorced or widowed, accounting for 58.16%; 94 cases with education level of junior high school or below, accounting for 66.67%; The age of initial drug use is (25.06 ± 6.34) years old; The duration of drug use is (9.07 ± 6.48) years, with a minimum of 5 months and a maximum of 27 years; 134 cases (95.04%) used opioids alone; There were 26 cases of drug injection behavior, accounting for 18.44%. The average medication dose during the treatment period was (69.54 ± 25.07) mL. The MMT maintenance rate was 40.43% (57/141). The maintenance rate of MMT is higher among patients with high education level, close residence to the outpatient clinic, convenient transportation, long drug use time, and high daily medication dosage. Conclusion: MMT patients in Pingdingshan City are mainly male, unmarried, and those with a junior high school or lower education level, which is consistent with other regions. To increase the maintenance rate, additional service extension points should be added, and attention should be paid to the population with low education, short drug use time, and low medication dosage.
{"title":"Characteristics and treatment of methadone maintenance therapy in Pingdingshan city, Henan province","authors":"Xiaoling Duan, G. Ma","doi":"10.3760/CMA.J.ISSN.1008-6706.2020.07.024","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1008-6706.2020.07.024","url":null,"abstract":"目的 \u0000了解平顶山市参加美沙酮维持治疗(MMT)人群的基本特征、治疗依从性以及脱失原因，为提高门诊治疗效率提供依据。 \u0000 \u0000 \u0000方法 \u0000统计平顶山市疾病预防控制中心药物维持治疗中心2017年12月以来首次入组的阿片类物质成瘾者信息，对其人口学特征、既往毒品使用情况和MMT治疗情况进行描述性分析，并用回归模型分析维持率的影响因素。 \u0000 \u0000 \u0000结果 \u0000首次入组MMT的鸦片或海洛因成瘾者共141例。男女比例为3.86∶1；年龄(43.96±8.05)岁；未婚、离异或丧偶82例，占58.16%；初中及以下文化程度94例，占66.67%；初次吸毒年龄为(25.06±6.34)岁；吸毒时间(9.07±6.48)年，最短5个月，最长27年；单纯使用阿片类者134例，占95.04%；曾有毒品注射行为者26例，占18.44%。治疗期间平均服药剂量为(69.54±25.07)mL。MMT维持率为40.43%(57/141)。MMT维持率在文化程度高、居住地离门诊近、交通方便、吸毒时间长、日均服药剂量大的患者中较高。 \u0000 \u0000 \u0000结论 \u0000平顶山市MMT患者以男性、非在婚状态者、初中及以下文化程度者为主，与其他地区一致。提高维持率需增设服务延伸点，应关注低文化、吸毒时间短、服药剂量小的人群。","PeriodicalId":10226,"journal":{"name":"中国基层医药","volume":"27 1","pages":"872-875"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48954453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-04-01DOI: 10.3760/CMA.J.ISSN.1008-6706.2020.07.002
Honghong Su, Chen Gong, Jinhu Wang, Cao Ji-jun, Yong Li, Yuemei Zhang
Objective To understand the infection and distribution of syphilis in hospitalized patients, thus to provide reference for syphilis prevention and control. Methods TP-ELISA test was used to examine early syphilis antibody, and adopted the TPPA test to validation syphilis antibody, and TRUST was used to determine the titer of syphilis antibody in 80 478 hospitalized patients from January 2015 to November 2017, then the results were retrospectively analyzed. Results Among 80 478 inpatients, 1 326 cases were positive by TP-ELISA test(1 223 cases positive, 101 cases weak positive and 2 cases negative by TPPA confirmed). The positive rates of TP-ELISA in different years were 1.62%(445/27 394), 1.72%(490/28 412) and 1.58%(389/24 672), respectively, and the difference was not statistically significant(P>0.05). The positive rates of male and female patients were 2.02%(689/33 985) and 1.37%(635/46 479), and the difference was statistically significant(χ2=52.91, P=0.00). The positive rates of ≤18 years old, >18-59 years old, >59-79 years old and>79 years old were 0.32%(7/2 161), 1.44%(765/53 001), 2.31%(488/21 163) and 1.50%(62/4 153), respectively.The highest proportion of syphilis patients was in the group of >59-79 years old, and the differences were statistically significant compared with the other groups(χ2=37.08, 67.05, 10.80, all P<0.01). Among the TP-ELISA positive patients, 54.90%(728/1 326) had TRUST titer negative, 36.50%(484/1 326) had titer less than 1∶8, and the others had 8.44%(112/1 326). Conclusion The incidence of syphilis was higher in males than in females in 80 478 hospitalized patients.The highest positive rate was found in >59-79 years old group, and the number of elderly cases increased rapidly.Therefore, the effective interventions should be developed to control the transmission of syphilis according to the epidemiological features. Key words: Inpatients; Syphilis; Antibodies; Syphilis serodiagnosis; Enzyme-linked immunosorbent assay; Agglutination tests; False positive reactions; Laboratory techniques and procedures
{"title":"Detection and analysis of syphilis antibody in 80 478 cases of inpatients","authors":"Honghong Su, Chen Gong, Jinhu Wang, Cao Ji-jun, Yong Li, Yuemei Zhang","doi":"10.3760/CMA.J.ISSN.1008-6706.2020.07.002","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1008-6706.2020.07.002","url":null,"abstract":"Objective \u0000To understand the infection and distribution of syphilis in hospitalized patients, thus to provide reference for syphilis prevention and control. \u0000 \u0000 \u0000Methods \u0000TP-ELISA test was used to examine early syphilis antibody, and adopted the TPPA test to validation syphilis antibody, and TRUST was used to determine the titer of syphilis antibody in 80 478 hospitalized patients from January 2015 to November 2017, then the results were retrospectively analyzed. \u0000 \u0000 \u0000Results \u0000Among 80 478 inpatients, 1 326 cases were positive by TP-ELISA test(1 223 cases positive, 101 cases weak positive and 2 cases negative by TPPA confirmed). The positive rates of TP-ELISA in different years were 1.62%(445/27 394), 1.72%(490/28 412) and 1.58%(389/24 672), respectively, and the difference was not statistically significant(P>0.05). The positive rates of male and female patients were 2.02%(689/33 985) and 1.37%(635/46 479), and the difference was statistically significant(χ2=52.91, P=0.00). The positive rates of ≤18 years old, >18-59 years old, >59-79 years old and>79 years old were 0.32%(7/2 161), 1.44%(765/53 001), 2.31%(488/21 163) and 1.50%(62/4 153), respectively.The highest proportion of syphilis patients was in the group of >59-79 years old, and the differences were statistically significant compared with the other groups(χ2=37.08, 67.05, 10.80, all P<0.01). Among the TP-ELISA positive patients, 54.90%(728/1 326) had TRUST titer negative, 36.50%(484/1 326) had titer less than 1∶8, and the others had 8.44%(112/1 326). \u0000 \u0000 \u0000Conclusion \u0000The incidence of syphilis was higher in males than in females in 80 478 hospitalized patients.The highest positive rate was found in >59-79 years old group, and the number of elderly cases increased rapidly.Therefore, the effective interventions should be developed to control the transmission of syphilis according to the epidemiological features. \u0000 \u0000 \u0000Key words: \u0000Inpatients; Syphilis; Antibodies; Syphilis serodiagnosis; Enzyme-linked immunosorbent assay; Agglutination tests; False positive reactions; Laboratory techniques and procedures","PeriodicalId":10226,"journal":{"name":"中国基层医药","volume":"27 1","pages":"773-775"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49430342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-04-01DOI: 10.3760/CMA.J.ISSN.1008-6706.2020.07.018
Lin Shi, Yang Zhan, Xuetong Sun
Objective To compare the safety and efficacy of stent-assisted and non-stent-assisted coil embolization in the treatment of anterior communicating ruptured wide-necked aneurysms in acute phase. Methods The clinical data of 76 patients with anterior traffic rupture wide-necked aneurysm treated by interventional embolism from January 2014 to December 2018 were collected in the People's Hospital of Dezhou.According to whether or not stents were assisted during the operation, 76 cases were divided into stent group (41 cases) and non-stent group (35 cases). The stent group selected the Solitaire AB neurovascular remodoring device or the LVIS support for the corresponding size according to the diameter of the patients’ artery, and the non-stent group used a single catheter, a double catheter, or a balloon assist.The perioperative complications, mortality and clinical prognosis between the two groups were compared. Results There were no statistically significant differences in bleeding complications, symptomatic vasospasm, mortality and clinical prognosis between the two groups (all P>0.05). The incidence of ischemic complications in the stent group was 17.07%(7/41), which was significantly higher than that in the non-stent group[2.86%(1/35)](χ2=4.052, P<0.05). The overall complication rate of the stent group was 21.95%(9/41), which was significantly higher than 5.71%(2/35) of the non-stent group (χ2=4.021, P<0.05). Conclusion Both stent-assisted and non-stent-assisted coils can achieve good clinical results in the treatment of anterior communicating ruptured wide-necked aneurysms in acute phase.Stent-assisted embolism has a high incidence of ischemic complications and needs caution in clinical application. Key words: Intracranial aneurysm; Subarachnoid hemorrhage; Embolization, therapeutic; Tissue scaffolds; Postoperative complications; Prognosis
{"title":"Comparison of stent-assisted and non-stent-assisted coils in the treatment of ruptured wide-necked anterior communicating artery aneurysm in acute stage","authors":"Lin Shi, Yang Zhan, Xuetong Sun","doi":"10.3760/CMA.J.ISSN.1008-6706.2020.07.018","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1008-6706.2020.07.018","url":null,"abstract":"Objective \u0000To compare the safety and efficacy of stent-assisted and non-stent-assisted coil embolization in the treatment of anterior communicating ruptured wide-necked aneurysms in acute phase. \u0000 \u0000 \u0000Methods \u0000The clinical data of 76 patients with anterior traffic rupture wide-necked aneurysm treated by interventional embolism from January 2014 to December 2018 were collected in the People's Hospital of Dezhou.According to whether or not stents were assisted during the operation, 76 cases were divided into stent group (41 cases) and non-stent group (35 cases). The stent group selected the Solitaire AB neurovascular remodoring device or the LVIS support for the corresponding size according to the diameter of the patients’ artery, and the non-stent group used a single catheter, a double catheter, or a balloon assist.The perioperative complications, mortality and clinical prognosis between the two groups were compared. \u0000 \u0000 \u0000Results \u0000There were no statistically significant differences in bleeding complications, symptomatic vasospasm, mortality and clinical prognosis between the two groups (all P>0.05). The incidence of ischemic complications in the stent group was 17.07%(7/41), which was significantly higher than that in the non-stent group[2.86%(1/35)](χ2=4.052, P<0.05). The overall complication rate of the stent group was 21.95%(9/41), which was significantly higher than 5.71%(2/35) of the non-stent group (χ2=4.021, P<0.05). \u0000 \u0000 \u0000Conclusion \u0000Both stent-assisted and non-stent-assisted coils can achieve good clinical results in the treatment of anterior communicating ruptured wide-necked aneurysms in acute phase.Stent-assisted embolism has a high incidence of ischemic complications and needs caution in clinical application. \u0000 \u0000 \u0000Key words: \u0000Intracranial aneurysm; Subarachnoid hemorrhage; Embolization, therapeutic; Tissue scaffolds; Postoperative complications; Prognosis","PeriodicalId":10226,"journal":{"name":"中国基层医药","volume":"27 1","pages":"846-849"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46018440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-04-01DOI: 10.3760/CMA.J.ISSN.1008-6706.2020.07.022
Zhidi Li
Objective To investigate the efficacy and safety of new oral anticoagulants in the treatment of elderly patients with non-valvular atrial fibrillation. Methods From March 2016 to September 2018, 176 elderly patients with non-valvular atrial fibrillation admitted to Lyucheng Cardiovascular Hospital of Zhejiang Province were selected and divided into warfarin group(56 cases), dabiga group(64 cases) and rivaroxaban group(56 cases) according to the treatment conditions.All three groups were treated for 6 months.The incidence of embolism and bleeding events, the changes of blood sugar and liver, kidney function before and after treatment in three groups were compared. Results The incidence rates of thromboembolism in the warfarin group, dabiga group and rivaroxaban group were 7.14%(4/56), 1.56%(1/64), 3.57%(2/56), respectively, there was no statistically significant difference among the three groups(U=2.457, P>0.05). The incidences of bleeding in the warfarin group, dabiga group and rivaroxaban group were 16.07%(9/56), 3.13%(2/64), 1.79%(1/56), respectively, there was statistically significant difference among the three groups(U=11.090, P 0.05). Conclusion Compared with warfarin, the new oral anticoagulant dapigatron ester and rivaroxaban have similar effects in preventing stroke and thromboembolism in elderly patients with non-valvular atrial fibrillation, while the risk of bleeding events during the administration of dapigatron ester and rivaroxaban is lower, suggesting that the new oral anticoagulant is effective in the treatment of stroke and thromboembolism in elderly patients with non-valvular atrial fibrillation.The therapy has high efficacy and safety, which is worthy of clinical promotion. Key words: Atrial fibrillation; Anticoagulants; Warfarin; Dabicarbonate; Rivaroxaban; Safety; Aged
目的探讨新型口服抗凝剂治疗老年非瓣膜性心房颤动的疗效和安全性。方法选取2016年3月~ 2018年9月在浙江省柳城心血管医院住院的老年非瓣膜性心房颤动患者176例，根据治疗情况分为华法林组(56例)、达比加组(64例)和利伐沙班组(56例)。三组均治疗6个月。比较三组患者治疗前后栓塞、出血事件的发生率、血糖及肝肾功能的变化。结果华法林组、达比加组、利伐沙班组血栓栓塞发生率分别为7.14%(4/56)、1.56%(1/64)、3.57%(2/56)，三组间差异无统计学意义(U=2.457, P < 0.05)。华法林组、达比加组、利伐沙班组出血发生率分别为16.07%(9/56)、3.13%(2/64)、1.79%(1/56)，三组间差异有统计学意义(U=11.090, P 0.05)。结论与华法林相比，新型口服抗凝剂达吡加酮酯和利伐沙班对老年非瓣膜性房颤患者卒中和血栓栓塞的预防效果相似，而达吡加酮酯和利伐沙班用药期间发生出血事件的风险较低，提示新型口服抗凝剂治疗老年非瓣膜性房颤卒中和血栓栓塞是有效的。该疗法疗效高，安全性好，值得临床推广。关键词:心房颤动;抗凝血剂;华法令阻凝剂;Dabicarbonate;Rivaroxaban;安全;岁的
{"title":"Analysis of efficacy and safety of new oral anticoagulants in the treatment of elderly patients with non-valvular atrial fibrillation","authors":"Zhidi Li","doi":"10.3760/CMA.J.ISSN.1008-6706.2020.07.022","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1008-6706.2020.07.022","url":null,"abstract":"Objective \u0000To investigate the efficacy and safety of new oral anticoagulants in the treatment of elderly patients with non-valvular atrial fibrillation. \u0000 \u0000 \u0000Methods \u0000From March 2016 to September 2018, 176 elderly patients with non-valvular atrial fibrillation admitted to Lyucheng Cardiovascular Hospital of Zhejiang Province were selected and divided into warfarin group(56 cases), dabiga group(64 cases) and rivaroxaban group(56 cases) according to the treatment conditions.All three groups were treated for 6 months.The incidence of embolism and bleeding events, the changes of blood sugar and liver, kidney function before and after treatment in three groups were compared. \u0000 \u0000 \u0000Results \u0000The incidence rates of thromboembolism in the warfarin group, dabiga group and rivaroxaban group were 7.14%(4/56), 1.56%(1/64), 3.57%(2/56), respectively, there was no statistically significant difference among the three groups(U=2.457, P>0.05). The incidences of bleeding in the warfarin group, dabiga group and rivaroxaban group were 16.07%(9/56), 3.13%(2/64), 1.79%(1/56), respectively, there was statistically significant difference among the three groups(U=11.090, P 0.05). \u0000 \u0000 \u0000Conclusion \u0000Compared with warfarin, the new oral anticoagulant dapigatron ester and rivaroxaban have similar effects in preventing stroke and thromboembolism in elderly patients with non-valvular atrial fibrillation, while the risk of bleeding events during the administration of dapigatron ester and rivaroxaban is lower, suggesting that the new oral anticoagulant is effective in the treatment of stroke and thromboembolism in elderly patients with non-valvular atrial fibrillation.The therapy has high efficacy and safety, which is worthy of clinical promotion. \u0000 \u0000 \u0000Key words: \u0000Atrial fibrillation; Anticoagulants; Warfarin; Dabicarbonate; Rivaroxaban; Safety; Aged","PeriodicalId":10226,"journal":{"name":"中国基层医药","volume":"27 1","pages":"863-867"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44418620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-04-01DOI: 10.3760/CMA.J.ISSN.1008-6706.2020.07.005
Jie-Wei Wang
Objective To investigate the clinical value of transcranial Doppler ultrasound(TCD) combined with carotid ultrasound in the diagnosis of vertebral-basilar artery stenosis. Methods From March 2016 to December 2018, 147 patients with suspected vertebrobasilar artery stenosis admitted to the People's Hospital of Zhuji were selected.TCD combined with carotid artery ultrasonography were used to diagnose vertebrobasilar artery stenosis, and X-ray computed tomography angiography (CTA) was performed.The diagnostic accuracy of TCD combined with carotid artery ultrasonography for vertebrobasilar artery stenosis was analyzed based on the results of CTA. Results The diagnostic value of TCD combined with carotid ultrasound for vertebrobasilar artery stenosis was analyzed by using CTA as diagnostic gold standard.The diagnostic sensitivity for left vertebral artery was 86.42%, specificity was 89.39%, positive predictive value was 90.91%, negative predictive value was 84.29%.The diagnostic sensitivity for right vertebral artery was 80.26%, specificity was 90.14%, positive predictive value was 89.71%, negative predictive value was 81.01%.The sensitivity, specificity, positive predictive value and negative predictive value for basilar artery were 81.69%, 93.42%, 92.06% and 84.52%.respectively.There were no statistically significant differences between TCD combined with carotid ultrasound and CTA in the diagnosis of left vertebral artery, right vertebral artery and basilar artery stenosis (Z=-0.360, -0.851, -0.828, all P>0.05). Conclusion TCD combined with carotid ultrasonography is an effective screening method for patients with vertebrobasilar artery stenosis, which is helpful to the detection of patients' condition and the guidance of clinical treatment, and is worthy of clinical application. Key words: Ultrasonography, doppler, transcranial; Ultrasonography, doppler, color; Basilar artery; Vertebral artery; Carotid arteries; X-ray computed tomography angiography; Intracranial atherosclerotic stenosis
{"title":"Clinical value of transcranial Doppler ultrasonography combined with carotid ultrasonography in the diagnosis of vertebral-basilar artery stenosis","authors":"Jie-Wei Wang","doi":"10.3760/CMA.J.ISSN.1008-6706.2020.07.005","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1008-6706.2020.07.005","url":null,"abstract":"Objective \u0000To investigate the clinical value of transcranial Doppler ultrasound(TCD) combined with carotid ultrasound in the diagnosis of vertebral-basilar artery stenosis. \u0000 \u0000 \u0000Methods \u0000From March 2016 to December 2018, 147 patients with suspected vertebrobasilar artery stenosis admitted to the People's Hospital of Zhuji were selected.TCD combined with carotid artery ultrasonography were used to diagnose vertebrobasilar artery stenosis, and X-ray computed tomography angiography (CTA) was performed.The diagnostic accuracy of TCD combined with carotid artery ultrasonography for vertebrobasilar artery stenosis was analyzed based on the results of CTA. \u0000 \u0000 \u0000Results \u0000The diagnostic value of TCD combined with carotid ultrasound for vertebrobasilar artery stenosis was analyzed by using CTA as diagnostic gold standard.The diagnostic sensitivity for left vertebral artery was 86.42%, specificity was 89.39%, positive predictive value was 90.91%, negative predictive value was 84.29%.The diagnostic sensitivity for right vertebral artery was 80.26%, specificity was 90.14%, positive predictive value was 89.71%, negative predictive value was 81.01%.The sensitivity, specificity, positive predictive value and negative predictive value for basilar artery were 81.69%, 93.42%, 92.06% and 84.52%.respectively.There were no statistically significant differences between TCD combined with carotid ultrasound and CTA in the diagnosis of left vertebral artery, right vertebral artery and basilar artery stenosis (Z=-0.360, -0.851, -0.828, all P>0.05). \u0000 \u0000 \u0000Conclusion \u0000TCD combined with carotid ultrasonography is an effective screening method for patients with vertebrobasilar artery stenosis, which is helpful to the detection of patients' condition and the guidance of clinical treatment, and is worthy of clinical application. \u0000 \u0000 \u0000Key words: \u0000Ultrasonography, doppler, transcranial; Ultrasonography, doppler, color; Basilar artery; Vertebral artery; Carotid arteries; X-ray computed tomography angiography; Intracranial atherosclerotic stenosis","PeriodicalId":10226,"journal":{"name":"Chinese Journal of Primary Medicine and Pharmacy","volume":"27 1","pages":"786-790"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43955926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-04-01DOI: 10.3760/CMA.J.ISSN.1008-6706.2020.07.010
Jinhua Chen, Yilin Zhang
Objective To investigate the relationship between plasma N-terminal B-type natriuretic peptide precursor (NT-proBNP), hypersensitive C-reactive protein (hs-CRP), troponin Ⅰ (cTnⅠ) and carbohydrate antigen 125 (CA125) and cardiac function in patients with acute heart failure. Methods From May 2017 to May 2019, 97 patients with acute heart failure admitted to Hangzhou Dajiangdong Hospital were selected as the observation group.According to the cardiac function classification of New York Heart Association (NYHA), 29 patients were classified as grade Ⅱ group, 51 patients as grade Ⅲ group and 17 patients as grade Ⅳ group.Fifty healthy people were selected as control group.The changes of plasma NT-proBNP, hs-CRP, cTnⅠ and CA125 levels, left ventricular end-diastolic diameter (LVEDD) and left ventricular ejection fraction (LVEF) were compared between the two groups.The changes of plasma NT-proBNP, hs-CRP, cTnⅠ and CA125 levels, as well as the changes of LVED and LVEF in the different heart function grading group were compared.The correlation between plasma NT-proBNP, hs-CRP, cTnⅠ, CA125 and LVEDD, LVEF was analyzed. Results The plasma NT-proBNP[(5 684.21±174.39)ng/L], hs-CRP[(16.54±3.27)mg/L], cTnⅠ[(0.43±0.13)g/L] and CA125[(83.24±15.46)U/mL] in the observation group were higher than those in the control group(t=216.813, 25.684, 19.432, 34.138, all P<0.05). The LVEDD in the observation group[(63.21±4.87)mm] was higher than that in the control group[(48.97±2.41)mm], and the LVEFin the observation group[(39.27±3.25)%] was lower than that in the control group[(62.87±4.36)%], the differences were statistically significant (t=19.461, 37.008, all P<0.05). The levels of NT-proBNP[(7 368.18±201.05)ng/L], hs-CRP[(24.19±4.18)mg/L], cTnⅠ[(0.63±0.14)μg/L] and CA125[(164.52±27.48)U/mL] in the grade Ⅳ group were higher than those in the grade Ⅱ group and grade Ⅲ group(grade Ⅲ group: t=31.109, 6.557, 5.321, 13.017; grade Ⅱ group: t=75.873, 16.582, 11.755, 23.178, all P<0.05). The plasma NT-proBNP[(5 751.42±180.34)ng/L], hs-CRP[(15.98±4.56)mg/L], cTnⅠ[(0.41±0.15)g/L] and CA125[(87.97±18.45)U/mL] in the grade Ⅲ group were higher than those in the grade Ⅱ group[(3 481.34±145.26)ng/L, (8.23±2.37)mg/L, (0.25±0.08)μg/L and (28.43±12.21)U/mL](t=57.893, 8.507, 5.320, 15.530, all P<0.05). The LVEDD[(67.95±5.15)mm] in the grade Ⅳ group was higher than that in the grade Ⅱ group and grade Ⅲ group(grade Ⅲ group: t=3.553, grade Ⅱ group: t=8.157, P<0.05), while the LVEF[(34.28±2.36)%] in the grade Ⅳ group was lower than that in the grade Ⅱ group and grade Ⅲ group(grade Ⅲ group: t=6.673, grade Ⅱ group: t=10.417, all P<0.05). The LVEDD[(62.78±5.21)mm] in the grade Ⅲ group was higher than that in the grade Ⅱ group[(57.87±3.25)mm](t=4.586, P<0.05), while the LVEF in the grade Ⅲ group[(39.98±3.24)%] was lower than that in the grade Ⅱ group[(45.98±4.25)%](t=7.097, P<0.05). LVEDD was positively correlated with NT-proBNP, hs-CRP, cTnⅠ and CA125, while LVEF was negatively correl
{"title":"Analysis of the correlation between plasma NT-proBNP, hs-CRP, cTnI, CA125 and cardiac function in patients with acute heart failure","authors":"Jinhua Chen, Yilin Zhang","doi":"10.3760/CMA.J.ISSN.1008-6706.2020.07.010","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1008-6706.2020.07.010","url":null,"abstract":"Objective \u0000To investigate the relationship between plasma N-terminal B-type natriuretic peptide precursor (NT-proBNP), hypersensitive C-reactive protein (hs-CRP), troponin Ⅰ (cTnⅠ) and carbohydrate antigen 125 (CA125) and cardiac function in patients with acute heart failure. \u0000 \u0000 \u0000Methods \u0000From May 2017 to May 2019, 97 patients with acute heart failure admitted to Hangzhou Dajiangdong Hospital were selected as the observation group.According to the cardiac function classification of New York Heart Association (NYHA), 29 patients were classified as grade Ⅱ group, 51 patients as grade Ⅲ group and 17 patients as grade Ⅳ group.Fifty healthy people were selected as control group.The changes of plasma NT-proBNP, hs-CRP, cTnⅠ and CA125 levels, left ventricular end-diastolic diameter (LVEDD) and left ventricular ejection fraction (LVEF) were compared between the two groups.The changes of plasma NT-proBNP, hs-CRP, cTnⅠ and CA125 levels, as well as the changes of LVED and LVEF in the different heart function grading group were compared.The correlation between plasma NT-proBNP, hs-CRP, cTnⅠ, CA125 and LVEDD, LVEF was analyzed. \u0000 \u0000 \u0000Results \u0000The plasma NT-proBNP[(5 684.21±174.39)ng/L], hs-CRP[(16.54±3.27)mg/L], cTnⅠ[(0.43±0.13)g/L] and CA125[(83.24±15.46)U/mL] in the observation group were higher than those in the control group(t=216.813, 25.684, 19.432, 34.138, all P<0.05). The LVEDD in the observation group[(63.21±4.87)mm] was higher than that in the control group[(48.97±2.41)mm], and the LVEFin the observation group[(39.27±3.25)%] was lower than that in the control group[(62.87±4.36)%], the differences were statistically significant (t=19.461, 37.008, all P<0.05). The levels of NT-proBNP[(7 368.18±201.05)ng/L], hs-CRP[(24.19±4.18)mg/L], cTnⅠ[(0.63±0.14)μg/L] and CA125[(164.52±27.48)U/mL] in the grade Ⅳ group were higher than those in the grade Ⅱ group and grade Ⅲ group(grade Ⅲ group: t=31.109, 6.557, 5.321, 13.017; grade Ⅱ group: t=75.873, 16.582, 11.755, 23.178, all P<0.05). The plasma NT-proBNP[(5 751.42±180.34)ng/L], hs-CRP[(15.98±4.56)mg/L], cTnⅠ[(0.41±0.15)g/L] and CA125[(87.97±18.45)U/mL] in the grade Ⅲ group were higher than those in the grade Ⅱ group[(3 481.34±145.26)ng/L, (8.23±2.37)mg/L, (0.25±0.08)μg/L and (28.43±12.21)U/mL](t=57.893, 8.507, 5.320, 15.530, all P<0.05). The LVEDD[(67.95±5.15)mm] in the grade Ⅳ group was higher than that in the grade Ⅱ group and grade Ⅲ group(grade Ⅲ group: t=3.553, grade Ⅱ group: t=8.157, P<0.05), while the LVEF[(34.28±2.36)%] in the grade Ⅳ group was lower than that in the grade Ⅱ group and grade Ⅲ group(grade Ⅲ group: t=6.673, grade Ⅱ group: t=10.417, all P<0.05). The LVEDD[(62.78±5.21)mm] in the grade Ⅲ group was higher than that in the grade Ⅱ group[(57.87±3.25)mm](t=4.586, P<0.05), while the LVEF in the grade Ⅲ group[(39.98±3.24)%] was lower than that in the grade Ⅱ group[(45.98±4.25)%](t=7.097, P<0.05). LVEDD was positively correlated with NT-proBNP, hs-CRP, cTnⅠ and CA125, while LVEF was negatively correl","PeriodicalId":10226,"journal":{"name":"Chinese Journal of Primary Medicine and Pharmacy","volume":"27 1","pages":"808-812"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43982926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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