Pub Date : 2000-04-15DOI: 10.3760/CMA.J.ISSN.1673-4904.2000.04.009
S. Yong
Objective:To investigate the therapeutic outcome and effect of Clindamycin Phosphate in the treatment of successive lung infection with anaerobic bacteria after radiotherapy.Materials and Methods:78 patients with malignancy contracting successive lung infection with anaerobic bacteria followed by radiotherapy were randomly divided into 2 groups,41 people (Clindamycin Phosphate treatment group) and 37 people (Miediling control group) Clindamycin phosphate,300～600 mg,Bid or Tid,10～14 days,Miediling 500～750 mg.Bid or once/8h,10～14 days.Result:(1)Both recovery and efficacious rate demonstratd a significant difference respectively between treatment group and control group(68.3% vs 45.9%) (P0.05),(80.5% vs 59.5%)(P0.05);(2)There existed a significant difference in the lethal rate to the bacteria between treatment group and control group(75.6% vs 54.1%)(P0.05);(3)Side effect incidence rate were 22% and 45.9% selarately (P0.05).Conclusion:The application of clindamycin phosphate in the treatment of successive lung infection with anaerobic bacteria after radiotherapy displayed a better effect and smaller side effect.
{"title":"RESEARCH OF THE APPLICATION OF CLINDAMYCIN PHOSPHATE IN THE SUCCESSIVE LUNG INFECTION WITH ANAEROBIC BACTERIA AFTER RADIOTHERAPY","authors":"S. Yong","doi":"10.3760/CMA.J.ISSN.1673-4904.2000.04.009","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1673-4904.2000.04.009","url":null,"abstract":"Objective:To investigate the therapeutic outcome and effect of Clindamycin Phosphate in the treatment of successive lung infection with anaerobic bacteria after radiotherapy.Materials and Methods:78 patients with malignancy contracting successive lung infection with anaerobic bacteria followed by radiotherapy were randomly divided into 2 groups,41 people (Clindamycin Phosphate treatment group) and 37 people (Miediling control group) Clindamycin phosphate,300～600 mg,Bid or Tid,10～14 days,Miediling 500～750 mg.Bid or once/8h,10～14 days.Result:(1)Both recovery and efficacious rate demonstratd a significant difference respectively between treatment group and control group(68.3% vs 45.9%) (P0.05),(80.5% vs 59.5%)(P0.05);(2)There existed a significant difference in the lethal rate to the bacteria between treatment group and control group(75.6% vs 54.1%)(P0.05);(3)Side effect incidence rate were 22% and 45.9% selarately (P0.05).Conclusion:The application of clindamycin phosphate in the treatment of successive lung infection with anaerobic bacteria after radiotherapy displayed a better effect and smaller side effect.","PeriodicalId":10229,"journal":{"name":"Chinese Journal of Postgraduates of Medicine","volume":"97 1","pages":"19-21"},"PeriodicalIF":0.0,"publicationDate":"2000-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73606987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2000-03-15DOI: 10.3760/CMA.J.ISSN.1673-4904.2000.03.012
Xuebing Feng
Objective:To evaluate the clinical features and correlation with disease course of mixed connective tissue disease (MCTD).Methods:30 patients with definite MCTD were analyzed retropectively by their clinical manifestation and immunological features,treatments and prognosis.They were assigned to two groups according to their courses of the disease (group A5 years and group B ≥5 years).Results:The primarily incipient symptoms of MCTD were Raynaud's phenomenon and arthralgia/arthritis.Morbidity of Raynaud's phenomenon in group A was statistically significantly higher than in group B(P0.01) while incidence of pulmonary hypertension or interstitial fibrosis was higher in group B (P0.05).Laboratroy indices showed that abnormal IgG and ESR were easy to be seen and renal dysfunction with high uria protein was found in 26.7% patients.Mortality was zero in group A while 25% in group B.Conclusion:MCTD is not a benign disease.With disease duration prolonged,incidence of vital organ dysfunction increases and mortality tends to elevate.
{"title":"THE CLINICAL ANALYSIS OF MIXED CONNECFIVE TISSUE DISEASE:A REPORT OF 30 CASES","authors":"Xuebing Feng","doi":"10.3760/CMA.J.ISSN.1673-4904.2000.03.012","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1673-4904.2000.03.012","url":null,"abstract":"Objective:To evaluate the clinical features and correlation with disease course of mixed connective tissue disease (MCTD).Methods:30 patients with definite MCTD were analyzed retropectively by their clinical manifestation and immunological features,treatments and prognosis.They were assigned to two groups according to their courses of the disease (group A5 years and group B ≥5 years).Results:The primarily incipient symptoms of MCTD were Raynaud's phenomenon and arthralgia/arthritis.Morbidity of Raynaud's phenomenon in group A was statistically significantly higher than in group B(P0.01) while incidence of pulmonary hypertension or interstitial fibrosis was higher in group B (P0.05).Laboratroy indices showed that abnormal IgG and ESR were easy to be seen and renal dysfunction with high uria protein was found in 26.7% patients.Mortality was zero in group A while 25% in group B.Conclusion:MCTD is not a benign disease.With disease duration prolonged,incidence of vital organ dysfunction increases and mortality tends to elevate.","PeriodicalId":10229,"journal":{"name":"Chinese Journal of Postgraduates of Medicine","volume":"27 1","pages":"26-28"},"PeriodicalIF":0.0,"publicationDate":"2000-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81322762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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