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DIAGNOSIS AND TREATMENT FOR BUDD-CHIARI SYNDROME ACCOMPANIED BY THROMBOGENESIS OF INFERIOR VENA CAVA 布-恰利综合征伴下腔静脉血栓形成的诊断与治疗
Pub Date : 2000-10-15 DOI: 10.3760/CMA.J.ISSN.1673-4904.2000.10.008
Long-shuan Zhao, Yong-fu Zhao
Objective:To explore effective methods of diagnosis and treatment in Budd-Chiari syndrome accompanied by thrombogenesis of inferior vena cava.Methods:43 patients were diagnosed and treated from May 1983 to December 1998.Results:42 cases were treated by operation,one by percutaneous transluminal angioplasty.Thromboembolism of pulmonary artery were presented in 6 cases,4 cases of them were cured by drugs and 2 cases died.Conclusion:The combination of color Doppler songraphy and phlebography of IVC and percutaneous transhepatic hepatovenography can distinguish thrombosis of IVC for patients with Budd-Chiari syndrome.It is the main therapy to open IVC and take out thrombosis by operation.
目的:探讨Budd-Chiari综合征合并下腔静脉血栓形成的有效诊断和治疗方法。方法:1983年5月~ 1998年12月诊治43例。结果:手术治疗42例,经皮腔内血管成形术1例。出现肺动脉血栓栓塞6例,经药物治疗治愈4例,死亡2例。结论:彩色多普勒超声联合下腔静脉造影及经皮经肝肝静脉造影可鉴别Budd-Chiari综合征患者下腔静脉血栓形成。目前主要的治疗方法是打开下腔静脉,通过手术清除血栓。
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引用次数: 0
THE CLINICAL CHARACTER OF INFECTIVE ENDOCARDITIS AND THE DIAGNOSTIC VALUE OF ECHOCARDIOGRAPHY 感染性心内膜炎的临床特点及超声心动图的诊断价值
Pub Date : 2000-09-15 DOI: 10.3760/CMA.J.ISSN.1673-4904.2000.09.010
A. Sun, J. Hui, Jun-hua Yang, Su-dan Xu, Huifeng Wang
Objective:To study the clinical character of infective endocarditis (IE) and the diagnostic value of echocardiography to IE.Methods:The clinical and echocardiographic information of 78 patients was analysed.Results:Basic heart diseases in 66 patients (84.6%) and vegetations in 51 patients (65.4%) were found.A total of 65 blood bacterial culture studies were porformed,and positive only in 16 cases (24.6%).The incidence of fever,enlarged spleen,embolism and death was 83.8%,52.6%,19.2% and 9.0% respectively.Conclusion:The decrease of positive blood culture and lack of typical symptoms make it diffcult to diagnose IE and then delay treatment.Echocardiography can provide etiological and pathological diagnose for IE.As a valuable tool,it can also assess the complications and prognosis.
目的:探讨感染性心内膜炎(IE)的临床特点及超声心动图对IE的诊断价值。方法:对78例患者的临床及超声心动图资料进行分析。结果:基础心脏病66例(84.6%),植被51例(65.4%)。共进行65例血细菌培养,阳性16例(24.6%)。发热、脾肿大、栓塞和死亡的发生率分别为83.8%、52.6%、19.2%和9.0%。结论:血培养阳性患者减少,缺乏典型症状,使IE难以诊断,延误治疗。超声心动图可提供IE的病因和病理诊断。作为一种有价值的工具,它还可以评估并发症和预后。
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引用次数: 0
CLINICAL CHARACTERISTICS OF RIGHT-SIDED STAPHYLOCOCCUS AUREUS ENDOCARDITIS 右侧金黄色葡萄球菌心内膜炎的临床特点
Pub Date : 2000-09-15 DOI: 10.3760/CMA.J.ISSN.1673-4904.2000.09.009
Qing-xiang Liang, L. Luo, Xiang-guang Xu, Jin-cheng Xu
Objective:To evaluate the clinical characteristics of right|sided staphylococcus aureus endocarditis(RSAE).Methods:The clinical data in 18 cases with RSAE was retrospectively analyzed.Results:It showed that in 18 cases with RSAE,12 cases without organic heart diseases previously,and 9 of the 12 cases were intravenous drug users,and 18 cases with cough,yellow purulent sputum or blood sputum,and can be heard with little and media moist rale over the two lungs,and their blood culture confirmed to grow with staphylococcus aureus two or more than two times,chest roentgenography discovered with patch or multiple nodule shadow over the two lung fields,and 6 cases found with cavity formation,2 cases with empyema.It need 25.3(14~72) days in average to discover the vegetation on right heart valves or endocardium confirmed in UCG test from the onset of the disease.Conclusions:X-film manifestations for pulmonary acute inflammation or multiple pulmonary abscess,and new regurgitation murmur over the tricuspid valves or pulmonary valve during the course,were all significant for RSAE diagnosis,Doppler ultrasonic examination was also important for RSAE diagnosis,but may be negative in the early stage,therefore,these suspected cases should be given a dynamic observation.
目的:探讨右脑侧金黄色葡萄球菌心内膜炎(RSAE)的临床特点。方法:回顾性分析18例RSAE患者的临床资料。结果:它表明与RSAE 18例,12例没有有机心脏病之前,和9 12例静脉注射毒品使用者,和18例咳嗽,黄色脓性痰或血痰,和可以听到小和媒体两个肺部湿罗音,和他们的血培养证实与金黄色葡萄球菌生长两个或两个以上的时候,胸部x线照相术发现补丁或多个结节阴影两肺字段,和6例发现腔形成,2例伴有脓胸。从发病开始,平均需要25.3(14~72)天才能发现经UCG检查确认的右心瓣膜或心内膜赘生物。结论:肺急性炎症或多发肺脓肿的x片表现,以及病程中三尖瓣或肺瓣上新发反流性杂音,均对RSAE诊断有重要意义,多普勒超声检查对RSAE诊断也有重要意义,但早期可能呈阴性,对疑似病例应进行动态观察。
{"title":"CLINICAL CHARACTERISTICS OF RIGHT-SIDED STAPHYLOCOCCUS AUREUS ENDOCARDITIS","authors":"Qing-xiang Liang, L. Luo, Xiang-guang Xu, Jin-cheng Xu","doi":"10.3760/CMA.J.ISSN.1673-4904.2000.09.009","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1673-4904.2000.09.009","url":null,"abstract":"Objective:To evaluate the clinical characteristics of right|sided staphylococcus aureus endocarditis(RSAE).Methods:The clinical data in 18 cases with RSAE was retrospectively analyzed.Results:It showed that in 18 cases with RSAE,12 cases without organic heart diseases previously,and 9 of the 12 cases were intravenous drug users,and 18 cases with cough,yellow purulent sputum or blood sputum,and can be heard with little and media moist rale over the two lungs,and their blood culture confirmed to grow with staphylococcus aureus two or more than two times,chest roentgenography discovered with patch or multiple nodule shadow over the two lung fields,and 6 cases found with cavity formation,2 cases with empyema.It need 25.3(14~72) days in average to discover the vegetation on right heart valves or endocardium confirmed in UCG test from the onset of the disease.Conclusions:X-film manifestations for pulmonary acute inflammation or multiple pulmonary abscess,and new regurgitation murmur over the tricuspid valves or pulmonary valve during the course,were all significant for RSAE diagnosis,Doppler ultrasonic examination was also important for RSAE diagnosis,but may be negative in the early stage,therefore,these suspected cases should be given a dynamic observation.","PeriodicalId":10229,"journal":{"name":"Chinese Journal of Postgraduates of Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2000-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86079059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
DETECTION AND ITS CLINICAL SIGNIFICANCE OF FIBRINOGEN-BOUND SIALIC LEVELS IN PATIENTS WITH LIVER DISEASE 肝病患者纤维蛋白原结合唾液水平的检测及其临床意义
Pub Date : 2000-08-15 DOI: 10.3760/CMA.J.ISSN.1673-4904.2000.08.010
Jian Li, Yu-gui Zhou, Guoyong Ding, Zheng Zhu
Objective:To explore the clinical significance of fibrinogen-bound sialic acid levels in patients with liver disease.Methods:Fibrinogen was purified by precipitation from citrated plasma by saturated ammonium sulplvate.Fibrinogen-bound sialic acid levels with 22 controls and 113 liver patients were assayed by the thiobarbituric acid method.Results:The level of the patients with liver cirrhosis was significantly higher than that of the controls and others liver disease group (P0.01).In addition there was relationship between the thrombin time and fibrinogen-bound sialic acid contents.Poly merization of fibrin monomer was inverse ratio with fibrinogen-bound sialic acid.Conclusion:It suggests that fibrinogen-bound sialic acid levels may be diagnostic index acquired dysfibrinogenaemia.
目的:探讨肝脏疾病患者纤维蛋白原结合唾液酸水平的临床意义。方法:用饱和硫酸铵沉淀法纯化柠檬酸血浆中的纤维蛋白原。用硫代巴比妥酸法测定22例对照组和113例肝脏患者纤维蛋白原结合唾液酸水平。结果:肝硬化组患者血清血清素水平明显高于对照组及其他肝病组(P0.01)。凝血酶时间与纤维蛋白原结合唾液酸含量之间存在相关性。纤维蛋白单体的聚合与纤维蛋白原结合的唾液酸成反比。结论:纤维蛋白原结合唾液酸水平可作为获得性纤维蛋白异常血症的诊断指标。
{"title":"DETECTION AND ITS CLINICAL SIGNIFICANCE OF FIBRINOGEN-BOUND SIALIC LEVELS IN PATIENTS WITH LIVER DISEASE","authors":"Jian Li, Yu-gui Zhou, Guoyong Ding, Zheng Zhu","doi":"10.3760/CMA.J.ISSN.1673-4904.2000.08.010","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1673-4904.2000.08.010","url":null,"abstract":"Objective:To explore the clinical significance of fibrinogen-bound sialic acid levels in patients with liver disease.Methods:Fibrinogen was purified by precipitation from citrated plasma by saturated ammonium sulplvate.Fibrinogen-bound sialic acid levels with 22 controls and 113 liver patients were assayed by the thiobarbituric acid method.Results:The level of the patients with liver cirrhosis was significantly higher than that of the controls and others liver disease group (P0.01).In addition there was relationship between the thrombin time and fibrinogen-bound sialic acid contents.Poly merization of fibrin monomer was inverse ratio with fibrinogen-bound sialic acid.Conclusion:It suggests that fibrinogen-bound sialic acid levels may be diagnostic index acquired dysfibrinogenaemia.","PeriodicalId":10229,"journal":{"name":"Chinese Journal of Postgraduates of Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2000-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73541786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CORRELATION BETWEEN ICG AND CHILD-PUGH CLASSIFICATION IN PATIENTS WITH LIVER CIRRHOSIS 肝硬化患者icg与child-pugh分型的关系
Pub Date : 2000-08-15 DOI: 10.3760/CMA.J.ISSN.1673-4904.2000.08.008
Xiao-lan Zhang, F. Shao, Zhi-qing Zhang, Yu-zhuo Zhang, Hong-tao Jin
Objective:To study the correlation between ICG and Child-Pugh classification in patients with liver cirrhosis.Methods:The levels of ICG were measured in 58 patients with cirrhosis and 32 normal controls.Results:The levels of ICG were significantly higher in patients with cirrhosis (23.12%±3.98%) than in controls (2.23%±1.47%),P0.01.Comparisons of the levels of ICG in group of patients with different liver function were shown as follows:Child-Pugh Cchild-Pugh BChild-Pugh A.There was positive correlation between ICG and Child-Pugh classification as well as BIL,but there was not correlation between ICG and albumin as well as PA.Conclusion:The increase of ICG is closely associated with the severity of liver cirrhosis and the ICG is suitable for objective analysis of Child-Pugh classification.
目的:探讨肝硬化患者ICG与Child-Pugh分型的相关性。方法:测定58例肝硬化患者和32例正常人的ICG水平。结果:肝硬化组ICG水平(23.12%±3.98%)明显高于对照组(2.23%±1.47%),p < 0.01。不同肝功能组患者ICG水平比较如下:Child-Pugh Child-Pugh BChild-Pugh a . ICG与Child-Pugh分型、BIL呈正相关,与白蛋白、PA无相关性。结论:ICG的升高与肝硬化的严重程度密切相关,ICG适合Child-Pugh分型的客观分析。
{"title":"CORRELATION BETWEEN ICG AND CHILD-PUGH CLASSIFICATION IN PATIENTS WITH LIVER CIRRHOSIS","authors":"Xiao-lan Zhang, F. Shao, Zhi-qing Zhang, Yu-zhuo Zhang, Hong-tao Jin","doi":"10.3760/CMA.J.ISSN.1673-4904.2000.08.008","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1673-4904.2000.08.008","url":null,"abstract":"Objective:To study the correlation between ICG and Child-Pugh classification in patients with liver cirrhosis.Methods:The levels of ICG were measured in 58 patients with cirrhosis and 32 normal controls.Results:The levels of ICG were significantly higher in patients with cirrhosis (23.12%±3.98%) than in controls (2.23%±1.47%),P0.01.Comparisons of the levels of ICG in group of patients with different liver function were shown as follows:Child-Pugh Cchild-Pugh BChild-Pugh A.There was positive correlation between ICG and Child-Pugh classification as well as BIL,but there was not correlation between ICG and albumin as well as PA.Conclusion:The increase of ICG is closely associated with the severity of liver cirrhosis and the ICG is suitable for objective analysis of Child-Pugh classification.","PeriodicalId":10229,"journal":{"name":"Chinese Journal of Postgraduates of Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2000-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76660687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
EVALUATION OF ABSOLUTE ALCOHOL TREATMENT FOR RENAL CYST BY PERCUTANEOUS PUNCTURE UNDER ULTRASONOGRAPHIC GUIDANCE 超声引导下经皮穿刺无水酒精治疗肾囊肿疗效评价
Pub Date : 2000-08-15 DOI: 10.3760/CMA.J.ISSN.1673-4904.2000.08.015
F. Jiang, Hou-bao Huang
Objective:To observe therapeutic effect with absolute alcohol treatment for 118 cases renal cyst by percutaneous puncture under ultrasonographic guidance.Methods:With transrenal aspiration of the encased fluid followed by injection of pure ethanol into the lumen.Results:After absolute alcohol treatment for 173 cysts in 118 cases,cure rate 87.28%,markedly effective rate 96.53%,effective rate 99.42%.Conclusion:This method is effective,safe and accurate,simple and economy.
目的:观察超声引导下经皮穿刺无水酒精治疗肾囊肿118例的疗效。方法:经肾抽吸包膜液,再向管腔内注射纯乙醇。结果:无水酒精治疗173例囊肿118例,治愈率87.28%,显有效率96.53%,有效率99.42%。结论:该方法有效、安全、准确、简便、经济。
{"title":"EVALUATION OF ABSOLUTE ALCOHOL TREATMENT FOR RENAL CYST BY PERCUTANEOUS PUNCTURE UNDER ULTRASONOGRAPHIC GUIDANCE","authors":"F. Jiang, Hou-bao Huang","doi":"10.3760/CMA.J.ISSN.1673-4904.2000.08.015","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1673-4904.2000.08.015","url":null,"abstract":"Objective:To observe therapeutic effect with absolute alcohol treatment for 118 cases renal cyst by percutaneous puncture under ultrasonographic guidance.Methods:With transrenal aspiration of the encased fluid followed by injection of pure ethanol into the lumen.Results:After absolute alcohol treatment for 173 cysts in 118 cases,cure rate 87.28%,markedly effective rate 96.53%,effective rate 99.42%.Conclusion:This method is effective,safe and accurate,simple and economy.","PeriodicalId":10229,"journal":{"name":"Chinese Journal of Postgraduates of Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2000-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80822779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THE MEASUREMENT AND CLINICAL SIGNIFICANCE OF NEURON-SPECIFIC ENOLASE IN PATIENTS WITH HEPATOENCEPHALOPATHY 肝脑病患者神经元特异性烯醇化酶的测定及临床意义
Pub Date : 2000-08-15 DOI: 10.3760/CMA.J.ISSN.1673-4904.2000.08.009
Guanghao Zhang, Q. Jin
Objective:To study the clinical significance of neuron|specific enolase (NSE) in the patients with hepatoencephalopathy(HE).Methods:The serum NSE was measured by ELISA in 46 cases.The results were analyzed in every clinical type liver disease and every stage of HE.Results:The serum NSE levels was significantly increased in the patients with HE (46.038±24.260) μg/L compared with the patients with chronic hepatitis (12.127±5.673) μg/L and control cases (10.196±3.237) μg/L.The serum NSE levels gradually increased (P0.05) in the patients with liver cirrhosis,subacute fatal hepatitis and acute fatal hepatitis,and the serum NSE levels was obviously higher in patients with the fourth stage HE than they with first and second stage.Conclusion:The serume NSE levels obviously increased in the patients with HE,and it gradually increased in the patients with liver cirrhosis,subacute fatal hepatitis and acute fatal hepatitis.The serum NSE levels were higher in the patients with more serious HE.
目的:探讨神经元特异性烯醇化酶(NSE)在肝性脑病(HE)患者中的临床意义。方法:采用ELISA法测定46例患者血清NSE。分析肝脏疾病各临床类型及HE分期的结果。结果:HE患者血清NSE水平(46.038±24.260)μg/L明显高于慢性肝炎患者(12.127±5.673)μg/L和对照组(10.196±3.237)μg/L。肝硬化、亚急性致死性肝炎和急性致死性肝炎患者血清NSE水平逐渐升高(P0.05),且HE四期患者血清NSE水平明显高于ⅰ、ⅱ期患者。结论:HE患者血清NSE水平明显升高,肝硬化、亚急性致死性肝炎和急性致死性肝炎患者血清NSE水平逐渐升高。HE越严重,血清NSE水平越高。
{"title":"THE MEASUREMENT AND CLINICAL SIGNIFICANCE OF NEURON-SPECIFIC ENOLASE IN PATIENTS WITH HEPATOENCEPHALOPATHY","authors":"Guanghao Zhang, Q. Jin","doi":"10.3760/CMA.J.ISSN.1673-4904.2000.08.009","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1673-4904.2000.08.009","url":null,"abstract":"Objective:To study the clinical significance of neuron|specific enolase (NSE) in the patients with hepatoencephalopathy(HE).Methods:The serum NSE was measured by ELISA in 46 cases.The results were analyzed in every clinical type liver disease and every stage of HE.Results:The serum NSE levels was significantly increased in the patients with HE (46.038±24.260) μg/L compared with the patients with chronic hepatitis (12.127±5.673) μg/L and control cases (10.196±3.237) μg/L.The serum NSE levels gradually increased (P0.05) in the patients with liver cirrhosis,subacute fatal hepatitis and acute fatal hepatitis,and the serum NSE levels was obviously higher in patients with the fourth stage HE than they with first and second stage.Conclusion:The serume NSE levels obviously increased in the patients with HE,and it gradually increased in the patients with liver cirrhosis,subacute fatal hepatitis and acute fatal hepatitis.The serum NSE levels were higher in the patients with more serious HE.","PeriodicalId":10229,"journal":{"name":"Chinese Journal of Postgraduates of Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2000-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88855385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THE CLINICAL DIAGNOSIS AND OPERATION MANAGEMENT OF STRANGULATING INTESTINAL OBSTRUCTION IN 139 CASES 139例绞窄性肠梗阻的临床诊断与手术处理
Pub Date : 2000-08-15 DOI: 10.3760/CMA.J.ISSN.1673-4904.2000.08.012
Xueying Chen, Rong-lin Yan, Xing Yang, Wen-yuan Guo, Weiyuan Zhang
Objective: To investigate the early diagnosis and operative manner of strangulating intestinal obstruction. Methods: The clinical material of 139 patients with strangulating intestinal obstruction from Jan. 1975 to Dec. 1999 was analysed retrospectively. Results: There were only 58 patients(41.7%) were diagnosed as strangulating intestinal obstruction before operation, the other 81 patients(58.3%) were diagnosed at laparotomy. All patients were treated by operation, 106 patients were cured, 33 dead. The mortality was 23.7%. The main cause of death was septic shock、MOF、ARDS and severe disturbance of water-electrolyte、acid-base balance. Conclusion: Early diagnosis of strangulating intestinal obstruction was difficult. Intestine necrosis may be prevented by analysing carefully the clinical features and related examinations. Early operation was the most effective treatment. Emphasized post operative ICU management was the key procedure of decreasing mortality.
目的:探讨绞窄性肠梗阻的早期诊断及手术方式。方法:回顾性分析我院1975年1月~ 1999年12月收治的139例绞窄性肠梗阻患者的临床资料。结果:术前诊断为绞窄性肠梗阻的患者58例(41.7%),开腹诊断为绞窄性肠梗阻的患者81例(58.3%)。所有患者均行手术治疗,治愈106例,死亡33例。死亡率为23.7%。死亡原因主要为感染性休克、MOF、ARDS及严重的水电解质、酸碱平衡紊乱。结论:绞窄性肠梗阻早期诊断困难。通过仔细分析临床特征和相关检查,可以预防肠坏死。早期手术是最有效的治疗方法。强调术后ICU管理是降低死亡率的关键环节。
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引用次数: 0
OPERATION OF INDICATION AND METHODS OF TRAUMATIC CEREBRAL EXTERNAL FLUID ACCUMULATIVE 外伤性脑外积液的手术适应证及方法
Pub Date : 2000-07-15 DOI: 10.3760/CMA.J.ISSN.1673-4904.2000.07.011
Shao-qin Zheng, Ying-ming Yang
Objective:To detect the operation indication and methods of traumatic cerebral external fluid accumulative (TCEFA).Methods:The clinical characters,feature of CT scan and MRI and to determine the protein contain of fluid were analysis,according to the 27 cases and uses different operation to cure.Results:Operation respectively with fluid-peritoneal cavity shunts 16 cases,bores hole drainage 6 cases,fontanel drainage 3 and puncture in 4.Twenty-five cases gets recover entirely and 2 cases abandon cure.Conclusion:The operation of indication dependent on the clinical disease that quantity accumulating liquid and patient's signs and symptoms,but the method is decided by nature (composition of accumulating liquid).And that the protein content is high or gets along with blood,and Drainage outside the line or aspirates through the fontanel;opposite,fluid-peritoneal cavity shunt should done.
目的:探讨外伤性脑外积液(TCEFA)的手术适应证和方法。方法:对27例患者的临床表现、CT、MRI表现及体液蛋白含量进行分析,并采用不同的手术方法进行治疗。结果:分别行液腹腔分流术16例,钻孔引流术6例,囟门引流术3例,穿刺术4例。25例完全康复,2例放弃治疗。结论:指征的操作取决于临床疾病的积液量和患者的体征和症状,而方法则由性质(积液成分)决定。且蛋白质含量高或随血而行外引流或经囟门吸入;反之,应行液腹腔分流术。
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引用次数: 0
STUDY ON THE ASSOCIATION BETWEEN ACE GENE POLYMORPHISMS WITH ESSENTIAL HYPERTENSION AND INSULIN RESISTANCE ace基因多态性与原发性高血压和胰岛素抵抗的关系研究
Pub Date : 2000-07-15 DOI: 10.3760/CMA.J.ISSN.1673-4904.2000.07.009
Y. Zhan, W. Qian, Hai-yan Wang
Objective:To explore the association of ACE gene polymorphisms with essential hypertension and insulin resistance in Chinese population.Mothod:A population-base case-control study was carried out.Possible factors related to essential hypertension were inquired in 112 essential hypertensive patients and the same amount of sex age-matched healthy control subjects.Their fasting blood sugar,fasting blood insulin were measured.ACE gene polymorphisms were measured by using PCR method.Result:The genotype composition of ACE(I/D) polymorphisms had significant difference between the case group and the control group.Genotype DD in the case group was higher than in the control group,espically for males case group.Compare with non-obesity subjects whose ACE genotype is DD,non-obesity subjects with genotype Ⅱ,especially for males,had a higher ISI value.Conclusion:The results suggest that genetic varitaion in the ACE gene may be associated with essential hypertension and insulin resistance in Chinese population.The genotype DD of ACE gene may be an independent predictor of essential hypertension,espically for men;and it could be a genetic linkage of essential hypertension.The non-obosity subjects with genotype Ⅱ of ACE gene,males in particular,are liable to insulin resistance.
目的:探讨ACE基因多态性与中国人群原发性高血压和胰岛素抵抗的关系。方法:采用人群为基础的病例对照研究。对112例原发性高血压患者和同等数量的性别、年龄匹配的健康对照者进行高血压相关因素调查。测量了他们的空腹血糖和空腹胰岛素。采用PCR法检测ACE基因多态性。结果:病例组与对照组ACE(I/D)多态性基因型组成差异有统计学意义。病例组DD基因型高于对照组,尤其是男性病例组。与ACE基因型为DD的非肥胖受试者相比,基因型为Ⅱ的非肥胖受试者,尤其是男性的ISI值更高。结论:ACE基因的遗传变异可能与中国人群原发性高血压和胰岛素抵抗有关。ACE基因的DD基因型可能是原发性高血压的独立预测因子,特别是对于男性,它可能是原发性高血压的遗传连锁。具有ACE基因Ⅱ型的非肥胖受试者,尤其是男性,易发生胰岛素抵抗。
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引用次数: 0
期刊
中国医师进修杂志
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