Г. А. Герасимов, И. Парванта, Lilia Turcan, G. Gerasimov
Йодирование соли в странах региона Европы и Центральной Азии (ЕЦАР) имеет долгую историю. Стратегии всеобщего йодирования соли (ВЙС) были повторно введены в странах ЕЦАР в середине 1990-х гг. и получили мощный импульс в течение десятилетия 2000–2009 гг.: к концу 2009 г. доступ населения в ЕЦАР к адекватно йодированной соли увеличился до 55%. Это было качественным скачком по сравнению с предыдущим десятилетием, но все еще ниже целевого показателя в 90%. Целью этого обзора было задокументировать достижения и проблемы ВЙС в 18 странах ЕЦАР за десятилетие 2010–2020 гг. и разработать рекомендации по устойчивому поддержанию ВЙС. Обзор проводился на основе анализа информации, полученной из различных источников, включая офисы ЮНИСЕФ и национальных координаторов глобальной сети по йоду (ГСЙ), а также общедоступных онлайн-ресурсов и публикаций. Исходя из имеющейся информации, страны ЕЦАР делятся на 3 группы. Группа 1. Йодный дефицит устойчиво устранен: 11 стран (Армения, Азербайджан, Босния и Герцеговина, Косово, Северная Македония, Черногория, Сербия, Туркменистан, Казахстан, Кыргызстан и Грузия) успешно сохранили достигнутый ранее адекватный йодный статус. Эта группа стран должна сосредоточиться на поддержании ВЙС, обеспечить включение цели ВЙС по использованию йодированной соли в домашних хозяйствах и пищевой и хлебопекарной промышленности в соответствующие национальные программы. Группа 2. Йодный дефицит устранен, но есть риск отката назад: 3 страны (Албания, Молдова и Кыргызстан) сохранили адекватный йодный статус населения, но потребление адекватно йодированной соли в домохозяйствах остается низким, а использование йодированной соли в промышленно обработанных пищевых продуктах (ПОПП) — неоднородным, тогда как слабая система мониторинга надзора ставит под угрозу устойчивость ВЙС. Этим странам даны рекомендации по обеспечению строгого мониторинга и соблюдения национальных стандартов йодированной соли для обеспечения постоянного и высокого (>90%) использования йодированной соли на уровне домашних хозяйств, а также при производстве основных солесодержащих ПОПП (в основном хлеба). Группа 3. Устранение йодного дефицита требует дополнительных усилий: в 4 странах (Россия, Таджикистан, Украина и Узбекистан) население в целом и наиболее уязвимые группы в частности сохраняют неадекватный йодный статус. Этой группе стран необходимо усилить внедрение ВЙС путем более тесного взаимодействия с производителями соли и частным сектором и выявления ресурсов для улучшения мониторинга. Принятие законодательства по ВЙС имеет первостепенное значение для достижения высокого охвата йодированной солью и оптимального йодного статуса населения в России и Украине. Материалы настоящего обзора подтверждают, что стратегия ВЙС успешно поддерживается в большинстве стран ЕЦАР. Опыт, накопленный в этом регионе, дополняет растущее количество свидетельств того, что ВЙС является эффективной стратегией снижения йодной недостаточности у населения, и поддерживает точку зрения о том, что глоба
{"title":"Progress in Iodine Deficiency Disorders (IDD) Control and Elimination in Europe and Central Asia Region (ECAR) in 2010–2020","authors":"Г. А. Герасимов, И. Парванта, Lilia Turcan, G. Gerasimov","doi":"10.14341/ket12713","DOIUrl":"https://doi.org/10.14341/ket12713","url":null,"abstract":"Йодирование соли в странах региона Европы и Центральной Азии (ЕЦАР) имеет долгую историю. Стратегии всеобщего йодирования соли (ВЙС) были повторно введены в странах ЕЦАР в середине 1990-х гг. и получили мощный импульс в течение десятилетия 2000–2009 гг.: к концу 2009 г. доступ населения в ЕЦАР к адекватно йодированной соли увеличился до 55%. Это было качественным скачком по сравнению с предыдущим десятилетием, но все еще ниже целевого показателя в 90%. Целью этого обзора было задокументировать достижения и проблемы ВЙС в 18 странах ЕЦАР за десятилетие 2010–2020 гг. и разработать рекомендации по устойчивому поддержанию ВЙС. Обзор проводился на основе анализа информации, полученной из различных источников, включая офисы ЮНИСЕФ и национальных координаторов глобальной сети по йоду (ГСЙ), а также общедоступных онлайн-ресурсов и публикаций. Исходя из имеющейся информации, страны ЕЦАР делятся на 3 группы. Группа 1. Йодный дефицит устойчиво устранен: 11 стран (Армения, Азербайджан, Босния и Герцеговина, Косово, Северная Македония, Черногория, Сербия, Туркменистан, Казахстан, Кыргызстан и Грузия) успешно сохранили достигнутый ранее адекватный йодный статус. Эта группа стран должна сосредоточиться на поддержании ВЙС, обеспечить включение цели ВЙС по использованию йодированной соли в домашних хозяйствах и пищевой и хлебопекарной промышленности в соответствующие национальные программы. Группа 2. Йодный дефицит устранен, но есть риск отката назад: 3 страны (Албания, Молдова и Кыргызстан) сохранили адекватный йодный статус населения, но потребление адекватно йодированной соли в домохозяйствах остается низким, а использование йодированной соли в промышленно обработанных пищевых продуктах (ПОПП) — неоднородным, тогда как слабая система мониторинга надзора ставит под угрозу устойчивость ВЙС. Этим странам даны рекомендации по обеспечению строгого мониторинга и соблюдения национальных стандартов йодированной соли для обеспечения постоянного и высокого (>90%) использования йодированной соли на уровне домашних хозяйств, а также при производстве основных солесодержащих ПОПП (в основном хлеба). Группа 3. Устранение йодного дефицита требует дополнительных усилий: в 4 странах (Россия, Таджикистан, Украина и Узбекистан) население в целом и наиболее уязвимые группы в частности сохраняют неадекватный йодный статус. Этой группе стран необходимо усилить внедрение ВЙС путем более тесного взаимодействия с производителями соли и частным сектором и выявления ресурсов для улучшения мониторинга. Принятие законодательства по ВЙС имеет первостепенное значение для достижения высокого охвата йодированной солью и оптимального йодного статуса населения в России и Украине. Материалы настоящего обзора подтверждают, что стратегия ВЙС успешно поддерживается в большинстве стран ЕЦАР. Опыт, накопленный в этом регионе, дополняет растущее количество свидетельств того, что ВЙС является эффективной стратегией снижения йодной недостаточности у населения, и поддерживает точку зрения о том, что глоба","PeriodicalId":10284,"journal":{"name":"Clinical and experimental thyroidology","volume":"130 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89200261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Г. Сарибекян, Д. А. Петренко, Д.А. Трухина, А. Г. Кузьмин, Л. К. Дзеранова, Л. В. Никанкина, Г. С. Колесникова, Anna G. Saribekian, D. Petrenko, D. Trukhina, A. Kuzmin, Dzeranova, L. V. Nikankina, Galina S. Kolesnikova
Thyroid stimulating hormone (TSH) is one of the key indicators in the diagnosis of the thyroid gland functional disorders. Minor changes in TSH concentration make it possible to suspect thyroid dysfunction even before clinical manifestations, which increases the value of correct and timely measurement of it. In the clinical practice, an endocrinologist often encounter the well-known phenomenon of macroprolactinemia; a much less common phenomenon is macrotyrotropinemia (macro-TSH). The presence of macro-TSH complexes can be suspected when the serum detects atypically high TSH values with reference values of FT4 without any signs of hypothyroidism. Since the phenomenon is based on an autoimmune mechanism, macro-TSH can often be detected in patients with autoimmune thyroiditis (AIT). This article presents clinical cases of patients with a combination of the macro-TSH phenomenon and primary hypothyroidism due to AIT.
{"title":"Macro-TSH in patients with primary hypothyroidism due to autoimmune thyroiditis","authors":"Г. Сарибекян, Д. А. Петренко, Д.А. Трухина, А. Г. Кузьмин, Л. К. Дзеранова, Л. В. Никанкина, Г. С. Колесникова, Anna G. Saribekian, D. Petrenko, D. Trukhina, A. Kuzmin, Dzeranova, L. V. Nikankina, Galina S. Kolesnikova","doi":"10.14341/ket12710","DOIUrl":"https://doi.org/10.14341/ket12710","url":null,"abstract":"Thyroid stimulating hormone (TSH) is one of the key indicators in the diagnosis of the thyroid gland functional disorders. Minor changes in TSH concentration make it possible to suspect thyroid dysfunction even before clinical manifestations, which increases the value of correct and timely measurement of it. In the clinical practice, an endocrinologist often encounter the well-known phenomenon of macroprolactinemia; a much less common phenomenon is macrotyrotropinemia (macro-TSH). The presence of macro-TSH complexes can be suspected when the serum detects atypically high TSH values with reference values of FT4 without any signs of hypothyroidism. Since the phenomenon is based on an autoimmune mechanism, macro-TSH can often be detected in patients with autoimmune thyroiditis (AIT). This article presents clinical cases of patients with a combination of the macro-TSH phenomenon and primary hypothyroidism due to AIT.","PeriodicalId":10284,"journal":{"name":"Clinical and experimental thyroidology","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83237767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
July 14, 2021 marks the 220th anniversary of an outstanding scientist and physician — Johann Peter Müller. It is thanks to his works that we know what the «endocrine gland» is, understand the taxonomy of the animal world and the essence of ontogenesis. Professor, researcher, wonderful teacher, director of the anatomical and physiological museum of the University of Berlin — he succeeded in any role in life. Mueller’s discoveries were recognized during his lifetime, textbooks were published under his leadership, and scientific articles were published. The value of the professor’s work is high to this day, which once again proves the colossal contribution of Johann Müller in the formation of world science.
{"title":"By an anniversary of the birth of Johann Peter Müller — 220 years","authors":"U. V. Buyvalenko, A. R. Levshina","doi":"10.14341/ket12567","DOIUrl":"https://doi.org/10.14341/ket12567","url":null,"abstract":"July 14, 2021 marks the 220th anniversary of an outstanding scientist and physician — Johann Peter Müller. It is thanks to his works that we know what the «endocrine gland» is, understand the taxonomy of the animal world and the essence of ontogenesis. Professor, researcher, wonderful teacher, director of the anatomical and physiological museum of the University of Berlin — he succeeded in any role in life. Mueller’s discoveries were recognized during his lifetime, textbooks were published under his leadership, and scientific articles were published. The value of the professor’s work is high to this day, which once again proves the colossal contribution of Johann Müller in the formation of world science.","PeriodicalId":10284,"journal":{"name":"Clinical and experimental thyroidology","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88342054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"From physics to medicine, fundamentalist Leonidas D. Marinelli","authors":"D. Yudakov, S. P. Bondarenko, A. Trukhin","doi":"10.14341/ket12547","DOIUrl":"https://doi.org/10.14341/ket12547","url":null,"abstract":"","PeriodicalId":10284,"journal":{"name":"Clinical and experimental thyroidology","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84030997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. A. Matsueva, A. Dalmatova, T. V. Andreychenko, E. Grineva
Treatment of thyrotoxicosis caused by Graves’ disease or multinodular toxic goiter, is not difficult, in most cases, since the prescription of thionamides allows to normalize the level of thyroid hormones quickly and safety. But in a number of cases this therapy might be associated with serious side effects (agranulocytosis, toxic hepatitis, cholestasis), severe allergic reactions and also individual intolerance on thionamides. In such cases lithium carbonate is used, especially in severe thyrotoxic syndrome. It is known, that lithium can accumulate in the thyroid gland at a concentration 3–4 times higher than in the plasma. Perhaps, lithium uses Na+/I- ions. It can inhibit the synthesis and secretion thyroid hormones of thyroid gland. The article presents the cases reported the use of lithium carbonate in thyrotoxicosis treatment before thyroidectomy. Administering low doses of carbonate lithium (900 mg/ per day) renders significant decrease or normalization of thyroid hormones concentration within 7–14 days, thus it let perform thyroidectomy on the patients. No side effects have been identified with such a short course of lithium carbonate treatment.
{"title":"Thyrotoxicosis treatment with lithium corbanate. Cases reported","authors":"I. A. Matsueva, A. Dalmatova, T. V. Andreychenko, E. Grineva","doi":"10.14341/ket12709","DOIUrl":"https://doi.org/10.14341/ket12709","url":null,"abstract":"Treatment of thyrotoxicosis caused by Graves’ disease or multinodular toxic goiter, is not difficult, in most cases, since the prescription of thionamides allows to normalize the level of thyroid hormones quickly and safety. But in a number of cases this therapy might be associated with serious side effects (agranulocytosis, toxic hepatitis, cholestasis), severe allergic reactions and also individual intolerance on thionamides. In such cases lithium carbonate is used, especially in severe thyrotoxic syndrome. It is known, that lithium can accumulate in the thyroid gland at a concentration 3–4 times higher than in the plasma. Perhaps, lithium uses Na+/I- ions. It can inhibit the synthesis and secretion thyroid hormones of thyroid gland. The article presents the cases reported the use of lithium carbonate in thyrotoxicosis treatment before thyroidectomy. Administering low doses of carbonate lithium (900 mg/ per day) renders significant decrease or normalization of thyroid hormones concentration within 7–14 days, thus it let perform thyroidectomy on the patients. No side effects have been identified with such a short course of lithium carbonate treatment.","PeriodicalId":10284,"journal":{"name":"Clinical and experimental thyroidology","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82283893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
А. Петеркова, О. Б. Безлепкина, В. Нагаева, Т. Ю. Ширяева, О. А. Чикулаева, Т. А. Вадина, Е. В. Шрёдер, Таранушенко, Елена Ефимовна Петряйкина, Олег Артурович Малиевский, А. В. Кияев, И. Б. Кострова, Е. Б. Башнина, Евгения Геннадьевна Михайлова, Гирш, Елена Борисовна Храмова, И. Л. Алимова, Любовь Николаевна Самсонова, Н. В. Болотова, Ф. Войно-Ясенецкого, Красноярск, Россия, Москва И. Пирогова, Россия Уфа, М. Н. Кураева, Россия Санкт-Петербург, Самара им. Н. Н. Ивановой, Россия Сургут, V. A. Peterkova, Olga B. Bezlepkina, E. V. Nagaeva, T. Y. Shiryaeva, Оlga А. Chikulaeva, Vadina, Ekaterina V. Shreder, Tatiana E. Taranushenko, Elena E. Petryaykina, O. Malievskiy, Kiyaev, Irina B. Kostrova, Elena B. Bashnina, Evgeniya G. Mikhailova, Yana V. Girsh, Elena B. Khramova, Alimova, Lubov Samsonova, N. V. Bolotova
The thyroiditis in children are urgent problem of pediatric endocrinology due to the widespread occurrence and characterized by clinical and pathogenetic heterogeneity. The developed clinical guidelines are the main working tool of the practitioner. They briefly and structurally present the main information about the epidemiology and modern classification of thyroiditis, methods of their diagnosis and treatment based on the principles of evidence-based medicine.
{"title":"Clinical guidelines «Thyroiditis in children»","authors":"А. Петеркова, О. Б. Безлепкина, В. Нагаева, Т. Ю. Ширяева, О. А. Чикулаева, Т. А. Вадина, Е. В. Шрёдер, Таранушенко, Елена Ефимовна Петряйкина, Олег Артурович Малиевский, А. В. Кияев, И. Б. Кострова, Е. Б. Башнина, Евгения Геннадьевна Михайлова, Гирш, Елена Борисовна Храмова, И. Л. Алимова, Любовь Николаевна Самсонова, Н. В. Болотова, Ф. Войно-Ясенецкого, Красноярск, Россия, Москва И. Пирогова, Россия Уфа, М. Н. Кураева, Россия Санкт-Петербург, Самара им. Н. Н. Ивановой, Россия Сургут, V. A. Peterkova, Olga B. Bezlepkina, E. V. Nagaeva, T. Y. Shiryaeva, Оlga А. Chikulaeva, Vadina, Ekaterina V. Shreder, Tatiana E. Taranushenko, Elena E. Petryaykina, O. Malievskiy, Kiyaev, Irina B. Kostrova, Elena B. Bashnina, Evgeniya G. Mikhailova, Yana V. Girsh, Elena B. Khramova, Alimova, Lubov Samsonova, N. V. Bolotova","doi":"10.14341/ket12711","DOIUrl":"https://doi.org/10.14341/ket12711","url":null,"abstract":"The thyroiditis in children are urgent problem of pediatric endocrinology due to the widespread occurrence and characterized by clinical and pathogenetic heterogeneity. The developed clinical guidelines are the main working tool of the practitioner. They briefly and structurally present the main information about the epidemiology and modern classification of thyroiditis, methods of their diagnosis and treatment based on the principles of evidence-based medicine.","PeriodicalId":10284,"journal":{"name":"Clinical and experimental thyroidology","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74391278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
August 25, 2021 marks the 180th anniversary of the birth of the renowned physician Emil Theodor Kocher. He was a man whose talent has manifested itself in various fields of medicine. Nowadays it is impossible to imagine a doctor who does not know the name of Kocher, because he is the author of many surgical methods and techniques that are still valid, despite advances in modern medicine. Furthermore, some of the instruments designed by Kocher are still used in surgery. In addition to the biography of Kocher, this article considers information about his work in the field of thyroidology, for which he received the Nobel Prize in 1909. Kocher has performed more than 5,000 thyroidectomies during his career. Thanks to the technique he developed, the mortality rate of that surgery decreased at least fortyfold. In those days there were not researches on functions of the thyroid gland, but Kocher noticed that total thyroidectomy leads to serious consequences. Therefore he refused to do such surgeries without invariable indications.
{"title":"On the 180th anniversary of Emil Theodor Kocher, a Swiss thyroid surgeon","authors":"М. Демина, Andrey А. Tulsky, Elena M. Demina","doi":"10.14341/ket12579","DOIUrl":"https://doi.org/10.14341/ket12579","url":null,"abstract":"August 25, 2021 marks the 180th anniversary of the birth of the renowned physician Emil Theodor Kocher. He was a man whose talent has manifested itself in various fields of medicine. Nowadays it is impossible to imagine a doctor who does not know the name of Kocher, because he is the author of many surgical methods and techniques that are still valid, despite advances in modern medicine. Furthermore, some of the instruments designed by Kocher are still used in surgery. In addition to the biography of Kocher, this article considers information about his work in the field of thyroidology, for which he received the Nobel Prize in 1909. Kocher has performed more than 5,000 thyroidectomies during his career. Thanks to the technique he developed, the mortality rate of that surgery decreased at least fortyfold. In those days there were not researches on functions of the thyroid gland, but Kocher noticed that total thyroidectomy leads to serious consequences. Therefore he refused to do such surgeries without invariable indications.","PeriodicalId":10284,"journal":{"name":"Clinical and experimental thyroidology","volume":"7 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91504849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Robert James Graves is an eminent medical practitioner who has made significant contributions to this field. The main path of the scientist began by no means with medical practice, but with extensive travels that prompted him to start and fruitfully carry out scientific activity in the future. The scientific activity carried out by Robert James Graves throughout his life formed special preconditions for the development of medical education and entire fields of medicine. The practice of students, according to his teaching model, was not typical, but many experts in this field spoke about it quite positively, for example, such as T.J. McKenn and Armand Trousseau. He made history 180 years ago by discovering an autoimmune disease, which causes hyperthyroidism, he was known as a physician whose contribution covered the entire field of endocrinology, cardiology, infectious diseases and neurology.
{"title":"To the 225th Anniversary of the Birth of Robert James Graves","authors":"A. L. Kurchakov, I. A. Likhova","doi":"10.14341/ket12557","DOIUrl":"https://doi.org/10.14341/ket12557","url":null,"abstract":"Robert James Graves is an eminent medical practitioner who has made significant contributions to this field. The main path of the scientist began by no means with medical practice, but with extensive travels that prompted him to start and fruitfully carry out scientific activity in the future. The scientific activity carried out by Robert James Graves throughout his life formed special preconditions for the development of medical education and entire fields of medicine. The practice of students, according to his teaching model, was not typical, but many experts in this field spoke about it quite positively, for example, such as T.J. McKenn and Armand Trousseau. He made history 180 years ago by discovering an autoimmune disease, which causes hyperthyroidism, he was known as a physician whose contribution covered the entire field of endocrinology, cardiology, infectious diseases and neurology.","PeriodicalId":10284,"journal":{"name":"Clinical and experimental thyroidology","volume":"81 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85544799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Shreder, T. Shiryaeva, E. Nagaeva, O. Bezlepkina
Congenital hypothyroidism is an actual clinical problem in pediatric practice. Previous clinical guidelines were published in 2014. The presented clinical recommendations are based on articles published from January 2013 to early 2020. The consensus guidelines include such sections as results of neonatal screening, diagnostics and criteria for treatment, lifelong follow-up, genetics of congenital hypothyroidism, family genetic counselling. The key points of new congenital hypothyroidism guidelines were commented by pediatric endocrinologists of Russians.
{"title":"Consensus guidelines of congenital hypothyroidism by the European Society for pediatric endocrinology and the European Society for Endocrinology: key points and comments","authors":"E. Shreder, T. Shiryaeva, E. Nagaeva, O. Bezlepkina","doi":"10.14341/ket12703","DOIUrl":"https://doi.org/10.14341/ket12703","url":null,"abstract":"Congenital hypothyroidism is an actual clinical problem in pediatric practice. Previous clinical guidelines were published in 2014. The presented clinical recommendations are based on articles published from January 2013 to early 2020. The consensus guidelines include such sections as results of neonatal screening, diagnostics and criteria for treatment, lifelong follow-up, genetics of congenital hypothyroidism, family genetic counselling. The key points of new congenital hypothyroidism guidelines were commented by pediatric endocrinologists of Russians.","PeriodicalId":10284,"journal":{"name":"Clinical and experimental thyroidology","volume":"129 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79587368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In May 2021, the 140th anniversary of his birth is celebrated by Japanese doctor Hakaru Hashimoto. Did not receive recognition during his lifetime, this amazing scientist discovered a new disease of the thyroid gland, which later became the eponym. For a long time, his name was forgotten, but the main work of his life was decades ahead of the development of science. Without it, the study of autoimmune pathologies, the incidence of which currently continues to increase, would be impossible. It was on patients with Hashimoto’s thyroiditis that a study was conducted for the first time, demonstrating not only the uniqueness of the pathogenesis of thyroiditis, but also the existence of autoimmune reactivity of the body as a whole.
{"title":"Life and Heritage of Hakaru Hashimoto","authors":"E. A. Lygina, V. V. Latyi","doi":"10.14341/ket12562","DOIUrl":"https://doi.org/10.14341/ket12562","url":null,"abstract":"In May 2021, the 140th anniversary of his birth is celebrated by Japanese doctor Hakaru Hashimoto. Did not receive recognition during his lifetime, this amazing scientist discovered a new disease of the thyroid gland, which later became the eponym. For a long time, his name was forgotten, but the main work of his life was decades ahead of the development of science. Without it, the study of autoimmune pathologies, the incidence of which currently continues to increase, would be impossible. It was on patients with Hashimoto’s thyroiditis that a study was conducted for the first time, demonstrating not only the uniqueness of the pathogenesis of thyroiditis, but also the existence of autoimmune reactivity of the body as a whole.","PeriodicalId":10284,"journal":{"name":"Clinical and experimental thyroidology","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75277193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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