首页 > 最新文献

CHRISMED Journal of Health and Research最新文献

英文 中文
Effect of antiretroviral therapy on lipid profile in newly diagnosed HIV-infected children of immune stage III and IV 抗逆转录病毒疗法对新诊断的免疫III期和IV期HIV感染儿童脂质状况的影响
Pub Date : 2022-07-01 DOI: 10.4103/cjhr.cjhr_93_21
Neelam Singh, Vijendra Garg, Rohitash Meena, Rambabu Sharma, S. Gothwal
Background: There are increasing concerns about the adverse effects of highly active antiretroviral therapy (HAART) on lipid profiles. Limited studies reported the adverse effects of HAART on lipid profiles from the Indian subcontinent. Methods: This observational study was conducted at a tertiary care hospital in North Western India. The objective of the study was to find out the adverse effects on lipid profiles after HAART initiation in newly diagnosed HIV-infected children of immune stage III and IV in the 18 months to 16 year age group. These 43 children were evaluated every 3 months for lipid profile for 1 year. Results: There was a nonsignificant increase in total lipid and phospholipid levels and a statistically significant increase in triglycerides (TGs), cholesterol, low-density lipoprotein (LDL), and very low-density lipoprotein (VLDL) levels after initiation of HAART therapy and a statistically significant decline in high-density lipoprotein (HDL) level after initiation of HAART therapy in immune phase III. The mean level of total lipid profile, phospholipids, cholesterol, HDL, LDL, VLDL, and TGs before starting of treatment was 474 mg/dl, 147 mg/dl, 126.8 mg/dl, 44.7 mg/dl, 94.3 mg/dl, 22.9 mg/dl, and110 mg/dl in immune stage IV, respectively. After starting treatment, the mean level of total lipid profile, phospholipids, cholesterol, HDL, LDL, VLDL, and TGs was 495.7 mg/dl, 164 mg/dl, 146.5 mg/dl, 38.9 mg/dl, 108.5 mg/dl, 28.9 mg/dl, and 127.3 mg/dl in immune stage IV, respectively. There was a statistically significant increase in total lipid, TG, phospholipid, cholesterol, LDL, and VLDL levels. There was a statistically significant decline in HDL level after initiation of HAART therapy in immune stage IV. Conclusions: We concluded that there was a significant alteration in lipid profile in HIV-infected children of immune stage III and IV with HAART.
背景:人们越来越担心高活性抗逆转录病毒疗法(HAART)对脂质的不良影响。有限的研究报告了HAART对印度次大陆脂质分布的不良影响。方法:这项观察性研究在印度西北部的一家三级护理医院进行。本研究的目的是了解18个月至16岁年龄组新诊断的免疫期III和IV的HIV感染儿童在开始HAART后对脂质状况的不良影响。这43名儿童每3个月进行一次为期1年的脂质状况评估。结果:总脂质和磷脂水平无显著增加,甘油三酯(TG)、胆固醇、低密度脂蛋白(LDL)、,以及HAART治疗开始后的极低密度脂蛋白(VLDL)水平,以及免疫期III中HAART治疗结束后的高密度脂蛋白水平的统计学显著下降。治疗开始前的总脂质、磷脂、胆固醇、HDL、LDL、VLDL和TG的平均水平为474mg/dl、147mg/dl、126.8mg/dl、44.7mg/dl、94.3mg/dl,免疫期IV分别为22.9mg/dl和110mg/dl。在开始治疗后,免疫阶段IV的总脂质、磷脂、胆固醇、HDL、LDL、VLDL和TG的平均水平分别为495.7mg/dl、164mg/dl、146.5mg/dl、38.9mg/dl、108.5mg/dl,28.9mg/dl和127.3mg/dl。总脂质、TG、磷脂、胆固醇、LDL和VLDL水平有统计学意义的增加。在免疫期IV开始接受HAART治疗后,HDL水平在统计学上显著下降。结论:我们得出的结论是,HAART免疫期III和IV的HIV感染儿童的脂质水平发生了显著变化。
{"title":"Effect of antiretroviral therapy on lipid profile in newly diagnosed HIV-infected children of immune stage III and IV","authors":"Neelam Singh, Vijendra Garg, Rohitash Meena, Rambabu Sharma, S. Gothwal","doi":"10.4103/cjhr.cjhr_93_21","DOIUrl":"https://doi.org/10.4103/cjhr.cjhr_93_21","url":null,"abstract":"Background: There are increasing concerns about the adverse effects of highly active antiretroviral therapy (HAART) on lipid profiles. Limited studies reported the adverse effects of HAART on lipid profiles from the Indian subcontinent. Methods: This observational study was conducted at a tertiary care hospital in North Western India. The objective of the study was to find out the adverse effects on lipid profiles after HAART initiation in newly diagnosed HIV-infected children of immune stage III and IV in the 18 months to 16 year age group. These 43 children were evaluated every 3 months for lipid profile for 1 year. Results: There was a nonsignificant increase in total lipid and phospholipid levels and a statistically significant increase in triglycerides (TGs), cholesterol, low-density lipoprotein (LDL), and very low-density lipoprotein (VLDL) levels after initiation of HAART therapy and a statistically significant decline in high-density lipoprotein (HDL) level after initiation of HAART therapy in immune phase III. The mean level of total lipid profile, phospholipids, cholesterol, HDL, LDL, VLDL, and TGs before starting of treatment was 474 mg/dl, 147 mg/dl, 126.8 mg/dl, 44.7 mg/dl, 94.3 mg/dl, 22.9 mg/dl, and110 mg/dl in immune stage IV, respectively. After starting treatment, the mean level of total lipid profile, phospholipids, cholesterol, HDL, LDL, VLDL, and TGs was 495.7 mg/dl, 164 mg/dl, 146.5 mg/dl, 38.9 mg/dl, 108.5 mg/dl, 28.9 mg/dl, and 127.3 mg/dl in immune stage IV, respectively. There was a statistically significant increase in total lipid, TG, phospholipid, cholesterol, LDL, and VLDL levels. There was a statistically significant decline in HDL level after initiation of HAART therapy in immune stage IV. Conclusions: We concluded that there was a significant alteration in lipid profile in HIV-infected children of immune stage III and IV with HAART.","PeriodicalId":10321,"journal":{"name":"CHRISMED Journal of Health and Research","volume":"9 1","pages":"159 - 163"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48991812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fosfomycin susceptibility among multidrug resistant and extended spectrum β-Lactamase producing uropathogenic Escherichia coli isolates at a tertiary care hospital of Western India 西印度一家三级医院多药耐药性和产β-内酰胺酶的尿路致病性大肠杆菌对磷霉素的敏感性
Pub Date : 2022-04-01 DOI: 10.4103/cjhr.cjhr_21_21
R. Jain, N. Pal, S. Hooja
Introduction: Urinary tract infections are mostly treated empirically with broad-spectrum antibiotics which have resulted in development of multi-drug resistant strains. Limited options of newer antibiotics have necessitated the reintroduction of some old antimicrobial agents such as fosfomycin. Aim: To evaluate the in-vitro activity of fosfomycin against uropathogenic E.coli. Method: A total of 145 E.coli isolates were identified by conventional microbiological procedures and antimicrobial susceptibility performed by Kirby-Bauer disk diffusion method. They were screened for extended spectrum β-lactamase (ESBL) production and screen positives were confirmed by phenotypic confirmatory test (CLSI). Results: Out of 145 isolates, 91 (62.76 %) were found in males and 54 (37.24%) from females. Majority of the isolates were detected in the age group of 21-30 years 48.96%. A very high susceptibility of 94.48% was observed with fosfomycin. Suceptibility to tigecycline and nitrofurantoin was 87.58 % and 77.24 % respectively. Multi-drug resistance was observed in 85.51% isolates and 45.51% were ESBL producers. Conclusion: Fosfomycin showed an excellent in vitro activity against MDR and ESBL producing E.coli, therefore it should be considered as a potential therapeutic alternative in the treatment of UTI.
引言:尿路感染大多采用广谱抗生素治疗,这导致了多药耐药菌株的发展。新抗生素的选择有限,必须重新引入一些旧的抗菌剂,如磷霉素。目的:评价磷霉素对尿路致病性大肠杆菌的体外抗菌活性。对其进行超广谱β-内酰胺酶(ESBL)生产筛选,并通过表型验证试验(CLSI)确认筛选阳性。结果:145株分离株中,男性91株(62.76%),女性54株(37.24%)。大多数分离株在21-30岁年龄组中检出,检出率为48.96%。磷霉素的敏感性很高,达94.48%。对替加环素和呋喃妥因的敏感性分别为87.58%和77.24%。85.51%的分离株和45.51%的产ESBL菌株对多种药物产生耐药性。结论:磷霉素对耐多药耐药和产ESBL大肠杆菌具有良好的体外活性,是治疗尿路感染的一种潜在选择。
{"title":"Fosfomycin susceptibility among multidrug resistant and extended spectrum β-Lactamase producing uropathogenic Escherichia coli isolates at a tertiary care hospital of Western India","authors":"R. Jain, N. Pal, S. Hooja","doi":"10.4103/cjhr.cjhr_21_21","DOIUrl":"https://doi.org/10.4103/cjhr.cjhr_21_21","url":null,"abstract":"Introduction: Urinary tract infections are mostly treated empirically with broad-spectrum antibiotics which have resulted in development of multi-drug resistant strains. Limited options of newer antibiotics have necessitated the reintroduction of some old antimicrobial agents such as fosfomycin. Aim: To evaluate the in-vitro activity of fosfomycin against uropathogenic E.coli. Method: A total of 145 E.coli isolates were identified by conventional microbiological procedures and antimicrobial susceptibility performed by Kirby-Bauer disk diffusion method. They were screened for extended spectrum β-lactamase (ESBL) production and screen positives were confirmed by phenotypic confirmatory test (CLSI). Results: Out of 145 isolates, 91 (62.76 %) were found in males and 54 (37.24%) from females. Majority of the isolates were detected in the age group of 21-30 years 48.96%. A very high susceptibility of 94.48% was observed with fosfomycin. Suceptibility to tigecycline and nitrofurantoin was 87.58 % and 77.24 % respectively. Multi-drug resistance was observed in 85.51% isolates and 45.51% were ESBL producers. Conclusion: Fosfomycin showed an excellent in vitro activity against MDR and ESBL producing E.coli, therefore it should be considered as a potential therapeutic alternative in the treatment of UTI.","PeriodicalId":10321,"journal":{"name":"CHRISMED Journal of Health and Research","volume":"9 1","pages":"125 - 129"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46930308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SARS-CoV-2-related multisystem inflammatory syndrome in children and adolescents 儿童和青少年sars - cov -2相关多系统炎症综合征
Pub Date : 2022-04-01 DOI: 10.4103/cjhr.cjhr_71_21
Arpita Gupta
{"title":"SARS-CoV-2-related multisystem inflammatory syndrome in children and adolescents","authors":"Arpita Gupta","doi":"10.4103/cjhr.cjhr_71_21","DOIUrl":"https://doi.org/10.4103/cjhr.cjhr_71_21","url":null,"abstract":"","PeriodicalId":10321,"journal":{"name":"CHRISMED Journal of Health and Research","volume":"9 1","pages":"105 - 106"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43726499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Leishmanial lymphadenopathy in a native patient from the nonendemic region of Himachal Pradesh, India 印度喜马偕尔邦非流行区一名本地患者的利什曼原虫淋巴结病
Pub Date : 2022-04-01 DOI: 10.4103/cjhr.cjhr_87_21
R. Raina, Shubham Sharma, N. Verma, Meghavath Bai, Ritika Kashyap, S. Raina
A case of leishmanial lymphadenopathy in an immunocompetent native from a nonendemic area of the Ravi River valley area (altitude 996 m above the mean sea level) of Chamba, Himachal Pradesh, India, is reported. Diagnosis of visceral leishmaniasis by demonstration of Leishman–Donovan bodies in lymph nodes by fine-needle aspiration cytology has been rarely reported.
报道了一例来自印度喜马偕尔邦查巴拉维河谷地区(海拔平均海平面以上996米)非流行区的免疫活性本地人的利什曼原虫淋巴结病病例。通过细针抽吸细胞学检查淋巴结中的利什曼氏体来诊断内脏利什曼病的报道很少。
{"title":"Leishmanial lymphadenopathy in a native patient from the nonendemic region of Himachal Pradesh, India","authors":"R. Raina, Shubham Sharma, N. Verma, Meghavath Bai, Ritika Kashyap, S. Raina","doi":"10.4103/cjhr.cjhr_87_21","DOIUrl":"https://doi.org/10.4103/cjhr.cjhr_87_21","url":null,"abstract":"A case of leishmanial lymphadenopathy in an immunocompetent native from a nonendemic area of the Ravi River valley area (altitude 996 m above the mean sea level) of Chamba, Himachal Pradesh, India, is reported. Diagnosis of visceral leishmaniasis by demonstration of Leishman–Donovan bodies in lymph nodes by fine-needle aspiration cytology has been rarely reported.","PeriodicalId":10321,"journal":{"name":"CHRISMED Journal of Health and Research","volume":"9 1","pages":"140 - 142"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42969017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A randomized controlled trial of lidocaine versus ropivacaine for pain relief after episiotomy 利多卡因与罗哌卡因缓解会阴切开术后疼痛的随机对照试验
Pub Date : 2022-04-01 DOI: 10.4103/cjhr.cjhr_88_20
Asis Adhikary, Papiya Biswas, T. Mondal, S. Bhattacharyya
Introduction: Episiotomy is the most common surgical procedure for parturient. Analgesia after episiotomy has received less attention, though the postepisiotomy pain may hamper the day-to-day activities such as sitting, sleeping, urinating, and walking of the parturient. It is desirable to reduce the postepisiotomy pain as early as possible. Therefore, we planned to carry out a randomized controlled trial to compare the safety and efficacy of lidocaine versus ropivacaine perineal infiltration for pain relief after episiotomy. Materials and Methods: The prospective randomized controlled trial was conducted in the Department of Obstetrics and Gynaecology of R. G. Kar Medical College and Hospital, Kolkata. One hundred women were enrolled and randomized into the two groups: Lidocaine infiltration group and ropivacaine infiltration group. Primary objective was to evaluate the efficacy of postepisiotomy pain control by the visual analog scale (VAS) score at 24 h after the episiotomy. Secondary objectives were to evaluate the efficacy of postepisiotomy pain control by VAS score during suturing, at 2 h and 48 h or any adverse effects and maternal satisfaction at 48 h. Results: The postepisiotomy pain relief at 2 h and 24 h was significantly lower in ropivacaine in comparison to lidocaine infiltration. Mean VAS Score 24 h after suturing in lidocaine group was 6.38, and in ropivacaine group, it was 5.64. Maternal pain perception at the time of suturing and at 48 h was also less in ropivacaine than in lidocaine infiltration. Mothers were more satisfied with ropivacaine drug. Conclusion: The present study showed that there was definite improvement of postepisiotomy pain relief at 2 h and 24 h in ropivacaine local infiltration of the episiotomy wound in comparison to lidocaine infiltration and mothers were more satisfied with ropivacaine use.
简介:会阴切开术是产妇最常见的外科手术。尽管会阴切开术后的疼痛可能会阻碍产妇的日常活动,如坐、睡、尿和走路,但会阴切开术的镇痛作用却很少受到关注。希望尽早减轻会阴切开术后的疼痛。因此,我们计划进行一项随机对照试验,比较利多卡因和罗哌卡因会阴浸润缓解会阴切开术后疼痛的安全性和有效性。材料和方法:前瞻性随机对照试验在加尔各答R.G.Kar医学院妇产科进行。将100名女性随机分为两组:利多卡因渗透组和罗哌卡因渗透组。主要目的是通过在会阴切开术后24小时的视觉模拟量表(VAS)评分来评估会阴切开后疼痛控制的疗效。次要目的是通过缝合过程中2小时和48小时的VAS评分或任何不良反应和48小时产妇满意度来评估会阴切开术后疼痛控制的疗效。结果:与利多卡因浸润相比,罗哌卡因在2小时和24小时的会阴切开后疼痛缓解显著较低。利多卡因组缝合后24小时的平均VAS评分为6.38,罗哌卡因组为5.64。在缝合时和48小时时,罗哌卡因的母体疼痛感也低于利多卡因浸润。母亲们对罗哌卡因药物更满意。结论:本研究表明,与利多卡因浸润相比,罗哌卡因对会阴切开伤口的局部浸润在2小时和24小时的会阴切开后疼痛缓解有明显改善,母亲对罗哌卡因的使用更满意。
{"title":"A randomized controlled trial of lidocaine versus ropivacaine for pain relief after episiotomy","authors":"Asis Adhikary, Papiya Biswas, T. Mondal, S. Bhattacharyya","doi":"10.4103/cjhr.cjhr_88_20","DOIUrl":"https://doi.org/10.4103/cjhr.cjhr_88_20","url":null,"abstract":"Introduction: Episiotomy is the most common surgical procedure for parturient. Analgesia after episiotomy has received less attention, though the postepisiotomy pain may hamper the day-to-day activities such as sitting, sleeping, urinating, and walking of the parturient. It is desirable to reduce the postepisiotomy pain as early as possible. Therefore, we planned to carry out a randomized controlled trial to compare the safety and efficacy of lidocaine versus ropivacaine perineal infiltration for pain relief after episiotomy. Materials and Methods: The prospective randomized controlled trial was conducted in the Department of Obstetrics and Gynaecology of R. G. Kar Medical College and Hospital, Kolkata. One hundred women were enrolled and randomized into the two groups: Lidocaine infiltration group and ropivacaine infiltration group. Primary objective was to evaluate the efficacy of postepisiotomy pain control by the visual analog scale (VAS) score at 24 h after the episiotomy. Secondary objectives were to evaluate the efficacy of postepisiotomy pain control by VAS score during suturing, at 2 h and 48 h or any adverse effects and maternal satisfaction at 48 h. Results: The postepisiotomy pain relief at 2 h and 24 h was significantly lower in ropivacaine in comparison to lidocaine infiltration. Mean VAS Score 24 h after suturing in lidocaine group was 6.38, and in ropivacaine group, it was 5.64. Maternal pain perception at the time of suturing and at 48 h was also less in ropivacaine than in lidocaine infiltration. Mothers were more satisfied with ropivacaine drug. Conclusion: The present study showed that there was definite improvement of postepisiotomy pain relief at 2 h and 24 h in ropivacaine local infiltration of the episiotomy wound in comparison to lidocaine infiltration and mothers were more satisfied with ropivacaine use.","PeriodicalId":10321,"journal":{"name":"CHRISMED Journal of Health and Research","volume":"9 1","pages":"130 - 134"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46670170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Strengthening of health care and local production of medicines and other health technologies to improve access and affordability 加强医疗保健和药品及其他卫生技术的当地生产,以提高获取和负担能力
Pub Date : 2022-04-01 DOI: 10.4103/cjhr.cjhr_83_21
Abhijit V. Boratne, M. Murugan, Senkadhirdasan Dakshinamurthy
A lot of discussion happened regarding the required World Health Organization's support to strengthen local production of drugs in this pandemic. During the COVID-19 pandemic, the world has struggled for everything starting from the availability of masks, personal protective equipment's, medicines, equipment, ventilators, and even basic oxygen. All these needs have exposed the existing condition of our health-care system that has called for improving the infrastructure and workforce at the earliest. Health-care spending and its impact on economic performance are vital to be seen leading to an increase in gross domestic product and vice versa. A recent estimate states that our country which was told as world's pharmacy is now facing a shortage of vaccines doses. A recent estimate states that our country which was told as world's pharmacy is now facing a shortage of vaccines doses creating the necessary research and development to discover or develop innovative way of strengthening the local production of medicines. The Ministry of Health and Family Welfare in India has initiated several measures to ensure the quality of drugs available in India. Lower- and middle-income countries face macroeconomic vulnerabilities, high levels of poverty and are lagging behind the universal health coverage. Hence, necessary recommendations were arrived for these issues in this article.
关于世界卫生组织在这场疫情中加强当地药品生产所需的支持,人们进行了大量讨论。在新冠肺炎大流行期间,从口罩、个人防护设备、药品、设备、呼吸机,甚至基本氧气的供应,全世界都在为一切而奋斗。所有这些需求暴露了我们医疗保健系统的现有状况,要求尽早改善基础设施和劳动力。医疗保健支出及其对经济表现的影响至关重要,这将导致国内生产总值的增长,反之亦然。最近的一项估计表明,我们这个被称为世界药房的国家现在面临疫苗剂量短缺的问题。最近的一项估计表明,我们这个被称为世界药房的国家现在面临疫苗剂量短缺的问题,这就需要进行必要的研发,以发现或开发加强当地药品生产的创新方式。印度卫生和家庭福利部已采取若干措施,确保印度现有药品的质量。低收入和中等收入国家面临宏观经济脆弱性、高度贫困和落后于全民医疗保险。因此,本文针对这些问题提出了必要的建议。
{"title":"Strengthening of health care and local production of medicines and other health technologies to improve access and affordability","authors":"Abhijit V. Boratne, M. Murugan, Senkadhirdasan Dakshinamurthy","doi":"10.4103/cjhr.cjhr_83_21","DOIUrl":"https://doi.org/10.4103/cjhr.cjhr_83_21","url":null,"abstract":"A lot of discussion happened regarding the required World Health Organization's support to strengthen local production of drugs in this pandemic. During the COVID-19 pandemic, the world has struggled for everything starting from the availability of masks, personal protective equipment's, medicines, equipment, ventilators, and even basic oxygen. All these needs have exposed the existing condition of our health-care system that has called for improving the infrastructure and workforce at the earliest. Health-care spending and its impact on economic performance are vital to be seen leading to an increase in gross domestic product and vice versa. A recent estimate states that our country which was told as world's pharmacy is now facing a shortage of vaccines doses. A recent estimate states that our country which was told as world's pharmacy is now facing a shortage of vaccines doses creating the necessary research and development to discover or develop innovative way of strengthening the local production of medicines. The Ministry of Health and Family Welfare in India has initiated several measures to ensure the quality of drugs available in India. Lower- and middle-income countries face macroeconomic vulnerabilities, high levels of poverty and are lagging behind the universal health coverage. Hence, necessary recommendations were arrived for these issues in this article.","PeriodicalId":10321,"journal":{"name":"CHRISMED Journal of Health and Research","volume":"9 1","pages":"112 - 117"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49488385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Malaria and dengue coinfection 疟疾和登革热合并感染
Pub Date : 2022-04-01 DOI: 10.4103/cjhr.cjhr_62_21
Amandeep Kaur, Monika Sharma
Concurrent infection of malaria and dengue may be difficult to diagnose because of overlapping signs and symptoms. An 11-year-old boy presenting in the causality with blanching rash, respiratory distress, and hypotension was initially managed as dengue shock syndrome. Due to high-grade fever and hepatosplenomegaly, peripheral blood film for malarial parasite was sent, which came out to be positive for vivax malaria. This case report emphasizes the need to consider about the possibility of dengue–malaria coinfection in the endemic areas and highlights the challenges related to management among these patients.
疟疾和登革热同时感染可能很难诊断,因为症状和体征重叠。一名11岁男孩出现白灼皮疹、呼吸窘迫和低血压,最初被诊断为登革热休克综合征。由于高度发热和肝脾肿大,发送了疟疾寄生虫的外周血胶片,结果间日疟呈阳性。本病例报告强调需要考虑登革热-疟疾在流行地区合并感染的可能性,并强调了这些患者在管理方面的挑战。
{"title":"Malaria and dengue coinfection","authors":"Amandeep Kaur, Monika Sharma","doi":"10.4103/cjhr.cjhr_62_21","DOIUrl":"https://doi.org/10.4103/cjhr.cjhr_62_21","url":null,"abstract":"Concurrent infection of malaria and dengue may be difficult to diagnose because of overlapping signs and symptoms. An 11-year-old boy presenting in the causality with blanching rash, respiratory distress, and hypotension was initially managed as dengue shock syndrome. Due to high-grade fever and hepatosplenomegaly, peripheral blood film for malarial parasite was sent, which came out to be positive for vivax malaria. This case report emphasizes the need to consider about the possibility of dengue–malaria coinfection in the endemic areas and highlights the challenges related to management among these patients.","PeriodicalId":10321,"journal":{"name":"CHRISMED Journal of Health and Research","volume":"9 1","pages":"143 - 145"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47689321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lock to unlock: A multidimensional impact of COVID-19 in India 锁定解锁:新冠肺炎对印度的多层面影响
Pub Date : 2022-04-01 DOI: 10.4103/cjhr.cjhr_82_21
M. Mageshwari, Abhijit Vinodrao
The COVID-19 pandemic forced for first lockdown in India in March 2020. Resurgence of COVID-19 cases has forced many states in India to reintroduce the movement restrictions in March 2021. With four times increase in number of cases, many hospitals are swamped with patients, shortage of doctors and healthcare workers, shortage of personal protective equipment (PPEs), medications, and oxygen. The second wave led to out of pocket expenditures, hike in health care budget, burnouts among the health care workers (HCWs), migration, and hampered education system. The crisis was due to insufficient oxygen and beds, repeated changes in the treatment protocol and testing strategies, violence against HCWs and front line workers (FLWs), vaccination hesitancy to vaccination shortage, and increased morbidity to mortality. The quarantine and isolation of HCWs and FLWs become difficult due to the insufficient workforce. This formed as an opportunity leading to public–private partnership for patient care and successful vaccination. The pandemic brought the concept of advanced technologies and inventions such as use of Robotics, Apps such as Arogyasetu and CoWin, Ventilators, and O2 plants (O2 concentrator), and self-testing kits (COVISELF). Apart from the COVID appropriate behaviors, mass vaccination and newly approved treatments, the policymakers can stabilize the country with helping hand from industries, development of workforce, adequate production, and supply of medicines-vaccine and PPEs to rejuvenate the healthcare industry at the earliest.
新冠肺炎疫情迫使印度于2020年3月首次实施封锁。新冠肺炎病例的重新出现迫使印度许多邦在2021年3月重新实施行动限制。随着病例数量增加了四倍,许多医院挤满了病人,医生和医护人员短缺,个人防护设备、药物和氧气短缺。第二波疫情导致了自掏腰包的支出、医疗保健预算的增加、医护人员的流失、移民,并阻碍了教育系统。这场危机是由于氧气和床位不足、治疗方案和检测策略的反复变化、针对HCW和一线工作人员的暴力行为、疫苗接种对疫苗接种短缺的犹豫以及发病率上升到死亡率。由于劳动力不足,HCW和FLW的检疫和隔离变得困难。这为患者护理和成功接种疫苗提供了公私合作的机会。疫情带来了先进技术和发明的概念,如机器人、Arogyasetu和CoWin等应用程序、呼吸机和O2工厂(O2浓缩器)以及自检试剂盒(COVISELF)的使用。除了适当的新冠肺炎行为、大规模疫苗接种和新批准的治疗方法外,政策制定者还可以通过行业、劳动力发展、充足的生产以及药品、疫苗和个人防护用品的供应来稳定国家,以尽早振兴医疗行业。
{"title":"Lock to unlock: A multidimensional impact of COVID-19 in India","authors":"M. Mageshwari, Abhijit Vinodrao","doi":"10.4103/cjhr.cjhr_82_21","DOIUrl":"https://doi.org/10.4103/cjhr.cjhr_82_21","url":null,"abstract":"The COVID-19 pandemic forced for first lockdown in India in March 2020. Resurgence of COVID-19 cases has forced many states in India to reintroduce the movement restrictions in March 2021. With four times increase in number of cases, many hospitals are swamped with patients, shortage of doctors and healthcare workers, shortage of personal protective equipment (PPEs), medications, and oxygen. The second wave led to out of pocket expenditures, hike in health care budget, burnouts among the health care workers (HCWs), migration, and hampered education system. The crisis was due to insufficient oxygen and beds, repeated changes in the treatment protocol and testing strategies, violence against HCWs and front line workers (FLWs), vaccination hesitancy to vaccination shortage, and increased morbidity to mortality. The quarantine and isolation of HCWs and FLWs become difficult due to the insufficient workforce. This formed as an opportunity leading to public–private partnership for patient care and successful vaccination. The pandemic brought the concept of advanced technologies and inventions such as use of Robotics, Apps such as Arogyasetu and CoWin, Ventilators, and O2 plants (O2 concentrator), and self-testing kits (COVISELF). Apart from the COVID appropriate behaviors, mass vaccination and newly approved treatments, the policymakers can stabilize the country with helping hand from industries, development of workforce, adequate production, and supply of medicines-vaccine and PPEs to rejuvenate the healthcare industry at the earliest.","PeriodicalId":10321,"journal":{"name":"CHRISMED Journal of Health and Research","volume":"9 1","pages":"107 - 111"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49339231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Duties, responsibilities, and challenges of community health workers: Evidence from a health block of northern Indian province 社区卫生工作者的职责、责任和挑战:来自印度北部省份卫生区的证据
Pub Date : 2022-04-01 DOI: 10.4103/cjhr.cjhr_35_21
Ramesh Rattu, Manoj Kumar, K. Sekhri, Ankit Chaudhary
Introduction: Accredited Social Health Activist (ASHA) worker is a significant frontline health worker that acts as a link between community and health services and helps delivering quality health services to vulnerable section of the society. The present study was conducted with an objective to explore the duties and responsibilities of the ASHA worker along with obstacles faced by them while discharging their duties. Methods: It was a cross-sectional study including 150 ASHA workers of a health block in Himachal Pradesh. Data were collected using a semi-structured questionnaire consisting of six subsections dedicated to different dimensions related to ASHA workers. Results: Majority of ASHAs stated that their job had a positive effect on their social relationships, confidence as well as their physical and mental health. About two-thirds workers failed to fulfill targets due to many activities running simultaneously. About 43.3% felt mental stress during the job and 20.7% workers experienced harassment by hospital staff. About 40% stated that they had received unsatisfactory training. Toilet facility was available for only 59.3% workers and safe drinking water for 64.7% ASHAs. Only 4.7% of ASHAs were satisfied with their monthly income. Conclusion: While ASHAs are working with dedication in the field, still they are experiencing many problems associated with their personal life, community norms, terrain of the workplace, transportation, and organizational issues. The study recommends few amendments as ASHAs being an integral part of Indian health system must be given their due consideration so that the vision of universal health coverage and sustained development can be attained effectively.
简介:经认证的社会卫生活动家(ASHA)工作者是重要的一线卫生工作者,作为社区和卫生服务之间的联系,并帮助向社会弱势群体提供高质量的卫生服务。本研究的目的是探讨ASHA工作者的职责和责任,以及他们在履行职责时面临的障碍。方法:对喜马偕尔邦某卫生街区150名ASHA工作人员进行横断面研究。使用半结构化问卷收集数据,该问卷由六个小节组成,专门用于与ASHA员工相关的不同维度。结果:绝大多数asha表示,他们的工作对他们的社会关系、自信以及身心健康都有积极的影响。约有三分之二的员工未能完成目标,因为许多活动同时进行。约43.3%的工人在工作期间感到精神压力,20.7%的工人受到医院工作人员的骚扰。约40%的人表示,他们接受的培训并不令人满意。只有59.3%的工人有厕所设施,64.7%的asha有安全饮用水。只有4.7%的asha对他们的月收入感到满意。结论:虽然asha在这一领域兢兢业业,但他们仍然遇到许多与个人生活、社区规范、工作场所地形、交通和组织问题相关的问题。该研究建议很少修改,因为ASHAs是印度卫生系统的一个组成部分,必须给予应有的考虑,这样才能有效地实现全民健康覆盖和可持续发展的愿景。
{"title":"Duties, responsibilities, and challenges of community health workers: Evidence from a health block of northern Indian province","authors":"Ramesh Rattu, Manoj Kumar, K. Sekhri, Ankit Chaudhary","doi":"10.4103/cjhr.cjhr_35_21","DOIUrl":"https://doi.org/10.4103/cjhr.cjhr_35_21","url":null,"abstract":"Introduction: Accredited Social Health Activist (ASHA) worker is a significant frontline health worker that acts as a link between community and health services and helps delivering quality health services to vulnerable section of the society. The present study was conducted with an objective to explore the duties and responsibilities of the ASHA worker along with obstacles faced by them while discharging their duties. Methods: It was a cross-sectional study including 150 ASHA workers of a health block in Himachal Pradesh. Data were collected using a semi-structured questionnaire consisting of six subsections dedicated to different dimensions related to ASHA workers. Results: Majority of ASHAs stated that their job had a positive effect on their social relationships, confidence as well as their physical and mental health. About two-thirds workers failed to fulfill targets due to many activities running simultaneously. About 43.3% felt mental stress during the job and 20.7% workers experienced harassment by hospital staff. About 40% stated that they had received unsatisfactory training. Toilet facility was available for only 59.3% workers and safe drinking water for 64.7% ASHAs. Only 4.7% of ASHAs were satisfied with their monthly income. Conclusion: While ASHAs are working with dedication in the field, still they are experiencing many problems associated with their personal life, community norms, terrain of the workplace, transportation, and organizational issues. The study recommends few amendments as ASHAs being an integral part of Indian health system must be given their due consideration so that the vision of universal health coverage and sustained development can be attained effectively.","PeriodicalId":10321,"journal":{"name":"CHRISMED Journal of Health and Research","volume":"9 1","pages":"135 - 139"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47803836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Experiential teaching learning of humanities in health professions education 健康职业教育中的人文体验式教学
Pub Date : 2022-04-01 DOI: 10.4103/cjhr.cjhr_161_20
Anushi Mahajan, P. Bhagat, Sudhir Babu, A. Singhal, D. Badyal, R. Mahajan
Humanities are an integral part of health professions. However, with educational focus shifting gradually toward knowledge, information, evidence-based medicine, and technology, it has taken a back seat and become a part of the “hidden curriculum.” Humanities are hardly ever taught upfront to students of the health profession, let alone its assessment. With the need of its inclusion in health professional education now recognized and established through competency-based education, we need to be aware of the tools and strategies which can be used to teach and assess it. In this article, we share selected tools with relevant readily usable examples for teaching humanities to students of the health profession. Faculty may find it useful to plan sessions around related competencies. Incorporation of such experiential teaching and learning methods can help us achieve the transition from “high-tech” to “high touch” health professions education.
人文学科是卫生专业的一个组成部分。然而,随着教育的重点逐渐转向知识、信息、循证医学和技术,它已经退居次要地位,成为“隐藏课程”的一部分。人文学科几乎从来没有预先教授给卫生专业的学生,更不用说对其进行评估了。由于现在认识到并通过以能力为基础的教育确立了将其纳入卫生专业教育的必要性,我们需要了解可用于教授和评估它的工具和战略。在这篇文章中,我们分享了一些选择的工具和相关的现成的例子,用于向卫生专业的学生教授人文学科。教师可能会发现围绕相关能力计划课程是很有用的。结合这种体验式教学和学习方法,可以帮助我们实现从“高科技”到“高触感”的卫生专业教育的转变。
{"title":"Experiential teaching learning of humanities in health professions education","authors":"Anushi Mahajan, P. Bhagat, Sudhir Babu, A. Singhal, D. Badyal, R. Mahajan","doi":"10.4103/cjhr.cjhr_161_20","DOIUrl":"https://doi.org/10.4103/cjhr.cjhr_161_20","url":null,"abstract":"Humanities are an integral part of health professions. However, with educational focus shifting gradually toward knowledge, information, evidence-based medicine, and technology, it has taken a back seat and become a part of the “hidden curriculum.” Humanities are hardly ever taught upfront to students of the health profession, let alone its assessment. With the need of its inclusion in health professional education now recognized and established through competency-based education, we need to be aware of the tools and strategies which can be used to teach and assess it. In this article, we share selected tools with relevant readily usable examples for teaching humanities to students of the health profession. Faculty may find it useful to plan sessions around related competencies. Incorporation of such experiential teaching and learning methods can help us achieve the transition from “high-tech” to “high touch” health professions education.","PeriodicalId":10321,"journal":{"name":"CHRISMED Journal of Health and Research","volume":"9 1","pages":"118 - 124"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47612807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
CHRISMED Journal of Health and Research
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1