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Clinical and Experimental Dermatology最新文献

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Tertiary lymphoid structures associated with improved prognosis and reduced invasion in advanced extramammary Paget disease. 三级淋巴结构与晚期乳腺外帕吉特病的预后改善和侵袭减少有关。
IF 3.7 4区 医学 Q1 DERMATOLOGY Pub Date : 2025-02-24 DOI: 10.1093/ced/llae439
Tetsuya Magara, Motoki Nakamura, Maki Yoshimitsu, Yukiko Yasui, Shinji Kano, Hiroshi Kato, Akimichi Morita
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引用次数: 0
Keratosis lichenoides chronica with pulmonary tuberculosis: a possible association. 慢性角化苔癣与肺结核:可能的关联
IF 3.7 4区 医学 Q1 DERMATOLOGY Pub Date : 2025-02-24 DOI: 10.1093/ced/llae437
Ratnika, Ketki, Riya, Bhavika Bansal
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引用次数: 0
Dermatopathology. 皮肤病理学。
IF 3.7 4区 医学 Q1 DERMATOLOGY Pub Date : 2025-02-24 DOI: 10.1093/ced/llae452
Peiyu Zhou, Wei Chen, Xueyu Zhang, Hongjie Liu, Lin Wang
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引用次数: 0
Case of a newborn with a neurocristic hamartoma in a congenital melanocytic naevi. 一例新生儿先天性黑素细胞痣中的神经肉瘤。
IF 3.7 4区 医学 Q1 DERMATOLOGY Pub Date : 2025-02-24 DOI: 10.1093/ced/llae408
Nikhil Dwivedi, Katherine Darch, Ilsphi Browne
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引用次数: 0
Biologic Safety and Efficacy in Patients with Down Syndrome and Hidradenitis Suppurativa: A Retrospective Cohort Study.
IF 3.7 4区 医学 Q1 DERMATOLOGY Pub Date : 2025-02-24 DOI: 10.1093/ced/llaf090
Linnea L Westerkam, Karla Santiago-Soltero, Alexandra Charrow, John W Frew, Christopher J Sayed
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引用次数: 0
Epidemiological, clinical and histological characteristics of melanoma in young adults: a 30-year retrospective study (1993-2022). 青壮年黑色素瘤的流行病学、临床和组织学特征:一项为期 30 年的回顾性研究(1993-2022 年)。
IF 3.7 4区 医学 Q1 DERMATOLOGY Pub Date : 2025-02-24 DOI: 10.1093/ced/llae466
Belén Rodríguez-Sánchez, Enrique Rodríguez-Lomba, José Antonio Avilés-Izquierdo

Background: Melanoma in young adults significantly impacts the survival of individuals in this age group. There are few studies that analyse melanoma characteristics in young patients.

Objectives: To describe the epidemiological, clinical and histological characteristics of melanoma in young adults and the temporal trends in these characteristics in recent decades.

Methods: A retrospective observational study was conducted, involving 399 patients with melanoma aged 18-44 years, over a 30-year period (1993-2022). Patients were divided into two groups based on their date of diagnosis (period 1, 1993-2007; period 2, 2008-2022).

Results: Age at diagnosis was higher in period 2 than period 1 (34.3 vs. 36.7 years; P < 0.001). Over time, there was a reduction in median thickness (1.0 vs. 0.68 mm; P = 0.01), a rise in melanomas located on the head and neck [n = 15/230 (6.5%) vs. n = 25/169 (14.8%)] and extremities [n = 97/230 (42.2%) vs. n = 76/169 (45.0%)], and a decrease in melanomas on the trunk [n = 118/230 (51.3%) vs. n = 68/169 (40.2%); P = 0.009]. There was also an increase in lentigo maligna [n = 5/230 (2.3%) vs. n = 5/169 (3.0%)] and superficial spreading melanomas [n = 176/230 (76.5%) vs. n = 142/169 (84.0%)], along with a reduction in nodular types [n = 37/230 (16.1%) vs. n = 10/169 (5.9%); P = 0.01]. In comparison with men, women had a higher prevalence of limb melanoma [n = 125/222 (56.3%) vs. n = 48/177 (27.1%); P < 0.001] and family history of melanoma [n = 26/222 (11.7%) vs. n = 9/177 (5.1%); P = 0.02], thinner melanomas (0.69 vs. 1.10 mm; P = 0.001) and a better prognosis [n = 32/222 (14.4%) vs. n = 37/169 (20.9%) deaths; P = 0.01].

Conclusions: Melanoma diagnoses in young adults are occurring at progressively advanced ages, with a rise in melanomas situated on the head and extremities and in histological types linked to prolonged sun exposure. Strategies such as minimizing sun exposure from a young age and encouraging self-examination could lead to improved survival rates.

背景:年轻人患上黑色素瘤会严重影响这个年龄组的生存。分析年轻患者黑色素瘤特征的研究非常有限。我们旨在描述青壮年黑色素瘤的流行病学、临床和组织学特征及其在过去几十年中的时间趋势:我们开展了一项回顾性观察研究,涉及 399 名年龄在 18-44 岁之间的黑色素瘤患者,时间跨度长达 30 年(1993-2022 年)。根据诊断日期将患者分为两组(第一组,1993-2007 年;第二组,2008-2022 年):结果:确诊时的年龄在最近一期较高(34.3 岁对 37 岁;P=0.001)。随着时间的推移,黑色素瘤的厚度有所减少(1 mm vs 0.68 mm; p=0.01),位于头颈部(6.5% vs 14.8%)和四肢(42.2% vs 45%)的黑色素瘤有所增加,而位于躯干(51.3% vs 40.2%)的黑色素瘤有所减少。3%对40.2%)(P=0.009);恶性扁平苔藓(2.3%对5.3%)和浅表扩散型黑色素瘤(76.5%对84%)增加,结节型黑色素瘤减少(16.1%对5.9%)(P=0.012)。与男性相比,女性的肢端黑色素瘤发病率更高(56.3% 对 27.1%;P=0.012):青壮年黑色素瘤的诊断年龄逐渐增大,位于头部和四肢的黑色素瘤以及与长期日晒有关的组织学类型的黑色素瘤有所增加。从年轻时起就尽量减少阳光照射和鼓励自我检查等策略可提高存活率。
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引用次数: 0
Pustular annular erythema triggered by empagliflozin. Empaglifozin 引发的脓疱性环状红斑。
IF 3.7 4区 医学 Q1 DERMATOLOGY Pub Date : 2025-02-24 DOI: 10.1093/ced/llae373
Celine Dandoy, Jonathan M L White, Dilara Sanak, Véronique Del Marmol, Farida Benhadou
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引用次数: 0
Satisfactory clinical response to erlotinib in a patient with Olmsted syndrome. 一名被诊断为奥姆斯特德综合征的患者对厄洛替尼有满意的临床反应
IF 3.7 4区 医学 Q1 DERMATOLOGY Pub Date : 2025-02-24 DOI: 10.1093/ced/llae447
Ayse Oktem, Feride Ongun, Hatice Sanli, Halil Karabulut, Can Leblebici
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引用次数: 0
Topical steroid withdrawal response to Ciclosporin.
IF 3.7 4区 医学 Q1 DERMATOLOGY Pub Date : 2025-02-24 DOI: 10.1093/ced/llaf087
Niamh T McSwiney, Anthony Bewley
{"title":"Topical steroid withdrawal response to Ciclosporin.","authors":"Niamh T McSwiney, Anthony Bewley","doi":"10.1093/ced/llaf087","DOIUrl":"https://doi.org/10.1093/ced/llaf087","url":null,"abstract":"","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143491023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Skin oncology. 雅典娜:皮肤肿瘤学专业证书考试案例。
IF 3.7 4区 医学 Q1 DERMATOLOGY Pub Date : 2025-02-24 DOI: 10.1093/ced/llae387
Gia Toan Tang, Gwyneth Natalie Wong, Alexander Nirenberg, Laura Scardamaglia
{"title":"Skin oncology.","authors":"Gia Toan Tang, Gwyneth Natalie Wong, Alexander Nirenberg, Laura Scardamaglia","doi":"10.1093/ced/llae387","DOIUrl":"10.1093/ced/llae387","url":null,"abstract":"","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":"675-677"},"PeriodicalIF":3.7,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142342752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Clinical and Experimental Dermatology
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