{"title":"Collecting Gender Identity Data in Transgender Dermatology Research: An Ethical Dilemma.","authors":"Aditya Dutt, Richard J Moraga, John G Zampella","doi":"10.1093/ced/llag041","DOIUrl":"https://doi.org/10.1093/ced/llag041","url":null,"abstract":"","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146040401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aubre Gilbert, Atif Saleem, Youn H Kim, Michael S Khodadoust, Ryanne A Brown, Roberto A Novoa, Kerri E Rieger
Chronic lymphocytic leukemia (CLL) is the most common type of leukemia in adults. Skin involvement by malignant CLL cells, or leukemia cutis (LC), typically presents as localized or generalized papulonodular lesions. Here we report a series of five patients with CLL who presented with perniosis-like skin findings on the ears, nose, and/or digits. Histopathologic analysis of seven skin specimens from these five patients showed a relatively dense, nodular to diffuse, pan-dermal infiltrate of monomorphic lymphocytes, compatible with CLL. The typical histopathologic findings of perniosis, such as a robust perivascular and peri-eccrine infiltrate, dermal edema, and interface change, were absent. In one patient, the skin findings heralded the diagnosis of CLL, and in most patients the skin lesions tended to improve with systemic treatment of the patient's underlying CLL. We suggest the term 'leukemic pernio' for cases of leukemia cutis that clinically mimic perniosis.
{"title":"\"Leukemic pernio\": perniosis-like presentations of chronic lymphocytic leukemia.","authors":"Aubre Gilbert, Atif Saleem, Youn H Kim, Michael S Khodadoust, Ryanne A Brown, Roberto A Novoa, Kerri E Rieger","doi":"10.1093/ced/llag030","DOIUrl":"https://doi.org/10.1093/ced/llag030","url":null,"abstract":"<p><p>Chronic lymphocytic leukemia (CLL) is the most common type of leukemia in adults. Skin involvement by malignant CLL cells, or leukemia cutis (LC), typically presents as localized or generalized papulonodular lesions. Here we report a series of five patients with CLL who presented with perniosis-like skin findings on the ears, nose, and/or digits. Histopathologic analysis of seven skin specimens from these five patients showed a relatively dense, nodular to diffuse, pan-dermal infiltrate of monomorphic lymphocytes, compatible with CLL. The typical histopathologic findings of perniosis, such as a robust perivascular and peri-eccrine infiltrate, dermal edema, and interface change, were absent. In one patient, the skin findings heralded the diagnosis of CLL, and in most patients the skin lesions tended to improve with systemic treatment of the patient's underlying CLL. We suggest the term 'leukemic pernio' for cases of leukemia cutis that clinically mimic perniosis.</p>","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146028692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anupam Das, Bhaskar Dutta, Valeska Padovese, Roderick James Hay, Sidra S Khan
Dermatophytosis is a commonly encountered superficial fungal infection with an affinity for keratin-rich structures, such as skin, hair, and nails. The recently emerging recalcitrant dermatophytosis is a recurrent, relapsing, chronic or persistent disease, which has a significant impact on the social, emotional and financial aspects of a patient's life. Trichophyton indotineae, a newly identified species, unlike its predecessor, has become resistant to conventional therapies. This review highlights the shift of this commonly encountered skin disease from an easily manageable clinical entity to an emerging resistant epidemic. We also discuss why dermatophytosis is being labelled as "designated fungal threat".
{"title":"The Changing Face of Dermatophytosis: from common skin disease to emerging resistant epidemic.","authors":"Anupam Das, Bhaskar Dutta, Valeska Padovese, Roderick James Hay, Sidra S Khan","doi":"10.1093/ced/llag034","DOIUrl":"https://doi.org/10.1093/ced/llag034","url":null,"abstract":"<p><p>Dermatophytosis is a commonly encountered superficial fungal infection with an affinity for keratin-rich structures, such as skin, hair, and nails. The recently emerging recalcitrant dermatophytosis is a recurrent, relapsing, chronic or persistent disease, which has a significant impact on the social, emotional and financial aspects of a patient's life. Trichophyton indotineae, a newly identified species, unlike its predecessor, has become resistant to conventional therapies. This review highlights the shift of this commonly encountered skin disease from an easily manageable clinical entity to an emerging resistant epidemic. We also discuss why dermatophytosis is being labelled as \"designated fungal threat\".</p>","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146040457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eleonora Bongiovanni, Umberto Santaniello, Chiara Astrua, Giovanni Cavaliere, Matteo Giovanni Brizio, Paolo Fava, Luca Conti, Simone Ribero, Pietro Quaglino
{"title":"Managing Metastatic Cutaneous Squamous Cell Carcinoma in VEXAS Syndrome: A Therapeutic Challenge.","authors":"Eleonora Bongiovanni, Umberto Santaniello, Chiara Astrua, Giovanni Cavaliere, Matteo Giovanni Brizio, Paolo Fava, Luca Conti, Simone Ribero, Pietro Quaglino","doi":"10.1093/ced/llag032","DOIUrl":"https://doi.org/10.1093/ced/llag032","url":null,"abstract":"","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146028685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tinea incognito with vellus hair involvement: the feelings and experiences of a patient's mother.","authors":"Yaojia Zhou, Ze-Hu Liu","doi":"10.1093/ced/llag027","DOIUrl":"https://doi.org/10.1093/ced/llag027","url":null,"abstract":"","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146017797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Magí Brufau-Cochs, Sofia Gómez-Martínez, Francisco Aya, Laura Serra-García, Susana Puig, Josep Malvehy, Sebastian Podlipnik
{"title":"Pembrolizumab Therapy Leads to Lentigines Resolution and Tumour Control in a Xeroderma Pigmentosum patient with Advanced Cutaneous Squamous Cell Carcinoma.","authors":"Magí Brufau-Cochs, Sofia Gómez-Martínez, Francisco Aya, Laura Serra-García, Susana Puig, Josep Malvehy, Sebastian Podlipnik","doi":"10.1093/ced/llag029","DOIUrl":"https://doi.org/10.1093/ced/llag029","url":null,"abstract":"","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146028703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bella Ganatra, Margaret Hall-Craggs, Ibby Younis, Peter Ellery, Michael Dunnil, Christopher Bunker
{"title":"Progressive limb induration and skin tightening.","authors":"Bella Ganatra, Margaret Hall-Craggs, Ibby Younis, Peter Ellery, Michael Dunnil, Christopher Bunker","doi":"10.1093/ced/llaf554","DOIUrl":"https://doi.org/10.1093/ced/llaf554","url":null,"abstract":"","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146028783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kotaiba Alenezy, Laura Williams, Elena Ailenei, Nafisat Oyewale
{"title":"Umbilical Cutaneous Endometriosis: A Diagnostic Challenge.","authors":"Kotaiba Alenezy, Laura Williams, Elena Ailenei, Nafisat Oyewale","doi":"10.1093/ced/llag028","DOIUrl":"https://doi.org/10.1093/ced/llag028","url":null,"abstract":"","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146017788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vishvan Naidu, Ali Yalcinkaya, Kristina Semkova, Emma C Benton, Jane Setterfield, Richard W Groves, Thomas J Tul
{"title":"Treatment with mycophenolate mofetil as an adjuvant therapy post-rituximab does not improve treatment outcomes in pemphigus.","authors":"Vishvan Naidu, Ali Yalcinkaya, Kristina Semkova, Emma C Benton, Jane Setterfield, Richard W Groves, Thomas J Tul","doi":"10.1093/ced/llag017","DOIUrl":"https://doi.org/10.1093/ced/llag017","url":null,"abstract":"","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2026-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146003220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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