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The Cervical Intervertebral Foramen 颈椎椎间孔
IF 1.9 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-09-17 DOI: 10.1097/bsd.0000000000001681
Jesse Caballo, Austin Darden, Shahjehan Ahmad, Barrett Boody
Study Design: This is an evidence-based narrative review article. Objective: We hope to provide a primer on cervical intervertebral foramen (cIVF) anatomy for spine surgeons, interventionalists, and physiatrists who regularly treat cervical spine pathology, and encourage further exploration of this topic. Background: This corridor for exiting cervical nerve roots is characterized by its intricate microanatomy involving ligamentous, nervous, and vascular structures. Degenerative changes such as facet hypertrophy and disc herniations alter these relationships, potentially leading to nerve root compression and cervical radiculopathy. Methods: This review synthesizes existing knowledge on the cIVF. Key imaging, cadaveric, and clinical studies serve as a foundation for this anatomic review. Results: We explore topics such as dynamic changes that affect foraminal size and their implications for nerve root compression, the relationship of the dorsal root ganglion to the cervical foramen, and the function and clinical significance of foraminal ligaments, arteries, and veins. Conclusions: Changes in the cIVF are frequently the basis of cervical degenerative pathologies. A comprehensive understanding of its microanatomical structure will allow the practitioner to better treat the underlying disease process causing their symptoms and signs.
研究设计:这是一篇基于证据的叙述性综述文章。研究目的我们希望为经常治疗颈椎病的脊柱外科医生、介入医生和物理治疗师提供有关颈椎椎间孔 (cIVF) 解剖学的入门知识,并鼓励他们进一步探讨这一主题。背景:颈椎神经根出口通道的特点是其微观解剖结构错综复杂,涉及韧带、神经和血管结构。面神经肥大和椎间盘突出等退行性病变会改变这些关系,从而可能导致神经根受压和颈椎病。方法:本综述综合了有关颈椎椎间盘突出症的现有知识。主要的成像、尸体和临床研究为本解剖综述奠定了基础。结果:我们探讨了影响椎间孔大小的动态变化及其对神经根压迫的影响、背根神经节与颈椎椎间孔的关系以及椎间孔韧带、动脉和静脉的功能和临床意义等主题。结论:颈椎退行性病变往往是颈椎椎间孔发生变化的基础。全面了解其微观解剖结构将有助于医生更好地治疗导致症状和体征的潜在疾病过程。
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引用次数: 0
The Utility of Magnetic Resonance Imaging-based Vertebral Bone Quality Scores as a Predictor of Cage Subsidence Following Transforaminal and Posterior Lumbar Interbody Fusion. 基于磁共振成像的椎骨质量评分作为经椎间孔和后路腰椎椎体间融合术后固定架下沉的预测指标的实用性。
IF 1.6 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-09-16 DOI: 10.1097/BSD.0000000000001682
Ara Khoylyan, Mina Y Girgis, Alex Tang, Frank Vazquez, Tan Chen

Study design: Retrospective study.

Objectives: The objectives were to determine whether vertebral bone quality (VBQ) scores are associated with interbody cage subsidence following transforaminal (TLIF) and posterior (PLIF) lumbar interbody fusions and whether there is a clinically sensitive threshold for subsidence.

Background: Interbody cage subsidence following lumbar fusion is a complication that can generate poor surgical outcomes. Prior research has correlated cage subsidence with bone mineral density. VBQ scores derived from magnetic resonance imaging (MRI) have been proposed as a tool for measuring bone mineral density, offering a potential new and convenient preoperative risk assessment tool for subsidence.

Methods: The study involved patients undergoing single-level PLIF or TLIF between 2007 and 2022. Exclusions were for nondegenerative diagnoses, multilevel/revision surgeries, inadequate radiographs, missing immediate postoperative radiographs, and preoperative MRI studies older than 1 year. VBQ was calculated at L1-L4 from preoperative T1-weighted MRI images. Subsidence was assessed by changes in disc height (DH; >2 mm difference) and segmental lordosis (SL; >5 degrees difference) between immediate weight-bearing postoperative and latest postoperative lateral radiographs. Statistical analysis included descriptive and inferential statistics.

Results: Subsidence was observed in 27% (SL parameter) and 47% (DH parameter) of 51 total patients. VBQ scores were significantly associated with cage subsidence based on both SL (odds ratio = 7.750, P = 0.012; correlation coefficient = 0.382, P = 0.006) and DH (odds ratio = 4.074, P = 0.026; correlation coefficient = 0.258, P = 0.057) in the combined TLIF/PLIF cohorts. In the cohort of 36 patients undergoing TLIF, a VBQ of 2.70 yielded 100.0% sensitivity and 46.2% specificity in detecting subsidence with SL measurement (area under the curve = 0.812, P < 0.001) and 86.7% sensitivity and 47.6% specificity with the DH measurement (area under the curve = 0.692, P = 0.033).

Conclusions: We found that MRI-based VBQ scores are effective predictors of cage subsidence following TLIF surgery. A VBQ score of 2.70 demonstrated a reliable model and high sensitivity for doing so, identifying a potential clinical threshold for preoperative subsidence risk assessment.

Level of evidence: Level III.

研究设计回顾性研究:目的:确定椎体骨质量(VBQ)评分是否与经椎间孔型(TLIF)和后路型(PLIF)腰椎椎体间融合术后椎间笼下沉有关,以及是否存在临床敏感的下沉阈值:背景:腰椎融合术后椎间笼下沉是一种并发症,可导致手术效果不佳。背景:腰椎融合术后椎间笼下沉是一种并发症,可导致手术效果不佳。根据磁共振成像(MRI)得出的 VBQ 评分被认为是测量骨矿密度的工具,这提供了一种潜在的、便捷的术前下沉风险评估工具:研究对象为2007年至2022年间接受单层PLIF或TLIF手术的患者。排除了非退行性诊断、多层次/翻修手术、X光片不足、术后即刻X光片缺失以及术前磁共振成像检查时间超过1年的患者。根据术前 T1 加权磁共振成像计算 L1-L4 的 VBQ。通过术后即刻负重和最近一次术后侧位X光片之间椎间盘高度(DH;相差>2毫米)和节段前凸(SL;相差>5度)的变化来评估下沉情况。统计分析包括描述性和推论性统计:在51名患者中,27%(SL参数)和47%(DH参数)的患者出现了下陷。在TLIF/PLIF联合队列中,根据SL(几率比=7.750,P=0.012;相关系数=0.382,P=0.006)和DH(几率比=4.074,P=0.026;相关系数=0.258,P=0.057),VBQ评分与保持架下沉有明显关系。在接受 TLIF 的 36 名患者队列中,VBQ 为 2.70 的 SL 测量在检测下沉方面的灵敏度为 100.0%,特异度为 46.2%(曲线下面积 = 0.812,P < 0.001),DH 测量的灵敏度为 86.7%,特异度为 47.6%(曲线下面积 = 0.692,P = 0.033):我们发现,基于磁共振成像的 VBQ 评分能有效预测 TLIF 手术后的骨笼下沉。2.70分的VBQ评分显示了一个可靠的模型和较高的灵敏度,为术前下沉风险评估确定了一个潜在的临床阈值:证据等级:三级。
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引用次数: 0
Transforaminal Versus Lateral Interbody Fusions for Treatment of Adjacent Segment Disease in the Lumbar Spine 治疗腰椎相邻节段疾病的经椎间融合术与外侧椎间融合术
IF 1.9 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-09-12 DOI: 10.1097/bsd.0000000000001673
Prashant V. Rajan, Mark Megerian, Ansh Desai, Penelope N. Halkiadakis, Nicholas Rabah, Michael D. Shost, Bilal Butt, James E. Showery, Zachary Grabel, Dominic W. Pelle, Jason W. Savage
Study Design: Retrospective comparative study. Objective: This study compared outcomes for patients managed with a lateral approach to interbody fusion [lateral (LLIF) or oblique (OLIF)] versus a posterior (PLIF) or transforaminal interbody fusion (TLIF) for treatment of adjacent segment disease (ASD) above or below a prior lumbar fusion construct. Summary of Background Data: No study has compared outcomes of lateral approaches to more traditional posterior approaches for the treatment of ASD. Methods: Retrospective review was performed of patients who underwent single-level lateral or posterior approaches for lumbar interbody fusion for symptomatic ASD between January 2010 and December 2021. Exclusion criteria included skeletal immaturity (age below 18 y old) and surgery indication for malignancy or infection. Patient demographics, medical comorbidities, operative details, postoperative complications, and revision surgery profiles were collected for all patients. Standard descriptive statistics were used to summarize data. Comparative statistical analyses were performed using Statistical Package for the Social Sciences (Version 28.0.1.0; Chicago, IL). Results: A total of 152 patients (65±10 y) were included in the study with a mean duration of follow-up of 1.6±1.4 years. The cohort included 123 PLIF/TLIF (81%), 18 LLIF (12%), 11 OLIF (7%). TLIF/PLIF experienced greater mean operative time (210±62 min vs. 184±80 OLIF/105±64 LLIF, P<0.001) and estimated blood loss (414±254 mL vs. 49±29 OLIF/36±33 LLIF, P<0.001). No significant difference in rate of postoperative complications. Postoperative radicular pain was significantly greater in OLIF (7, 64%) and LLIF (7, 39%) compared with PLIF/TLIF (16, 13%), P<0.001. No statistically significant difference in health care utilization was noted between the groups. Conclusion: Lateral fusions to treat ASD demonstrated no significantly different risk of complication compared with posterior approaches. Our study demonstrated significantly increased operative time and estimated blood loss for the posterior approach and an increased risk of radicular pain from manipulation/retraction of psoas following lateral approaches. Level of Evidence: Level III.
研究设计:回顾性比较研究。研究目的本研究比较了采用侧位椎体间融合术(侧位(LLIF)或斜位(OLIF))与后位(PLIF)或经椎孔椎体间融合术(TLIF)治疗既往腰椎融合术结构上方或下方邻近节段疾病(ASD)患者的疗效。背景数据摘要:还没有研究比较过侧方入路与更传统的后方入路治疗 ASD 的效果。方法:对 2010 年 1 月至 2021 年 12 月间因症状性 ASD 而接受单侧或后路腰椎椎间融合术的患者进行回顾性研究。排除标准包括骨骼不成熟(年龄低于18岁)、手术指征为恶性肿瘤或感染。研究人员收集了所有患者的人口统计学资料、合并症、手术细节、术后并发症和翻修手术资料。数据汇总采用标准描述性统计方法。使用社会科学统计软件包(28.0.1.0 版;伊利诺伊州芝加哥市)进行比较统计分析。结果研究共纳入 152 名患者(65±10 岁),平均随访时间为 1.6±1.4 年。其中包括123例PLIF/TLIF(81%)、18例LLIF(12%)和11例OLIF(7%)。TLIF/PLIF的平均手术时间(210±62 min vs. 184±80 OLIF/105±64 LLIF,P<0.001)和估计失血量(414±254 mL vs. 49±29 OLIF/36±33 LLIF,P<0.001)更长。术后并发症发生率无明显差异。与PLIF/TLIF(16,13%)相比,OLIF(7,64%)和LLIF(7,39%)术后根性疼痛明显更严重,P<0.001。两组患者在使用医疗服务方面没有明显的统计学差异。结论:侧位融合术治疗 ASD 的并发症风险与后位方法相比无明显差异。我们的研究表明,后路方法的手术时间和估计失血量明显增加,侧路方法操作/牵拉腰肌导致根性疼痛的风险增加。证据等级:三级。
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引用次数: 0
Pharmacologic Therapy for Spinal Cord Injury 脊髓损伤的药物治疗
IF 1.9 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-09-12 DOI: 10.1097/bsd.0000000000001695
Brandon A. Sherrod, Ken Porche, Chad K. Condie, Andrew T. Dailey
Neuroprotective strategies aimed at preventing secondary neurologic injury following acute spinal cord injury remain an important area of clinical, translational, and basic science research. Despite recent advancement in the understanding of basic mechanisms of primary and secondary neurologic injury, few pharmacologic agents have shown consistent promise in improving neurologic outcomes following SCI in large randomized clinical trials. The authors review the existing literature and clinical guidelines for pharmacologic therapy investigated for managing acute SCI, including corticosteroids, GM-1 ganglioside (Sygen), Riluzole, opioid antagonists, Cethrin, minocycline, and vasopressors for mean arterial pressure augmentation. Therapies for managing secondary effects of SCI, such as bradycardia, are discussed. Current clinical trials for pharmacotherapy and cellular transplantation following acute SCI are also reviewed. Despite the paucity of current evidence for clinically beneficial post-SCI pharmacotherapy, future research efforts will hopefully elucidate promising therapeutic agents to improve neurologic function.
旨在预防急性脊髓损伤后继发性神经损伤的神经保护策略仍然是临床、转化和基础科学研究的一个重要领域。尽管近年来人们对原发性和继发性神经损伤的基本机制有了更深入的了解,但在大型随机临床试验中,很少有药物能持续改善脊髓损伤后的神经功能预后。作者回顾了现有文献和临床指南中关于治疗急性 SCI 的药物疗法的研究,包括皮质类固醇、GM-1 神经节苷脂(Sygen)、利鲁唑、阿片类拮抗剂、Cethrin、米诺环素和用于增加平均动脉压的血管加压药。此外,还讨论了控制 SCI 继发性影响(如心动过缓)的疗法。此外,还回顾了急性 SCI 后药物治疗和细胞移植的当前临床试验。尽管目前对 SCI 后药物治疗有临床益处的证据不足,但未来的研究工作有望阐明有希望改善神经功能的治疗药物。
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引用次数: 0
The Effect of a Cervical Brace on Postoperative Axial Symptoms Following Single-level Anterior Cervical Discectomy and Fusion 颈椎支架对单层前路颈椎椎间盘切除和融合术术后轴向症状的影响
IF 1.9 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-09-10 DOI: 10.1097/bsd.0000000000001696
Qunfei Yu, Ying Ren, Zhan Wang, Guoping Xu, Yaojing Ma, Feifei Ye
Study Design: Retrospective study. Objective: This study aims to investigate the effect of cervical brace utilization on postoperative axial symptoms in patients undergoing single-segment anterior cervical discectomy and fusion (ACDF). Summary of Background Data: Anterior cervical discectomy and fusion (ACDF) is the most commonly used surgical method in the treatment of cervical spondylosis. For patients with single-segment ACDF. The absence of a neck brace after surgery is safe and does not affect the outcome of surgery. However, the effect on the incidence of AS is unclear. Methods: Patients who underwent anterior cervical single-segment ACDF between May 2020 and August 2021 were retrospectively analyzed. Participants were divided into brace group and nonbraced groups. The incidence of axial symptoms, cervical mobility, and postoperative quality of life were then compared between the 2 groups. Results: A total of 121 patients were included in this study: 62 in the brace group and 59 in the nonbraced group. There were no statistically significant variations observed in the overall demographic characteristics, including age, sex, body mass index, smoking status, and disease duration. The study findings showed that there was a significant decrease in the occurrence of axial symptoms among patients in nonbraced group, in addition to a considerable increase in cervical mobility 1 month following the surgery. Conclusions: The omission of a cervical brace following surgery in patients undergoing single-segment ACDF reduced the incidence of early postoperative axial symptoms, improved their overall quality of life, and facilitated the recovery of postoperative cervical mobility.
研究设计:回顾性研究。研究目的本研究旨在探讨使用颈椎支架对接受单节段颈椎前路椎间盘切除和融合术(ACDF)患者术后轴向症状的影响。背景数据摘要:颈椎前路椎间盘切除融合术(ACDF)是治疗颈椎病最常用的手术方法。对于单节段 ACDF 患者而言。术后不使用颈托是安全的,也不会影响手术效果。但对强直性脊柱炎发病率的影响尚不清楚。方法:对 2020 年 5 月至 2021 年 8 月间接受颈椎前路单节段 ACDF 的患者进行回顾性分析。参与者分为支架组和无支架组。然后比较两组患者的轴向症状发生率、颈椎活动度和术后生活质量。结果:本研究共纳入 121 名患者:支架组 62 人,无支架组 59 人。在整体人口统计学特征(包括年龄、性别、体重指数、吸烟状况和病程)方面没有观察到明显的差异。研究结果表明,无支架组患者的轴向症状明显减少,而且术后一个月颈椎活动度显著增加。研究结论接受单节段 ACDF 手术的患者术后不使用颈椎支架可减少术后早期轴向症状的发生率,改善患者的整体生活质量,并促进术后颈椎活动度的恢复。
{"title":"The Effect of a Cervical Brace on Postoperative Axial Symptoms Following Single-level Anterior Cervical Discectomy and Fusion","authors":"Qunfei Yu, Ying Ren, Zhan Wang, Guoping Xu, Yaojing Ma, Feifei Ye","doi":"10.1097/bsd.0000000000001696","DOIUrl":"https://doi.org/10.1097/bsd.0000000000001696","url":null,"abstract":"Study Design: Retrospective study. Objective: This study aims to investigate the effect of cervical brace utilization on postoperative axial symptoms in patients undergoing single-segment anterior cervical discectomy and fusion (ACDF). Summary of Background Data: Anterior cervical discectomy and fusion (ACDF) is the most commonly used surgical method in the treatment of cervical spondylosis. For patients with single-segment ACDF. The absence of a neck brace after surgery is safe and does not affect the outcome of surgery. However, the effect on the incidence of AS is unclear. Methods: Patients who underwent anterior cervical single-segment ACDF between May 2020 and August 2021 were retrospectively analyzed. Participants were divided into brace group and nonbraced groups. The incidence of axial symptoms, cervical mobility, and postoperative quality of life were then compared between the 2 groups. Results: A total of 121 patients were included in this study: 62 in the brace group and 59 in the nonbraced group. There were no statistically significant variations observed in the overall demographic characteristics, including age, sex, body mass index, smoking status, and disease duration. The study findings showed that there was a significant decrease in the occurrence of axial symptoms among patients in nonbraced group, in addition to a considerable increase in cervical mobility 1 month following the surgery. Conclusions: The omission of a cervical brace following surgery in patients undergoing single-segment ACDF reduced the incidence of early postoperative axial symptoms, improved their overall quality of life, and facilitated the recovery of postoperative cervical mobility.","PeriodicalId":10457,"journal":{"name":"Clinical Spine Surgery","volume":"6 1","pages":""},"PeriodicalIF":1.9,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142209976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preoperative Serum Albumin and TLC as Predictors of Postoperative Complications in Spine Surgery 预测脊柱手术术后并发症的术前血清白蛋白和 TLC
IF 1.9 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-09-10 DOI: 10.1097/bsd.0000000000001685
Ayman Mohamed, Connor Sheehan, Paramveer Kaur, Frank Schwab, Alexander Butler
Study Design: Narrative review. Purpose: To investigate the state of literature regarding serum albumin and total lymphocyte count and their associations with postoperative complications after spine surgery. Methods: Comprehensive search of the PubMed database was performed to find relevant articles addressing preoperative serum albumin, total lymphocyte count, or their respective composite scores and their associations with postoperative complications after spine surgery. Summary of Background Data: Serum albumin level is frequently cited as a marker of patient nutritional status. Total lymphocyte count has more recently gained attention in the literature for similar reasons. Identification of modifiable preoperative patient risk factors for postoperative complications such as malnutrition may help minimize the incidence of postoperative complications. Results: Review of the literature revealed 10 studies that discussed the association between preoperative hypoalbuminemia and postoperative complications. Five studies examined the relationship between either prognostic nutritional index (PNI), controlling nutritional status (CONUT), or both and postoperative complications after spine surgery. Preoperative hypoalbuminemia, low PNI, and high CONUT scores were associated with increased risk of postoperative complications after spine surgery. Conclusions: Preoperative malnourishment is a modifiable patient factor that is associated with an increased risk of postoperative complications after spine surgery.
研究设计:叙述性综述。目的:调查有关脊柱手术后血清白蛋白和总淋巴细胞计数及其与术后并发症关系的文献现状。方法: 对 PubMed 进行全面搜索:对 PubMed 数据库进行全面检索,以找到关于术前血清白蛋白、总淋巴细胞计数或其各自的综合评分及其与脊柱手术后并发症的关系的相关文章。背景数据摘要:血清白蛋白水平经常被用作患者营养状况的标志。由于类似的原因,总淋巴细胞计数最近在文献中也受到了关注。确定患者术前可改变的术后并发症风险因素(如营养不良)有助于将术后并发症的发生率降至最低。结果:文献回顾显示,有 10 项研究讨论了术前低白蛋白血症与术后并发症之间的关系。五项研究探讨了预后营养指数 (PNI)、控制营养状况 (CONUT) 或两者与脊柱手术后并发症之间的关系。术前低白蛋白血症、低 PNI 和高 CONUT 评分与脊柱手术后并发症风险增加有关。结论:术前营养不良是一个可改变的患者因素,与脊柱手术后并发症风险增加有关。
{"title":"Preoperative Serum Albumin and TLC as Predictors of Postoperative Complications in Spine Surgery","authors":"Ayman Mohamed, Connor Sheehan, Paramveer Kaur, Frank Schwab, Alexander Butler","doi":"10.1097/bsd.0000000000001685","DOIUrl":"https://doi.org/10.1097/bsd.0000000000001685","url":null,"abstract":"Study Design: Narrative review. Purpose: To investigate the state of literature regarding serum albumin and total lymphocyte count and their associations with postoperative complications after spine surgery. Methods: Comprehensive search of the PubMed database was performed to find relevant articles addressing preoperative serum albumin, total lymphocyte count, or their respective composite scores and their associations with postoperative complications after spine surgery. Summary of Background Data: Serum albumin level is frequently cited as a marker of patient nutritional status. Total lymphocyte count has more recently gained attention in the literature for similar reasons. Identification of modifiable preoperative patient risk factors for postoperative complications such as malnutrition may help minimize the incidence of postoperative complications. Results: Review of the literature revealed 10 studies that discussed the association between preoperative hypoalbuminemia and postoperative complications. Five studies examined the relationship between either prognostic nutritional index (PNI), controlling nutritional status (CONUT), or both and postoperative complications after spine surgery. Preoperative hypoalbuminemia, low PNI, and high CONUT scores were associated with increased risk of postoperative complications after spine surgery. Conclusions: Preoperative malnourishment is a modifiable patient factor that is associated with an increased risk of postoperative complications after spine surgery.","PeriodicalId":10457,"journal":{"name":"Clinical Spine Surgery","volume":"3 1","pages":""},"PeriodicalIF":1.9,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142209892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cervical Disc Arthroplasty Device Failure Causing Progressive Cervical Myelopathy and Requiring Revision Cervical Corpectomy. 颈椎间盘关节置换术装置故障导致渐进性颈椎脊髓病,需要进行颈椎后路切除术。
IF 1.6 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-09-09 DOI: 10.1097/BSD.0000000000001691
Jonathan Parish, Steve H Monk, Matthew O'Brien, Ummey Hani, Domagoj Coric, Christopher M Holland

Background: Cervical disc arthroplasty is a well-established alternative to anterior cervical fusion but requires precise placement for optimal outcomes. We present the case of a 2-level cervical disc arthroplasty with suboptimal implantation of the interbody devices, requiring revision corpectomy. Supplemental video, Supplemental Digital Content 1 (http://links.lww.com/CLINSPINE/A358) content of the revision surgery is also provided. This report highlights the importance of proper implant sizing and position and reviews the nuances of surgical revision.

Methods: A retrospective review of the clinical and radiographic data was performed from prior to the index operation through the 3-month postoperative period after the surgical revision.

Results: The patient presented approximately 2 years post-cervical arthroplasty with increasing neck pain and early cervical myelopathy. An imaging workup revealed severe cervical stenosis at the caudal level with cord compression and concern for device failure. Intraoperatively, the core of the caudal device was found to have ejected into the spinal canal. A cervical corpectomy of the intervening vertebra with the removal of both devices was performed. The patient had a complete neurologic recovery.

Conclusion: Although failure of a cervical disc arthroplasty device is rare, the likelihood can be significantly increased with poor sizing (over or under sizing), asymmetric placement, endplate violation, or poor patient selection. In the case presented herein, early device failure was unrecognized, and the patient went on to develop progressive cervical myelopathy requiring revision corpectomy.

背景:颈椎间盘关节置换术是一种行之有效的颈椎前路融合术替代方法,但需要精确植入才能达到最佳效果。我们介绍了一例 2 水平颈椎间盘关节置换术,该手术的椎体间装置植入效果不佳,需要进行翻修性椎体后凸切除术。我们还提供了翻修手术的补充视频、补充数字内容 1 (http://links.lww.com/CLINSPINE/A358)。本报告强调了正确植入物大小和位置的重要性,并回顾了翻修手术的细微差别:方法:回顾性审查了从指数手术前到手术翻修后 3 个月的临床和影像学数据:患者在颈椎关节置换术后约两年出现颈部疼痛加剧和早期颈椎病。影像学检查显示尾椎水平颈椎严重狭窄,伴有脊髓压迫,担心装置会出现故障。术中发现,尾椎装置的核心部分弹入椎管。患者接受了间隔椎体的颈椎椎体切除术,并取出了两个装置。患者的神经功能完全恢复:结论:尽管颈椎间盘关节置换术器械出现故障的情况很少见,但如果尺寸选择不当(过大或过小)、置放位置不对称、椎板末端受侵犯或患者选择不当,故障的可能性就会大大增加。在本病例中,早期装置失效未被察觉,患者后来发展为渐进性颈椎脊髓病,需要进行翻修性椎间盘切除术。
{"title":"Cervical Disc Arthroplasty Device Failure Causing Progressive Cervical Myelopathy and Requiring Revision Cervical Corpectomy.","authors":"Jonathan Parish, Steve H Monk, Matthew O'Brien, Ummey Hani, Domagoj Coric, Christopher M Holland","doi":"10.1097/BSD.0000000000001691","DOIUrl":"https://doi.org/10.1097/BSD.0000000000001691","url":null,"abstract":"<p><strong>Background: </strong>Cervical disc arthroplasty is a well-established alternative to anterior cervical fusion but requires precise placement for optimal outcomes. We present the case of a 2-level cervical disc arthroplasty with suboptimal implantation of the interbody devices, requiring revision corpectomy. Supplemental video, Supplemental Digital Content 1 (http://links.lww.com/CLINSPINE/A358) content of the revision surgery is also provided. This report highlights the importance of proper implant sizing and position and reviews the nuances of surgical revision.</p><p><strong>Methods: </strong>A retrospective review of the clinical and radiographic data was performed from prior to the index operation through the 3-month postoperative period after the surgical revision.</p><p><strong>Results: </strong>The patient presented approximately 2 years post-cervical arthroplasty with increasing neck pain and early cervical myelopathy. An imaging workup revealed severe cervical stenosis at the caudal level with cord compression and concern for device failure. Intraoperatively, the core of the caudal device was found to have ejected into the spinal canal. A cervical corpectomy of the intervening vertebra with the removal of both devices was performed. The patient had a complete neurologic recovery.</p><p><strong>Conclusion: </strong>Although failure of a cervical disc arthroplasty device is rare, the likelihood can be significantly increased with poor sizing (over or under sizing), asymmetric placement, endplate violation, or poor patient selection. In the case presented herein, early device failure was unrecognized, and the patient went on to develop progressive cervical myelopathy requiring revision corpectomy.</p>","PeriodicalId":10457,"journal":{"name":"Clinical Spine Surgery","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142153306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Research Progress of Camptocormia in Parkinson Disease. 帕金森病的 Camptocormia 研究进展。
IF 1.6 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-09-09 DOI: 10.1097/BSD.0000000000001674
Yilin Lu, Xiang Zhang, Junyu Li, Weishi Li, Miao Yu

Camptocormia, also known as bent spine syndrome, primarily affects individuals with Parkinson disease (PD). This review provides an overview of camptocormia in PD, covering its definition, epidemiology, causes, diagnosis, and treatment. In the epidemiology section, we delve into its prevalence, gender disparities, and ongoing genetic research. Regarding diagnosis and assessment, we discuss evolving diagnostic criteria and measurement techniques, as well as new diagnostic tools. For management and treatment, a wide array of options is available, from conservative methods such as physical therapy and botulinum toxin injections to surgical interventions such as spinal orthopedic surgery and deep brain stimulation. We stress the significance of personalized care and multidisciplinary collaboration. This comprehensive review aims to provide clinicians, researchers, and healthcare professionals with a comprehensive understanding of camptocormia in PD, highlighting its clinical features, diagnostic strategies, management approaches, and future perspectives.

驼背症又称脊柱弯曲综合征,主要影响帕金森病(PD)患者。本综述概述了帕金森病中的驼背症,包括其定义、流行病学、病因、诊断和治疗。在流行病学部分,我们将深入探讨其发病率、性别差异以及正在进行的遗传学研究。在诊断和评估方面,我们讨论了不断发展的诊断标准和测量技术,以及新的诊断工具。在管理和治疗方面,有多种选择,从物理治疗和肉毒杆菌毒素注射等保守方法到脊柱矫形手术和脑深部刺激等外科干预措施。我们强调个性化护理和多学科协作的重要性。这篇全面的综述旨在让临床医生、研究人员和医疗保健专业人员全面了解帕金森病的凸轮畸形,突出其临床特征、诊断策略、管理方法和未来展望。
{"title":"Research Progress of Camptocormia in Parkinson Disease.","authors":"Yilin Lu, Xiang Zhang, Junyu Li, Weishi Li, Miao Yu","doi":"10.1097/BSD.0000000000001674","DOIUrl":"https://doi.org/10.1097/BSD.0000000000001674","url":null,"abstract":"<p><p>Camptocormia, also known as bent spine syndrome, primarily affects individuals with Parkinson disease (PD). This review provides an overview of camptocormia in PD, covering its definition, epidemiology, causes, diagnosis, and treatment. In the epidemiology section, we delve into its prevalence, gender disparities, and ongoing genetic research. Regarding diagnosis and assessment, we discuss evolving diagnostic criteria and measurement techniques, as well as new diagnostic tools. For management and treatment, a wide array of options is available, from conservative methods such as physical therapy and botulinum toxin injections to surgical interventions such as spinal orthopedic surgery and deep brain stimulation. We stress the significance of personalized care and multidisciplinary collaboration. This comprehensive review aims to provide clinicians, researchers, and healthcare professionals with a comprehensive understanding of camptocormia in PD, highlighting its clinical features, diagnostic strategies, management approaches, and future perspectives.</p>","PeriodicalId":10457,"journal":{"name":"Clinical Spine Surgery","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142153307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Increased Change in Cervical Lordosis is Associated With Decreased Rate of Recovery in Patients With C5 Palsy. 颈椎前凸变化的增加与 C5 麻痹患者康复率的降低有关。
IF 1.6 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-09-03 DOI: 10.1097/BSD.0000000000001680
Joseph N Frazzetta, Nathan Pecoraro, Ignacio Jusue-Torres, Paul M Arnold, Ryan Hofler, G Alexander Jones, Russ Nockels

Study design: A retrospective chart review.

Objective: The authors aim to investigate the role of clinical and radiographic parameters in patients who underwent posterior cervical surgery, and their association with C5 palsy severity and time to recovery.

Background: Postoperative C5 palsy affects 1%-30% of patients undergoing posterior decompression, with or without fusion. Causation and avoidance of this complication remain widely debated.

Materials and methods: A single institution review of patients who underwent posterior cervical spine surgery was focused on using specific Common Procedural Technology codes associated with the patient population of interest. Patients were excluded if they had inadequate pre and postoperative imaging, as well as a history of prior cervical spine surgery, concurrent anterior surgery, intradural pathology, spinal tumor, or spinal trauma. Radiographic measurements of the pre and postoperative images were completed with subsequent intraclass correlation coefficient analysis to confirm the precision of measurements.

Results: Out of 105 total patients, 35 (33%) patients developed a C5 palsy. Twenty-four (69%) of those palsies completely resolved, with a median time to recovery of 8 months. Preoperative demographics and radiographic parameters demonstrated heterogeneity among those patients who did and did not have a resolution of palsy. Patients with increased change in C2-C7 lordosis (P = 0.011) after surgery were associated with decreased likelihood of recovery. Patients without a smoking history (P = 0.009) had an increased likelihood of recovering from C5 palsy.

Conclusions: The degree of increased lordosis in the treatment of degenerative cervical disease plays a role in the rate of recovery from C5 palsy. This should be considered during preoperative planning in determining the amount of lordosis desired. In addition, patients without a smoking history were associated with a higher rate of recovery.

Level of evidence: Level IV.

研究设计回顾性病历审查:作者旨在研究颈椎后路手术患者的临床和影像学参数的作用,以及它们与C5麻痹严重程度和恢复时间的关系:背景:1%-30%接受后路减压术(无论有无融合)的患者术后会出现C5麻痹。背景:1%-30%接受后路减压术并行或不行椎间融合术的患者会出现术后C5麻痹,对这一并发症的成因和避免仍存在广泛争议:对接受颈椎后路手术的患者进行单一机构审查,重点是使用与相关患者群体相关的特定通用程序技术代码。如果患者术前和术后的影像学检查结果不充分,且曾接受过颈椎手术、同时接受过前路手术、硬膜内病变、脊柱肿瘤或脊柱外伤,则将其排除在外。对术前和术后图像进行放射学测量,随后进行类内相关系数分析,以确认测量的精确性:在105名患者中,有35名(33%)患者出现了C5瘫痪。其中 24 例(69%)完全康复,中位康复时间为 8 个月。术前人口统计学和放射学参数显示,麻痹缓解和未缓解的患者之间存在异质性。术后C2-C7前凸变化增加(P = 0.011)的患者康复的可能性降低。无吸烟史的患者(P = 0.009)从C5麻痹中恢复的可能性增加:结论:在治疗颈椎退行性疾病时,颈椎前凸的增加程度对 C5 麻痹的康复率有影响。在术前规划时应考虑到这一点,以确定所需的前凸程度。此外,无吸烟史的患者康复率更高:证据等级:IV 级。
{"title":"Increased Change in Cervical Lordosis is Associated With Decreased Rate of Recovery in Patients With C5 Palsy.","authors":"Joseph N Frazzetta, Nathan Pecoraro, Ignacio Jusue-Torres, Paul M Arnold, Ryan Hofler, G Alexander Jones, Russ Nockels","doi":"10.1097/BSD.0000000000001680","DOIUrl":"https://doi.org/10.1097/BSD.0000000000001680","url":null,"abstract":"<p><strong>Study design: </strong>A retrospective chart review.</p><p><strong>Objective: </strong>The authors aim to investigate the role of clinical and radiographic parameters in patients who underwent posterior cervical surgery, and their association with C5 palsy severity and time to recovery.</p><p><strong>Background: </strong>Postoperative C5 palsy affects 1%-30% of patients undergoing posterior decompression, with or without fusion. Causation and avoidance of this complication remain widely debated.</p><p><strong>Materials and methods: </strong>A single institution review of patients who underwent posterior cervical spine surgery was focused on using specific Common Procedural Technology codes associated with the patient population of interest. Patients were excluded if they had inadequate pre and postoperative imaging, as well as a history of prior cervical spine surgery, concurrent anterior surgery, intradural pathology, spinal tumor, or spinal trauma. Radiographic measurements of the pre and postoperative images were completed with subsequent intraclass correlation coefficient analysis to confirm the precision of measurements.</p><p><strong>Results: </strong>Out of 105 total patients, 35 (33%) patients developed a C5 palsy. Twenty-four (69%) of those palsies completely resolved, with a median time to recovery of 8 months. Preoperative demographics and radiographic parameters demonstrated heterogeneity among those patients who did and did not have a resolution of palsy. Patients with increased change in C2-C7 lordosis (P = 0.011) after surgery were associated with decreased likelihood of recovery. Patients without a smoking history (P = 0.009) had an increased likelihood of recovering from C5 palsy.</p><p><strong>Conclusions: </strong>The degree of increased lordosis in the treatment of degenerative cervical disease plays a role in the rate of recovery from C5 palsy. This should be considered during preoperative planning in determining the amount of lordosis desired. In addition, patients without a smoking history were associated with a higher rate of recovery.</p><p><strong>Level of evidence: </strong>Level IV.</p>","PeriodicalId":10457,"journal":{"name":"Clinical Spine Surgery","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142119084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spinal Dural Ectasia Spectrum: Management of Two Cases and Systematic Review of the Therapeutic Options. 脊髓硬脊膜外翻症谱:两例病例的处理和治疗方案的系统回顾。
IF 1.6 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-09-03 DOI: 10.1097/BSD.0000000000001678
Raffaele De Marco, Silvia Sgambetterra, Luigi Aurelio Nasto, Gianluca Piatelli, Marco Pavanello

Objective: To describe 2 cases with pathologic expansion of lumbosacral dura mater exerting compression on lumbosacral nerves treated with placement of lumboperitoneal shunt (LPS). Although dural ectasia (DE) is asymptomatic in most cases, a systematic review of the literature was performed focusing on the management when it causes symptoms.

Methods: Pubmed/Medline and Embase databases were searched for the surgical management of DE. Both pediatric and adult patients were included. The presence of a cerebrospinal fluid leak was considered an exclusion criterion. An additional search was performed to provide a more complete picture of the DE spectrum considering meningoceles as a severe form of dural expansion.

Results: Differentiating DE from meningocele, only 20 patients were treated for symptomatic DE. Surgical management varied according to presentation and etiopathogenesis: blood patch or fibrin glue were attempted in case of intracranial hypotension, followed eventually by LPS or marsupialization or dura reduction in cases of failure, whereas LPS or spinal decompression were proposed in cases of radiculopathy or cauda equina syndrome.

Conclusion: DE is a rare condition mostly associated with connective tissue disorders. The different etiopathogenesis may explain how it causes symptoms in specific conditions. Treatments should be chosen according to this and may be proposed at the appearance of symptoms since dural expansion is a self-sustained mechanism.

目的描述两例腰骶部硬脑膜病理扩张压迫腰骶神经并接受腰腹腔分流术(LPS)治疗的病例。虽然硬脊膜异位症(DE)在大多数情况下没有症状,但我们还是对相关文献进行了系统性回顾,重点研究了导致症状的处理方法:方法:检索了 Pubmed/Medline 和 Embase 数据库中有关硬脑膜异位症手术治疗的文献。包括儿童和成人患者。存在脑脊液漏被视为排除标准。考虑到脑膜瘤是硬脑膜扩张的一种严重形式,为了更全面地了解硬脑膜瘤的病谱,还进行了额外的检索:结果:将硬脑膜膨出与脑膜囊肿区分开来,只有20名患者因有症状的硬脑膜膨出而接受了治疗。手术治疗因表现和发病机制而异:颅内低血压者尝试血补片或纤维蛋白胶,失败者最终采用LPS或沼泽化或硬脑膜减张术,而出现根神经病变或马尾综合征者则建议采用LPS或脊柱减压术:结论:DE是一种罕见病,大多与结缔组织病有关。结论:DE 是一种罕见疾病,多与结缔组织病有关。不同的发病机制可能解释了它在特定情况下如何导致症状。由于硬脊膜膨出是一种自我维持机制,因此应根据这一机制选择治疗方法,并可在症状出现时提出治疗建议。
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Clinical Spine Surgery
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