首页 > 最新文献

Open Access Indonesian Journal of Medical Reviews最新文献

英文 中文
Antibacterial Effectiveness Test of Kencur Rhizome Ethanol Extract (Kaempferia galanga L.) against Escherichia coli and Staphylococcus aureus 山柰乙醇提取物对大肠杆菌和金黄色葡萄球菌的抑菌效果试验
Pub Date : 2023-08-14 DOI: 10.37275/oaijmr.v3i4.336
Rr Nadhira, Al Fajrie, Nurhayani
Indonesia is a country with abundant biodiversity. Increased bacterial resistance Escherichia coli and Staphylococcus aureus antibiotics require alternative treatment, one of which is medicinal plants. Kencur (Kaempferia galanga L.) is a medicinal plant that contains saponins, flavonoids, phenols, and tannins, which can inhibit bacterial growth. This study aimed to determine the antibacterial effect of kencur rhizome ethanol extract (Kaempferia galanga L.) against Escherichia coli and Staphylococcus aureus. This research is an experimental laboratory design post-test only control group design. The rhizomes of kencur were extracted using 70% ethanol and tested for antibacterial activity using the well method. There were 6 groups in the study, namely the positive control group using ciprofloxacin, the negative control using distilled water, kencur rhizome ethanol extract concentrations of 12.5%, 25%, 50%, and 100%. The largest diameter of the inhibition zone was found at a concentration of 100%, with an average of 10.18 mm in the bacteria Escherichia coli and 22.47 mm in the bacteria Staphylococcus aureus. In conclusion, the ethanol extract of kencur rhizome (Kaempferia galanga L.) can inhibit the growth of bacteria Escherichia coli and Staphylococcus aureus.
印度尼西亚是一个生物多样性丰富的国家。增加细菌耐药性大肠杆菌和金黄色葡萄球菌抗生素需要替代治疗,其中之一是药用植物。山柰(Kaempferia galanga L.)是一种药用植物,含有皂苷、类黄酮、酚类和单宁,可以抑制细菌的生长。本实验旨在研究山柰乙醇提取物对大肠杆菌和金黄色葡萄球菌的抑菌作用。本研究为实验实验室设计,后测仅为对照组设计。采用70%乙醇提取kencur根茎,用孔法测定其抑菌活性。研究共设6组,阳性对照组使用环丙沙星,阴性对照组使用蒸馏水,根茎乙醇提取物浓度分别为12.5%、25%、50%和100%。当浓度为100%时,抑菌带直径最大,大肠杆菌和金黄色葡萄球菌的平均抑菌带直径分别为10.18 mm和22.47 mm。综上所述,kenemperia galanga L.乙醇提取物可抑制大肠杆菌和金黄色葡萄球菌的生长。
{"title":"Antibacterial Effectiveness Test of Kencur Rhizome Ethanol Extract (Kaempferia galanga L.) against Escherichia coli and Staphylococcus aureus","authors":"Rr Nadhira, Al Fajrie, Nurhayani","doi":"10.37275/oaijmr.v3i4.336","DOIUrl":"https://doi.org/10.37275/oaijmr.v3i4.336","url":null,"abstract":"Indonesia is a country with abundant biodiversity. Increased bacterial resistance Escherichia coli and Staphylococcus aureus antibiotics require alternative treatment, one of which is medicinal plants. Kencur (Kaempferia galanga L.) is a medicinal plant that contains saponins, flavonoids, phenols, and tannins, which can inhibit bacterial growth. This study aimed to determine the antibacterial effect of kencur rhizome ethanol extract (Kaempferia galanga L.) against Escherichia coli and Staphylococcus aureus. This research is an experimental laboratory design post-test only control group design. The rhizomes of kencur were extracted using 70% ethanol and tested for antibacterial activity using the well method. There were 6 groups in the study, namely the positive control group using ciprofloxacin, the negative control using distilled water, kencur rhizome ethanol extract concentrations of 12.5%, 25%, 50%, and 100%. The largest diameter of the inhibition zone was found at a concentration of 100%, with an average of 10.18 mm in the bacteria Escherichia coli and 22.47 mm in the bacteria Staphylococcus aureus. In conclusion, the ethanol extract of kencur rhizome (Kaempferia galanga L.) can inhibit the growth of bacteria Escherichia coli and Staphylococcus aureus.","PeriodicalId":106715,"journal":{"name":"Open Access Indonesian Journal of Medical Reviews","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130518293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of Medical Records Unit Employee Workload During the COVID-19 Pandemic at Mitra Masyarakat Hospital, Mimika, Indonesia 印度尼西亚米米卡Mitra Masyarakat医院COVID-19大流行期间医疗记录部门员工工作量分析
Pub Date : 2023-07-25 DOI: 10.37275/oaijmr.v3i4.325
Amida Morina Raru, Siswati, Deasy Rosmala Dewi, N. Rumana, Amida Morina
The workload of medical record unit staff at a hospital can vary depending on the size and type of hospital, the number of patients, and the internal policies implemented. Medical record unit employees are responsible for collecting, managing, and storing patient medical records. During the COVID-19 pandemic, the workload of employees in the medical records unit greatly increased because there was a surge in patients due to the pandemic. An increase in the number of patients occurred in all hospitals in Indonesia, including Mitra Masyarakat Hospital, Mimika. This study aimed to describe the workload profile of employees in the medical records unit at Mitra Masyarakat Hospital during the COVID-19 pandemic. This research is descriptive observational research. The location of this research is Mitra Masyarakat Hospital, Mimika, Indonesia. The research was conducted from March to August 2021. Data sources were obtained from interviewing informants, observing and measuring workload in the medical record unit before and during the pandemic. The variables measured in this study were available working time, workload standards, supporting task standards, and supporting task factors, as well as the need for human resources in the Mitra Masyarakat Hospital work unit. The results of the study show that the available working time for medical record unit personnel for each section is 1300 hours/year or 78,000 minutes/year. The need for health human resources for the medical record unit is as many as 20 people. There are 9 medical record officers currently owned by RSMM. Thus it can be concluded the number of employees is less when compared to the workload in the medical record unit at Mitra Masyarakat Hospital.  
根据医院的规模和类型、患者数量和实施的内部政策,医院病历单位工作人员的工作量可能有所不同。病案单位员工负责收集、管理和存储患者病历。在新冠肺炎大流行期间,由于患者数量激增,病案部门员工的工作量大大增加。印度尼西亚所有医院的病人人数都有所增加,包括米米卡的米特拉Masyarakat医院。本研究旨在描述Mitra Masyarakat医院医疗记录部门员工在COVID-19大流行期间的工作量概况。本研究为描述性观察性研究。这项研究的地点是印度尼西亚米米卡的Mitra Masyarakat医院。该研究于2021年3月至8月进行。数据来源是通过在大流行之前和期间采访举报人、观察和衡量病历部门的工作量获得的。本研究测量的变量包括:Mitra Masyarakat医院工作单位的可用工作时间、工作量标准、支持任务标准和支持任务因素,以及人力资源需求。研究结果表明,各科病案单位人员的可用工作时间为1300小时/年或78 000分钟/年。医疗记录股需要的卫生人力资源多达20人。目前有9名病案干事归皇家医务管理委员会所有。因此,可以得出结论,与Mitra Masyarakat医院病历科的工作量相比,雇员人数较少。
{"title":"Analysis of Medical Records Unit Employee Workload During the COVID-19 Pandemic at Mitra Masyarakat Hospital, Mimika, Indonesia","authors":"Amida Morina Raru, Siswati, Deasy Rosmala Dewi, N. Rumana, Amida Morina","doi":"10.37275/oaijmr.v3i4.325","DOIUrl":"https://doi.org/10.37275/oaijmr.v3i4.325","url":null,"abstract":"The workload of medical record unit staff at a hospital can vary depending on the size and type of hospital, the number of patients, and the internal policies implemented. Medical record unit employees are responsible for collecting, managing, and storing patient medical records. During the COVID-19 pandemic, the workload of employees in the medical records unit greatly increased because there was a surge in patients due to the pandemic. An increase in the number of patients occurred in all hospitals in Indonesia, including Mitra Masyarakat Hospital, Mimika. This study aimed to describe the workload profile of employees in the medical records unit at Mitra Masyarakat Hospital during the COVID-19 pandemic. This research is descriptive observational research. The location of this research is Mitra Masyarakat Hospital, Mimika, Indonesia. The research was conducted from March to August 2021. Data sources were obtained from interviewing informants, observing and measuring workload in the medical record unit before and during the pandemic. The variables measured in this study were available working time, workload standards, supporting task standards, and supporting task factors, as well as the need for human resources in the Mitra Masyarakat Hospital work unit. The results of the study show that the available working time for medical record unit personnel for each section is 1300 hours/year or 78,000 minutes/year. The need for health human resources for the medical record unit is as many as 20 people. There are 9 medical record officers currently owned by RSMM. Thus it can be concluded the number of employees is less when compared to the workload in the medical record unit at Mitra Masyarakat Hospital. \u0000 ","PeriodicalId":106715,"journal":{"name":"Open Access Indonesian Journal of Medical Reviews","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115457461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Overview of the Development of Language Skills in Toddlers with Prescreening Developmental Questionnaire (PDQ) at Posyandu Anggrek Sukamandi, Sagalaherang District, Subang, Indonesia 印尼苏邦Sagalaherang地区Posyandu Anggrek Sukamandi幼儿语言技能发展的预筛选发展问卷(PDQ)概述
Pub Date : 2023-07-11 DOI: 10.37275/oaijmr.v3i4.321
Noventy Sutarman
At the toddler development stage, namely 1-3 years old, language skills become a very crucial aspect in the process of interaction and communication with the surrounding environment. At this time, children begin to develop vocabulary, speech skills, understand instructions, and express themselves using words. This study aimed to provide an overview of the development of language skills in toddlers at Posyandu Anggrek Sukamandi, Sagalaherang District, Subang, Indonesia. This study was a descriptive observational study. A total of 42 research subjects participated in this study. Univariate analysis was carried out to screen language skills with the PDQ. Toddlers who experience questionable language development are 7.14%. Toddlers with adverse language development were found in 28.57% of toddlers with malnutrition and 3.23% of toddlers with good nutrition, 16.67% of toddlers with mothers who had primary school education, and 7.15% of toddlers with mothers who had a junior high school education. The percentage of the development of questionable language is higher in toddlers who have risk factors than in toddlers who don't have risk factors.
在幼儿发展阶段,即1-3岁,语言技能成为幼儿与周围环境互动交流过程中非常关键的一个方面。在这个时候,孩子们开始发展词汇,语言技能,理解指令,用单词表达自己。本研究旨在概述印度尼西亚苏邦Sagalaherang区Posyandu Anggrek Sukamandi幼儿语言技能的发展情况。本研究为描述性观察性研究。共有42名研究对象参与了本研究。用PDQ进行单因素分析以筛选语言技能。有语言发展问题的幼儿占7.14%。28.57%的营养不良幼儿、3.23%的营养良好幼儿、16.67%的母亲受过小学教育的幼儿、7.15%的母亲受过初中教育的幼儿出现语言发育不良。有风险因素的幼儿发展出问题语言的比例要高于没有风险因素的幼儿。
{"title":"Overview of the Development of Language Skills in Toddlers with Prescreening Developmental Questionnaire (PDQ) at Posyandu Anggrek Sukamandi, Sagalaherang District, Subang, Indonesia","authors":"Noventy Sutarman","doi":"10.37275/oaijmr.v3i4.321","DOIUrl":"https://doi.org/10.37275/oaijmr.v3i4.321","url":null,"abstract":"At the toddler development stage, namely 1-3 years old, language skills become a very crucial aspect in the process of interaction and communication with the surrounding environment. At this time, children begin to develop vocabulary, speech skills, understand instructions, and express themselves using words. This study aimed to provide an overview of the development of language skills in toddlers at Posyandu Anggrek Sukamandi, Sagalaherang District, Subang, Indonesia. This study was a descriptive observational study. A total of 42 research subjects participated in this study. Univariate analysis was carried out to screen language skills with the PDQ. Toddlers who experience questionable language development are 7.14%. Toddlers with adverse language development were found in 28.57% of toddlers with malnutrition and 3.23% of toddlers with good nutrition, 16.67% of toddlers with mothers who had primary school education, and 7.15% of toddlers with mothers who had a junior high school education. The percentage of the development of questionable language is higher in toddlers who have risk factors than in toddlers who don't have risk factors.","PeriodicalId":106715,"journal":{"name":"Open Access Indonesian Journal of Medical Reviews","volume":"108 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122564432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Relationship between Nutritional Status and Shortness of Breath in Children with Pneumonia at Mappi General Hospital, Indonesia 印尼马皮总医院肺炎患儿营养状况与呼吸短促的关系
Pub Date : 2023-06-27 DOI: 10.37275/oaijmr.v3i4.318
Naomi Deby, R. Lembang, Mikawati, R. Pratiwi
The relationship between nutritional status and shortness of breath in childhood pneumonia is an important concern in the management and management of this disease. Poor nutritional status in children can influence their immune system, making them more susceptible to infections such as pneumonia. This study aimed to determine the relationship between nutritional status and the incidence of shortness of breath in children with pneumonia at Mappi General Hospital, Indonesia. This study is a cross-sectional analytic observational study. A total of 49 research subjects were included in this study. Data analysis was carried out using SPSS using univariate and bivariate relationships between nutritional status and the incidence of shortness of breath in pneumonia patients. The majority of pneumonia patients with malnutrition experienced symptoms of shortness of breath compared to pneumonia patients with normal nutrition, p<0.05. There is a significant relationship between poor nutritional status and the incidence of shortness of breath in pediatric patients with pneumonia.
儿童肺炎的营养状况与呼吸短促之间的关系是该疾病管理和管理的一个重要问题。儿童营养不良会影响他们的免疫系统,使他们更容易感染肺炎等传染病。本研究旨在确定营养状况与印度尼西亚Mappi总医院肺炎患儿呼吸短促发生率之间的关系。本研究为横断面分析观察性研究。本研究共纳入49名研究对象。采用SPSS统计软件对营养状况与肺炎患者呼吸短促发生率之间的单因素和双因素关系进行数据分析。营养不良的肺炎患者与营养正常的肺炎患者相比,多数出现呼吸短促的症状,p<0.05。小儿肺炎患者营养状况不良与呼吸短促的发生率有显著关系。
{"title":"The Relationship between Nutritional Status and Shortness of Breath in Children with Pneumonia at Mappi General Hospital, Indonesia","authors":"Naomi Deby, R. Lembang, Mikawati, R. Pratiwi","doi":"10.37275/oaijmr.v3i4.318","DOIUrl":"https://doi.org/10.37275/oaijmr.v3i4.318","url":null,"abstract":"The relationship between nutritional status and shortness of breath in childhood pneumonia is an important concern in the management and management of this disease. Poor nutritional status in children can influence their immune system, making them more susceptible to infections such as pneumonia. This study aimed to determine the relationship between nutritional status and the incidence of shortness of breath in children with pneumonia at Mappi General Hospital, Indonesia. This study is a cross-sectional analytic observational study. A total of 49 research subjects were included in this study. Data analysis was carried out using SPSS using univariate and bivariate relationships between nutritional status and the incidence of shortness of breath in pneumonia patients. The majority of pneumonia patients with malnutrition experienced symptoms of shortness of breath compared to pneumonia patients with normal nutrition, p<0.05. There is a significant relationship between poor nutritional status and the incidence of shortness of breath in pediatric patients with pneumonia.","PeriodicalId":106715,"journal":{"name":"Open Access Indonesian Journal of Medical Reviews","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127957161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Awareness of Polycystic Ovarian Syndrome among Jordanian Females 约旦女性对多囊卵巢综合征的认识
Pub Date : 2023-06-23 DOI: 10.37275/oaijmr.v3i3.315
D. Barrouq, Zaineh Faisal, Rasheed Alazawa, Tareq Irshaidat
Many endocrine-related conditions have attracted the attention of medical societies worldwide. Many of them may have a serious impact on female re-productivity and overall health. Among them is the polycystic ovarian syndrome (PCOS). However, an early diagnosis is crucial in avoiding any potential complications. This study aimed at evaluating the awareness of PCOS among Jordanian females. The outcomes shall be implemented to improve public health through the various educational services, medical campaigns, and healthcare practitioners in Jordan and other societies. A cross-sectional study using a survey (questionnaires) was directed toward a sample of Jordanian females aged 18-40 years. The assessment of their knowledge and understanding included its signs, symptoms, and associated health risks. Thus, the collected data were subject to processing and statistical analysis. The majority of females (73.3%) were aware of the potentiality of PCOS, but the majority of the sample was not satisfactorily familiar with the signs and symptoms of the disease, and only 6% confirmed getting education directly from a doctor. The study outcome reveals that the current level of PCOS awareness among Jordanian females needs a comprehensive educational effort.
许多与内分泌有关的疾病引起了全世界医学界的注意。其中许多可能对女性的生殖能力和整体健康产生严重影响。其中包括多囊卵巢综合征(PCOS)。然而,早期诊断对于避免任何潜在的并发症至关重要。本研究旨在评估约旦女性对多囊卵巢综合征的认识。将实施这些成果,通过约旦和其他社会的各种教育服务、医疗运动和保健从业人员来改善公众健康。一项横断面研究使用调查(问卷)的样本是针对约旦女性年龄在18-40岁。对他们的知识和理解的评估包括其体征、症状和相关的健康风险。因此,对收集到的数据进行处理和统计分析。大多数女性(73.3%)意识到多囊卵巢综合征的可能性,但大多数样本对疾病的体征和症状并不熟悉,只有6%的人确认直接从医生那里得到了教育。研究结果表明,目前约旦女性对多囊卵巢综合征的认识水平需要全面的教育努力。
{"title":"Awareness of Polycystic Ovarian Syndrome among Jordanian Females","authors":"D. Barrouq, Zaineh Faisal, Rasheed Alazawa, Tareq Irshaidat","doi":"10.37275/oaijmr.v3i3.315","DOIUrl":"https://doi.org/10.37275/oaijmr.v3i3.315","url":null,"abstract":"Many endocrine-related conditions have attracted the attention of medical societies worldwide. Many of them may have a serious impact on female re-productivity and overall health. Among them is the polycystic ovarian syndrome (PCOS). However, an early diagnosis is crucial in avoiding any potential complications. This study aimed at evaluating the awareness of PCOS among Jordanian females. The outcomes shall be implemented to improve public health through the various educational services, medical campaigns, and healthcare practitioners in Jordan and other societies. A cross-sectional study using a survey (questionnaires) was directed toward a sample of Jordanian females aged 18-40 years. The assessment of their knowledge and understanding included its signs, symptoms, and associated health risks. Thus, the collected data were subject to processing and statistical analysis. The majority of females (73.3%) were aware of the potentiality of PCOS, but the majority of the sample was not satisfactorily familiar with the signs and symptoms of the disease, and only 6% confirmed getting education directly from a doctor. The study outcome reveals that the current level of PCOS awareness among Jordanian females needs a comprehensive educational effort.","PeriodicalId":106715,"journal":{"name":"Open Access Indonesian Journal of Medical Reviews","volume":"96 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116747908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effect of Vitamin D Supplementation in Psoriasis: A Systematic Literature Review 补充维生素D对银屑病的影响:系统文献综述
Pub Date : 2023-06-20 DOI: 10.37275/oaijmr.v3i3.317
Maria Ulva, Yenti Sukarida, Mery Lisa Pratiwi
One of the key factors in the development of psoriasis is inflammation. In people with psoriasis, the immune system mistakenly attacks healthy skin cells, causing them to grow too quickly. This leads to the buildup of dead skin cells on the surface of the skin. Vitamin D can help to reduce inflammation by suppressing the production of pro-inflammatory cytokines. This study aimed to conduct a systematic review to explore the potential of vitamin D supplementation in psoriasis. The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) regarding the potential of vitamin D supplementation in psoriasis. This study follows the preferred reporting items for systematic reviews and meta-analysis (PRISMA) recommendations. Vitamin D inhibits the inflammatory process in psoriasis by inhibiting the production of pro-inflammatory cytokines, activating anti-inflammatory, immune cells, and protecting cells from damage caused by inflammation.
银屑病发展的关键因素之一是炎症。牛皮癣患者的免疫系统会错误地攻击健康的皮肤细胞,导致它们生长过快。这会导致死皮细胞在皮肤表面堆积。维生素D可以通过抑制促炎细胞因子的产生来帮助减少炎症。本研究旨在进行系统综述,探讨补充维生素D治疗牛皮癣的潜力。在各种数据库(PubMed、Web of Sciences、EMBASE、Cochrane Libraries和Google Scholar)上进行文献检索,以了解补充维生素D治疗牛皮癣的可能性。本研究遵循系统评价和荟萃分析(PRISMA)推荐的首选报告项目。维生素D通过抑制促炎细胞因子的产生,激活抗炎、免疫细胞,保护细胞免受炎症引起的损伤,从而抑制银屑病的炎症过程。
{"title":"The Effect of Vitamin D Supplementation in Psoriasis: A Systematic Literature Review","authors":"Maria Ulva, Yenti Sukarida, Mery Lisa Pratiwi","doi":"10.37275/oaijmr.v3i3.317","DOIUrl":"https://doi.org/10.37275/oaijmr.v3i3.317","url":null,"abstract":"One of the key factors in the development of psoriasis is inflammation. In people with psoriasis, the immune system mistakenly attacks healthy skin cells, causing them to grow too quickly. This leads to the buildup of dead skin cells on the surface of the skin. Vitamin D can help to reduce inflammation by suppressing the production of pro-inflammatory cytokines. This study aimed to conduct a systematic review to explore the potential of vitamin D supplementation in psoriasis. The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) regarding the potential of vitamin D supplementation in psoriasis. This study follows the preferred reporting items for systematic reviews and meta-analysis (PRISMA) recommendations. Vitamin D inhibits the inflammatory process in psoriasis by inhibiting the production of pro-inflammatory cytokines, activating anti-inflammatory, immune cells, and protecting cells from damage caused by inflammation.","PeriodicalId":106715,"journal":{"name":"Open Access Indonesian Journal of Medical Reviews","volume":"145 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114417156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Potential of CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats), Gene Editing Technology, in the Treatment of Coronary Artery Disease: A Systematic Literature Review CRISPR(聚集规则间隔短回文重复序列)基因编辑技术在冠状动脉疾病治疗中的潜力:系统文献综述
Pub Date : 2023-06-20 DOI: 10.37275/oaijmr.v3i3.316
Hilda Mayasari, Winda Nestamer
The treatment of CAD depends on the severity of the disease and the individual's risk factors. There are a number of medications that can help to slow the progression of CAD and reduce the risk of complications. The treatments for CAD can have side effects, which can make it difficult for people to adhere to their treatment plan. The treatments for CAD can be expensive, which can make it difficult for people to afford them. This is especially true for people who do not have insurance. This study aimed to conduct a systematic review to explore the potential of CRISPR in CAD management. The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) regarding the potential of CRISPR in the treatment of coronary artery disease. This study follows the preferred reporting items for systematic reviews and meta-analysis (PRISMA) recommendations. CRISPR has great potential as a future therapeutic modality for coronary artery disease, where this technology is able to control various CAD risk factors and can trigger the formation of new blood vessels to overcome coronary artery blockade. However, this very potential technology still requires ethical concern studies in order to be able to maintain human sustainability.
CAD的治疗取决于疾病的严重程度和个人的危险因素。有许多药物可以帮助减缓冠心病的进展,降低并发症的风险。CAD的治疗可能有副作用,这可能使人们难以坚持他们的治疗计划。CAD的治疗可能很昂贵,这使得人们很难负担得起。对于那些没有保险的人来说尤其如此。本研究旨在进行系统综述,探讨CRISPR在CAD管理中的潜力。在各种数据库(PubMed、Web of Sciences、EMBASE、Cochrane Libraries和Google Scholar)上进行文献检索,以了解CRISPR在冠状动脉疾病治疗中的潜力。本研究遵循系统评价和荟萃分析(PRISMA)推荐的首选报告项目。CRISPR作为冠状动脉疾病的未来治疗方式具有很大的潜力,该技术能够控制各种CAD危险因素,并可以触发新血管的形成以克服冠状动脉阻塞。然而,这种非常有潜力的技术仍然需要伦理关注的研究,以便能够维持人类的可持续性。
{"title":"The Potential of CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats), Gene Editing Technology, in the Treatment of Coronary Artery Disease: A Systematic Literature Review","authors":"Hilda Mayasari, Winda Nestamer","doi":"10.37275/oaijmr.v3i3.316","DOIUrl":"https://doi.org/10.37275/oaijmr.v3i3.316","url":null,"abstract":"The treatment of CAD depends on the severity of the disease and the individual's risk factors. There are a number of medications that can help to slow the progression of CAD and reduce the risk of complications. The treatments for CAD can have side effects, which can make it difficult for people to adhere to their treatment plan. The treatments for CAD can be expensive, which can make it difficult for people to afford them. This is especially true for people who do not have insurance. This study aimed to conduct a systematic review to explore the potential of CRISPR in CAD management. The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) regarding the potential of CRISPR in the treatment of coronary artery disease. This study follows the preferred reporting items for systematic reviews and meta-analysis (PRISMA) recommendations. CRISPR has great potential as a future therapeutic modality for coronary artery disease, where this technology is able to control various CAD risk factors and can trigger the formation of new blood vessels to overcome coronary artery blockade. However, this very potential technology still requires ethical concern studies in order to be able to maintain human sustainability.","PeriodicalId":106715,"journal":{"name":"Open Access Indonesian Journal of Medical Reviews","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131572065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Role of Behavioral Planning Interventions in Maintaining Dental and Oral Health Behavior among Students in Yogyakarta, Indonesia 行为计划干预在维持牙齿和口腔健康行为在日惹,印度尼西亚的学生中的作用
Pub Date : 2023-06-02 DOI: 10.37275/oaijmr.v3i3.310
Rr Pipiet, Okti Kusumastiwi, Salsabila Krisnaputri
Various efforts and methods have been developed to increase individual awareness of maintaining oral health. Behavioral planning interventions differ from interventions or counseling, which generally only prioritize aspects of knowledge. The theory of planned behavior states that a behavior is not necessarily born from mere knowledge; there are contributions of other factors, such as the role of peer groups and beliefs, which play a role in triggering a behavior. This study aimed to evaluate the role of behavioral planning interventions in maintaining oral health behavior in adolescents. This study is a quasi-experimental study with a pre and post-test design approach. The research was conducted on new students at Universitas Muhammadiyah Yogyakarta, Indonesia. The inclusion criteria for participants were new students (less than six months studying in college), 18 years old, and willing to participate. Participants filled out the initial questionnaire as a pre-test to assess aspects of knowledge related to dental health. Then the subjects were given behavioral planning interventions by creating a group community using social media for all research subjects. The intervention process was carried out for three months. A post-test evaluation was conducted to assess the success of the intervention. Data analysis was carried out using the SPSS version 25 program. The results of this study indicate an improvement in scores related to personal attitude, subjective norms, perceived behavioral control, and behavior to maintain dental and oral health after conducting behavioral planning interventions (p <0.05). In conclusion, behavioral planning interventions help improve individual behavior in maintaining oral health in adolescents.
各种努力和方法已经发展,以提高个人的意识,保持口腔健康。行为规划干预不同于干预或咨询,后者通常只优先考虑知识的各个方面。计划行为理论指出,一种行为并不一定源于单纯的知识;还有其他因素的影响,如同伴群体和信仰的作用,在引发行为方面发挥作用。本研究旨在评估行为计划干预在维持青少年口腔健康行为中的作用。本研究为准实验研究,采用前后测试设计方法。这项研究是在印度尼西亚日惹穆罕默德大学(Universitas Muhammadiyah Yogyakarta)的新生中进行的。参与者的入选标准为新生(在大学学习时间少于6个月),年龄18岁,愿意参与。参与者填写了最初的调查问卷,作为评估与牙齿健康有关的知识方面的预测试。然后,通过使用社交媒体为所有研究对象创建群体社区,对受试者进行行为规划干预。干预过程进行了三个月。测试后进行评估,以评估干预的成功。数据分析使用SPSS 25版程序进行。本研究结果显示,实施行为计划干预后,患者在个人态度、主观规范、感知行为控制和维持口腔健康行为方面的得分均有改善(p <0.05)。综上所述,行为计划干预有助于改善青少年维护口腔健康的个体行为。
{"title":"The Role of Behavioral Planning Interventions in Maintaining Dental and Oral Health Behavior among Students in Yogyakarta, Indonesia","authors":"Rr Pipiet, Okti Kusumastiwi, Salsabila Krisnaputri","doi":"10.37275/oaijmr.v3i3.310","DOIUrl":"https://doi.org/10.37275/oaijmr.v3i3.310","url":null,"abstract":"Various efforts and methods have been developed to increase individual awareness of maintaining oral health. Behavioral planning interventions differ from interventions or counseling, which generally only prioritize aspects of knowledge. The theory of planned behavior states that a behavior is not necessarily born from mere knowledge; there are contributions of other factors, such as the role of peer groups and beliefs, which play a role in triggering a behavior. This study aimed to evaluate the role of behavioral planning interventions in maintaining oral health behavior in adolescents. This study is a quasi-experimental study with a pre and post-test design approach. The research was conducted on new students at Universitas Muhammadiyah Yogyakarta, Indonesia. The inclusion criteria for participants were new students (less than six months studying in college), 18 years old, and willing to participate. Participants filled out the initial questionnaire as a pre-test to assess aspects of knowledge related to dental health. Then the subjects were given behavioral planning interventions by creating a group community using social media for all research subjects. The intervention process was carried out for three months. A post-test evaluation was conducted to assess the success of the intervention. Data analysis was carried out using the SPSS version 25 program. The results of this study indicate an improvement in scores related to personal attitude, subjective norms, perceived behavioral control, and behavior to maintain dental and oral health after conducting behavioral planning interventions (p <0.05). In conclusion, behavioral planning interventions help improve individual behavior in maintaining oral health in adolescents.","PeriodicalId":106715,"journal":{"name":"Open Access Indonesian Journal of Medical Reviews","volume":"170 2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131509289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Overview of Toddler Height and Weight in Patients with Malnutrition at the Dukuh Kupang Health Center, Surabaya 在Dukuh Kupang健康中心,泗水儿童营养不良患者的身高和体重概述
Pub Date : 2023-05-29 DOI: 10.37275/oaijmr.v3i3.307
Nindy Kurniati Binti Sholihah, Akas Yekti Pulih Asih
Children do not get enough energy intake, so the body will use energy reserves in the form of fat and protein to maintain important body functions. This can cause weight loss in children, especially if the nutritional deficiency lasts for a long time. Overall, a child's height and weight are very important in assessing a child's nutritional status because both are good indicators of growth and development. If there are disturbances in the growth and development of children, then this can be a sign that the child has nutritional problems that need to be taken seriously. This study aimed to determine the relationship between height and weight with malnutrition in infants at the Dukuh Kupang Health Center area as a descriptive observational study. The data used in this study were height and weight data as well as the nutritional status of infants obtained from Health Centers in the Dukuh Kupang Health Center area. Regression analysis was performed to determine whether height and weight have a significant effect on the nutritional status of infants. The results showed that height and weight had a significant effect on the nutritional status of infants, with significant regression coefficient values for each variable. In addition, the ANOVA test also shows that the regression model used is significant. These results can be used as a basis for improving public health programs related to the problem of malnutrition in toddlers in the Dukuh Kupang Health Center area.
儿童没有得到足够的能量摄入,所以身体会以脂肪和蛋白质的形式使用能量储备来维持重要的身体功能。这可能会导致儿童体重下降,特别是如果营养缺乏持续很长时间。总的来说,儿童的身高和体重对于评估儿童的营养状况非常重要,因为它们都是生长发育的良好指标。如果孩子的生长发育出现障碍,那么这可能是孩子有营养问题的迹象,需要认真对待。本研究旨在确定身高和体重与Dukuh Kupang健康中心地区婴儿营养不良之间的关系,作为一项描述性观察研究。本研究使用的数据是从Dukuh Kupang健康中心地区的健康中心获得的婴儿的身高和体重数据以及营养状况。通过回归分析确定身高和体重对婴儿营养状况是否有显著影响。结果表明,身高和体重对婴儿营养状况有显著影响,各变量回归系数值均显著。此外,ANOVA检验也表明所使用的回归模型是显著的。这些结果可以作为改善与Dukuh Kupang保健中心地区幼儿营养不良问题有关的公共卫生方案的基础。
{"title":"Overview of Toddler Height and Weight in Patients with Malnutrition at the Dukuh Kupang Health Center, Surabaya","authors":"Nindy Kurniati Binti Sholihah, Akas Yekti Pulih Asih","doi":"10.37275/oaijmr.v3i3.307","DOIUrl":"https://doi.org/10.37275/oaijmr.v3i3.307","url":null,"abstract":"Children do not get enough energy intake, so the body will use energy reserves in the form of fat and protein to maintain important body functions. This can cause weight loss in children, especially if the nutritional deficiency lasts for a long time. Overall, a child's height and weight are very important in assessing a child's nutritional status because both are good indicators of growth and development. If there are disturbances in the growth and development of children, then this can be a sign that the child has nutritional problems that need to be taken seriously. This study aimed to determine the relationship between height and weight with malnutrition in infants at the Dukuh Kupang Health Center area as a descriptive observational study. The data used in this study were height and weight data as well as the nutritional status of infants obtained from Health Centers in the Dukuh Kupang Health Center area. Regression analysis was performed to determine whether height and weight have a significant effect on the nutritional status of infants. The results showed that height and weight had a significant effect on the nutritional status of infants, with significant regression coefficient values for each variable. In addition, the ANOVA test also shows that the regression model used is significant. These results can be used as a basis for improving public health programs related to the problem of malnutrition in toddlers in the Dukuh Kupang Health Center area.","PeriodicalId":106715,"journal":{"name":"Open Access Indonesian Journal of Medical Reviews","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114545016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inflammatory Response Plays a Role in Innate Immunity: A Narrative Literature Review 炎症反应在先天免疫中的作用:叙述性文献综述
Pub Date : 2023-05-08 DOI: 10.37275/oaijmr.v3i2.301
Rara Inggarsih, R. Hidayat, Article Info
The inflammatory response is the rapid initiation and interplay of humoral (dissolved in the blood) and cellular systems designed to limit the degree of tissue damage, destroy infectious microorganisms, initiate an adaptive immune response, and initiate the healing process. This review aimed to comprehensively describe the role of the inflammatory response in innate immunity. Three key plasma protein systems are essential for an effective inflammatory response. These are the complement system, clotting system, and kinin system. Although each system has a unique role in inflammation, they also share many similarities. Each system consists of several proteins in the blood. To prevent activation in unnecessary situations, each protein is normally in an inactive form. Some proteins are enzymes that circulate in an inactive form as proenzymes. Each system contains several proteins that can be activated at the start of inflammation. Cells of the innate and acquired immune systems are recruited and activated by biochemical mediators produced at sites of cell damage. These molecules originate from destroyed or damaged cells, contaminating microbes, activation of plasma protein systems, or secretion by other cells of the innate or acquired immune system. Activation may result in the cell acquiring a function essential for the inflammatory response or inducing the release of additional cellular products that promote inflammation, or both. In conclusion, inflammatory cells and various protein systems (complement, kinin, and clotting), together with the substances they produce, act at the site of tissue injury to limit the extent of damage, kill microorganisms, and remove debris in preparation for healing: tissue regeneration or repair.
炎症反应是体液(溶解在血液中)和细胞系统的快速启动和相互作用,旨在限制组织损伤的程度,破坏感染性微生物,启动适应性免疫反应,并启动愈合过程。这篇综述旨在全面描述炎症反应在先天免疫中的作用。三个关键的血浆蛋白系统对于有效的炎症反应是必不可少的。它们是补体系统、凝血系统和激蛋白系统。尽管每个系统在炎症中都有独特的作用,但它们也有许多相似之处。每个系统由血液中的几种蛋白质组成。为了防止在不必要的情况下激活,每种蛋白质通常处于非活性形式。有些蛋白质是酶,以无活性形式循环,如原酶。每个系统都包含几种可以在炎症开始时被激活的蛋白质。先天免疫系统和获得性免疫系统的细胞被细胞损伤部位产生的生化介质招募和激活。这些分子来源于被破坏或受损的细胞,污染微生物,激活血浆蛋白系统,或由先天或获得性免疫系统的其他细胞分泌。激活可能导致细胞获得炎症反应所必需的功能或诱导释放促进炎症的额外细胞产物,或两者兼而有之。总之,炎症细胞和各种蛋白质系统(补体、激肽和凝血蛋白)及其产生的物质,在组织损伤部位起作用,限制损伤程度,杀死微生物,清除碎片,为愈合做准备:组织再生或修复。
{"title":"Inflammatory Response Plays a Role in Innate Immunity: A Narrative Literature Review","authors":"Rara Inggarsih, R. Hidayat, Article Info","doi":"10.37275/oaijmr.v3i2.301","DOIUrl":"https://doi.org/10.37275/oaijmr.v3i2.301","url":null,"abstract":"The inflammatory response is the rapid initiation and interplay of humoral (dissolved in the blood) and cellular systems designed to limit the degree of tissue damage, destroy infectious microorganisms, initiate an adaptive immune response, and initiate the healing process. This review aimed to comprehensively describe the role of the inflammatory response in innate immunity. Three key plasma protein systems are essential for an effective inflammatory response. These are the complement system, clotting system, and kinin system. Although each system has a unique role in inflammation, they also share many similarities. Each system consists of several proteins in the blood. To prevent activation in unnecessary situations, each protein is normally in an inactive form. Some proteins are enzymes that circulate in an inactive form as proenzymes. Each system contains several proteins that can be activated at the start of inflammation. Cells of the innate and acquired immune systems are recruited and activated by biochemical mediators produced at sites of cell damage. These molecules originate from destroyed or damaged cells, contaminating microbes, activation of plasma protein systems, or secretion by other cells of the innate or acquired immune system. Activation may result in the cell acquiring a function essential for the inflammatory response or inducing the release of additional cellular products that promote inflammation, or both. In conclusion, inflammatory cells and various protein systems (complement, kinin, and clotting), together with the substances they produce, act at the site of tissue injury to limit the extent of damage, kill microorganisms, and remove debris in preparation for healing: tissue regeneration or repair.","PeriodicalId":106715,"journal":{"name":"Open Access Indonesian Journal of Medical Reviews","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116836679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Open Access Indonesian Journal of Medical Reviews
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1