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Severe Acidemia Without Bicarbonate: Increased Organ Support and Post-ICU Mortality During a Drug Shortage. 无碳酸氢盐的严重酸血症:药物短缺期间器官支持和icu后死亡率增加。
IF 6 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2026-02-01 Epub Date: 2026-02-03 DOI: 10.1097/CCM.0000000000006911
Tsai Ling Ting, Yuan-Ti Lee
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引用次数: 0
Concern With Long-Term Effects of Early Neuromuscular Electrical Stimulation With Mobilization in Critically Ill Patients. 危重病人早期神经肌肉电刺激与活动的长期影响。
IF 6 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2026-02-01 Epub Date: 2026-02-03 DOI: 10.1097/CCM.0000000000006959
Taichi Matsuo, Shunsuke Taito
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引用次数: 0
The authors reply. 作者回答说。
IF 6 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2026-02-01 Epub Date: 2026-02-03 DOI: 10.1097/CCM.0000000000006987
Yoshitaka Aoki, Satoshi Naruse, Yoshiki Nakajima
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引用次数: 0
The authors reply. 作者回答说。
IF 6 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2026-02-01 Epub Date: 2026-02-03 DOI: 10.1097/CCM.0000000000006984
Christopher M Horvat, Aimee Boeltz, Chenell Donadee
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引用次数: 0
The Role of Perceived Urgency and Barriers in Using Emergency Medical Care for Sepsis: A German-Wide, Representative Survey Using Case Vignettes. 感知的紧迫性和障碍在使用紧急医疗护理败血症中的作用:一项德国范围内的代表性调查,使用案例小插图。
IF 6 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2026-02-01 Epub Date: 2025-12-03 DOI: 10.1097/CCM.0000000000006967
Sebastian Born, Norman Rose, Silke Piedmont, Daniel Schwarzkopf, Mathias W Pletz, Wiltrud Abels, Konrad Reinhart, Carolin Fleischmann-Struzek

Objectives: Delays in emergency medical care (EMC) can increase sepsis mortality. Sepsis symptoms, however, are less known in the public compared with signs of stroke and myocardial infarction. Using case vignettes, we investigated the decision to seek EMC in sepsis-related compared with other emergencies.

Design: Cross-sectional survey.

Settings and subjects: A representative nationwide survey was conducted in December 2023 among 1013 persons in Germany.

Interventions: None.

Measurements and main results: A standardized questionnaire was administered via face-to-face interviews to assess perceived urgency, the tendency to seek EMC, sepsis knowledge, and barriers to EMC utilization. Multiple regression analyses were conducted to identify predictors for the perceived urgency and the tendency to seek EMC. Across ten case vignettes, the perceived urgency was lower for sepsis-related (mean = 3.93, sd = 0.64) than for nonsepsis-related emergencies (mean=4.15, sd = 0.67). In sepsis-related vignettes, the immediate EMC option ("Call emergency medical services or go to the emergency department [ED] immediately") was chosen by 18.3-43.2% of respondents, compared with 20.1-71.9% in nonsepsis-related vignettes. Even when situations were rated as very urgent, EMC use was less likely for sepsis-related emergencies (35%) than for nonsepsis-related emergencies (17%). In regression analyses, sepsis knowledge was the only predictor of perceived urgency, and perceived urgency was the strongest predictor of EMC use. The likelihood of EMC use in sepsis-related emergencies was 14.9 percentage points lower ( p < 0.01) than in nonsepsis-related emergencies; "long waiting times in the ED" was the only significant barrier for EMC use.

Conclusions: Compared with nonsepsis emergencies, sepsis-related emergencies are perceived as less urgent and less often lead to EMC use, even if the level of perceived urgency is the same. As the perceived urgency is associated with sepsis knowledge, this underlines the need to increase efforts to improve sepsis knowledge and the awareness that sepsis requires timely emergency care in the general public.

目的:紧急医疗护理(EMC)延误可增加败血症死亡率。然而,与中风和心肌梗死的症状相比,败血症的症状在公众中鲜为人知。通过个案调查,我们调查了与脓毒症相关的紧急情况相比,寻求EMC的决定。设计:横断面调查。背景和对象:2023年12月,在德国对1013人进行了一项具有代表性的全国性调查。干预措施:没有。测量和主要结果:通过面对面访谈进行标准化问卷调查,以评估感知的紧迫性、寻求EMC的倾向、败血症知识和使用EMC的障碍。进行多元回归分析以确定感知紧迫性和寻求EMC倾向的预测因子。在10个病例调查中,与败血症相关的紧急情况(平均= 3.93,sd = 0.64)比与非败血症相关的紧急情况(平均=4.15,sd = 0.67)感知的紧迫性更低。在败血症相关的小插曲中,18.3-43.2%的受访者选择了立即EMC选项(“立即呼叫紧急医疗服务或前往急诊科[ED]”),而在非败血症相关的小插曲中,这一比例为20.1-71.9%。即使情况被评为非常紧急,与败血症相关的紧急情况(35%)比与非败血症相关的紧急情况(17%)更少使用EMC。在回归分析中,脓毒症知识是感知紧迫性的唯一预测因子,而感知紧迫性是EMC使用的最强预测因子。在败血症相关急诊中使用EMC的可能性比在非败血症相关急诊中低14.9个百分点(p < 0.01);“在急诊室等待时间过长”是使用EMC的唯一重大障碍。结论:与非脓毒症紧急情况相比,即使感知到的紧急程度相同,脓毒症相关的紧急情况也被认为不那么紧急,并且很少导致使用EMC。由于感知到的紧迫性与脓毒症知识相关,这强调了需要加大努力,提高脓毒症知识和意识,脓毒症需要及时的紧急护理在广大公众。
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引用次数: 0
Characteristics and Effectiveness of Nurse-Led Family Communication Interventions in the ICU: A Systematic Review and Meta-Analysis. ICU中护士主导的家庭沟通干预的特点和效果:系统回顾和meta分析。
IF 6 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2026-02-01 Epub Date: 2025-11-14 DOI: 10.1097/CCM.0000000000006952
ZhiRu Li, FangYan Lu, Martha Abshire Saylor, JingYun Wu, Nancy R Reynolds, JiaLei Wang, Hyeyoung Hwang, HuaFen Wang, Jennifer Wenzel

Objective: To determine the characteristics and effectiveness of nurse-led family communication interventions in the ICU.

Data sources: PubMed, Web of Science, PsychInfo, CINAHL, Embase, Cochrane Library, and relevant article citations from January 1995 to July 2025.

Study selection: We included randomized controlled trials (RCTs) and quasi-experimental studies evaluating nurse-led family communication interventions in adult ICUs.

Data extraction: Two independent reviewers assessed evidence levels and risk of bias using the Cochrane tool and the Joanna Briggs Institute's Critical Appraisal Tools. Data were synthesized according to the Preferred Reporting Items for Systematic Reviews guidelines, and interventions were summarized with the Template for Intervention Description and Replication Checklist.

Data synthesis: Seven RCTs and seven quasi-experimental studies were included. The most common nurse-family communication model was an in-person, structured, and dynamically tailored intervention during the patient's ICU stay. Nurses played five core roles: information delivery and clarification, emotional support, family assessment, family meeting facilitation, and transitional support. Bedside ICU nurses led information delivery and multidimensional family assessments. Internal research nurses handled information clarification, structured needs assessment, and family meeting coordination. External research nurses focused on family meeting support, structured emotional support, and transitional care. Although the interventions may improve communication quality (standardized mean differences [SMD] = 0.26) and reduce hospital length of stay (LOS) (mean differences [MD] = -3.87 d), they appear to have limited effects on psychologic distress, satisfaction, ICU LOS, or mortality; they may also increase family meeting frequency/duration and lower overall costs.

Conclusions: The conclusions of our systematic review are limited by considerable heterogeneity in intervention intensity, implementer profiles, and adaptation descriptions. Future interventions should define optimal dosage and outline best practices for evidence-based intervention tailoring and implementation. Healthcare institutions should integrate specialized nursing roles, such as training bedside nurses or establishing dedicated communication facilitators. This approach may leverage nurses' expertise to enhance communication quality and improve outcomes.

目的:探讨护士主导的ICU家庭沟通干预的特点及效果。数据来源:PubMed, Web of Science, PsychInfo, CINAHL, Embase, Cochrane Library, 1995年1月至2025年7月的相关文章引文。研究选择:我们纳入了随机对照试验(rct)和准实验研究,评估护士主导的成人icu家庭沟通干预措施。数据提取:两名独立审稿人使用Cochrane工具和Joanna Briggs研究所的关键评估工具评估证据水平和偏倚风险。根据“系统评价首选报告项目”指南对数据进行综合,并根据“干预措施描述和复制清单模板”对干预措施进行总结。资料综合:纳入7项随机对照试验和7项准实验研究。最常见的护士-家庭沟通模式是在患者ICU住院期间进行面对面、结构化和动态定制的干预。护士扮演了五个核心角色:信息传递和澄清、情感支持、家庭评估、家庭会议促进和过渡支持。床边ICU护士主导信息传递和多维家庭评估。内部研究护士处理信息澄清、结构化需求评估和家庭会议协调。外部研究护士侧重于家庭会议支持、结构化情感支持和过渡护理。虽然干预措施可以改善沟通质量(标准化平均差异[SMD] = 0.26)并缩短住院时间(平均差异[MD] = -3.87 d),但它们对心理困扰、满意度、ICU LOS或死亡率的影响有限;它们还可能增加家庭会议的频率/持续时间,并降低总体成本。结论:我们系统综述的结论受到干预强度、实施者简介和适应描述的相当大的异质性的限制。未来的干预措施应确定最佳剂量,并概述以证据为基础的干预措施调整和实施的最佳做法。医疗机构应整合专业护理角色,如培训床边护士或建立专门的沟通促进者。这种方法可以利用护士的专业知识来提高沟通质量和改善结果。
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引用次数: 0
Extending the Observational Medical Outcomes Partnership (OMOP) Common Data Model for Critical Care Medicine: A Framework for Standardizing Complex ICU Data Using the Society of Critical Care Medicine's Critical Care Data Dictionary (C2D2). 扩展观察性医疗结果伙伴关系(OMOP)重症监护医学通用数据模型:使用重症监护医学学会重症监护数据字典(C2D2)标准化复杂ICU数据的框架。
IF 6 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2026-02-01 Epub Date: 2025-11-21 DOI: 10.1097/CCM.0000000000006969
Meredith C B Adams, Robert W Hurley, Karsten Bartels, Matthew L Perkins, Cody Hudson, Umit Topaloglu, J Perren Cobb, Karin Reuter-Rice, Jacqueline C Stocking, Ashish K Khanna

Objectives: To evaluate the compatibility of the Society of Critical Care Medicine's (SCCM) Critical Care Data Dictionary (C2D2) with the Observational Medical Outcomes Partnership (OMOP) Common Data Model (CDM) and initiate a set of steps extending OMOP to accommodate specialized critical care data elements.

Design: Systematic analysis and mapping study using a three-tiered semantic matching approach to demonstrate technical feasibility and identify fundamental challenges in critical care data standardization.

Setting: Critical care medicine informatics research environment.

Subjects: The SCCM's C2D2 elements.

Interventions: None.

Measurements and main results: We evaluated the compatibility of C2D2 clinical variables with the OMOP CDM using a three-tier classification system (full match, partial match, and no match). Our analysis of 226 C2D2 elements revealed that 49.6% of concepts had full OMOP equivalents, 46.4% required modification, and 4.0% had no suitable mapping. Key incompatibilities were identified in ventilator parameters, composite scoring systems, and advanced organ support documentation. A large language model-based semantic matching system yielded a precision of 59.5%, recall of 87.0%, and F1 score of 70.7% at an optimized similarity threshold of 0.90. These findings highlight the need to harmonize data standardization approaches within the field of critical care, including how to handle concept stacking within single variables, age-specific criteria, and specialized constructs that were curated through the SCCM Delphi process, but reveal an OMOP mapping incompatibility or missing variables.

Conclusions: Extending the OMOP CDM for critical care is technically feasible and requires targeted modifications to accommodate composite scores, temporal precision, and specialized critical care concepts as well as the resources needed to support this build. The community acutely faces crucial decisions about whether to pursue OMOP integration, adapt the C2D2 for version 2.0 compatibility, work toward OMOP vocabulary inclusion through Observational Health Data Sciences and Informatics processes, or collaborate with electronic health record vendors for native critical care standards support. These decisions require balancing technical feasibility with long-term sustainability and maintenance considerations.

目的:评估重症医学学会(SCCM)重症监护数据字典(C2D2)与观察性医疗结果合作伙伴关系(OMOP)公共数据模型(CDM)的兼容性,并启动一系列扩展OMOP以适应专门的重症监护数据元素的步骤。设计:使用三层语义匹配方法进行系统分析和映射研究,以证明技术可行性并确定重症监护数据标准化中的基本挑战。环境:危重医学信息学研究环境。研究对象:SCCM的C2D2元素。干预措施:没有。测量和主要结果:我们使用三层分类系统(完全匹配、部分匹配和不匹配)评估C2D2临床变量与OMOP CDM的兼容性。我们对226个C2D2元素的分析表明,49.6%的概念具有完整的OMOP等同物,46.4%需要修改,4.0%没有合适的映射。在呼吸机参数、复合评分系统和高级器官支持文件中确定了关键的不兼容性。基于大型语言模型的语义匹配系统在优化的相似度阈值为0.90时,准确率为59.5%,召回率为87.0%,F1得分为70.7%。这些发现强调了在重症监护领域协调数据标准化方法的必要性,包括如何处理单变量、年龄特定标准和通过SCCM德尔菲过程整理的专门结构中的概念堆叠,但揭示了OMOP映射不兼容或缺失变量。结论:将OMOP CDM扩展到重症监护在技术上是可行的,但需要有针对性的修改,以适应复合评分、时间精度、专门的重症监护概念以及支持该构建所需的资源。社区迫切地面临着关键的决定,是追求OMOP集成,使C2D2适应2.0版本的兼容性,通过观察健康数据科学和信息学过程努力实现OMOP词汇的包含,还是与电子健康记录供应商合作以支持本地重症监护标准。这些决策需要平衡技术可行性与长期可持续性和维护方面的考虑。
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引用次数: 0
Haloperidol in Intensive Care Delirium: A Trade-Off Between Survival and Functional Recovery. 氟哌啶醇治疗重症谵妄:生存与功能恢复之间的权衡。
IF 6 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2026-02-01 Epub Date: 2026-02-03 DOI: 10.1097/CCM.0000000000006908
Shiuan-Chih Chen, Chung-Hsin Yeh
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引用次数: 0
Collider Bias: The Forgotten Bias in Observational Studies. 对撞机偏差:观察性研究中被遗忘的偏差。
IF 6 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2026-02-01 Epub Date: 2026-02-03 DOI: 10.1097/CCM.0000000000006957
Bruno A M P Besen, Larissa Bianchini, Daryl Jones
{"title":"Collider Bias: The Forgotten Bias in Observational Studies.","authors":"Bruno A M P Besen, Larissa Bianchini, Daryl Jones","doi":"10.1097/CCM.0000000000006957","DOIUrl":"https://doi.org/10.1097/CCM.0000000000006957","url":null,"abstract":"","PeriodicalId":10765,"journal":{"name":"Critical Care Medicine","volume":"54 2","pages":"388-389"},"PeriodicalIF":6.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146112667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The authors reply. 作者回答说。
IF 6 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2026-02-01 Epub Date: 2026-02-03 DOI: 10.1097/CCM.0000000000006986
Amanda Y Leong, Daniel J Niven
{"title":"The authors reply.","authors":"Amanda Y Leong, Daniel J Niven","doi":"10.1097/CCM.0000000000006986","DOIUrl":"https://doi.org/10.1097/CCM.0000000000006986","url":null,"abstract":"","PeriodicalId":10765,"journal":{"name":"Critical Care Medicine","volume":"54 2","pages":"378-379"},"PeriodicalIF":6.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146112714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Critical Care Medicine
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