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Factors affecting the fate of nanoencapsulates post administration. 影响纳米胶囊用药后命运的因素。
IF 7.3 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2024-11-01 Epub Date: 2023-08-21 DOI: 10.1080/10408398.2023.2245462
D Subhasri, M Maria Leena, J A Moses, C Anandharamakrishnan

Nanoencapsulation has found numerous applications in the food and nutraceutical industries. Micro and nanoencapsulated forms of bioactives have proven benefits in terms of stability, release, and performance in the body. However, the encapsulated ingredient is often subjected to a wide range of processing conditions and this is followed by storage, consumption, and transit along the gastrointestinal tract. A strong understanding of the fate of nanoencapsulates in the biological system is mandatory as it provides valuable insights for ingredient selection, formulation, and application. In addition to their efficacy, there is also the need to assess the safety of ingested nanoencapsulates. Given the rising research and commercial focus of this subject, this review provides a strong focus on their interaction factors and mechanisms, highlighting their prospective biological fate. This review also covers various approaches to studying the fate of nanoencapsulates in the body. Also, with emphasis on the overall scope, the need for a new advanced integrated common methodology to evaluate the fate of nanoencapsulates post-administration is discussed.

纳米胶囊技术在食品和保健品行业应用广泛。事实证明,微胶囊和纳米胶囊形式的生物活性物质在稳定性、释放和在体内的表现方面都有好处。然而,封装成分通常要经受各种加工条件的考验,随后还要经过储存、食用和胃肠道转运等过程。必须深入了解纳米胶囊在生物系统中的命运,因为它能为成分的选择、配制和应用提供有价值的见解。除了功效之外,还需要评估摄入纳米胶囊的安全性。鉴于对这一主题的研究和商业关注日益增多,本综述将重点关注它们的相互作用因素和机制,突出它们的预期生物命运。本综述还涵盖了研究纳米胶囊在体内归宿的各种方法。此外,在强调总体范围的同时,还讨论了采用新的先进综合通用方法评估纳米胶囊用药后转归的必要性。
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引用次数: 0
An update of aurones: food resource, health benefit, biosynthesis and application. 金合欢的最新进展:食物资源、健康益处、生物合成和应用。
IF 7.3 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2024-11-01 Epub Date: 2023-08-21 DOI: 10.1080/10408398.2023.2248244
Jiali Yang, Zhengjiao Gao, Zhiqian Yu, Yu Hou, Dingtao Tang, Huiling Yan, Fuwang Wu, Sui Kiat Chang, Yonggui Pan, Yueming Jiang, Zhengke Zhang, Bao Yang

Aurones are a subclass of active flavonoids characterized with a scaffold of 2-benzylidene-3(2H)-benzofuranone. This type of chemicals are widely distributed in fruit, vegetable and flower, and contribute to human health. In this review, we summarize the natural aurones isolated from dietary plants. Their positive effects on immunomodulation, antioxidation, cancer prevention as well as maintaining the health status of cardiovascular, nervous system and liver organs are highlighted. The biosynthesis strategies of plant-derived aurones are elaborated to provide solutions for their limited natural abundance. The potential application of natural aurones in food coloration are also discussed. This paper combines the up-to-date information and gives a full image of dietary aurones.

枳壳酮是活性黄酮的一个亚类,以 2-亚苄基-3(2H)-苯并呋喃酮为支架。这类化学物质广泛分布于水果、蔬菜和花卉中,有助于人类健康。在这篇综述中,我们总结了从膳食植物中分离出来的天然呋喃酮。重点介绍了它们在免疫调节、抗氧化、防癌以及维持心血管、神经系统和肝脏器官健康状况方面的积极作用。详细阐述了植物醛酮的生物合成策略,为有限的天然醛酮资源提供了解决方案。此外,还讨论了天然醛酮在食品着色方面的潜在应用。本文综合了最新信息,全面介绍了膳食中的urones。
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引用次数: 0
Nano techniques: an updated review focused on anthocyanin stability. 纳米技术:以花青素稳定性为重点的最新综述。
IF 7.3 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2024-11-01 Epub Date: 2023-08-13 DOI: 10.1080/10408398.2023.2245893
Tisong Liang, Pu Jing, Jian He

Anthocyanins (ACNs) are one of the subgroups of flavonoids and getting intensive attraction due to the nutritional values. However, their application of ACNs is limited due to their poor stability and bioavailability. Accordingly, nanoencapsulation has been developed to enhance its stability and bio-efficacy. This review focuses on the nano-technique applications of delivery systems that be used for ACNs stabilization, with an emphasis on physicochemical stability and health benefits. ACNs incorporated with delivery systems in forms of nano-particles and fibrils can achieve advanced functions, such as improved stability, enhanced bioavailability, and controlled release. Also, the toxicological evaluation of nano delivery systems is summarized. Additionally, this review summarizes the challenges and suggests the further perspectives for the further application of ACNs delivery systems in food and medical fields.

花青素(ACNs)是类黄酮的一个亚类,因其营养价值而备受青睐。然而,由于花青素的稳定性和生物利用度较差,其应用受到了限制。因此,人们开发了纳米封装技术来提高其稳定性和生物有效性。本综述重点介绍可用于稳定 ACNs 的纳米技术应用,重点是理化稳定性和对健康的益处。将 ACN 与纳米颗粒和纤维等形式的递送系统结合在一起,可实现先进的功能,如提高稳定性、增强生物利用度和控制释放。本综述还总结了纳米给药系统的毒理学评估。此外,本综述还总结了 ACNs 给药系统在食品和医疗领域进一步应用所面临的挑战,并提出了进一步的展望。
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引用次数: 0
The impact of climate change on Omega-3 long-chain polyunsaturated fatty acids in bivalves. 气候变化对双壳类动物体内 Omega-3 长链多不饱和脂肪酸的影响。
IF 7.3 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2024-11-01 Epub Date: 2023-08-09 DOI: 10.1080/10408398.2023.2242943
Karsoon Tan, Julian Ransangan, Kianann Tan, Kit-Leong Cheong

Omega-3 long-chain polyunsaturated fatty acids (n-3 LC-PUFA) have many health benefits to human. Increasing evidence have shown that climate change reduces the availability of plankton n-3 LC-PUFA to primary consumers which potentially reduces the availability of n-3 LC-PUFA to human. Since marine bivalves are an important source of n-3 LC-PUFA for human beings, and bivalve aquaculture completely depends on phytoplankton in ambient water as food, it is important to understand the impact of climate change on the lipid nutritional quality of bivalves. In this study, fatty acid profile of different bivalves (mussels, oysters, clams, scallops and cockles) from different regions (tropical, subtropical and temperate) and time (before 1990, 1991-1995, 1996-2000, 2001-2005, 2006-2010, 2011-2015, 2016-2020) were extracted from published literature to calculate various lipid nutritional quality indicators. The results of this study revealed that the effects of global warming and declines in aragonite saturation state on the lipid content and lipid indices of bivalves are highly dependent on the geographical region and bivalves. In general, global warming has the largest negative impact on the lipid content and indices of temperate bivalves, including decreasing the PUFA/SFA, EPA + DHA and n-3/n-6. However, global warming has a much smaller negative impact on lipid content and lipid indices in other regions. The declines of aragonite saturation state in seawater promotes the accumulation of lipid content in tropical and subtropical bivalves, but it compromised the PUFA/SFA, EPA + DHA and n-3/n-6 of bivalves in all regions. The findings of this study not only fill the knowledge gap of the impact of climate change on the lipid nutritional quality of bivalves, but also provide guidance for the establishment of bivalve aquaculture and fisheries management plans to mitigate the impact of climate change.

奥米加-3 长链多不饱和脂肪酸(n-3 LC-PUFA)对人类健康有许多益处。越来越多的证据表明,气候变化减少了浮游生物初级消费者可获得的 n-3 LC-PUFA,从而可能减少人类可获得的 n-3 LC-PUFA。由于海洋双壳贝类是人类获取 n-3 LC-PUFA 的重要来源,而双壳贝类养殖完全依赖环境水中的浮游植物作为食物,因此了解气候变化对双壳贝类脂质营养质量的影响非常重要。本研究从已发表的文献中提取了不同地区(热带、亚热带和温带)、不同时间(1990 年前、1991-1995 年、1996-2000 年、2001-2005 年、2006-2010 年、2011-2015 年、2016-2020 年)不同双壳类动物(贻贝、牡蛎、蛤蜊、扇贝和蚶子)的脂肪酸谱,计算出各种脂质营养质量指标。研究结果表明,全球变暖和文石饱和度下降对双壳贝类脂质含量和脂质指数的影响与地理区域和双壳贝类有很大关系。总体而言,全球变暖对温带双壳类动物脂质含量和脂质指数的负面影响最大,包括降低 PUFA/SFA、EPA + DHA 和 n-3/n-6。然而,全球变暖对其他地区脂质含量和脂质指数的负面影响要小得多。海水中文石饱和度的下降促进了热带和亚热带双壳类动物脂质含量的积累,但却损害了所有地区双壳类动物的 PUFA/SFA、EPA + DHA 和 n-3/n-6。本研究的发现不仅填补了气候变化对双壳贝类脂质营养质量影响的知识空白,而且为制定双壳贝类养殖和渔业管理计划以减轻气候变化的影响提供了指导。
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引用次数: 0
Bioactive milk peptides: an updated comprehensive overview and database. 生物活性牛奶肽:最新综合概述和数据库。
IF 7.3 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2024-11-01 Epub Date: 2023-07-28 DOI: 10.1080/10408398.2023.2240396
Søren Drud-Heydary Nielsen, Ningjian Liang, Harith Rathish, Bum Jin Kim, Jiraporn Lueangsakulthai, Jeewon Koh, Yunyao Qu, Hans-Jörg Schulz, David C Dallas

Partial digestion of milk proteins leads to the formation of numerous bioactive peptides. Previously, our research team thoroughly examined the decades of existing literature on milk bioactive peptides across species to construct the milk bioactive peptide database (MBPDB). Herein, we provide a comprehensive update to the data within the MBPDB and a review of the current state of research for each functional category from in vitro to animal and clinical studies, including angiotensin-converting enzyme (ACE)-inhibitory, antimicrobial, antioxidant, dipeptidyl peptidase (DPP)-IV inhibitory, opioid, anti-inflammatory, immunomodulatory, calcium absorption and bone health and anticancer activity. This information will help drive future research on the bioactivities of milk peptides.

对牛奶蛋白质进行部分消化会产生大量生物活性肽。在此之前,我们的研究团队深入研究了数十年来关于不同物种牛奶生物活性肽的现有文献,构建了牛奶生物活性肽数据库(MBPDB)。在此,我们将全面更新 MBPDB 中的数据,并回顾从体外研究到动物和临床研究等各个功能类别的研究现状,包括血管紧张素转换酶 (ACE) 抑制、抗菌、抗氧化、二肽基肽酶 (DPP)-IV 抑制、阿片类、抗炎、免疫调节、钙吸收和骨骼健康以及抗癌活性。这些信息将有助于推动未来对牛奶肽生物活性的研究。
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引用次数: 0
A review on the hydration properties of dietary fibers derived from food waste and their interactions with other ingredients: opportunities and challenges for their application in the food industry. 综述从食物垃圾中提取的膳食纤维的水合特性及其与其他成分的相互作用:它们在食品工业中应用的机遇与挑战。
IF 7.3 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2024-11-01 Epub Date: 2023-08-11 DOI: 10.1080/10408398.2023.2243510
Ahasanul Karim, Zarifeh Raji, Youssef Habibi, Seddik Khalloufi

Dietary fiber (DF) significantly affects the quality attributes of food matrices. Depending on its chemical composition, molecular structure, and degree of hydration, the behavior of DF may differ. Numerous reports confirm that incorporating DF derived from food waste into food products has significant effects on textural, sensory, rheological, and antimicrobial properties. Additionally, the characteristics of DF, modification techniques (chemical, enzymatic, mechanical, thermal), and processing conditions (temperature, pH, ionic strength), as well as the presence of other components, can profoundly affect the functionalities of DF. This review aims to describe the interactions between DF and water, focusing on the effects of free water, freezing-bound water, and unfreezing-bound water on the hydration capacity of both soluble and insoluble DF. The review also explores how the structural, functional, and environmental properties of DF contribute to its hydration capacity. It becomes evident that the interactions between DF and water, and their effects on the rheological properties of food matrices, are complex and multifaceted subjects, offering both opportunities and challenges for further exploration. Utilizing DF extracted from food waste exhibits promise as a sustainable and viable strategy for the food industry to create nutritious and high-value-added products, while concurrently reducing reliance on primary virgin resources.

膳食纤维(DF)对食品基质的质量属性有很大影响。根据其化学成分、分子结构和水合程度的不同,膳食纤维的行为也会有所不同。大量报告证实,将从食物垃圾中提取的 DF 添加到食品中会对质地、感官、流变学和抗菌特性产生显著影响。此外,DF 的特性、改性技术(化学、酶、机械、热)、加工条件(温度、pH 值、离子强度)以及其他成分的存在都会对 DF 的功能产生深远影响。本综述旨在描述 DF 与水之间的相互作用,重点关注自由水、冷冻结合水和非冷冻结合水对可溶和不溶 DF 水合能力的影响。综述还探讨了 DF 的结构、功能和环境特性如何影响其水合能力。显而易见,DF 与水之间的相互作用及其对食品基质流变特性的影响是复杂而多面的课题,为进一步探索提供了机遇和挑战。利用从食物垃圾中提取的 DF,有望成为食品工业创造营养丰富的高附加值产品的可持续可行策略,同时减少对原生资源的依赖。
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引用次数: 0
Valorization of potato by-products as a source of plant proteins: novel extraction techniques and potential applications. 马铃薯副产品作为植物蛋白来源的增值:新型提取技术和潜在应用。
IF 7.3 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2024-10-30 DOI: 10.1080/10408398.2024.2419534
Zhipeng Hu, Xianglu Zhu, Gaoya Dong, Joncer Naibaho, Shay Hannon, Da-Wen Sun, Brijesh K Tiwari

The potential of potato by-products as a protein source presents an exciting opportunity to explore new methods and technologies to extract, enhance, and incorporate this valuable protein source into a variety of food products. This article reviews the progress in research related to potato and other tuber plant protein extraction technology. It also explores some conventional and novel techniques for plant protein extraction that may be applicable to tuber protein extraction. For extraction from solid matter, conventional methods such as acid-base extraction with heat assistance often mean a waste of energy, solvent, and destruction of protein structure. Enzyme-assisted, ultrasound-assisted, and pulsed electric field extraction have their own advantages as novel processing methods. For liquid by-products of tuber plants, precipitation, membrane filtration and chromatography are applied to extract proteins. By combining protein extraction with various biomass extraction methods, every part of the potatoes can be fully utilized, minimizing waste. This approach offers the opportunity to optimize the utilization of all potatoes components, reduce waste, generate additional revenue streams and ultimately increase the sustainability and effectiveness of the process.

马铃薯副产品作为蛋白质来源的潜力为探索新方法和新技术以提取、提高并将这一宝贵的蛋白质来源纳入各种食品提供了一个令人兴奋的机会。本文回顾了与马铃薯和其他块茎植物蛋白提取技术有关的研究进展。文章还探讨了一些可能适用于块茎植物蛋白提取的常规和新型植物蛋白提取技术。对于从固体物质中提取蛋白质,传统方法(如加热辅助的酸碱提取法)往往意味着能源、溶剂的浪费和蛋白质结构的破坏。作为新型加工方法,酶辅助、超声波辅助和脉冲电场萃取各有优势。对于块茎植物的液体副产品,可采用沉淀法、膜过滤法和色谱法提取蛋白质。通过将蛋白质提取与各种生物质提取方法相结合,可以充分利用马铃薯的每一部分,最大限度地减少浪费。这种方法为优化马铃薯所有成分的利用、减少浪费、创造额外收入流以及最终提高工艺的可持续性和有效性提供了机会。
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引用次数: 0
Exploring the potential of MFG-E8 in neurodegenerative diseases. 探索 MFG-E8 在神经退行性疾病中的潜力。
IF 7.3 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2024-10-28 DOI: 10.1080/10408398.2024.2417800
Dan Li, Wang Rongchun, Weihong Lu, Ying Ma

Milk fat globule-epidermal growth factor 8 (MFG-E8) is a multifunctional glycoprotein regulating intercellular interactions in various biological and pathological processes. This review summarizes the effects and mechanisms of MFG-E8 in neurodegenerative diseases (NDDs), emphasizing its roles in inflammation, apoptosis, and oxidative stress. In this review, will also explore the potential of MFG-E8 as a diagnostic biomarker and its therapeutic applications in neurodegenerative disorders. Recent studies have revealed intriguing characteristics of using MFG-E8 as a potential drug for treating various brain disorders. While the discovery, origin, expression, and physiological functions of MFG-E8 in various organs and tissues are well defined, its role in the brain remains less understood. This is particularly true for NDDs, indicating unmet medical needs. Elucidating its role in the brain could position MFG-E8 as a potential treatment for NDDs.

牛奶脂肪球-表皮生长因子8(MFG-E8)是一种多功能糖蛋白,在各种生物和病理过程中调节细胞间的相互作用。本综述总结了 MFG-E8 在神经退行性疾病(NDDs)中的作用和机制,强调了它在炎症、细胞凋亡和氧化应激中的作用。本综述还将探讨 MFG-E8 作为诊断生物标志物的潜力及其在神经退行性疾病中的治疗应用。最近的研究揭示了将 MFG-E8 用作治疗各种脑部疾病的潜在药物的令人感兴趣的特点。虽然MFG-E8在各种器官和组织中的发现、起源、表达和生理功能都已明确,但其在大脑中的作用仍不甚明了。这一点在非传染性疾病中尤为明显,表明医疗需求尚未得到满足。阐明MFG-E8在大脑中的作用可将其定位为治疗NDDs的潜在疗法。
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引用次数: 0
Synthesis, characterization and application of microbial pigments in foods as natural colors. 作为天然色素的微生物色素在食品中的合成、表征和应用。
IF 7.3 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2024-10-28 DOI: 10.1080/10408398.2024.2417802
Gopinath Mummaleti, Toshifumi Udo, Anand Mohan, Fanbin Kong

Colorants have played a crucial role in various applications, particularly in food processing, with natural sources such as mineral ores, plants, insects, and animals being commonly used. However, the nineteenth century saw the development of synthetic dyes, which replaced these natural colorants. In recent years, there has been a growing demand for natural products, driving an increased interest in natural colorants. Microbial pigments have emerged as promising sources of natural pigments due to their numerous health benefits. They can be produced in large quantities rapidly and from more affordable substrates, making them economically attractive. This review focuses on the current advancements in the low-cost synthesis of microbial pigments, exploring their biological activities and commercial applications. Microbial pigments offer a sustainable and economically viable alternative to natural and synthetic colorants, meeting the growing demand for natural products. These pigments are relatively nontoxic and exhibit significant health benefits, making them suitable for a wide range of applications. As interest in natural products continues to rise, microbial pigments hold great potential in shaping the future of colorant production across various sectors.

着色剂在各种应用中,尤其是在食品加工中发挥着至关重要的作用,天然来源的着色剂,如矿石、植物、昆虫和动物等,都是常用的着色剂。然而,十九世纪合成染料的发展取代了这些天然着色剂。近年来,人们对天然产品的需求日益增长,从而推动了对天然着色剂的兴趣。微生物色素因其对健康的诸多益处而成为前景广阔的天然色素来源。微生物色素可以用更经济的基质快速大量生产,因此在经济上很有吸引力。本综述重点介绍目前在低成本合成微生物色素方面取得的进展,探讨其生物活性和商业应用。微生物颜料为天然和合成着色剂提供了一种可持续的、经济上可行的替代品,满足了人们对天然产品日益增长的需求。这些颜料相对无毒,并具有显著的健康益处,适合广泛的应用。随着人们对天然产品的兴趣不断增加,微生物颜料在塑造各行各业着色剂生产的未来方面具有巨大潜力。
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引用次数: 0
Opportunities and challenges of ultrasonic diagnostic techniques for plant-based food monitoring: principle, machine system, and application strategies. 用于植物性食品监测的超声波诊断技术的机遇与挑战:原理、机器系统和应用策略。
IF 7.3 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2024-10-25 DOI: 10.1080/10408398.2024.2418891
Jing Yan, Yingling Zhang, Zibin Jiao, Lifan Song, Zhijun Wang, Qing Zhang, Yaowen Liu, Wen Qin

Plant-based food consumption has increased substantially owing to its positive effects on human and global health. However, ensuring the quality and safety of plant-based foods remains a challenge. Diagnostic ultrasonic technology is widely used for rapid and nondestructive determination owing to its ability to penetrate optically opaque materials, strong directivity, rapid detection capabilities, low equipment costs, and ease of operation. This review provides a comprehensive understanding of diagnostic ultrasonic technology by summarizing the principles of food characterization, factors that influence detection accuracy and methods to mitigate their impact, composition of ultrasonic machine systems, and application of diagnostic ultrasound for monitoring plant-based foods. The detection principle of ultrasonic technology is based on empirical equations that establish a relationship between the ultrasonic and physicochemical indicators of food. To improve the detection accuracy, a compensation mechanism for the temperature and pressure should be established, measurement distances should be set in the far-field region, and liquid samples should be degassed. Furthermore, the sample platform design and the choice of detection mode depend on the nature of the food. Combining ultrasonic technology with machine learning techniques presents promising prospects for real-time process monitoring in the food and beverage industries.

由于植物性食品对人类和全球健康的积极影响,植物性食品的消费量大幅增加。然而,确保植物性食品的质量和安全仍然是一项挑战。超声波诊断技术具有穿透光学不透明材料的能力、强指向性、快速检测能力、设备成本低和操作简便等特点,因此被广泛用于快速和无损检测。本综述通过总结食品表征原理、影响检测精度的因素和减轻其影响的方法、超声波机器系统的组成以及超声波诊断技术在植物性食品监测中的应用,全面介绍超声波诊断技术。超声波技术的检测原理是基于经验方程,建立超声波与食品理化指标之间的关系。为提高检测精度,应建立温度和压力补偿机制,在远场区域设置测量距离,并对液体样品进行脱气处理。此外,样品平台的设计和检测模式的选择也取决于食品的性质。将超声波技术与机器学习技术相结合,为食品和饮料行业的实时过程监控带来了广阔的前景。
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引用次数: 0
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Critical reviews in food science and nutrition
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