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Candida in COVID-19: Gut-Lung Axis, Dysbiosis, and Infections 2019冠状病毒病中的念珠菌:肠-肺轴、生态失调和感染
Q3 Medicine Pub Date : 2023-10-17 DOI: 10.1007/s12281-023-00476-y
Milena Kordalewska, David S. Perlin
Abstract Purpose of Review This review discusses the connections between the gut-lung axis, gut and respiratory tract dysbiosis, and Candida bloodstream, oral, and respiratory infections in COVID-19 patients. Recent Findings COVID-19–related dysfunction in the intestinal barrier together with gut and lung dysbiosis played an important role in disease pathophysiology, which affected host immune homeostasis giving rise to prominent systemic and respiratory bacterial and fungal infections. Higher incidence of Candida bloodstream infections driven by accumulation of “classic” risk factors in severely ill COVID-19 patients was noted. Moreover, numerous C. auris outbreaks, characterized by high clonality of the strains, were reported from all around the world. Unlike other Candida species, C. auris colonization and infection cases most likely resulted from nosocomial transmission. Summary Infections due to Candida species in severely ill COVID-19 patients reflected the overall immune dysregulation and were largely driven by gut and respiratory tract dysbiosis.
本文综述了COVID-19患者肠-肺轴、肠道和呼吸道生态失调以及念珠菌血流、口腔和呼吸道感染之间的关系。新冠肺炎相关肠道屏障功能障碍与肠道和肺部生态失调在疾病病理生理中发挥重要作用,影响宿主免疫稳态,引起突出的全身和呼吸道细菌和真菌感染。报告指出,在COVID-19重症患者中,由于“经典”风险因素的积累,念珠菌血流感染的发生率较高。此外,世界各地报告了以菌株高克隆性为特征的许多金黄色葡萄球菌暴发。与其他念珠菌不同,耳念珠菌的定植和感染病例很可能是由医院传播引起的。COVID-19重症患者念珠菌感染反映了整体免疫失调,主要由肠道和呼吸道生态失调驱动。
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引用次数: 0
Emerging Challenges in Diagnosis and Treatment of Invasive Fungal Infections: Addressing the Impact of COVID-19 and New Pathogens 侵袭性真菌感染诊断和治疗中的新挑战:应对COVID-19和新病原体的影响
Q3 Medicine Pub Date : 2023-09-21 DOI: 10.1007/s12281-023-00475-z
Ali Ahmadi, Bahareh Bashardoust, Mahsa Abdorahimi, Selva Aminizadeh, Mohammadreza Salehi, Sadegh Khodavaisy
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引用次数: 0
Tinea Nigra in Children 儿童黑体病
Q3 Medicine Pub Date : 2023-09-11 DOI: 10.1007/s12281-023-00473-1
Norma Olivia de la O-Escamilla, Dulce Melissa Martínez–Téllez, Miguel Ángel Sánchez-Romero, Elizabeth Esther Cortés-Salazar, Mirna Eréndira Toledo-Bahena, Carlos Alfredo Mena-Cedillos, Sonia Toussaint–Caire, Marcela Salazar–García, Adriana Valencia-Herrera, Alexandro Bonifaz
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引用次数: 0
Antifungal Prophylaxis in the Era of Targeted Chemotherapy for Acute Myelogenous Leukemia 急性髓性白血病靶向化疗时代的抗真菌预防
IF 1.4 Q3 Medicine Pub Date : 2023-07-27 DOI: 10.1007/s12281-023-00474-0
R. Lewis, M. Stanzani
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引用次数: 0
Respiratory Fungal Infections in Cystic Fibrosis: Diagnostic and Therapeutic Challenges 囊性纤维化的呼吸道真菌感染:诊断和治疗的挑战
IF 1.4 Q3 Medicine Pub Date : 2023-07-27 DOI: 10.1007/s12281-023-00467-z
Schwarz, Mainz, Romanowska, Rosseau, Schuette, Martin ‐ Souto, Ramirez ‐ Garcia, Eschenhagen
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引用次数: 0
A Scoping Review of the Changing Epidemiology and Risk Factors of Endogenous Candida Ocular Infections 内源性念珠菌眼部感染流行病学变化及危险因素的综述
IF 1.4 Q3 Medicine Pub Date : 2023-07-26 DOI: 10.1007/s12281-023-00468-y
Z. Pek, J. Bork
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引用次数: 0
Onychomycosis Caused by Fusarium Species: a Review 镰刀菌引起的甲真菌病研究进展
IF 1.4 Q3 Medicine Pub Date : 2023-07-10 DOI: 10.1007/s12281-023-00472-2
J. Rodríguez, Julio Roberto Hernández-Juárez, E. Corona-Rodarte, V. Muñoz‐Estrada
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引用次数: 0
Can There Be a Relationship Between Oral Candidiasis and Candidemia in ICU Patients? ICU患者口腔念珠菌病与念珠菌血症是否有关系?
IF 1.4 Q3 Medicine Pub Date : 2023-06-14 DOI: 10.1007/s12281-023-00470-4
Dalviany Taques Ferreira, Priscila Vieira da Silva, Hélio Chagas Chaves de Oliveira Junior, Kellyth Andrade Pereira Rocha, D. R. Da Silva, Nayla de Souza Pitangui, Janaína de Cássia Orlandi Sardi
{"title":"Can There Be a Relationship Between Oral Candidiasis and Candidemia in ICU Patients?","authors":"Dalviany Taques Ferreira, Priscila Vieira da Silva, Hélio Chagas Chaves de Oliveira Junior, Kellyth Andrade Pereira Rocha, D. R. Da Silva, Nayla de Souza Pitangui, Janaína de Cássia Orlandi Sardi","doi":"10.1007/s12281-023-00470-4","DOIUrl":"https://doi.org/10.1007/s12281-023-00470-4","url":null,"abstract":"","PeriodicalId":10813,"journal":{"name":"Current Fungal Infection Reports","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42537493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Maximizing Yield and Speed of Fungal Pathogen Identification with Molecular Testing Performed Directly on Patient Specimens 直接对患者标本进行分子检测,最大限度地提高真菌病原体鉴定的产量和速度
IF 1.4 Q3 Medicine Pub Date : 2023-06-08 DOI: 10.1007/s12281-023-00471-3
J. Lieberman, L. Bourassa
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引用次数: 0
Epidemiology and Prevalence of Azole-Resistant Aspergillus fumigatus: What Is Our Understanding of the Situation? 耐唑烟曲霉的流行病学和流行率:我们对这种情况的理解是什么?
IF 1.4 Q3 Medicine Pub Date : 2023-05-29 DOI: 10.1007/s12281-023-00469-x
N. Wiederhold
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引用次数: 0
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Current Fungal Infection Reports
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