Pub Date : 2021-10-13DOI: 10.1007/s40135-021-00278-w
Ethan Adre, R. Tonk
{"title":"Positive and Negative Dysphotopsias: Causes, Prevention, and Best Strategies for Treatment","authors":"Ethan Adre, R. Tonk","doi":"10.1007/s40135-021-00278-w","DOIUrl":"https://doi.org/10.1007/s40135-021-00278-w","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"9 1","pages":"117 - 126"},"PeriodicalIF":0.9,"publicationDate":"2021-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45211890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-10-08DOI: 10.1007/s40135-021-00276-y
L. Roisman, J. Rossetto, R. Goldhardt
{"title":"Autoimmune Retinopathy, Testing, and Its Controversies","authors":"L. Roisman, J. Rossetto, R. Goldhardt","doi":"10.1007/s40135-021-00276-y","DOIUrl":"https://doi.org/10.1007/s40135-021-00276-y","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"9 1","pages":"178 - 183"},"PeriodicalIF":0.9,"publicationDate":"2021-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48841981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-10-01DOI: 10.1007/s40135-021-00273-1
Michael J Gale, R. Kinast, F. Sanchez, S. Mansberger
{"title":"Adherence With Glaucoma Medications: Barriers to Success and Prospects for Improvement","authors":"Michael J Gale, R. Kinast, F. Sanchez, S. Mansberger","doi":"10.1007/s40135-021-00273-1","DOIUrl":"https://doi.org/10.1007/s40135-021-00273-1","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"9 1","pages":"184 - 189"},"PeriodicalIF":0.9,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43924211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Purpose: a)Confocal microscopy and aethesiometry have allowed clinicians to assess the structural and functional integrity of corneal nerves in health and disease. This review summarizes literature on nerves in dry eye disease (DED) and discusses how this data can be applied to DED diagnosis and treatment.
Recent findings: b)Subjects with DED have a heterogenous symptom and sign profile along with variability in nerve structure and function. Most studies have reported lower nerve density and sensitivity in aqueous tear deficiency, while findings are more inconsistent for other DED subtypes. Examining nerve status, along with profiling symptoms and signs of disease, can help categorize subjects into disease phenotypes (structural and functional patterns) that exist under the umbrella of DED. This, in turn, can guide therapeutic decision-making.
Summary: c)Due to the heterogeneity in symptoms and signs of DED, corneal nerve evaluations can be valuable for categorizing individuals into disease sub-types and for guiding clinical decision making.
{"title":"How Should Corneal Nerves be Incorporated Into the Diagnosis and Management of Dry Eye?","authors":"Sneh Patel, Divy Mehra, Kimberly Cabrera, Anat Galor","doi":"10.1007/s40135-021-00268-y","DOIUrl":"https://doi.org/10.1007/s40135-021-00268-y","url":null,"abstract":"<p><strong>Purpose: </strong>a)Confocal microscopy and aethesiometry have allowed clinicians to assess the structural and functional integrity of corneal nerves in health and disease. This review summarizes literature on nerves in dry eye disease (DED) and discusses how this data can be applied to DED diagnosis and treatment.</p><p><strong>Recent findings: </strong>b)Subjects with DED have a heterogenous symptom and sign profile along with variability in nerve structure and function. Most studies have reported lower nerve density and sensitivity in aqueous tear deficiency, while findings are more inconsistent for other DED subtypes. Examining nerve status, along with profiling symptoms and signs of disease, can help categorize subjects into disease phenotypes (structural and functional patterns) that exist under the umbrella of DED. This, in turn, can guide therapeutic decision-making.</p><p><strong>Summary: </strong>c)Due to the heterogeneity in symptoms and signs of DED, corneal nerve evaluations can be valuable for categorizing individuals into disease sub-types and for guiding clinical decision making.</p>","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"9 3","pages":"65-76"},"PeriodicalIF":0.9,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-021-00268-y","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39827374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-08-05DOI: 10.1007/s40135-021-00272-2
M. Di Nicola, B. Williams
{"title":"Current Indications for Photodynamic Therapy in Retina and Ocular Oncology","authors":"M. Di Nicola, B. Williams","doi":"10.1007/s40135-021-00272-2","DOIUrl":"https://doi.org/10.1007/s40135-021-00272-2","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"9 1","pages":"107-116"},"PeriodicalIF":0.9,"publicationDate":"2021-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42659218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-29DOI: 10.1007/s40135-021-00270-4
J. H. Tran, L. Pasquale
{"title":"A Comparison of Genomic Advances in Exfoliation Syndrome and Primary Open-Angle Glaucoma","authors":"J. H. Tran, L. Pasquale","doi":"10.1007/s40135-021-00270-4","DOIUrl":"https://doi.org/10.1007/s40135-021-00270-4","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"9 1","pages":"96 - 106"},"PeriodicalIF":0.9,"publicationDate":"2021-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-021-00270-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43337283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-01Epub Date: 2021-05-18DOI: 10.1007/s40135-021-00265-1
Osmel P Alvarez, Anat Galor, Ghada AlBayyat, Carol L Karp
Purpose of review: To discuss recent studies of imaging modalities for ocular surface pathologies.
Recent findings: Novel micro-ocular coherence tomography technology can produce high-resolution images of corneal cellular and nervous structures. Ocular coherence tomography angiography can aid in detecting early stage limbal stem cell deficiency. Several studies used in vivo confocal microscopy to evaluate corneal nerve metrics and morphology.
Summary: The applications of anterior segment optical coherence tomography, anterior segment optical coherence tomography angiography, ultrasound biomicroscopy, and in vivo confocal microscopy are useful technologies for imaging the ocular surface. Several studies have used artificial intelligence in combination with imaging technologies to create reliable and effective systems to detect and visualize ocular surface pathologies. AS OCT continues to be a key imaging tool and future development of μOCT technology may further enhance its utility.
综述目的：讨论有关眼表病变成像模式的最新研究：新型微型眼相干断层扫描技术可生成角膜细胞和神经结构的高分辨率图像。眼相干断层血管造影术有助于检测早期角膜缘干细胞缺乏症。几项研究利用体内共聚焦显微镜评估角膜神经指标和形态。摘要：眼前节光学相干断层扫描、眼前节光学相干断层血管造影、超声生物显微镜和体内共聚焦显微镜的应用是眼表成像的有用技术。有几项研究将人工智能与成像技术相结合，创建了可靠有效的系统来检测和观察眼表病变。AS OCT 仍是一种重要的成像工具，μOCT 技术的未来发展可能会进一步提高其实用性。
{"title":"Update on imaging modalities for ocular surface pathologies.","authors":"Osmel P Alvarez, Anat Galor, Ghada AlBayyat, Carol L Karp","doi":"10.1007/s40135-021-00265-1","DOIUrl":"10.1007/s40135-021-00265-1","url":null,"abstract":"<p><strong>Purpose of review: </strong>To discuss recent studies of imaging modalities for ocular surface pathologies.</p><p><strong>Recent findings: </strong>Novel micro-ocular coherence tomography technology can produce high-resolution images of corneal cellular and nervous structures. Ocular coherence tomography angiography can aid in detecting early stage limbal stem cell deficiency. Several studies used <i>in vivo</i> confocal microscopy to evaluate corneal nerve metrics and morphology.</p><p><strong>Summary: </strong>The applications of anterior segment optical coherence tomography, anterior segment optical coherence tomography angiography, ultrasound biomicroscopy, and <i>in vivo</i> confocal microscopy are useful technologies for imaging the ocular surface. Several studies have used artificial intelligence in combination with imaging technologies to create reliable and effective systems to detect and visualize ocular surface pathologies. AS OCT continues to be a key imaging tool and future development of μOCT technology may further enhance its utility.</p>","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"9 2","pages":"39-47"},"PeriodicalIF":0.9,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455836/pdf/nihms-1787847.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33461892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-01DOI: 10.1007/s40135-021-00264-2
Y. Kam, David A. Ramirez, Jennifer J. Ling, M. Greiner, Christopher S. Sáles
{"title":"Performing DMEK with Other Surgical Procedures: Staged vs. Combined Approaches in Straightforward Cases","authors":"Y. Kam, David A. Ramirez, Jennifer J. Ling, M. Greiner, Christopher S. Sáles","doi":"10.1007/s40135-021-00264-2","DOIUrl":"https://doi.org/10.1007/s40135-021-00264-2","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"9 1","pages":"57 - 64"},"PeriodicalIF":0.9,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-021-00264-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44002917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-17DOI: 10.1007/s40135-021-00267-z
Brandon VanderZee, B. Shafer, John P Berdahl
{"title":"Intracranial Pressure and Its Relationship to Glaucoma","authors":"Brandon VanderZee, B. Shafer, John P Berdahl","doi":"10.1007/s40135-021-00267-z","DOIUrl":"https://doi.org/10.1007/s40135-021-00267-z","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"9 1","pages":"83 - 87"},"PeriodicalIF":0.9,"publicationDate":"2021-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-021-00267-z","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43911171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-03-15DOI: 10.1007/s40135-021-00266-0
Arianna A. Tovar, Alfonso L. Sabater
{"title":"Autologous Blood Products: When, Where, and How?","authors":"Arianna A. Tovar, Alfonso L. Sabater","doi":"10.1007/s40135-021-00266-0","DOIUrl":"https://doi.org/10.1007/s40135-021-00266-0","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"9 1","pages":"48 - 56"},"PeriodicalIF":0.9,"publicationDate":"2021-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-021-00266-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49018439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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