Pub Date : 2021-06-29DOI: 10.1007/s40135-021-00270-4
J. H. Tran, L. Pasquale
{"title":"A Comparison of Genomic Advances in Exfoliation Syndrome and Primary Open-Angle Glaucoma","authors":"J. H. Tran, L. Pasquale","doi":"10.1007/s40135-021-00270-4","DOIUrl":"https://doi.org/10.1007/s40135-021-00270-4","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"9 1","pages":"96 - 106"},"PeriodicalIF":0.9,"publicationDate":"2021-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-021-00270-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43337283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-01Epub Date: 2021-05-18DOI: 10.1007/s40135-021-00265-1
Osmel P Alvarez, Anat Galor, Ghada AlBayyat, Carol L Karp
Purpose of review: To discuss recent studies of imaging modalities for ocular surface pathologies.
Recent findings: Novel micro-ocular coherence tomography technology can produce high-resolution images of corneal cellular and nervous structures. Ocular coherence tomography angiography can aid in detecting early stage limbal stem cell deficiency. Several studies used in vivo confocal microscopy to evaluate corneal nerve metrics and morphology.
Summary: The applications of anterior segment optical coherence tomography, anterior segment optical coherence tomography angiography, ultrasound biomicroscopy, and in vivo confocal microscopy are useful technologies for imaging the ocular surface. Several studies have used artificial intelligence in combination with imaging technologies to create reliable and effective systems to detect and visualize ocular surface pathologies. AS OCT continues to be a key imaging tool and future development of μOCT technology may further enhance its utility.
综述目的：讨论有关眼表病变成像模式的最新研究：新型微型眼相干断层扫描技术可生成角膜细胞和神经结构的高分辨率图像。眼相干断层血管造影术有助于检测早期角膜缘干细胞缺乏症。几项研究利用体内共聚焦显微镜评估角膜神经指标和形态。摘要：眼前节光学相干断层扫描、眼前节光学相干断层血管造影、超声生物显微镜和体内共聚焦显微镜的应用是眼表成像的有用技术。有几项研究将人工智能与成像技术相结合，创建了可靠有效的系统来检测和观察眼表病变。AS OCT 仍是一种重要的成像工具，μOCT 技术的未来发展可能会进一步提高其实用性。
{"title":"Update on imaging modalities for ocular surface pathologies.","authors":"Osmel P Alvarez, Anat Galor, Ghada AlBayyat, Carol L Karp","doi":"10.1007/s40135-021-00265-1","DOIUrl":"10.1007/s40135-021-00265-1","url":null,"abstract":"<p><strong>Purpose of review: </strong>To discuss recent studies of imaging modalities for ocular surface pathologies.</p><p><strong>Recent findings: </strong>Novel micro-ocular coherence tomography technology can produce high-resolution images of corneal cellular and nervous structures. Ocular coherence tomography angiography can aid in detecting early stage limbal stem cell deficiency. Several studies used <i>in vivo</i> confocal microscopy to evaluate corneal nerve metrics and morphology.</p><p><strong>Summary: </strong>The applications of anterior segment optical coherence tomography, anterior segment optical coherence tomography angiography, ultrasound biomicroscopy, and <i>in vivo</i> confocal microscopy are useful technologies for imaging the ocular surface. Several studies have used artificial intelligence in combination with imaging technologies to create reliable and effective systems to detect and visualize ocular surface pathologies. AS OCT continues to be a key imaging tool and future development of μOCT technology may further enhance its utility.</p>","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"9 2","pages":"39-47"},"PeriodicalIF":0.9,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455836/pdf/nihms-1787847.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33461892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-01DOI: 10.1007/s40135-021-00264-2
Y. Kam, David A. Ramirez, Jennifer J. Ling, M. Greiner, Christopher S. Sáles
{"title":"Performing DMEK with Other Surgical Procedures: Staged vs. Combined Approaches in Straightforward Cases","authors":"Y. Kam, David A. Ramirez, Jennifer J. Ling, M. Greiner, Christopher S. Sáles","doi":"10.1007/s40135-021-00264-2","DOIUrl":"https://doi.org/10.1007/s40135-021-00264-2","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"9 1","pages":"57 - 64"},"PeriodicalIF":0.9,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-021-00264-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44002917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-17DOI: 10.1007/s40135-021-00267-z
Brandon VanderZee, B. Shafer, John P Berdahl
{"title":"Intracranial Pressure and Its Relationship to Glaucoma","authors":"Brandon VanderZee, B. Shafer, John P Berdahl","doi":"10.1007/s40135-021-00267-z","DOIUrl":"https://doi.org/10.1007/s40135-021-00267-z","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"9 1","pages":"83 - 87"},"PeriodicalIF":0.9,"publicationDate":"2021-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-021-00267-z","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43911171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-03-15DOI: 10.1007/s40135-021-00266-0
Arianna A. Tovar, Alfonso L. Sabater
{"title":"Autologous Blood Products: When, Where, and How?","authors":"Arianna A. Tovar, Alfonso L. Sabater","doi":"10.1007/s40135-021-00266-0","DOIUrl":"https://doi.org/10.1007/s40135-021-00266-0","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"9 1","pages":"48 - 56"},"PeriodicalIF":0.9,"publicationDate":"2021-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-021-00266-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49018439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-03-01Epub Date: 2021-02-20DOI: 10.1007/s40135-020-00260-y
Umangi Patel, Carol L Karp, Sander R Dubovy
Purpose of review: To review and update the latest findings in diagnosis and management of ocular surface squamous neoplasia (OSSN).
Recent findings: OSSN is the most common anterior segment neoplastic disease process. Several ocular surface imaging techniques have been developed for the early diagnosis and management of clinical and subclinical ocular surface squamous neoplasia, including high-resolution optical coherence tomography (HR-OCT), in vivo confocal microscopy, and ultrasound biomicroscopy. Treatment modalities include both surgical and medical management, with a recent trend towards primary and adjunctive pharmacotherapy.
Summary: There is increasing use of HR-OCT for the diagnosis and monitoring of clinical and subclinical OSSN lesions. Topical pharmacotherapy agents, including interferon α-2b, 5-fluorouracil, and mitomycin C, have demonstrable efficacy in the treatment of OSSN and their use may be dictated based upon tumor factors, patient factors, cost, and side effect profile. Both surgical excision and adjunctive topical medications have excellent success, with the favored treatment method trending towards topical pharmacotherapy as primary therapy.
{"title":"Update on the Management of Ocular Surface Squamous Neoplasia.","authors":"Umangi Patel, Carol L Karp, Sander R Dubovy","doi":"10.1007/s40135-020-00260-y","DOIUrl":"https://doi.org/10.1007/s40135-020-00260-y","url":null,"abstract":"<p><strong>Purpose of review: </strong>To review and update the latest findings in diagnosis and management of ocular surface squamous neoplasia (OSSN).</p><p><strong>Recent findings: </strong>OSSN is the most common anterior segment neoplastic disease process. Several ocular surface imaging techniques have been developed for the early diagnosis and management of clinical and subclinical ocular surface squamous neoplasia, including high-resolution optical coherence tomography (HR-OCT), in vivo confocal microscopy, and ultrasound biomicroscopy. Treatment modalities include both surgical and medical management, with a recent trend towards primary and adjunctive pharmacotherapy.</p><p><strong>Summary: </strong>There is increasing use of HR-OCT for the diagnosis and monitoring of clinical and subclinical OSSN lesions. Topical pharmacotherapy agents, including interferon α-2b, 5-fluorouracil, and mitomycin C, have demonstrable efficacy in the treatment of OSSN and their use may be dictated based upon tumor factors, patient factors, cost, and side effect profile. Both surgical excision and adjunctive topical medications have excellent success, with the favored treatment method trending towards topical pharmacotherapy as primary therapy.</p>","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"9 1","pages":"7-15"},"PeriodicalIF":0.9,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-020-00260-y","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39643657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-25DOI: 10.1007/s40135-020-00261-x
Emily Chang, H. Demirci
{"title":"Uveal Melanoma: A Review of Prognostic Factors for Metastases","authors":"Emily Chang, H. Demirci","doi":"10.1007/s40135-020-00261-x","DOIUrl":"https://doi.org/10.1007/s40135-020-00261-x","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"1 1","pages":"1-6"},"PeriodicalIF":0.9,"publicationDate":"2021-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-020-00261-x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43622509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-22DOI: 10.1007/s40135-020-00263-9
E. Attico, G. Galaverni, G. Pellegrini
{"title":"Clinical Studies of COMET for Total LSCD: a Review of the Methods and Molecular Markers for Follow-Up Characterizations","authors":"E. Attico, G. Galaverni, G. Pellegrini","doi":"10.1007/s40135-020-00263-9","DOIUrl":"https://doi.org/10.1007/s40135-020-00263-9","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"9 1","pages":"25-37"},"PeriodicalIF":0.9,"publicationDate":"2021-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-020-00263-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43383944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-12DOI: 10.1007/s40135-020-00262-w
Jane S. Kim, Amal Al-lozi, Ilya M. Leyngold
{"title":"Malignant Orbital Tumors: Current Approach to Diagnosis and Management","authors":"Jane S. Kim, Amal Al-lozi, Ilya M. Leyngold","doi":"10.1007/s40135-020-00262-w","DOIUrl":"https://doi.org/10.1007/s40135-020-00262-w","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"1 1","pages":"1-9"},"PeriodicalIF":0.9,"publicationDate":"2021-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-020-00262-w","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49373422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01Epub Date: 2021-10-22DOI: 10.1007/s40135-021-00280-2
Matthew Bickford, Karolinne Rocha
Purpose of review: In this article, we review the impact of the COVID-19 pandemic on refractive surgery.
Recent findings: COVID-19 infection frequently causes eye symptoms, most commonly conjunctivitis or mild irritation. While virus can be detected in tears of symptomatic patients, the risk of transmission via this route appears low.
Summary: Refractive surgery consultations were significantly reduced during the pandemic; however, volume is rebounding quickly likely due to a number of lifestyle, health, and financial factors. Laser refractive and intraocular surgery likely confer a low risk of virus spread, especially in asymptomatic patients. Screening prior to the refractive consultation and surface disinfection in the clinic and operating room can help reduce transmission risk further.
{"title":"Impact of the COVID-19 Pandemic on Refractive Surgery.","authors":"Matthew Bickford, Karolinne Rocha","doi":"10.1007/s40135-021-00280-2","DOIUrl":"https://doi.org/10.1007/s40135-021-00280-2","url":null,"abstract":"<p><strong>Purpose of review: </strong>In this article, we review the impact of the COVID-19 pandemic on refractive surgery.</p><p><strong>Recent findings: </strong>COVID-19 infection frequently causes eye symptoms, most commonly conjunctivitis or mild irritation. While virus can be detected in tears of symptomatic patients, the risk of transmission via this route appears low.</p><p><strong>Summary: </strong>Refractive surgery consultations were significantly reduced during the pandemic; however, volume is rebounding quickly likely due to a number of lifestyle, health, and financial factors. Laser refractive and intraocular surgery likely confer a low risk of virus spread, especially in asymptomatic patients. Screening prior to the refractive consultation and surface disinfection in the clinic and operating room can help reduce transmission risk further.</p>","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"9 4","pages":"127-132"},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532571/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39579475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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