Pub Date : 2021-12-21DOI: 10.2174/1573401318666211221155620
S. Biswas, A. Bora, P. Mudoi, T. K. Misra, Subrata Das
Protium serratum Engl (Indian red peer) and Artocarpus chama Buch.-Ham (wild jackfruit) are typical wild edible fruits, which have a wide range of folk medicinal properties. Our present study deals with the exploration of nutritional value, antioxidant activity and total phenolic content present in Protium serratum Engl and Artocarpus chama Buch.-Ham fruits. Soxhlet apparatus was used to extract crude samples. The quantitative analysis of the wild edible fruits was broadly done by proximate and ultimate analysis techniques. The results showed that the moisture contents in P. serratum and A. chama Buch. are 78.53% and 74.23%, respectively. The obtained ash (8.59%), fiber (3.17%), total sugar (5.495 mg/100g), and fat (0.66%) contents are high in P. serratum. Whereas, A. chama Buch. has high content of protein (0.52%). Vitamin C content has higher in P. serratum (550 mg/100g) than that of A. chama Buch. (350 mg/100g). The result shows that the Ca and Mg contents have higher in P. serratum compared to A. chama Buch. Indian red peer shows good antioxidant property and has high total phenolic content as compared to wild jackfruit and some commercial fruits. The study establishes that further investigation must be done to find out new products development, processing and preservation techniques so that two underutilized fruits can get into our regular dietary habits. By doing so, we can enrich the fruit basket of the country.
Protium serratum Engl（印度红同行）和Artocarpus chama Buch-火腿（野生菠萝蜜）是典型的野生食用水果，具有广泛的民间药用价值。本研究探讨了锯叶Protium serratum Engl和Artocarpus chama Buch的营养价值、抗氧化活性和总酚含量-火腿水果。使用索氏装置提取粗样品。野生食用水果的定量分析广泛采用近端和末端分析技术。结果表明，锯缘P.serratum和A.chama-Buch。分别为78.53%和74.23%。锯叶P.serratum中灰分（8.59%）、纤维（3.17%）、总糖（5.495mg/100g）和脂肪（0.66%）含量较高。然而，A.chama Buch。锯叶P.serratum的维生素C含量（550mg/100g）高于A.chama-Buch。（350 mg/100g）。结果表明，细齿苋的Ca和Mg含量均高于粗齿苋。与野生菠萝蜜和一些商业水果相比，印度红同行表现出良好的抗氧化性能，并具有高的总酚含量。这项研究表明，必须进行进一步的调查，以找出新产品的开发、加工和保存技术，这样两种未被充分利用的水果才能进入我们的日常饮食习惯。通过这样做，我们可以丰富这个国家的果篮。
{"title":"Evaluation of Nutritional Value, Antioxidant Activity and Phenolic Content of Protium serratum Engl and Artocarpus chama Buch.-Ham, Wild Edible Fruits Available in Tripura, a North- Eastern State of India","authors":"S. Biswas, A. Bora, P. Mudoi, T. K. Misra, Subrata Das","doi":"10.2174/1573401318666211221155620","DOIUrl":"https://doi.org/10.2174/1573401318666211221155620","url":null,"abstract":"\u0000\u0000Protium serratum Engl (Indian red peer) and Artocarpus chama Buch.-Ham (wild jackfruit) are typical wild edible fruits, which have a wide range of folk medicinal properties. \u0000\u0000\u0000\u0000\u0000Our present study deals with the exploration of nutritional value, antioxidant activity and total phenolic content present in Protium serratum Engl and Artocarpus chama Buch.-Ham fruits. \u0000\u0000\u0000\u0000\u0000 Soxhlet apparatus was used to extract crude samples. The quantitative analysis of the wild edible fruits was broadly done by proximate and ultimate analysis techniques. \u0000\u0000\u0000\u0000\u0000The results showed that the moisture contents in P. serratum and A. chama Buch. are 78.53% and 74.23%, respectively. The obtained ash (8.59%), fiber (3.17%), total sugar (5.495 mg/100g), and fat (0.66%) contents are high in P. serratum. Whereas, A. chama Buch. has high content of protein (0.52%). Vitamin C content has higher in P. serratum (550 mg/100g) than that of A. chama Buch. (350 mg/100g). The result shows that the Ca and Mg contents have higher in P. serratum compared to A. chama Buch. Indian red peer shows good antioxidant property and has high total phenolic content as compared to wild jackfruit and some commercial fruits. \u0000\u0000\u0000\u0000\u0000The study establishes that further investigation must be done to find out new products development, processing and preservation techniques so that two underutilized fruits can get into our regular dietary habits. By doing so, we can enrich the fruit basket of the country.\u0000\u0000","PeriodicalId":10944,"journal":{"name":"Current Nutrition & Food Science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44894864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-21DOI: 10.2174/1573401318666211221160338
D. Zhuang, D. Tang, K. Chew, T. Ling
Various research showed that antioxidants can effectively overcome the damage caused by free radicals to the human health. Therefore, antioxidants are identified as one of the main directions in the development of health care and cosmetics products due to high demand in the market. This review mainly focuses on the phycocyanin, a type of natural antioxidant mainly found in cyanobacteria. This mini review summarizes the phycocyanin sources and numerous extraction methods of phycocyanin along with the analytical methods in determining its ability to suppress free radicals. Phycocyanin has been proven to play an important role in scavenging free radicals and enhancing the body’s antioxidant capacity. However, there are lack of long-term randomized clinical trial results that can be used as evidence in showing the benefits of phycocyanin. The existing phycocyanin extraction methods using solvents, ultrasonic-assisted, freeze-thaw and etc. can extract high-quality phycocyanin efficiently and quickly. Scientists are also trying to incorporate advanced technologies such as "Industry 4.0" to optimize and enhance the industrial production of phycocyanin. Lastly, this review also describes the difficulties faced during the phycocyanin production or extraction process and financial obstacles in order to achieve the popularization of phycocyanin.
{"title":"Phycocyanin: A Natural Antioxidant to Combat Free Radicals","authors":"D. Zhuang, D. Tang, K. Chew, T. Ling","doi":"10.2174/1573401318666211221160338","DOIUrl":"https://doi.org/10.2174/1573401318666211221160338","url":null,"abstract":"\u0000\u0000Various research showed that antioxidants can effectively overcome the damage caused by free radicals to the human health. Therefore, antioxidants are identified as one of the main directions in the development of health care and cosmetics products due to high demand in the market. This review mainly focuses on the phycocyanin, a type of natural antioxidant mainly found in cyanobacteria. This mini review summarizes the phycocyanin sources and numerous extraction methods of phycocyanin along with the analytical methods in determining its ability to suppress free radicals. Phycocyanin has been proven to play an important role in scavenging free radicals and enhancing the body’s antioxidant capacity. However, there are lack of long-term randomized clinical trial results that can be used as evidence in showing the benefits of phycocyanin. The existing phycocyanin extraction methods using solvents, ultrasonic-assisted, freeze-thaw and etc. can extract high-quality phycocyanin efficiently and quickly. Scientists are also trying to incorporate advanced technologies such as \"Industry 4.0\" to optimize and enhance the industrial production of phycocyanin. Lastly, this review also describes the difficulties faced during the phycocyanin production or extraction process and financial obstacles in order to achieve the popularization of phycocyanin.\u0000","PeriodicalId":10944,"journal":{"name":"Current Nutrition & Food Science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49474059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-09DOI: 10.2174/1573401317666211209150147
A. Abedini, A. Alizadeh, Aida Mahdavi, S. A. Golzan, Mahla Salimi, Behrouz Tajdar-oranj, H. Hosseini
By-products from the food sector now have a wide range of applications. Low-cost raw materials, followed by low-cost goods, are regarded as one of the sectors’ top goals. Because of its economic relevance, reduced price, and nutrients such as protein, fiber, carbs, and antioxidants, oilseed cakes (OCs) have found a desirable place in livestock and poultry feed. Furthermore, because the cake has the same desirable nutrients, its usage in the food business is unavoidable. However, its use in this sector is not simply for nutritious purposes and has it has different impacts on flavor, texture, color, and antioxidant qualities. Therefore, as a result of its desirable qualities, the cake can be more useful in extensive applications in the food business, as well as in the manufacture of supplements and novel foods. The current review looks at the reapplications of byproducts obtained from oilseeds (soybean, sunflower, sesame, canola, palm kernel, peanut, mustard, and almond) in the food sector in the future. Furthermore, allergenicity, toxicity, antinutritional compounds, and techniques of extracting cakes from oilseeds have been discussed.
{"title":"Oilseed Cakes in the Food Industry: A Review on Applications, Challenges, and Future Perspectives","authors":"A. Abedini, A. Alizadeh, Aida Mahdavi, S. A. Golzan, Mahla Salimi, Behrouz Tajdar-oranj, H. Hosseini","doi":"10.2174/1573401317666211209150147","DOIUrl":"https://doi.org/10.2174/1573401317666211209150147","url":null,"abstract":"\u0000\u0000By-products from the food sector now have a wide range of applications. Low-cost raw\u0000materials, followed by low-cost goods, are regarded as one of the sectors’ top goals. Because of its\u0000economic relevance, reduced price, and nutrients such as protein, fiber, carbs, and antioxidants,\u0000oilseed cakes (OCs) have found a desirable place in livestock and poultry feed. Furthermore, because the cake has the same desirable nutrients, its usage in the food business is unavoidable.\u0000However, its use in this sector is not simply for nutritious purposes and has it has different impacts\u0000on flavor, texture, color, and antioxidant qualities. Therefore, as a result of its desirable qualities,\u0000the cake can be more useful in extensive applications in the food business, as well as in the manufacture of supplements and novel foods. The current review looks at the reapplications of byproducts obtained from oilseeds (soybean, sunflower, sesame, canola, palm kernel, peanut, mustard, and almond) in the food sector in the future. Furthermore, allergenicity, toxicity, antinutritional compounds, and techniques of extracting cakes from oilseeds have been discussed.\u0000","PeriodicalId":10944,"journal":{"name":"Current Nutrition & Food Science","volume":"1 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68170738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-08DOI: 10.2174/1573401317666211208144625
Sheba R. Nakka David, Miza Syazwina Mohammad, L. Y. Chee, Rajan Rajabalaya
The incorporation of oils in the diet may have promoting or inhibitory effects on Colorectal Cancer (CRC). In this study, azoxymethane (AOM) was used to mimic CRC in rats and the effect of sunflower oil on cancer progression in the colon of the rats was tested. This study was conducted to investigate the effect of sunflower oil on preneoplastic cancer properties on the colonic mucosal surface for tumors and the aberrant crypt foci (ACF). Six weeks old Sprague-Dawley male rats were randomized into 4 groups of 6 rats each, namely naïve, positive control, negative control and sunflower oil-fed. CRC was induced by AOM by subcutaneous injection of 20 mg/kg. After CRC induction, the rats were given respective treatment of either basal diet (naïve group), 10 mg/kg indomethacin (positive control), 0.9% saline (negative control), and 7% sunflower oil (experimental group) daily by oral gavage for 42 days. Rats were sacrificed by cervical dislocation; colon samples were visually observed for any tumors on the colonic mucosal surface and evaluated for ACF; histopathological examinations were also performed. The mean body weights of the rats were similar in all groups as per one-way ANOVA. A total of 3 ACF were found in the negative group while none were observed in others. The crypts appeared regular with circular luminal openings and were arranged closely packed together in the naïve group. Crypts in the positive and treated group had a similar appearance like naïve group. Sunflower oil inhibition of the preneoplastic cancer ACF properties were tested but were found to be insignificant when administered during CRC treatment or management. However long-term experiment with a greater number of days will yield better development of tumor and ACF development and will be useful identifying the molecular mechanism.
{"title":"Is Sunflower Cooking Oil Desirable for Colorectal Cancer? In Vivo Studies on Azoxymethane-Induced Colon Cancer in Rats","authors":"Sheba R. Nakka David, Miza Syazwina Mohammad, L. Y. Chee, Rajan Rajabalaya","doi":"10.2174/1573401317666211208144625","DOIUrl":"https://doi.org/10.2174/1573401317666211208144625","url":null,"abstract":"\u0000\u0000The incorporation of oils in the diet may have promoting or inhibitory effects on Colorectal Cancer (CRC). In this study, azoxymethane (AOM) was used to mimic CRC in rats and the effect of sunflower oil on cancer progression in the colon of the rats was tested. \u0000\u0000\u0000\u0000\u0000This study was conducted to investigate the effect of sunflower oil on preneoplastic cancer properties on the colonic mucosal surface for tumors and the aberrant crypt foci (ACF). \u0000\u0000\u0000\u0000\u0000Six weeks old Sprague-Dawley male rats were randomized into 4 groups of 6 rats each, namely naïve, positive control, negative control and sunflower oil-fed. CRC was induced by AOM by subcutaneous injection of 20 mg/kg. After CRC induction, the rats were given respective treatment of either basal diet (naïve group), 10 mg/kg indomethacin (positive control), 0.9% saline (negative control), and 7% sunflower oil (experimental group) daily by oral gavage for 42 days. Rats were sacrificed by cervical dislocation; colon samples were visually observed for any tumors on the colonic mucosal surface and evaluated for ACF; histopathological examinations were also performed.\u0000\u0000\u0000\u0000\u0000 The mean body weights of the rats were similar in all groups as per one-way ANOVA. A total of 3 ACF were found in the negative group while none were observed in others. The crypts appeared regular with circular luminal openings and were arranged closely packed together in the naïve group. Crypts in the positive and treated group had a similar appearance like naïve group. \u0000\u0000\u0000\u0000\u0000 Sunflower oil inhibition of the preneoplastic cancer ACF properties were tested but were found to be insignificant when administered during CRC treatment or management. However long-term experiment with a greater number of days will yield better development of tumor and ACF development and will be useful identifying the molecular mechanism. \u0000\u0000","PeriodicalId":10944,"journal":{"name":"Current Nutrition & Food Science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41877376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-25DOI: 10.2174/1573401317666211125101041
V. Infantino, A. Riva, G. Petrangolini, P. Allegrini, S. Perna, G. Iannello, G. Peroni, C. Gasparri, M. Rondanelli
The increased prevalence of obesity, metabolic syndrome and type 2 diabetes has prompted scientists to look for new active and safe molecules that may help the prevention of metabolic disorders: hyperglycemia, insulin-resistance, dyslipidemia. Berberine is an alkaloid compound derived from plants, and it is largely used in traditional chinese medicine. The aim of this study is to investigate in SCOPUS and Web of Science (WOS) databases how the scientists focused on the use of berberine against metabolic disorders, in human subjects. We carried A bibliometric analysis of scientific literature and performed 2 searches: 1) “Berberine” AND “Diabetes” AND “Diabetes Type 2”, 2) “Berberine” AND “Metabolic Syndrome”, both in ARTICLE (Title/Abstract/Keyword) with a time limitation of 1 January 2000 through 31 December 2018, with the filter on “HUMAN” AND/OR “HUMANS”. The research sorted out 500 papers, finding about 300 (60 %) in the first search definition, and 200 (40 %) in the second. The refined research sorted out 46 papers regarding the use of berberine in diabetes, and 40 articles on the use of the alkaloid compound in the metabolic Syndrome. For both topics, we found increasing interest between 2008 and 2009, with citation trends in a constant crescendo in the overall period studied. These findings underlined that berberine is a safe and interesting botanical compound, especially against chronic-metabolic disorder that affects billions of people globally, and emphasized that scientists are interested in searching for long-term therapies that show no major adverse effects.
肥胖、代谢综合征和2型糖尿病患病率的增加促使科学家寻找新的活性和安全的分子，这些分子可能有助于预防代谢紊乱：高血糖、胰岛素抵抗、血脂异常。黄连素是一种从植物中提取的生物碱化合物，在中药中有广泛的应用。本研究的目的是在SCOPUS和Web of Science（WOS）数据库中调查科学家们是如何专注于在人类受试者中使用黄连素治疗代谢紊乱的。我们对科学文献进行了文献计量学分析，并进行了2次搜索：1）“黄连素”和“糖尿病”和“2型糖尿病”，2）“黄嘌呤”和“代谢综合征”，均在文章（标题/摘要/关键词）中，时间限制为2000年1月1日至2018年12月31日，过滤器为“人类”和/或“人类”。这项研究整理了500篇论文，在第一个搜索定义中发现了大约300篇（60%），在第二个搜索定义下发现了200篇（40%）。这项精细的研究整理了46篇关于黄连素在糖尿病中的应用的论文，以及40篇关于生物碱化合物在代谢综合征中的应用。对于这两个主题，我们发现在2008年至2009年间，人们的兴趣越来越大，在整个研究期间，引文趋势不断增强。这些发现强调，黄连素是一种安全而有趣的植物化合物，尤其是针对影响全球数十亿人的慢性代谢紊乱，并强调科学家有兴趣寻找没有重大不良反应的长期疗法。
{"title":"The Use of Berberine in Diabetes and Metabolic Syndrome: Two Sides of the Same Coin. A Bibliometric Analysis","authors":"V. Infantino, A. Riva, G. Petrangolini, P. Allegrini, S. Perna, G. Iannello, G. Peroni, C. Gasparri, M. Rondanelli","doi":"10.2174/1573401317666211125101041","DOIUrl":"https://doi.org/10.2174/1573401317666211125101041","url":null,"abstract":"\u0000\u0000The increased prevalence of obesity, metabolic syndrome and type 2 diabetes has prompted scientists to look for new active and safe molecules that may help the prevention of metabolic disorders: hyperglycemia, insulin-resistance, dyslipidemia. Berberine is an alkaloid compound derived from plants, and it is largely used in traditional chinese medicine. The aim of this study is to investigate in SCOPUS and Web of Science (WOS) databases how the scientists focused on the use of berberine against metabolic disorders, in human subjects. We carried A bibliometric analysis of scientific literature and performed 2 searches: 1) “Berberine” AND “Diabetes” AND “Diabetes Type 2”, 2) “Berberine” AND “Metabolic Syndrome”, both in ARTICLE (Title/Abstract/Keyword) with a time limitation of 1 January 2000 through 31 December 2018, with the filter on “HUMAN” AND/OR “HUMANS”. The research sorted out 500 papers, finding about 300 (60 %) in the first search definition, and 200 (40 %) in the second. The refined research sorted out 46 papers regarding the use of berberine in diabetes, and 40 articles on the use of the alkaloid compound in the metabolic Syndrome. For both topics, we found increasing interest between 2008 and 2009, with citation trends in a constant crescendo in the overall period studied. These findings underlined that berberine is a safe and interesting botanical compound, especially against chronic-metabolic disorder that affects billions of people globally, and emphasized that scientists are interested in searching for long-term therapies that show no major adverse effects.\u0000","PeriodicalId":10944,"journal":{"name":"Current Nutrition & Food Science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42938642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-22DOI: 10.2174/1573401317666211122144827
K. R. Nair, Arya V.S, Kanthlal S.K., U. P
Hypertension is a global public health concern since it can lead to complications like stroke, heart disease and kidney failure. These complications can add to disability, increase healthcare costs and can even result in mortality. In spite of the availability of a large number of antihypertensive drugs, the control of blood pressure is suboptimal in many patients. Spices have been used as flavouring agent and to treat diseases in folk medicine since they are considered to be rich sources of phytochemicals especially polyphenols. Hence, during recent years there is renewed interest among researchers to explore natural sources, especially spices in an attempt to find cheaper alternatives with fewer side effects. Our aim is to review the relevant preclinical and clinical studies focused towards the potential use of spices in the management of hypertension. Studies conducted on the most common spices such as celery, cinnamon, cardamom, garlic, ginger, saffron, and turmeric, have been elaborated in this review. These spices may be lowering blood pressure via several possible mechanisms including antioxidant effect, increase in nitric oxide production, reduction in calcium ion concentration, modulation of renin angiotensin pathway etc.
{"title":"Spices and Hypertension: An Insight for Researchers","authors":"K. R. Nair, Arya V.S, Kanthlal S.K., U. P","doi":"10.2174/1573401317666211122144827","DOIUrl":"https://doi.org/10.2174/1573401317666211122144827","url":null,"abstract":"\u0000\u0000Hypertension is a global public health concern since it can lead to complications like stroke, heart disease and kidney failure. These complications can add to disability, increase healthcare costs and can even result in mortality. In spite of the availability of a large number of antihypertensive drugs, the control of blood pressure is suboptimal in many patients. Spices have been used as flavouring agent and to treat diseases in folk medicine since they are considered to be rich sources of phytochemicals especially polyphenols. Hence, during recent years there is renewed interest among researchers to explore natural sources, especially spices in an attempt to find cheaper alternatives with fewer side effects. Our aim is to review the relevant preclinical and clinical studies focused towards the potential use of spices in the management of hypertension. Studies conducted on the most common spices such as celery, cinnamon, cardamom, garlic, ginger, saffron, and turmeric, have been elaborated in this review. These spices may be lowering blood pressure via several possible mechanisms including antioxidant effect, increase in nitric oxide production, reduction in calcium ion concentration, modulation of renin angiotensin pathway etc.\u0000","PeriodicalId":10944,"journal":{"name":"Current Nutrition & Food Science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47586208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-10DOI: 10.2174/1573401317666211110104812
G. Mohapatra, Bimala Tripathy, B. Kumar, B. Chowdhury, Rajaram Das
Presence of free radicals in human body are harmful and cell systems are induce many diseases like cardiovascular, diabetes, cancer, inflammation, neuro-degenerative disorder, atherosclerosis, cataract, etc. Antioxidants can balance the effect of free radicals. Antioxidant-rich herbs are identified for preparation of drugs that can be administered to neutralize the free radicals. In the present context the selected medicinal plant is “Origanum majorana” (Family- Lamiaceae) widely known as Marwa in India sub-continent. As the medical professionals show their desires towards composite or lateral treatment, application of drugs with herbal origin gained its importance. This review presented various in vitro and in vivo methods used in the antioxidant activity study of O.majorana and observed its efficacy to reduce oxidative stress. Referred many reliable sources like Research gate, PubMed, Science Direct, Google scholar, Wiley online library, books to collect all information about the antioxidant activity of the selected plant. Used several methods to determine the antioxidants activity of O.majorana, such as superoxide radical scavenging, ferric ion reducing antioxidant potency, thiobarbituric acid reactive substances, hydrogen peroxide scavenging, hydroxyl radical scavenging, lipid peroxidation inhibition, etc. The selected plant contains many phytoconstituents such as gallic acid, ferulic acid, apigenin, catechin, rutin, quercetin, luteolin, linolenic acid, β-sitosterol, and essential oils, which may be responsible for antioxidant activity. The review article provides information for investigating and developing new antioxidant methods and major phytoconstituents from O.majorana for better therapy of oxidative stress-mediated complications.
{"title":"Review on Methods Used to Determine Antioxidant Activity of Origanum majorana","authors":"G. Mohapatra, Bimala Tripathy, B. Kumar, B. Chowdhury, Rajaram Das","doi":"10.2174/1573401317666211110104812","DOIUrl":"https://doi.org/10.2174/1573401317666211110104812","url":null,"abstract":"\u0000\u0000Presence of free radicals in human body are harmful and cell systems are induce many diseases like cardiovascular, diabetes, cancer, inflammation, neuro-degenerative disorder, atherosclerosis, cataract, etc. Antioxidants can balance the effect of free radicals. Antioxidant-rich herbs are identified for preparation of drugs that can be administered to neutralize the free radicals. In the present context the selected medicinal plant is “Origanum majorana” (Family- Lamiaceae) widely known as Marwa in India sub-continent. As the medical professionals show their desires towards composite or lateral treatment, application of drugs with herbal origin gained its importance. \u0000\u0000\u0000\u0000\u0000This review presented various in vitro and in vivo methods used in the antioxidant activity study of O.majorana and observed its efficacy to reduce oxidative stress. \u0000\u0000\u0000\u0000\u0000Referred many reliable sources like Research gate, PubMed, Science Direct, Google scholar, Wiley online library, books to collect all information about the antioxidant activity of the selected plant.\u0000\u0000\u0000\u0000\u0000Used several methods to determine the antioxidants activity of O.majorana, such as superoxide radical scavenging, ferric ion reducing antioxidant potency, thiobarbituric acid reactive substances, hydrogen peroxide scavenging, hydroxyl radical scavenging, lipid peroxidation inhibition, etc. The selected plant contains many phytoconstituents such as gallic acid, ferulic acid, apigenin, catechin, rutin, quercetin, luteolin, linolenic acid, β-sitosterol, and essential oils, which may be responsible for antioxidant activity.\u0000\u0000\u0000\u0000\u0000The review article provides information for investigating and developing new antioxidant methods and major phytoconstituents from O.majorana for better therapy of oxidative stress-mediated complications. \u0000\u0000","PeriodicalId":10944,"journal":{"name":"Current Nutrition & Food Science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46217105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-04DOI: 10.2174/1573401317666211104121725
Latifa Imen Benharrat, Azzeddine Senouci, Wassila Benhabib, K. Mekki
Polycystic ovary syndrome (PCOS) is the most common female endocrine disorder and is accompanied by metabolic syndrome (MS), a risk factor for cardiovascular disorders. To evaluate the effect of Omega 3 on the improvement of some metabolic parameters. Sixty women (29±6 years) with PCOS and MS were randomized into two groups: 30 received supplementation with omega-3 (Doppelherz, Activ, Germany), 3g/day (1g per capsule and 3 capsules/day), (180mg Eicosapentaenoic Acid (EPA)/ 120mg Docosahexaenoic Acid DHA per day), and 30 were used as controls. Blood samples were drawn at baseline (T0), 3 weeks (T1) and 6 weeks (T2) after start of treatment. We analysed glycemia, lipid profile, markers of inflammation and oxidative stress. In omega-3 group compared to control, a reduction (p<0.05) in glucose levels was noted at T1 and T2. C-reactive protein (CRP) concentrations were decreased (-25%) at T2. Oxidative stress remain unchanged, but the activity of superoxide dismutase increased as well as the concentrations of Catalase and thiols at T1 and T2 (p<0.001). Omega 3 supplementation improves hyperglycemia, inflammation, and antioxidant defense in PCOS women with MS, and may lead to decreased cardiovascular complications
{"title":"Omega 3 Supplementation Improves Inflammation and Antioxidant Defense in Women with Polycystic Ovary Syndrome","authors":"Latifa Imen Benharrat, Azzeddine Senouci, Wassila Benhabib, K. Mekki","doi":"10.2174/1573401317666211104121725","DOIUrl":"https://doi.org/10.2174/1573401317666211104121725","url":null,"abstract":"\u0000\u0000 Polycystic ovary syndrome (PCOS) is the most common female\u0000endocrine disorder and is accompanied by metabolic syndrome (MS), a risk factor for cardiovascular disorders.\u0000\u0000\u0000\u0000 To evaluate the effect of Omega 3 on the improvement of some metabolic parameters.\u0000\u0000\u0000\u0000\u0000 Sixty women (29±6 years) with PCOS and MS were randomized into two\u0000groups: 30 received supplementation with omega-3 (Doppelherz, Activ, Germany), 3g/day (1g\u0000per capsule and 3 capsules/day), (180mg Eicosapentaenoic Acid (EPA)/ 120mg Docosahexaenoic Acid DHA per day), and 30 were used as controls. Blood samples were drawn at baseline (T0), 3 weeks (T1) and 6 weeks (T2) after start of treatment. We analysed glycemia, lipid\u0000profile, markers of inflammation and oxidative stress.\u0000\u0000\u0000\u0000\u0000In omega-3 group compared to control, a reduction (p<0.05) in glucose levels was\u0000noted at T1 and T2. C-reactive protein (CRP) concentrations were decreased (-25%) at T2. Oxidative stress remain unchanged, but the activity of superoxide dismutase increased as well as\u0000the concentrations of Catalase and thiols at T1 and T2 (p<0.001).\u0000\u0000\u0000\u0000 Omega 3 supplementation improves hyperglycemia, inflammation, and antioxidant defense in PCOS women with MS, and may lead to decreased cardiovascular complications\u0000","PeriodicalId":10944,"journal":{"name":"Current Nutrition & Food Science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45647792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-01DOI: 10.2174/157340131709210928090852
Andro Doss
He of teaching experience and ten years of research experience in the field of ethnopharmacology. He has received his graduation and post-graduation degrees from St. Joseph’s College, Trichy, India, and Doctor of Philosophy from National College, which is affiliated with Bharathidasan Univer-sity, India. His research areas are ethnopharmacology and Microbial Biotechnology. He has published more than 170 research articles related to ethnomedicinal plants in various international and national peer reviewed refereed journals. He is a resource person in this field. His other works include documentation of ethnomedicinal plants that are endemic to Southern Tamil Nadu. He had also surveyed and documented several ethnomedicinal plants (along with their pharmacognos-tical and pharmacological aspects) in the region of Southern Western Ghats and Tamil Nadu. He also serves as a reviewer for various international journals. His Google Scholar citation is 1137 with an H index of 19 and an I-10 index of 39.
{"title":"Meet the Associate Editorial Board Member","authors":"Andro Doss","doi":"10.2174/157340131709210928090852","DOIUrl":"https://doi.org/10.2174/157340131709210928090852","url":null,"abstract":"He of teaching experience and ten years of research experience in the field of ethnopharmacology. He has received his graduation and post-graduation degrees from St. Joseph’s College, Trichy, India, and Doctor of Philosophy from National College, which is affiliated with Bharathidasan Univer-sity, India. His research areas are ethnopharmacology and Microbial Biotechnology. He has published more than 170 research articles related to ethnomedicinal plants in various international and national peer reviewed refereed journals. He is a resource person in this field. His other works include documentation of ethnomedicinal plants that are endemic to Southern Tamil Nadu. He had also surveyed and documented several ethnomedicinal plants (along with their pharmacognos-tical and pharmacological aspects) in the region of Southern Western Ghats and Tamil Nadu. He also serves as a reviewer for various international journals. His Google Scholar citation is 1137 with an H index of 19 and an I-10 index of 39.","PeriodicalId":10944,"journal":{"name":"Current Nutrition & Food Science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41907401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-10-11DOI: 10.2174/1573401317666211011105732
E. Örs, Ş. Alkan, A. Öksüz
Obesity is defined by the World Health Organisation (WHO) as a body mass index equals to 30 kg/m2 or greater. It is an important and escalating global public health problem. Obesity is known to cause low-grade chronic inflammation, increasing the burden of noncommunicable and possibly communicable diseases. There is considerable evidence that obesity is associated with an increased risk of contracting coronavirus disease 2019 (COVID-19) infection as well as significantly higher COVID-19 morbidity and mortality. It appears plausible that controlling the chronic systemic low-grade inflammation associated with obesity may have a positive impact on the symptoms and the prognosis of COVID-19 disease in obese patients. Astaxanthin (ASTX) is a naturally occurring carotenoid with anti-inflammatory, antioxidant, and immunomodulatory activities. As a nutraceutical agent, it is used as a preventative and a co-treatment in a number of systemic neurological, cardiovascular, and metabolic diseases. This review article will discuss the pathogenesis of COVID-19 infection and the effect of ASTX on obesity and obesity-related inflammation. The potential positive impact of ASTX anti-inflammatory properties in obese COVID-19 patients will be discussed.
{"title":"Possible effect of Astaxanthin on obesity related increased COVID-19 infection morbidity and mortality","authors":"E. Örs, Ş. Alkan, A. Öksüz","doi":"10.2174/1573401317666211011105732","DOIUrl":"https://doi.org/10.2174/1573401317666211011105732","url":null,"abstract":"\u0000\u0000Obesity is defined by the World Health Organisation (WHO) as a body mass index equals to 30 kg/m2 or greater. It is an important and escalating global public health problem. Obesity is known to cause low-grade chronic inflammation, increasing the burden of noncommunicable and possibly communicable diseases. There is considerable evidence that obesity is associated with an increased risk of contracting coronavirus disease 2019 (COVID-19) infection as well as significantly higher COVID-19 morbidity and mortality. It appears plausible that controlling the chronic systemic low-grade inflammation associated with obesity may have a positive impact on the symptoms and the prognosis of COVID-19 disease in obese patients. Astaxanthin (ASTX) is a naturally occurring carotenoid with anti-inflammatory, antioxidant, and immunomodulatory activities. As a nutraceutical agent, it is used as a preventative and a co-treatment in a number of systemic neurological, cardiovascular, and metabolic diseases. This review article will discuss the pathogenesis of COVID-19 infection and the effect of ASTX on obesity and obesity-related inflammation. The potential positive impact of ASTX anti-inflammatory properties in obese COVID-19 patients will be discussed. \u0000","PeriodicalId":10944,"journal":{"name":"Current Nutrition & Food Science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43716143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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