Aim: To determine the accuracy of two electronic apex locators in measuring working length and detecting the location of root perforations. Methodology: A total of 30 distal roots of extracted first maxillary molars were chosen. The actual working length was first measured. The electronic working length was obtained with Root ZX and Raypex 6. The differences between electronic working lengths and actual working length were calculated. Afterwards, the same roots were perforated artificially above the apical foramen. Both devices were utilized to locate perforations in the distal roots. Subsequently, the obtained measurements were compared. Intraoral environment was simulated employing a fixation device. Data were analysed using repeated measures ANOVA, paired sample t test, chi square, and Fisher exact tests. Statistical significance was considered at the 0.05 level. Results: There was no significant difference among electronic working lengths, measured with the two devices, and actual working length (p>0.05). The percentage of accuracy of electronic working lengths, measured by Root ZX and Raypex 6, was 85.7% and 90.9% respectively within a tolerance of ±0.5 mm (p>0.05). Moreover, the difference between the devices was significant with regard to the location of root perforations (p<0.05). Conclusions: Both electronic apex locators were able to determine canal length. Raypex 6 was more accurate than Root ZX in locating root perforations. *Correspondence to: Kaveh Nasiri, DDS, MSc (Endodontics), Department of Endodontics, Center for Operative Dentistry and Periodontology, University of Dental Medicine and Oral Health, Danube Private University, Krems, Austria, E-mail: DDS.Nasiri@web.de
{"title":"Comparing the accuracy of two electronic apex locators in the determination of working length and the detection of root perforations: An in vitro study","authors":"K. Nasiri, K. Wrbas","doi":"10.15761/docr.1000301","DOIUrl":"https://doi.org/10.15761/docr.1000301","url":null,"abstract":"Aim: To determine the accuracy of two electronic apex locators in measuring working length and detecting the location of root perforations. Methodology: A total of 30 distal roots of extracted first maxillary molars were chosen. The actual working length was first measured. The electronic working length was obtained with Root ZX and Raypex 6. The differences between electronic working lengths and actual working length were calculated. Afterwards, the same roots were perforated artificially above the apical foramen. Both devices were utilized to locate perforations in the distal roots. Subsequently, the obtained measurements were compared. Intraoral environment was simulated employing a fixation device. Data were analysed using repeated measures ANOVA, paired sample t test, chi square, and Fisher exact tests. Statistical significance was considered at the 0.05 level. Results: There was no significant difference among electronic working lengths, measured with the two devices, and actual working length (p>0.05). The percentage of accuracy of electronic working lengths, measured by Root ZX and Raypex 6, was 85.7% and 90.9% respectively within a tolerance of ±0.5 mm (p>0.05). Moreover, the difference between the devices was significant with regard to the location of root perforations (p<0.05). Conclusions: Both electronic apex locators were able to determine canal length. Raypex 6 was more accurate than Root ZX in locating root perforations. *Correspondence to: Kaveh Nasiri, DDS, MSc (Endodontics), Department of Endodontics, Center for Operative Dentistry and Periodontology, University of Dental Medicine and Oral Health, Danube Private University, Krems, Austria, E-mail: DDS.Nasiri@web.de","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91195616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In the current study, thermoplasmonic characteristics of Rhodium nanoparticles with spherical, core-shell and rod shapes are investigated. In order to investigate these characteristics, interaction of synchrotron radiation emission as a function of the beam energy and Rhodium nanoparticles were simulated using 3D finite element method. Firstly, absorption and extinction cross sections were calculated. Then, increases in temperature due to synchrotron radiation emission as a function of the beam energy absorption were calculated in Rhodium nanoparticles by solving heat equation. The obtained results show that Rhodium nanorods are more appropriate option for using in optothermal human cancer cells, tissues and tumors treatment method.
{"title":"Appearance check of rhodium nanoparticles delivery trend in human gum cancer cells, tissues and tumors treatment under synchrotron radiation","authors":"A. Heidari, K. Schmitt, M. Henderson, E. Besana","doi":"10.15761/domr.1000323","DOIUrl":"https://doi.org/10.15761/domr.1000323","url":null,"abstract":"In the current study, thermoplasmonic characteristics of Rhodium nanoparticles with spherical, core-shell and rod shapes are investigated. In order to investigate these characteristics, interaction of synchrotron radiation emission as a function of the beam energy and Rhodium nanoparticles were simulated using 3D finite element method. Firstly, absorption and extinction cross sections were calculated. Then, increases in temperature due to synchrotron radiation emission as a function of the beam energy absorption were calculated in Rhodium nanoparticles by solving heat equation. The obtained results show that Rhodium nanorods are more appropriate option for using in optothermal human cancer cells, tissues and tumors treatment method.","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73191544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In recent decade, metallic nanoparticles have been widely interested due to their interesting optical characteristics [1-8]. Resonances of surface Plasmon in these nanoparticles lead to increase in synchrotron radiation emission as a function of the beam energy scattering and absorption in related frequency [9,10]. Synchrotron radiation emission as a function of the beam energy absorption and induced produced heat in nanoparticles has been considered as a side effect in plasmonic applications for a long time [11-15]. Recently, scientists find that thermoplasmonic characteristic can be used for various optothermal applications in cancer, nanoflows and photonic [16-22]. In optothermal human cancer cells, tissues and tumors treatment, the descendent laser light stimulate resonance of surface Plasmon of metallic nanoparticles and as a result of this process, the absorbed energy of descendent light converse to heat in nanoparticles [23-25]. The produced heat devastates tumor tissue adjacent to nanoparticles without any hurt to sound tissues [26,27]. Regarding the simplicity of ligands connection to Ytterbium nanoparticles for targeting cancer cells, these nanoparticles are more appropriate to use in optothermal human cancer cells, tissues and tumors treatment [2874]. In the current paper, thermoplasmonic characteristics of spherical, core-shell and rod Ytterbium nanoparticles are investigated. Abstract
{"title":"Simulation of interaction between ytterbium nanoparticles and human gum cancer cells, tissues and tumors treatment under synchrotron radiation","authors":"A. Heidari, K. Schmitt, M. Henderson, E. Besana","doi":"10.15761/domr.1000311","DOIUrl":"https://doi.org/10.15761/domr.1000311","url":null,"abstract":"In recent decade, metallic nanoparticles have been widely interested due to their interesting optical characteristics [1-8]. Resonances of surface Plasmon in these nanoparticles lead to increase in synchrotron radiation emission as a function of the beam energy scattering and absorption in related frequency [9,10]. Synchrotron radiation emission as a function of the beam energy absorption and induced produced heat in nanoparticles has been considered as a side effect in plasmonic applications for a long time [11-15]. Recently, scientists find that thermoplasmonic characteristic can be used for various optothermal applications in cancer, nanoflows and photonic [16-22]. In optothermal human cancer cells, tissues and tumors treatment, the descendent laser light stimulate resonance of surface Plasmon of metallic nanoparticles and as a result of this process, the absorbed energy of descendent light converse to heat in nanoparticles [23-25]. The produced heat devastates tumor tissue adjacent to nanoparticles without any hurt to sound tissues [26,27]. Regarding the simplicity of ligands connection to Ytterbium nanoparticles for targeting cancer cells, these nanoparticles are more appropriate to use in optothermal human cancer cells, tissues and tumors treatment [2874]. In the current paper, thermoplasmonic characteristics of spherical, core-shell and rod Ytterbium nanoparticles are investigated. Abstract","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88461689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ruby Dwivedi, Rahul Pandey, D. Mehrotra, S. Chandra, D. Parmar
High morbidity and mortality associated with oral cancers and its high incidence and prevalence necessitates earlier diagnosis and effective management. Despite of ease in morphological accessibility, oral cancers are still diagnosed mostly in advanced stages chiefly due to lack of effective and cheap screening tools.The search of a suitable biomarker, which can diagnose, oral cancer effectively and can predict the progression of Oral Potentially malignant Disorders (OMPD) to Oral Cancer with accuracy, still exists. PRAME (Preferentially Expressed Antigen of Melanoma) is one such biomarker, which is a dominant repressor of Vitamin A (Vit A). Vit A, chiefly Retinoic Acid (RA) is extensively used these days for chemoprevention owing to its role in cell growth and differentiation. RA emerged as a cheap and acceptable chemo preventive agent since RA is readily available in the form of Vit A food supplements, Vit A is being used in patients with various grades of OPMDs and oral cancer, but its efficiency is still debatable owing to its mixed results in various cancers. Inconsistency in efficient results led to study of various molecules like PRAME, which is involved in RA metabolic pathway thereby modulating the outcome and efficacy of Retinoic Acid chemoprevention. *Correspondence to: Rahul Pandey, Scientist, DHR-MRU,King George Medical University, Lucknow226003, U.P, India, Tel: 9889175042; E-mail: pandey.rahul.dr@gmail.com
{"title":"PRAME pathway in oral carcinogenesis: A systematic review","authors":"Ruby Dwivedi, Rahul Pandey, D. Mehrotra, S. Chandra, D. Parmar","doi":"10.15761/docr.1000297","DOIUrl":"https://doi.org/10.15761/docr.1000297","url":null,"abstract":"High morbidity and mortality associated with oral cancers and its high incidence and prevalence necessitates earlier diagnosis and effective management. Despite of ease in morphological accessibility, oral cancers are still diagnosed mostly in advanced stages chiefly due to lack of effective and cheap screening tools.The search of a suitable biomarker, which can diagnose, oral cancer effectively and can predict the progression of Oral Potentially malignant Disorders (OMPD) to Oral Cancer with accuracy, still exists. PRAME (Preferentially Expressed Antigen of Melanoma) is one such biomarker, which is a dominant repressor of Vitamin A (Vit A). Vit A, chiefly Retinoic Acid (RA) is extensively used these days for chemoprevention owing to its role in cell growth and differentiation. RA emerged as a cheap and acceptable chemo preventive agent since RA is readily available in the form of Vit A food supplements, Vit A is being used in patients with various grades of OPMDs and oral cancer, but its efficiency is still debatable owing to its mixed results in various cancers. Inconsistency in efficient results led to study of various molecules like PRAME, which is involved in RA metabolic pathway thereby modulating the outcome and efficacy of Retinoic Acid chemoprevention. *Correspondence to: Rahul Pandey, Scientist, DHR-MRU,King George Medical University, Lucknow226003, U.P, India, Tel: 9889175042; E-mail: pandey.rahul.dr@gmail.com","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78045962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gum cancers are cancers that arise from the gum. They are due to the development of abnormal cells that have the ability to invade or spread to other parts of the body. There are three main types of gum cancers: basal-cell gum cancer (BCC), squamous-cell gum cancer (SCC) and melanoma. Batrachotoxin (BTX) is an anti-gum cancer extremely potent cardiotoxic and neurotoxic steroidal alkaloid found in certain species of beetles, birds, and frogs. Batrachotoxin was derived from the Greek word βάτραχος bátrachos "frog". StructurallyAbstract
{"title":"Maitotoxin time–resolved absorption and resonance FT–IR and raman biospectroscopy and density functional theory (DFT) investigation of vibronic–mode coupling structure in vibrational spectra analysis: a spectroscopic study on an anti–gum cancer drug","authors":"A. Heidari, J. Esposito, Angela Caissutti","doi":"10.15761/domr.1000318","DOIUrl":"https://doi.org/10.15761/domr.1000318","url":null,"abstract":"Gum cancers are cancers that arise from the gum. They are due to the development of abnormal cells that have the ability to invade or spread to other parts of the body. There are three main types of gum cancers: basal-cell gum cancer (BCC), squamous-cell gum cancer (SCC) and melanoma. Batrachotoxin (BTX) is an anti-gum cancer extremely potent cardiotoxic and neurotoxic steroidal alkaloid found in certain species of beetles, birds, and frogs. Batrachotoxin was derived from the Greek word βάτραχος bátrachos \"frog\". StructurallyAbstract","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"64 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84738629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Ambayiram, A. Chidembaranathan, Muthukumar Balasubramanium
Overdenture therapy is a kind of preventive prosthodontics treatment modality that preserves the remaining natural teeth and roots. The periodontal membrane with its proprioceptive mechanism can be preserved by the overdenture therapy. This case report presents a tooth supported removable partial denture which influence esthetics and improved function. *Correspondence to: S C Ahila, Associate Professor, Department of Prosthodontics, SRM Dental College, Ramapuram, Chennai-89, India, Tel: 9443607653, E-mail: ahilasc@yahoo.co.in
覆盖义齿治疗是一种保留天然牙和牙根的预防性修复治疗方式。牙周膜及其本体感觉机制可通过覆盖义齿修复得以保留。本病例报告介绍了一种影响美观和改善功能的可摘局部义齿。*通讯:S C Ahila，副教授，SRM牙科学院口腔修复系，印度金奈-89，电话:9443607653,E-mail: ahilasc@yahoo.co.in
{"title":"Coping retained removable partial denture an alternative to fixed partial denture: A case report","authors":"A. Ambayiram, A. Chidembaranathan, Muthukumar Balasubramanium","doi":"10.15761/docr.1000298","DOIUrl":"https://doi.org/10.15761/docr.1000298","url":null,"abstract":"Overdenture therapy is a kind of preventive prosthodontics treatment modality that preserves the remaining natural teeth and roots. The periodontal membrane with its proprioceptive mechanism can be preserved by the overdenture therapy. This case report presents a tooth supported removable partial denture which influence esthetics and improved function. *Correspondence to: S C Ahila, Associate Professor, Department of Prosthodontics, SRM Dental College, Ramapuram, Chennai-89, India, Tel: 9443607653, E-mail: ahilasc@yahoo.co.in","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90988573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In the current study, thermoplasmonic characteristics of Osmium nanoparticles with spherical, core-shell and rod shapes are investigated. In order to investigate these characteristics, interaction of synchrotron radiation emission as a function of the beam energy and Osmium nanoparticles were simulated using 3D finite element method. Firstly, absorption and extinction cross sections were calculated. Then, increases in temperature due to synchrotron radiation emission as a function of the beam energy absorption were calculated in Osmium nanoparticles by solving heat equation. The obtained results show that Osmium nanorods are more appropriate option for using in optothermal human cancer cells, tissues and tumors treatment method. image of Osmium nanoparticles with 50000x
{"title":"Drug delivery systems (DDSs) of osmium nanoparticles on human gum cancer cells, tissues and tumors treatment under synchrotron radiation","authors":"A. Heidari, K. Schmitt, M. Henderson, E. Besana","doi":"10.15761/domr.1000325","DOIUrl":"https://doi.org/10.15761/domr.1000325","url":null,"abstract":"In the current study, thermoplasmonic characteristics of Osmium nanoparticles with spherical, core-shell and rod shapes are investigated. In order to investigate these characteristics, interaction of synchrotron radiation emission as a function of the beam energy and Osmium nanoparticles were simulated using 3D finite element method. Firstly, absorption and extinction cross sections were calculated. Then, increases in temperature due to synchrotron radiation emission as a function of the beam energy absorption were calculated in Osmium nanoparticles by solving heat equation. The obtained results show that Osmium nanorods are more appropriate option for using in optothermal human cancer cells, tissues and tumors treatment method. image of Osmium nanoparticles with 50000x","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89778523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
*Correspondence to: Alireza Heidari, Faculty of Chemistry, California South University, 14731 Comet St. Irvine, CA 92604; American International Standards Institute, Irvine, CA 3800, USA, E-mail: Scholar.Researcher.Scientist@gmail.com; Alireza.Heidari@calsu.us; Central@aisi-usa.org
*通讯:Alireza Heidari，南加州大学化学系，14731 Comet St. Irvine, CA 92604;美国国际标准协会，加州尔湾3800，美国，E-mail: Scholar.Researcher.Scientist@gmail.com;Alireza.Heidari@calsu.us;Central@aisi-usa.org
{"title":"Hafnium nanoparticles and their roles and applications in human gum cancer cells, tissues and tumors treatment under synchrotron radiation","authors":"A. Heidari, K. Schmitt, M. Henderson, E. Besana","doi":"10.15761/domr.1000320","DOIUrl":"https://doi.org/10.15761/domr.1000320","url":null,"abstract":"*Correspondence to: Alireza Heidari, Faculty of Chemistry, California South University, 14731 Comet St. Irvine, CA 92604; American International Standards Institute, Irvine, CA 3800, USA, E-mail: Scholar.Researcher.Scientist@gmail.com; Alireza.Heidari@calsu.us; Central@aisi-usa.org","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"110 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80545450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Vishnu, V. Saxena, Hemant Verma, Vijayta Sharva, N. Jain, Mrinal Sathpathy
India has the third largest HIV epidemic in the world. The HIV/AIDS epidemic constitutes one of the most formidable challenges to development and social progress. Antiretroviral therapy (ART) is the most common treatment provided to HIV/AIDS patients. Oral lesions strongly associated to HIV/AIDS. Moreover, no evidential record of any study on AIDS patients attending retro viral therapy at Bhopal is present. So, a pioneer attempt has been made to assess the oral health status & treatment needs of patients attending anti-retro viral therapy in ART cell, G.M.C Bhopal. Material & methods: A Descriptive cross-sectional study design was employed. Total 320 patients were examined. All patient who reported in unit, since last 3 year were included in the study. data was collected and recorded using printed proforma. Consisted of WHO Oral Health Assessment form 1997. The collected data were coded, and statistical analysis was carried out using Statistical Package of Social Science (SPSS Version 22) chi-square, T test, unpaired T test, ANOVA is used. The statistical significance was fixed at 0.05. Results: A total of 320 study subjects were examined, 202(63.1%) were male and 118(36.8%) were females. 124(38.75%) had ulceration erosion on vermillion border. Total 145(45.3%) AIDS Patients had TMJ symptoms of pain. 7(2.1%) had malignant tumor, 11(3.2%) had leukoplakia, 18(5.8%) had lichen plannus, 98(30.06%) had ulceration, 67(20%) had candidiasis, 57(17.8%) had abscess. Total periodontal disease prevalence was 78.8 %,. Mean DMFT was 3.50±2.18, 50(15.6%) had dental trauma. Overall, one surface filling, two surface filling, extraction & pulp care restorations were most frequent treatment need. Conclusion: The study shows that HIV positive patients have poor oral health status. The use of antiretroviral drugs further depletes their oral health and is responsible for development of periodontal diseases, dental caries and oromucosal lesions. *Correspondence to: Vijayta Sharva, Senior Lecturer, Public Health Dentistry, Peoples Dental Academy, Bhopal (M.P.), India, E-mail: vijaytasharva@gmail.com
印度是世界上第三大艾滋病流行国。艾滋病毒/艾滋病是对发展和社会进步的最严峻挑战之一。抗逆转录病毒疗法(ART)是向艾滋病毒/艾滋病患者提供的最常见的治疗方法。口腔病变与艾滋病毒/艾滋病密切相关。此外，没有任何证据记录表明在博帕尔接受复古病毒治疗的艾滋病患者有任何研究。因此，对ART cell, G.M.C Bhopal接受抗逆转录病毒治疗的患者的口腔健康状况和治疗需求进行了初步的评估。材料与方法:采用描述性横断面研究设计。共检查320例患者。本研究纳入近3年来在本单位就诊的所有患者。数据收集和记录使用印刷形式。由1997年世界卫生组织口腔健康评估表组成。对收集到的数据进行编码，统计分析采用社会科学统计软件包(SPSS Version 22)卡方、T检验、未配对T检验、方差分析。统计学意义为0.05。结果:共纳入研究对象320例，其中男性202例(63.1%)，女性118例(36.8%)。朱砂边溃疡糜烂124例(38.75%)。145例(45.3%)艾滋病患者有颞下颌关节疼痛症状。恶性肿瘤7例(2.1%)，白斑11例(3.2%)，计划地衣18例(5.8%)，溃疡98例(30.06%)，念珠菌病67例(20%)，脓肿57例(17.8%)。牙周病总患病率为78.8%。DMFT平均为3.50±2.18，其中50例(15.6%)有牙外伤。总的来说，单面充填、双面充填、拔牙和牙髓护理修复是最常见的治疗需求。结论:HIV阳性患者口腔健康状况较差。抗逆转录病毒药物的使用进一步损害了他们的口腔健康，并导致牙周病、龋齿和口腔黏膜病变的发生。*通信:Vijayta Sharva，印度博帕尔人民牙科学院公共卫生牙科高级讲师，E-mail: vijaytasharva@gmail.com
{"title":"Oral health status & treatment needs of patient attending anti retro-viral therapy among HIV patient in Government Medical College, Bhopal - A cross-sectional study","authors":"V. Vishnu, V. Saxena, Hemant Verma, Vijayta Sharva, N. Jain, Mrinal Sathpathy","doi":"10.15761/domr.1000310","DOIUrl":"https://doi.org/10.15761/domr.1000310","url":null,"abstract":"India has the third largest HIV epidemic in the world. The HIV/AIDS epidemic constitutes one of the most formidable challenges to development and social progress. Antiretroviral therapy (ART) is the most common treatment provided to HIV/AIDS patients. Oral lesions strongly associated to HIV/AIDS. Moreover, no evidential record of any study on AIDS patients attending retro viral therapy at Bhopal is present. So, a pioneer attempt has been made to assess the oral health status & treatment needs of patients attending anti-retro viral therapy in ART cell, G.M.C Bhopal. Material & methods: A Descriptive cross-sectional study design was employed. Total 320 patients were examined. All patient who reported in unit, since last 3 year were included in the study. data was collected and recorded using printed proforma. Consisted of WHO Oral Health Assessment form 1997. The collected data were coded, and statistical analysis was carried out using Statistical Package of Social Science (SPSS Version 22) chi-square, T test, unpaired T test, ANOVA is used. The statistical significance was fixed at 0.05. Results: A total of 320 study subjects were examined, 202(63.1%) were male and 118(36.8%) were females. 124(38.75%) had ulceration erosion on vermillion border. Total 145(45.3%) AIDS Patients had TMJ symptoms of pain. 7(2.1%) had malignant tumor, 11(3.2%) had leukoplakia, 18(5.8%) had lichen plannus, 98(30.06%) had ulceration, 67(20%) had candidiasis, 57(17.8%) had abscess. Total periodontal disease prevalence was 78.8 %,. Mean DMFT was 3.50±2.18, 50(15.6%) had dental trauma. Overall, one surface filling, two surface filling, extraction & pulp care restorations were most frequent treatment need. Conclusion: The study shows that HIV positive patients have poor oral health status. The use of antiretroviral drugs further depletes their oral health and is responsible for development of periodontal diseases, dental caries and oromucosal lesions. *Correspondence to: Vijayta Sharva, Senior Lecturer, Public Health Dentistry, Peoples Dental Academy, Bhopal (M.P.), India, E-mail: vijaytasharva@gmail.com","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79864742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In the current study, thermoplasmonic characteristics of Iridium nanoparticles with spherical, core-shell and rod shapes are investigated. In order to investigate these characteristics, interaction of synchrotron radiation emission as a function of the beam energy and Iridium nanoparticles were simulated using 3D finite element method. Firstly, absorption and extinction cross sections were calculated. Then, increases in temperature due to synchrotron radiation emission as a function of the beam energy absorption were calculated in Iridium nanoparticles by solving heat equation. The obtained results show that Iridium nanorods are more appropriate option for using in optothermal human cancer cells, tissues and tumors treatment method. of
{"title":"Development of successful formulations for oral drug delivery concepts of iridium nanoparticles in human gum cancer cells, tissues and tumors treatment under synchrotron radiation","authors":"A. Heidari, K. Schmitt, M. Henderson, E. Besana","doi":"10.15761/domr.1000326","DOIUrl":"https://doi.org/10.15761/domr.1000326","url":null,"abstract":"In the current study, thermoplasmonic characteristics of Iridium nanoparticles with spherical, core-shell and rod shapes are investigated. In order to investigate these characteristics, interaction of synchrotron radiation emission as a function of the beam energy and Iridium nanoparticles were simulated using 3D finite element method. Firstly, absorption and extinction cross sections were calculated. Then, increases in temperature due to synchrotron radiation emission as a function of the beam energy absorption were calculated in Iridium nanoparticles by solving heat equation. The obtained results show that Iridium nanorods are more appropriate option for using in optothermal human cancer cells, tissues and tumors treatment method. of","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"72 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85926320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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