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Extended external medial maxillectomy for the management of a large maxilla nasal sinusoidal adenocystic carcinoma – Operative technique 扩大上颌骨内外侧切除术治疗大上颌骨鼻窦腺囊性癌的手术技术
Pub Date : 2019-01-01 DOI: 10.15761/docr.1000294
T. Chow
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引用次数: 0
Batrachotoxin time-resolved absorption and resonance FT-IR and raman biospectroscopy and density functional theory (DFT) investigation of vibronic-mode coupling structure in vibrational spectra analysis: A spectroscopic study on an anti-gum cancer drug 蝙蝠毒素时间分辨吸收和共振傅里叶变换红外光谱和拉曼生物光谱及密度泛函理论(DFT)研究振动光谱分析中的振动模式耦合结构:一种抗牙龈癌药物的光谱研究
Pub Date : 2019-01-01 DOI: 10.15761/domr.1000319
A. Heidari, J. Esposito, Angela Caissutti
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引用次数: 17
Orientation rhenium nanoparticles delivery target on human gum cancer cells, tissues and tumors under synchrotron radiation 同步辐射下定向铼纳米粒子靶向递送人牙龈癌细胞、组织和肿瘤
Pub Date : 2019-01-01 DOI: 10.15761/domr.1000324
A. Heidari, K. Schmitt, M. Henderson, E. Besana
In the current study, thermoplasmonic characteristics of Rhenium nanoparticles with spherical, core-shell and rod shapes are investigated. In order to investigate these characteristics, interaction of synchrotron radiation emission as a function of the beam energy and Rhenium nanoparticles were simulated using 3D finite element method. Firstly, absorption and extinction cross sections were calculated. Then, increases in temperature due to synchrotron radiation emission as a function of the beam energy absorption were calculated in Rhenium nanoparticles by solving heat equation. The obtained results show that Rhenium nanorods are more appropriate option for using in optothermal human cancer cells, tissues and tumors treatment method.
本文研究了球形、核壳和棒状铼纳米粒子的热等离子体特性。为了研究这些特性,采用三维有限元方法模拟了同步辐射发射随光束能量的变化与铼纳米粒子的相互作用。首先计算了吸收和消光截面。然后,通过求解热方程,计算了铼纳米粒子中同步辐射发射引起的温度升高与光束能量吸收的关系。研究结果表明,铼纳米棒是一种更适合用于光热人体癌细胞、组织和肿瘤治疗的方法。
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引用次数: 21
Maxillofacial myiasis in a malignant ulcer: Pouring oil on flame 颌面部恶性溃疡:在火焰上浇油
Pub Date : 2019-01-01 DOI: 10.15761/domr.1000308
N. Jain, Shaji Thomas, A. Pillai, A. Pathak
Myiasis is the parasitic infestation of tissue or organ of animals and human by dipterous larvae (maggots) which lay its eggs on necrotic tissue, open wounds, unbroken skin or mucosa and food. Although myiasis is primarily a disease of cattle and livestock in tropical and underdeveloped countries, human infestation is uncommon and oral myiasis is rarest, found only secondary to systemic illness. Treatment involves manual removal of the maggots with the help of hemostat using turpentine oil with systemic use of Ivermectin, a semi-synthetic macrolide antibiotic. We present a case of 77year-old female diagnosed with myiasis secondary to squamous cell carcinoma of buccal mucosa, its treatment and review of literature. *Correspondence to: Neha Jain, Room No 101, Department of Oral & Maxillofacial Surgery, People’s Dental Academy, Bhopal, India, Email: nehamds26@yahoo.in
蝇蛆病是由双翅幼虫(蛆)寄生在动物和人类的组织或器官上,它们将卵产在坏死组织、开放性伤口、未破损的皮肤或粘膜和食物上。虽然在热带和欠发达国家,蝇蛆病主要是牛和牲畜的一种疾病,但人类感染并不常见,口腔蝇蛆病最为罕见,仅继发于全身性疾病。治疗包括在松节油止血剂的帮助下手动去除蛆,并全身使用伊维菌素,一种半合成的大环内酯类抗生素。我们报告一位77岁女性,诊断为继发于口腔黏膜鳞状细胞癌的蝇蛆病,其治疗方法及文献复习。*通讯:Neha Jain,印度博帕尔人民牙科学院口腔颌面外科101室,Email: nehamds26@yahoo.in
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引用次数: 0
Advantages of lawrencium nanoparticles for human gum cancer cells, tissues and tumors treatment under synchrotron radiation 同步辐射下纳米劳伦斯对人牙龈癌细胞、组织和肿瘤治疗的优势
Pub Date : 2019-01-01 DOI: 10.15761/domr.1000315
A. Heidari, K. Schmitt, M. Henderson, E. Besana
In the current study, thermoplasmonic characteristics of Lawrencium nanoparticles with spherical, core-shell and rod shapes are investigated. In order to investigate these characteristics, interaction of synchrotron radiation emission as a function of the beam energy and Lawrencium nanoparticles were simulated using 3D finite element method. Firstly, absorption and extinction cross sections were calculated. Then, increases in temperature due to synchrotron radiation emission as a function of the beam energy absorption were calculated in Lawrencium nanoparticles by solving heat equation. The obtained results show that Lawrencium nanorods are more appropriate option for using in optothermal human cancer cells, tissues and tumors treatment method. Scanning Electron Microscope (SEM) image of Lawrencium nanoparticles with 50000x zoom.
在本研究中,研究了球形、核壳状和棒状的劳伦斯纳米粒子的热等离子体特性。为了研究这些特性,采用三维有限元方法模拟了同步辐射发射作为光束能量的函数与劳伦斯纳米粒子的相互作用。首先计算了吸收和消光截面。然后,通过求解热方程,计算了同步辐射发射引起的温度升高与光束能量吸收的关系。所获得的结果表明,劳伦斯纳米棒是一种更适合用于光热人体癌细胞、组织和肿瘤治疗的方法。5万倍变焦的扫描电子显微镜(SEM)图像。
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引用次数: 22
Study of berkelium nanoparticles delivery effectiveness and efficiency on human gum cancer cells, tissues and tumors treatment under synchrotron radiation 同步辐射下纳米锫对人牙龈癌细胞、组织和肿瘤的递送效果和效率研究
Pub Date : 2019-01-01 DOI: 10.15761/domr.1000313
A. Heidari, K. Schmitt, M. Henderson, E. Besana
In the current study, thermoplasmonic characteristics of Berkelium nanoparticles with spherical, core-shell and rod shapes are investigated. In order to investigate these characteristics, interaction of synchrotron radiation emission as a function of the beam energy and Berkelium nanoparticles were simulated using 3D finite element method. Firstly, absorption and extinction cross sections were calculated. Then, increases in temperature due to synchrotron radiation emission as a function of the beam energy absorption were calculated in Berkelium nanoparticles by solving heat equation. The obtained results show that Berkelium nanorods are more appropriate option for using in optothermal human cancer cells, tissues and tumors treatment method.
在本研究中,研究了球形、核壳和棒状三种形状的铍纳米粒子的热等离子体特性。为了研究这些特性,采用三维有限元方法模拟了同步辐射发射作为光束能量的函数与铍纳米粒子的相互作用。首先计算了吸收和消光截面。然后,通过求解热方程,计算了同步辐射发射引起的温度升高与光束能量吸收的关系。所获得的结果表明,铍纳米棒是更合适的选择,用于光热人体癌细胞、组织和肿瘤的治疗方法。
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引用次数: 22
Evaluation of volumetric bone loss during osteotomy between crestal implant and basal implant before implant placement 种植体放置前冠状种植体与基底种植体截骨时体积骨损失的评估
Pub Date : 2019-01-01 DOI: 10.15761/domr.1000304
A. Pillai, Shaji Thomas, Ruchi S Dubey, N. Jain
Aim: The purpose of this study was to evaluate the volumetric bone loss during osteotomy using CBCT immediately after placement of BOI (Basal Osseo-integrated Implant) & Crestal implants followed by immediate loading. Material & Methods: The study included 20 patients reporting to the Outpatient department of Oral and Maxillofacial Surgery. The patients were randomly allotted to two groups. Group A (n=10) received BOI implant and Group B (n= 10) received Crestal implants in maxillary & mandibular anterior region. Volumetric analysis was performed with the post-operative radiological examination using cone bean computed tomography (CBCT). Results: The mean volumetric bone loss between Triple Disc BOI & Crestal Implant was 46.91 & 115.55 mm 3 respectively. Conclusion: This study has shown that in patients with atrophied ridges disc implant can be used without any other augmentation procedure whereas in patients with ideal ridges conventional root form implant gives better esthetic & functional results.
目的:本研究的目的是评估BOI(基底骨整合种植体)和嵴种植体放置后立即加载的截骨术中CBCT的体积骨损失。材料与方法:本研究纳入口腔颌面外科门诊20例患者。患者被随机分为两组。A组(n=10)行BOI种植体,B组(n=10)行上颌下颌前区嵴种植体。体积分析与术后使用锥形豆计算机断层扫描(CBCT)进行放射学检查。结果:三联盘BOI和牙冠种植体的平均骨体积损失分别为46.91和115.55 mm 3。结论:本研究表明,在脊型萎缩的患者中,椎间盘种植体可以在没有任何其他增强手术的情况下使用,而在脊型理想的患者中,传统的根状种植体具有更好的美观和功能效果。
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引用次数: 1
Evaluation of genotoxicity and cytotoxicity amongst in dental surgeons and technicians by micronucleus assay 用微核试验评价牙科外科医生和技术人员的遗传毒性和细胞毒性
Pub Date : 2019-01-01 DOI: 10.15761/docr.1000296
Molina Noyola Leonardo Daniel, Coronado Romo María Eugenia, Vázquez Alcaraz Silverio Jafet, Izaguirre Pérez Marian Eliza, A. Evarista, Flores-García Aurelio, Torres-Bugarín Olivia
Introduction: Dental surgeons and technicians are continuously exposed to agents could be affect the genetic material and induce mutations. The aim of this study was to evaluate the genotoxic and cytotoxic occupational risk of dental surgeons and technicians through the micronucleated cells (MNC) and nuclear abnormalities (NA) assay in oral mucosa. Methods: Case-control study. We have collected a buccal mucosa from dental surgeons, dental technicians and healthy individuals (matched by BMI, age and gender). The smears were fixed (ethanol 80%/48 h), stained (orange acridine) and analyzed (microscope, 100×). The frequency of MNC and NA (binucleated cells [BNC], lobulated nucleus [LN], condensed chromatins [CC], karyorrhexis [KR], pyknosis (PN) and karyolysis [KL] were counted in 2,000 cells per participant. Results: 90 samples were collected (26 surgeons, 19 technicians and 45 controls). Compared with controls, exception of PN, in surgeons was higher frequency and positive association of MNC and all NA (p<0.05). Technicians were higher frequency of MNC, BNC, CC, KR and CD (p<0.05). Conclusion: The dental surgeons and technicians have genotoxic and cytotoxic damage, demonstrated by MNC and NA, which are related to an increase risk of cancer, chronic degenerative diseases and premature aging. It is necessary to improve biosecurity actions and implement routine genotoxic risk detection methods. *Correspondence to: Olivia Torres Bugarín, Sistema Nacional de Investigadores II, Laboratorio de Evaluación de Genotóxicos, Programa Internacional de Medicina, Universidad Autónoma de Guadalajara, Av. Patria 1201, Lomas del Valle, Zapopan, Jalisco, México, E-mail: oliviatorres@hotmail.com
简介:口腔外科医生和技术人员持续暴露在可能影响遗传物质和诱发突变的物质中。本研究的目的是通过口腔黏膜微核细胞(MNC)和核异常(NA)测定,评估口腔外科医生和技术人员的遗传毒性和细胞毒性职业风险。方法:病例-对照研究。我们收集了口腔外科医生、牙科技师和健康个体(BMI、年龄和性别相匹配)的口腔黏膜。涂片固定(乙醇80%/48 h),染色(橙吖啶),显微镜下分析(100倍)。在每个参与者2000个细胞中计算MNC和NA(双核细胞[BNC]、分叶细胞核[LN]、凝聚染色质[CC]、核分裂[KR]、固缩(PN)和核溶解[KL]的频率。结果:共收集标本90份(外科医生26份,技术人员19份,对照组45份)。与对照组相比,除PN外,外科医生中MNC与所有NA的发生频率更高,且呈正相关(p<0.05)。技师患MNC、BNC、CC、KR、CD的频率较高(p<0.05)。结论:MNC和NA表明,口腔外科医生和技师存在基因毒性和细胞毒性损伤,这与癌症、慢性退行性疾病和早衰的风险增加有关。有必要加强生物安全行动,实施常规的遗传毒性风险检测方法。*通信:奥利维亚·托雷斯Bugarín,第二国家调查系统,Evaluación de Genotóxicos实验室,国际医学方案,Autónoma瓜达拉哈拉大学,Patria 1201,洛马斯·德尔瓦莱,萨波潘,哈利斯科州,姆姆拉西科,电子邮件:oliviatorres@hotmail.com
{"title":"Evaluation of genotoxicity and cytotoxicity amongst in dental surgeons and technicians by micronucleus assay","authors":"Molina Noyola Leonardo Daniel, Coronado Romo María Eugenia, Vázquez Alcaraz Silverio Jafet, Izaguirre Pérez Marian Eliza, A. Evarista, Flores-García Aurelio, Torres-Bugarín Olivia","doi":"10.15761/docr.1000296","DOIUrl":"https://doi.org/10.15761/docr.1000296","url":null,"abstract":"Introduction: Dental surgeons and technicians are continuously exposed to agents could be affect the genetic material and induce mutations. The aim of this study was to evaluate the genotoxic and cytotoxic occupational risk of dental surgeons and technicians through the micronucleated cells (MNC) and nuclear abnormalities (NA) assay in oral mucosa. Methods: Case-control study. We have collected a buccal mucosa from dental surgeons, dental technicians and healthy individuals (matched by BMI, age and gender). The smears were fixed (ethanol 80%/48 h), stained (orange acridine) and analyzed (microscope, 100×). The frequency of MNC and NA (binucleated cells [BNC], lobulated nucleus [LN], condensed chromatins [CC], karyorrhexis [KR], pyknosis (PN) and karyolysis [KL] were counted in 2,000 cells per participant. Results: 90 samples were collected (26 surgeons, 19 technicians and 45 controls). Compared with controls, exception of PN, in surgeons was higher frequency and positive association of MNC and all NA (p<0.05). Technicians were higher frequency of MNC, BNC, CC, KR and CD (p<0.05). Conclusion: The dental surgeons and technicians have genotoxic and cytotoxic damage, demonstrated by MNC and NA, which are related to an increase risk of cancer, chronic degenerative diseases and premature aging. It is necessary to improve biosecurity actions and implement routine genotoxic risk detection methods. *Correspondence to: Olivia Torres Bugarín, Sistema Nacional de Investigadores II, Laboratorio de Evaluación de Genotóxicos, Programa Internacional de Medicina, Universidad Autónoma de Guadalajara, Av. Patria 1201, Lomas del Valle, Zapopan, Jalisco, México, E-mail: oliviatorres@hotmail.com","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82922705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Evaluation of local – delivery system containing 80% aloe vera gel used as an adjunct to scaling and root planning in chronic periodontitis: A clinical study 评估含有80%芦荟凝胶的局部输送系统作为慢性牙周炎刮治和牙根规划的辅助:一项临床研究
Pub Date : 2019-01-01 DOI: 10.15761/domr.1000309
Prakash Singh, Manish Jain, V. Saxena, Vijayta Sharva, Meenakshi Boddun, N. Jain
Background: Recent interest and advances in the field of alternative medicine has promoted the use of various herbal and natural products for multiple uses in the field of medicine. Aloe vera is one such product exhibiting multiple benefits and has gained considerable importance in clinical research. This clinical study focuses on Aloe vera and highlights its property when used as a medicament in the periodontal pocket. Aim: The aim of this study was Evaluation of local – delivery system containing 80% aloevera gel used as an adjunct to scaling and root planning in chronic periodontitis. Objective: To evaluate the efficacy of Aloevera in reduction of gingivitis and periodontits and to compare the antioxidant level before and after alovera application on test site. Material and method: Present study was conducted among 30 patients having periodontitis. Split mouth design was used. GI, SBI, CPI, LOA & PD were recorded at baseline, 15 days & at 1 month. Immediately after recording all the indices at baseline and prior to drug application, the entire patient underwent scaling and root planning with hand instrument. The aloe vera gel was injected into the pockets with a syringe with blunt needle around the selected teeth in the treatment test site. The control site received only scaling and root planning. Biomechanical analysis-GCF was collected from 15 CP patients before and after treatment. Total antioxidant status was determined using colorimetric method and commercial kits. Result & conclusion: In the present study there was a significant difference in antioxidant level in GCF between test site and control site. Test site showed significant increase in antioxidant level and significant improvement in clinical parameter 2 month after application of aloe vera along with scaling and root planning while on control site there was no significant change in antioxidant level. There was strong significant positive correlation of antioxidant with probing depth and attachment loss. *Correspondence to: Vijayta Sharva, Reader, Public Health Dentistry, Peoples Dental Academy, Bhopal, Madhya Pradesh, India, Tel: 9827563977; E-mail: vijaytasharva@gmail.com
背景:近年来对替代医学领域的兴趣和进展促进了各种草药和天然产品在医学领域的多种用途。芦荟是一种具有多种益处的产品,在临床研究中具有相当大的重要性。本临床研究的重点是芦荟,并强调其特性时,作为药物在牙周袋。目的:本研究的目的是评估含有80%芦荟凝胶的局部给药系统用于慢性牙周炎的洗牙和牙根规划辅助治疗。目的:评价芦荟对牙龈炎、牙周炎的治疗作用,比较芦荟在试验部位应用前后抗氧化水平。材料与方法:本研究对30例牙周炎患者进行研究。采用裂口设计。GI、SBI、CPI、LOA和PD分别在基线、15天和1个月时记录。在基线记录所有指标后和用药前,整个患者立即用手器械进行刮治和根规划。用钝针注射器将芦荟凝胶注射到治疗试验部位选定牙齿周围的口袋中。对照场地只接受了尺度和根系规划。采集15例CP患者治疗前后的生物力学分析- gcf。用比色法和商用试剂盒测定总抗氧化状态。结果与结论:在本研究中,试验点与对照组GCF中抗氧化水平存在显著差异。试验点抗氧化水平显著升高,临床参数显著改善,应用芦荟2个月后,同时进行洗牙和根规划,而对照组抗氧化水平无显著变化。抗氧化剂与探针深度和附着损失呈极显著正相关。*通信:Vijayta Sharva,读者,公共卫生牙科,人民牙科学院,博帕尔,中央邦,印度,电话:9827563977;电子邮件:vijaytasharva@gmail.com
{"title":"Evaluation of local – delivery system containing 80% aloe vera gel used as an adjunct to scaling and root planning in chronic periodontitis: A clinical study","authors":"Prakash Singh, Manish Jain, V. Saxena, Vijayta Sharva, Meenakshi Boddun, N. Jain","doi":"10.15761/domr.1000309","DOIUrl":"https://doi.org/10.15761/domr.1000309","url":null,"abstract":"Background: Recent interest and advances in the field of alternative medicine has promoted the use of various herbal and natural products for multiple uses in the field of medicine. Aloe vera is one such product exhibiting multiple benefits and has gained considerable importance in clinical research. This clinical study focuses on Aloe vera and highlights its property when used as a medicament in the periodontal pocket. Aim: The aim of this study was Evaluation of local – delivery system containing 80% aloevera gel used as an adjunct to scaling and root planning in chronic periodontitis. Objective: To evaluate the efficacy of Aloevera in reduction of gingivitis and periodontits and to compare the antioxidant level before and after alovera application on test site. Material and method: Present study was conducted among 30 patients having periodontitis. Split mouth design was used. GI, SBI, CPI, LOA & PD were recorded at baseline, 15 days & at 1 month. Immediately after recording all the indices at baseline and prior to drug application, the entire patient underwent scaling and root planning with hand instrument. The aloe vera gel was injected into the pockets with a syringe with blunt needle around the selected teeth in the treatment test site. The control site received only scaling and root planning. Biomechanical analysis-GCF was collected from 15 CP patients before and after treatment. Total antioxidant status was determined using colorimetric method and commercial kits. Result & conclusion: In the present study there was a significant difference in antioxidant level in GCF between test site and control site. Test site showed significant increase in antioxidant level and significant improvement in clinical parameter 2 month after application of aloe vera along with scaling and root planning while on control site there was no significant change in antioxidant level. There was strong significant positive correlation of antioxidant with probing depth and attachment loss. *Correspondence to: Vijayta Sharva, Reader, Public Health Dentistry, Peoples Dental Academy, Bhopal, Madhya Pradesh, India, Tel: 9827563977; E-mail: vijaytasharva@gmail.com","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89702317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Computational approach to interaction between synchrotron radiation emission as a function of the beam energy and ruthenium nanoparticles in human gum cancer cells, tissues and tumors treatment 同步辐射发射作为光束能量的函数与钌纳米粒子在人牙龈癌细胞、组织和肿瘤治疗中的相互作用的计算方法
Pub Date : 2019-01-01 DOI: 10.15761/domr.1000322
A. Heidari, K. Schmitt, M. Henderson, E. Besana
In recent decade, metallic nanoparticles have been widely interested due to their interesting optical characteristics [1-8]. Resonances of surface Plasmon in these nanoparticles lead to increase in synchrotron radiation emission as a function of the beam energy scattering and absorption in related frequency [9,10]. Synchrotron radiation emission as a function of the beam energy absorption and induced produced heat in nanoparticles has been considered as a side effect in plasmonic applications for a long time [11-15]. Recently, scientists find that thermoplasmonic characteristic can be used for various optothermal applications in cancer, nanoflows and photonic [16-22]. In optothermal human cancer cells, tissues and tumors treatment, the descendent laser light stimulate resonance of surface Plasmon of metallic nanoparticles and as a result of this process, the absorbed energy of descendent light converse to heat in nanoparticles [23-25]. The produced heat devastates tumor tissue adjacent to nanoparticles without any hurt to Abstract
近十年来,金属纳米颗粒因其有趣的光学特性而受到广泛关注[1-8]。这些纳米颗粒表面等离子体的共振导致同步辐射发射的增加,这是光束能量散射和相关频率吸收的函数[9,10]。长期以来,同步辐射发射作为粒子束能量吸收和诱导产生热的函数一直被认为是等离子体应用中的一个副作用[11-15]。最近,科学家们发现热等离子体特性可用于癌症、纳米流和光子等各种光热应用[16-22]。在光热治疗人类癌细胞、组织和肿瘤中,激光的入射光激发金属纳米粒子表面等离子体共振,从而使入射光吸收的能量转化为纳米粒子中的热量[23-25]。产生的热量破坏肿瘤组织邻近的纳米粒子没有任何伤害抽象
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引用次数: 18
期刊
Dental, Oral and Maxillofacial Research
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