In the current research, diagnosis of gum cancer cells from DNA/RNA using database mining and support vector regression through high resolution 4D HPCH experiment for sequential assignment of 13C–labeled DNAs/RNAs in gum cancer cells are investigated. Diagnosis of gum cancer in biopsy samples relies on morphological analysis using the expertise of histopathologists or cytologists who have many years’ experience in viewing these specimens. This is augmented by techniques which allow gum cancer specific markers to be visualized using diagnosis of gum cancer cells from DNA/RNA using database mining and support vector regression through high resolution 4D HPCH experiment for sequential assignment of 13C–labeled DNAs/RNAs in gum cancer cells, where gene profiles can be visualized using microarray platforms. Characteristic translocations can be detected using fluorescent in situ hybridization (FISH), particularly in haematopathology. The use of optical methods to interrogate gum cancer cells is developing rapidly and diagnosis of gum cancer cells from DNA/RNA using database mining and support vector regression through high resolution 4D HPCH experiment for sequential assignment of 13C–labeled DNAs/RNAs in gum cancer cells provides a new modality, which shows much promise.
{"title":"Diagnosis of gum cancer cells from DNA/RNA using database mining and support vector regression through high resolution 4D HPCH experiment for sequential assignment of 13C–labeled DNAs/RNAs in gum cancer cells","authors":"A. Heidari, R. Gobato","doi":"10.15761/DOMR.1000373","DOIUrl":"https://doi.org/10.15761/DOMR.1000373","url":null,"abstract":"In the current research, diagnosis of gum cancer cells from DNA/RNA using database mining and support vector regression through high resolution 4D HPCH experiment for sequential assignment of 13C–labeled DNAs/RNAs in gum cancer cells are investigated. Diagnosis of gum cancer in biopsy samples relies on morphological analysis using the expertise of histopathologists or cytologists who have many years’ experience in viewing these specimens. This is augmented by techniques which allow gum cancer specific markers to be visualized using diagnosis of gum cancer cells from DNA/RNA using database mining and support vector regression through high resolution 4D HPCH experiment for sequential assignment of 13C–labeled DNAs/RNAs in gum cancer cells, where gene profiles can be visualized using microarray platforms. Characteristic translocations can be detected using fluorescent in situ hybridization (FISH), particularly in haematopathology. The use of optical methods to interrogate gum cancer cells is developing rapidly and diagnosis of gum cancer cells from DNA/RNA using database mining and support vector regression through high resolution 4D HPCH experiment for sequential assignment of 13C–labeled DNAs/RNAs in gum cancer cells provides a new modality, which shows much promise.","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"55 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73572809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In the current work, simultaneous detection of intra– and inter–molecular paramagnetic relaxation enhancements in DNA/RNA of gum cancer cells–anti–cancer Nano drugs complexes are studied. A technique that helps to achieve representative biopsies and that would enable accurate and early in vivo diagnosis is needed. This tool should detect lesions in pre–malignant/early stages and assess large tissue areas in real–time to decrease sampling errors. Several techniques have been tested for biopsy guidance, such as optical coherence tomography (OCT), white light reflectance (WLR), simultaneous detection of intra– and inter–molecular paramagnetic relaxation enhancements in DNA/RNA of gum cancer cells–anti–cancer Nano drugs complexes.
{"title":"Simultaneous detection of intra– and inter–molecular paramagnetic relaxation enhancements in DNA/RNA of gum cancer cells–anti–cancer nano drugs complexes","authors":"A. Heidari, R. Gobato","doi":"10.15761/DOMR.1000370","DOIUrl":"https://doi.org/10.15761/DOMR.1000370","url":null,"abstract":"In the current work, simultaneous detection of intra– and inter–molecular paramagnetic relaxation enhancements in DNA/RNA of gum cancer cells–anti–cancer Nano drugs complexes are studied. A technique that helps to achieve representative biopsies and that would enable accurate and early in vivo diagnosis is needed. This tool should detect lesions in pre–malignant/early stages and assess large tissue areas in real–time to decrease sampling errors. Several techniques have been tested for biopsy guidance, such as optical coherence tomography (OCT), white light reflectance (WLR), simultaneous detection of intra– and inter–molecular paramagnetic relaxation enhancements in DNA/RNA of gum cancer cells–anti–cancer Nano drugs complexes.","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80013439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In recent decade, metallic nanoparticles have been widely interested due to their interesting optical characteristics [1-8]. Resonances of surface Plasmon in these nanoparticles lead to increase in synchrotron radiation emission as a function of the beam energy scattering and absorption in related frequency [9,10]. Synchrotron radiation emission as a function of the beam energy absorption and induced produced heat in nanoparticles has been considered as a side effect in plasmonic applications for a long time [11-15]. Recently, scientists find that thermoplasmonic characteristic can be used for various optothermal applications in cancer, nanoflows and photonic [16-22]. In optothermal human cancer cells, tissues and tumors treatment, the descendent laser light stimulate resonance of surface Plasmon of metallic nanoparticles and as a result of this process, the absorbed energy of descendent light converse to heat in nanoparticles [23-25]. The produced heat devastates tumor tissue adjacent to nanoparticles without any hurt to sound tissues [26,27]. Regarding the simplicity of Abstract
{"title":"Types of drug delivery system slide share of protactinium nanoparticles in human gum cancer cells, tissues and tumors treatment under synchrotron radiation","authors":"A. Heidari, K. Schmitt, M. Henderson, E. Besana","doi":"10.15761/domr.1000331","DOIUrl":"https://doi.org/10.15761/domr.1000331","url":null,"abstract":"In recent decade, metallic nanoparticles have been widely interested due to their interesting optical characteristics [1-8]. Resonances of surface Plasmon in these nanoparticles lead to increase in synchrotron radiation emission as a function of the beam energy scattering and absorption in related frequency [9,10]. Synchrotron radiation emission as a function of the beam energy absorption and induced produced heat in nanoparticles has been considered as a side effect in plasmonic applications for a long time [11-15]. Recently, scientists find that thermoplasmonic characteristic can be used for various optothermal applications in cancer, nanoflows and photonic [16-22]. In optothermal human cancer cells, tissues and tumors treatment, the descendent laser light stimulate resonance of surface Plasmon of metallic nanoparticles and as a result of this process, the absorbed energy of descendent light converse to heat in nanoparticles [23-25]. The produced heat devastates tumor tissue adjacent to nanoparticles without any hurt to sound tissues [26,27]. Regarding the simplicity of Abstract","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90607747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In the current study, exact NMR simulation of anti–cancer Nano drug–DNA/RNA complexes in gum cancer cells spin systems using tensor train formalism are considered. Looking into the future, we would predict three promising directions. One is the rapid histology based on two–color exact NMR simulation of anti–cancer Nano drug–DNA/RNA complexes in gum cancer cells spin systems using tensor train formalism which can be used in operation room during gum cancer surgery. The second is in situ molecule–based diagnosis using handheld fast exact NMR simulation of anti–cancer Nano drug–DNA/RNA complexes in gum cancer cells spin systems using tensor train formalism, for example, handheld exact NMR simulation of anti–cancer Nano drug–DNA/RNA complexes in gum cancer cells spin systems using tensor train formalism or hyperspectral exact NMR simulation of anti–cancer Nano drug–DNA/RNA complexes in gum cancer cells spin systems using tensor train formalism. The third is multimodal imaging and spectroscopy system that integrate advantages of each modality and may offer better diagnosis for gum cancer.
本研究利用张量列形式化方法，研究了牙龈癌细胞自旋系统中抗癌纳米药物- dna /RNA复合物的精确核磁共振模拟。展望未来，我们可以预测三个有希望的方向。一是利用张量列形式化方法，基于双色精确核磁共振模拟牙龈癌细胞自旋系统中抗癌纳米药物- dna /RNA复合物的快速组织，可用于牙龈癌手术的手术室。第二种是基于原位分子的诊断，使用张量列形式，使用手持式快速精确核磁共振模拟牙龈癌细胞自旋系统中的抗癌纳米药物- dna /RNA复合物，例如，使用张量列形式，手持式精确核磁共振模拟牙龈癌细胞自旋系统中的抗癌纳米药物- dna /RNA复合物，或者使用张量列形式，使用高光谱精确核磁共振模拟牙龈癌细胞自旋系统中的抗癌纳米药物- dna /RNA复合物。第三种是多模态成像和光谱系统，它综合了每种模态的优点，可以更好地诊断牙龈癌。
{"title":"Exact NMR simulation of anti–cancer nano drug–DNA/RNA complexes in gum cancer cells spin systems using tensor train formalism","authors":"A. Heidari, R. Gobato","doi":"10.15761/DOMR.1000364","DOIUrl":"https://doi.org/10.15761/DOMR.1000364","url":null,"abstract":"In the current study, exact NMR simulation of anti–cancer Nano drug–DNA/RNA complexes in gum cancer cells spin systems using tensor train formalism are considered. Looking into the future, we would predict three promising directions. One is the rapid histology based on two–color exact NMR simulation of anti–cancer Nano drug–DNA/RNA complexes in gum cancer cells spin systems using tensor train formalism which can be used in operation room during gum cancer surgery. The second is in situ molecule–based diagnosis using handheld fast exact NMR simulation of anti–cancer Nano drug–DNA/RNA complexes in gum cancer cells spin systems using tensor train formalism, for example, handheld exact NMR simulation of anti–cancer Nano drug–DNA/RNA complexes in gum cancer cells spin systems using tensor train formalism or hyperspectral exact NMR simulation of anti–cancer Nano drug–DNA/RNA complexes in gum cancer cells spin systems using tensor train formalism. The third is multimodal imaging and spectroscopy system that integrate advantages of each modality and may offer better diagnosis for gum cancer.","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90244428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In the oral cavity of the human body, there are three major salivary glands; parotid, submandibular, and sublingual as well as 300 to 400 minor salivary glands, all of which secret saliva. Saliva consists of proteins, hormones, antibodies and other molecular compounds that are typically measured in a routine blood test. Therefore, saliva is considered as a diagnostic window for the detection of various diseases, such as oral cancer, periodontal diseases, and COVID-19 [1,2]. This brief letter focused on the detection of COVID-19 using saliva samples as a form of liquid biopsy via point-of-care technology.
{"title":"Human saliva as an effective sample for the detection of COVID-19","authors":"K. Nasiri","doi":"10.15761/DOMR.1000358","DOIUrl":"https://doi.org/10.15761/DOMR.1000358","url":null,"abstract":"In the oral cavity of the human body, there are three major salivary glands; parotid, submandibular, and sublingual as well as 300 to 400 minor salivary glands, all of which secret saliva. Saliva consists of proteins, hormones, antibodies and other molecular compounds that are typically measured in a routine blood test. Therefore, saliva is considered as a diagnostic window for the detection of various diseases, such as oral cancer, periodontal diseases, and COVID-19 [1,2]. This brief letter focused on the detection of COVID-19 using saliva samples as a form of liquid biopsy via point-of-care technology.","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"135 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76893320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background : Dental condensable composite resins were used as a substitute for dental amalgam to restore posterior teeth. They were be condensed as dental amalgam, which made it easier to produce an accurate proximal teeth contact. Objectives: The aim of this study was to measure the top and bottom hardness of two condensable composites at different thicknesses (2,3,4 and 5 mm) at different loads (25,50 and 100 gf). Percent depth of cure was calculated for both materials at the different thicknesses. The correlation between the hardness and percent depth of cure was calculated. Materials and methods : The materials used were Glacier and SureFil condensable composite resins. 120 specimens were prepared from both composite resins, 60 specimens each using transparent Perspex molds of 4mm diameter and thicknesses of 2,3,4,5 mm. Specimens of each composite resin were divided into 4 groups corresponding to the different thicknesses, 15 specimens for each thickness. Specimens for each thickness were further divided into 3 subgroups, 5 specimens for each load applied during hardness testing (25, 50 and 100gf). The hardness was measured using a universal micro hardness testing machine for the top and bottom surfaces of each specimen. Percent depth of cure was calculated by dividing the bottom hardness value by the top hardness value and multiplied by 100. Also, the correlation between the hardness and percent depth of cure was calculated . Results : The results indicated that, the top hardness values were greater than that of the bottom hardness values for both composite resins. Glacier composite showed that, the hardness was increased by increasing the testing loads and decreased by increasing the thickness, except at 3 mm thickness of Glacier, which showed higher hardness than 2 mm thickness. Also, SureFil composite resin showed increased hardness values by increasing the testing loads and decreased by increasing the thickness. The hardness of 3mm thickness was greater than that of 2mm thickness. The percent depth of cure in 2mm and 3mm thicknesses were more than 80%, while the other thicknesses showed percent depth of cure less than 80%. Both materials showed high positive correlation between the hardness and percent depth of cure . Conclusions : The top hardness was greater than that of the bottom hardness. The hardness of 3mm thickness was greater than that of 2mm thickness. The hardness was increased by increasing the testing loads and decreased by increasing the thickness. The percent depth of cure was decreased by increasing thickness. There was high positive correlation between the hardness and percent depth of cure .
{"title":"Effect and correlation of testing load and specimen’s thickness on the hardness and percent depth of cure of condensable composite resins","authors":"I. M. Hamouda, Majed Abudllah Mohammed Almalki","doi":"10.15761/DOMR.1000357","DOIUrl":"https://doi.org/10.15761/DOMR.1000357","url":null,"abstract":"Background : Dental condensable composite resins were used as a substitute for dental amalgam to restore posterior teeth. They were be condensed as dental amalgam, which made it easier to produce an accurate proximal teeth contact. Objectives: The aim of this study was to measure the top and bottom hardness of two condensable composites at different thicknesses (2,3,4 and 5 mm) at different loads (25,50 and 100 gf). Percent depth of cure was calculated for both materials at the different thicknesses. The correlation between the hardness and percent depth of cure was calculated. Materials and methods : The materials used were Glacier and SureFil condensable composite resins. 120 specimens were prepared from both composite resins, 60 specimens each using transparent Perspex molds of 4mm diameter and thicknesses of 2,3,4,5 mm. Specimens of each composite resin were divided into 4 groups corresponding to the different thicknesses, 15 specimens for each thickness. Specimens for each thickness were further divided into 3 subgroups, 5 specimens for each load applied during hardness testing (25, 50 and 100gf). The hardness was measured using a universal micro hardness testing machine for the top and bottom surfaces of each specimen. Percent depth of cure was calculated by dividing the bottom hardness value by the top hardness value and multiplied by 100. Also, the correlation between the hardness and percent depth of cure was calculated . Results : The results indicated that, the top hardness values were greater than that of the bottom hardness values for both composite resins. Glacier composite showed that, the hardness was increased by increasing the testing loads and decreased by increasing the thickness, except at 3 mm thickness of Glacier, which showed higher hardness than 2 mm thickness. Also, SureFil composite resin showed increased hardness values by increasing the testing loads and decreased by increasing the thickness. The hardness of 3mm thickness was greater than that of 2mm thickness. The percent depth of cure in 2mm and 3mm thicknesses were more than 80%, while the other thicknesses showed percent depth of cure less than 80%. Both materials showed high positive correlation between the hardness and percent depth of cure . Conclusions : The top hardness was greater than that of the bottom hardness. The hardness of 3mm thickness was greater than that of 2mm thickness. The hardness was increased by increasing the testing loads and decreased by increasing the thickness. The percent depth of cure was decreased by increasing thickness. There was high positive correlation between the hardness and percent depth of cure .","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77705369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In the current research, NMR and molecular dynamics studies combined to anti–cancer Nano drugs and DNA/RNA interactions in gum cancer cells and their modulations with resistance mutations are considered. The early diagnosis of cancer is very important for patient treatment and recovery. If cancers can be confirmed and classified at an early stage, the patient survival rate can be greatly improved. Current clinical cancer diagnostic techniques can be divided into two catalogs: tissue imaging and NMR and molecular dynamics studies combined to anti–cancer Nano drugs and DNA/RNA interactions in gum cancer cells and their modulations with resistance mutations. *Correspondence to: Alireza Heidari, Faculty of Chemistry, California South University, 14731 Comet St. Irvine, CA 92604; American International Standards Institute, Irvine, CA 3800, USA, E-mail: Scholar.Researcher.Scientist@gmail. com; Alireza.Heidari@calsu.us; Central@aisi-usa.org
在目前的研究中，考虑了核磁共振和分子动力学结合抗癌纳米药物和DNA/RNA在牙龈癌细胞中的相互作用及其对耐药突变的调节。癌症的早期诊断对患者的治疗和康复非常重要。如果癌症能够在早期得到确认和分类，患者的存活率可以大大提高。目前的临床癌症诊断技术可分为两大类:组织成像和核磁共振以及结合抗癌纳米药物和牙龈癌细胞中DNA/RNA相互作用及其对耐药突变的调节的分子动力学研究。*通讯:Alireza Heidari，南加州大学化学系，14731 Comet St. Irvine, CA 92604;美国国际标准协会，Irvine, CA 3800, USA, E-mail: Scholar.Researcher.Scientist@gmailcom;Alireza.Heidari@calsu.us;Central@aisi-usa.org
{"title":"NMR and molecular dynamics studies combined to anti–cancer nano drugs and DNA/RNA interactions in gum cancer cells and their modulations with resistance mutations","authors":"A. Heidari, R. Gobato","doi":"10.15761/DOMR.1000368","DOIUrl":"https://doi.org/10.15761/DOMR.1000368","url":null,"abstract":"In the current research, NMR and molecular dynamics studies combined to anti–cancer Nano drugs and DNA/RNA interactions in gum cancer cells and their modulations with resistance mutations are considered. The early diagnosis of cancer is very important for patient treatment and recovery. If cancers can be confirmed and classified at an early stage, the patient survival rate can be greatly improved. Current clinical cancer diagnostic techniques can be divided into two catalogs: tissue imaging and NMR and molecular dynamics studies combined to anti–cancer Nano drugs and DNA/RNA interactions in gum cancer cells and their modulations with resistance mutations. *Correspondence to: Alireza Heidari, Faculty of Chemistry, California South University, 14731 Comet St. Irvine, CA 92604; American International Standards Institute, Irvine, CA 3800, USA, E-mail: Scholar.Researcher.Scientist@gmail. com; Alireza.Heidari@calsu.us; Central@aisi-usa.org","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90312816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In the current paper, impact of DNA/RNA self–alignment in a strong magnetic field on the interpretation of indirect spin–spin interactions using NMR line shape analysis of a multi–state DNA/RNA ligand binding mechanism in gum cancer cells are studied. After diagnosis the primary treatment for solid tumors is often surgery. The objective of surgical treatment is resection of all malignant tissue with adequate resection margins while preserving important healthy structures. Achieving adequate surgical margins is important for disease control and survival. Residual tumor after surgery is associated with poor survival and the need for additional surgery, adjuvant chemotherapy, radiation therapy, or impact of DNA/RNA self–alignment in a strong magnetic field on the interpretation of indirect spin–spin interactions using NMR line shape analysis of a multi–state DNA/RNA ligand binding mechanism in gum cancer cells. A number of studies have shown that the 5–year survival decreases significantly when impact of DNA/RNA self–alignment in a strong magnetic field on the interpretation of indirect spin–spin interactions using NMR line shape analysis of a multi–state DNA/RNA ligand binding mechanism in gum cancer cells. Intraoperative guidance tools can help to achieve adequate surgery. However, there are no widely used intraoperative guidance tools available yet. Current surgical resection techniques are based on subjective methods, such as palpation and visual inspection, to judge the border between normal and cancerous tissue. line of a multi–state DNA/RNA ligand binding
{"title":"Impact of DNA/RNA self–alignment in a strong magnetic field on the interpretation of indirect spin–spin interactions using NMR line shape analysis of a multi–state DNA/RNA ligand binding mechanism in gum cancer cells","authors":"A. Heidari, R. Gobato","doi":"10.15761/DOMR.1000371","DOIUrl":"https://doi.org/10.15761/DOMR.1000371","url":null,"abstract":"In the current paper, impact of DNA/RNA self–alignment in a strong magnetic field on the interpretation of indirect spin–spin interactions using NMR line shape analysis of a multi–state DNA/RNA ligand binding mechanism in gum cancer cells are studied. After diagnosis the primary treatment for solid tumors is often surgery. The objective of surgical treatment is resection of all malignant tissue with adequate resection margins while preserving important healthy structures. Achieving adequate surgical margins is important for disease control and survival. Residual tumor after surgery is associated with poor survival and the need for additional surgery, adjuvant chemotherapy, radiation therapy, or impact of DNA/RNA self–alignment in a strong magnetic field on the interpretation of indirect spin–spin interactions using NMR line shape analysis of a multi–state DNA/RNA ligand binding mechanism in gum cancer cells. A number of studies have shown that the 5–year survival decreases significantly when impact of DNA/RNA self–alignment in a strong magnetic field on the interpretation of indirect spin–spin interactions using NMR line shape analysis of a multi–state DNA/RNA ligand binding mechanism in gum cancer cells. Intraoperative guidance tools can help to achieve adequate surgery. However, there are no widely used intraoperative guidance tools available yet. Current surgical resection techniques are based on subjective methods, such as palpation and visual inspection, to judge the border between normal and cancerous tissue. line of a multi–state DNA/RNA ligand binding","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82389937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The first case is a 5 years 8 months old Antillean girl, presenting an articulated complete cross-bite of the whole arch (Figure 1). The maxilla is hypoplastic in the anteroposterior and transverse directions, without any lateral deviation of the mandible, the overbite is reversed but normal in quantity. This is at primary teeth stage, without any diastemas, the lower teeth are tipped lingually to try to compensate for the discrepancy.
{"title":"Functional treatment of maxillary hypoplasia and mandibular prognathism","authors":"Ben Younes-Uzan Carine, Benichou Laurence","doi":"10.15761/DOMR.1000349","DOIUrl":"https://doi.org/10.15761/DOMR.1000349","url":null,"abstract":"The first case is a 5 years 8 months old Antillean girl, presenting an articulated complete cross-bite of the whole arch (Figure 1). The maxilla is hypoplastic in the anteroposterior and transverse directions, without any lateral deviation of the mandible, the overbite is reversed but normal in quantity. This is at primary teeth stage, without any diastemas, the lower teeth are tipped lingually to try to compensate for the discrepancy.","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"1081 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76702141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In recent decade, metallic nanoparticles have been widely interested due to their interesting optical characteristics [1-8]. Resonances of surface Plasmon in these nanoparticles lead to increase in synchrotron radiation emission as a function of the beam energy scattering and absorption in related frequency [9,10]. Synchrotron radiation emission as a function of the beam energy absorption and induced produced heat in nanoparticles has been considered as a side effect in plasmonic applications for a long time [11-15]. Recently, scientists find that thermoplasmonic characteristic can be used for various optothermal applications in cancer, nanoflows and photonic [16-22]. In optothermal human cancer cells, tissues and tumors treatment, the descendent laser light stimulate resonance of surface Plasmon of metallic nanoparticles and as a result of this process, the absorbed energy of descendent light converse to heat in nanoparticles [23-25]. The produced heat devastates tumor tissue adjacent to nanoparticles without any hurt to sound tissues [26,27]. Regarding the simplicity of ligands connection to Roentgenium nanoparticles for targeting cancer cells, these nanoparticles are more appropriate to use in optothermal human cancer cells, tissues and tumors treatment [28-74]. In the current paper, thermoplasmonic characteristics of spherical, core-shell and rod Roentgenium nanoparticles are investigated. Abstract
{"title":"Pros and cons of the roentgenium nanoparticles for human gum cancer cells, tissues and tumors treatment under synchrotron radiation","authors":"A. Heidari, K. Schmitt, M. Henderson, E. Besana","doi":"10.15761/domr.1000316","DOIUrl":"https://doi.org/10.15761/domr.1000316","url":null,"abstract":"In recent decade, metallic nanoparticles have been widely interested due to their interesting optical characteristics [1-8]. Resonances of surface Plasmon in these nanoparticles lead to increase in synchrotron radiation emission as a function of the beam energy scattering and absorption in related frequency [9,10]. Synchrotron radiation emission as a function of the beam energy absorption and induced produced heat in nanoparticles has been considered as a side effect in plasmonic applications for a long time [11-15]. Recently, scientists find that thermoplasmonic characteristic can be used for various optothermal applications in cancer, nanoflows and photonic [16-22]. In optothermal human cancer cells, tissues and tumors treatment, the descendent laser light stimulate resonance of surface Plasmon of metallic nanoparticles and as a result of this process, the absorbed energy of descendent light converse to heat in nanoparticles [23-25]. The produced heat devastates tumor tissue adjacent to nanoparticles without any hurt to sound tissues [26,27]. Regarding the simplicity of ligands connection to Roentgenium nanoparticles for targeting cancer cells, these nanoparticles are more appropriate to use in optothermal human cancer cells, tissues and tumors treatment [28-74]. In the current paper, thermoplasmonic characteristics of spherical, core-shell and rod Roentgenium nanoparticles are investigated. Abstract","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78651380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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